[{"acknowledgement":"Funded by Austrian Science Fund (FWF) Grant Number: P 22189-B18; European Union within the 6th Framework Programme Grant Number: 517590; State government of Styria Grant Number: PN 4055","scopus_import":"1","ddc":["000"],"intvolume":"        51","month":"02","volume":51,"author":[{"full_name":"Körner, Christof","last_name":"Körner","first_name":"Christof"},{"last_name":"Braunstein","full_name":"Braunstein, Verena","first_name":"Verena"},{"first_name":"Matthias","last_name":"Stangl","full_name":"Stangl, Matthias"},{"orcid":"0000-0002-5621-8100","last_name":"Schlögl","full_name":"Schlögl, Alois","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","first_name":"Alois"},{"first_name":"Christa","last_name":"Neuper","full_name":"Neuper, Christa"},{"full_name":"Ischebeck, Anja","last_name":"Ischebeck","first_name":"Anja"}],"department":[{"_id":"ScienComp"},{"_id":"PeJo"}],"isi":1,"publication_status":"published","pubrep_id":"442","oa_version":"Published Version","page":"385 - 395","language":[{"iso":"eng"}],"has_accepted_license":"1","issue":"4","citation":{"ista":"Körner C, Braunstein V, Stangl M, Schlögl A, Neuper C, Ischebeck A. 2014. Sequential effects in continued visual search: Using fixation-related potentials to compare distractor processing before and after target detection. Psychophysiology. 51(4), 385–395.","mla":"Körner, Christof, et al. “Sequential Effects in Continued Visual Search: Using Fixation-Related Potentials to Compare Distractor Processing before and after Target Detection.” <i>Psychophysiology</i>, vol. 51, no. 4, Wiley-Blackwell, 2014, pp. 385–95, doi:<a href=\"https://doi.org/10.1111/psyp.12062\">10.1111/psyp.12062</a>.","ieee":"C. Körner, V. Braunstein, M. Stangl, A. Schlögl, C. Neuper, and A. Ischebeck, “Sequential effects in continued visual search: Using fixation-related potentials to compare distractor processing before and after target detection,” <i>Psychophysiology</i>, vol. 51, no. 4. Wiley-Blackwell, pp. 385–395, 2014.","chicago":"Körner, Christof, Verena Braunstein, Matthias Stangl, Alois Schlögl, Christa Neuper, and Anja Ischebeck. “Sequential Effects in Continued Visual Search: Using Fixation-Related Potentials to Compare Distractor Processing before and after Target Detection.” <i>Psychophysiology</i>. Wiley-Blackwell, 2014. <a href=\"https://doi.org/10.1111/psyp.12062\">https://doi.org/10.1111/psyp.12062</a>.","short":"C. Körner, V. Braunstein, M. Stangl, A. Schlögl, C. Neuper, A. Ischebeck, Psychophysiology 51 (2014) 385–395.","apa":"Körner, C., Braunstein, V., Stangl, M., Schlögl, A., Neuper, C., &#38; Ischebeck, A. (2014). Sequential effects in continued visual search: Using fixation-related potentials to compare distractor processing before and after target detection. <i>Psychophysiology</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/psyp.12062\">https://doi.org/10.1111/psyp.12062</a>","ama":"Körner C, Braunstein V, Stangl M, Schlögl A, Neuper C, Ischebeck A. Sequential effects in continued visual search: Using fixation-related potentials to compare distractor processing before and after target detection. <i>Psychophysiology</i>. 2014;51(4):385-395. doi:<a href=\"https://doi.org/10.1111/psyp.12062\">10.1111/psyp.12062</a>"},"day":"11","article_processing_charge":"No","publication":"Psychophysiology","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","_id":"1890","external_id":{"isi":["000332585900010"]},"date_published":"2014-02-11T00:00:00Z","license":"https://creativecommons.org/licenses/by/4.0/","date_created":"2018-12-11T11:54:34Z","file_date_updated":"2020-07-14T12:45:20Z","publist_id":"5205","year":"2014","doi":"10.1111/psyp.12062","status":"public","date_updated":"2025-09-29T13:07:21Z","oa":1,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"file":[{"date_updated":"2020-07-14T12:45:20Z","checksum":"4255b6185e774acce1d99f8e195c564d","file_id":"5233","content_type":"application/pdf","date_created":"2018-12-12T10:16:44Z","relation":"main_file","file_size":543243,"creator":"system","access_level":"open_access","file_name":"IST-2016-442-v1+1_K-rner_et_al-2014-Psychophysiology.pdf"}],"title":"Sequential effects in continued visual search: Using fixation-related potentials to compare distractor processing before and after target detection","abstract":[{"lang":"eng","text":"To search for a target in a complex environment is an everyday behavior that ends with finding the target. When we search for two identical targets, however, we must continue the search after finding the first target and memorize its location. We used fixation-related potentials to investigate the neural correlates of different stages of the search, that is, before and after finding the first target. Having found the first target influenced subsequent distractor processing. Compared to distractor fixations before the first target fixation, a negative shift was observed for three subsequent distractor fixations. These results suggest that processing a target in continued search modulates the brain's response, either transiently by reflecting temporary working memory processes or permanently by reflecting working memory retention."}],"publisher":"Wiley-Blackwell"},{"ec_funded":1,"has_accepted_license":"1","issue":"11","corr_author":"1","article_number":"0113124","citation":{"ama":"Kim S. Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. <i>PLoS One</i>. 2014;9(11). doi:<a href=\"https://doi.org/10.1371/journal.pone.0113124\">10.1371/journal.pone.0113124</a>","apa":"Kim, S. (2014). Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0113124\">https://doi.org/10.1371/journal.pone.0113124</a>","short":"S. Kim, PLoS One 9 (2014).","ieee":"S. Kim, “Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus,” <i>PLoS One</i>, vol. 9, no. 11. Public Library of Science, 2014.","chicago":"Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons Facilitates OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of Rat Hippocampus.” <i>PLoS One</i>. Public Library of Science, 2014. <a href=\"https://doi.org/10.1371/journal.pone.0113124\">https://doi.org/10.1371/journal.pone.0113124</a>.","mla":"Kim, Sooyun. “Action Potential Modulation in CA1 Pyramidal Neuron Axons Facilitates OLM Interneuron Activation in Recurrent Inhibitory Microcircuits of Rat Hippocampus.” <i>PLoS One</i>, vol. 9, no. 11, 0113124, Public Library of Science, 2014, doi:<a href=\"https://doi.org/10.1371/journal.pone.0113124\">10.1371/journal.pone.0113124</a>.","ista":"Kim S. 2014. Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus. PLoS One. 9(11), 0113124."},"ddc":["570"],"intvolume":"         9","scopus_import":"1","volume":9,"month":"11","isi":1,"publication_status":"published","author":[{"id":"394AB1C8-F248-11E8-B48F-1D18A9856A87","first_name":"Sooyun","full_name":"Kim, Sooyun","last_name":"Kim"}],"department":[{"_id":"PeJo"}],"pubrep_id":"434","oa_version":"Published Version","language":[{"iso":"eng"}],"project":[{"_id":"25C0F108-B435-11E9-9278-68D0E5697425","name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons","grant_number":"268548","call_identifier":"FP7"}],"doi":"10.1371/journal.pone.0113124","date_updated":"2025-09-29T12:03:47Z","status":"public","oa":1,"tmp":{"image":"/images/cc_by_sa.png","short":"CC BY-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode","name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)"},"file":[{"file_id":"5107","content_type":"application/pdf","checksum":"85e4f4ea144f827272aaf376b2830564","date_updated":"2020-07-14T12:45:24Z","file_name":"IST-2016-434-v1+1_journal.pone.0113124.pdf","relation":"main_file","date_created":"2018-12-12T10:14:52Z","creator":"system","file_size":5179993,"access_level":"open_access"}],"publisher":"Public Library of Science","quality_controlled":"1","abstract":[{"lang":"eng","text":"Oriens-lacunosum moleculare (O-LM) interneurons in the CA1 region of the hippocampus play a key role in feedback inhibition and in the control of network activity. However, how these cells are efficiently activated in the network remains unclear. To address this question, I performed recordings from CA1 pyramidal neuron axons, the presynaptic fibers that provide feedback innervation of these interneurons. Two forms of axonal action potential (AP) modulation were identified. First, repetitive stimulation resulted in activity-dependent AP broadening. Broadening showed fast onset, with marked changes in AP shape following a single AP. Second, tonic depolarization in CA1 pyramidal neuron somata induced AP broadening in the axon, and depolarization-induced broadening summated with activity-dependent broadening. Outsideout patch recordings from CA1 pyramidal neuron axons revealed a high density of a-dendrotoxin (α-DTX)-sensitive, inactivating K+ channels, suggesting that K+ channel inactivation mechanistically contributes to AP broadening. To examine the functional consequences of axonal AP modulation for synaptic transmission, I performed paired recordings between synaptically connected CA1 pyramidal neurons and O-LM interneurons. CA1 pyramidal neuron-O-LM interneuron excitatory postsynaptic currents (EPSCs) showed facilitation during both repetitive stimulation and tonic depolarization of the presynaptic neuron. Both effects were mimicked and occluded by α-DTX, suggesting that they were mediated by K+ channel inactivation. Therefore, axonal AP modulation can greatly facilitate the activation of O-LM interneurons. In conclusion, modulation of AP shape in CA1 pyramidal neuron axons substantially enhances the efficacy of principal neuron-interneuron synapses, promoting the activation of O-LM interneurons in recurrent inhibitory microcircuits."}],"title":"Action potential modulation in CA1 pyramidal neuron axons facilitates OLM interneuron activation in recurrent inhibitory microcircuits of rat hippocampus","article_processing_charge":"No","day":"19","publication":"PLoS One","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_published":"2014-11-19T00:00:00Z","external_id":{"isi":["000345533200070"]},"_id":"2002","date_created":"2018-12-11T11:55:09Z","license":"https://creativecommons.org/licenses/by-sa/4.0/","file_date_updated":"2020-07-14T12:45:24Z","year":"2014","publist_id":"5074"},{"corr_author":"1","citation":{"ista":"Arai  itaru, Jonas PM. 2014. Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. eLife. 3.","mla":"Arai, itaru, and Peter M. Jonas. “Nanodomain Coupling Explains Ca^2+ Independence of Transmitter Release Time Course at a Fast Central Synapse.” <i>ELife</i>, vol. 3, eLife Sciences Publications, 2014, doi:<a href=\"https://doi.org/10.7554/eLife.04057\">10.7554/eLife.04057</a>.","chicago":"Arai, itaru, and Peter M Jonas. “Nanodomain Coupling Explains Ca^2+ Independence of Transmitter Release Time Course at a Fast Central Synapse.” <i>ELife</i>. eLife Sciences Publications, 2014. <a href=\"https://doi.org/10.7554/eLife.04057\">https://doi.org/10.7554/eLife.04057</a>.","ieee":"itaru Arai and P. M. Jonas, “Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse,” <i>eLife</i>, vol. 3. eLife Sciences Publications, 2014.","short":"itaru Arai, P.M. Jonas, ELife 3 (2014).","apa":"Arai,  itaru, &#38; Jonas, P. M. (2014). Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.04057\">https://doi.org/10.7554/eLife.04057</a>","ama":"Arai  itaru, Jonas PM. Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse. <i>eLife</i>. 2014;3. doi:<a href=\"https://doi.org/10.7554/eLife.04057\">10.7554/eLife.04057</a>"},"ec_funded":1,"has_accepted_license":"1","month":"12","volume":3,"publication_status":"published","isi":1,"department":[{"_id":"PeJo"}],"author":[{"first_name":"Itaru","id":"32A73F6C-F248-11E8-B48F-1D18A9856A87","last_name":"Arai","full_name":"Arai, Itaru"},{"full_name":"Jonas, Peter M","last_name":"Jonas","orcid":"0000-0001-5001-4804","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"ddc":["570"],"intvolume":"         3","scopus_import":"1","oa_version":"Submitted Version","language":[{"iso":"eng"}],"pubrep_id":"421","oa":1,"project":[{"call_identifier":"FWF","_id":"25C26B1E-B435-11E9-9278-68D0E5697425","name":"Mechanisms of transmitter release at GABAergic synapses","grant_number":"P24909-B24"},{"name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons","grant_number":"268548","_id":"25C0F108-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"}],"status":"public","date_updated":"2025-09-29T11:55:24Z","doi":"10.7554/eLife.04057","file":[{"file_size":2239563,"access_level":"open_access","creator":"system","date_created":"2018-12-12T10:14:41Z","relation":"main_file","file_name":"IST-2016-421-v1+1_e04057.full.pdf","date_updated":"2020-07-14T12:45:26Z","checksum":"c240f915450d4ebe8f95043a2a8c7b1a","file_id":"5094","content_type":"application/pdf"}],"publisher":"eLife Sciences Publications","title":"Nanodomain coupling explains Ca^2+ independence of transmitter release time course at a fast central synapse","quality_controlled":"1","abstract":[{"lang":"eng","text":"A puzzling property of synaptic transmission, originally established at the neuromuscular junction, is that the time course of transmitter release is independent of the extracellular Ca2+ concentration ([Ca2+]o), whereas the rate of release is highly [Ca2+]o-dependent. Here, we examine the time course of release at inhibitory basket cell-Purkinje cell synapses and show that it is independent of [Ca2+]o. Modeling of Ca2+-dependent transmitter release suggests that the invariant time course of release critically depends on tight coupling between Ca2+ channels and release sensors. Experiments with exogenous Ca2+ chelators reveal that channel-sensor coupling at basket cell-Purkinje cell synapses is very tight, with a mean distance of 10–20 nm. Thus, tight channel-sensor coupling provides a mechanistic explanation for the apparent [Ca2+]o independence of the time course of release."}],"publication":"eLife","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","article_processing_charge":"No","day":"09","file_date_updated":"2020-07-14T12:45:26Z","year":"2014","publist_id":"5041","date_published":"2014-12-09T00:00:00Z","_id":"2031","external_id":{"isi":["000346170300007"]},"date_created":"2018-12-11T11:55:19Z"},{"date_created":"2018-12-11T11:55:22Z","external_id":{"isi":["000341953300001"]},"_id":"2041","date_published":"2014-09-10T00:00:00Z","publist_id":"5010","year":"2014","file_date_updated":"2020-07-14T12:45:26Z","day":"10","article_processing_charge":"No","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"Frontiers in Neural Circuits","abstract":[{"text":"The hippocampus mediates several higher brain functions, such as learning, memory, and spatial coding. The input region of the hippocampus, the dentate gyrus, plays a critical role in these processes. Several lines of evidence suggest that the dentate gyrus acts as a preprocessor of incoming information, preparing it for subsequent processing in CA3. For example, the dentate gyrus converts input from the entorhinal cortex, where cells have multiple spatial fields, into the spatially more specific place cell activity characteristic of the CA3 region. Furthermore, the dentate gyrus is involved in pattern separation, transforming relatively similar input patterns into substantially different output patterns. Finally, the dentate gyrus produces a very sparse coding scheme in which only a very small fraction of neurons are active at any one time.","lang":"eng"}],"title":"Structure, function and plasticity of hippocampal dentate gyrus microcircuits","quality_controlled":"1","publisher":"Frontiers Research Foundation","file":[{"date_updated":"2020-07-14T12:45:26Z","content_type":"application/pdf","checksum":"3ca57b164045523f876407e9f13a9fb8","file_id":"5294","file_size":201110,"creator":"system","access_level":"open_access","date_created":"2018-12-12T10:17:38Z","relation":"main_file","file_name":"IST-2016-424-v1+1_fncir-08-00107.pdf"}],"status":"public","date_updated":"2025-09-29T11:52:44Z","doi":"10.3389/fncir.2014.00107","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"pubrep_id":"424","language":[{"iso":"eng"}],"oa_version":"Published Version","scopus_import":"1","intvolume":"         8","ddc":["570"],"author":[{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804"},{"last_name":"Lisman","full_name":"Lisman, John","first_name":"John"}],"department":[{"_id":"PeJo"}],"isi":1,"publication_status":"published","month":"09","volume":8,"has_accepted_license":"1","citation":{"ista":"Jonas PM, Lisman J. 2014. Structure, function and plasticity of hippocampal dentate gyrus microcircuits. Frontiers in Neural Circuits. 8, 2p.","mla":"Jonas, Peter M., and John Lisman. “Structure, Function and Plasticity of Hippocampal Dentate Gyrus Microcircuits.” <i>Frontiers in Neural Circuits</i>, vol. 8, 2p, Frontiers Research Foundation, 2014, doi:<a href=\"https://doi.org/10.3389/fncir.2014.00107\">10.3389/fncir.2014.00107</a>.","chicago":"Jonas, Peter M, and John Lisman. “Structure, Function and Plasticity of Hippocampal Dentate Gyrus Microcircuits.” <i>Frontiers in Neural Circuits</i>. Frontiers Research Foundation, 2014. <a href=\"https://doi.org/10.3389/fncir.2014.00107\">https://doi.org/10.3389/fncir.2014.00107</a>.","ieee":"P. M. Jonas and J. Lisman, “Structure, function and plasticity of hippocampal dentate gyrus microcircuits,” <i>Frontiers in Neural Circuits</i>, vol. 8. Frontiers Research Foundation, 2014.","short":"P.M. Jonas, J. Lisman, Frontiers in Neural Circuits 8 (2014).","apa":"Jonas, P. M., &#38; Lisman, J. (2014). Structure, function and plasticity of hippocampal dentate gyrus microcircuits. <i>Frontiers in Neural Circuits</i>. Frontiers Research Foundation. <a href=\"https://doi.org/10.3389/fncir.2014.00107\">https://doi.org/10.3389/fncir.2014.00107</a>","ama":"Jonas PM, Lisman J. Structure, function and plasticity of hippocampal dentate gyrus microcircuits. <i>Frontiers in Neural Circuits</i>. 2014;8. doi:<a href=\"https://doi.org/10.3389/fncir.2014.00107\">10.3389/fncir.2014.00107</a>"},"corr_author":"1","article_number":"2p"},{"status":"public","date_updated":"2025-09-29T11:48:03Z","doi":"10.1126/science.1255263","project":[{"_id":"25C26B1E-B435-11E9-9278-68D0E5697425","name":"Mechanisms of transmitter release at GABAergic synapses","grant_number":"P24909-B24","call_identifier":"FWF"},{"_id":"25C0F108-B435-11E9-9278-68D0E5697425","grant_number":"268548","name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons","call_identifier":"FP7"}],"oa":1,"file":[{"file_name":"IST-2017-821-v1+1_1255263JonasPVReviewTextR_Final.pdf","access_level":"open_access","file_size":215514,"creator":"system","relation":"main_file","date_created":"2018-12-12T10:16:00Z","content_type":"application/pdf","checksum":"a0036a589037d37e86364fa25cc0a82f","file_id":"5185","date_updated":"2020-07-14T12:45:27Z"},{"checksum":"e1f57d2713725449cb898fdcb8ef47b8","file_id":"5186","content_type":"application/pdf","date_updated":"2020-07-14T12:45:27Z","file_name":"IST-2017-821-v1+2_1255263JonasPVReviewFigures_Final.pdf","creator":"system","file_size":1732723,"access_level":"open_access","relation":"main_file","date_created":"2018-12-12T10:16:01Z"}],"title":"Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function","quality_controlled":"1","abstract":[{"text":"The success story of fast-spiking, parvalbumin-positive (PV+) GABAergic interneurons (GABA, γ-aminobutyric acid) in the mammalian central nervous system is noteworthy. In 1995, the properties of these interneurons were completely unknown. Twenty years later, thanks to the massive use of subcellular patch-clamp techniques, simultaneous multiple-cell recording, optogenetics, in vivo measurements, and computational approaches, our knowledge about PV+ interneurons became more extensive than for several types of pyramidal neurons. These findings have implications beyond the “small world” of basic research on GABAergic cells. For example, the results provide a first proof of principle that neuroscientists might be able to close the gaps between the molecular, cellular, network, and behavioral levels, representing one of the main challenges at the present time. Furthermore, the results may form the basis for PV+ interneurons as therapeutic targets for brain disease in the future. However, much needs to be learned about the basic function of these interneurons before clinical neuroscientists will be able to use PV+ interneurons for therapeutic purposes.","lang":"eng"}],"publisher":"American Association for the Advancement of Science","day":"01","article_processing_charge":"No","publication":"Science","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","external_id":{"isi":["000339651300036"]},"_id":"2062","date_published":"2014-08-01T00:00:00Z","date_created":"2018-12-11T11:55:29Z","file_date_updated":"2020-07-14T12:45:27Z","publist_id":"4984","year":"2014","ec_funded":1,"has_accepted_license":"1","issue":"6196","citation":{"chicago":"Hu, Hua, Jian Gan, and Peter M Jonas. “Fast-Spiking Parvalbumin^+ GABAergic Interneurons: From Cellular Design to Microcircuit Function.” <i>Science</i>. American Association for the Advancement of Science, 2014. <a href=\"https://doi.org/10.1126/science.1255263\">https://doi.org/10.1126/science.1255263</a>.","ieee":"H. Hu, J. Gan, and P. M. Jonas, “Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function,” <i>Science</i>, vol. 345, no. 6196. American Association for the Advancement of Science, 2014.","mla":"Hu, Hua, et al. “Fast-Spiking Parvalbumin^+ GABAergic Interneurons: From Cellular Design to Microcircuit Function.” <i>Science</i>, vol. 345, no. 6196, 1255263, American Association for the Advancement of Science, 2014, doi:<a href=\"https://doi.org/10.1126/science.1255263\">10.1126/science.1255263</a>.","ista":"Hu H, Gan J, Jonas PM. 2014. Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function. Science. 345(6196), 1255263.","ama":"Hu H, Gan J, Jonas PM. Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function. <i>Science</i>. 2014;345(6196). doi:<a href=\"https://doi.org/10.1126/science.1255263\">10.1126/science.1255263</a>","apa":"Hu, H., Gan, J., &#38; Jonas, P. M. (2014). Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to microcircuit function. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1255263\">https://doi.org/10.1126/science.1255263</a>","short":"H. Hu, J. Gan, P.M. Jonas, Science 345 (2014)."},"article_number":"1255263","corr_author":"1","scopus_import":"1","ddc":["570"],"intvolume":"       345","volume":345,"month":"08","author":[{"last_name":"Hu","full_name":"Hu, Hua","first_name":"Hua","id":"4AC0145C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jian","id":"3614E438-F248-11E8-B48F-1D18A9856A87","last_name":"Gan","full_name":"Gan, Jian"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M","last_name":"Jonas"}],"department":[{"_id":"PeJo"}],"isi":1,"publication_status":"published","pubrep_id":"821","oa_version":"Submitted Version","language":[{"iso":"eng"}]},{"year":"2013","file_date_updated":"2021-12-01T14:38:08Z","date_created":"2021-12-01T14:35:35Z","pmid":1,"_id":"10396","external_id":{"isi":["000497714000034"],"pmid":["24042795"]},"date_published":"2013-08-01T00:00:00Z","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Biomedical Engineering / Biomedizinische Technik","day":"01","article_processing_charge":"No","publication_identifier":{"issn":["0013-5585"],"eissn":["1862-278X"]},"title":"Stimfit: A fast visualization and analysis environment for cellular neurophysiology","abstract":[{"lang":"eng","text":"Stimfit is a free cross-platform software package for viewing and analyzing electrophysiological data. It supports most standard file types for cellular neurophysiology and other biomedical formats. Its analysis algorithms have been used and validated in several experimental laboratories. Its embedded Python scripting interface makes Stimfit highly extensible and customizable."}],"quality_controlled":"1","publisher":"De Gruyter","file":[{"date_created":"2021-12-01T14:38:08Z","relation":"main_file","access_level":"open_access","file_size":149825,"creator":"schloegl","file_name":"Schloegl_Abstract-BMT2013.pdf","date_updated":"2021-12-01T14:38:08Z","success":1,"content_type":"application/pdf","checksum":"cdfc5339b530a25d6079f7223f0b1f16","file_id":"10397"}],"article_type":"original","oa":1,"date_updated":"2025-09-30T07:31:23Z","doi":"10.1515/bmt-2013-4181","status":"public","keyword":["biomedical engineering","data analysis","free software"],"language":[{"iso":"eng"}],"oa_version":"Submitted Version","author":[{"first_name":"Alois","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","last_name":"Schlögl","full_name":"Schlögl, Alois","orcid":"0000-0002-5621-8100"},{"orcid":"0000-0001-5001-4804","full_name":"Jonas, Peter M","last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"},{"first_name":"C.","last_name":"Schmidt-Hieber","full_name":"Schmidt-Hieber, C."},{"full_name":"Guzman, S. J.","last_name":"Guzman","first_name":"S. J."}],"conference":{"name":"BMT: Biomedizinische Technik ","end_date":"2013-09-21","location":"Graz, Austria","start_date":"2013-09-19"},"department":[{"_id":"PeJo"}],"publication_status":"published","isi":1,"volume":58,"month":"08","intvolume":"        58","ddc":["005","610"],"citation":{"short":"A. Schlögl, P.M. Jonas, C. Schmidt-Hieber, S.J. Guzman, Biomedical Engineering / Biomedizinische Technik 58 (2013).","ama":"Schlögl A, Jonas PM, Schmidt-Hieber C, Guzman SJ. Stimfit: A fast visualization and analysis environment for cellular neurophysiology. <i>Biomedical Engineering / Biomedizinische Technik</i>. 2013;58(SI-1-Track-G). doi:<a href=\"https://doi.org/10.1515/bmt-2013-4181\">10.1515/bmt-2013-4181</a>","apa":"Schlögl, A., Jonas, P. M., Schmidt-Hieber, C., &#38; Guzman, S. J. (2013). Stimfit: A fast visualization and analysis environment for cellular neurophysiology. <i>Biomedical Engineering / Biomedizinische Technik</i>. Graz, Austria: De Gruyter. <a href=\"https://doi.org/10.1515/bmt-2013-4181\">https://doi.org/10.1515/bmt-2013-4181</a>","ista":"Schlögl A, Jonas PM, Schmidt-Hieber C, Guzman SJ. 2013. Stimfit: A fast visualization and analysis environment for cellular neurophysiology. Biomedical Engineering / Biomedizinische Technik. 58(SI-1-Track-G), 000010151520134181.","chicago":"Schlögl, Alois, Peter M Jonas, C. Schmidt-Hieber, and S. J. Guzman. “Stimfit: A Fast Visualization and Analysis Environment for Cellular Neurophysiology.” <i>Biomedical Engineering / Biomedizinische Technik</i>. De Gruyter, 2013. <a href=\"https://doi.org/10.1515/bmt-2013-4181\">https://doi.org/10.1515/bmt-2013-4181</a>.","ieee":"A. Schlögl, P. M. Jonas, C. Schmidt-Hieber, and S. J. Guzman, “Stimfit: A fast visualization and analysis environment for cellular neurophysiology,” <i>Biomedical Engineering / Biomedizinische Technik</i>, vol. 58, no. SI-1-Track-G. De Gruyter, 2013.","mla":"Schlögl, Alois, et al. “Stimfit: A Fast Visualization and Analysis Environment for Cellular Neurophysiology.” <i>Biomedical Engineering / Biomedizinische Technik</i>, vol. 58, no. SI-1-Track-G, 000010151520134181, De Gruyter, 2013, doi:<a href=\"https://doi.org/10.1515/bmt-2013-4181\">10.1515/bmt-2013-4181</a>."},"corr_author":"1","article_number":"000010151520134181","issue":"SI-1-Track-G","has_accepted_license":"1"},{"publisher":"Institute of Science and Technology Austria","title":"Active properties of hippocampal CA3 pyramidal neuron dendrites","abstract":[{"lang":"eng","text":"CA3 pyramidal neurons are important for memory formation and pattern completion in the hippocampal network. These neurons receive multiple excitatory inputs from numerous sources. Therefore, the rules of spatiotemporal integration of multiple synaptic inputs and propagation of action potentials are important to understand how CA3 neurons contribute to higher brain functions at cellular level. By using confocally targeted patch-clamp recording techniques, we investigated the biophysical properties of rat CA3 pyramidal neuron dendrites. We found two distinct dendritic domains critical for action potential initiation and propagation: In the proximal domain, action potentials initiated in the axon backpropagate actively with large amplitude and fast time course. In the distal domain, Na+-channel mediated dendritic spikes are efficiently evoked by local dendritic depolarization or waveforms mimicking synaptic events. These findings can be explained by a high Na+-to-K+ conductance density ratio of CA3 pyramidal neuron dendrites. The results challenge the prevailing view that proximal mossy fiber inputs activate CA3 pyramidal neurons more efficiently than distal perforant inputs by showing that the distal synapses trigger a different form of activity represented by dendritic spikes. The high probability of dendritic spike initiation in the distal area may enhance the computational power of CA3 pyramidal neurons in the hippocampal network.  "}],"alternative_title":["ISTA Thesis"],"degree_awarded":"PhD","related_material":{"record":[{"status":"public","id":"3258","relation":"part_of_dissertation"}]},"corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"citation":{"ista":"Kim S. 2012. Active properties of hippocampal CA3 pyramidal neuron dendrites. Institute of Science and Technology Austria.","mla":"Kim, Sooyun. <i>Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites</i>. Institute of Science and Technology Austria, 2012.","ieee":"S. Kim, “Active properties of hippocampal CA3 pyramidal neuron dendrites,” Institute of Science and Technology Austria, 2012.","chicago":"Kim, Sooyun. “Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites.” Institute of Science and Technology Austria, 2012.","short":"S. Kim, Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites, Institute of Science and Technology Austria, 2012.","apa":"Kim, S. (2012). <i>Active properties of hippocampal CA3 pyramidal neuron dendrites</i>. Institute of Science and Technology Austria.","ama":"Kim S. Active properties of hippocampal CA3 pyramidal neuron dendrites. 2012."},"supervisor":[{"last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"status":"public","date_updated":"2026-06-18T18:41:53Z","OA_place":"publisher","date_created":"2018-12-11T12:00:35Z","date_published":"2012-06-01T00:00:00Z","_id":"2964","year":"2012","language":[{"iso":"eng"}],"publist_id":"3755","page":"65","oa_version":"None","article_processing_charge":"No","day":"01","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","type":"dissertation","publication_status":"published","department":[{"_id":"PeJo"},{"_id":"GradSch"}],"author":[{"full_name":"Kim, Sooyun","last_name":"Kim","first_name":"Sooyun","id":"394AB1C8-F248-11E8-B48F-1D18A9856A87"}],"month":"06"},{"day":"10","article_processing_charge":"No","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"Journal of Neuroscience","pmid":1,"date_created":"2018-12-11T12:00:36Z","external_id":{"pmid":["23055500"],"isi":["000309963700030"]},"_id":"2969","date_published":"2012-10-10T00:00:00Z","publist_id":"3744","year":"2012","doi":"10.1523/JNEUROSCI.6104-11.2012","status":"public","date_updated":"2025-09-30T08:03:27Z","project":[{"grant_number":"SFB-TR3-TP10B","name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen","_id":"25BDE9A4-B435-11E9-9278-68D0E5697425"}],"oa":1,"quality_controlled":"1","title":"Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling","abstract":[{"lang":"eng","text":"The coupling between presynaptic Ca^(2+) channels and Ca^(2+) sensors of exocytosis is a key determinant of synaptic transmission. Evoked release from parvalbumin (PV)-expressing interneurons is triggered by nanodomain coupling of P/Q-type Ca^(2+) channels, whereas release from cholecystokinin (CCK)-containing interneurons is generated by microdomain coupling of N-type channels. Nanodomain coupling has several functional advantages, including speed and efficacy of transmission. One potential disadvantage is that stochastic\r\nopening of presynaptic Ca^(2+) channels may trigger spontaneous transmitter release. We addressed this possibility in rat hippocampal\r\ngranule cells, which receive converging inputs from different inhibitory sources. Both reduction of extracellular Ca^(2+) concentration and the unselective Ca^(2+) channel blocker Cd^(2+) reduced the frequency of miniature IPSCs (mIPSCs) in granule cells by ~50%, suggesting that the opening of presynaptic Ca^(2+) channels contributes to spontaneous release. Application of the selective P/Q-type Ca^(2+) channel blocker\r\nω-agatoxin IVa had no detectable effects, whereas both the N-type blocker ω-conotoxin GVIa and the L-type blocker nimodipine reduced\r\nmIPSC frequency. Furthermore, both the fast Ca^(2+) chelator BAPTA-AM and the slow chelator EGTA-AM reduced the mIPSC frequency,\r\nsuggesting that Ca^(2+)-dependent spontaneous release is triggered by microdomain rather than nanodomain coupling. The CB_(1) receptor\r\nagonist WIN 55212-2 also decreased spontaneous release; this effect was occluded by prior application of ω-conotoxin GVIa, suggesting that a major fraction of Ca^(2+)-dependent spontaneous release was generated at the terminals of CCK-expressing interneurons. Tonic inhibition generated by spontaneous opening of presynaptic N- and L-type Ca^(2+) channels may be important for hippocampal information processing.\r\n"}],"publisher":"Society for Neuroscience","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632771/"}],"scopus_import":"1","intvolume":"        32","acknowledgement":"This work was supported by grants from the Deutsche Forschungsgemeinschaft (TR 3/B10, Leibniz program, GSC-4 Spemann Graduate School) and the European Union (European Research Council Advanced Grant).","department":[{"_id":"PeJo"}],"author":[{"last_name":"Goswami","full_name":"Goswami, Sarit","first_name":"Sarit","id":"3A578F32-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Iancu","last_name":"Bucurenciu","full_name":"Bucurenciu, Iancu"},{"orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"publication_status":"published","isi":1,"month":"10","volume":32,"language":[{"iso":"eng"}],"oa_version":"Submitted Version","page":"14294 - 14304","citation":{"short":"S. Goswami, I. Bucurenciu, P.M. Jonas, Journal of Neuroscience 32 (2012) 14294–14304.","ama":"Goswami S, Bucurenciu I, Jonas PM. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. <i>Journal of Neuroscience</i>. 2012;32(41):14294-14304. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">10.1523/JNEUROSCI.6104-11.2012</a>","apa":"Goswami, S., Bucurenciu, I., &#38; Jonas, P. M. (2012). Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">https://doi.org/10.1523/JNEUROSCI.6104-11.2012</a>","ista":"Goswami S, Bucurenciu I, Jonas PM. 2012. Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. Journal of Neuroscience. 32(41), 14294–14304.","chicago":"Goswami, Sarit, Iancu Bucurenciu, and Peter M Jonas. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2012. <a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">https://doi.org/10.1523/JNEUROSCI.6104-11.2012</a>.","ieee":"S. Goswami, I. Bucurenciu, and P. M. Jonas, “Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling,” <i>Journal of Neuroscience</i>, vol. 32, no. 41. Society for Neuroscience, pp. 14294–14304, 2012.","mla":"Goswami, Sarit, et al. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” <i>Journal of Neuroscience</i>, vol. 32, no. 41, Society for Neuroscience, 2012, pp. 14294–304, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6104-11.2012\">10.1523/JNEUROSCI.6104-11.2012</a>."},"corr_author":"1","issue":"41"},{"file":[{"date_updated":"2020-07-14T12:46:35Z","file_id":"5356","content_type":"application/pdf","checksum":"195238221c4b0b0f4035f6f6c16ea17c","relation":"main_file","date_created":"2018-12-12T10:18:34Z","access_level":"open_access","creator":"system","file_size":2693701,"file_name":"IST-2018-945-v1+1_2012_Schloegl_Review_of.pdf"}],"publisher":"Frontiers Research Foundation","title":"Review of the BCI competition IV","quality_controlled":"1","abstract":[{"lang":"eng","text":"The BCI competition IV stands in the tradition of prior BCI competitions that aim to provide high quality neuroscientific data for open access to the scientific community. As experienced already in prior competitions not only scientists from the narrow field of BCI compete, but scholars with a broad variety of backgrounds and nationalities. They include high specialists as well as students.The goals of all BCI competitions have always been to challenge with respect to novel paradigms and complex data. We report on the following challenges: (1) asynchronous data, (2) synthetic, (3) multi-class continuous data, (4) sessionto-session transfer, (5) directionally modulated MEG, (6) finger movements recorded by ECoG. As after past competitions, our hope is that winning entries may enhance the analysis methods of future BCIs."}],"oa":1,"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"date_updated":"2025-09-30T08:35:59Z","doi":"10.3389/fnins.2012.00055","status":"public","file_date_updated":"2020-07-14T12:46:35Z","year":"2012","publist_id":"7327","date_published":"2012-07-13T00:00:00Z","_id":"493","external_id":{"isi":["000209165300066"]},"date_created":"2018-12-11T11:46:46Z","publication":"Frontiers in Neuroscience","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","article_processing_charge":"No","day":"13","article_number":"55","citation":{"ista":"Tangermann M, Müller K, Aertsen A, Birbaumer N, Braun C, Brunner C, Leeb R, Mehring C, Miller K, Müller Putz G, Nolte G, Pfurtscheller G, Preissl H, Schalk G, Schlögl A, Vidaurre C, Waldert S, Blankertz B. 2012. Review of the BCI competition IV. Frontiers in Neuroscience. 6, 55.","ieee":"M. Tangermann <i>et al.</i>, “Review of the BCI competition IV,” <i>Frontiers in Neuroscience</i>, vol. 6. Frontiers Research Foundation, 2012.","chicago":"Tangermann, Michael, Klaus Müller, Ad Aertsen, Niels Birbaumer, Christoph Braun, Clemens Brunner, Robert Leeb, et al. “Review of the BCI Competition IV.” <i>Frontiers in Neuroscience</i>. Frontiers Research Foundation, 2012. <a href=\"https://doi.org/10.3389/fnins.2012.00055\">https://doi.org/10.3389/fnins.2012.00055</a>.","mla":"Tangermann, Michael, et al. “Review of the BCI Competition IV.” <i>Frontiers in Neuroscience</i>, vol. 6, 55, Frontiers Research Foundation, 2012, doi:<a href=\"https://doi.org/10.3389/fnins.2012.00055\">10.3389/fnins.2012.00055</a>.","short":"M. Tangermann, K. Müller, A. Aertsen, N. Birbaumer, C. Braun, C. Brunner, R. Leeb, C. Mehring, K. Miller, G. Müller Putz, G. Nolte, G. Pfurtscheller, H. Preissl, G. Schalk, A. Schlögl, C. Vidaurre, S. Waldert, B. Blankertz, Frontiers in Neuroscience 6 (2012).","ama":"Tangermann M, Müller K, Aertsen A, et al. Review of the BCI competition IV. <i>Frontiers in Neuroscience</i>. 2012;6. doi:<a href=\"https://doi.org/10.3389/fnins.2012.00055\">10.3389/fnins.2012.00055</a>","apa":"Tangermann, M., Müller, K., Aertsen, A., Birbaumer, N., Braun, C., Brunner, C., … Blankertz, B. (2012). Review of the BCI competition IV. <i>Frontiers in Neuroscience</i>. Frontiers Research Foundation. <a href=\"https://doi.org/10.3389/fnins.2012.00055\">https://doi.org/10.3389/fnins.2012.00055</a>"},"has_accepted_license":"1","oa_version":"Published Version","language":[{"iso":"eng"}],"pubrep_id":"945","month":"07","volume":6,"isi":1,"publication_status":"published","department":[{"_id":"ScienComp"},{"_id":"PeJo"}],"author":[{"full_name":"Tangermann, Michael","last_name":"Tangermann","first_name":"Michael"},{"full_name":"Müller, Klaus","last_name":"Müller","first_name":"Klaus"},{"first_name":"Ad","full_name":"Aertsen, Ad","last_name":"Aertsen"},{"first_name":"Niels","last_name":"Birbaumer","full_name":"Birbaumer, Niels"},{"last_name":"Braun","full_name":"Braun, Christoph","first_name":"Christoph"},{"full_name":"Brunner, Clemens","last_name":"Brunner","first_name":"Clemens"},{"first_name":"Robert","last_name":"Leeb","full_name":"Leeb, Robert"},{"full_name":"Mehring, Carsten","last_name":"Mehring","first_name":"Carsten"},{"full_name":"Miller, Kai","last_name":"Miller","first_name":"Kai"},{"full_name":"Müller Putz, Gernot","last_name":"Müller Putz","first_name":"Gernot"},{"first_name":"Guido","full_name":"Nolte, Guido","last_name":"Nolte"},{"full_name":"Pfurtscheller, Gert","last_name":"Pfurtscheller","first_name":"Gert"},{"first_name":"Hubert","last_name":"Preissl","full_name":"Preissl, Hubert"},{"full_name":"Schalk, Gerwin","last_name":"Schalk","first_name":"Gerwin"},{"id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","first_name":"Alois","orcid":"0000-0002-5621-8100","last_name":"Schlögl","full_name":"Schlögl, Alois"},{"full_name":"Vidaurre, Carmen","last_name":"Vidaurre","first_name":"Carmen"},{"last_name":"Waldert","full_name":"Waldert, Stephan","first_name":"Stephan"},{"full_name":"Blankertz, Benjamin","last_name":"Blankertz","first_name":"Benjamin"}],"acknowledgement":"The studies were in part or completely supported by the Bundesministerium für Bildung und Forschung (BMBF), Fkz 01IB001A, 01GQ0850, by the German Science Foundation (DFG, contract MU 987/3-2), by the European ICT Programme Projects FP7-224631 and 216886, the World Class University Program through the National Research Foundation of Korea funded by the Ministry of Education, Science, and Technology (Grant R31-10008), the US Army Research Office [W911NF-08-1-0216 (Gerwin Schalk) and W911NF-07-1-0415 (Gerwin Schalk)] and the NIH [EB006356 (Gerwin Schalk) and EB000856 (Gerwin Schalk), the WIN-Kolleg of the Heidelberg Academy of Sciences and Humanities, German Federal Ministry of Education and Research grants 01GQ0420, 01GQ0761, 01GQ0762, and 01GQ0830, German Research Foundation grants 550/B5 and C6, and by a scholarship from the German National Academic Foundation. This paper only reflects the authors’ views and funding agencies are not liable for any use that may be made of the information contained herein.\r\n","intvolume":"         6","ddc":["004"],"scopus_import":"1"},{"citation":{"chicago":"Williams, Courtney, Wenyan Chen, Chia Lee, Daniel Yaeger, Nicholas Vyleta, and Stephen Smith. “Coactivation of Multiple Tightly Coupled Calcium Channels Triggers Spontaneous Release of GABA.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nn.3162\">https://doi.org/10.1038/nn.3162</a>.","ieee":"C. Williams, W. Chen, C. Lee, D. Yaeger, N. Vyleta, and S. Smith, “Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA,” <i>Nature Neuroscience</i>, vol. 15, no. 9. Nature Publishing Group, pp. 1195–1197, 2012.","mla":"Williams, Courtney, et al. “Coactivation of Multiple Tightly Coupled Calcium Channels Triggers Spontaneous Release of GABA.” <i>Nature Neuroscience</i>, vol. 15, no. 9, Nature Publishing Group, 2012, pp. 1195–97, doi:<a href=\"https://doi.org/10.1038/nn.3162\">10.1038/nn.3162</a>.","ista":"Williams C, Chen W, Lee C, Yaeger D, Vyleta N, Smith S. 2012. Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA. Nature Neuroscience. 15(9), 1195–1197.","ama":"Williams C, Chen W, Lee C, Yaeger D, Vyleta N, Smith S. Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA. <i>Nature Neuroscience</i>. 2012;15(9):1195-1197. doi:<a href=\"https://doi.org/10.1038/nn.3162\">10.1038/nn.3162</a>","apa":"Williams, C., Chen, W., Lee, C., Yaeger, D., Vyleta, N., &#38; Smith, S. (2012). Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.3162\">https://doi.org/10.1038/nn.3162</a>","short":"C. Williams, W. Chen, C. Lee, D. Yaeger, N. Vyleta, S. Smith, Nature Neuroscience 15 (2012) 1195–1197."},"issue":"9","language":[{"iso":"eng"}],"page":"1195 - 1197","oa_version":"Submitted Version","isi":1,"publication_status":"published","department":[{"_id":"PeJo"}],"author":[{"last_name":"Williams","full_name":"Williams, Courtney","first_name":"Courtney"},{"full_name":"Chen, Wenyan","last_name":"Chen","first_name":"Wenyan"},{"full_name":"Lee, Chia","last_name":"Lee","first_name":"Chia"},{"first_name":"Daniel","full_name":"Yaeger, Daniel","last_name":"Yaeger"},{"full_name":"Vyleta, Nicholas","last_name":"Vyleta","first_name":"Nicholas","id":"36C4978E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Stephen","full_name":"Smith, Stephen","last_name":"Smith"}],"volume":15,"month":"09","intvolume":"        15","scopus_import":"1","acknowledgement":"The work was supported by the US National Institutes of Health (DA027110 and GM097433) and OCTRI. C.W. and N.P.V. were supported by a grant from the National Heart, Lung, and Blood Institute (T32HL033808).\r\nWe thank M. Andresen and K. Khodakhah for helpful comments. ","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431448/","open_access":"1"}],"publisher":"Nature Publishing Group","abstract":[{"text":"Voltage-activated Ca(2+) channels (VACCs) mediate Ca(2+) influx to trigger action potential-evoked neurotransmitter release, but the mechanism by which Ca(2+) regulates spontaneous transmission is unclear. We found that VACCs are the major physiological triggers for spontaneous release at mouse neocortical inhibitory synapses. Moreover, despite the absence of a synchronizing action potential, we found that spontaneous fusion of a GABA-containing vesicle required the activation of multiple tightly coupled VACCs of variable type.","lang":"eng"}],"title":"Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA","quality_controlled":"1","oa":1,"date_updated":"2025-09-30T07:59:27Z","status":"public","doi":"10.1038/nn.3162","year":"2012","publist_id":"3578","pmid":1,"date_created":"2018-12-11T12:01:30Z","date_published":"2012-09-01T00:00:00Z","_id":"3121","external_id":{"isi":["000308072600008"],"pmid":["22842148"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"Nature Neuroscience","article_processing_charge":"No","day":"01"},{"date_updated":"2026-06-18T18:41:54Z","status":"public","doi":"10.1038/nn.3060","project":[{"_id":"25BDE9A4-B435-11E9-9278-68D0E5697425","grant_number":"SFB-TR3-TP10B","name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen"}],"oa":1,"article_type":"original","title":"Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons","quality_controlled":"1","abstract":[{"lang":"eng","text":"CA3 pyramidal neurons are important for memory formation and pattern completion in the hippocampal network. It is generally thought that proximal synapses from the mossy fibers activate these neurons most efficiently, whereas distal inputs from the perforant path have a weaker modulatory influence. We used confocally targeted patch-clamp recording from dendrites and axons to map the activation of rat CA3 pyramidal neurons at the subcellular level. Our results reveal two distinct dendritic domains. In the proximal domain, action potentials initiated in the axon backpropagate actively with large amplitude and fast time course. In the distal domain, Na+ channel–mediated dendritic spikes are efficiently initiated by waveforms mimicking synaptic events. CA3 pyramidal neuron dendrites showed a high Na+-to-K+ conductance density ratio, providing ideal conditions for active backpropagation and dendritic spike initiation. Dendritic spikes may enhance the computational power of CA3 pyramidal neurons in the hippocampal network."}],"publisher":"Nature Publishing Group","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617474/","open_access":"1"}],"publication_identifier":{"issn":["1546-1726"]},"day":"01","article_processing_charge":"No","publication":"Nature Neuroscience","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","external_id":{"isi":["000302114500020"],"pmid":["22388958"]},"_id":"3258","date_published":"2012-04-01T00:00:00Z","date_created":"2018-12-11T12:02:18Z","pmid":1,"publist_id":"3390","year":"2012","related_material":{"record":[{"relation":"dissertation_contains","id":"2964","status":"public"}]},"issue":"4","citation":{"ista":"Kim S, Guzmán J, Hu H, Jonas PM. 2012. Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. Nature Neuroscience. 15(4), 600–606.","ieee":"S. Kim, J. Guzmán, H. Hu, and P. M. Jonas, “Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons,” <i>Nature Neuroscience</i>, vol. 15, no. 4. Nature Publishing Group, pp. 600–606, 2012.","chicago":"Kim, Sooyun, José Guzmán, Hua Hu, and Peter M Jonas. “Active Dendrites Support Efficient Initiation of Dendritic Spikes in Hippocampal CA3 Pyramidal Neurons.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nn.3060\">https://doi.org/10.1038/nn.3060</a>.","mla":"Kim, Sooyun, et al. “Active Dendrites Support Efficient Initiation of Dendritic Spikes in Hippocampal CA3 Pyramidal Neurons.” <i>Nature Neuroscience</i>, vol. 15, no. 4, Nature Publishing Group, 2012, pp. 600–06, doi:<a href=\"https://doi.org/10.1038/nn.3060\">10.1038/nn.3060</a>.","short":"S. Kim, J. Guzmán, H. Hu, P.M. Jonas, Nature Neuroscience 15 (2012) 600–606.","ama":"Kim S, Guzmán J, Hu H, Jonas PM. Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. <i>Nature Neuroscience</i>. 2012;15(4):600-606. doi:<a href=\"https://doi.org/10.1038/nn.3060\">10.1038/nn.3060</a>","apa":"Kim, S., Guzmán, J., Hu, H., &#38; Jonas, P. M. (2012). Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.3060\">https://doi.org/10.1038/nn.3060</a>"},"corr_author":"1","acknowledgement":"This work was supported by the Deutsche Forschungsgemeinschaft (TR 3/B10) and the European Union (European Research Council Advanced grant to P.J.).","scopus_import":"1","intvolume":"        15","ddc":["570"],"volume":15,"month":"04","department":[{"_id":"PeJo"}],"author":[{"first_name":"Sooyun","id":"394AB1C8-F248-11E8-B48F-1D18A9856A87","full_name":"Kim, Sooyun","last_name":"Kim"},{"first_name":"José","id":"30CC5506-F248-11E8-B48F-1D18A9856A87","full_name":"Guzmán, José","last_name":"Guzmán","orcid":"0000-0003-2209-5242"},{"full_name":"Hu, Hua","last_name":"Hu","id":"4AC0145C-F248-11E8-B48F-1D18A9856A87","first_name":"Hua"},{"first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M"}],"publication_status":"published","isi":1,"oa_version":"Published Version","page":"600 - 606","language":[{"iso":"eng"}]},{"has_accepted_license":"1","corr_author":"1","citation":{"ama":"Eggermann E, Bucurenciu I, Goswami S, Jonas PM. Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses. <i>Nature Reviews Neuroscience</i>. 2012;13(1):7-21. doi:<a href=\"https://doi.org/10.1038/nrn3125\">10.1038/nrn3125</a>","apa":"Eggermann, E., Bucurenciu, I., Goswami, S., &#38; Jonas, P. M. (2012). Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses. <i>Nature Reviews Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nrn3125\">https://doi.org/10.1038/nrn3125</a>","short":"E. Eggermann, I. Bucurenciu, S. Goswami, P.M. Jonas, Nature Reviews Neuroscience 13 (2012) 7–21.","ieee":"E. Eggermann, I. Bucurenciu, S. Goswami, and P. M. Jonas, “Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses,” <i>Nature Reviews Neuroscience</i>, vol. 13, no. 1. Nature Publishing Group, pp. 7–21, 2012.","chicago":"Eggermann, Emmanuel, Iancu Bucurenciu, Sarit Goswami, and Peter M Jonas. “Nanodomain Coupling between Ca(2+) Channels and Sensors of Exocytosis at Fast Mammalian Synapses.” <i>Nature Reviews Neuroscience</i>. Nature Publishing Group, 2012. <a href=\"https://doi.org/10.1038/nrn3125\">https://doi.org/10.1038/nrn3125</a>.","mla":"Eggermann, Emmanuel, et al. “Nanodomain Coupling between Ca(2+) Channels and Sensors of Exocytosis at Fast Mammalian Synapses.” <i>Nature Reviews Neuroscience</i>, vol. 13, no. 1, Nature Publishing Group, 2012, pp. 7–21, doi:<a href=\"https://doi.org/10.1038/nrn3125\">10.1038/nrn3125</a>.","ista":"Eggermann E, Bucurenciu I, Goswami S, Jonas PM. 2012. Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses. Nature Reviews Neuroscience. 13(1), 7–21."},"issue":"1","ddc":["570"],"intvolume":"        13","scopus_import":"1","acknowledgement":"Work of the authors was funded by grants of the Deutsche Forschungsgemeinschaft to P.J. (grants SFB 780/A5, TR 3/B10 and the Leibniz programme), a European Research Council Advanced grant to P.J. and a Swiss National Foundation fellowship to E.E.\r\nWe thank D. Tsien and E. Neher for their comments on this Review, J. Guzmán and A. Pernía-Andrade for reading earlier versions and E. Kramberger for perfect editorial support. We apologize that owing to space constraints, not all relevant papers could be cited.\r\n","publication_status":"published","isi":1,"author":[{"first_name":"Emmanuel","id":"34DACA34-E9AE-11E9-849C-D35BD8ADC20C","last_name":"Eggermann","full_name":"Eggermann, Emmanuel"},{"first_name":"Iancu","id":"4BD1D872-E9AE-11E9-9EE9-8BF4597A9E2A","full_name":"Bucurenciu, Iancu","last_name":"Bucurenciu"},{"id":"3A578F32-F248-11E8-B48F-1D18A9856A87","first_name":"Sarit","last_name":"Goswami","full_name":"Goswami, Sarit"},{"last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"}],"department":[{"_id":"PeJo"}],"month":"01","volume":13,"pubrep_id":"820","language":[{"iso":"eng"}],"page":"7 - 21","oa_version":"Submitted Version","project":[{"_id":"25BC64A8-B435-11E9-9278-68D0E5697425","grant_number":"JO_780/A5","name":"Synaptic Mechanisms of Neuronal Network Function"},{"_id":"25BDE9A4-B435-11E9-9278-68D0E5697425","grant_number":"SFB-TR3-TP10B","name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen"}],"date_updated":"2025-09-30T07:34:43Z","status":"public","doi":"10.1038/nrn3125","oa":1,"publisher":"Nature Publishing Group","abstract":[{"text":"The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors that trigger exocytosis of neurotransmitter-containing vesicles is a key determinant of the signalling properties of synapses in the nervous system. Recent functional analysis indicates that in some fast central synapses, transmitter release is triggered by a small number of Ca2+ channels that are coupled to Ca2+ sensors at the nanometre scale. Molecular analysis suggests that this tight coupling is generated by protein–protein interactions involving Ca2+ channels, Ca2+ sensors and various other synaptic proteins. Nanodomain coupling has several functional advantages, as it increases the efficacy, speed and energy efficiency of synaptic transmission.","lang":"eng"}],"title":"Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses","quality_controlled":"1","file":[{"checksum":"4c1c86b2f6e4e1562f5bb800b457ea9f","content_type":"application/pdf","file_id":"4931","date_updated":"2020-07-14T12:46:07Z","file_name":"IST-2017-820-v1+1_17463_3_art_file_109404_ltmxbw.pdf","date_created":"2018-12-12T10:12:13Z","relation":"main_file","file_size":314246,"creator":"system","access_level":"open_access"},{"file_id":"4932","checksum":"bceb2efdd49d115f4dde8486bc1be3f2","content_type":"application/pdf","date_updated":"2020-07-14T12:46:07Z","file_name":"IST-2017-820-v1+2_17463_3_figure_109402_ltmwlp.pdf","date_created":"2018-12-12T10:12:14Z","relation":"main_file","creator":"system","file_size":1840216,"access_level":"open_access"}],"article_processing_charge":"No","day":"01","type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Nature Reviews Neuroscience","date_created":"2018-12-11T12:02:38Z","date_published":"2012-01-01T00:00:00Z","_id":"3317","external_id":{"isi":["000298323200008"]},"year":"2012","publist_id":"3322","file_date_updated":"2020-07-14T12:46:07Z"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","publication":"Biophysical Journal","article_processing_charge":"No","day":"03","year":"2012","publist_id":"3774","pmid":1,"date_created":"2018-12-11T12:00:32Z","date_published":"2012-10-03T00:00:00Z","_id":"2954","external_id":{"isi":["000309571400005"],"pmid":["23062335"]},"oa":1,"project":[{"_id":"25BDE9A4-B435-11E9-9278-68D0E5697425","name":"Glutamaterge synaptische Übertragung und Plastizität in hippocampalen Mikroschaltkreisen","grant_number":"SFB-TR3-TP10B"}],"doi":"10.1016/j.bpj.2012.08.039","status":"public","date_updated":"2026-07-06T12:32:51Z","main_file_link":[{"open_access":"1","url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471482/"}],"publisher":"Biophysical Society","abstract":[{"text":"Spontaneous postsynaptic currents (PSCs) provide key information about the mechanisms of synaptic transmission and the activity modes of neuronal networks. However, detecting spontaneous PSCs in vitro and in vivo has been challenging, because of the small amplitude, the variable kinetics, and the undefined time of generation of these events. Here, we describe a, to our knowledge, new method for detecting spontaneous synaptic events by deconvolution, using a template that approximates the average time course of spontaneous PSCs. A recorded PSC trace is deconvolved from the template, resulting in a series of delta-like functions. The maxima of these delta-like events are reliably detected, revealing the precise onset times of the spontaneous PSCs. Among all detection methods, the deconvolution-based method has a unique temporal resolution, allowing the detection of individual events in high-frequency bursts. Furthermore, the deconvolution-based method has a high amplitude resolution, because deconvolution can substantially increase the signal/noise ratio. When tested against previously published methods using experimental data, the deconvolution-based method was superior for spontaneous PSCs recorded in vivo. Using the high-resolution deconvolution-based detection algorithm, we show that the frequency of spontaneous excitatory postsynaptic currents in dentate gyrus granule cells is 4.5 times higher in vivo than in vitro.","lang":"eng"}],"quality_controlled":"1","title":"A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo","isi":1,"publication_status":"published","author":[{"last_name":"Pernia-Andrade","full_name":"Pernia-Andrade, Alejandro","first_name":"Alejandro","id":"36963E98-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Goswami","full_name":"Goswami, Sarit","id":"3A578F32-F248-11E8-B48F-1D18A9856A87","first_name":"Sarit"},{"first_name":"Yvonne","id":"63B76600-E9CC-11E9-9B5F-82450873F7A1","full_name":"Stickler, Yvonne","last_name":"Stickler"},{"last_name":"Fröbe","full_name":"Fröbe, Ulrich","first_name":"Ulrich"},{"full_name":"Schlögl, Alois","last_name":"Schlögl","orcid":"0000-0002-5621-8100","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","first_name":"Alois"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","full_name":"Jonas, Peter M","last_name":"Jonas","orcid":"0000-0001-5001-4804"}],"department":[{"_id":"PeJo"},{"_id":"ScienComp"}],"volume":103,"month":"10","intvolume":"       103","scopus_import":"1","acknowledgement":"This work was supported by the Deutsche Forschungsgemeinschaft (TR3/B10) and a European Research Council Advanced grant to P.J.\r\nWe thank H. Hu, S. J. Guzman, and C. Schmidt-Hieber for critically reading the manuscript, I. Koeva and F. Marr for technical support, and E. Kramberger for editorial assistance.\r\n","language":[{"iso":"eng"}],"page":"1429 - 1439","oa_version":"Submitted Version","das_tickbox":"1","corr_author":"1","citation":{"short":"A. Pernia-Andrade, S. Goswami, Y. Stickler, U. Fröbe, A. Schlögl, P.M. Jonas, Biophysical Journal 103 (2012) 1429–1439.","ama":"Pernia-Andrade A, Goswami S, Stickler Y, Fröbe U, Schlögl A, Jonas PM. A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo. <i>Biophysical Journal</i>. 2012;103(7):1429-1439. doi:<a href=\"https://doi.org/10.1016/j.bpj.2012.08.039\">10.1016/j.bpj.2012.08.039</a>","apa":"Pernia-Andrade, A., Goswami, S., Stickler, Y., Fröbe, U., Schlögl, A., &#38; Jonas, P. M. (2012). A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo. <i>Biophysical Journal</i>. Biophysical Society. <a href=\"https://doi.org/10.1016/j.bpj.2012.08.039\">https://doi.org/10.1016/j.bpj.2012.08.039</a>","ista":"Pernia-Andrade A, Goswami S, Stickler Y, Fröbe U, Schlögl A, Jonas PM. 2012. A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo. Biophysical Journal. 103(7), 1429–1439.","chicago":"Pernia-Andrade, Alejandro, Sarit Goswami, Yvonne Stickler, Ulrich Fröbe, Alois Schlögl, and Peter M Jonas. “A Deconvolution Based Method with High Sensitivity and Temporal Resolution for Detection of Spontaneous Synaptic Currents in Vitro and in Vivo.” <i>Biophysical Journal</i>. Biophysical Society, 2012. <a href=\"https://doi.org/10.1016/j.bpj.2012.08.039\">https://doi.org/10.1016/j.bpj.2012.08.039</a>.","ieee":"A. Pernia-Andrade, S. Goswami, Y. Stickler, U. Fröbe, A. Schlögl, and P. M. Jonas, “A deconvolution based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo,” <i>Biophysical Journal</i>, vol. 103, no. 7. Biophysical Society, pp. 1429–1439, 2012.","mla":"Pernia-Andrade, Alejandro, et al. “A Deconvolution Based Method with High Sensitivity and Temporal Resolution for Detection of Spontaneous Synaptic Currents in Vitro and in Vivo.” <i>Biophysical Journal</i>, vol. 103, no. 7, Biophysical Society, 2012, pp. 1429–39, doi:<a href=\"https://doi.org/10.1016/j.bpj.2012.08.039\">10.1016/j.bpj.2012.08.039</a>."},"issue":"7"},{"status":"public","date_updated":"2025-09-30T09:25:10Z","doi":"10.1523/JNEUROSCI.6398-10.2011","oa":1,"publisher":"Wiley-Blackwell","title":"Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor","abstract":[{"text":"Spontaneous release of glutamate is important for maintaining synaptic strength and controlling spike timing in the brain. Mechanisms regulating spontaneous exocytosis remain poorly understood. Extracellular calcium concentration ([Ca2+]o) regulates Ca2+ entry through voltage-activated calcium channels (VACCs) and consequently is a pivotal determinant of action potential-evoked vesicle fusion. Extracellular Ca 2+ also enhances spontaneous release, but via unknown mechanisms. Here we report that external Ca2+ triggers spontaneous glutamate release more weakly than evoked release in mouse neocortical neurons. Blockade of VACCs has no effect on the spontaneous release rate or its dependence on [Ca2+]o. Intracellular [Ca2+] slowly increases in a minority of neurons following increases in [Ca2+]o. Furthermore, the enhancement of spontaneous release by extracellular calcium is insensitive to chelation of intracellular calcium by BAPTA. Activation of the calcium-sensing receptor (CaSR), a G-protein-coupled receptor present in nerve terminals, by several specific agonists increased spontaneous glutamate release. The frequency of spontaneous synaptic transmission was decreased in CaSR mutant neurons. The concentration-effect relationship for extracellular calcium regulation of spontaneous release was well described by a combination of CaSR-dependent and CaSR-independent mechanisms. Overall these results indicate that extracellular Ca2+ does not trigger spontaneous glutamate release by simply increasing calcium influx but stimulates CaSR and thereby promotes resting spontaneous glutamate release. ","lang":"eng"}],"quality_controlled":"1","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097128/","open_access":"1"}],"article_processing_charge":"No","day":"23","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"European Journal of Neuroscience","date_created":"2018-12-11T11:46:39Z","date_published":"2011-03-23T00:00:00Z","external_id":{"isi":["000288750700025"]},"_id":"469","year":"2011","publist_id":"7353","citation":{"ama":"Vyleta N, Smith S. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. 2011;31(12):4593-4606. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>","apa":"Vyleta, N., &#38; Smith, S. (2011). Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. <i>European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>","short":"N. Vyleta, S. Smith, European Journal of Neuroscience 31 (2011) 4593–4606.","ieee":"N. Vyleta and S. Smith, “Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor,” <i>European Journal of Neuroscience</i>, vol. 31, no. 12. Wiley-Blackwell, pp. 4593–4606, 2011.","chicago":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>. Wiley-Blackwell, 2011. <a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">https://doi.org/10.1523/JNEUROSCI.6398-10.2011</a>.","mla":"Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” <i>European Journal of Neuroscience</i>, vol. 31, no. 12, Wiley-Blackwell, 2011, pp. 4593–606, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.6398-10.2011\">10.1523/JNEUROSCI.6398-10.2011</a>.","ista":"Vyleta N, Smith S. 2011. Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor. European Journal of Neuroscience. 31(12), 4593–4606."},"issue":"12","intvolume":"        31","scopus_import":"1","publication_status":"published","isi":1,"author":[{"full_name":"Vyleta, Nicholas","last_name":"Vyleta","id":"36C4978E-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas"},{"first_name":"Stephen","full_name":"Smith, Stephen","last_name":"Smith"}],"department":[{"_id":"PeJo"}],"month":"03","volume":31,"language":[{"iso":"eng"}],"page":"4593 - 4606","oa_version":"Submitted Version"},{"article_number":"935364","corr_author":"1","citation":{"ama":"Schlögl A, Vidaurre C, Sander T. BioSig: The free and open source software library for biomedical signal processing. <i>Computational Intelligence and Neuroscience</i>. 2011;2011. doi:<a href=\"https://doi.org/10.1155/2011/935364\">10.1155/2011/935364</a>","apa":"Schlögl, A., Vidaurre, C., &#38; Sander, T. (2011). BioSig: The free and open source software library for biomedical signal processing. <i>Computational Intelligence and Neuroscience</i>. Hindawi Publishing Corporation. <a href=\"https://doi.org/10.1155/2011/935364\">https://doi.org/10.1155/2011/935364</a>","short":"A. Schlögl, C. Vidaurre, T. Sander, Computational Intelligence and Neuroscience 2011 (2011).","chicago":"Schlögl, Alois, Carmen Vidaurre, and Tilmann Sander. “BioSig: The Free and Open Source Software Library for Biomedical Signal Processing.” <i>Computational Intelligence and Neuroscience</i>. Hindawi Publishing Corporation, 2011. <a href=\"https://doi.org/10.1155/2011/935364\">https://doi.org/10.1155/2011/935364</a>.","ieee":"A. Schlögl, C. Vidaurre, and T. Sander, “BioSig: The free and open source software library for biomedical signal processing,” <i>Computational Intelligence and Neuroscience</i>, vol. 2011. Hindawi Publishing Corporation, 2011.","mla":"Schlögl, Alois, et al. “BioSig: The Free and Open Source Software Library for Biomedical Signal Processing.” <i>Computational Intelligence and Neuroscience</i>, vol. 2011, 935364, Hindawi Publishing Corporation, 2011, doi:<a href=\"https://doi.org/10.1155/2011/935364\">10.1155/2011/935364</a>.","ista":"Schlögl A, Vidaurre C, Sander T. 2011. BioSig: The free and open source software library for biomedical signal processing. Computational Intelligence and Neuroscience. 2011, 935364."},"has_accepted_license":"1","publication_status":"published","isi":1,"department":[{"_id":"ScienComp"},{"_id":"PeJo"}],"author":[{"first_name":"Alois","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5621-8100","full_name":"Schlögl, Alois","last_name":"Schlögl"},{"full_name":"Vidaurre, Carmen","last_name":"Vidaurre","first_name":"Carmen"},{"first_name":"Tilmann","full_name":"Sander, Tilmann","last_name":"Sander"}],"month":"01","volume":2011,"intvolume":"      2011","ddc":["005"],"scopus_import":"1","language":[{"iso":"eng"}],"oa_version":"Published Version","pubrep_id":"947","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"oa":1,"date_updated":"2025-09-30T09:24:43Z","doi":"10.1155/2011/935364","status":"public","publisher":"Hindawi Publishing Corporation","title":"BioSig: The free and open source software library for biomedical signal processing","abstract":[{"lang":"eng","text":"BioSig is an open source software library for biomedical signal processing. The aim of the BioSig project is to foster research in biomedical signal processing by providing free and open source software tools for many different application areas. Some of the areas where BioSig can be employed are neuroinformatics, brain-computer interfaces, neurophysiology, psychology, cardiovascular systems, and sleep research. Moreover, the analysis of biosignals such as the electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), or respiration signals is a very relevant element of the BioSig project. Specifically, BioSig provides solutions for data acquisition, artifact processing, quality control, feature extraction, classification, modeling, and data visualization, to name a few. In this paper, we highlight several methods to help students and researchers to work more efficiently with biomedical signals. "}],"quality_controlled":"1","file":[{"file_id":"4642","checksum":"8263bbf255171f2054f43f3db5f53b6e","content_type":"application/pdf","date_updated":"2020-07-14T12:46:35Z","file_name":"IST-2018-947-v1+1_2011_Schloegl_BioSig.pdf","relation":"main_file","date_created":"2018-12-12T10:07:44Z","access_level":"open_access","creator":"system","file_size":2863551}],"type":"journal_article","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication":"Computational Intelligence and Neuroscience","article_processing_charge":"No","day":"01","year":"2011","publist_id":"7330","file_date_updated":"2020-07-14T12:46:35Z","date_created":"2018-12-11T11:46:45Z","date_published":"2011-01-01T00:00:00Z","external_id":{"isi":["000208906100033"]},"_id":"490"},{"year":"2011","publist_id":"3321","date_created":"2018-12-11T12:02:38Z","date_published":"2011-12-04T00:00:00Z","_id":"3318","external_id":{"isi":["000298414400008"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"Nature Neuroscience","article_processing_charge":"No","day":"04","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631701/","open_access":"1"}],"publisher":"Nature Publishing Group","title":"How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses","quality_controlled":"1","abstract":[{"lang":"eng","text":"Parvalbumin is thought to act in a manner similar to EGTA, but how a slow Ca2+ buffer affects nanodomain-coupling regimes at GABAergic synapses is unclear. Direct measurements of parvalbumin concentration and paired recordings in rodent hippocampus and cerebellum revealed that parvalbumin affects synaptic dynamics only when expressed at high levels. Modeling suggests that, in high concentrations, parvalbumin may exert BAPTA-like effects, modulating nanodomain coupling via competition with local saturation of endogenous fixed buffers."}],"oa":1,"date_updated":"2025-09-30T09:20:05Z","status":"public","doi":"10.1038/nn.3002","language":[{"iso":"eng"}],"page":"20 - 22","oa_version":"Submitted Version","publication_status":"published","isi":1,"department":[{"_id":"PeJo"}],"author":[{"full_name":"Eggermann, Emmanuel","last_name":"Eggermann","first_name":"Emmanuel"},{"first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M"}],"month":"12","volume":15,"intvolume":"        15","scopus_import":"1","corr_author":"1","citation":{"mla":"Eggermann, Emmanuel, and Peter M. Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.” <i>Nature Neuroscience</i>, vol. 15, Nature Publishing Group, 2011, pp. 20–22, doi:<a href=\"https://doi.org/10.1038/nn.3002\">10.1038/nn.3002</a>.","ieee":"E. Eggermann and P. M. Jonas, “How the ‘slow’ Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses,” <i>Nature Neuroscience</i>, vol. 15. Nature Publishing Group, pp. 20–22, 2011.","chicago":"Eggermann, Emmanuel, and Peter M Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2011. <a href=\"https://doi.org/10.1038/nn.3002\">https://doi.org/10.1038/nn.3002</a>.","ista":"Eggermann E, Jonas PM. 2011. How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses. Nature Neuroscience. 15, 20–22.","apa":"Eggermann, E., &#38; Jonas, P. M. (2011). How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.3002\">https://doi.org/10.1038/nn.3002</a>","ama":"Eggermann E, Jonas PM. How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain coupling regimes at GABAergic synapses. <i>Nature Neuroscience</i>. 2011;15:20-22. doi:<a href=\"https://doi.org/10.1038/nn.3002\">10.1038/nn.3002</a>","short":"E. Eggermann, P.M. Jonas, Nature Neuroscience 15 (2011) 20–22."}},{"issue":"2","corr_author":"1","citation":{"chicago":"Pernia-Andrade, Alejandro, and Peter M Jonas. “The Multiple Faces of RIM.” <i>Neuron</i>. Elsevier, 2011. <a href=\"https://doi.org/10.1016/j.neuron.2011.01.010\">https://doi.org/10.1016/j.neuron.2011.01.010</a>.","ieee":"A. Pernia-Andrade and P. M. Jonas, “The multiple faces of RIM,” <i>Neuron</i>, vol. 69, no. 2. Elsevier, pp. 185–187, 2011.","mla":"Pernia-Andrade, Alejandro, and Peter M. Jonas. “The Multiple Faces of RIM.” <i>Neuron</i>, vol. 69, no. 2, Elsevier, 2011, pp. 185–87, doi:<a href=\"https://doi.org/10.1016/j.neuron.2011.01.010\">10.1016/j.neuron.2011.01.010</a>.","ista":"Pernia-Andrade A, Jonas PM. 2011. The multiple faces of RIM. Neuron. 69(2), 185–187.","ama":"Pernia-Andrade A, Jonas PM. The multiple faces of RIM. <i>Neuron</i>. 2011;69(2):185-187. doi:<a href=\"https://doi.org/10.1016/j.neuron.2011.01.010\">10.1016/j.neuron.2011.01.010</a>","apa":"Pernia-Andrade, A., &#38; Jonas, P. M. (2011). The multiple faces of RIM. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2011.01.010\">https://doi.org/10.1016/j.neuron.2011.01.010</a>","short":"A. Pernia-Andrade, P.M. Jonas, Neuron 69 (2011) 185–187."},"page":"185 - 187","oa_version":"None","language":[{"iso":"eng"}],"month":"01","volume":69,"publication_status":"published","isi":1,"author":[{"id":"36963E98-F248-11E8-B48F-1D18A9856A87","first_name":"Alejandro","last_name":"Pernia-Andrade","full_name":"Pernia-Andrade, Alejandro"},{"orcid":"0000-0001-5001-4804","last_name":"Jonas","full_name":"Jonas, Peter M","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"department":[{"_id":"PeJo"}],"intvolume":"        69","scopus_import":"1","publisher":"Elsevier","abstract":[{"text":"Rab3 interacting molecules (RIMs) are highly enriched in the active zones of presynaptic terminals. It is generally thought that they operate as effectors of the small G protein Rab3. Three recent papers, by Han et al. (this issue of Neuron), Deng et al. (this issue of Neuron), and Kaeser et al. (a recent issue of Cell), shed new light on the functional role of RIM in presynaptic terminals. First, RIM tethers Ca2+ channels to active zones. Second, RIM contributes to priming of synaptic vesicles by interacting with another presynaptic protein, Munc13.","lang":"eng"}],"quality_controlled":"1","title":"The multiple faces of RIM","date_updated":"2025-09-30T09:01:26Z","doi":"10.1016/j.neuron.2011.01.010","status":"public","year":"2011","publist_id":"3243","date_published":"2011-01-27T00:00:00Z","external_id":{"isi":["000286792900002"]},"_id":"3369","date_created":"2018-12-11T12:02:56Z","publication":"Neuron","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","article_processing_charge":"No","day":"27"},{"publication":"Neuropharmacology","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","article_processing_charge":"No","day":"01","year":"2010","publist_id":"2512","date_published":"2010-11-01T00:00:00Z","external_id":{"isi":["000283453300006"]},"_id":"3718","date_created":"2018-12-11T12:04:47Z","status":"public","date_updated":"2025-09-30T09:46:27Z","doi":"10.1016/j.neuropharm.2010.05.013","publisher":"Elsevier","abstract":[{"text":"Long-term depression (LTD) is a form of synaptic plasticity that may contribute to information storage in the central nervous system. Here we report that LTD can be elicited in layer 5 pyramidal neurons of the rat prefrontal cortex by pairing low frequency stimulation with a modest postsynaptic depolarization. The induction of LTD required the activation of both metabotropic glutamate receptors of the mGlu1 subtype and voltage-sensitive Ca(2+) channels (VSCCs) of the T/R, P/Q and N types, leading to the stimulation of intracellular inositol trisphosphate (IP3) receptors by IP3 and Ca(2+). The subsequent release of Ca(2+) from intracellular stores activated the protein phosphatase cascade involving calcineurin and protein phosphatase 1. The activation of purinergic P2Y(1) receptors blocked LTD. This effect was prevented by P2Y(1) receptor antagonists and was absent in mice lacking P2Y(1) but not P2Y(2) receptors. We also found that activation of P2Y(1) receptors inhibits Ca(2+) transients via VSCCs in the apical dendrites and spines of pyramidal neurons. In addition, we show that the release of ATP under hypoxia is able to inhibit LTD by acting on postsynaptic P2Y(1) receptors. In conclusion, these data suggest that the reduction of Ca(2+) influx via VSCCs caused by the activation of P2Y(1) receptors by ATP is the possible mechanism for the inhibition of LTD in prefrontal cortex.","lang":"eng"}],"title":"P2Y1 receptors inhibit long-term depression in the prefrontal cortex.","quality_controlled":"1","volume":59,"month":"11","isi":1,"publication_status":"published","author":[{"first_name":"José","id":"30CC5506-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2209-5242","full_name":"Guzmán, José","last_name":"Guzmán"},{"first_name":"Hartmut","last_name":"Schmidt","full_name":"Schmidt, Hartmut"},{"first_name":"Heike","full_name":"Franke, Heike","last_name":"Franke"},{"last_name":"Krügel","full_name":"Krügel, Ute","first_name":"Ute"},{"last_name":"Eilers","full_name":"Eilers, Jens","first_name":"Jens"},{"first_name":"Peter","last_name":"Illes","full_name":"Illes, Peter"},{"first_name":"Zoltan","last_name":"Gerevich","full_name":"Gerevich, Zoltan"}],"department":[{"_id":"PeJo"}],"acknowledgement":" The financial support of the Deutsche Forschungsgemeinschaft (IL 20/12-1, KI 677/2-4) is gratefully acknowledged.\r\nWe thank B. H. Koller (Department of Genetics and Molecular Biology, University of North Carolina at Chapel Hill, NC, USA) for the generous supply of P2Y1−/− and P2Y2−/− mice. We are grateful to Dr. A. Schulz for reanalysing the genotype of the P2Y1−/− mice. The authors thank P. Jonas and U. Heinemann for many helpful comments and A-K. Krause, L Feige and M. Eberts for their excellent technical support.","intvolume":"        59","scopus_import":"1","page":"406 - 415","oa_version":"None","language":[{"iso":"eng"}],"issue":"6","corr_author":"1","citation":{"ista":"Guzmán J, Schmidt H, Franke H, Krügel U, Eilers J, Illes P, Gerevich Z. 2010. P2Y1 receptors inhibit long-term depression in the prefrontal cortex. Neuropharmacology. 59(6), 406–415.","mla":"Guzmán, José, et al. “P2Y1 Receptors Inhibit Long-Term Depression in the Prefrontal Cortex.” <i>Neuropharmacology</i>, vol. 59, no. 6, Elsevier, 2010, pp. 406–15, doi:<a href=\"https://doi.org/10.1016/j.neuropharm.2010.05.013\">10.1016/j.neuropharm.2010.05.013</a>.","chicago":"Guzmán, José, Hartmut Schmidt, Heike Franke, Ute Krügel, Jens Eilers, Peter Illes, and Zoltan Gerevich. “P2Y1 Receptors Inhibit Long-Term Depression in the Prefrontal Cortex.” <i>Neuropharmacology</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.neuropharm.2010.05.013\">https://doi.org/10.1016/j.neuropharm.2010.05.013</a>.","ieee":"J. Guzmán <i>et al.</i>, “P2Y1 receptors inhibit long-term depression in the prefrontal cortex.,” <i>Neuropharmacology</i>, vol. 59, no. 6. Elsevier, pp. 406–415, 2010.","short":"J. Guzmán, H. Schmidt, H. Franke, U. Krügel, J. Eilers, P. Illes, Z. Gerevich, Neuropharmacology 59 (2010) 406–415.","apa":"Guzmán, J., Schmidt, H., Franke, H., Krügel, U., Eilers, J., Illes, P., &#38; Gerevich, Z. (2010). P2Y1 receptors inhibit long-term depression in the prefrontal cortex. <i>Neuropharmacology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuropharm.2010.05.013\">https://doi.org/10.1016/j.neuropharm.2010.05.013</a>","ama":"Guzmán J, Schmidt H, Franke H, et al. P2Y1 receptors inhibit long-term depression in the prefrontal cortex. <i>Neuropharmacology</i>. 2010;59(6):406-415. doi:<a href=\"https://doi.org/10.1016/j.neuropharm.2010.05.013\">10.1016/j.neuropharm.2010.05.013</a>"}},{"citation":{"ama":"Guzmán J, Jonas PM. Beyond TARPs: The growing list of auxiliary AMPAR subunits. <i>Neuron</i>. 2010;66(1):8-10. doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.04.003\">10.1016/j.neuron.2010.04.003</a>","apa":"Guzmán, J., &#38; Jonas, P. M. (2010). Beyond TARPs: The growing list of auxiliary AMPAR subunits. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2010.04.003\">https://doi.org/10.1016/j.neuron.2010.04.003</a>","short":"J. Guzmán, P.M. Jonas, Neuron 66 (2010) 8–10.","ieee":"J. Guzmán and P. M. Jonas, “Beyond TARPs: The growing list of auxiliary AMPAR subunits,” <i>Neuron</i>, vol. 66, no. 1. Elsevier, pp. 8–10, 2010.","chicago":"Guzmán, José, and Peter M Jonas. “Beyond TARPs: The Growing List of Auxiliary AMPAR Subunits.” <i>Neuron</i>. Elsevier, 2010. <a href=\"https://doi.org/10.1016/j.neuron.2010.04.003\">https://doi.org/10.1016/j.neuron.2010.04.003</a>.","mla":"Guzmán, José, and Peter M. Jonas. “Beyond TARPs: The Growing List of Auxiliary AMPAR Subunits.” <i>Neuron</i>, vol. 66, no. 1, Elsevier, 2010, pp. 8–10, doi:<a href=\"https://doi.org/10.1016/j.neuron.2010.04.003\">10.1016/j.neuron.2010.04.003</a>.","ista":"Guzmán J, Jonas PM. 2010. Beyond TARPs: The growing list of auxiliary AMPAR subunits. Neuron. 66(1), 8–10."},"corr_author":"1","issue":"1","scopus_import":"1","intvolume":"        66","ddc":["570"],"department":[{"_id":"PeJo"}],"author":[{"last_name":"Guzmán","full_name":"Guzmán, José","orcid":"0000-0003-2209-5242","id":"30CC5506-F248-11E8-B48F-1D18A9856A87","first_name":"José"},{"last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","first_name":"Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"}],"isi":1,"publication_status":"published","month":"04","volume":66,"language":[{"iso":"eng"}],"oa_version":"Published Version","page":"8 - 10","doi":"10.1016/j.neuron.2010.04.003","status":"public","date_updated":"2026-06-18T18:47:22Z","oa":1,"abstract":[{"text":"A recent paper by von Engelhardt et al. identifies a novel auxiliary subunit of native AMPARs, termedCKAMP44. Unlike other auxiliary subunits, CKAMP44 accelerates desensitization and prolongs recovery from desensitization. CKAMP44 is highly expressed in hippocampal dentate gyrus granule cells and decreases the paired-pulse ratio at perforant path input synapses. Thus, both principal and auxiliary AMPAR subunits control the time course of signaling at glutamatergic synapses.","lang":"eng"}],"quality_controlled":"1","title":"Beyond TARPs: The growing list of auxiliary AMPAR subunits","publisher":"Elsevier","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pubmed/20399724","open_access":"1"}],"day":"15","article_processing_charge":"No","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Neuron","pmid":1,"date_created":"2018-12-11T12:05:25Z","_id":"3832","external_id":{"isi":["000277016200004"],"pmid":["20399724"]},"date_published":"2010-04-15T00:00:00Z","publist_id":"2377","year":"2010"},{"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","type":"journal_article","publication":"The European Journal of Neuroscience","article_processing_charge":"No","day":"19","year":"2010","publist_id":"2378","date_created":"2018-12-11T12:05:25Z","date_published":"2010-03-19T00:00:00Z","_id":"3833","external_id":{"isi":["000276245400005"]},"doi":"10.1111/j.1460-9568.2010.07189.x","status":"public","date_updated":"2025-09-30T09:38:44Z","publisher":"Wiley-Blackwell","title":"GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &amp; Todorova)","quality_controlled":"1","publication_status":"published","isi":1,"author":[{"last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"},{"full_name":"Hefft, Stefan","last_name":"Hefft","first_name":"Stefan"}],"department":[{"_id":"PeJo"}],"volume":31,"month":"03","intvolume":"        31","scopus_import":"1","language":[{"iso":"eng"}],"page":"1194 - 1195","oa_version":"None","corr_author":"1","citation":{"ista":"Jonas PM, Hefft S. 2010. GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &#38;amp; Todorova). The European Journal of Neuroscience. 31(7), 1194–1195.","mla":"Jonas, Peter M., and Stefan Hefft. “GABA Release at Terminals of CCK-Interneurons: Synchrony, Asynchrony and Modulation by Cannabinoid Receptors (Commentary on Ali &#38;amp; Todorova).” <i>The European Journal of Neuroscience</i>, vol. 31, no. 7, Wiley-Blackwell, 2010, pp. 1194–95, doi:<a href=\"https://doi.org/10.1111/j.1460-9568.2010.07189.x\">10.1111/j.1460-9568.2010.07189.x</a>.","ieee":"P. M. Jonas and S. Hefft, “GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &#38;amp; Todorova),” <i>The European Journal of Neuroscience</i>, vol. 31, no. 7. Wiley-Blackwell, pp. 1194–1195, 2010.","chicago":"Jonas, Peter M, and Stefan Hefft. “GABA Release at Terminals of CCK-Interneurons: Synchrony, Asynchrony and Modulation by Cannabinoid Receptors (Commentary on Ali &#38;amp; Todorova).” <i>The European Journal of Neuroscience</i>. Wiley-Blackwell, 2010. <a href=\"https://doi.org/10.1111/j.1460-9568.2010.07189.x\">https://doi.org/10.1111/j.1460-9568.2010.07189.x</a>.","short":"P.M. Jonas, S. Hefft, The European Journal of Neuroscience 31 (2010) 1194–1195.","apa":"Jonas, P. M., &#38; Hefft, S. (2010). GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &#38;amp; Todorova). <i>The European Journal of Neuroscience</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/j.1460-9568.2010.07189.x\">https://doi.org/10.1111/j.1460-9568.2010.07189.x</a>","ama":"Jonas PM, Hefft S. GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali &#38;amp; Todorova). <i>The European Journal of Neuroscience</i>. 2010;31(7):1194-1195. doi:<a href=\"https://doi.org/10.1111/j.1460-9568.2010.07189.x\">10.1111/j.1460-9568.2010.07189.x</a>"},"issue":"7"}]