---
_id: '2062'
abstract:
- lang: eng
text: The success story of fast-spiking, parvalbumin-positive (PV+) GABAergic interneurons
(GABA, γ-aminobutyric acid) in the mammalian central nervous system is noteworthy.
In 1995, the properties of these interneurons were completely unknown. Twenty
years later, thanks to the massive use of subcellular patch-clamp techniques,
simultaneous multiple-cell recording, optogenetics, in vivo measurements, and
computational approaches, our knowledge about PV+ interneurons became more extensive
than for several types of pyramidal neurons. These findings have implications
beyond the “small world” of basic research on GABAergic cells. For example, the
results provide a first proof of principle that neuroscientists might be able
to close the gaps between the molecular, cellular, network, and behavioral levels,
representing one of the main challenges at the present time. Furthermore, the
results may form the basis for PV+ interneurons as therapeutic targets for brain
disease in the future. However, much needs to be learned about the basic function
of these interneurons before clinical neuroscientists will be able to use PV+
interneurons for therapeutic purposes.
article_number: '1255263'
article_processing_charge: No
author:
- first_name: Hua
full_name: Hu, Hua
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Jian
full_name: Gan, Jian
id: 3614E438-F248-11E8-B48F-1D18A9856A87
last_name: Gan
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Hu H, Gan J, Jonas PM. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 2014;345(6196).
doi:10.1126/science.1255263'
apa: 'Hu, H., Gan, J., & Jonas, P. M. (2014). Fast-spiking parvalbumin^+ GABAergic
interneurons: From cellular design to microcircuit function. Science. American
Association for the Advancement of Science. https://doi.org/10.1126/science.1255263'
chicago: 'Hu, Hua, Jian Gan, and Peter M Jonas. “Fast-Spiking Parvalbumin^+ GABAergic
Interneurons: From Cellular Design to Microcircuit Function.” Science.
American Association for the Advancement of Science, 2014. https://doi.org/10.1126/science.1255263.'
ieee: 'H. Hu, J. Gan, and P. M. Jonas, “Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function,” Science, vol. 345, no.
6196. American Association for the Advancement of Science, 2014.'
ista: 'Hu H, Gan J, Jonas PM. 2014. Fast-spiking parvalbumin^+ GABAergic interneurons:
From cellular design to microcircuit function. Science. 345(6196), 1255263.'
mla: 'Hu, Hua, et al. “Fast-Spiking Parvalbumin^+ GABAergic Interneurons: From Cellular
Design to Microcircuit Function.” Science, vol. 345, no. 6196, 1255263,
American Association for the Advancement of Science, 2014, doi:10.1126/science.1255263.'
short: H. Hu, J. Gan, P.M. Jonas, Science 345 (2014).
corr_author: '1'
date_created: 2018-12-11T11:55:29Z
date_published: 2014-08-01T00:00:00Z
date_updated: 2025-09-29T11:48:03Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1126/science.1255263
ec_funded: 1
external_id:
isi:
- '000339651300036'
file:
- access_level: open_access
checksum: a0036a589037d37e86364fa25cc0a82f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:00Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5185'
file_name: IST-2017-821-v1+1_1255263JonasPVReviewTextR_Final.pdf
file_size: 215514
relation: main_file
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checksum: e1f57d2713725449cb898fdcb8ef47b8
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:16:01Z
date_updated: 2020-07-14T12:45:27Z
file_id: '5186'
file_name: IST-2017-821-v1+2_1255263JonasPVReviewFigures_Final.pdf
file_size: 1732723
relation: main_file
file_date_updated: 2020-07-14T12:45:27Z
has_accepted_license: '1'
intvolume: ' 345'
isi: 1
issue: '6196'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P24909-B24
name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '268548'
name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4984'
pubrep_id: '821'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Fast-spiking parvalbumin^+ GABAergic interneurons: From cellular design to
microcircuit function'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 345
year: '2014'
...
---
_id: '10396'
abstract:
- lang: eng
text: Stimfit is a free cross-platform software package for viewing and analyzing
electrophysiological data. It supports most standard file types for cellular neurophysiology
and other biomedical formats. Its analysis algorithms have been used and validated
in several experimental laboratories. Its embedded Python scripting interface
makes Stimfit highly extensible and customizable.
article_number: '000010151520134181'
article_processing_charge: No
article_type: original
author:
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: C.
full_name: Schmidt-Hieber, C.
last_name: Schmidt-Hieber
- first_name: S. J.
full_name: Guzman, S. J.
last_name: Guzman
citation:
ama: 'Schlögl A, Jonas PM, Schmidt-Hieber C, Guzman SJ. Stimfit: A fast visualization
and analysis environment for cellular neurophysiology. Biomedical Engineering
/ Biomedizinische Technik. 2013;58(SI-1-Track-G). doi:10.1515/bmt-2013-4181'
apa: 'Schlögl, A., Jonas, P. M., Schmidt-Hieber, C., & Guzman, S. J. (2013).
Stimfit: A fast visualization and analysis environment for cellular neurophysiology.
Biomedical Engineering / Biomedizinische Technik. Graz, Austria: De Gruyter.
https://doi.org/10.1515/bmt-2013-4181'
chicago: 'Schlögl, Alois, Peter M Jonas, C. Schmidt-Hieber, and S. J. Guzman. “Stimfit:
A Fast Visualization and Analysis Environment for Cellular Neurophysiology.” Biomedical
Engineering / Biomedizinische Technik. De Gruyter, 2013. https://doi.org/10.1515/bmt-2013-4181.'
ieee: 'A. Schlögl, P. M. Jonas, C. Schmidt-Hieber, and S. J. Guzman, “Stimfit: A
fast visualization and analysis environment for cellular neurophysiology,” Biomedical
Engineering / Biomedizinische Technik, vol. 58, no. SI-1-Track-G. De Gruyter,
2013.'
ista: 'Schlögl A, Jonas PM, Schmidt-Hieber C, Guzman SJ. 2013. Stimfit: A fast visualization
and analysis environment for cellular neurophysiology. Biomedical Engineering
/ Biomedizinische Technik. 58(SI-1-Track-G), 000010151520134181.'
mla: 'Schlögl, Alois, et al. “Stimfit: A Fast Visualization and Analysis Environment
for Cellular Neurophysiology.” Biomedical Engineering / Biomedizinische Technik,
vol. 58, no. SI-1-Track-G, 000010151520134181, De Gruyter, 2013, doi:10.1515/bmt-2013-4181.'
short: A. Schlögl, P.M. Jonas, C. Schmidt-Hieber, S.J. Guzman, Biomedical Engineering
/ Biomedizinische Technik 58 (2013).
conference:
end_date: 2013-09-21
location: Graz, Austria
name: 'BMT: Biomedizinische Technik '
start_date: 2013-09-19
corr_author: '1'
date_created: 2021-12-01T14:35:35Z
date_published: 2013-08-01T00:00:00Z
date_updated: 2025-09-30T07:31:23Z
day: '01'
ddc:
- '005'
- '610'
department:
- _id: PeJo
doi: 10.1515/bmt-2013-4181
external_id:
isi:
- '000497714000034'
pmid:
- '24042795'
file:
- access_level: open_access
checksum: cdfc5339b530a25d6079f7223f0b1f16
content_type: application/pdf
creator: schloegl
date_created: 2021-12-01T14:38:08Z
date_updated: 2021-12-01T14:38:08Z
file_id: '10397'
file_name: Schloegl_Abstract-BMT2013.pdf
file_size: 149825
relation: main_file
success: 1
file_date_updated: 2021-12-01T14:38:08Z
has_accepted_license: '1'
intvolume: ' 58'
isi: 1
issue: SI-1-Track-G
keyword:
- biomedical engineering
- data analysis
- free software
language:
- iso: eng
month: '08'
oa: 1
oa_version: Submitted Version
pmid: 1
publication: Biomedical Engineering / Biomedizinische Technik
publication_identifier:
eissn:
- 1862-278X
issn:
- 0013-5585
publication_status: published
publisher: De Gruyter
quality_controlled: '1'
status: public
title: 'Stimfit: A fast visualization and analysis environment for cellular neurophysiology'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 58
year: '2013'
...
---
OA_place: publisher
_id: '2964'
abstract:
- lang: eng
text: 'CA3 pyramidal neurons are important for memory formation and pattern completion
in the hippocampal network. These neurons receive multiple excitatory inputs from
numerous sources. Therefore, the rules of spatiotemporal integration of multiple
synaptic inputs and propagation of action potentials are important to understand
how CA3 neurons contribute to higher brain functions at cellular level. By using
confocally targeted patch-clamp recording techniques, we investigated the biophysical
properties of rat CA3 pyramidal neuron dendrites. We found two distinct dendritic
domains critical for action potential initiation and propagation: In the proximal
domain, action potentials initiated in the axon backpropagate actively with large
amplitude and fast time course. In the distal domain, Na+-channel mediated dendritic
spikes are efficiently evoked by local dendritic depolarization or waveforms mimicking
synaptic events. These findings can be explained by a high Na+-to-K+ conductance
density ratio of CA3 pyramidal neuron dendrites. The results challenge the prevailing
view that proximal mossy fiber inputs activate CA3 pyramidal neurons more efficiently
than distal perforant inputs by showing that the distal synapses trigger a different
form of activity represented by dendritic spikes. The high probability of dendritic
spike initiation in the distal area may enhance the computational power of CA3
pyramidal neurons in the hippocampal network. '
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Sooyun
full_name: Kim, Sooyun
id: 394AB1C8-F248-11E8-B48F-1D18A9856A87
last_name: Kim
citation:
ama: Kim S. Active properties of hippocampal CA3 pyramidal neuron dendrites. 2012.
apa: Kim, S. (2012). Active properties of hippocampal CA3 pyramidal neuron dendrites.
Institute of Science and Technology Austria.
chicago: Kim, Sooyun. “Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites.”
Institute of Science and Technology Austria, 2012.
ieee: S. Kim, “Active properties of hippocampal CA3 pyramidal neuron dendrites,”
Institute of Science and Technology Austria, 2012.
ista: Kim S. 2012. Active properties of hippocampal CA3 pyramidal neuron dendrites.
Institute of Science and Technology Austria.
mla: Kim, Sooyun. Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites.
Institute of Science and Technology Austria, 2012.
short: S. Kim, Active Properties of Hippocampal CA3 Pyramidal Neuron Dendrites,
Institute of Science and Technology Austria, 2012.
corr_author: '1'
date_created: 2018-12-11T12:00:35Z
date_published: 2012-06-01T00:00:00Z
date_updated: 2026-06-18T18:41:53Z
day: '01'
degree_awarded: PhD
department:
- _id: PeJo
- _id: GradSch
language:
- iso: eng
month: '06'
oa_version: None
page: '65'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
publist_id: '3755'
related_material:
record:
- id: '3258'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
title: Active properties of hippocampal CA3 pyramidal neuron dendrites
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2012'
...
---
_id: '2969'
abstract:
- lang: eng
text: "The coupling between presynaptic Ca^(2+) channels and Ca^(2+) sensors of
exocytosis is a key determinant of synaptic transmission. Evoked release from
parvalbumin (PV)-expressing interneurons is triggered by nanodomain coupling of
P/Q-type Ca^(2+) channels, whereas release from cholecystokinin (CCK)-containing
interneurons is generated by microdomain coupling of N-type channels. Nanodomain
coupling has several functional advantages, including speed and efficacy of transmission.
One potential disadvantage is that stochastic\r\nopening of presynaptic Ca^(2+)
channels may trigger spontaneous transmitter release. We addressed this possibility
in rat hippocampal\r\ngranule cells, which receive converging inputs from different
inhibitory sources. Both reduction of extracellular Ca^(2+) concentration and
the unselective Ca^(2+) channel blocker Cd^(2+) reduced the frequency of miniature
IPSCs (mIPSCs) in granule cells by ~50%, suggesting that the opening of presynaptic
Ca^(2+) channels contributes to spontaneous release. Application of the selective
P/Q-type Ca^(2+) channel blocker\r\nω-agatoxin IVa had no detectable effects,
whereas both the N-type blocker ω-conotoxin GVIa and the L-type blocker nimodipine
reduced\r\nmIPSC frequency. Furthermore, both the fast Ca^(2+) chelator BAPTA-AM
and the slow chelator EGTA-AM reduced the mIPSC frequency,\r\nsuggesting that
Ca^(2+)-dependent spontaneous release is triggered by microdomain rather than
nanodomain coupling. The CB_(1) receptor\r\nagonist WIN 55212-2 also decreased
spontaneous release; this effect was occluded by prior application of ω-conotoxin
GVIa, suggesting that a major fraction of Ca^(2+)-dependent spontaneous release
was generated at the terminals of CCK-expressing interneurons. Tonic inhibition
generated by spontaneous opening of presynaptic N- and L-type Ca^(2+) channels
may be important for hippocampal information processing.\r\n"
acknowledgement: This work was supported by grants from the Deutsche Forschungsgemeinschaft
(TR 3/B10, Leibniz program, GSC-4 Spemann Graduate School) and the European Union
(European Research Council Advanced Grant).
article_processing_charge: No
author:
- first_name: Sarit
full_name: Goswami, Sarit
id: 3A578F32-F248-11E8-B48F-1D18A9856A87
last_name: Goswami
- first_name: Iancu
full_name: Bucurenciu, Iancu
last_name: Bucurenciu
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Goswami S, Bucurenciu I, Jonas PM. Miniature IPSCs in hippocampal granule cells
are triggered by voltage-gated Ca^(2+) channels via microdomain coupling. Journal
of Neuroscience. 2012;32(41):14294-14304. doi:10.1523/JNEUROSCI.6104-11.2012
apa: Goswami, S., Bucurenciu, I., & Jonas, P. M. (2012). Miniature IPSCs in
hippocampal granule cells are triggered by voltage-gated Ca^(2+) channels via
microdomain coupling. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.6104-11.2012
chicago: Goswami, Sarit, Iancu Bucurenciu, and Peter M Jonas. “Miniature IPSCs in
Hippocampal Granule Cells Are Triggered by Voltage-Gated Ca^(2+) Channels via
Microdomain Coupling.” Journal of Neuroscience. Society for Neuroscience,
2012. https://doi.org/10.1523/JNEUROSCI.6104-11.2012.
ieee: S. Goswami, I. Bucurenciu, and P. M. Jonas, “Miniature IPSCs in hippocampal
granule cells are triggered by voltage-gated Ca^(2+) channels via microdomain
coupling,” Journal of Neuroscience, vol. 32, no. 41. Society for Neuroscience,
pp. 14294–14304, 2012.
ista: Goswami S, Bucurenciu I, Jonas PM. 2012. Miniature IPSCs in hippocampal granule
cells are triggered by voltage-gated Ca^(2+) channels via microdomain coupling.
Journal of Neuroscience. 32(41), 14294–14304.
mla: Goswami, Sarit, et al. “Miniature IPSCs in Hippocampal Granule Cells Are Triggered
by Voltage-Gated Ca^(2+) Channels via Microdomain Coupling.” Journal of Neuroscience,
vol. 32, no. 41, Society for Neuroscience, 2012, pp. 14294–304, doi:10.1523/JNEUROSCI.6104-11.2012.
short: S. Goswami, I. Bucurenciu, P.M. Jonas, Journal of Neuroscience 32 (2012)
14294–14304.
corr_author: '1'
date_created: 2018-12-11T12:00:36Z
date_published: 2012-10-10T00:00:00Z
date_updated: 2025-09-30T08:03:27Z
day: '10'
department:
- _id: PeJo
doi: 10.1523/JNEUROSCI.6104-11.2012
external_id:
isi:
- '000309963700030'
pmid:
- '23055500'
intvolume: ' 32'
isi: 1
issue: '41'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632771/
month: '10'
oa: 1
oa_version: Submitted Version
page: 14294 - 14304
pmid: 1
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '3744'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Miniature IPSCs in hippocampal granule cells are triggered by voltage-gated
Ca^(2+) channels via microdomain coupling
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 32
year: '2012'
...
---
_id: '493'
abstract:
- lang: eng
text: 'The BCI competition IV stands in the tradition of prior BCI competitions
that aim to provide high quality neuroscientific data for open access to the scientific
community. As experienced already in prior competitions not only scientists from
the narrow field of BCI compete, but scholars with a broad variety of backgrounds
and nationalities. They include high specialists as well as students.The goals
of all BCI competitions have always been to challenge with respect to novel paradigms
and complex data. We report on the following challenges: (1) asynchronous data,
(2) synthetic, (3) multi-class continuous data, (4) sessionto-session transfer,
(5) directionally modulated MEG, (6) finger movements recorded by ECoG. As after
past competitions, our hope is that winning entries may enhance the analysis methods
of future BCIs.'
acknowledgement: "The studies were in part or completely supported by the Bundesministerium
für Bildung und Forschung (BMBF), Fkz 01IB001A, 01GQ0850, by the German Science
Foundation (DFG, contract MU 987/3-2), by the European ICT Programme Projects FP7-224631
and 216886, the World Class University Program through the National Research Foundation
of Korea funded by the Ministry of Education, Science, and Technology (Grant R31-10008),
the US Army Research Office [W911NF-08-1-0216 (Gerwin Schalk) and W911NF-07-1-0415
(Gerwin Schalk)] and the NIH [EB006356 (Gerwin Schalk) and EB000856 (Gerwin Schalk),
the WIN-Kolleg of the Heidelberg Academy of Sciences and Humanities, German Federal
Ministry of Education and Research grants 01GQ0420, 01GQ0761, 01GQ0762, and 01GQ0830,
German Research Foundation grants 550/B5 and C6, and by a scholarship from the German
National Academic Foundation. This paper only reflects the authors’ views and funding
agencies are not liable for any use that may be made of the information contained
herein.\r\n"
article_number: '55'
article_processing_charge: No
author:
- first_name: Michael
full_name: Tangermann, Michael
last_name: Tangermann
- first_name: Klaus
full_name: Müller, Klaus
last_name: Müller
- first_name: Ad
full_name: Aertsen, Ad
last_name: Aertsen
- first_name: Niels
full_name: Birbaumer, Niels
last_name: Birbaumer
- first_name: Christoph
full_name: Braun, Christoph
last_name: Braun
- first_name: Clemens
full_name: Brunner, Clemens
last_name: Brunner
- first_name: Robert
full_name: Leeb, Robert
last_name: Leeb
- first_name: Carsten
full_name: Mehring, Carsten
last_name: Mehring
- first_name: Kai
full_name: Miller, Kai
last_name: Miller
- first_name: Gernot
full_name: Müller Putz, Gernot
last_name: Müller Putz
- first_name: Guido
full_name: Nolte, Guido
last_name: Nolte
- first_name: Gert
full_name: Pfurtscheller, Gert
last_name: Pfurtscheller
- first_name: Hubert
full_name: Preissl, Hubert
last_name: Preissl
- first_name: Gerwin
full_name: Schalk, Gerwin
last_name: Schalk
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Carmen
full_name: Vidaurre, Carmen
last_name: Vidaurre
- first_name: Stephan
full_name: Waldert, Stephan
last_name: Waldert
- first_name: Benjamin
full_name: Blankertz, Benjamin
last_name: Blankertz
citation:
ama: Tangermann M, Müller K, Aertsen A, et al. Review of the BCI competition IV.
Frontiers in Neuroscience. 2012;6. doi:10.3389/fnins.2012.00055
apa: Tangermann, M., Müller, K., Aertsen, A., Birbaumer, N., Braun, C., Brunner,
C., … Blankertz, B. (2012). Review of the BCI competition IV. Frontiers in
Neuroscience. Frontiers Research Foundation. https://doi.org/10.3389/fnins.2012.00055
chicago: Tangermann, Michael, Klaus Müller, Ad Aertsen, Niels Birbaumer, Christoph
Braun, Clemens Brunner, Robert Leeb, et al. “Review of the BCI Competition IV.”
Frontiers in Neuroscience. Frontiers Research Foundation, 2012. https://doi.org/10.3389/fnins.2012.00055.
ieee: M. Tangermann et al., “Review of the BCI competition IV,” Frontiers
in Neuroscience, vol. 6. Frontiers Research Foundation, 2012.
ista: Tangermann M, Müller K, Aertsen A, Birbaumer N, Braun C, Brunner C, Leeb R,
Mehring C, Miller K, Müller Putz G, Nolte G, Pfurtscheller G, Preissl H, Schalk
G, Schlögl A, Vidaurre C, Waldert S, Blankertz B. 2012. Review of the BCI competition
IV. Frontiers in Neuroscience. 6, 55.
mla: Tangermann, Michael, et al. “Review of the BCI Competition IV.” Frontiers
in Neuroscience, vol. 6, 55, Frontiers Research Foundation, 2012, doi:10.3389/fnins.2012.00055.
short: M. Tangermann, K. Müller, A. Aertsen, N. Birbaumer, C. Braun, C. Brunner,
R. Leeb, C. Mehring, K. Miller, G. Müller Putz, G. Nolte, G. Pfurtscheller, H.
Preissl, G. Schalk, A. Schlögl, C. Vidaurre, S. Waldert, B. Blankertz, Frontiers
in Neuroscience 6 (2012).
date_created: 2018-12-11T11:46:46Z
date_published: 2012-07-13T00:00:00Z
date_updated: 2025-09-30T08:35:59Z
day: '13'
ddc:
- '004'
department:
- _id: ScienComp
- _id: PeJo
doi: 10.3389/fnins.2012.00055
external_id:
isi:
- '000209165300066'
file:
- access_level: open_access
checksum: 195238221c4b0b0f4035f6f6c16ea17c
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:18:34Z
date_updated: 2020-07-14T12:46:35Z
file_id: '5356'
file_name: IST-2018-945-v1+1_2012_Schloegl_Review_of.pdf
file_size: 2693701
relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
has_accepted_license: '1'
intvolume: ' 6'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Frontiers in Neuroscience
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '7327'
pubrep_id: '945'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Review of the BCI competition IV
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2012'
...
---
_id: '3121'
abstract:
- lang: eng
text: Voltage-activated Ca(2+) channels (VACCs) mediate Ca(2+) influx to trigger
action potential-evoked neurotransmitter release, but the mechanism by which Ca(2+)
regulates spontaneous transmission is unclear. We found that VACCs are the major
physiological triggers for spontaneous release at mouse neocortical inhibitory
synapses. Moreover, despite the absence of a synchronizing action potential, we
found that spontaneous fusion of a GABA-containing vesicle required the activation
of multiple tightly coupled VACCs of variable type.
acknowledgement: "The work was supported by the US National Institutes of Health (DA027110
and GM097433) and OCTRI. C.W. and N.P.V. were supported by a grant from the National
Heart, Lung, and Blood Institute (T32HL033808).\r\nWe thank M. Andresen and K. Khodakhah
for helpful comments. "
article_processing_charge: No
author:
- first_name: Courtney
full_name: Williams, Courtney
last_name: Williams
- first_name: Wenyan
full_name: Chen, Wenyan
last_name: Chen
- first_name: Chia
full_name: Lee, Chia
last_name: Lee
- first_name: Daniel
full_name: Yaeger, Daniel
last_name: Yaeger
- first_name: Nicholas
full_name: Vyleta, Nicholas
id: 36C4978E-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Stephen
full_name: Smith, Stephen
last_name: Smith
citation:
ama: Williams C, Chen W, Lee C, Yaeger D, Vyleta N, Smith S. Coactivation of multiple
tightly coupled calcium channels triggers spontaneous release of GABA. Nature
Neuroscience. 2012;15(9):1195-1197. doi:10.1038/nn.3162
apa: Williams, C., Chen, W., Lee, C., Yaeger, D., Vyleta, N., & Smith, S. (2012).
Coactivation of multiple tightly coupled calcium channels triggers spontaneous
release of GABA. Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3162
chicago: Williams, Courtney, Wenyan Chen, Chia Lee, Daniel Yaeger, Nicholas Vyleta,
and Stephen Smith. “Coactivation of Multiple Tightly Coupled Calcium Channels
Triggers Spontaneous Release of GABA.” Nature Neuroscience. Nature Publishing
Group, 2012. https://doi.org/10.1038/nn.3162.
ieee: C. Williams, W. Chen, C. Lee, D. Yaeger, N. Vyleta, and S. Smith, “Coactivation
of multiple tightly coupled calcium channels triggers spontaneous release of GABA,”
Nature Neuroscience, vol. 15, no. 9. Nature Publishing Group, pp. 1195–1197,
2012.
ista: Williams C, Chen W, Lee C, Yaeger D, Vyleta N, Smith S. 2012. Coactivation
of multiple tightly coupled calcium channels triggers spontaneous release of GABA.
Nature Neuroscience. 15(9), 1195–1197.
mla: Williams, Courtney, et al. “Coactivation of Multiple Tightly Coupled Calcium
Channels Triggers Spontaneous Release of GABA.” Nature Neuroscience, vol.
15, no. 9, Nature Publishing Group, 2012, pp. 1195–97, doi:10.1038/nn.3162.
short: C. Williams, W. Chen, C. Lee, D. Yaeger, N. Vyleta, S. Smith, Nature Neuroscience
15 (2012) 1195–1197.
date_created: 2018-12-11T12:01:30Z
date_published: 2012-09-01T00:00:00Z
date_updated: 2025-09-30T07:59:27Z
day: '01'
department:
- _id: PeJo
doi: 10.1038/nn.3162
external_id:
isi:
- '000308072600008'
pmid:
- '22842148'
intvolume: ' 15'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431448/
month: '09'
oa: 1
oa_version: Submitted Version
page: 1195 - 1197
pmid: 1
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '3578'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Coactivation of multiple tightly coupled calcium channels triggers spontaneous
release of GABA
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2012'
...
---
_id: '3258'
abstract:
- lang: eng
text: CA3 pyramidal neurons are important for memory formation and pattern completion
in the hippocampal network. It is generally thought that proximal synapses from
the mossy fibers activate these neurons most efficiently, whereas distal inputs
from the perforant path have a weaker modulatory influence. We used confocally
targeted patch-clamp recording from dendrites and axons to map the activation
of rat CA3 pyramidal neurons at the subcellular level. Our results reveal two
distinct dendritic domains. In the proximal domain, action potentials initiated
in the axon backpropagate actively with large amplitude and fast time course.
In the distal domain, Na+ channel–mediated dendritic spikes are efficiently initiated
by waveforms mimicking synaptic events. CA3 pyramidal neuron dendrites showed
a high Na+-to-K+ conductance density ratio, providing ideal conditions for active
backpropagation and dendritic spike initiation. Dendritic spikes may enhance the
computational power of CA3 pyramidal neurons in the hippocampal network.
acknowledgement: This work was supported by the Deutsche Forschungsgemeinschaft (TR
3/B10) and the European Union (European Research Council Advanced grant to P.J.).
article_processing_charge: No
article_type: original
author:
- first_name: Sooyun
full_name: Kim, Sooyun
id: 394AB1C8-F248-11E8-B48F-1D18A9856A87
last_name: Kim
- first_name: José
full_name: Guzmán, José
id: 30CC5506-F248-11E8-B48F-1D18A9856A87
last_name: Guzmán
orcid: 0000-0003-2209-5242
- first_name: Hua
full_name: Hu, Hua
id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
last_name: Hu
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Kim S, Guzmán J, Hu H, Jonas PM. Active dendrites support efficient initiation
of dendritic spikes in hippocampal CA3 pyramidal neurons. Nature Neuroscience.
2012;15(4):600-606. doi:10.1038/nn.3060
apa: Kim, S., Guzmán, J., Hu, H., & Jonas, P. M. (2012). Active dendrites support
efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3060
chicago: Kim, Sooyun, José Guzmán, Hua Hu, and Peter M Jonas. “Active Dendrites
Support Efficient Initiation of Dendritic Spikes in Hippocampal CA3 Pyramidal
Neurons.” Nature Neuroscience. Nature Publishing Group, 2012. https://doi.org/10.1038/nn.3060.
ieee: S. Kim, J. Guzmán, H. Hu, and P. M. Jonas, “Active dendrites support efficient
initiation of dendritic spikes in hippocampal CA3 pyramidal neurons,” Nature
Neuroscience, vol. 15, no. 4. Nature Publishing Group, pp. 600–606, 2012.
ista: Kim S, Guzmán J, Hu H, Jonas PM. 2012. Active dendrites support efficient
initiation of dendritic spikes in hippocampal CA3 pyramidal neurons. Nature Neuroscience.
15(4), 600–606.
mla: Kim, Sooyun, et al. “Active Dendrites Support Efficient Initiation of Dendritic
Spikes in Hippocampal CA3 Pyramidal Neurons.” Nature Neuroscience, vol.
15, no. 4, Nature Publishing Group, 2012, pp. 600–06, doi:10.1038/nn.3060.
short: S. Kim, J. Guzmán, H. Hu, P.M. Jonas, Nature Neuroscience 15 (2012) 600–606.
corr_author: '1'
date_created: 2018-12-11T12:02:18Z
date_published: 2012-04-01T00:00:00Z
date_updated: 2026-06-18T18:41:54Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1038/nn.3060
external_id:
isi:
- '000302114500020'
pmid:
- '22388958'
intvolume: ' 15'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617474/
month: '04'
oa: 1
oa_version: Published Version
page: 600 - 606
pmid: 1
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Nature Neuroscience
publication_identifier:
issn:
- 1546-1726
publication_status: published
publisher: Nature Publishing Group
publist_id: '3390'
quality_controlled: '1'
related_material:
record:
- id: '2964'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Active dendrites support efficient initiation of dendritic spikes in hippocampal
CA3 pyramidal neurons
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2012'
...
---
_id: '3317'
abstract:
- lang: eng
text: The physical distance between presynaptic Ca2+ channels and the Ca2+ sensors
that trigger exocytosis of neurotransmitter-containing vesicles is a key determinant
of the signalling properties of synapses in the nervous system. Recent functional
analysis indicates that in some fast central synapses, transmitter release is
triggered by a small number of Ca2+ channels that are coupled to Ca2+ sensors
at the nanometre scale. Molecular analysis suggests that this tight coupling is
generated by protein–protein interactions involving Ca2+ channels, Ca2+ sensors
and various other synaptic proteins. Nanodomain coupling has several functional
advantages, as it increases the efficacy, speed and energy efficiency of synaptic
transmission.
acknowledgement: "Work of the authors was funded by grants of the Deutsche Forschungsgemeinschaft
to P.J. (grants SFB 780/A5, TR 3/B10 and the Leibniz programme), a European Research
Council Advanced grant to P.J. and a Swiss National Foundation fellowship to E.E.\r\nWe
thank D. Tsien and E. Neher for their comments on this Review, J. Guzmán and A.
Pernía-Andrade for reading earlier versions and E. Kramberger for perfect editorial
support. We apologize that owing to space constraints, not all relevant papers could
be cited.\r\n"
article_processing_charge: No
author:
- first_name: Emmanuel
full_name: Eggermann, Emmanuel
id: 34DACA34-E9AE-11E9-849C-D35BD8ADC20C
last_name: Eggermann
- first_name: Iancu
full_name: Bucurenciu, Iancu
id: 4BD1D872-E9AE-11E9-9EE9-8BF4597A9E2A
last_name: Bucurenciu
- first_name: Sarit
full_name: Goswami, Sarit
id: 3A578F32-F248-11E8-B48F-1D18A9856A87
last_name: Goswami
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Eggermann E, Bucurenciu I, Goswami S, Jonas PM. Nanodomain coupling between
Ca(2+) channels and sensors of exocytosis at fast mammalian synapses. Nature
Reviews Neuroscience. 2012;13(1):7-21. doi:10.1038/nrn3125
apa: Eggermann, E., Bucurenciu, I., Goswami, S., & Jonas, P. M. (2012). Nanodomain
coupling between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses.
Nature Reviews Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nrn3125
chicago: Eggermann, Emmanuel, Iancu Bucurenciu, Sarit Goswami, and Peter M Jonas.
“Nanodomain Coupling between Ca(2+) Channels and Sensors of Exocytosis at Fast
Mammalian Synapses.” Nature Reviews Neuroscience. Nature Publishing Group,
2012. https://doi.org/10.1038/nrn3125.
ieee: E. Eggermann, I. Bucurenciu, S. Goswami, and P. M. Jonas, “Nanodomain coupling
between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses,”
Nature Reviews Neuroscience, vol. 13, no. 1. Nature Publishing Group, pp.
7–21, 2012.
ista: Eggermann E, Bucurenciu I, Goswami S, Jonas PM. 2012. Nanodomain coupling
between Ca(2+) channels and sensors of exocytosis at fast mammalian synapses.
Nature Reviews Neuroscience. 13(1), 7–21.
mla: Eggermann, Emmanuel, et al. “Nanodomain Coupling between Ca(2+) Channels and
Sensors of Exocytosis at Fast Mammalian Synapses.” Nature Reviews Neuroscience,
vol. 13, no. 1, Nature Publishing Group, 2012, pp. 7–21, doi:10.1038/nrn3125.
short: E. Eggermann, I. Bucurenciu, S. Goswami, P.M. Jonas, Nature Reviews Neuroscience
13 (2012) 7–21.
corr_author: '1'
date_created: 2018-12-11T12:02:38Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2025-09-30T07:34:43Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1038/nrn3125
external_id:
isi:
- '000298323200008'
file:
- access_level: open_access
checksum: 4c1c86b2f6e4e1562f5bb800b457ea9f
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:13Z
date_updated: 2020-07-14T12:46:07Z
file_id: '4931'
file_name: IST-2017-820-v1+1_17463_3_art_file_109404_ltmxbw.pdf
file_size: 314246
relation: main_file
- access_level: open_access
checksum: bceb2efdd49d115f4dde8486bc1be3f2
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:12:14Z
date_updated: 2020-07-14T12:46:07Z
file_id: '4932'
file_name: IST-2017-820-v1+2_17463_3_figure_109402_ltmwlp.pdf
file_size: 1840216
relation: main_file
file_date_updated: 2020-07-14T12:46:07Z
has_accepted_license: '1'
intvolume: ' 13'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 7 - 21
project:
- _id: 25BC64A8-B435-11E9-9278-68D0E5697425
grant_number: JO_780/A5
name: Synaptic Mechanisms of Neuronal Network Function
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Nature Reviews Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '3322'
pubrep_id: '820'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nanodomain coupling between Ca(2+) channels and sensors of exocytosis at fast
mammalian synapses
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 13
year: '2012'
...
---
_id: '2954'
abstract:
- lang: eng
text: Spontaneous postsynaptic currents (PSCs) provide key information about the
mechanisms of synaptic transmission and the activity modes of neuronal networks.
However, detecting spontaneous PSCs in vitro and in vivo has been challenging,
because of the small amplitude, the variable kinetics, and the undefined time
of generation of these events. Here, we describe a, to our knowledge, new method
for detecting spontaneous synaptic events by deconvolution, using a template that
approximates the average time course of spontaneous PSCs. A recorded PSC trace
is deconvolved from the template, resulting in a series of delta-like functions.
The maxima of these delta-like events are reliably detected, revealing the precise
onset times of the spontaneous PSCs. Among all detection methods, the deconvolution-based
method has a unique temporal resolution, allowing the detection of individual
events in high-frequency bursts. Furthermore, the deconvolution-based method has
a high amplitude resolution, because deconvolution can substantially increase
the signal/noise ratio. When tested against previously published methods using
experimental data, the deconvolution-based method was superior for spontaneous
PSCs recorded in vivo. Using the high-resolution deconvolution-based detection
algorithm, we show that the frequency of spontaneous excitatory postsynaptic currents
in dentate gyrus granule cells is 4.5 times higher in vivo than in vitro.
acknowledgement: "This work was supported by the Deutsche Forschungsgemeinschaft (TR3/B10)
and a European Research Council Advanced grant to P.J.\r\nWe thank H. Hu, S. J.
Guzman, and C. Schmidt-Hieber for critically reading the manuscript, I. Koeva and
F. Marr for technical support, and E. Kramberger for editorial assistance.\r\n"
article_processing_charge: No
author:
- first_name: Alejandro
full_name: Pernia-Andrade, Alejandro
id: 36963E98-F248-11E8-B48F-1D18A9856A87
last_name: Pernia-Andrade
- first_name: Sarit
full_name: Goswami, Sarit
id: 3A578F32-F248-11E8-B48F-1D18A9856A87
last_name: Goswami
- first_name: Yvonne
full_name: Stickler, Yvonne
id: 63B76600-E9CC-11E9-9B5F-82450873F7A1
last_name: Stickler
- first_name: Ulrich
full_name: Fröbe, Ulrich
last_name: Fröbe
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Pernia-Andrade A, Goswami S, Stickler Y, Fröbe U, Schlögl A, Jonas PM. A deconvolution
based method with high sensitivity and temporal resolution for detection of spontaneous
synaptic currents in vitro and in vivo. Biophysical Journal. 2012;103(7):1429-1439.
doi:10.1016/j.bpj.2012.08.039
apa: Pernia-Andrade, A., Goswami, S., Stickler, Y., Fröbe, U., Schlögl, A., &
Jonas, P. M. (2012). A deconvolution based method with high sensitivity and temporal
resolution for detection of spontaneous synaptic currents in vitro and in vivo.
Biophysical Journal. Biophysical Society. https://doi.org/10.1016/j.bpj.2012.08.039
chicago: Pernia-Andrade, Alejandro, Sarit Goswami, Yvonne Stickler, Ulrich Fröbe,
Alois Schlögl, and Peter M Jonas. “A Deconvolution Based Method with High Sensitivity
and Temporal Resolution for Detection of Spontaneous Synaptic Currents in Vitro
and in Vivo.” Biophysical Journal. Biophysical Society, 2012. https://doi.org/10.1016/j.bpj.2012.08.039.
ieee: A. Pernia-Andrade, S. Goswami, Y. Stickler, U. Fröbe, A. Schlögl, and P. M.
Jonas, “A deconvolution based method with high sensitivity and temporal resolution
for detection of spontaneous synaptic currents in vitro and in vivo,” Biophysical
Journal, vol. 103, no. 7. Biophysical Society, pp. 1429–1439, 2012.
ista: Pernia-Andrade A, Goswami S, Stickler Y, Fröbe U, Schlögl A, Jonas PM. 2012.
A deconvolution based method with high sensitivity and temporal resolution for
detection of spontaneous synaptic currents in vitro and in vivo. Biophysical Journal.
103(7), 1429–1439.
mla: Pernia-Andrade, Alejandro, et al. “A Deconvolution Based Method with High Sensitivity
and Temporal Resolution for Detection of Spontaneous Synaptic Currents in Vitro
and in Vivo.” Biophysical Journal, vol. 103, no. 7, Biophysical Society,
2012, pp. 1429–39, doi:10.1016/j.bpj.2012.08.039.
short: A. Pernia-Andrade, S. Goswami, Y. Stickler, U. Fröbe, A. Schlögl, P.M. Jonas,
Biophysical Journal 103 (2012) 1429–1439.
corr_author: '1'
das_tickbox: '1'
date_created: 2018-12-11T12:00:32Z
date_published: 2012-10-03T00:00:00Z
date_updated: 2026-07-06T12:32:51Z
day: '03'
department:
- _id: PeJo
- _id: ScienComp
doi: 10.1016/j.bpj.2012.08.039
external_id:
isi:
- '000309571400005'
pmid:
- '23062335'
intvolume: ' 103'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471482/
month: '10'
oa: 1
oa_version: Submitted Version
page: 1429 - 1439
pmid: 1
project:
- _id: 25BDE9A4-B435-11E9-9278-68D0E5697425
grant_number: SFB-TR3-TP10B
name: "Glutamaterge synaptische Ã\x9Cbertragung und Plastizität in hippocampalen
Mikroschaltkreisen"
publication: Biophysical Journal
publication_status: published
publisher: Biophysical Society
publist_id: '3774'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A deconvolution based method with high sensitivity and temporal resolution
for detection of spontaneous synaptic currents in vitro and in vivo
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 103
year: '2012'
...
---
_id: '469'
abstract:
- lang: eng
text: 'Spontaneous release of glutamate is important for maintaining synaptic strength
and controlling spike timing in the brain. Mechanisms regulating spontaneous exocytosis
remain poorly understood. Extracellular calcium concentration ([Ca2+]o) regulates
Ca2+ entry through voltage-activated calcium channels (VACCs) and consequently
is a pivotal determinant of action potential-evoked vesicle fusion. Extracellular
Ca 2+ also enhances spontaneous release, but via unknown mechanisms. Here we report
that external Ca2+ triggers spontaneous glutamate release more weakly than evoked
release in mouse neocortical neurons. Blockade of VACCs has no effect on the spontaneous
release rate or its dependence on [Ca2+]o. Intracellular [Ca2+] slowly increases
in a minority of neurons following increases in [Ca2+]o. Furthermore, the enhancement
of spontaneous release by extracellular calcium is insensitive to chelation of
intracellular calcium by BAPTA. Activation of the calcium-sensing receptor (CaSR),
a G-protein-coupled receptor present in nerve terminals, by several specific agonists
increased spontaneous glutamate release. The frequency of spontaneous synaptic
transmission was decreased in CaSR mutant neurons. The concentration-effect relationship
for extracellular calcium regulation of spontaneous release was well described
by a combination of CaSR-dependent and CaSR-independent mechanisms. Overall these
results indicate that extracellular Ca2+ does not trigger spontaneous glutamate
release by simply increasing calcium influx but stimulates CaSR and thereby promotes
resting spontaneous glutamate release. '
article_processing_charge: No
author:
- first_name: Nicholas
full_name: Vyleta, Nicholas
id: 36C4978E-F248-11E8-B48F-1D18A9856A87
last_name: Vyleta
- first_name: Stephen
full_name: Smith, Stephen
last_name: Smith
citation:
ama: Vyleta N, Smith S. Spontaneous glutamate release is independent of calcium
influx and tonically activated by the calcium-sensing receptor. European Journal
of Neuroscience. 2011;31(12):4593-4606. doi:10.1523/JNEUROSCI.6398-10.2011
apa: Vyleta, N., & Smith, S. (2011). Spontaneous glutamate release is independent
of calcium influx and tonically activated by the calcium-sensing receptor. European
Journal of Neuroscience. Wiley-Blackwell. https://doi.org/10.1523/JNEUROSCI.6398-10.2011
chicago: Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is
Independent of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.”
European Journal of Neuroscience. Wiley-Blackwell, 2011. https://doi.org/10.1523/JNEUROSCI.6398-10.2011.
ieee: N. Vyleta and S. Smith, “Spontaneous glutamate release is independent of calcium
influx and tonically activated by the calcium-sensing receptor,” European Journal
of Neuroscience, vol. 31, no. 12. Wiley-Blackwell, pp. 4593–4606, 2011.
ista: Vyleta N, Smith S. 2011. Spontaneous glutamate release is independent of calcium
influx and tonically activated by the calcium-sensing receptor. European Journal
of Neuroscience. 31(12), 4593–4606.
mla: Vyleta, Nicholas, and Stephen Smith. “Spontaneous Glutamate Release Is Independent
of Calcium Influx and Tonically Activated by the Calcium-Sensing Receptor.” European
Journal of Neuroscience, vol. 31, no. 12, Wiley-Blackwell, 2011, pp. 4593–606,
doi:10.1523/JNEUROSCI.6398-10.2011.
short: N. Vyleta, S. Smith, European Journal of Neuroscience 31 (2011) 4593–4606.
date_created: 2018-12-11T11:46:39Z
date_published: 2011-03-23T00:00:00Z
date_updated: 2025-09-30T09:25:10Z
day: '23'
department:
- _id: PeJo
doi: 10.1523/JNEUROSCI.6398-10.2011
external_id:
isi:
- '000288750700025'
intvolume: ' 31'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097128/
month: '03'
oa: 1
oa_version: Submitted Version
page: 4593 - 4606
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7353'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spontaneous glutamate release is independent of calcium influx and tonically
activated by the calcium-sensing receptor
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 31
year: '2011'
...
---
_id: '490'
abstract:
- lang: eng
text: 'BioSig is an open source software library for biomedical signal processing.
The aim of the BioSig project is to foster research in biomedical signal processing
by providing free and open source software tools for many different application
areas. Some of the areas where BioSig can be employed are neuroinformatics, brain-computer
interfaces, neurophysiology, psychology, cardiovascular systems, and sleep research.
Moreover, the analysis of biosignals such as the electroencephalogram (EEG), electrocorticogram
(ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG),
or respiration signals is a very relevant element of the BioSig project. Specifically,
BioSig provides solutions for data acquisition, artifact processing, quality control,
feature extraction, classification, modeling, and data visualization, to name
a few. In this paper, we highlight several methods to help students and researchers
to work more efficiently with biomedical signals. '
article_number: '935364'
article_processing_charge: No
author:
- first_name: Alois
full_name: Schlögl, Alois
id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
last_name: Schlögl
orcid: 0000-0002-5621-8100
- first_name: Carmen
full_name: Vidaurre, Carmen
last_name: Vidaurre
- first_name: Tilmann
full_name: Sander, Tilmann
last_name: Sander
citation:
ama: 'Schlögl A, Vidaurre C, Sander T. BioSig: The free and open source software
library for biomedical signal processing. Computational Intelligence and Neuroscience.
2011;2011. doi:10.1155/2011/935364'
apa: 'Schlögl, A., Vidaurre, C., & Sander, T. (2011). BioSig: The free and open
source software library for biomedical signal processing. Computational Intelligence
and Neuroscience. Hindawi Publishing Corporation. https://doi.org/10.1155/2011/935364'
chicago: 'Schlögl, Alois, Carmen Vidaurre, and Tilmann Sander. “BioSig: The Free
and Open Source Software Library for Biomedical Signal Processing.” Computational
Intelligence and Neuroscience. Hindawi Publishing Corporation, 2011. https://doi.org/10.1155/2011/935364.'
ieee: 'A. Schlögl, C. Vidaurre, and T. Sander, “BioSig: The free and open source
software library for biomedical signal processing,” Computational Intelligence
and Neuroscience, vol. 2011. Hindawi Publishing Corporation, 2011.'
ista: 'Schlögl A, Vidaurre C, Sander T. 2011. BioSig: The free and open source software
library for biomedical signal processing. Computational Intelligence and Neuroscience.
2011, 935364.'
mla: 'Schlögl, Alois, et al. “BioSig: The Free and Open Source Software Library
for Biomedical Signal Processing.” Computational Intelligence and Neuroscience,
vol. 2011, 935364, Hindawi Publishing Corporation, 2011, doi:10.1155/2011/935364.'
short: A. Schlögl, C. Vidaurre, T. Sander, Computational Intelligence and Neuroscience
2011 (2011).
corr_author: '1'
date_created: 2018-12-11T11:46:45Z
date_published: 2011-01-01T00:00:00Z
date_updated: 2025-09-30T09:24:43Z
day: '01'
ddc:
- '005'
department:
- _id: ScienComp
- _id: PeJo
doi: 10.1155/2011/935364
external_id:
isi:
- '000208906100033'
file:
- access_level: open_access
checksum: 8263bbf255171f2054f43f3db5f53b6e
content_type: application/pdf
creator: system
date_created: 2018-12-12T10:07:44Z
date_updated: 2020-07-14T12:46:35Z
file_id: '4642'
file_name: IST-2018-947-v1+1_2011_Schloegl_BioSig.pdf
file_size: 2863551
relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
has_accepted_license: '1'
intvolume: ' 2011'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: Computational Intelligence and Neuroscience
publication_status: published
publisher: Hindawi Publishing Corporation
publist_id: '7330'
pubrep_id: '947'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'BioSig: The free and open source software library for biomedical signal processing'
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 2011
year: '2011'
...
---
_id: '3318'
abstract:
- lang: eng
text: Parvalbumin is thought to act in a manner similar to EGTA, but how a slow
Ca2+ buffer affects nanodomain-coupling regimes at GABAergic synapses is unclear.
Direct measurements of parvalbumin concentration and paired recordings in rodent
hippocampus and cerebellum revealed that parvalbumin affects synaptic dynamics
only when expressed at high levels. Modeling suggests that, in high concentrations,
parvalbumin may exert BAPTA-like effects, modulating nanodomain coupling via competition
with local saturation of endogenous fixed buffers.
article_processing_charge: No
author:
- first_name: Emmanuel
full_name: Eggermann, Emmanuel
last_name: Eggermann
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Eggermann E, Jonas PM. How the “slow” Ca(2+) buffer parvalbumin affects transmitter
release in nanodomain coupling regimes at GABAergic synapses. Nature Neuroscience.
2011;15:20-22. doi:10.1038/nn.3002
apa: Eggermann, E., & Jonas, P. M. (2011). How the “slow” Ca(2+) buffer parvalbumin
affects transmitter release in nanodomain coupling regimes at GABAergic synapses.
Nature Neuroscience. Nature Publishing Group. https://doi.org/10.1038/nn.3002
chicago: Eggermann, Emmanuel, and Peter M Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin
Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.”
Nature Neuroscience. Nature Publishing Group, 2011. https://doi.org/10.1038/nn.3002.
ieee: E. Eggermann and P. M. Jonas, “How the ‘slow’ Ca(2+) buffer parvalbumin affects
transmitter release in nanodomain coupling regimes at GABAergic synapses,” Nature
Neuroscience, vol. 15. Nature Publishing Group, pp. 20–22, 2011.
ista: Eggermann E, Jonas PM. 2011. How the “slow” Ca(2+) buffer parvalbumin affects
transmitter release in nanodomain coupling regimes at GABAergic synapses. Nature
Neuroscience. 15, 20–22.
mla: Eggermann, Emmanuel, and Peter M. Jonas. “How the ‘Slow’ Ca(2+) Buffer Parvalbumin
Affects Transmitter Release in Nanodomain Coupling Regimes at GABAergic Synapses.”
Nature Neuroscience, vol. 15, Nature Publishing Group, 2011, pp. 20–22,
doi:10.1038/nn.3002.
short: E. Eggermann, P.M. Jonas, Nature Neuroscience 15 (2011) 20–22.
corr_author: '1'
date_created: 2018-12-11T12:02:38Z
date_published: 2011-12-04T00:00:00Z
date_updated: 2025-09-30T09:20:05Z
day: '04'
department:
- _id: PeJo
doi: 10.1038/nn.3002
external_id:
isi:
- '000298414400008'
intvolume: ' 15'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631701/
month: '12'
oa: 1
oa_version: Submitted Version
page: 20 - 22
publication: Nature Neuroscience
publication_status: published
publisher: Nature Publishing Group
publist_id: '3321'
quality_controlled: '1'
scopus_import: '1'
status: public
title: How the “slow” Ca(2+) buffer parvalbumin affects transmitter release in nanodomain
coupling regimes at GABAergic synapses
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 15
year: '2011'
...
---
_id: '3369'
abstract:
- lang: eng
text: Rab3 interacting molecules (RIMs) are highly enriched in the active zones
of presynaptic terminals. It is generally thought that they operate as effectors
of the small G protein Rab3. Three recent papers, by Han et al. (this issue of
Neuron), Deng et al. (this issue of Neuron), and Kaeser et al. (a recent issue
of Cell), shed new light on the functional role of RIM in presynaptic terminals.
First, RIM tethers Ca2+ channels to active zones. Second, RIM contributes to priming
of synaptic vesicles by interacting with another presynaptic protein, Munc13.
article_processing_charge: No
author:
- first_name: Alejandro
full_name: Pernia-Andrade, Alejandro
id: 36963E98-F248-11E8-B48F-1D18A9856A87
last_name: Pernia-Andrade
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Pernia-Andrade A, Jonas PM. The multiple faces of RIM. Neuron. 2011;69(2):185-187.
doi:10.1016/j.neuron.2011.01.010
apa: Pernia-Andrade, A., & Jonas, P. M. (2011). The multiple faces of RIM. Neuron.
Elsevier. https://doi.org/10.1016/j.neuron.2011.01.010
chicago: Pernia-Andrade, Alejandro, and Peter M Jonas. “The Multiple Faces of RIM.”
Neuron. Elsevier, 2011. https://doi.org/10.1016/j.neuron.2011.01.010.
ieee: A. Pernia-Andrade and P. M. Jonas, “The multiple faces of RIM,” Neuron,
vol. 69, no. 2. Elsevier, pp. 185–187, 2011.
ista: Pernia-Andrade A, Jonas PM. 2011. The multiple faces of RIM. Neuron. 69(2),
185–187.
mla: Pernia-Andrade, Alejandro, and Peter M. Jonas. “The Multiple Faces of RIM.”
Neuron, vol. 69, no. 2, Elsevier, 2011, pp. 185–87, doi:10.1016/j.neuron.2011.01.010.
short: A. Pernia-Andrade, P.M. Jonas, Neuron 69 (2011) 185–187.
corr_author: '1'
date_created: 2018-12-11T12:02:56Z
date_published: 2011-01-27T00:00:00Z
date_updated: 2025-09-30T09:01:26Z
day: '27'
department:
- _id: PeJo
doi: 10.1016/j.neuron.2011.01.010
external_id:
isi:
- '000286792900002'
intvolume: ' 69'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa_version: None
page: 185 - 187
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '3243'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The multiple faces of RIM
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 69
year: '2011'
...
---
_id: '3718'
abstract:
- lang: eng
text: Long-term depression (LTD) is a form of synaptic plasticity that may contribute
to information storage in the central nervous system. Here we report that LTD
can be elicited in layer 5 pyramidal neurons of the rat prefrontal cortex by pairing
low frequency stimulation with a modest postsynaptic depolarization. The induction
of LTD required the activation of both metabotropic glutamate receptors of the
mGlu1 subtype and voltage-sensitive Ca(2+) channels (VSCCs) of the T/R, P/Q and
N types, leading to the stimulation of intracellular inositol trisphosphate (IP3)
receptors by IP3 and Ca(2+). The subsequent release of Ca(2+) from intracellular
stores activated the protein phosphatase cascade involving calcineurin and protein
phosphatase 1. The activation of purinergic P2Y(1) receptors blocked LTD. This
effect was prevented by P2Y(1) receptor antagonists and was absent in mice lacking
P2Y(1) but not P2Y(2) receptors. We also found that activation of P2Y(1) receptors
inhibits Ca(2+) transients via VSCCs in the apical dendrites and spines of pyramidal
neurons. In addition, we show that the release of ATP under hypoxia is able to
inhibit LTD by acting on postsynaptic P2Y(1) receptors. In conclusion, these data
suggest that the reduction of Ca(2+) influx via VSCCs caused by the activation
of P2Y(1) receptors by ATP is the possible mechanism for the inhibition of LTD
in prefrontal cortex.
acknowledgement: " The financial support of the Deutsche Forschungsgemeinschaft (IL
20/12-1, KI 677/2-4) is gratefully acknowledged.\r\nWe thank B. H. Koller (Department
of Genetics and Molecular Biology, University of North Carolina at Chapel Hill,
NC, USA) for the generous supply of P2Y1−/− and P2Y2−/− mice. We are grateful to
Dr. A. Schulz for reanalysing the genotype of the P2Y1−/− mice. The authors thank
P. Jonas and U. Heinemann for many helpful comments and A-K. Krause, L Feige and
M. Eberts for their excellent technical support."
article_processing_charge: No
author:
- first_name: José
full_name: Guzmán, José
id: 30CC5506-F248-11E8-B48F-1D18A9856A87
last_name: Guzmán
orcid: 0000-0003-2209-5242
- first_name: Hartmut
full_name: Schmidt, Hartmut
last_name: Schmidt
- first_name: Heike
full_name: Franke, Heike
last_name: Franke
- first_name: Ute
full_name: Krügel, Ute
last_name: Krügel
- first_name: Jens
full_name: Eilers, Jens
last_name: Eilers
- first_name: Peter
full_name: Illes, Peter
last_name: Illes
- first_name: Zoltan
full_name: Gerevich, Zoltan
last_name: Gerevich
citation:
ama: Guzmán J, Schmidt H, Franke H, et al. P2Y1 receptors inhibit long-term depression
in the prefrontal cortex. Neuropharmacology. 2010;59(6):406-415. doi:10.1016/j.neuropharm.2010.05.013
apa: Guzmán, J., Schmidt, H., Franke, H., Krügel, U., Eilers, J., Illes, P., &
Gerevich, Z. (2010). P2Y1 receptors inhibit long-term depression in the prefrontal
cortex. Neuropharmacology. Elsevier. https://doi.org/10.1016/j.neuropharm.2010.05.013
chicago: Guzmán, José, Hartmut Schmidt, Heike Franke, Ute Krügel, Jens Eilers, Peter
Illes, and Zoltan Gerevich. “P2Y1 Receptors Inhibit Long-Term Depression in the
Prefrontal Cortex.” Neuropharmacology. Elsevier, 2010. https://doi.org/10.1016/j.neuropharm.2010.05.013.
ieee: J. Guzmán et al., “P2Y1 receptors inhibit long-term depression in the
prefrontal cortex.,” Neuropharmacology, vol. 59, no. 6. Elsevier, pp. 406–415,
2010.
ista: Guzmán J, Schmidt H, Franke H, Krügel U, Eilers J, Illes P, Gerevich Z. 2010.
P2Y1 receptors inhibit long-term depression in the prefrontal cortex. Neuropharmacology.
59(6), 406–415.
mla: Guzmán, José, et al. “P2Y1 Receptors Inhibit Long-Term Depression in the Prefrontal
Cortex.” Neuropharmacology, vol. 59, no. 6, Elsevier, 2010, pp. 406–15,
doi:10.1016/j.neuropharm.2010.05.013.
short: J. Guzmán, H. Schmidt, H. Franke, U. Krügel, J. Eilers, P. Illes, Z. Gerevich,
Neuropharmacology 59 (2010) 406–415.
corr_author: '1'
date_created: 2018-12-11T12:04:47Z
date_published: 2010-11-01T00:00:00Z
date_updated: 2025-09-30T09:46:27Z
day: '01'
department:
- _id: PeJo
doi: 10.1016/j.neuropharm.2010.05.013
external_id:
isi:
- '000283453300006'
intvolume: ' 59'
isi: 1
issue: '6'
language:
- iso: eng
month: '11'
oa_version: None
page: 406 - 415
publication: Neuropharmacology
publication_status: published
publisher: Elsevier
publist_id: '2512'
quality_controlled: '1'
scopus_import: '1'
status: public
title: P2Y1 receptors inhibit long-term depression in the prefrontal cortex.
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 59
year: '2010'
...
---
_id: '3832'
abstract:
- lang: eng
text: A recent paper by von Engelhardt et al. identifies a novel auxiliary subunit
of native AMPARs, termedCKAMP44. Unlike other auxiliary subunits, CKAMP44 accelerates
desensitization and prolongs recovery from desensitization. CKAMP44 is highly
expressed in hippocampal dentate gyrus granule cells and decreases the paired-pulse
ratio at perforant path input synapses. Thus, both principal and auxiliary AMPAR
subunits control the time course of signaling at glutamatergic synapses.
article_processing_charge: No
author:
- first_name: José
full_name: Guzmán, José
id: 30CC5506-F248-11E8-B48F-1D18A9856A87
last_name: Guzmán
orcid: 0000-0003-2209-5242
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Guzmán J, Jonas PM. Beyond TARPs: The growing list of auxiliary AMPAR subunits.
Neuron. 2010;66(1):8-10. doi:10.1016/j.neuron.2010.04.003'
apa: 'Guzmán, J., & Jonas, P. M. (2010). Beyond TARPs: The growing list of auxiliary
AMPAR subunits. Neuron. Elsevier. https://doi.org/10.1016/j.neuron.2010.04.003'
chicago: 'Guzmán, José, and Peter M Jonas. “Beyond TARPs: The Growing List of Auxiliary
AMPAR Subunits.” Neuron. Elsevier, 2010. https://doi.org/10.1016/j.neuron.2010.04.003.'
ieee: 'J. Guzmán and P. M. Jonas, “Beyond TARPs: The growing list of auxiliary AMPAR
subunits,” Neuron, vol. 66, no. 1. Elsevier, pp. 8–10, 2010.'
ista: 'Guzmán J, Jonas PM. 2010. Beyond TARPs: The growing list of auxiliary AMPAR
subunits. Neuron. 66(1), 8–10.'
mla: 'Guzmán, José, and Peter M. Jonas. “Beyond TARPs: The Growing List of Auxiliary
AMPAR Subunits.” Neuron, vol. 66, no. 1, Elsevier, 2010, pp. 8–10, doi:10.1016/j.neuron.2010.04.003.'
short: J. Guzmán, P.M. Jonas, Neuron 66 (2010) 8–10.
corr_author: '1'
date_created: 2018-12-11T12:05:25Z
date_published: 2010-04-15T00:00:00Z
date_updated: 2026-06-18T18:47:22Z
day: '15'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.neuron.2010.04.003
external_id:
isi:
- '000277016200004'
pmid:
- '20399724'
intvolume: ' 66'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pubmed/20399724
month: '04'
oa: 1
oa_version: Published Version
page: 8 - 10
pmid: 1
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '2377'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Beyond TARPs: The growing list of auxiliary AMPAR subunits'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 66
year: '2010'
...
---
_id: '3833'
article_processing_charge: No
author:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Stefan
full_name: Hefft, Stefan
last_name: Hefft
citation:
ama: 'Jonas PM, Hefft S. GABA release at terminals of CCK-interneurons: Synchrony,
asynchrony and modulation by cannabinoid receptors (commentary on Ali &
Todorova). The European Journal of Neuroscience. 2010;31(7):1194-1195.
doi:10.1111/j.1460-9568.2010.07189.x'
apa: 'Jonas, P. M., & Hefft, S. (2010). GABA release at terminals of CCK-interneurons:
Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali
& Todorova). The European Journal of Neuroscience. Wiley-Blackwell.
https://doi.org/10.1111/j.1460-9568.2010.07189.x'
chicago: 'Jonas, Peter M, and Stefan Hefft. “GABA Release at Terminals of CCK-Interneurons:
Synchrony, Asynchrony and Modulation by Cannabinoid Receptors (Commentary on Ali
& Todorova).” The European Journal of Neuroscience. Wiley-Blackwell,
2010. https://doi.org/10.1111/j.1460-9568.2010.07189.x.'
ieee: 'P. M. Jonas and S. Hefft, “GABA release at terminals of CCK-interneurons:
Synchrony, asynchrony and modulation by cannabinoid receptors (commentary on Ali
& Todorova),” The European Journal of Neuroscience, vol. 31, no.
7. Wiley-Blackwell, pp. 1194–1195, 2010.'
ista: 'Jonas PM, Hefft S. 2010. GABA release at terminals of CCK-interneurons: Synchrony,
asynchrony and modulation by cannabinoid receptors (commentary on Ali &
Todorova). The European Journal of Neuroscience. 31(7), 1194–1195.'
mla: 'Jonas, Peter M., and Stefan Hefft. “GABA Release at Terminals of CCK-Interneurons:
Synchrony, Asynchrony and Modulation by Cannabinoid Receptors (Commentary on Ali
& Todorova).” The European Journal of Neuroscience, vol. 31, no.
7, Wiley-Blackwell, 2010, pp. 1194–95, doi:10.1111/j.1460-9568.2010.07189.x.'
short: P.M. Jonas, S. Hefft, The European Journal of Neuroscience 31 (2010) 1194–1195.
corr_author: '1'
date_created: 2018-12-11T12:05:25Z
date_published: 2010-03-19T00:00:00Z
date_updated: 2025-09-30T09:38:44Z
day: '19'
department:
- _id: PeJo
doi: 10.1111/j.1460-9568.2010.07189.x
external_id:
isi:
- '000276245400005'
intvolume: ' 31'
isi: 1
issue: '7'
language:
- iso: eng
month: '03'
oa_version: None
page: 1194 - 1195
publication: The European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2378'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'GABA release at terminals of CCK-interneurons: Synchrony, asynchrony and modulation
by cannabinoid receptors (commentary on Ali & Todorova)'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 31
year: '2010'
...