@article{21714, abstract = {Be stars are rapidly rotating main-sequence stars that play a crucial role in understanding stellar evolution and binary interactions. In this Letter, we propose a new formation scenario for black hole (BH) + Be star binaries (hereafter BHBe binaries), where the Be star is produced through the wind Roche lobe overflow (WRLOF) mechanism. Our analysis is based on numerical simulations of the WRLOF process in massive binaries, building on recent theoretical work. We demonstrate that the WRLOF model can efficiently form BHBe binaries under reasonable assumptions on stellar wind velocities. Using rapid binary population synthesis, we estimate the population of such systems in the Milky Way, predicting ∼1800−3200 currently existing BHBe binaries originating from the WRLOF channel. These systems are characterized by high eccentricities and exceptionally wide orbits, with typical orbital periods exceeding 1000 days and a peak distribution around ∼10,000 days. Due to their long orbital separations, these BHBe binaries are promising targets for future detection via astrometric and interferometric observations.}, author = {Li, Zhenwei and Jia, Shi and Wei, Dandan and Ge, Hongwei and Chen, Hailiang and Zhang, Yangyang and Chen, Xuefei and Han, Zhanwen}, issn = {2041-8213}, journal = {The Astrophysical Journal Letters}, number = {2}, publisher = {IOP Publishing}, title = {{Formation of Be stars via wind accretion: Case study on Black Hole + Be star binaries}}, doi = {10.3847/2041-8213/ae3008}, volume = {996}, year = {2026}, } @article{21715, abstract = {New populations of red active galactic nuclei (known as “little red dots”) discovered by JWST exhibit remarkable spectral energy distributions. Leveraging X-ray through far-infrared observations of two of the most luminous known little red dots, we directly measure their bolometric luminosities. We find evidence that more than half of the bolometric luminosity likely emerges in the rest-frame optical, with Lbol/L5100 = 5, roughly half the value for “standard” active galactic nuclei. Meanwhile, the X-ray emitting corona, UV-emitting blackbody, and reprocessed mid to far-infrared emission are all considerably subdominant, assuming that the far-infrared luminosity is well below current measured limits. We present new bolometric corrections that dramatically lower inferred bolometric luminosities by a factor of 10 compared to published values in the literature. These bolometric corrections are in accord with expectations from models in which gas absorption and reprocessing are responsible for the red rest-frame optical colors of little red dots. We discuss how this lowered luminosity scale suggests a lower mass scale for the population by at least an order of magnitude (e.g., ∼105–107 M⊙ black holes, and ∼108 M⊙ galaxies), alleviating tensions with clustering, overmassive black holes, and the integrated black hole mass density in the Universe.}, author = {Greene, Jenny E. and Setton, David J. and Furtak, Lukas J. and Naidu, Rohan P. and Volonteri, Marta and Dayal, Pratika and Labbe, Ivo and Van Dokkum, Pieter and Bezanson, Rachel and Brammer, Gabriel and Cutler, Sam E. and Glazebrook, Karl and De Graaff, Anna and Hirschmann, Michaela and Hviding, Raphael E. and Kokorev, Vasily and Leja, Joel and Liu, Hanpu and Ma, Yilun and Matthee, Jorryt J and Nanayakkara, Themiya and Oesch, Pascal A. and Pan, Richard and Price, Sedona H. and Spilker, Justin S. and Wang, Bingjie and Weaver, John R. and Whitaker, Katherine E. and Williams, Christina C. and Zitrin, Adi}, issn = {1538-4357}, journal = {The Astrophysical Journal}, number = {2}, publisher = {IOP Publishing}, title = {{What you see is what you get: Empirically measured bolometric luminosities of Little Red Dots}}, doi = {10.3847/1538-4357/ae1836}, volume = {996}, year = {2026}, } @article{21716, abstract = {Male germline development in plants is highly sensitive to heat stress, with elevated temperatures frequently impairing male fertility and consequently reducing seed production. Indeed, recent global warming has decreased major crop yields, emphasizing the urgent need to elucidate the molecular and cellular mechanisms underlying heat-induced male sterility. This review synthesizes current knowledge on how heat stress disrupts microsporogenesis and microgametogenesis, and how plants counteract these stresses through diverse thermotolerance mechanisms. We emphasize temperature-sensitive processes, including meiotic progression in male germ cells, programmed cell death of somatic tapetal nurse cells, and post-meiotic pollen tube development. We further discuss how epigenetic regulators enhance thermotolerance by reprogramming DNA methylation landscapes and modulating histone variant distribution. Finally, we propose future directions aimed at understanding the mechanisms of reproductive thermotolerance from the epigenetic perspective.}, author = {Nagai, Hiroki and Feng, Xiaoqi}, issn = {1879-0356}, journal = {Current Opinion in Plant Biology}, number = {6}, publisher = {Elsevier}, title = {{Genetic and epigenetic mechanisms underlying male reproductive thermotolerance}}, doi = {10.1016/j.pbi.2026.102881}, volume = {91}, year = {2026}, } @inproceedings{21717, abstract = {Robust Markov Decision Processes (RMDPs) generalize classical MDPs that consider uncertainties in transition probabilities by defining a set of possible transition functions. An objective is a set of runs (or infinite trajectories) of the RMDP, and the value for an objective is the maximal probability that the agent can guarantee against the adversarial environment. We consider (a) reachability objectives, where given a target set of states, the goal is to eventually arrive at one of them; and (b) parity objectives, which are a canonical representation for ω-regular objectives. The qualitative analysis problem asks whether the objective can be ensured with probability 1. In this work, we study the qualitative problem for reachability and parity objectives on RMDPs without making any assumption over the structures of the RMDPs, e.g., unichain or aperiodic. Our contributions are twofold. We first present efficient algorithms with oracle access to uncertainty sets that solve qualitative problems of reachability and parity objectives. We then report experimental results demonstrating the effectiveness of our oracle-based approach on classical RMDP examples from the literature scaling up to thousands of states.}, author = {Asadi, Ali and Chatterjee, Krishnendu and Kafshdar Goharshadi, Ehsan and Karrabi, Mehrdad and Shafiee, Ali}, booktitle = {Proceedings of the 40th AAAI Conference on Artificial Intelligence}, issn = {2374-3468}, location = {Singapore, Singapore}, number = {43}, pages = {36137--36145}, publisher = {Association for the Advancement of Artificial Intelligence}, title = {{Qualitative analysis of ω-regular objectives on robust MDPs}}, doi = {10.1609/aaai.v40i43.40931}, volume = {40}, year = {2026}, } @article{21718, abstract = {In this paper, we consider the big algebra recently introduced by Hausel for the GLn-action on the coordinate ring of the matrix space Mat(n,r). In particular, we obtain explicit formulas for the big algebra generators in terms of differential operators with polynomial coefficients. We show that big algebras in type A are commutative and relate them to the Bethe subalgebra in the Yangian Y(gln). We apply these results to big algebras of symmetric powers of the standard representation of GLn. .}, author = {Ngo, Nhok T}, issn = {1815-0659}, journal = {Symmetry, Integrability and Geometry: Methods and Applications}, publisher = {National Academy of Science of Ukraine}, title = {{Big algebra in type A for the coordinate ring of the matrix space}}, doi = {10.3842/SIGMA.2026.024}, volume = {22}, year = {2026}, } @inproceedings{21719, abstract = {We develop a new algorithmic framework for designing approximation algorithms for cut-based optimization problems on capacitated undirected graphs that undergo edge insertions and deletions. Specifically, our framework dynamically maintains a variant of the hierarchical 𝑗-tree decomposition of [Madry FOCS’10], achieving a poly-logarithmic approximation factor to the graph’s cut structure and supporting edge updates in 𝑂⁡(𝑛𝜀) amortized update time, for any arbitrarily small constant 𝜀 ∈(0,1). Consequently, we obtain new trade-offs between approximation and update/query time for fundamental cut-based optimization problems in the fully dynamic setting, including all-pairs minimum cuts, sparsest cut, multi-way cut, and multi-cut. For the last three problems, these trade-offs give the first fully-dynamic algorithms achieving poly-logarithmic approximation in sub-linear time per operation. The main technical ingredient behind our dynamic hierarchy is a dynamic cut-sparsifier algorithm that can handle vertex splits with low recourse. This is achieved by white-boxing the dynamic cut sparsifier construction of [Abraham et al. FOCS’16], based on forest packing, together with new structural insights about the maintenance of these forests under vertex splits. Given the versatility of cut sparsification in both the static and dynamic graph algorithms literature, we believe this construction may be of independent interest.}, author = {Goranci, Gramoz and Henzinger, Monika H and Kiss, Peter and Momeni, Ali and Zöcklein, Gernot}, booktitle = {Proceedings of the 2026 Annual ACM SIAM Symposium on Discrete Algorithms}, isbn = {9781611978971}, issn = {15579468}, pages = {1128--1180}, publisher = {Society for Industrial and Applied Mathematics}, title = {{Dynamic hierarchical j-tree decomposition and its applications}}, doi = {10.1137/1.9781611978971.45}, volume = {2026-January}, year = {2026}, } @inproceedings{21720, abstract = {We present an exact fully-dynamic minimum cut algorithm that runs in 𝑛𝑜⁡(1) deterministic update time when the minimum cut size is at most 2Θ⁡(log3/4−𝑐⁡𝑛) for any 𝑐 >0, improving on the previous algorithm of Jin, Sun, and Thorup (SODA 2024) whose minimum cut size limit is (log⁡𝑛)𝑜⁡(1). Combined with graph sparsification, we obtain the first (1 +𝜖)-approximate fully-dynamic minimum cut algorithm on weighted graphs, for any 𝜖 ≥2−Θ⁡(log3/4−𝑐⁡𝑛), in 𝑛𝑜⁡(1) randomized update time. Our main technical contribution is a deterministic local minimum cut algorithm, which replaces the randomized LocalKCut procedure from El-Hayek, Henzinger, and Li (SODA 2025).}, author = {El-Hayek, Antoine and Henzinger, Monika H and Li, Jason}, booktitle = {Proceedings of the Annual ACM SIAM Symposium on Discrete Algorithms}, issn = {1557-9468}, location = {Vancouver, Canada}, pages = {613--663}, publisher = {Society for Industrial and Applied Mathematics}, title = {{Deterministic and exact fully-dynamic minimum cut of superpolylogarithmic size in subpolynomial time}}, doi = {10.1137/1.9781611978971.25}, volume = {2026}, year = {2026}, } @article{21721, abstract = {Swimming bacteria move through a fluid by actuating their moving body parts. They are force-free and can be described as hydrodynamic force dipoles: pushers or pullers. This modelling description is broadly used in biological physics and active matter research, and it has successfully predicted, for example, the superfluid behaviour of suspensions of pushers or the bend instability and emergence of turbulent flows in active nematics. However, this description accounts only for the translational motion of the swimming body and neglects the effects of hydrodynamic torque dipoles, which are relevant to bacteria with rotary motor-driven flagella, such as swimming Escherichia coli. Here we show that the torque dipole of confined swimming E. coli can power the persistent rotation of symmetric discs. The torque dipole leads to a traction force on the discs, an additive mechanism that is both contactless and independent of the orientation of the bacteria. Our results indicate that the torque dipole of swimming E. coli is notable in confined geometries, which is relevant to bacterial transport through porous materials, biofilms and the development of chiral fluids.}, author = {Grober, Daniel B and Dhar, Tanumoy and Saintillan, David and Palacci, Jérémie A}, issn = {1745-2481}, journal = {Nature Physics}, publisher = {Springer Nature}, title = {{The hydrodynamic torque dipole from rotary bacterial flagella powers symmetric discs}}, doi = {10.1038/s41567-026-03189-4}, year = {2026}, } @inproceedings{21722, abstract = {Partially observable Markov decision processes (POMDPs) are a central model for uncertainty in sequential decision making. The most basic objective is the reachability objective, where a target set must be eventually visited, and the more general parity objectives can model all omega-regular specifications. For such objectives, the computational analysis problems are the following: (a) qualitative analysis that asks whether the objective can be satisfied with probability 1 (almost-sure winning) or probability arbitrarily close to 1 (limit-sure winning); and (b) quantitative analysis that asks for the approximation of the optimal probability of satisfying the objective. For general POMDPs, almost-sure analysis for reachability objectives is EXPTIME-complete, but limit-sure and quantitative analyses for reachability objectives are undecidable; almost-sure, limit-sure, and quantitative analyses for parity objectives are all undecidable. A special class of POMDPs, called revealing POMDPs, has been studied recently in several works, and for this subclass the almost-sure analysis for parity objectives was shown to be EXPTIME-complete. In this work, we show that for revealing POMDPs the limit-sure analysis for parity objectives is EXPTIME-complete, and even the quantitative analysis for parity objectives can be achieved in EXPTIME.}, author = {Asadi, Ali and Chatterjee, Krishnendu and Lurie, David and Saona Urmeneta, Raimundo J}, booktitle = {Proceedings of the AAAI Conference on Artificial Intelligence}, issn = {2374-3468}, location = {Singapore, Singapore}, number = {43}, pages = {36146--36154}, publisher = {Association for the Advancement of Artificial Intelligence}, title = {{Revealing POMDPs: Qualitative and quantitative analysis for parity objectives}}, doi = {10.1609/aaai.v40i43.40932}, volume = {40}, year = {2026}, } @article{21725, abstract = {The initial–final mass relation (IFMR) links a star’s birth mass to the mass of its white dwarf (WD) remnant, providing key constraints on stellar evolution. Open clusters offer the most straightforward way to empirically determine the IFMR, as their well-defined ages allow for direct progenitor lifetime estimates. We construct the most comprehensive open cluster WD IFMR to date by combining new spectroscopy of 22 WDs with an extensive literature review of WDs with strong cluster associations. To minimize systematics, we restrict our analysis to spectroscopically confirmed hydrogen-atmosphere (DA) WDs consistent with single-stellar origins. We separately analyze a subset with reliable Gaia-based astrometric membership assessments, as well as a full sample that adds WDs with strong cluster associations whose membership cannot be reliably assessed with Gaia. The Gaia-based sample includes 69 spectroscopically confirmed DA WDs, more than doubling the sample size of previous Gaia-based open cluster IFMRs. The full sample, which includes 53 additional literature WDs, increases the total number of cluster WDs by over 50% relative to earlier works. We provide functional forms for both the Gaia-based and full-sample IFMRs. The Gaia-based result useful for Mi � 2.67 M⊙ is Mf = [0.179 0.100H (Mi 3.84 M )] × (Mi 3.84 M ) + 0.628 M , where H(x) is the Heaviside step function. Comparing our IFMR to recent literature, we identify significant deviations from best-fit IFMRs derived from both Gaia-based volume-limited samples of field WDs and double WD binaries, with the largest discrepancy occurring for initial masses of about 5 M⊙.}, author = {Miller, David R. and Caiazzo, Ilaria and Heyl, Jeremy and Richer, Harvey B. and Hollands, Mark A. and Tremblay, Pier Emmanuel and El-Badry, Kareem and Rodriguez, Antonio C. and Vanderbosch, Zachary P.}, issn = {1538-4357}, journal = {The Astrophysical Journal}, keywords = {White dwarf stars, Open star clusters, Compact objects, Stellar evolution}, number = {1}, publisher = {IOP Publishing}, title = {{The White Dwarf initial–final mass relation from open clusters in Gaia DR3}}, doi = {10.3847/1538-4357/ae18c8}, volume = {996}, year = {2026}, } @article{21726, abstract = {Quantum control of the many-body wavefunction is a central challenge in quantum materials research, as it could yield a precise control knob to manipulate emergent phenomena. Floquet engineering, the coherent dressing of quantum states with periodic non-resonant optical fields, has become an important strategy for quantum control. Most applications to solid-state systems have targeted weakly interacting or single-ion states, leaving the manipulation of many-body wavefunctions largely unexplored. Here we use Floquet engineering to achieve quantum control of a strongly correlated Hubbard exciton in the one-dimensional Mott insulator Sr2CuO3. A non-resonant mid-infrared optical field coherently dresses the exciton wavefunction, driving its rotation between bright and dark states. We use resonant third-harmonic generation to quantify ultrafast π/2 rotations on the Bloch sphere spanned by these exciton states. Our work advances the quest towards programmable control of correlated states and exciton-based quantum sensing.}, author = {Baykusheva, Denitsa Rangelova and Carmichael, Deven and Weber, Clara S. and Lu, I. Te and Glerean, Filippo and Meng, Tepie and De Oliveira, Pedro B.M. and Homes, Christopher C. and Zaliznyak, Igor A. and Gu, G. D. and Dean, Mark P.M. and Rubio, Angel and Kennes, Dante M. and Claassen, Martin and Mitrano, Matteo}, issn = {1476-4660}, journal = {Nature Materials}, publisher = {Springer Nature}, title = {{Quantum control of Hubbard excitons}}, doi = {10.1038/s41563-026-02517-6}, year = {2026}, } @article{21730, abstract = {Hydrogen peroxide (H2O2) is a crucial member of the reactive oxygen species (ROS) family, playing roles in cellular signalling and immune responses in human health. Moreover, it is a potential biomarker of diabetes when present in aberrant concentrations. Therefore, monitoring trace levels of H2O2 has become a research hotspot for analytical and sensor chemists. In this context, we report a rhodamine-based fluorescent probe (RN), which shows excellent fluorescent enhancement at 555 nm upon the addition of H2O2 along with a low limit of detection (LOD) of 0.67 ppm and fast response (∼2 min). The probe is highly selective for H2O2, showing no fluorescence enhancement with other ROS. RN is synthesised in a one-pot chemical reaction using rhodamine 6G (R6G) and 4,7,10-trioxa-1,13-tridecanediamine (TTDA). H2O2 detection in pre-treated milk samples proves its real-world viability. We found that RN shows low cytotoxicity, which allowed us to successfully explore its potential to monitor H2O2 generation in a diabetic L929 skin cell line and diabetic mice liver tissue. This result demonstrates promising features for assessing early diabetic progression through fluorescence imaging.}, author = {Mondal, Moumita and Ghorai, Pravat and Samadder, Asmita and Freunberger, Stefan Alexander and Banerjee, Priyabrata}, issn = {2050-7518}, journal = {Journal of Materials Chemistry B}, publisher = {Royal Society of Chemistry}, title = {{H2O2 responsive rhodamine-based probe for monitoring early-stage diabetes diagnosis}}, doi = {10.1039/d5tb02687c}, year = {2026}, } @unpublished{21737, abstract = {In calculus, l'Hopital's rule provides a simple way to evaluate the limits of quotient functions when both the numerator and denominator vanish. But what happens when we move beyond real functions on a real interval? In this article, we study when the quotient of two complex-valued functions in higher dimension can be defined continuously at the points where both functions vanish. Surprisingly, the answer is far subtler than in the real-valued setting. We provide a complete characterization for the continuity of the quotient function. We also point out why extending this result to smoother quotients remains an intriguing challenge.}, author = {Chern, Albert and Ishida, Sadashige}, booktitle = {arXiv}, keywords = {l’Hopital theorem, complex functions}, title = {{L'Hopital rules for complex-valued functions in higher dimensions}}, doi = {10.48550/ARXIV.2602.09958}, year = {2026}, } @article{21743, abstract = {We present symplectic structures on the shape space of unparameterized space curves that generalize the classical Marsden–Weinstein structure. Our method integrates the Liouville 1-form of the Marsden–Weinstein structure with Riemannian structures that have been introduced in mathematical shape analysis. We also derive Hamiltonian vector fields for several classical Hamiltonian functions with respect to these new symplectic structures.}, author = {Bauer, Martin and Ishida, Sadashige and Michor, Peter W.}, issn = {1432-1467}, journal = {Journal of Nonlinear Science}, number = {2}, publisher = {Springer Nature}, title = {{Symplectic structures on the space of space curves}}, doi = {10.1007/s00332-026-10266-8}, volume = {36}, year = {2026}, } @article{21744, abstract = {The paraventricular hypothalamus (PVH) controls behavioral and physiologic processes, including appetite, social behavior, autonomic outflow, and pituitary hormone secretion. However, molecular markers for centrally projecting PVH neuron populations remain largely undefined, and a complete census of PVH cell types has not been established. Therefore, we performed extensive single-cell/nucleus RNA sequencing to catalog PVH neuron subtypes and multiplexed error-robust fluorescence in situ hybridization (MERFISH) to map them spatially. Our spatial transcriptomic atlas resolves 26 Sim1+ and 29 GABAergic neuron populations from the PVH and surrounding areas. Additionally, projection-based profiling identified neurons that project to the parabrachial region (PB) and spinal cord, helping to determine PVH populations that regulate satiety and sympathetic nervous system activity, respectively. Notably, activation of PB-projecting PVH neurons expressing Brs3 reduces food intake, and silencing them causes obesity. Together, this atlas contributes high-resolution PVH spatial and circuit-based gene expression profiles, representing a valuable resource for the field of homeostasis.}, author = {Li, Yuxi and Butler, Trevor C. and Nardone, Stefano and Jacobs, Christopher L. and Douglass, Amelia May Barnett and Madara, Joseph C. and McDonough, Miriam C. and Tao, Jenkang and Lowenstein, Elijah D. and Wang, Luhong and Pant, Deepti and Walker, Samuel J. and Wang, Annette and Srinivasan, Harini and Yang, Zongfang and Campbell, John N. and Tsai, Linus T. and Lowell, Bradford B. and Resch, Jon M.}, issn = {2211-1247}, journal = {Cell Reports}, number = {2}, publisher = {Elsevier}, title = {{A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types}}, doi = {10.1016/j.celrep.2025.116904}, volume = {45}, year = {2026}, } @article{21745, abstract = {The small DAHe and DAe spectral classes comprise isolated, hydrogen-dominated atmosphere white dwarfs that exhibit variable photometric flux and Balmer line emission. These mysterious systems offer unique insight into the complex interplay between magnetic fields, stellar rotation and atmospheric activity in single white dwarfs. DAHe stars have detectable magnetic fields through Zeeman-split spectral lines, whereas DAe stars lack such splitting. We report the first discovery and characterization of magnetism in the DAe white dwarf WD J165335.21−100116.33 with new time-resolved spectropolarimetry from FORS2. We detect a weak but variable longitudinal magnetic field with values Bz > −9.2 ± 2.4 kG and Bz < −2.2 ± 1.0 kG. Independent ZTF and ATLAS photometry reveal a consistent period of P = 80.3070 ± 0.0007 h. Time-resolved optical spectroscopy obtained with six ground-based instruments demonstrates strong modulation in the strength of the Hα and Hβ Balmer line emission with P = 80.2922 ± 0.0108 h. The photometric flux and Balmer emission strength vary in antiphase, with the strongest magnetic detections coinciding with phases of low photometric flux and strong line emission. These characteristicssupport the theory that a magnetically active, temperature-inverted spot/region is producing an optically thin chromospheric emission region. Comparison with other DAe and DAHe white dwarfsreveals all systems have a strikingly similar antiphase phenomenology, reinforcing the theory that they are subject to a unified physical mechanism. With the detection of a weak magnetic field, we reclassify WD J165335.21−100116.33 as a low-field DAHe white dwarf. }, author = {Elms, Abbigail K. and Bagnulo, Stefano and Tremblay, Pier Emmanuel and Cunningham, Tim and Munday, James and Landstreet, John and El-Badry, Kareem and Caiazzo, Ilaria and Melis, Carl and Pinter, Viktoria and Weinberger, Alycia}, issn = {1365-2966}, journal = {Monthly Notices of the Royal Astronomical Society}, number = {1}, publisher = {Oxford University Press}, title = {{Detection of a weak magnetic field in the Balmer emission line white dwarf WDJ1653−1001}}, doi = {10.1093/mnras/stag505}, volume = {548}, year = {2026}, } @article{21746, abstract = {As vertebrates transitioned from water to land, locomotion shifted from undulatory swimming to limb-based movement. How spinal circuits and their cell types evolved to support this transition remains unclear. We leverage frog metamorphosis, which recapitulates this transition within a single organism, to define how spinal circuits generate aquatic versus terrestrial motor patterns. At swim stages, spinal architecture is uniform, with a transcriptionally and anatomically homogeneous motor and interneurons. As limbs develop and their movement complexifies, spinal circuits expand in neuron number and subtype diversity. This expansion is most pronounced for V1 inhibitory neurons, which increase ∼70-fold and diversify into transcriptionally distinct subtypes. Disrupting transcription factors defining emerging motor and V1 populations reveals molecular segregation between swim and limb circuits, highlighting the role of subtype diversity in motor coordination. A multifold increase in inhibitory neuron diversity thus underlies the tail-to-limb locomotor transition, providing a framework for spinal circuit adaptation during vertebrate evolution.}, author = {Vijatovic, David and Toma, Florina Alexandra and Ignatyev, Y and Harrington, Zoe P and Sommer, Christoph M and Hauschild, Robert and Smits, Matthijs Geert and Dalla Vecchia, Marco and Trevisan, Alexandra J. and Chapman, Phillip and Julseth, Mara and Brenner-Morton, Susan and Gabitto, Mariano I. and Dasen, Jeremy S. and Bikoff, Jay B. and Sweeney, Lora Beatrice Jaeger}, issn = {2211-1247}, journal = {Cell Reports}, number = {4}, publisher = {Elsevier}, title = {{Multifold increase in spinal inhibitory cell types with emergence of limb movement}}, doi = {10.1016/j.celrep.2026.117227}, volume = {45}, year = {2026}, } @article{21747, abstract = {Entanglement does not always require one particle per party. It was predicted some 30 years ago that a single photon traversing a beam splitter could violate a Bell inequality. Although initially debated, single-photon nonlocality was eventually demonstrated via homodyne measurements. Here, we present an alternate realization that avoids the complexity of homodyne measurements and potential loopholes in their implementation. We violate a Bell inequality by performing joint measurements on two copies of the same single-photon entangled state, where one photon acts as a phase reference for the other, making it self-referential. We observe CHSH parameters of 2.71 = 0.09 and 2.23 = 0.07, depending on the joint measurements implemented. This offers a perspective on single-photon nonlocality and a more accessible experimental route, potentially applicable to general mode-entangled states in diverse platforms.}, author = {Kun, Daniel and Strömberg, Karl T and Dakić, Borivoje and Walther, Philip and Rozema, Lee A.}, issn = {2334-2536}, journal = {Optica}, number = {4}, pages = {745--751}, publisher = {Optica Publishing Group}, title = {{Testing single-photon entanglement using self-referential measurements}}, doi = {10.1364/OPTICA.586172}, volume = {13}, year = {2026}, } @article{21748, abstract = {Cells are defined by lipid membranes that differ in their structure across the tree of life. While the membranes of most bacteria and eukaryotes consist of single-headed bilayer lipids, the membranes of archaea are composed of mixtures of single-headed bilayer lipids and double-headed bolalipids. Archaeal bolalipids can adopt straight or u-shaped conformations, enabling them—together with bilayer lipids—to control whether membranes form bilayer or monolayer structures. Yet, the physical principles governing archaeal membranes remain largely unexplored, especially how membrane structure couples to externally imposed curvature during membrane remodeling. Here, we perform coarse-grained molecular dynamics simulations of toroidal vesicles to systematically probe the effects of all relevant combinations of mean and Gaussian curvatures on shape stability and lipid organization. We find that soft bilayer membranes can sustain all curvatures induced, whereas rigid bolalipid monolayer membranes either transition to different vesicle shapes or rupture. Bilayer-mimicking u-shaped bolalipids and bilayer lipids are spatially accumulated in regions of high mean membrane curvature independent of Gaussian curvature. Our work identifies curvature–composition coupling as a physical signature of archaeal membrane remodeling.}, author = {Frey, Felix F and Santana de Freitas Amaral, Miguel and Šarić, Anđela}, issn = {1089-7690}, journal = {Journal of Chemical Physics}, number = {14}, publisher = {AIP Publishing}, title = {{Cracking donuts and sorting lipids: Geometry controls archaeal membrane stability and lipid organization}}, doi = {10.1063/5.0325170}, volume = {164}, year = {2026}, } @article{21749, abstract = {The collagen triple helix assembles hierarchically into bundled oligomers, solvated networks, and fibers. Synthetic peptide assemblies, driven by supramolecular interactions, can form single triple helices through intrahelical amino acid pairs; however, the principles guiding interhelical associations into higher-order structures remain unclear. Here, we incorporate cation−π and electrostatic charge pairs to probe interhelical interactions and elucidate the mechanisms driving triple helix assembly into fibrils, nanotubes, and nanosheets. Introducing cation−π pairs into a fibrillating collagen mimetic resulted in D-periodic fibrils with pH-sensitive gelation. By alternating the presentation of electrostatic and cation−π pairs, the assembly of another D-periodic fibril featuring inner and outer triple-helical layers was resolved by cryo electron microscopy to a resolution of 8 Å. At physiological pH, antiparallel association of these triple helices leads to the formation of nanotubes. The packing behavior of triple helices correlates with the interhelical interactions, where parallel associations favor fibril formation and antiparallel interactions drive nanotube and nanosheet assembly. These self-assembling triple-helical peptides demonstrate how packing of higher-order structures can be tailored with supramolecular interactions and establish the relationship of different hierarchical collagen-mimetic assemblies as pH-dependent.}, author = {Cole, Carson C. and Kreutzberger, Mark A.B. and Klein, Kevin and Cahue, Kiana A. and Pogostin, Brett H. and Farsheed, Adam C. and Swain, Joseph W.R. and Bui, Thi H. and Dey, Arghadip and Makhoul, Jonathan T. and Dubackic, Marija and Pal, Antara and Olsson, Ulf and Šarić, Anđela and Egelman, Edward H. and Hartgerink, Jeffrey D.}, issn = {1526-4602}, journal = {Biomacromolecules}, number = {4}, pages = {2956--2965}, publisher = {American Chemical Society}, title = {{Supramolecular assembly of collagen-mimetic eptide D-periodic fibrils and nanoassemblies}}, doi = {10.1021/acs.biomac.6c00345}, volume = {27}, year = {2026}, }