[{"volume":15,"file_date_updated":"2024-06-03T12:05:10Z","language":[{"iso":"eng"}],"title":"Phytoalexin sakuranetin attenuates endocytosis and enhances resistance to rice blast","DOAJ_listed":"1","date_created":"2024-06-03T08:54:50Z","abstract":[{"lang":"eng","text":"Phytoalexin sakuranetin functions in resistance against rice blast. However, the mechanisms underlying the effects of sakuranetin remains elusive. Here, we report that rice lines expressing resistance (R) genes were found to contain high levels of sakuranetin, which correlates with attenuated endocytic trafficking of plasma membrane (PM) proteins. Exogenous and endogenous sakuranetin attenuates the endocytosis of various PM proteins and the fungal effector PWL2. Moreover, accumulation of the avirulence protein AvrCO39, resulting from uptake into rice cells by Magnaporthe oryzae, was reduced following treatment with sakuranetin. Pharmacological manipulation of clathrin-mediated endocytic (CME) suggests that this pathway is targeted by sakuranetin. Indeed, attenuation of CME by sakuranetin is sufficient to convey resistance against rice blast. Our data reveals a mechanism of rice against M. oryzae by increasing sakuranetin levels and repressing the CME of pathogen effectors, which is distinct from the action of many R genes that mainly function by modulating transcription."}],"day":"23","isi":1,"scopus_import":"1","pmid":1,"author":[{"full_name":"Jiang, Lihui","first_name":"Lihui","last_name":"Jiang"},{"last_name":"Zhang","full_name":"Zhang, Xiaoyan","first_name":"Xiaoyan"},{"last_name":"Zhao","first_name":"Yiting","full_name":"Zhao, Yiting"},{"last_name":"Zhu","first_name":"Haiyan","full_name":"Zhu, Haiyan"},{"last_name":"Fu","full_name":"Fu, Qijing","first_name":"Qijing"},{"first_name":"Xinqi","full_name":"Lu, Xinqi","last_name":"Lu"},{"last_name":"Huang","full_name":"Huang, Wuying","first_name":"Wuying"},{"first_name":"Xinyue","full_name":"Yang, Xinyue","last_name":"Yang"},{"first_name":"Xuan","full_name":"Zhou, Xuan","last_name":"Zhou"},{"last_name":"Wu","first_name":"Lixia","full_name":"Wu, Lixia"},{"full_name":"Yang, Ao","first_name":"Ao","last_name":"Yang"},{"full_name":"He, Xie","first_name":"Xie","last_name":"He"},{"last_name":"Dong","full_name":"Dong, Man","first_name":"Man"},{"last_name":"Peng","first_name":"Ziai","full_name":"Peng, Ziai"},{"last_name":"Yang","full_name":"Yang, Jing","first_name":"Jing"},{"first_name":"Liwei","full_name":"Guo, Liwei","last_name":"Guo"},{"last_name":"Wen","full_name":"Wen, Jiancheng","first_name":"Jiancheng"},{"last_name":"Huang","first_name":"Huichuan","full_name":"Huang, Huichuan"},{"full_name":"Xie, Yong","first_name":"Yong","last_name":"Xie"},{"first_name":"Shusheng","full_name":"Zhu, Shusheng","last_name":"Zhu"},{"first_name":"Chengyun","full_name":"Li, Chengyun","last_name":"Li"},{"first_name":"Xiahong","full_name":"He, Xiahong","last_name":"He"},{"last_name":"Zhu","full_name":"Zhu, Youyong","first_name":"Youyong"},{"orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jiří","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Du","full_name":"Du, Yunlong","first_name":"Yunlong"}],"quality_controlled":"1","_id":"17103","doi":"10.1038/s41467-024-47746-y","type":"journal_article","publication":"Nature Communications","intvolume":"        15","external_id":{"pmid":["38653755"],"isi":["001207290500013"]},"ddc":["580"],"citation":{"ista":"Jiang L, Zhang X, Zhao Y, Zhu H, Fu Q, Lu X, Huang W, Yang X, Zhou X, Wu L, Yang A, He X, Dong M, Peng Z, Yang J, Guo L, Wen J, Huang H, Xie Y, Zhu S, Li C, He X, Zhu Y, Friml J, Du Y. 2024. Phytoalexin sakuranetin attenuates endocytosis and enhances resistance to rice blast. Nature Communications. 15, 3437.","chicago":"Jiang, Lihui, Xiaoyan Zhang, Yiting Zhao, Haiyan Zhu, Qijing Fu, Xinqi Lu, Wuying Huang, et al. “Phytoalexin Sakuranetin Attenuates Endocytosis and Enhances Resistance to Rice Blast.” <i>Nature Communications</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41467-024-47746-y\">https://doi.org/10.1038/s41467-024-47746-y</a>.","short":"L. Jiang, X. Zhang, Y. Zhao, H. Zhu, Q. Fu, X. Lu, W. Huang, X. Yang, X. Zhou, L. Wu, A. Yang, X. He, M. Dong, Z. Peng, J. Yang, L. Guo, J. Wen, H. Huang, Y. Xie, S. Zhu, C. Li, X. He, Y. Zhu, J. Friml, Y. Du, Nature Communications 15 (2024).","ieee":"L. Jiang <i>et al.</i>, “Phytoalexin sakuranetin attenuates endocytosis and enhances resistance to rice blast,” <i>Nature Communications</i>, vol. 15. Springer Nature, 2024.","mla":"Jiang, Lihui, et al. “Phytoalexin Sakuranetin Attenuates Endocytosis and Enhances Resistance to Rice Blast.” <i>Nature Communications</i>, vol. 15, 3437, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41467-024-47746-y\">10.1038/s41467-024-47746-y</a>.","apa":"Jiang, L., Zhang, X., Zhao, Y., Zhu, H., Fu, Q., Lu, X., … Du, Y. (2024). Phytoalexin sakuranetin attenuates endocytosis and enhances resistance to rice blast. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-024-47746-y\">https://doi.org/10.1038/s41467-024-47746-y</a>","ama":"Jiang L, Zhang X, Zhao Y, et al. Phytoalexin sakuranetin attenuates endocytosis and enhances resistance to rice blast. <i>Nature Communications</i>. 2024;15. doi:<a href=\"https://doi.org/10.1038/s41467-024-47746-y\">10.1038/s41467-024-47746-y</a>"},"acknowledgement":"We thank Professor Jianqiang Wu (Kunming Institute of Botany, Chinese Academy of Sciences) for his generous support with the sakuranetin measurement. We thank International Rice Research Institute (IRRI) for provision of the rice NILs. We thank Professor Zhongkai Zhang (Yunnan Academy of Agricultural Sciences) for his generous support with subcellular structure observation of rice roots. We thank Professor Barbara Valent (Kansas State University) for her generously provision of the plasmid containing the PWL2 gene. We thank Professor Zuhua He (Chinese Academy of Sciences) for the gift of the transgenic rice line expressing the Pigm gene, OsNPR1-RNAi mutant line and ROD1-overexpression rice line. We thank Professor Yinong Yang (The Pennsylvania State University) for provision of the rice line NahG. We thank Professor Muyuan Zhu (Zhejiang University) for provision of the transgenic plants overexpressing miR393a. We thank Professor Zhengge Zhu (Hebei Normal University) for provision of the rice line overexpressing OsPIN3t-GFP. We thank Professor Yanhua Qi (Zhejiang University) for provision of the arf12 mutant line. Thanks also go to Professor Jean-Benoit Morel (Plant Health Institute of Montpellier) for provision of the fungus M. oryzae strain Guy11 (AvrCo39-mRFP). This work was supported by grants from the National Natural Science Foundation of China (Grant Nos. 32260085, 31460453, 31660501, 31860064, 31760500 and 31901870), the Major Special Program for Scientific Research, Education Department of Yunnan Province (Grant No. ZD2015005). The project was also sponsored by SRF for ROCS, SEM (Grant No. [2013] 1792), the Key Projects of Applied Basic Research Plan of Yunnan Province (Grant No. 2017FA018, 202301AS070082), the Major Science and Technology Project in Yunnan Province (202102AE090042, 202202AE090036 and 202102AE090017), the Young and Middle-Aged Academic and Technical Leaders Reserve Talent Program in Yunnan Province (202205AC160076), the China Postdoctoral Science Foundation (2019M653849XB) and the National Key Research and Development Program of China (2023YFE0107500).","oa":1,"department":[{"_id":"JiFr"}],"article_number":"3437","article_processing_charge":"Yes","date_updated":"2025-09-08T07:46:24Z","publication_status":"published","article_type":"original","month":"04","date_published":"2024-04-23T00:00:00Z","publisher":"Springer Nature","year":"2024","status":"public","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"eissn":["2041-1723"]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"file_id":"17110","relation":"main_file","date_created":"2024-06-03T12:05:10Z","file_name":"2024_NatureComm_Jiang.pdf","date_updated":"2024-06-03T12:05:10Z","success":1,"file_size":8013695,"checksum":"80cb2f2c538e81064f4836b54bc313ca","content_type":"application/pdf","access_level":"open_access","creator":"dernst"}]},{"issue":"4","status":"public","year":"2024","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"issn":["2542-4653"]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"date_updated":"2024-06-03T11:18:51Z","success":1,"creator":"dernst","content_type":"application/pdf","file_size":4973291,"access_level":"open_access","checksum":"6fdeecd21c166db8dedb927ecc2e6025","file_id":"17109","relation":"main_file","file_name":"2024_SciPostPhys_Kraemer.pdf","date_created":"2024-06-03T11:18:51Z"}],"oa":1,"article_number":"097","department":[{"_id":"EdHa"}],"article_processing_charge":"No","publication_status":"published","date_updated":"2025-09-08T07:45:40Z","date_published":"2024-04-08T00:00:00Z","article_type":"original","month":"04","publisher":"SciPost Foundation","author":[{"last_name":"Krämer","full_name":"Krämer, Johannes C.","first_name":"Johannes C."},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","full_name":"Hannezo, Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561"},{"first_name":"Gerhard","full_name":"Gompper, Gerhard","last_name":"Gompper"},{"last_name":"Elgeti","first_name":"Jens","full_name":"Elgeti, Jens"}],"quality_controlled":"1","_id":"17104","doi":"10.21468/scipostphys.16.4.097","publication":"SciPost Physics","type":"journal_article","intvolume":"        16","arxiv":1,"external_id":{"isi":["001202370200001"],"arxiv":["2310.04272"]},"ddc":["530"],"citation":{"apa":"Krämer, J. C., Hannezo, E. B., Gompper, G., &#38; Elgeti, J. (2024). Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells. <i>SciPost Physics</i>. SciPost Foundation. <a href=\"https://doi.org/10.21468/scipostphys.16.4.097\">https://doi.org/10.21468/scipostphys.16.4.097</a>","ama":"Krämer JC, Hannezo EB, Gompper G, Elgeti J. Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells. <i>SciPost Physics</i>. 2024;16(4). doi:<a href=\"https://doi.org/10.21468/scipostphys.16.4.097\">10.21468/scipostphys.16.4.097</a>","mla":"Krämer, Johannes C., et al. “Mechanically-Driven Stem Cell Separation in Tissues Caused by Proliferating Daughter Cells.” <i>SciPost Physics</i>, vol. 16, no. 4, 097, SciPost Foundation, 2024, doi:<a href=\"https://doi.org/10.21468/scipostphys.16.4.097\">10.21468/scipostphys.16.4.097</a>.","ieee":"J. C. Krämer, E. B. Hannezo, G. Gompper, and J. Elgeti, “Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells,” <i>SciPost Physics</i>, vol. 16, no. 4. SciPost Foundation, 2024.","chicago":"Krämer, Johannes C., Edouard B Hannezo, Gerhard Gompper, and Jens Elgeti. “Mechanically-Driven Stem Cell Separation in Tissues Caused by Proliferating Daughter Cells.” <i>SciPost Physics</i>. SciPost Foundation, 2024. <a href=\"https://doi.org/10.21468/scipostphys.16.4.097\">https://doi.org/10.21468/scipostphys.16.4.097</a>.","short":"J.C. Krämer, E.B. Hannezo, G. Gompper, J. Elgeti, SciPost Physics 16 (2024).","ista":"Krämer JC, Hannezo EB, Gompper G, Elgeti J. 2024. Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells. SciPost Physics. 16(4), 097."},"acknowledgement":"JE and JK gratefully acknowledge financial support from the Initiative and Networking Fund (IVF) via the grant number ERC-RA-004. Simulations were performed with computing resources granted by RWTH Aachen University under project ‘rwth0475’.","volume":16,"file_date_updated":"2024-06-03T11:18:51Z","language":[{"iso":"eng"}],"title":"Mechanically-driven stem cell separation in tissues caused by proliferating daughter cells","date_created":"2024-06-03T08:58:44Z","day":"08","abstract":[{"text":"The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth, the regulatory mechanisms, both cell-intrinsic and collective, which ensure tissue steady-state are still poorly understood. Here, we develop a computational model that incorporates basic assumptions of stem cell renewal into distinct populations and mechanical interactions between cells. We find that the model generates unexpected dynamic features: stem cells repel each other in the bulk tissue and are thus found rather isolated, as in a number of in vivo contexts. By mapping the system onto a gas of passive Brownian particles with effective repulsive interactions, that arise from the generated flows of differentiated cells, we show that we can quantitatively describe such stem cell distribution in tissues. The interaction potential between a pair of stem cells decays exponentially with a characteristic length that spans several cell sizes, corresponding to the volume of cells generated per stem cell division. Our findings may help understanding the dynamics of normal and cancerous epithelial tissues.","lang":"eng"}],"isi":1,"scopus_import":"1"},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"file_id":"17107","relation":"main_file","date_created":"2024-06-03T10:33:17Z","file_name":"2024_AngChemieInt_Sheng.pdf","date_updated":"2024-06-03T10:33:17Z","success":1,"checksum":"7ecb0892051f6ed8f6a6f25baa47543a","content_type":"application/pdf","access_level":"open_access","file_size":2363206,"creator":"dernst"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"has_accepted_license":"1","issue":"23","year":"2024","status":"public","publisher":"Wiley","date_updated":"2025-04-23T07:48:28Z","publication_status":"published","article_type":"original","month":"03","date_published":"2024-03-26T00:00:00Z","department":[{"_id":"RaKl"}],"article_number":"e202404878","article_processing_charge":"Yes (in subscription journal)","oa":1,"intvolume":"        63","external_id":{"pmid":["38530132"]},"ddc":["540"],"citation":{"short":"J. Sheng, J. Perego, S. Bracco, P. Cieciórski, W. Danowski, A. Comotti, B.L. Feringa, Angewandte Chemie International Edition 63 (2024).","chicago":"Sheng, Jinyu, Jacopo Perego, Silvia Bracco, Piotr Cieciórski, Wojciech Danowski, Angiolina Comotti, and Ben L. Feringa. “Orthogonal Photoswitching in a Porous Organic Framework.” <i>Angewandte Chemie International Edition</i>. Wiley, 2024. <a href=\"https://doi.org/10.1002/anie.202404878\">https://doi.org/10.1002/anie.202404878</a>.","ista":"Sheng J, Perego J, Bracco S, Cieciórski P, Danowski W, Comotti A, Feringa BL. 2024. Orthogonal photoswitching in a porous organic framework. Angewandte Chemie International Edition. 63(23), e202404878.","ama":"Sheng J, Perego J, Bracco S, et al. Orthogonal photoswitching in a porous organic framework. <i>Angewandte Chemie International Edition</i>. 2024;63(23). doi:<a href=\"https://doi.org/10.1002/anie.202404878\">10.1002/anie.202404878</a>","apa":"Sheng, J., Perego, J., Bracco, S., Cieciórski, P., Danowski, W., Comotti, A., &#38; Feringa, B. L. (2024). Orthogonal photoswitching in a porous organic framework. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202404878\">https://doi.org/10.1002/anie.202404878</a>","mla":"Sheng, Jinyu, et al. “Orthogonal Photoswitching in a Porous Organic Framework.” <i>Angewandte Chemie International Edition</i>, vol. 63, no. 23, e202404878, Wiley, 2024, doi:<a href=\"https://doi.org/10.1002/anie.202404878\">10.1002/anie.202404878</a>.","ieee":"J. Sheng <i>et al.</i>, “Orthogonal photoswitching in a porous organic framework,” <i>Angewandte Chemie International Edition</i>, vol. 63, no. 23. Wiley, 2024."},"acknowledgement":"This work was supported from the following sources: China Scholarship Council (CSC PhD Fellowship No. 201808330459 to J.S.), the Ministry of Education, Culture and Science of the Netherlands (Gravitation Program No. 024.001.035 to BLF), Financial support from The Netherlands Organization for Scientific Research (NWO-CW), the European Research Council (ERC; advanced Grant No. 694345 to B.L.F.). PRIN (SHERPA 2020 No. H45F21003430001) and PRIN (HySTAR 2022 No. H53D23004720006) and Lombardy Region for “Enhancing Photosynthesis” grant (2021-2023 No. H45F21002830007). W.D. is grateful for financial support from Marie Skłodowska-Curie Actions (Individual Fellowship No. 101027639). P.C. is grateful for the financial support provided by the PRELUDIUM grant from the National Science Center Poland (Reg. No: 2023/49/N/ST5/01864).","type":"journal_article","publication":"Angewandte Chemie International Edition","_id":"17105","doi":"10.1002/anie.202404878","author":[{"full_name":"Sheng, Jinyu","first_name":"Jinyu","id":"639f0526-27c9-11ee-95a6-966cd7f102d8","last_name":"Sheng"},{"last_name":"Perego","first_name":"Jacopo","full_name":"Perego, Jacopo"},{"last_name":"Bracco","full_name":"Bracco, Silvia","first_name":"Silvia"},{"last_name":"Cieciórski","full_name":"Cieciórski, Piotr","first_name":"Piotr"},{"full_name":"Danowski, Wojciech","first_name":"Wojciech","last_name":"Danowski"},{"last_name":"Comotti","first_name":"Angiolina","full_name":"Comotti, Angiolina"},{"last_name":"Feringa","full_name":"Feringa, Ben L.","first_name":"Ben L."}],"quality_controlled":"1","pmid":1,"scopus_import":"1","date_created":"2024-06-03T09:00:01Z","day":"26","abstract":[{"lang":"eng","text":"The development of photoresponsive systems with non-invasive orthogonal control by distinct wavelengths of light is still in its infancy. In particular, the design of photochemically triggered-orthogonal systems integrated into solid materials that enable multiple dynamic control over their properties remains a longstanding challenge. Here, we report the orthogonal and reversible control of two types of photoswitches in an integrated solid porous framework, that is, visible-light responsive o-fluoroazobenzene and nitro-spiropyran motifs. The properties of the constructed material can be selectively controlled by different wavelengths of light thus generating four distinct states providing a basis for dynamic multifunctional materials. Solid-state NMR spectroscopy demonstrated the selective transformation of the azobenzene switch in the bulk, which in turn modulates N2 and CO2 adsorption."}],"volume":63,"file_date_updated":"2024-06-03T10:33:17Z","language":[{"iso":"eng"}],"title":"Orthogonal photoswitching in a porous organic framework"},{"_id":"17122","doi":"10.1186/s12888-024-05849-2","author":[{"last_name":"Ramming","full_name":"Ramming, Hannah","first_name":"Hannah"},{"last_name":"Theuerkauf","full_name":"Theuerkauf, Linda","first_name":"Linda"},{"last_name":"Hoos","full_name":"Hoos, Olaf","first_name":"Olaf"},{"full_name":"Lichter, Katharina","first_name":"Katharina","id":"39302e62-fcfc-11ec-8196-8b01447dbd3d","orcid":"0000-0002-1485-0351","last_name":"Lichter"},{"last_name":"Kittel-Schneider","full_name":"Kittel-Schneider, Sarah","first_name":"Sarah"}],"quality_controlled":"1","intvolume":"        24","external_id":{"pmid":["38811916"]},"ddc":["570"],"citation":{"chicago":"Ramming, Hannah, Linda Theuerkauf, Olaf Hoos, Katharina Lichter, and Sarah Kittel-Schneider. “The Association between Maximal Muscle Strength, Disease Severity and Psychopharmacotherapy among Young to Middle-Aged Inpatients with Affective Disorders – a Prospective Pilot Study.” <i>BMC Psychiatry</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1186/s12888-024-05849-2\">https://doi.org/10.1186/s12888-024-05849-2</a>.","short":"H. Ramming, L. Theuerkauf, O. Hoos, K. Lichter, S. Kittel-Schneider, BMC Psychiatry 24 (2024).","ista":"Ramming H, Theuerkauf L, Hoos O, Lichter K, Kittel-Schneider S. 2024. The association between maximal muscle strength, disease severity and psychopharmacotherapy among young to middle-aged inpatients with affective disorders – a prospective pilot study. BMC Psychiatry. 24, 401.","apa":"Ramming, H., Theuerkauf, L., Hoos, O., Lichter, K., &#38; Kittel-Schneider, S. (2024). The association between maximal muscle strength, disease severity and psychopharmacotherapy among young to middle-aged inpatients with affective disorders – a prospective pilot study. <i>BMC Psychiatry</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s12888-024-05849-2\">https://doi.org/10.1186/s12888-024-05849-2</a>","ama":"Ramming H, Theuerkauf L, Hoos O, Lichter K, Kittel-Schneider S. The association between maximal muscle strength, disease severity and psychopharmacotherapy among young to middle-aged inpatients with affective disorders – a prospective pilot study. <i>BMC Psychiatry</i>. 2024;24. doi:<a href=\"https://doi.org/10.1186/s12888-024-05849-2\">10.1186/s12888-024-05849-2</a>","ieee":"H. Ramming, L. Theuerkauf, O. Hoos, K. Lichter, and S. Kittel-Schneider, “The association between maximal muscle strength, disease severity and psychopharmacotherapy among young to middle-aged inpatients with affective disorders – a prospective pilot study,” <i>BMC Psychiatry</i>, vol. 24. Springer Nature, 2024.","mla":"Ramming, Hannah, et al. “The Association between Maximal Muscle Strength, Disease Severity and Psychopharmacotherapy among Young to Middle-Aged Inpatients with Affective Disorders – a Prospective Pilot Study.” <i>BMC Psychiatry</i>, vol. 24, 401, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1186/s12888-024-05849-2\">10.1186/s12888-024-05849-2</a>."},"acknowledgement":"This work was supported by the project ‘Fellows Ride’ of the Thomas Lurz und Dieter Schneider Stiftung and by the ‘Würzburger Bündnis gegen Depression’ (to S.K.-S).\r\nOpen Access funding enabled and organized by Projekt DEAL.","publication":"BMC Psychiatry","type":"journal_article","date_created":"2024-06-09T22:01:01Z","abstract":[{"lang":"eng","text":"Background: Motor alterations and lowered physical activity are common in affective disorders. Previous research has indicated a link between depressive symptoms and declining muscle strength primarily focusing on the elderly but not younger individuals. Thus, we aimed to evaluate the relationship between mood and muscle strength in a sample of N = 73 young to middle-aged hospitalized patients (18–49 years, mean age 30.7 years) diagnosed with major depressive, bipolar and schizoaffective disorder, with a focus on moderating effects of psychopharmacotherapy. The study was carried out as a prospective observational study at a German psychiatric university hospital between September 2021 and March 2022.\r\nMethods: Employing a standardized strength circuit consisting of computerized strength training devices, we measured the maximal muscle strength (Fmax) using three repetitions maximum across four muscle regions (abdomen, arm, back, leg) at three time points (t1-t3) over four weeks accompanied by psychometric testing (MADRS, BPRS, YRMS) and blood lipid profiling in a clinical setting. For analysis of psychopharmacotherapy, medication was split into activating (AM) and inhibiting (IM) medication and dosages were normalized by the respective WHO defined daily dose.\r\nResults: While we observed a significant decrease of the MADRS score and increase of the relative total Fmax (rTFmax) in the first two weeks (t1-t2) but not later (both p < .001), we did not reveal a significant bivariate correlation between disease severity (MADRS) and muscle strength (rTFmax) at any of the timepoints. Individuals with longer disease history displayed reduced rTFmax (p = .048). IM was significantly associated with decreased rTFmax (p = .032). Regression models provide a more substantial effect of gender, age, and IM on muscle strength than the depressive episode itself (p < .001).\r\nConclusions: The results of the study indicate that disease severity and muscle strength are not associated in young to middle-aged inpatients with affective disorders using a strength circuit as observational measurement. Future research will be needed to differentiate the effect of medication, gender, and age on muscle strength and to develop interventions for prevention of muscle weakness, especially in younger patients with chronic affective illnesses."}],"day":"29","volume":24,"file_date_updated":"2024-06-10T10:44:26Z","language":[{"iso":"eng"}],"title":"The association between maximal muscle strength, disease severity and psychopharmacotherapy among young to middle-aged inpatients with affective disorders – a prospective pilot study","pmid":1,"scopus_import":"1","has_accepted_license":"1","status":"public","year":"2024","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"creator":"dernst","access_level":"open_access","file_size":2320147,"checksum":"5df60d3c9388955c5b682ea34748d59d","content_type":"application/pdf","success":1,"date_updated":"2024-06-10T10:44:26Z","file_name":"2024_BMCPsychiatry_Ramming.pdf","date_created":"2024-06-10T10:44:26Z","relation":"main_file","file_id":"17131"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1471-244X"]},"department":[{"_id":"PeJo"}],"article_number":"401","article_processing_charge":"Yes (via OA deal)","oa":1,"publisher":"Springer Nature","date_updated":"2025-04-23T07:51:51Z","publication_status":"published","date_published":"2024-05-29T00:00:00Z","article_type":"original","month":"05"},{"scopus_import":"1","isi":1,"pmid":1,"related_material":{"link":[{"url":"https://github.com/dbrueckner/SelforgInformation","relation":"software"},{"description":"News on the ISTA website","url":"https://ista.ac.at/en/news/the-embryo-assembles-itself/","relation":"press_release"}]},"language":[{"iso":"eng"}],"title":"Information content and optimization of self-organized developmental systems","volume":121,"file_date_updated":"2024-06-10T10:27:37Z","date_created":"2024-06-09T22:01:02Z","day":"04","abstract":[{"text":"A key feature of many developmental systems is their ability to self-organize spatial patterns of functionally distinct cell fates. To ensure proper biological function, such patterns must be established reproducibly, by controlling and even harnessing intrinsic and extrinsic fluctuations. While the relevant molecular processes are increasingly well understood, we lack a principled framework to quantify the performance of such stochastic self-organizing systems. To that end, we introduce an information-theoretic measure for self-organized fate specification during embryonic development. We show that the proposed measure assesses the total information content of fate patterns and decomposes it into interpretable contributions corresponding to the positional and correlational information. By optimizing the proposed measure, our framework provides a normative theory for developmental circuits, which we demonstrate on lateral inhibition, cell type proportioning, and reaction–diffusion models of self-organization. This paves a way toward a classification of developmental systems based on a common information-theoretic language, thereby organizing the zoo of implicated chemical and mechanical signaling processes.","lang":"eng"}],"type":"journal_article","publication":"Proceedings of the National Academy of Sciences of the United States of America","ddc":["570"],"external_id":{"isi":["001244835000006"],"pmid":["38819997"]},"acknowledgement":"We thank Wiktor Młynarski, Juraj Majek, Michal Hledík, Fridtjof Brauns, Nikolas Claussen, Benjamin Zoller, Erwin Frey, Thomas Gregor, and Edouard Hannezo for inspiring discussions. D.B.B. was supported by the NOMIS foundation as a NOMIS Fellow and by an European Molecular Biology Organization (EMBO) Postdoctoral Fellowship (ALTF 343-2022). This research was performed in part at the Aspen Center for Physics, which is supported by NSF Grant No. PHY-1607611, and Kavli Institute for Theoretical Physics (KITP) Santa Barbara, supported by NSF Grant No. PHY-1748958 and the Gordon and Betty Moore Foundation Grant No. 2919.02.","citation":{"ama":"Brückner D, Tkačik G. Information content and optimization of self-organized developmental systems. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(23). doi:<a href=\"https://doi.org/10.1073/pnas.2322326121\">10.1073/pnas.2322326121</a>","apa":"Brückner, D., &#38; Tkačik, G. (2024). Information content and optimization of self-organized developmental systems. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2322326121\">https://doi.org/10.1073/pnas.2322326121</a>","ieee":"D. Brückner and G. Tkačik, “Information content and optimization of self-organized developmental systems,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 23. National Academy of Sciences, 2024.","mla":"Brückner, David, and Gašper Tkačik. “Information Content and Optimization of Self-Organized Developmental Systems.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 23, e2322326121, National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2322326121\">10.1073/pnas.2322326121</a>.","short":"D. Brückner, G. Tkačik, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","chicago":"Brückner, David, and Gašper Tkačik. “Information Content and Optimization of Self-Organized Developmental Systems.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2322326121\">https://doi.org/10.1073/pnas.2322326121</a>.","ista":"Brückner D, Tkačik G. 2024. Information content and optimization of self-organized developmental systems. Proceedings of the National Academy of Sciences of the United States of America. 121(23), e2322326121."},"intvolume":"       121","quality_controlled":"1","author":[{"full_name":"Brückner, David","first_name":"David","id":"e1e86031-6537-11eb-953a-f7ab92be508d","orcid":"0000-0001-7205-2975","last_name":"Brückner"},{"orcid":"0000-0002-6699-1455","last_name":"Tkačik","first_name":"Gašper","full_name":"Tkačik, Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87"}],"_id":"17123","doi":"10.1073/pnas.2322326121","project":[{"grant_number":"ALTF 343-2022","name":"A mechano-chemical theory for stem cell fate decisions in organoid development","_id":"34e2a5b5-11ca-11ed-8bc3-b2265616ef0b"}],"date_updated":"2025-09-08T07:51:01Z","APC_amount":"2570,79 EUR","publication_status":"published","date_published":"2024-06-04T00:00:00Z","month":"06","article_type":"original","publisher":"National Academy of Sciences","oa":1,"article_processing_charge":"Yes (in subscription journal)","department":[{"_id":"EdHa"},{"_id":"GaTk"}],"article_number":"e2322326121","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"OA_place":"publisher","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Published Version","file":[{"file_id":"17130","date_created":"2024-06-10T10:27:37Z","file_name":"2024_PNAS_Brueckner.pdf","relation":"main_file","date_updated":"2024-06-10T10:27:37Z","checksum":"59797a75db7beb3721ed7a4d14c241f9","file_size":12329234,"access_level":"open_access","content_type":"application/pdf","creator":"dernst","success":1}],"OA_type":"hybrid","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"status":"public","year":"2024","issue":"23","has_accepted_license":"1","corr_author":"1"},{"publication":"Journal of Visualized Experiments","type":"journal_article","external_id":{"pmid":["38829127"],"isi":["001281657200005"]},"ddc":["530"],"acknowledgement":"The Scientific Service Units (SSU) of ISTA supported this research through resources provided by the Electron Microscopy Facility (EMF) and the Lab Support Facility (LSF). This work was financially supported by the Institute of Science and Technology Austria and the Werner Siemens Foundation.","citation":{"ista":"Fiedler C, Liu Y, Ibáñez M. 2024. Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. Journal of Visualized Experiments. 2024(207), e66278.","chicago":"Fiedler, Christine, Yu Liu, and Maria Ibáñez. “Solution-Processed, Surface-Engineered, Polycrystalline CdSe-SnSe Exhibiting Low Thermal Conductivity.” <i>Journal of Visualized Experiments</i>. MyJove Corporation, 2024. <a href=\"https://doi.org/10.3791/66278\">https://doi.org/10.3791/66278</a>.","short":"C. Fiedler, Y. Liu, M. Ibáñez, Journal of Visualized Experiments 2024 (2024).","mla":"Fiedler, Christine, et al. “Solution-Processed, Surface-Engineered, Polycrystalline CdSe-SnSe Exhibiting Low Thermal Conductivity.” <i>Journal of Visualized Experiments</i>, vol. 2024, no. 207, e66278, MyJove Corporation, 2024, doi:<a href=\"https://doi.org/10.3791/66278\">10.3791/66278</a>.","ieee":"C. Fiedler, Y. Liu, and M. Ibáñez, “Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity,” <i>Journal of Visualized Experiments</i>, vol. 2024, no. 207. MyJove Corporation, 2024.","apa":"Fiedler, C., Liu, Y., &#38; Ibáñez, M. (2024). Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. <i>Journal of Visualized Experiments</i>. MyJove Corporation. <a href=\"https://doi.org/10.3791/66278\">https://doi.org/10.3791/66278</a>","ama":"Fiedler C, Liu Y, Ibáñez M. Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity. <i>Journal of Visualized Experiments</i>. 2024;2024(207). doi:<a href=\"https://doi.org/10.3791/66278\">10.3791/66278</a>"},"intvolume":"      2024","quality_controlled":"1","author":[{"last_name":"Fiedler","full_name":"Fiedler, Christine","first_name":"Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366"},{"orcid":"0000-0001-7313-6740","last_name":"Liu","full_name":"Liu, Yu","first_name":"Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","full_name":"Ibáñez, Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843"}],"_id":"17124","doi":"10.3791/66278","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"scopus_import":"1","isi":1,"pmid":1,"language":[{"iso":"eng"}],"title":"Solution-processed, surface-engineered, polycrystalline CdSe-SnSe exhibiting low thermal conductivity","license":"https://creativecommons.org/licenses/by-nc-nd/3.0/","volume":2024,"file_date_updated":"2025-02-17T15:08:55Z","date_created":"2024-06-09T22:01:02Z","day":"01","abstract":[{"text":"In recent years, solution processes have gained considerable traction as a cost-effective and scalable method to produce high-performance thermoelectric materials. The process entails a series of critical steps: synthesis, purification, thermal treatments, and consolidation, each playing a pivotal role in determining performance, stability, and reproducibility. We have noticed a need for more comprehensive details for each of the described steps in most published works. Recognizing the significance of detailed synthetic protocols, we describe here the approach used to synthesize and characterize one of the highest-performing polycrystalline p-type SnSe. In particular, we report the synthesis of SnSe particles in water and the subsequent surface treatment with CdSe molecular complexes that yields CdSe-SnSe nanocomposites upon consolidation. Moreover, the surface treatment inhibits grain growth through Zenner pinning of secondary phase CdSe nanoparticles and enhances defect formation at different length scales. The enhanced complexity in the CdSe-SnSe nanocomposite microstructure with respect to SnSe promotes phonon scattering and thereby significantly reduces the thermal conductivity. Such surface engineering provides opportunities in solution processing for introducing and controlling defects, making it possible to optimize the transport properties and attain a high thermoelectric figure of merit.","lang":"eng"}],"publication_identifier":{"issn":["1940-087X"]},"OA_place":"publisher","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Published Version","file":[{"success":1,"file_size":1371995,"content_type":"application/pdf","access_level":"open_access","checksum":"ddb41f1ce2333484ab5cd109ac2941c0","creator":"dernst","date_updated":"2025-02-17T15:08:55Z","relation":"main_file","date_created":"2025-02-17T15:08:55Z","file_name":"2024_JoVE_Fiedler.pdf","file_id":"19047"}],"OA_type":"hybrid","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/3.0/legalcode"},"status":"public","issue":"207","year":"2024","corr_author":"1","has_accepted_license":"1","APC_amount":"4394,84 EUR","date_updated":"2025-09-08T07:51:46Z","publication_status":"published","month":"05","article_type":"original","date_published":"2024-05-01T00:00:00Z","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"}],"publisher":"MyJove Corporation","oa":1,"article_processing_charge":"Yes (in subscription journal)","article_number":"e66278","department":[{"_id":"MaIb"}]},{"pmid":1,"scopus_import":"1","isi":1,"day":"30","abstract":[{"text":"We explore the potential of nanocrystals (a term used equivalently to nanoparticles) as building blocks for nanomaterials, and the current advances and open challenges for fundamental science developments and applications. Nanocrystal assemblies are inherently multiscale, and the generation of revolutionary material properties requires a precise understanding of the relationship between structure and function, the former being determined by classical effects and the latter often by quantum effects. With an emphasis on theory and computation, we discuss challenges that hamper current assembly strategies and to what extent nanocrystal assemblies represent thermodynamic equilibrium or kinetically trapped metastable states. We also examine dynamic effects and optimization of assembly protocols. Finally, we discuss promising material functions and examples of their realization with nanocrystal assemblies.","lang":"eng"}],"date_created":"2024-06-09T22:01:02Z","title":"Nanocrystal assemblies: Current advances and open problems","language":[{"iso":"eng"}],"volume":18,"citation":{"ieee":"C. L. Bassani <i>et al.</i>, “Nanocrystal assemblies: Current advances and open problems,” <i>ACS Nano</i>, vol. 18, no. 23. American Chemical Society, pp. 14791–14840, 2024.","mla":"Bassani, Carlos L., et al. “Nanocrystal Assemblies: Current Advances and Open Problems.” <i>ACS Nano</i>, vol. 18, no. 23, American Chemical Society, 2024, pp. 14791–840, doi:<a href=\"https://doi.org/10.1021/acsnano.3c10201\">10.1021/acsnano.3c10201</a>.","ama":"Bassani CL, Van Anders G, Banin U, et al. Nanocrystal assemblies: Current advances and open problems. <i>ACS Nano</i>. 2024;18(23):14791-14840. doi:<a href=\"https://doi.org/10.1021/acsnano.3c10201\">10.1021/acsnano.3c10201</a>","apa":"Bassani, C. L., Van Anders, G., Banin, U., Baranov, D., Chen, Q., Dijkstra, M., … Travesset, A. (2024). Nanocrystal assemblies: Current advances and open problems. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.3c10201\">https://doi.org/10.1021/acsnano.3c10201</a>","ista":"Bassani CL, Van Anders G, Banin U, Baranov D, Chen Q, Dijkstra M, Dimitriyev MS, Efrati E, Faraudo J, Gang O, Gaston N, Golestanian R, Guerrero-Garcia GI, Gruenwald M, Haji-Akbari A, Ibáñez M, Karg M, Kraus T, Lee B, Van Lehn RC, Macfarlane RJ, Mognetti BM, Nikoubashman A, Osat S, Prezhdo OV, Rotskoff GM, Saiz L, Shi AC, Skrabalak S, Smalyukh II, Tagliazucchi M, Talapin DV, Tkachenko AV, Tretiak S, Vaknin D, Widmer-Cooper A, Wong GCL, Ye X, Zhou S, Rabani E, Engel M, Travesset A. 2024. Nanocrystal assemblies: Current advances and open problems. ACS Nano. 18(23), 14791–14840.","short":"C.L. Bassani, G. Van Anders, U. Banin, D. Baranov, Q. Chen, M. Dijkstra, M.S. Dimitriyev, E. Efrati, J. Faraudo, O. Gang, N. Gaston, R. Golestanian, G.I. Guerrero-Garcia, M. Gruenwald, A. Haji-Akbari, M. Ibáñez, M. Karg, T. Kraus, B. Lee, R.C. Van Lehn, R.J. Macfarlane, B.M. Mognetti, A. Nikoubashman, S. Osat, O.V. Prezhdo, G.M. Rotskoff, L. Saiz, A.C. Shi, S. Skrabalak, I.I. Smalyukh, M. Tagliazucchi, D.V. Talapin, A.V. Tkachenko, S. Tretiak, D. Vaknin, A. Widmer-Cooper, G.C.L. Wong, X. Ye, S. Zhou, E. Rabani, M. Engel, A. Travesset, ACS Nano 18 (2024) 14791–14840.","chicago":"Bassani, Carlos L., Greg Van Anders, Uri Banin, Dmitry Baranov, Qian Chen, Marjolein Dijkstra, Michael S. Dimitriyev, et al. “Nanocrystal Assemblies: Current Advances and Open Problems.” <i>ACS Nano</i>. American Chemical Society, 2024. <a href=\"https://doi.org/10.1021/acsnano.3c10201\">https://doi.org/10.1021/acsnano.3c10201</a>."},"acknowledgement":"This research was supported in part by the National Science Foundation under Grant No. NSF PHY-1748958 to the Kavli Institute for Theoretical Physics. The biophysics part of this paper was supported in part by the Gordon and Betty Moore Foundation Grant No. 2919.02. CLB acknowledges the sponsorship of the Alexander von Humboldt Foundation through the Humboldt Research Fellowship for postdoctoral researchers, and the support of the Emerging Talents Initiative (ETI) and the EAM Starting Grant (EAM-SG23-1) of the Competence Center Engineering of Advanced Materials of the Friedrich-Alexander-Universität Erlangen-Nürnberg. CLB and ME acknowledge the support of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Project-ID 416229255-SFB 1411. The research of AT was supported by the U.S. Department of Energy (U.S. DOE), Office of Basic Energy Sciences, Division of Materials Sciences and Engineering. Iowa State University operates Ames National Laboratory for the U.S. DOE under Contract DE-AC02-07CH11358.","external_id":{"pmid":["38814908"],"isi":["001236199900001"]},"intvolume":"        18","type":"journal_article","publication":"ACS Nano","doi":"10.1021/acsnano.3c10201","_id":"17125","quality_controlled":"1","page":"14791-14840","author":[{"last_name":"Bassani","full_name":"Bassani, Carlos L.","first_name":"Carlos L."},{"first_name":"Greg","full_name":"Van Anders, Greg","last_name":"Van Anders"},{"last_name":"Banin","first_name":"Uri","full_name":"Banin, Uri"},{"first_name":"Dmitry","full_name":"Baranov, Dmitry","last_name":"Baranov"},{"full_name":"Chen, Qian","first_name":"Qian","last_name":"Chen"},{"last_name":"Dijkstra","full_name":"Dijkstra, Marjolein","first_name":"Marjolein"},{"full_name":"Dimitriyev, Michael S.","first_name":"Michael S.","last_name":"Dimitriyev"},{"last_name":"Efrati","full_name":"Efrati, Efi","first_name":"Efi"},{"first_name":"Jordi","full_name":"Faraudo, Jordi","last_name":"Faraudo"},{"first_name":"Oleg","full_name":"Gang, Oleg","last_name":"Gang"},{"first_name":"Nicola","full_name":"Gaston, Nicola","last_name":"Gaston"},{"first_name":"Ramin","full_name":"Golestanian, Ramin","last_name":"Golestanian"},{"last_name":"Guerrero-Garcia","full_name":"Guerrero-Garcia, G. Ivan","first_name":"G. Ivan"},{"first_name":"Michael","full_name":"Gruenwald, Michael","last_name":"Gruenwald"},{"last_name":"Haji-Akbari","first_name":"Amir","full_name":"Haji-Akbari, Amir"},{"orcid":"0000-0001-5013-2843","last_name":"Ibáñez","first_name":"Maria","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Matthias","full_name":"Karg, Matthias","last_name":"Karg"},{"last_name":"Kraus","full_name":"Kraus, Tobias","first_name":"Tobias"},{"first_name":"Byeongdu","full_name":"Lee, Byeongdu","last_name":"Lee"},{"last_name":"Van Lehn","first_name":"Reid C.","full_name":"Van Lehn, Reid C."},{"first_name":"Robert J.","full_name":"Macfarlane, Robert J.","last_name":"Macfarlane"},{"last_name":"Mognetti","first_name":"Bortolo M.","full_name":"Mognetti, Bortolo M."},{"last_name":"Nikoubashman","full_name":"Nikoubashman, Arash","first_name":"Arash"},{"full_name":"Osat, Saeed","first_name":"Saeed","last_name":"Osat"},{"last_name":"Prezhdo","first_name":"Oleg V.","full_name":"Prezhdo, Oleg V."},{"first_name":"Grant M.","full_name":"Rotskoff, Grant M.","last_name":"Rotskoff"},{"first_name":"Leonor","full_name":"Saiz, Leonor","last_name":"Saiz"},{"last_name":"Shi","first_name":"An Chang","full_name":"Shi, An Chang"},{"last_name":"Skrabalak","first_name":"Sara","full_name":"Skrabalak, Sara"},{"full_name":"Smalyukh, Ivan I.","first_name":"Ivan I.","last_name":"Smalyukh"},{"full_name":"Tagliazucchi, Mario","first_name":"Mario","last_name":"Tagliazucchi"},{"last_name":"Talapin","first_name":"Dmitri V.","full_name":"Talapin, Dmitri V."},{"last_name":"Tkachenko","first_name":"Alexei V.","full_name":"Tkachenko, Alexei V."},{"first_name":"Sergei","full_name":"Tretiak, Sergei","last_name":"Tretiak"},{"last_name":"Vaknin","full_name":"Vaknin, David","first_name":"David"},{"full_name":"Widmer-Cooper, Asaph","first_name":"Asaph","last_name":"Widmer-Cooper"},{"last_name":"Wong","first_name":"Gerard C.L.","full_name":"Wong, Gerard C.L."},{"last_name":"Ye","full_name":"Ye, Xingchen","first_name":"Xingchen"},{"full_name":"Zhou, Shan","first_name":"Shan","last_name":"Zhou"},{"last_name":"Rabani","full_name":"Rabani, Eran","first_name":"Eran"},{"first_name":"Michael","full_name":"Engel, Michael","last_name":"Engel"},{"last_name":"Travesset","first_name":"Alex","full_name":"Travesset, Alex"}],"publisher":"American Chemical Society","date_published":"2024-05-30T00:00:00Z","article_type":"review","month":"05","date_updated":"2025-09-08T07:52:37Z","publication_status":"published","article_processing_charge":"No","department":[{"_id":"MaIb"}],"oa_version":"None","OA_type":"closed access","publication_identifier":{"issn":["1936-0851"],"eissn":["1936-086X"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2024","issue":"23","status":"public"},{"page":"249-279","author":[{"last_name":"Tairi","first_name":"Erkan","full_name":"Tairi, Erkan"},{"full_name":"Ünal, Akin","first_name":"Akin","id":"f6b56fb6-dc63-11ee-9dbf-f6780863a85a","orcid":"0000-0002-8929-0221","last_name":"Ünal"}],"quality_controlled":"1","doi":"10.1007/978-3-031-58723-8_9","_id":"17126","type":"conference","publication":"Advances in Cryptology – EUROCRYPT 2024","intvolume":"     14652","citation":{"ista":"Tairi E, Ünal A. 2024. Lower bounds for lattice-based compact functional encryption. Advances in Cryptology – EUROCRYPT 2024. EUROCRYPT: Theory and Applications of Cryptographic Techniques, LNCS, vol. 14652, 249–279.","chicago":"Tairi, Erkan, and Akin Ünal. “Lower Bounds for Lattice-Based Compact Functional Encryption.” In <i>Advances in Cryptology – EUROCRYPT 2024</i>, 14652:249–79. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-3-031-58723-8_9\">https://doi.org/10.1007/978-3-031-58723-8_9</a>.","short":"E. Tairi, A. Ünal, in:, Advances in Cryptology – EUROCRYPT 2024, Springer Nature, 2024, pp. 249–279.","mla":"Tairi, Erkan, and Akin Ünal. “Lower Bounds for Lattice-Based Compact Functional Encryption.” <i>Advances in Cryptology – EUROCRYPT 2024</i>, vol. 14652, Springer Nature, 2024, pp. 249–79, doi:<a href=\"https://doi.org/10.1007/978-3-031-58723-8_9\">10.1007/978-3-031-58723-8_9</a>.","ieee":"E. Tairi and A. Ünal, “Lower bounds for lattice-based compact functional encryption,” in <i>Advances in Cryptology – EUROCRYPT 2024</i>, Zurich, Switzerland, 2024, vol. 14652, pp. 249–279.","apa":"Tairi, E., &#38; Ünal, A. (2024). Lower bounds for lattice-based compact functional encryption. In <i>Advances in Cryptology – EUROCRYPT 2024</i> (Vol. 14652, pp. 249–279). Zurich, Switzerland: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-58723-8_9\">https://doi.org/10.1007/978-3-031-58723-8_9</a>","ama":"Tairi E, Ünal A. Lower bounds for lattice-based compact functional encryption. In: <i>Advances in Cryptology – EUROCRYPT 2024</i>. Vol 14652. Springer Nature; 2024:249-279. doi:<a href=\"https://doi.org/10.1007/978-3-031-58723-8_9\">10.1007/978-3-031-58723-8_9</a>"},"acknowledgement":"We want to thank the anonymous reviewers of TCC and Eurocrypt for their very helpful comments and suggestions. This work has received funding from the Austrian Science Fund (FWF) and netidee SCIENCE via grant P31621-N38 (PROFET).","external_id":{"isi":["001278247600009"]},"volume":14652,"title":"Lower bounds for lattice-based compact functional encryption","language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":"https://eprint.iacr.org/2023/719.pdf"}],"day":"08","abstract":[{"text":"Functional encryption (FE) is a primitive where the holder of a master secret key can control which functions a user can evaluate on encrypted data. It is a powerful primitive that even implies indistinguishability obfuscation (iO), given sufficiently compact ciphertexts (Ananth-Jain, CRYPTO’15 and Bitansky-Vaikuntanathan, FOCS’15). However, despite being extensively studied, there are FE schemes, such as function-hiding inner-product FE (Bishop-Jain-Kowalczyk, AC’15, Abdalla-Catalano-Fiore-Gay-Ursu, CRYPTO’18) and compact quadratic FE (Baltico-Catalano-Fiore-Gay, Lin, CRYPTO’17), that can be only realized using pairings. This raises the question if there are some mathematical barriers that hinder us from realizing these FE schemes from other assumptions.\r\n\r\nIn this paper, we study the difficulty of constructing lattice-based compact FE. We generalize the impossibility results of Ünal (EC’20) for lattice-based function-hiding FE, and extend it to the case of compact FE. Concretely, we prove lower bounds for lattice-based compact FE schemes which meet some (natural) algebraic restrictions at encryption and decryption, and have ciphertexts of linear size and secret keys of minimal degree. We see our results as important indications of why it is hard to construct lattice-based FE schemes for new functionalities, and which mathematical barriers have to be overcome.","lang":"eng"}],"date_created":"2024-06-09T22:01:03Z","isi":1,"scopus_import":"1","year":"2024","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"eissn":["1611-3349"],"issn":["0302-9743"],"isbn":["9783031587221"]},"alternative_title":["LNCS"],"oa_version":"Submitted Version","oa":1,"department":[{"_id":"KrPi"}],"conference":{"end_date":"2024-05-30","location":"Zurich, Switzerland","start_date":"2024-05-26","name":"EUROCRYPT: Theory and Applications of Cryptographic Techniques"},"article_processing_charge":"No","month":"05","date_published":"2024-05-08T00:00:00Z","publication_status":"published","date_updated":"2025-09-08T07:48:18Z","publisher":"Springer Nature"},{"quality_controlled":"1","author":[{"orcid":"0000-0002-0704-7026","last_name":"Wang","full_name":"Wang, Victor","first_name":"Victor","id":"76096395-aea4-11ed-a680-ab8ebbd3f1b9"},{"full_name":"Xu, Max Wenqiang","first_name":"Max Wenqiang","last_name":"Xu"}],"page":"2718-2726","doi":"10.1112/blms.13095","_id":"17127","project":[{"call_identifier":"H2020","grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c"}],"type":"journal_article","publication":"Bulletin of the London Mathematical Society","acknowledgement":"We thank Oleksiy Klurman, Ilya Shkredov, and Igor Shparlinski for helpful comments on earlier versions of the paper, and thank Yotam Hendel for providing a reference for Lemma 2.1. We also thank the anonymous referee for their generous corrections and comments. The first author has received funding from the European Union's Horizon 2020 Research and Innovation Program under the Marie Skłodowska-Curie Grant Agreement Number: 101034413. The second author is partially supported by the Cuthbert C. Hurd Graduate Fellowship in the Mathematical Sciences, Stanford.","citation":{"ama":"Wang V, Xu MW. Paucity phenomena for polynomial products. <i>Bulletin of the London Mathematical Society</i>. 2024;56(8):2718-2726. doi:<a href=\"https://doi.org/10.1112/blms.13095\">10.1112/blms.13095</a>","apa":"Wang, V., &#38; Xu, M. W. (2024). Paucity phenomena for polynomial products. <i>Bulletin of the London Mathematical Society</i>. London Mathematical Society. <a href=\"https://doi.org/10.1112/blms.13095\">https://doi.org/10.1112/blms.13095</a>","ieee":"V. Wang and M. W. Xu, “Paucity phenomena for polynomial products,” <i>Bulletin of the London Mathematical Society</i>, vol. 56, no. 8. London Mathematical Society, pp. 2718–2726, 2024.","mla":"Wang, Victor, and Max Wenqiang Xu. “Paucity Phenomena for Polynomial Products.” <i>Bulletin of the London Mathematical Society</i>, vol. 56, no. 8, London Mathematical Society, 2024, pp. 2718–26, doi:<a href=\"https://doi.org/10.1112/blms.13095\">10.1112/blms.13095</a>.","short":"V. Wang, M.W. Xu, Bulletin of the London Mathematical Society 56 (2024) 2718–2726.","chicago":"Wang, Victor, and Max Wenqiang Xu. “Paucity Phenomena for Polynomial Products.” <i>Bulletin of the London Mathematical Society</i>. London Mathematical Society, 2024. <a href=\"https://doi.org/10.1112/blms.13095\">https://doi.org/10.1112/blms.13095</a>.","ista":"Wang V, Xu MW. 2024. Paucity phenomena for polynomial products. Bulletin of the London Mathematical Society. 56(8), 2718–2726."},"external_id":{"arxiv":["2211.02908"],"isi":["001235729900001"]},"ddc":["512"],"arxiv":1,"intvolume":"        56","title":"Paucity phenomena for polynomial products","language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2211.02908"}],"file_date_updated":"2024-08-20T08:36:32Z","volume":56,"abstract":[{"lang":"eng","text":"Let  P(x)∈Z[x] be a polynomial with at least two distinct complex roots. We prove that the number of solutions  (x1,…,xk,y1,…,yk)∈[N]2k to the equation\r\n∏1≤i≤kP(xi)=∏1≤j≤kP(yj)≠0\r\n(for any  k≥1 ) is asymptotically  k!Nk  as  N→+∞. This solves a question first proposed and studied by Najnudel. The result can also be interpreted as saying that all even moments of random partial sums  1N√∑n≤Nf(P(n)) match standard complex Gaussian moments as  N→+∞\r\n , where  f is the Steinhaus random multiplicative function."}],"day":"01","date_created":"2024-06-09T22:01:03Z","scopus_import":"1","isi":1,"issue":"8","status":"public","year":"2024","has_accepted_license":"1","publication_identifier":{"issn":["0024-6093"],"eissn":["1469-2120"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","file":[{"file_id":"17446","relation":"main_file","date_created":"2024-08-20T08:36:32Z","file_name":"Paucity_phenomena_for_polynomial_products__Wang_Xu_ (7).pdf","date_updated":"2024-08-20T08:36:32Z","success":1,"content_type":"application/pdf","checksum":"ae386a4031856efac23c7cdcb53b559b","file_size":331775,"access_level":"open_access","creator":"vwang"}],"oa_version":"Submitted Version","oa":1,"article_processing_charge":"No","department":[{"_id":"TiBr"}],"date_published":"2024-08-01T00:00:00Z","article_type":"original","month":"08","date_updated":"2025-09-08T08:57:32Z","publication_status":"published","publisher":"London Mathematical Society","ec_funded":1},{"oa_version":"None","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"corr_author":"1","year":"2024","status":"public","publisher":"Springer Nature","date_updated":"2025-09-08T07:50:20Z","publication_status":"published","article_type":"original","date_published":"2024-08-01T00:00:00Z","month":"08","department":[{"_id":"BjHo"}],"article_processing_charge":"No","intvolume":"        20","external_id":{"isi":["001232300600001"]},"acknowledgement":"We gratefully acknowledge the assistance of J. M. Lopez with DNSs at an early stage of this work. This work was partially supported by two grants from the Simons Foundation (grant nos. 662985 (N.G.) and 662960 (B.H.)) and by Ministry of Science and Technology, Taiwan (grant nos. MOST 109-2112-M-001-017-MY3 and MOST 111-2112-M-001-027-MY3 (H.-Y.S.)). Part of this work was performed using computing resources of CRIANN (Normandy, France).","citation":{"apa":"Lemoult, G. M., Vasudevan, M., Shih, H. Y., Linga, G., Mathiesen, J., Goldenfeld, N., &#38; Hof, B. (2024). Directed percolation and puff jamming near the transition to pipe turbulence. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-024-02513-0\">https://doi.org/10.1038/s41567-024-02513-0</a>","ama":"Lemoult GM, Vasudevan M, Shih HY, et al. Directed percolation and puff jamming near the transition to pipe turbulence. <i>Nature Physics</i>. 2024;20:1339-1345. doi:<a href=\"https://doi.org/10.1038/s41567-024-02513-0\">10.1038/s41567-024-02513-0</a>","ieee":"G. M. Lemoult <i>et al.</i>, “Directed percolation and puff jamming near the transition to pipe turbulence,” <i>Nature Physics</i>, vol. 20. Springer Nature, pp. 1339–1345, 2024.","mla":"Lemoult, Grégoire M., et al. “Directed Percolation and Puff Jamming near the Transition to Pipe Turbulence.” <i>Nature Physics</i>, vol. 20, Springer Nature, 2024, pp. 1339–45, doi:<a href=\"https://doi.org/10.1038/s41567-024-02513-0\">10.1038/s41567-024-02513-0</a>.","chicago":"Lemoult, Grégoire M, Mukund Vasudevan, Hong Yan Shih, Gaute Linga, Joachim Mathiesen, Nigel Goldenfeld, and Björn Hof. “Directed Percolation and Puff Jamming near the Transition to Pipe Turbulence.” <i>Nature Physics</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41567-024-02513-0\">https://doi.org/10.1038/s41567-024-02513-0</a>.","short":"G.M. Lemoult, M. Vasudevan, H.Y. Shih, G. Linga, J. Mathiesen, N. Goldenfeld, B. Hof, Nature Physics 20 (2024) 1339–1345.","ista":"Lemoult GM, Vasudevan M, Shih HY, Linga G, Mathiesen J, Goldenfeld N, Hof B. 2024. Directed percolation and puff jamming near the transition to pipe turbulence. Nature Physics. 20, 1339–1345."},"publication":"Nature Physics","type":"journal_article","project":[{"name":"Revisiting the Turbulence Problem Using Statistical Mechanics","grant_number":"662960","_id":"238598C6-32DE-11EA-91FC-C7463DDC885E"}],"_id":"17128","doi":"10.1038/s41567-024-02513-0","author":[{"last_name":"Lemoult","id":"4787FE80-F248-11E8-B48F-1D18A9856A87","full_name":"Lemoult, Grégoire M","first_name":"Grégoire M"},{"last_name":"Vasudevan","id":"3C5A959A-F248-11E8-B48F-1D18A9856A87","first_name":"Mukund","full_name":"Vasudevan, Mukund"},{"last_name":"Shih","full_name":"Shih, Hong Yan","first_name":"Hong Yan"},{"first_name":"Gaute","full_name":"Linga, Gaute","last_name":"Linga"},{"last_name":"Mathiesen","full_name":"Mathiesen, Joachim","first_name":"Joachim"},{"full_name":"Goldenfeld, Nigel","first_name":"Nigel","last_name":"Goldenfeld"},{"id":"3A374330-F248-11E8-B48F-1D18A9856A87","full_name":"Hof, Björn","first_name":"Björn","last_name":"Hof","orcid":"0000-0003-2057-2754"}],"page":"1339-1345","quality_controlled":"1","isi":1,"scopus_import":"1","date_created":"2024-06-09T22:01:03Z","day":"01","abstract":[{"text":"The onset of turbulence in pipe flow has defied detailed understanding ever since the first observations of the spatially heterogeneous nature of the transition. Recent theoretical studies and experiments in simpler, shear-driven flows suggest that the onset of turbulence is a directed-percolation non-equilibrium phase transition, but whether these findings are generic and also apply to open or pressure-driven flows is unknown. In pipe flow, the extremely long time scales near the transition make direct observations of critical behaviour virtually impossible. Here we find a technical solution to that limitation and show that the universality class of the transition is directed percolation, from which a jammed phase of puffs emerges above the critical point. Our method is to experimentally characterize all pairwise interactions between localized patches of turbulence puffs and use these interactions as input for renormalization group and computer simulations of minimal models that extrapolate to long length and time scales. The strong interactions in the jamming regime enable us to explicitly measure the turbulent fraction and confirm model predictions. Our work shows that directed-percolation scaling applies beyond simple closed shear flows and underscores how statistical mechanics can lead to profound, quantitative and predictive insights on turbulent flows and their phases.","lang":"eng"}],"volume":20,"language":[{"iso":"eng"}],"title":"Directed percolation and puff jamming near the transition to pipe turbulence"},{"date_created":"2024-06-11T18:20:05Z","abstract":[{"lang":"eng","text":"An ideal quantum computer relies on qubits capable of performing fast gate operations and\r\nmaintaining strong interconnections while preserving their quantum coherence. Since the\r\ninception of experimental eforts toward building a quantum computer, the community has\r\nfaced challenges in engineering such a system. Among the various methods of implementing a\r\nquantum computer, superconducting qubits have shown fast gates close to tens of nanoseconds,\r\nwith the state-of-the-art reaching a coherence of a few milliseconds. However, achieving\r\nsimultaneously long lifetimes with fast qubit operations poses an inherent paradox. Qubits\r\nwith high coherence require isolation from the environment, while fast operation necessitates\r\nstrong coupling of the qubit. This thesis approaches this issue by proposing the idea of\r\nengineering superconducting qubits capable of transitioning between operating in a protected\r\nregime, where the qubit is completely isolated from the environment, and coupling to the\r\ncommunication channels as needed. In this direction, we use the geometric superinductor to\r\nscan the parameter space of rf-SQUID devices, searching for a regime where we can take the\r\nqubit protection to its extreme.\r\n\r\nThis leads us to the inductively shunted transmon (IST) regime, characterized by EJ /EC ≫ 1\r\nand EJ /EL ≫ 1, where the circuit potential exhibits a double well with a large barrier\r\nseparating the local ground states of each quantum well. In this regime, although it is\r\nanticipated that the two quantum wells would be isolated from each other, we observe single\r\nfuxon tunneling between them. The interplay of the cavity photons and the fuxon transition\r\nforms a rich physical system, containing resonance conditions that allow the preparation of the\r\nfuxon ground or excited states. This enables us to study the relaxation rate of such transition\r\nand show that it can be as large as 3.6 hours. Dynamically controlling the barrier height\r\nbetween the two quantum wells allows for controllable coupling, which scales exponentially,\r\nfor a qubit encoded in two fuxon states.\r\nThe 0-π qubit is one of the very few known superconducting circuit types that ofers exponential\r\nprotection from both relaxation and dephasing simultaneously. However, this qubit is not\r\nexempt from the fact that such protection comes at the expense of complex readout and\r\ncontrol. In this thesis, we propose a way to controllably break the circuit symmetry, the\r\nkey reason for the protection, to momentarily restore the ability to control and manipulate\r\nthe qubit. An asymmetry in capacitances and inductances in the 0-π circuit is detrimental\r\nsince they lead to coupling of the protected state to the thermally occupied parasitic mode\r\nof the circuit. However, here we try to exploit a controlled asymmetry in Josephson energies\r\nand show that this can be used as a tunable coupler between the protected states. In the\r\nfuture, this should allow to perform gate operations by dynamically controlling the asymmetry\r\ninstead of driving the protected transition with microwave pulses. Therefore, we believe that\r\nthe proposed method can make the use of protected qubits more practical in experimental\r\nrealizations of quantum computing."}],"day":"11","related_material":{"record":[{"status":"public","id":"13227","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"9928","status":"public"},{"id":"8755","relation":"part_of_dissertation","status":"public"}]},"language":[{"iso":"eng"}],"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","title":"Superconducting qubits capable of dynamic switching between protected and high-speed control regimes","keyword":["Quantum information","Qubits","Superconducting devices"],"file_date_updated":"2024-06-20T11:52:22Z","supervisor":[{"first_name":"Johannes M","full_name":"Fink, Johannes M","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8112-028X","last_name":"Fink"}],"_id":"17133","doi":"10.15479/at:ista:17133","project":[{"name":"NOMIS Fellowship Program","_id":"9B861AAC-BA93-11EA-9121-9846C619BF3A"},{"_id":"bdb108fd-d553-11ed-ba76-83dc74a9864f","name":"QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration of Superconducting Quantum Circuits","grant_number":"F07105"}],"author":[{"orcid":"0000-0001-6937-5773","last_name":"Hassani","first_name":"Farid","full_name":"Hassani, Farid","id":"2AED110C-F248-11E8-B48F-1D18A9856A87"}],"page":"161","ddc":["530"],"citation":{"ista":"Hassani F. 2024. Superconducting qubits capable of dynamic switching between protected and high-speed control regimes. Institute of Science and Technology Austria.","chicago":"Hassani, Farid. “Superconducting Qubits Capable of Dynamic Switching between Protected and High-Speed Control Regimes.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:17133\">https://doi.org/10.15479/at:ista:17133</a>.","short":"F. Hassani, Superconducting Qubits Capable of Dynamic Switching between Protected and High-Speed Control Regimes, Institute of Science and Technology Austria, 2024.","mla":"Hassani, Farid. <i>Superconducting Qubits Capable of Dynamic Switching between Protected and High-Speed Control Regimes</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:17133\">10.15479/at:ista:17133</a>.","ieee":"F. Hassani, “Superconducting qubits capable of dynamic switching between protected and high-speed control regimes,” Institute of Science and Technology Austria, 2024.","apa":"Hassani, F. (2024). <i>Superconducting qubits capable of dynamic switching between protected and high-speed control regimes</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:17133\">https://doi.org/10.15479/at:ista:17133</a>","ama":"Hassani F. Superconducting qubits capable of dynamic switching between protected and high-speed control regimes. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:17133\">10.15479/at:ista:17133</a>"},"type":"dissertation","article_processing_charge":"No","department":[{"_id":"GradSch"},{"_id":"JoFi"}],"oa":1,"publisher":"Institute of Science and Technology Austria","acknowledged_ssus":[{"_id":"NanoFab"},{"_id":"M-Shop"}],"publication_status":"published","date_updated":"2026-04-15T06:43:02Z","date_published":"2024-06-11T00:00:00Z","month":"06","corr_author":"1","has_accepted_license":"1","status":"public","year":"2024","degree_awarded":"PhD","oa_version":"Published Version","file":[{"creator":"fhassani","access_level":"open_access","file_size":28370759,"checksum":"258c353d47fa37ea63ea43b1e10a34a0","content_type":"application/pdf","date_updated":"2024-06-20T11:52:22Z","relation":"main_file","file_name":"Thesis_main_final.pdf","date_created":"2024-06-12T07:53:19Z","file_id":"17137"},{"file_name":"Thesis_main.tex","date_created":"2024-06-12T07:54:27Z","relation":"source_file","file_id":"17138","creator":"fhassani","file_size":445735,"checksum":"deffa5d0db88093f74812fa71520d5e1","access_level":"closed","content_type":"text/x-tex","date_updated":"2024-06-12T07:54:27Z"}],"alternative_title":["ISTA Thesis"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-040-4"]},"OA_place":"publisher","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd"},{"pmid":1,"isi":1,"scopus_import":"1","date_created":"2024-06-15T19:50:15Z","day":"27","abstract":[{"lang":"eng","text":"The TIR1/AFB–Aux/IAA–ARF canonical auxin signaling pathway is widely accepted to (de)active transcriptional regulation, thus controlling auxin-associated developmental processes. However, the theme of a rapid auxin response has emerged since the 2018 Auxins and Cytokinin in Plant Development conference. To date, a few signaling components have been identified to mediate both slow and rapid auxin responses, which unveils the complexity of auxin signaling."}],"volume":75,"file_date_updated":"2025-01-02T10:26:22Z","language":[{"iso":"eng"}],"title":"Slow and rapid auxin responses in Arabidopsis","intvolume":"        75","external_id":{"isi":["001270051200001"],"pmid":["38794966"]},"ddc":["580"],"acknowledgement":"We thank other lab members for their critical comments on this manuscript. We also thank the editor and reviewers for their constructive comments to improve our manuscript. We apologize to authors whose important work we could not include due to space limitations.\r\nThis work is supported by funding from Jiangxi Agricultural University (9232308314) and the Science and Technology Department of Jiangxi Province (20223BCJ25037) to HBH, and the Science and Technology Department of Jiangxi Province (20202ACB215002) to SYP.","citation":{"apa":"Zhang, Z., Chen, H., Peng, S., &#38; Han, H. (2024). Slow and rapid auxin responses in Arabidopsis. <i>Journal of Experimental Botany</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/jxb/erae246\">https://doi.org/10.1093/jxb/erae246</a>","ama":"Zhang Z, Chen H, Peng S, Han H. Slow and rapid auxin responses in Arabidopsis. <i>Journal of Experimental Botany</i>. 2024;75(18). doi:<a href=\"https://doi.org/10.1093/jxb/erae246\">10.1093/jxb/erae246</a>","mla":"Zhang, Zilin, et al. “Slow and Rapid Auxin Responses in Arabidopsis.” <i>Journal of Experimental Botany</i>, vol. 75, no. 18, erae246, Oxford University Press, 2024, doi:<a href=\"https://doi.org/10.1093/jxb/erae246\">10.1093/jxb/erae246</a>.","ieee":"Z. Zhang, H. Chen, S. Peng, and H. Han, “Slow and rapid auxin responses in Arabidopsis,” <i>Journal of Experimental Botany</i>, vol. 75, no. 18. Oxford University Press, 2024.","chicago":"Zhang, Zilin, Huihuang Chen, Shuaiying Peng, and Huibin Han. “Slow and Rapid Auxin Responses in Arabidopsis.” <i>Journal of Experimental Botany</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/jxb/erae246\">https://doi.org/10.1093/jxb/erae246</a>.","short":"Z. Zhang, H. Chen, S. Peng, H. Han, Journal of Experimental Botany 75 (2024).","ista":"Zhang Z, Chen H, Peng S, Han H. 2024. Slow and rapid auxin responses in Arabidopsis. Journal of Experimental Botany. 75(18), erae246."},"publication":"Journal of Experimental Botany","type":"journal_article","_id":"17141","doi":"10.1093/jxb/erae246","author":[{"full_name":"Zhang, Zilin","first_name":"Zilin","last_name":"Zhang"},{"last_name":"Chen","full_name":"Chen, Huihuang","first_name":"Huihuang","id":"83c96512-15b2-11ec-abd3-b7eede36184f"},{"last_name":"Peng","full_name":"Peng, Shuaiying","first_name":"Shuaiying"},{"last_name":"Han","full_name":"Han, Huibin","first_name":"Huibin"}],"quality_controlled":"1","publisher":"Oxford University Press","publication_status":"published","date_updated":"2025-09-08T07:57:50Z","date_published":"2024-09-27T00:00:00Z","month":"09","article_type":"original","article_number":"erae246","department":[{"_id":"GradSch"},{"_id":"JiFr"}],"article_processing_charge":"No","oa":1,"OA_type":"hybrid","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"date_updated":"2025-01-02T10:26:22Z","content_type":"application/pdf","access_level":"open_access","checksum":"91b9435ed0f6640809c7588df19abf2f","file_size":763097,"creator":"dernst","success":1,"file_id":"18720","date_created":"2025-01-02T10:26:22Z","file_name":"2024_JourExperimentalBotany_Zhang.pdf","relation":"main_file"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"issn":["0022-0957"]},"OA_place":"publisher","has_accepted_license":"1","year":"2024","status":"public","issue":"18"},{"intvolume":"        22","external_id":{"pmid":["38857283"],"isi":["001246176800003"]},"ddc":["570"],"acknowledgement":"This work was supported by a European Research Council Starting Grant 756502 (MJ). ","citation":{"short":"L. Burnett, P. Koppensteiner, O. Symonova, T. Masson, T.A. Vega Zuniga, X. Contreras, T. Rülicke, R. Shigemoto, G. Novarino, M.A. Jösch, PLoS Biology 22 (2024).","chicago":"Burnett, Laura, Peter Koppensteiner, Olga Symonova, Tomas Masson, Tomas A Vega Zuniga, Ximena Contreras, Thomas Rülicke, Ryuichi Shigemoto, Gaia Novarino, and Maximilian A Jösch. “Shared Behavioural Impairments in Visual Perception and Place Avoidance across Different Autism Models Are Driven by Periaqueductal Grey Hypoexcitability in Setd5 Haploinsufficient Mice.” <i>PLoS Biology</i>. Public Library of Science, 2024. <a href=\"https://doi.org/10.1371/journal.pbio.3002668\">https://doi.org/10.1371/journal.pbio.3002668</a>.","ista":"Burnett L, Koppensteiner P, Symonova O, Masson T, Vega Zuniga TA, Contreras X, Rülicke T, Shigemoto R, Novarino G, Jösch MA. 2024. Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice. PLoS Biology. 22, e3002668.","ama":"Burnett L, Koppensteiner P, Symonova O, et al. Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice. <i>PLoS Biology</i>. 2024;22. doi:<a href=\"https://doi.org/10.1371/journal.pbio.3002668\">10.1371/journal.pbio.3002668</a>","apa":"Burnett, L., Koppensteiner, P., Symonova, O., Masson, T., Vega Zuniga, T. A., Contreras, X., … Jösch, M. A. (2024). Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.3002668\">https://doi.org/10.1371/journal.pbio.3002668</a>","ieee":"L. Burnett <i>et al.</i>, “Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice,” <i>PLoS Biology</i>, vol. 22. Public Library of Science, 2024.","mla":"Burnett, Laura, et al. “Shared Behavioural Impairments in Visual Perception and Place Avoidance across Different Autism Models Are Driven by Periaqueductal Grey Hypoexcitability in Setd5 Haploinsufficient Mice.” <i>PLoS Biology</i>, vol. 22, e3002668, Public Library of Science, 2024, doi:<a href=\"https://doi.org/10.1371/journal.pbio.3002668\">10.1371/journal.pbio.3002668</a>."},"publication":"PLoS Biology","type":"journal_article","project":[{"_id":"2634E9D2-B435-11E9-9278-68D0E5697425","name":"Circuits of Visual Attention","call_identifier":"H2020","grant_number":"756502"}],"_id":"17142","doi":"10.1371/journal.pbio.3002668","author":[{"id":"3B717F68-F248-11E8-B48F-1D18A9856A87","full_name":"Burnett, Laura","first_name":"Laura","last_name":"Burnett","orcid":"0000-0002-8937-410X"},{"id":"3B8B25A8-F248-11E8-B48F-1D18A9856A87","full_name":"Koppensteiner, Peter","first_name":"Peter","last_name":"Koppensteiner","orcid":"0000-0002-3509-1948"},{"id":"3C0C7BC6-F248-11E8-B48F-1D18A9856A87","full_name":"Symonova, Olga","first_name":"Olga","last_name":"Symonova","orcid":"0000-0003-2012-9947"},{"last_name":"Masson","orcid":"0000-0002-2634-6283","id":"93ac43e8-8599-11eb-9b86-f6efb0a4c207","full_name":"Masson, Tomas","first_name":"Tomas"},{"last_name":"Vega Zuniga","id":"2E7C4E78-F248-11E8-B48F-1D18A9856A87","first_name":"Tomas A","full_name":"Vega Zuniga, Tomas A"},{"last_name":"Contreras","first_name":"Ximena","full_name":"Contreras, Ximena","id":"475990FE-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Rülicke, Thomas","first_name":"Thomas","last_name":"Rülicke"},{"first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8761-9444","last_name":"Shigemoto"},{"orcid":"0000-0002-7673-7178","last_name":"Novarino","first_name":"Gaia","full_name":"Novarino, Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-3937-1330","last_name":"Jösch","first_name":"Maximilian A","full_name":"Jösch, Maximilian A","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87"}],"quality_controlled":"1","pmid":1,"isi":1,"scopus_import":"1","date_created":"2024-06-16T22:01:05Z","abstract":[{"text":"Despite the diverse genetic origins of autism spectrum disorders (ASDs), affected individuals share strikingly similar and correlated behavioural traits that include perceptual and sensory processing challenges. Notably, the severity of these sensory symptoms is often predictive of the expression of other autistic traits. However, the origin of these perceptual deficits remains largely elusive. Here, we show a recurrent impairment in visual threat perception that is similarly impaired in 3 independent mouse models of ASD with different molecular aetiologies. Interestingly, this deficit is associated with reduced avoidance of threatening environments—a nonperceptual trait. Focusing on a common cause of ASDs, the Setd5 gene mutation, we define the molecular mechanism. We show that the perceptual impairment is caused by a potassium channel (Kv1)-mediated hypoexcitability in a subcortical node essential for the initiation of escape responses, the dorsal periaqueductal grey (dPAG). Targeted pharmacological Kv1 blockade rescued both perceptual and place avoidance deficits, causally linking seemingly unrelated trait deficits to the dPAG. Furthermore, we show that different molecular mechanisms converge on similar behavioural phenotypes by demonstrating that the autism models Cul3 and Ptchd1, despite having similar behavioural phenotypes, differ in their functional and molecular alteration. Our findings reveal a link between rapid perception controlled by subcortical pathways and appropriate learned interactions with the environment and define a nondevelopmental source of such deficits in ASD.","lang":"eng"}],"day":"10","volume":22,"file_date_updated":"2025-01-09T10:39:41Z","related_material":{"record":[{"status":"public","relation":"research_data","id":"15385"}],"link":[{"url":"https://doi.org/10.5281/zenodo.11130587","relation":"software"}]},"language":[{"iso":"eng"}],"DOAJ_listed":"1","title":"Shared behavioural impairments in visual perception and place avoidance across different autism models are driven by periaqueductal grey hypoexcitability in Setd5 haploinsufficient mice","OA_type":"gold","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","file":[{"file_id":"18805","file_name":"2024_PloS_Burnett.pdf","date_created":"2025-01-09T10:39:41Z","relation":"main_file","date_updated":"2025-01-09T10:39:41Z","creator":"dernst","access_level":"open_access","file_size":4016568,"checksum":"496e1aa4fd5b92b7e4087ecc2c964133","content_type":"application/pdf","success":1}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"eissn":["1545-7885"],"issn":["1544-9173"]},"OA_place":"publisher","has_accepted_license":"1","corr_author":"1","year":"2024","status":"public","ec_funded":1,"publisher":"Public Library of Science","publication_status":"published","APC_amount":"6081,83 EUR","date_updated":"2025-09-08T07:57:11Z","date_published":"2024-06-10T00:00:00Z","month":"06","article_type":"original","article_number":"e3002668","department":[{"_id":"RySh"},{"_id":"GaNo"},{"_id":"MaJö"}],"article_processing_charge":"Yes","oa":1},{"page":"3779-3804","author":[{"first_name":"Lorenzo","full_name":"Dello Schiavo, Lorenzo","id":"ECEBF480-9E4F-11EA-B557-B0823DDC885E","orcid":"0000-0002-9881-6870","last_name":"Dello Schiavo"},{"orcid":"0000-0002-0845-1338","last_name":"Maas","full_name":"Maas, Jan","first_name":"Jan","id":"4C5696CE-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Pedrotti","full_name":"Pedrotti, Francesco","first_name":"Francesco","id":"d3ac8ac6-dc8d-11ea-abe3-e2a9628c4c3c"}],"quality_controlled":"1","project":[{"name":"Optimal Transport and Stochastic Dynamics","grant_number":"716117","call_identifier":"H2020","_id":"256E75B8-B435-11E9-9278-68D0E5697425"},{"name":"Taming Complexity in Partial Differential Systems","grant_number":"F6504","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"},{"grant_number":"E208","name":"Configuration Spaces over Non-Smooth Spaces","_id":"34dbf174-11ca-11ed-8bc3-afe9d43d4b9c"}],"doi":"10.1090/tran/9156","_id":"17143","type":"journal_article","publication":"Transactions of the American Mathematical Society","arxiv":1,"intvolume":"       377","citation":{"ieee":"L. Dello Schiavo, J. Maas, and F. Pedrotti, “Local conditions for global convergence of gradient flows and proximal point sequences in metric spaces,” <i>Transactions of the American Mathematical Society</i>, vol. 377, no. 6. American Mathematical Society, pp. 3779–3804, 2024.","mla":"Dello Schiavo, Lorenzo, et al. “Local Conditions for Global Convergence of Gradient Flows and Proximal Point Sequences in Metric Spaces.” <i>Transactions of the American Mathematical Society</i>, vol. 377, no. 6, American Mathematical Society, 2024, pp. 3779–804, doi:<a href=\"https://doi.org/10.1090/tran/9156\">10.1090/tran/9156</a>.","apa":"Dello Schiavo, L., Maas, J., &#38; Pedrotti, F. (2024). Local conditions for global convergence of gradient flows and proximal point sequences in metric spaces. <i>Transactions of the American Mathematical Society</i>. American Mathematical Society. <a href=\"https://doi.org/10.1090/tran/9156\">https://doi.org/10.1090/tran/9156</a>","ama":"Dello Schiavo L, Maas J, Pedrotti F. Local conditions for global convergence of gradient flows and proximal point sequences in metric spaces. <i>Transactions of the American Mathematical Society</i>. 2024;377(6):3779-3804. doi:<a href=\"https://doi.org/10.1090/tran/9156\">10.1090/tran/9156</a>","ista":"Dello Schiavo L, Maas J, Pedrotti F. 2024. Local conditions for global convergence of gradient flows and proximal point sequences in metric spaces. Transactions of the American Mathematical Society. 377(6), 3779–3804.","chicago":"Dello Schiavo, Lorenzo, Jan Maas, and Francesco Pedrotti. “Local Conditions for Global Convergence of Gradient Flows and Proximal Point Sequences in Metric Spaces.” <i>Transactions of the American Mathematical Society</i>. American Mathematical Society, 2024. <a href=\"https://doi.org/10.1090/tran/9156\">https://doi.org/10.1090/tran/9156</a>.","short":"L. Dello Schiavo, J. Maas, F. Pedrotti, Transactions of the American Mathematical Society 377 (2024) 3779–3804."},"acknowledgement":"The authors gratefully acknowledges support by the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 716117). This research was funded in part by the Austrian Science Fund (FWF) project 10.55776/ESP208. This research was funded in part by the Austrian Science Fund (FWF) project 10.55776/F65","external_id":{"arxiv":["2304.05239"],"isi":["001203273300001"]},"volume":377,"title":"Local conditions for global convergence of gradient flows and proximal point sequences in metric spaces","language":[{"iso":"eng"}],"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2304.05239","open_access":"1"}],"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"17336"}]},"day":"01","abstract":[{"text":"This paper deals with local criteria for the convergence to a global minimiser for gradient flow trajectories and their discretisations. To obtain quantitative estimates on the speed of convergence, we consider variations on the classical Kurdyka–Łojasiewicz inequality for a large class of parameter functions. Our assumptions are given in terms of the initial data, without any reference to an equilibrium point. The main results are convergence statements for gradient flow curves and proximal point sequences to a global minimiser, together with sharp quantitative estimates on the speed of convergence. These convergence results apply in the general setting of lower semicontinuous functionals on complete metric spaces, generalising recent results for smooth functionals on Rn. While the non-smooth setting covers very general spaces, it is also useful for (non)-smooth functionals on Rn.\r\n.","lang":"eng"}],"date_created":"2024-06-16T22:01:06Z","isi":1,"scopus_import":"1","year":"2024","status":"public","issue":"6","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","publication_identifier":{"issn":["0002-9947"],"eissn":["1088-6850"]},"oa_version":"Preprint","oa":1,"department":[{"_id":"JaMa"}],"article_processing_charge":"No","date_published":"2024-06-01T00:00:00Z","month":"06","article_type":"original","publication_status":"published","date_updated":"2026-04-07T13:00:02Z","ec_funded":1,"publisher":"American Mathematical Society"},{"oa_version":"Published Version","alternative_title":["LIPIcs"],"file":[{"file_name":"2024_LIPICS_Kourimska.pdf","date_created":"2024-06-17T08:33:40Z","relation":"main_file","file_id":"17150","creator":"dernst","checksum":"b40ff456c19294adb5d9613fcfd751c6","access_level":"open_access","content_type":"application/pdf","file_size":1612558,"success":1,"date_updated":"2024-06-17T08:33:40Z"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_identifier":{"issn":["1868-8969"],"isbn":["9783959773164"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","year":"2024","status":"public","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","ec_funded":1,"publication_status":"published","date_updated":"2025-04-15T07:16:58Z","month":"06","date_published":"2024-06-01T00:00:00Z","article_processing_charge":"No","department":[{"_id":"HeEd"}],"conference":{"end_date":"2024-06-14","location":"Athens, Greece","name":"SoCG: Symposium on Computational Geometry"},"article_number":"69","oa":1,"external_id":{"arxiv":["2212.01118"]},"ddc":["510"],"acknowledgement":"This research has been supported by the European Research Council (ERC), grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund (FWF), grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), grant No. I 02979-N35.\r\nSupported by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 754411, the Austrian science fund (FWF) grant No. M-3073, and the welcome package from IDEX of the Université Cô d'Azur.\r\nWe are greatly indebted to Fred Chazal for sharing his insights. We further thank Erin Chambers, Christopher Fillmore, and Elizabeth Stephenson for early discussions and all members of the Edelsbrunner group (Institute of Science and Technology Austria) and the Datashape team (Inria) for the atmosphere in which this research was conducted.","citation":{"apa":"Kourimska, H., Lieutier, A., &#38; Wintraecken, M. (2024). The medial axis of any closed bounded set Is Lipschitz stable with respect to the Hausdorff distance Under ambient diffeomorphisms. In <i>40th International Symposium on Computational Geometry</i> (Vol. 293). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.69\">https://doi.org/10.4230/LIPIcs.SoCG.2024.69</a>","ama":"Kourimska H, Lieutier A, Wintraecken M. The medial axis of any closed bounded set Is Lipschitz stable with respect to the Hausdorff distance Under ambient diffeomorphisms. In: <i>40th International Symposium on Computational Geometry</i>. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.69\">10.4230/LIPIcs.SoCG.2024.69</a>","ieee":"H. Kourimska, A. Lieutier, and M. Wintraecken, “The medial axis of any closed bounded set Is Lipschitz stable with respect to the Hausdorff distance Under ambient diffeomorphisms,” in <i>40th International Symposium on Computational Geometry</i>, Athens, Greece, 2024, vol. 293.","mla":"Kourimska, Hana, et al. “The Medial Axis of Any Closed Bounded Set Is Lipschitz Stable with Respect to the Hausdorff Distance Under Ambient Diffeomorphisms.” <i>40th International Symposium on Computational Geometry</i>, vol. 293, 69, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.69\">10.4230/LIPIcs.SoCG.2024.69</a>.","chicago":"Kourimska, Hana, André Lieutier, and Mathijs Wintraecken. “The Medial Axis of Any Closed Bounded Set Is Lipschitz Stable with Respect to the Hausdorff Distance Under Ambient Diffeomorphisms.” In <i>40th International Symposium on Computational Geometry</i>, Vol. 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.69\">https://doi.org/10.4230/LIPIcs.SoCG.2024.69</a>.","short":"H. Kourimska, A. Lieutier, M. Wintraecken, in:, 40th International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024.","ista":"Kourimska H, Lieutier A, Wintraecken M. 2024. The medial axis of any closed bounded set Is Lipschitz stable with respect to the Hausdorff distance Under ambient diffeomorphisms. 40th International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 293, 69."},"intvolume":"       293","arxiv":1,"type":"conference","publication":"40th International Symposium on Computational Geometry","_id":"17144","doi":"10.4230/LIPIcs.SoCG.2024.69","project":[{"grant_number":"788183","call_identifier":"H2020","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425"},{"_id":"268116B8-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"Z00342","name":"Mathematics, Computer Science"},{"name":"Persistence and stability of geometric complexes","call_identifier":"FWF","grant_number":"I02979-N35","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","grant_number":"754411"},{"grant_number":"M03073","name":"Learning and triangulating manifolds via collapses","_id":"fc390959-9c52-11eb-aca3-afa58bd282b2"}],"quality_controlled":"1","author":[{"id":"D9B8E14C-3C26-11EA-98F5-1F833DDC885E","first_name":"Hana","full_name":"Kourimska, Hana","last_name":"Kourimska","orcid":"0000-0001-7841-0091"},{"last_name":"Lieutier","first_name":"André","full_name":"Lieutier, André"},{"id":"307CFBC8-F248-11E8-B48F-1D18A9856A87","full_name":"Wintraecken, Mathijs","first_name":"Mathijs","last_name":"Wintraecken","orcid":"0000-0002-7472-2220"}],"scopus_import":"1","date_created":"2024-06-16T22:01:06Z","abstract":[{"text":"We prove that the medial axis of closed sets is Hausdorff stable in the following sense: Let 𝒮 ⊆ ℝ^d be a fixed closed set that contains a bounding sphere. That is, the bounding sphere is part of the set 𝒮. Consider the space of C^{1,1} diffeomorphisms of ℝ^d to itself, which keep the bounding sphere invariant. The map from this space of diffeomorphisms (endowed with a Banach norm) to the space of closed subsets of ℝ^d (endowed with the Hausdorff distance), mapping a diffeomorphism F to the closure of the medial axis of F(𝒮), is Lipschitz. This extends a previous stability result of Chazal and Soufflet on the stability of the medial axis of C² manifolds under C² ambient diffeomorphisms.","lang":"eng"}],"day":"01","language":[{"iso":"eng"}],"title":"The medial axis of any closed bounded set Is Lipschitz stable with respect to the Hausdorff distance Under ambient diffeomorphisms","volume":293,"file_date_updated":"2024-06-17T08:33:40Z"},{"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","date_updated":"2024-06-17T08:41:56Z","publication_status":"published","date_published":"2024-06-01T00:00:00Z","month":"06","article_processing_charge":"No","article_number":"76","conference":{"end_date":"2024-06-14","location":"Athens, Greece","start_date":"2024-06-11","name":"SoCG: Symposium on Computational Geometry"},"department":[{"_id":"HeEd"}],"oa":1,"oa_version":"Published Version","alternative_title":["LIPIcs"],"file":[{"date_updated":"2024-06-17T08:40:04Z","success":1,"creator":"dernst","content_type":"application/pdf","checksum":"fbad1de06383a6b7e8a1cb3e8c7205ce","file_size":1430896,"access_level":"open_access","file_id":"17151","relation":"main_file","file_name":"2024_LIPICS_Rote.pdf","date_created":"2024-06-17T08:40:04Z"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_identifier":{"isbn":["9783959773164"],"issn":["1868-8969"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","status":"public","year":"2024","scopus_import":"1","date_created":"2024-06-16T22:01:06Z","abstract":[{"lang":"eng","text":"Grid peeling is the process of repeatedly removing the convex hull vertices of the grid points that lie inside a given convex curve. It has been conjectured that, for a more and more refined grid, grid peeling converges to a continuous process, the affine curve-shortening flow, which deforms the curve based on the curvature. We prove this conjecture for one class of curves, parabolas with a vertical axis, and we determine the value of the constant factor in the formula that relates the two processes."}],"day":"01","language":[{"iso":"eng"}],"title":"Grid peeling of parabolas","volume":293,"file_date_updated":"2024-06-17T08:40:04Z","external_id":{"arxiv":["2402.15787"]},"ddc":["510"],"citation":{"ama":"Rote G, Rüber M, Saghafian M. Grid peeling of parabolas. In: <i>40th International Symposium on Computational Geometry</i>. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.76\">10.4230/LIPIcs.SoCG.2024.76</a>","apa":"Rote, G., Rüber, M., &#38; Saghafian, M. (2024). Grid peeling of parabolas. In <i>40th International Symposium on Computational Geometry</i> (Vol. 293). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.76\">https://doi.org/10.4230/LIPIcs.SoCG.2024.76</a>","ieee":"G. Rote, M. Rüber, and M. Saghafian, “Grid peeling of parabolas,” in <i>40th International Symposium on Computational Geometry</i>, Athens, Greece, 2024, vol. 293.","mla":"Rote, Günter, et al. “Grid Peeling of Parabolas.” <i>40th International Symposium on Computational Geometry</i>, vol. 293, 76, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.76\">10.4230/LIPIcs.SoCG.2024.76</a>.","short":"G. Rote, M. Rüber, M. Saghafian, in:, 40th International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024.","chicago":"Rote, Günter, Moritz Rüber, and Morteza Saghafian. “Grid Peeling of Parabolas.” In <i>40th International Symposium on Computational Geometry</i>, Vol. 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.76\">https://doi.org/10.4230/LIPIcs.SoCG.2024.76</a>.","ista":"Rote G, Rüber M, Saghafian M. 2024. Grid peeling of parabolas. 40th International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 293, 76."},"acknowledgement":"Part of this work was done while G.R. enjoyed the hospitality of the Institute of Science and Technology Austria (ISTA) as a visiting professor during his sabbatical in the winter semester 2022/23.","intvolume":"       293","arxiv":1,"type":"conference","publication":"40th International Symposium on Computational Geometry","_id":"17145","doi":"10.4230/LIPIcs.SoCG.2024.76","quality_controlled":"1","author":[{"first_name":"Günter","full_name":"Rote, Günter","last_name":"Rote"},{"last_name":"Rüber","first_name":"Moritz","full_name":"Rüber, Moritz"},{"last_name":"Saghafian","first_name":"Morteza","full_name":"Saghafian, Morteza","id":"f86f7148-b140-11ec-9577-95435b8df824"}]},{"date_published":"2024-06-01T00:00:00Z","month":"06","publication_status":"published","date_updated":"2025-12-01T15:19:20Z","ec_funded":1,"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","oa":1,"department":[{"_id":"HeEd"}],"conference":{"end_date":"2024-06-14","location":"Athens, Greece","start_date":"2024-06-11","name":"SoCG: Symposium on Computational Geometry"},"article_number":"53","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1868-8969"],"isbn":["9783959773164"]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"file":[{"relation":"main_file","file_name":"2024_LIPICS_Edelsbrunner.pdf","date_created":"2024-06-17T08:46:33Z","file_id":"17152","success":1,"creator":"dernst","content_type":"application/pdf","access_level":"open_access","file_size":766562,"checksum":"5442d44fb89d77477a87668d6e61aac9","date_updated":"2024-06-17T08:46:33Z"}],"alternative_title":["LIPIcs"],"oa_version":"Published Version","year":"2024","status":"public","has_accepted_license":"1","scopus_import":"1","file_date_updated":"2024-06-17T08:46:33Z","volume":293,"title":"Maximum Betti numbers of Čech complexes","language":[{"iso":"eng"}],"related_material":{"record":[{"status":"public","id":"20657","relation":"later_version"}]},"abstract":[{"text":"The Upper Bound Theorem for convex polytopes implies that the p-th Betti number of the Čech complex of any set of N points in ℝ^d and any radius satisfies β_p = O(N^m), with m = min{p+1, ⌈d/2⌉}. We construct sets in even and odd dimensions, which prove that this upper bound is asymptotically tight. For example, we describe a set of N = 2(n+1) points in ℝ³ and two radii such that the first Betti number of the Čech complex at one radius is (n+1)² - 1, and the second Betti number of the Čech complex at the other radius is n². In particular, there is an arrangement of n contruent balls in ℝ³ that enclose a quadratic number of voids, which answers a long-standing open question in computational geometry.","lang":"eng"}],"day":"01","date_created":"2024-06-16T22:01:06Z","type":"conference","publication":"40th International Symposium on Computational Geometry","arxiv":1,"intvolume":"       293","citation":{"ista":"Edelsbrunner H, Pach J. 2024. Maximum Betti numbers of Čech complexes. 40th International Symposium on Computational Geometry. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 293, 53.","chicago":"Edelsbrunner, Herbert, and János Pach. “Maximum Betti Numbers of Čech Complexes.” In <i>40th International Symposium on Computational Geometry</i>, Vol. 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.53\">https://doi.org/10.4230/LIPIcs.SoCG.2024.53</a>.","short":"H. Edelsbrunner, J. Pach, in:, 40th International Symposium on Computational Geometry, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024.","mla":"Edelsbrunner, Herbert, and János Pach. “Maximum Betti Numbers of Čech Complexes.” <i>40th International Symposium on Computational Geometry</i>, vol. 293, 53, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2024, doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.53\">10.4230/LIPIcs.SoCG.2024.53</a>.","ieee":"H. Edelsbrunner and J. Pach, “Maximum Betti numbers of Čech complexes,” in <i>40th International Symposium on Computational Geometry</i>, Athens, Greece, 2024, vol. 293.","apa":"Edelsbrunner, H., &#38; Pach, J. (2024). Maximum Betti numbers of Čech complexes. In <i>40th International Symposium on Computational Geometry</i> (Vol. 293). Athens, Greece: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.53\">https://doi.org/10.4230/LIPIcs.SoCG.2024.53</a>","ama":"Edelsbrunner H, Pach J. Maximum Betti numbers of Čech complexes. In: <i>40th International Symposium on Computational Geometry</i>. Vol 293. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2024. doi:<a href=\"https://doi.org/10.4230/LIPIcs.SoCG.2024.53\">10.4230/LIPIcs.SoCG.2024.53</a>"},"acknowledgement":"The first author is supported by the European Research Council (ERC), grant no. 788183, and by the DFG Collaborative Research Center TRR 109, Austrian Science Fund (FWF), grant no. {I 02979-N35.} The second author is supported by the European Research Council (ERC), grant \"GeoScape\" and by the Hungarian Science Foundation (NKFIH), grant K-131529. Both authors are supported by the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31.\r\nThe authors thank Matt Kahle for communicating the question about extremal Čech complexes, Ben Schweinhart for early discussions on the linked circles construction in three dimensions, and Gábor Tardos for helpful remarks and suggestions.","external_id":{"arxiv":["2310.14801"]},"ddc":["510"],"author":[{"orcid":"0000-0002-9823-6833","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert","first_name":"Herbert","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87"},{"id":"E62E3130-B088-11EA-B919-BF823C25FEA4","full_name":"Pach, János","first_name":"János","last_name":"Pach"}],"quality_controlled":"1","project":[{"_id":"266A2E9E-B435-11E9-9278-68D0E5697425","grant_number":"788183","call_identifier":"H2020","name":"Alpha Shape Theory Extended"},{"grant_number":"I02979-N35","call_identifier":"FWF","name":"Persistence and stability of geometric complexes","_id":"2561EBF4-B435-11E9-9278-68D0E5697425"},{"grant_number":"Z00342","call_identifier":"FWF","name":"Mathematics, Computer Science","_id":"268116B8-B435-11E9-9278-68D0E5697425"}],"doi":"10.4230/LIPIcs.SoCG.2024.53","_id":"17146"},{"oa_version":"Submitted Version","OA_type":"green","publication_identifier":{"isbn":["9798350344851"],"issn":["1520-6149"]},"OA_place":"repository","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","status":"public","year":"2024","acknowledged_ssus":[{"_id":"ScienComp"}],"publisher":"IEEE","date_updated":"2025-11-05T07:21:31Z","publication_status":"published","month":"04","date_published":"2024-04-19T00:00:00Z","article_processing_charge":"No","department":[{"_id":"MaMo"},{"_id":"MaRo"}],"conference":{"end_date":"2024-04-19","location":"Seoul, Korea","start_date":"2024-04-14","name":"ICASSP: International Conference on Acoustics, Speech and Signal Processing"},"oa":1,"external_id":{"isi":["001396233806078"]},"citation":{"ista":"Depope A, Mondelli M, Robinson MR. 2024. Inference of genetic effects via approximate message passing. 2024 IEEE International Conference on Acoustics, Speech, and Signal Processing. ICASSP: International Conference on Acoustics, Speech and Signal Processing, 13151–13155.","chicago":"Depope, Al, Marco Mondelli, and Matthew Richard Robinson. “Inference of Genetic Effects via Approximate Message Passing.” In <i>2024 IEEE International Conference on Acoustics, Speech, and Signal Processing</i>, 13151–55. IEEE, 2024. <a href=\"https://doi.org/10.1109/ICASSP48485.2024.10447198\">https://doi.org/10.1109/ICASSP48485.2024.10447198</a>.","short":"A. Depope, M. Mondelli, M.R. Robinson, in:, 2024 IEEE International Conference on Acoustics, Speech, and Signal Processing, IEEE, 2024, pp. 13151–13155.","mla":"Depope, Al, et al. “Inference of Genetic Effects via Approximate Message Passing.” <i>2024 IEEE International Conference on Acoustics, Speech, and Signal Processing</i>, IEEE, 2024, pp. 13151–55, doi:<a href=\"https://doi.org/10.1109/ICASSP48485.2024.10447198\">10.1109/ICASSP48485.2024.10447198</a>.","ieee":"A. Depope, M. Mondelli, and M. R. Robinson, “Inference of genetic effects via approximate message passing,” in <i>2024 IEEE International Conference on Acoustics, Speech, and Signal Processing</i>, Seoul, Korea, 2024, pp. 13151–13155.","apa":"Depope, A., Mondelli, M., &#38; Robinson, M. R. (2024). Inference of genetic effects via approximate message passing. In <i>2024 IEEE International Conference on Acoustics, Speech, and Signal Processing</i> (pp. 13151–13155). Seoul, Korea: IEEE. <a href=\"https://doi.org/10.1109/ICASSP48485.2024.10447198\">https://doi.org/10.1109/ICASSP48485.2024.10447198</a>","ama":"Depope A, Mondelli M, Robinson MR. Inference of genetic effects via approximate message passing. In: <i>2024 IEEE International Conference on Acoustics, Speech, and Signal Processing</i>. IEEE; 2024:13151-13155. doi:<a href=\"https://doi.org/10.1109/ICASSP48485.2024.10447198\">10.1109/ICASSP48485.2024.10447198</a>"},"acknowledgement":"This work was supported by a Lopez-Loreta Prize to MM, an SNSF Eccellenza Grant to MRR (PCEGP3-181181), and core funding from ISTA. The authors thank Philip Schniter, Matthew Stephens and Pragya Sur for valuable suggestions on an early version of the work. The authors acknowledge the participants and investigators of the UK Biobank study. High-performance\r\ncomputing was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp).","publication":"2024 IEEE International Conference on Acoustics, Speech, and Signal Processing","type":"conference","_id":"17147","doi":"10.1109/ICASSP48485.2024.10447198","project":[{"name":"Prix Lopez-Loretta 2019 - Marco Mondelli","_id":"059876FA-7A3F-11EA-A408-12923DDC885E"},{"_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A","grant_number":"PCEGP3_181181","name":"Improving estimation and prediction of common complex disease risk"}],"quality_controlled":"1","page":"13151-13155","author":[{"first_name":"Al","full_name":"Depope, Al","id":"0b77531d-dbcd-11ea-9d1d-a8eee0bf3830","last_name":"Depope"},{"orcid":"0000-0002-3242-7020","last_name":"Mondelli","full_name":"Mondelli, Marco","first_name":"Marco","id":"27EB676C-8706-11E9-9510-7717E6697425"},{"id":"E5D42276-F5DA-11E9-8E24-6303E6697425","first_name":"Matthew Richard","full_name":"Robinson, Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813"}],"scopus_import":"1","isi":1,"date_created":"2024-06-16T22:01:07Z","abstract":[{"text":"Efficient utilization of large-scale biobank data is crucial for inferring the genetic basis of disease and predicting health outcomes from the DNA. Yet we lack efficient, accurate methods that scale to data where electronic health records are linked to whole genome sequence information. To address this issue, our paper develops a new algorithmic paradigm based on Approximate Message Passing (AMP), which is specifically tailored for genomic prediction and association testing. Our method yields comparable out-of-sample prediction accuracy to the state of the art on UK Biobank traits, whilst dramatically improving computational complexity, with a 8x-speed up in the run time. In addition, AMP theory provides a joint association testing framework, which outperforms the currently used REGENIE method, in roughly a third of the compute time. This first, truly large-scale application of the AMP framework lays the foundations for a far wider range of statistical analyses for hundreds of millions of variables measured on millions of people.","lang":"eng"}],"day":"19","language":[{"iso":"eng"}],"main_file_link":[{"open_access":"1","url":"https://openreview.net/forum?id=aQYCDxfZV0"}],"title":"Inference of genetic effects via approximate message passing"},{"related_material":{"record":[{"status":"public","relation":"dissertation_contains","id":"17164"}]},"language":[{"iso":"eng"}],"title":"Fluctuation moments for regular functions of Wigner Matrices","volume":27,"file_date_updated":"2024-06-26T11:26:42Z","date_created":"2024-06-21T09:31:17Z","day":"20","abstract":[{"lang":"eng","text":"We compute the deterministic approximation for mixed fluctuation moments of products of deterministic matrices and general Sobolev functions of Wigner matrices. Restricting to polynomials, our formulas reproduce recent results of Male et al. (Random Matrices Theory Appl. 11(2):2250015, 2022), showing that the underlying combinatorics of non-crossing partitions and annular non-crossing permutations continue to stay valid beyond the setting of second-order free probability theory. The formulas obtained further characterize the variance in the functional central limit theorem given in the recent companion paper (Reker in Preprint, arXiv:2204.03419, 2023). and thus allow identifying the fluctuation around the thermal value in certain thermalization problems."}],"scopus_import":"1","isi":1,"quality_controlled":"1","author":[{"last_name":"Reker","id":"e796e4f9-dc8d-11ea-abe3-97e26a0323e9","full_name":"Reker, Jana","first_name":"Jana"}],"_id":"17154","doi":"10.1007/s11040-024-09483-y","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331","call_identifier":"H2020","_id":"62796744-2b32-11ec-9570-940b20777f1d"}],"publication":"Mathematical Physics, Analysis and Geometry","type":"journal_article","external_id":{"isi":["001251464300001"],"arxiv":["2307.11029"]},"ddc":["519"],"citation":{"short":"J. Reker, Mathematical Physics, Analysis and Geometry 27 (2024).","chicago":"Reker, Jana. “Fluctuation Moments for Regular Functions of Wigner Matrices.” <i>Mathematical Physics, Analysis and Geometry</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s11040-024-09483-y\">https://doi.org/10.1007/s11040-024-09483-y</a>.","ista":"Reker J. 2024. Fluctuation moments for regular functions of Wigner Matrices. Mathematical Physics, Analysis and Geometry. 27(3), 10.","ama":"Reker J. Fluctuation moments for regular functions of Wigner Matrices. <i>Mathematical Physics, Analysis and Geometry</i>. 2024;27(3). doi:<a href=\"https://doi.org/10.1007/s11040-024-09483-y\">10.1007/s11040-024-09483-y</a>","apa":"Reker, J. (2024). Fluctuation moments for regular functions of Wigner Matrices. <i>Mathematical Physics, Analysis and Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11040-024-09483-y\">https://doi.org/10.1007/s11040-024-09483-y</a>","ieee":"J. Reker, “Fluctuation moments for regular functions of Wigner Matrices,” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 27, no. 3. Springer Nature, 2024.","mla":"Reker, Jana. “Fluctuation Moments for Regular Functions of Wigner Matrices.” <i>Mathematical Physics, Analysis and Geometry</i>, vol. 27, no. 3, 10, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s11040-024-09483-y\">10.1007/s11040-024-09483-y</a>."},"intvolume":"        27","arxiv":1,"oa":1,"article_processing_charge":"Yes (via OA deal)","article_number":"10","department":[{"_id":"LaEr"}],"publication_status":"published","date_updated":"2026-04-07T13:02:12Z","article_type":"original","date_published":"2024-06-20T00:00:00Z","month":"06","publisher":"Springer Nature","ec_funded":1,"issue":"3","year":"2024","status":"public","has_accepted_license":"1","publication_identifier":{"issn":["1385-0172"],"eissn":["1572-9656"]},"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","oa_version":"Published Version","file":[{"file_name":"2024_MathPhysAnaGeo_Reker.pdf","date_created":"2024-06-26T11:26:42Z","relation":"main_file","file_id":"17175","creator":"cchlebak","access_level":"open_access","content_type":"application/pdf","checksum":"7d04318d66f765621bdcb648378d458e","file_size":1327596,"success":1,"date_updated":"2024-06-26T11:26:42Z"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"}},{"publisher":"Institute of Science and Technology Austria","date_published":"2024-06-25T00:00:00Z","month":"06","publication_status":"published","date_updated":"2026-04-07T12:55:46Z","article_processing_charge":"No","department":[{"_id":"TaHa"},{"_id":"GradSch"}],"oa":1,"alternative_title":["ISTA Thesis"],"file":[{"relation":"source_file","date_created":"2024-06-26T20:56:27Z","file_name":"thesis.zip","file_id":"17179","checksum":"1610063569f5452f8a5acef728c2fc26","content_type":"application/zip","access_level":"closed","file_size":2761814,"creator":"krychlew","date_updated":"2024-06-26T21:00:14Z"},{"date_updated":"2024-06-26T20:58:24Z","content_type":"application/pdf","access_level":"open_access","checksum":"7bbadb1fbc9ed2a1ecf54597f88af99c","file_size":3695952,"creator":"krychlew","file_id":"17180","relation":"main_file","date_created":"2024-06-26T20:58:24Z","file_name":"thesis.pdf"}],"oa_version":"Published Version","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","short":"CC BY-NC-SA (4.0)","image":"/images/cc_by_nc_sa.png","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"OA_place":"publisher","publication_identifier":{"issn":["2663-337X"]},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","has_accepted_license":"1","corr_author":"1","degree_awarded":"PhD","year":"2024","status":"public","supervisor":[{"id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","full_name":"Hausel, Tamás","first_name":"Tamás","last_name":"Hausel","orcid":"0000-0002-9582-2634"}],"abstract":[{"lang":"eng","text":"This dissertation is the summary of the author’s work, concerning the relations between\r\ncohomology rings of algebraic varieties and rings of functions on zero schemes and fixed\r\npoint schemes. For most of the thesis, the focus is on smooth complex varieties with\r\nan action of a principally paired group, e.g. a parabolic subgroup of a reductive group.\r\nThe fundamental theorem 5.2.11 from co-authored article [66] says that if the principal\r\nnilpotent has a unique zero, then the zero scheme over the Kostant section is isomorphic\r\nto the spectrum of the equivariant cohomology ring, remembering the grading in terms of\r\na C^* action. A similar statement is proved also for the G-invariant functions on the total\r\nzero scheme over the whole Lie algebra. Additionally, we are able to prove an analogous\r\nresult for the GKM spaces, which poses the question on a joint generalisation.\r\nWe also tackle the situation of a singular variety. As long as it is embedded in a smooth\r\nvariety with regular action, we are able to study its cohomology as well by means of\r\nthe zero scheme. In case of e.g. Schubert varieties this determines the cohomology ring\r\ncompletely. In largest generality, this allows us to see a significant part of the cohomology\r\nring.\r\nWe also show (Theorem 6.2.1) that the cohomology ring of spherical varieties appears as\r\nthe ring of functions on the zero scheme. The computational aspect is not easy, but one\r\ncan hope that this can bring some concrete information about such cohomology rings.\r\nLastly, the K-theory conjecture 6.3.1 is studied, with some results attained for GKM\r\nspaces.\r\nThe thesis includes also an introduction to group actions on algebraic varieties. In\r\nparticular, the vector fields associated to the actions are extensively studied. We also\r\nprovide a version of the Kostant section for arbitrary principally paired group, which\r\nparametrises the regular orbits in the Lie algebra of an algebraic group. Before proving\r\nthe main theorem, we also include a historical overview of the field. In particular we bring\r\ntogether the results of Akyildiz, Carrell and Lieberman on non-equivariant cohomology\r\nrings."}],"day":"25","date_created":"2024-06-23T15:07:06Z","title":"Equivariant cohomology and rings of functions","language":[{"iso":"eng"}],"related_material":{"record":[{"id":"17157","relation":"part_of_dissertation","status":"public"}]},"file_date_updated":"2024-06-26T21:00:14Z","keyword":["equivariant cohomology","zero schemes","algebraic groups","Lie algebras"],"citation":{"ama":"Rychlewicz KP. Equivariant cohomology and rings of functions. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:17156\">10.15479/at:ista:17156</a>","apa":"Rychlewicz, K. P. (2024). <i>Equivariant cohomology and rings of functions</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:17156\">https://doi.org/10.15479/at:ista:17156</a>","ieee":"K. P. Rychlewicz, “Equivariant cohomology and rings of functions,” Institute of Science and Technology Austria, 2024.","mla":"Rychlewicz, Kamil P. <i>Equivariant Cohomology and Rings of Functions</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:17156\">10.15479/at:ista:17156</a>.","short":"K.P. Rychlewicz, Equivariant Cohomology and Rings of Functions, Institute of Science and Technology Austria, 2024.","chicago":"Rychlewicz, Kamil P. “Equivariant Cohomology and Rings of Functions.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:17156\">https://doi.org/10.15479/at:ista:17156</a>.","ista":"Rychlewicz KP. 2024. Equivariant cohomology and rings of functions. Institute of Science and Technology Austria."},"ddc":["516"],"type":"dissertation","doi":"10.15479/at:ista:17156","_id":"17156","project":[{"_id":"34cd0f74-11ca-11ed-8bc3-bf0492a14a24","name":"Topology of open smooth varieties with a torus action","grant_number":"26525"}],"page":"117","author":[{"last_name":"Rychlewicz","id":"85A07246-A8BF-11E9-B4FA-D9E3E5697425","first_name":"Kamil P","full_name":"Rychlewicz, Kamil P"}]}]