[{"day":"09","arxiv":1,"citation":{"mla":"Castellano, M., et al. “Investigating Ionising Sources and the Complex Interstellar Medium of GHZ2 at Z=12.3.” <i>The Open Journal of Astrophysics</i>, vol. 9, Maynooth Academic Publishing, 2026, doi:<a href=\"https://doi.org/10.33232/001c.160281\">10.33232/001c.160281</a>.","short":"M. Castellano, L. Napolitano, B. Moreschini, A. Calabrò, L. Christensen, M. Llerena, T.J.L.C. Bakx, F. Belfiore, D. Bevacqua, M. Dickinson, A. Fontana, G. Gandolfi, T. Gasparetto, A. Marconi, S. Mascia, E. Merlin, T. Morishita, T. Nanayakkara, D. Paris, L. Pentericci, B. Pérez-Díaz, G. Roberts-Borsani, S. Rojas-Ruiz, P. Santini, T. Treu, E. Vanzella, B. Vulcani, X. Wang, I. Yoon, J. Zavala, The Open Journal of Astrophysics 9 (2026).","chicago":"Castellano, M., L. Napolitano, B. Moreschini, A. Calabrò, L. Christensen, M. Llerena, T. J.L.C. Bakx, et al. “Investigating Ionising Sources and the Complex Interstellar Medium of GHZ2 at Z=12.3.” <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing, 2026. <a href=\"https://doi.org/10.33232/001c.160281\">https://doi.org/10.33232/001c.160281</a>.","apa":"Castellano, M., Napolitano, L., Moreschini, B., Calabrò, A., Christensen, L., Llerena, M., … Zavala, J. (2026). Investigating ionising sources and the complex interstellar medium of GHZ2 at z=12.3. <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing. <a href=\"https://doi.org/10.33232/001c.160281\">https://doi.org/10.33232/001c.160281</a>","ieee":"M. Castellano <i>et al.</i>, “Investigating ionising sources and the complex interstellar medium of GHZ2 at z=12.3,” <i>The Open Journal of Astrophysics</i>, vol. 9. Maynooth Academic Publishing, 2026.","ista":"Castellano M, Napolitano L, Moreschini B, Calabrò A, Christensen L, Llerena M, Bakx TJLC, Belfiore F, Bevacqua D, Dickinson M, Fontana A, Gandolfi G, Gasparetto T, Marconi A, Mascia S, Merlin E, Morishita T, Nanayakkara T, Paris D, Pentericci L, Pérez-Díaz B, Roberts-Borsani G, Rojas-Ruiz S, Santini P, Treu T, Vanzella E, Vulcani B, Wang X, Yoon I, Zavala J. 2026. Investigating ionising sources and the complex interstellar medium of GHZ2 at z=12.3. The Open Journal of Astrophysics. 9.","ama":"Castellano M, Napolitano L, Moreschini B, et al. Investigating ionising sources and the complex interstellar medium of GHZ2 at z=12.3. <i>The Open Journal of Astrophysics</i>. 2026;9. doi:<a href=\"https://doi.org/10.33232/001c.160281\">10.33232/001c.160281</a>"},"year":"2026","acknowledgement":"We thank the referee for the constructive comments that\r\nhelped us improve the manuscript. We thank S. Finkelstein,\r\nY. Harikane, C. Mason, and D. Stark for the useful comments.\r\nWe thank Tony Roman (Program Coordinator) and Glenn\r\nWahlgren (NIRSpec reviewer) for the assistance in the\r\npreparation of GO-3073 observations. This work is based\r\non observations made with the NASA/ESA/CSA James\r\nWebb Space Telescope (JWST). The JWST data presented in this article were obtained from the Mikulski Archive for\r\nSpace Telescopes (MAST) at the Space Telescope Science\r\nInstitute. The specific observations analysed are associated with program JWST-GO-3073 and can be accessed\r\nvia https://doi.org/10.17909/4r6b-bx96 (first pointing) and\r\nhttps://doi:10.17909/zq4g-r525 (second pointing). We\r\nacknowledge financial support from NASA through grant\r\nJWST-ERS-1324 and JWST-GO-3073. Support was also\r\nprovided by the PRIN 2022 MUR project 2022CB3PJ3 –\r\nFirst Light And Galaxy aSsembly (FLAGS) funded by the\r\nEuropean Union – Next Generation EU, by INAF GO Grant\r\n2024 ”Revealing the nature of bright galaxies at cosmic\r\ndawn with deep JWST spectroscopy”, by INAF Mini-grant\r\n2022 “Reionization and Fundamental Cosmology with\r\nHigh-Redshift Galaxies”, and by INAF Large Grant 2022\r\n“Extragalactic Surveys with JWST”. L.N. acknowledges\r\nsupport from grant “Progetti per Avvio alla Ricerca - Tipo\r\n1, Unveiling Cosmic Dawn: Galaxy Evolution with CAPERS” (AR1241906F947685). EV acknowledges financial\r\nsupport through grants INAF GO Grant 2024 “Mapping Star\r\nCluster Feedback in a Galaxy 450 Myr after the Big Bang”\r\nand by the European Union – NextGenerationEU within\r\nPRIN 2022 project n.20229YBSAN - Globular clusters\r\nin cosmological simulations and lensed fields: from their\r\nbirth to the present epoch. AM acknowledges support\r\nfrom project PRIN-MUR project “PROMETEUS” financed\r\nby the European Union - Next Generation EU, Mission 4\r\nComponent 1 CUP B53D2300475000. AM acknowledges\r\nsupport from Ricerca Fondamentale INAF under Mini Grant\r\n2023 ”Quantitative Spectroscopy of Ionized Nebulae and\r\nGalaxies (QSING)” and under Data Analysis Grant 2024\r\n“Accurate measurements of metallicity in galaxies with a new\r\napproach to photoionization modelling”.","publisher":"Maynooth Academic Publishing","status":"public","_id":"21934","oa_version":"Published Version","external_id":{"arxiv":["2512.08490"]},"file":[{"access_level":"open_access","checksum":"ec33ca56b8836c61cb01e26893d43cbf","relation":"main_file","creator":"dernst","date_updated":"2026-06-02T06:38:59Z","content_type":"application/pdf","success":1,"file_id":"21935","date_created":"2026-06-02T06:38:59Z","file_size":4855934,"file_name":"2026_OpenJourAstrophysics_Castellano.pdf"}],"intvolume":"         9","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-06-02T06:38:59Z","abstract":[{"text":"An accurate characterisation of the physical properties of galaxies at cosmic dawn is key to understanding\r\nthe origin of the high abundance of UV-bright galaxies at z≳10. We exploit deep (9.1-hour exposure time)\r\nNIRSpec PRISM observations of GHZ2 to constrain the sources of ionising radiation and the properties of the\r\ninterstellar medium (ISM) in this bright, compact, and highly ionising galaxy at z=12.3. We measure with\r\nhigh significance the prominent N IV, C IV, He II, O III, C III, O II, and Ne III emission features previously\r\ndetected in shallower observations, and confirm the detection of the N III] λ1750 multiplet, yielding tight\r\nconstraints on the N/O ratio, which is found to be ≃2 times the solar value. We also detect the Mg II λ2800,\r\n[Fe IV] λ2833 and Si II λ1812 doublets, the H8+HeI λλ3889 blend, and the Si IV+O IV] λλ1400 absorption\r\ncomplex. The O III λ3133 fluorescence line is only detected in the first observing epoch, implying variability\r\non a rest-frame time span of 19 days, strongly suggesting the presence of an active nucleus. Combining the\r\nNIRSpec dataset with available optical and far-infrared constraints from MIRI and ALMA, we show that the\r\nemission spectrum of GHZ2 cannot be reproduced by single-density spectro-photometric models, even under\r\nextreme assumptions on the ionisation parameter and electron density. Multi-zone photoionisation modelling\r\nperformed with the HOMERUN code demonstrates that star formation must be occurring in a strongly stratified\r\nISM, where both low-/intermediate-density gas and high-density regions (log(ne/cm−3\r\n) ≳ 4) coexist. The\r\nGHZ2 emission landscape is consistent with either a composite star-formation plus AGN scenario, or with\r\nstar formation occurring in a combination of radiation- and matter-bounded regions. Purely radiation-bounded\r\nstellar models fail to reproduce the observed He II emission, making an additional hard ionising component\r\nunavoidable.","lang":"eng"}],"date_updated":"2026-06-02T06:39:53Z","OA_place":"publisher","DOAJ_listed":"1","ddc":["520"],"date_published":"2026-04-09T00:00:00Z","OA_type":"diamond","has_accepted_license":"1","PlanS_conform":"1","fulldoi":"https://doi.org/10.33232/001c.160281","article_type":"original","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"month":"04","department":[{"_id":"JoMa"}],"volume":9,"language":[{"iso":"eng"}],"publication_status":"published","quality_controlled":"1","date_created":"2026-05-31T22:02:14Z","article_processing_charge":"No","publication":"The Open Journal of Astrophysics","author":[{"first_name":"M.","full_name":"Castellano, M.","last_name":"Castellano"},{"first_name":"L.","last_name":"Napolitano","full_name":"Napolitano, L."},{"full_name":"Moreschini, B.","last_name":"Moreschini","first_name":"B."},{"full_name":"Calabrò, A.","last_name":"Calabrò","first_name":"A."},{"last_name":"Christensen","full_name":"Christensen, L.","first_name":"L."},{"first_name":"M.","full_name":"Llerena, M.","last_name":"Llerena"},{"full_name":"Bakx, T. J.L.C.","last_name":"Bakx","first_name":"T. J.L.C."},{"full_name":"Belfiore, F.","last_name":"Belfiore","first_name":"F."},{"first_name":"D.","full_name":"Bevacqua, D.","last_name":"Bevacqua"},{"first_name":"M.","last_name":"Dickinson","full_name":"Dickinson, M."},{"full_name":"Fontana, A.","last_name":"Fontana","first_name":"A."},{"first_name":"G.","last_name":"Gandolfi","full_name":"Gandolfi, G."},{"first_name":"T.","last_name":"Gasparetto","full_name":"Gasparetto, T."},{"first_name":"A.","full_name":"Marconi, A.","last_name":"Marconi"},{"first_name":"Sara","id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","last_name":"Mascia","full_name":"Mascia, Sara"},{"first_name":"E.","full_name":"Merlin, E.","last_name":"Merlin"},{"first_name":"T.","full_name":"Morishita, T.","last_name":"Morishita"},{"last_name":"Nanayakkara","full_name":"Nanayakkara, T.","first_name":"T."},{"full_name":"Paris, D.","last_name":"Paris","first_name":"D."},{"first_name":"L.","last_name":"Pentericci","full_name":"Pentericci, L."},{"full_name":"Pérez-Díaz, B.","last_name":"Pérez-Díaz","first_name":"B."},{"last_name":"Roberts-Borsani","full_name":"Roberts-Borsani, G.","first_name":"G."},{"first_name":"S.","full_name":"Rojas-Ruiz, S.","last_name":"Rojas-Ruiz"},{"full_name":"Santini, P.","last_name":"Santini","first_name":"P."},{"first_name":"T.","last_name":"Treu","full_name":"Treu, T."},{"last_name":"Vanzella","full_name":"Vanzella, E.","first_name":"E."},{"full_name":"Vulcani, B.","last_name":"Vulcani","first_name":"B."},{"first_name":"X.","full_name":"Wang, X.","last_name":"Wang"},{"first_name":"I.","full_name":"Yoon, I.","last_name":"Yoon"},{"last_name":"Zavala","full_name":"Zavala, J.","first_name":"J."}],"scopus_import":"1","publication_identifier":{"eissn":["2565-6120"]},"oa":1,"title":"Investigating ionising sources and the complex interstellar medium of GHZ2 at z=12.3","doi":"10.33232/001c.160281","type":"journal_article"},{"quality_controlled":"1","related_material":{"link":[{"relation":"software","url":"https://github.com/tamirshor7/T1-PILOT"}]},"article_processing_charge":"No","date_created":"2026-06-07T22:01:36Z","month":"03","page":"1969-1982","publication_status":"accepted","volume":315,"department":[{"_id":"AlBr"}],"language":[{"iso":"eng"}],"title":"T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration","oa":1,"publication_identifier":{"eissn":["2640-3498"]},"type":"conference","main_file_link":[{"url":"https://openreview.net/forum?id=nZaPtHbd6N#discussion","open_access":"1"}],"publication":"Medical Imaging with Deep Learning","author":[{"first_name":"Tamir","full_name":"Shor, Tamir","last_name":"Shor"},{"full_name":"Freiman, Moti","last_name":"Freiman","first_name":"Moti"},{"first_name":"Chaim","last_name":"Baskin","full_name":"Baskin, Chaim"},{"last_name":"Bronstein","id":"58f3726e-7cba-11ef-ad8b-e6e8cb3904e6","full_name":"Bronstein, Alexander","first_name":"Alexander","orcid":"0000-0001-9699-8730"}],"conference":{"location":"Taipei, Taiwan","end_date":"2026-07-10","name":"MIDL: Medical Imaging with Deep Learning","start_date":"2026-07-08"},"corr_author":"1","scopus_import":"1","intvolume":"       315","day":"17","publisher":"ML Research Press","citation":{"ista":"Shor T, Freiman M, Baskin C, Bronstein AM. T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. Medical Imaging with Deep Learning. MIDL: Medical Imaging with Deep Learning, PMLR, vol. 315, 1969–1982.","ama":"Shor T, Freiman M, Baskin C, Bronstein AM. T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. In: <i>Medical Imaging with Deep Learning</i>. Vol 315. ML Research Press; :1969-1982.","ieee":"T. Shor, M. Freiman, C. Baskin, and A. M. Bronstein, “T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration,” in <i>Medical Imaging with Deep Learning</i>, Taipei, Taiwan, vol. 315, pp. 1969–1982.","apa":"Shor, T., Freiman, M., Baskin, C., &#38; Bronstein, A. M. (n.d.). T1-PILOT: Physics-informed learned optimized trajectories for T1 mapping acceleration. In <i>Medical Imaging with Deep Learning</i> (Vol. 315, pp. 1969–1982). Taipei, Taiwan: ML Research Press.","chicago":"Shor, Tamir, Moti Freiman, Chaim Baskin, and Alex M. Bronstein. “T1-PILOT: Physics-Informed Learned Optimized Trajectories for T1 Mapping Acceleration.” In <i>Medical Imaging with Deep Learning</i>, 315:1969–82. ML Research Press, n.d.","mla":"Shor, Tamir, et al. “T1-PILOT: Physics-Informed Learned Optimized Trajectories for T1 Mapping Acceleration.” <i>Medical Imaging with Deep Learning</i>, vol. 315, ML Research Press, pp. 1969–82.","short":"T. Shor, M. Freiman, C. Baskin, A.M. Bronstein, in:, Medical Imaging with Deep Learning, ML Research Press, n.d., pp. 1969–1982."},"year":"2026","status":"public","_id":"21949","oa_version":"Published Version","OA_place":"publisher","has_accepted_license":"1","date_published":"2026-03-17T00:00:00Z","OA_type":"gold","ddc":["000"],"keyword":["Cardiac T1 Mapping","Trajectory Optimization and Reconstruction","PhysicsInformed Deep-Learning"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema.\r\nHowever, the inherently dynamic nature of the heart imposes strict limits on acquisition\r\ntimes, making high-resolution T1 mapping a persistent challenge. Compressed sensing (CS)\r\napproaches have reduced scan durations by undersampling k-space and reconstructing images from partial data, and recent studies show that jointly optimizing the undersampling\r\npatterns with the reconstruction network can substantially improve performance. Still,\r\nmost current T1 mapping pipelines rely on static, hand-crafted masks that do not exploit\r\nthe full acceleration and accuracy potential. Furthermore, most existing methods do not\r\nlevarage the physical T1 decay model in optimization. In this work, we introduce T1-\r\nPILOT: an end-to-end method that explicitly incorporates the T1 signal relaxation model\r\ninto the sampling–reconstruction framework to guide the learning of non-Cartesian trajectories, cross-frame alignment, and T1 decay estimation. Through extensive experiments\r\non the CMRxRecon dataset, T1-PILOT significantly outperforms several baseline strategies (including learned single-mask and fixed radial or golden-angle sampling schemes),\r\nachieving higher T1 map fidelity at greater acceleration factors. In particular, we observe consistent gains in PSNR and VIF relative to existing methods, along with marked\r\nimprovements in delineating finer myocardial structures. Our results highlight that optimizing sampling trajectories in tandem with the physical relaxation model leads to both\r\nenhanced quantitative accuracy and reduced acquisition times. Code for reproducing all\r\nexperiments and results is available at https://github.com/tamirshor7/T1-PILOT","lang":"eng"}],"alternative_title":["PMLR"],"date_updated":"2026-06-08T08:05:24Z"},{"has_accepted_license":"1","PlanS_conform":"1","OA_type":"diamond","date_published":"2026-05-25T00:00:00Z","ddc":["520"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"fulldoi":"https://doi.org/10.33232/001c.162505","article_type":"original","DOAJ_listed":"1","OA_place":"publisher","date_updated":"2026-06-08T08:25:40Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","file_date_updated":"2026-06-08T08:23:37Z","abstract":[{"lang":"eng","text":"The central engines of Little Red Dots (LRDs) may be “black hole stars” (BH*s), early stages of\r\nblack hole growth characterized by dense gas envelopes. So far, the most direct evidence for BH*s\r\ncomes from a handful of sources where the host galaxy is completely outshone as suggested by their\r\nremarkably steep Balmer breaks. Here we present a novel scheme to disentangle BH*s from their\r\nhost galaxies assuming that the [O III]5008˚A line arises exclusively from the host. Using a sample\r\nof 98 LRDs (z ≈ 2 − 9) with high quality NIRSpec/PRISM spectra, we demonstrate that the hostsubtracted median stack displays a Balmer break > 2× stronger than massive quiescent galaxies,\r\nwith the rest-optical continuum resembling a blackbody-like SED (Teff ≈ 4050 K, log(Lbol) ≈ 43.9\r\nerg s−1\r\n, Reff ≈ 1300 au). We measure a steep Balmer decrement (Hα/Hβ > 10) and numerous\r\ndensity-sensitive features (e.g., Fe II, He I, O I). These are hallmark signatures of dense gas envelopes,\r\nproviding population-level evidence that BH*s indeed power LRDs. In the median LRD, BH*s account\r\nfor ∼ 20% of the UV emission, ∼ 50% at the Balmer break, and ∼ 90% at wavelengths longer\r\nthan Hα with the remainder arising from the host. BH*s preferentially reside in low-mass galaxies\r\n(M⋆ ≈ 108 M⊙) undergoing recent starbursts, as evidenced by extreme emission line EWs (e.g.,\r\n[O III]5008˚A≈ 1100˚A, C III]≈ 12˚A), thereby favoring BH* origins linked to star-formation. We show\r\nV-shaped LRD selections are biased to high BH*/host fractions (≳ 60% at 5500˚A) – less dominant\r\nBH*s may be powering JWST’s blue broad-line AGN. We find BH*s are so commonplace and transient\r\n(duty cycle ∼ 1%, lifetime ∼ 10 Myrs) that every massive black hole may have once shone as a BH*.\r\n"}],"external_id":{"arxiv":["2601.20929"]},"intvolume":"         9","file":[{"access_level":"open_access","checksum":"33c4a444f7c37b3f47ecbd53eb187c1b","relation":"main_file","content_type":"application/pdf","date_updated":"2026-06-08T08:23:37Z","creator":"dernst","success":1,"file_id":"21952","file_name":"2026_OpenJourAstrophysics_Sun.pdf","file_size":7591188,"date_created":"2026-06-08T08:23:37Z"}],"status":"public","_id":"21951","oa_version":"Published Version","arxiv":1,"day":"25","publisher":"Maynooth Academic Publishing","citation":{"ista":"Sun WQ, Naidu RP, Matthee JJ, De Graaff A, Chisholm J, Greene JE, Oesch PA, Torralba Torregrosa A, Hviding RE, Brammer G, Simcoe RA, Bose S, Bouwens R, Dayal P, Eilers AC, Fei Q, Furtak LJ, Gottumukkala R, Goulding A, Heintz KE, Hirschmann M, Kokorev V, Leja J, Liu Z, Natarajan P, Santarelli AD, Setton DJ, Smith A, Tacchella S, Volonteri M, Walter F, Weibel A, Williams CC. 2026. Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. The Open Journal of Astrophysics. 9.","ama":"Sun WQ, Naidu RP, Matthee JJ, et al. Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. <i>The Open Journal of Astrophysics</i>. 2026;9. doi:<a href=\"https://doi.org/10.33232/001c.162505\">10.33232/001c.162505</a>","apa":"Sun, W. Q., Naidu, R. P., Matthee, J. J., De Graaff, A., Chisholm, J., Greene, J. E., … Williams, C. C. (2026). Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot. <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing. <a href=\"https://doi.org/10.33232/001c.162505\">https://doi.org/10.33232/001c.162505</a>","ieee":"W. Q. Sun <i>et al.</i>, “Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot,” <i>The Open Journal of Astrophysics</i>, vol. 9. Maynooth Academic Publishing, 2026.","chicago":"Sun, Wendy Q., Rohan P. Naidu, Jorryt J Matthee, Anna De Graaff, John Chisholm, Jenny E. Greene, Pascal A. Oesch, et al. “Little Red Dot - Host Galaxy = Black Hole Star: A Gas-Enshrouded Heart at the Center of Every Little Red Dot.” <i>The Open Journal of Astrophysics</i>. Maynooth Academic Publishing, 2026. <a href=\"https://doi.org/10.33232/001c.162505\">https://doi.org/10.33232/001c.162505</a>.","mla":"Sun, Wendy Q., et al. “Little Red Dot - Host Galaxy = Black Hole Star: A Gas-Enshrouded Heart at the Center of Every Little Red Dot.” <i>The Open Journal of Astrophysics</i>, vol. 9, Maynooth Academic Publishing, 2026, doi:<a href=\"https://doi.org/10.33232/001c.162505\">10.33232/001c.162505</a>.","short":"W.Q. Sun, R.P. Naidu, J.J. Matthee, A. De Graaff, J. Chisholm, J.E. Greene, P.A. Oesch, A. Torralba Torregrosa, R.E. Hviding, G. Brammer, R.A. Simcoe, S. Bose, R. Bouwens, P. Dayal, A.C. Eilers, Q. Fei, L.J. Furtak, R. Gottumukkala, A. Goulding, K.E. Heintz, M. Hirschmann, V. Kokorev, J. Leja, Z. Liu, P. Natarajan, A.D. Santarelli, D.J. Setton, A. Smith, S. Tacchella, M. Volonteri, F. Walter, A. Weibel, C.C. Williams, The Open Journal of Astrophysics 9 (2026)."},"year":"2026","acknowledgement":"We thank the two anonymous referees for their insightful comments that have strengthened this work.\r\nWQS and RPN acknowledge funding from JWST programs GO-3516, GO-5224, and the MIT Undergraduate\r\nResearch Opportunities Program (UROP). Support for\r\nthis work was provided by NASA through the NASA\r\nHubble Fellowship grant HST-HF2-51515.001-A awarded\r\nby the Space Telescope Science Institute, which is operated by the Association of Universities for Research in\r\nAstronomy, Incorporated, under NASA contract NAS5-\r\n26555. RPN thanks Neil Pappalardo and Jane Pappalardo for their generous support of the MIT Pappalardo Fellowships in Physics, and for their enthusiasm\r\nand encouragement for pursuing the earliest galaxies and\r\nblack holes. JM and AT acknowledge funding from the\r\nEuropean Union (ERC, AGENTS, 101076224). KEH\r\nacknowledges support from the Independent Research Fund Denmark (DFF) under grant 5251-00009B and cofunding by the European Union (ERC, HEAVYMETAL,\r\n101071865). Views and opinions expressed are, however,\r\nthose of the authors only and do not necessarily reflect\r\nthose of the European Union or the European Research\r\nCouncil. Neither the European Union nor the granting\r\nauthority can be held responsible for them. REH acknowledges support by the German Aerospace Center\r\n(DLR) and the Federal Ministry for Economic Affairs\r\nand Energy (BMWi) through program 50OR2403 ‘RUBIES’.\r\nThe data products presented herein were retrieved\r\nfrom the Dawn JWST Archive (DJA). DJA is an initiative of the Cosmic Dawn Center (DAWN), which is\r\nfunded by the Danish National Research Foundation under grant DNRF140. This work is based on observations\r\nmade with the NASA/ESA/CSA James Webb Space\r\nTelescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope\r\nScience Institute, which is operated by the Association\r\nof Universities for Research in Astronomy, Inc., under\r\nNASA contract NAS 5-03127 for JWST. Support for\r\nprograms #3516, #5224, #5664 was provided by NASA\r\nthrough grants from the Space Telescope Science Institute, which is operated by the Association of Universities\r\nfor Research in Astronomy, Inc., under NASA contract\r\nNAS 5-03127.\r\nThe spectra used in this paper are associated with programs 1180 (D’Eugenio et al. 2025d), 1181 (PI: D. Eisenstein), 1208 (Willott et al. 2022), 1210 (PI: N. Luetzgendorf), 1211 (Maseda et al. 2024), 1212 - 1215 (PI: N.\r\nLuetzgendorf), 1228 (Luhman et al. 2024b), 1229 (Luhman et al. 2024a), 1286 (PI: N. Luetzgendorf), 1287 (PI:\r\nK. Isaak), 1345 (Finkelstein et al. 2023), 1433 (Hsiao\r\net al. 2024), 1747 (PI: G. Roberts-Borsani), 2028 (Wang\r\net al. 2024c), 2073 (PI: J. Hennawi), 2198 (Barrufet\r\net al. 2025), 2282 (Bradley et al. 2023), 2561 (Bezanson\r\net al. 2024), 2565 (Nanayakkara et al. 2025), 2640 (PI:\r\nW. Best), 2750 (Arrabal Haro et al. 2023), 2756 (Mascia et al. 2024), 2767 (Williams et al. 2023b), 2770 (PI:\r\nM. McCaughrean), 3073 (Castellano et al. 2024), 3215\r\n(Eisenstein et al. 2025), 4106 (PI: E. Nelson), 4233 (de\r\nGraaff et al. 2025c), 4446 (Frye et al. 2024), 4557 (PI: H.\r\nYan), 5105 (Shen et al. 2024), 5224 (PIs: P.A. Oesch &\r\nR.P. Naidu), 6368 (PI: M. Dickinson), 6541 (DeCoursey\r\net al. 2025), 6585 (PI: D. Coulter), 6642 (PI: J. Muzerolle\r\nPage), and FRESCO IFU (Matthee et al. 2024; Torralba\r\net al. 2025b).\r\nSoftware used in developing this work includes:\r\nmatplotlib (Hunter 2007), jupyter (Kluyver et al.\r\n2016), IPython (P´erez & Granger 2007), numpy\r\n(Oliphant 2015), scipy (Virtanen et al. 2020), TOPCAT\r\n(Taylor 2005), Astropy (Astropy Collaboration et al.\r\n2013), msaexp (Brammer 2023).","title":"Little Red Dot - Host Galaxy = Black Hole Star: A gas-enshrouded heart at the center of every Little Red Dot","oa":1,"publication_identifier":{"eissn":["2565-6120"]},"type":"journal_article","doi":"10.33232/001c.162505","scopus_import":"1","publication":"The Open Journal of Astrophysics","author":[{"full_name":"Sun, Wendy Q.","last_name":"Sun","first_name":"Wendy Q."},{"first_name":"Rohan P.","last_name":"Naidu","full_name":"Naidu, Rohan P."},{"orcid":"0000-0003-2871-127X","first_name":"Jorryt J","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","last_name":"Matthee"},{"first_name":"Anna","full_name":"De Graaff, Anna","last_name":"De Graaff"},{"first_name":"John","full_name":"Chisholm, John","last_name":"Chisholm"},{"first_name":"Jenny E.","full_name":"Greene, Jenny E.","last_name":"Greene"},{"first_name":"Pascal A.","full_name":"Oesch, Pascal A.","last_name":"Oesch"},{"first_name":"Alberto","orcid":"0000-0001-5586-6950","full_name":"Torralba Torregrosa, Alberto","id":"018f0249-0e87-11f0-b167-cbce08fbd541","last_name":"Torralba Torregrosa"},{"first_name":"Raphael E.","full_name":"Hviding, Raphael E.","last_name":"Hviding"},{"last_name":"Brammer","full_name":"Brammer, Gabriel","first_name":"Gabriel"},{"first_name":"Robert A.","last_name":"Simcoe","full_name":"Simcoe, Robert A."},{"full_name":"Bose, Sownak","last_name":"Bose","first_name":"Sownak"},{"first_name":"Rychard","full_name":"Bouwens, Rychard","last_name":"Bouwens"},{"full_name":"Dayal, Pratika","last_name":"Dayal","first_name":"Pratika"},{"full_name":"Eilers, Anna Christina","last_name":"Eilers","first_name":"Anna Christina"},{"full_name":"Fei, Qinyue","last_name":"Fei","first_name":"Qinyue"},{"last_name":"Furtak","full_name":"Furtak, Lukas J.","first_name":"Lukas J."},{"full_name":"Gottumukkala, Rashmi","last_name":"Gottumukkala","first_name":"Rashmi"},{"last_name":"Goulding","full_name":"Goulding, Andy","first_name":"Andy"},{"first_name":"Kasper E.","last_name":"Heintz","full_name":"Heintz, Kasper E."},{"last_name":"Hirschmann","full_name":"Hirschmann, Michaela","first_name":"Michaela"},{"last_name":"Kokorev","full_name":"Kokorev, Vasily","first_name":"Vasily"},{"first_name":"Joel","full_name":"Leja, Joel","last_name":"Leja"},{"first_name":"Zhaoran","last_name":"Liu","full_name":"Liu, Zhaoran"},{"first_name":"Priyamvada","last_name":"Natarajan","full_name":"Natarajan, Priyamvada"},{"first_name":"Andrew D.","last_name":"Santarelli","full_name":"Santarelli, Andrew D."},{"first_name":"David J.","full_name":"Setton, David J.","last_name":"Setton"},{"full_name":"Smith, Aaron","last_name":"Smith","first_name":"Aaron"},{"first_name":"Sandro","full_name":"Tacchella, Sandro","last_name":"Tacchella"},{"full_name":"Volonteri, Marta","last_name":"Volonteri","first_name":"Marta"},{"first_name":"Fabian","full_name":"Walter, Fabian","last_name":"Walter"},{"full_name":"Weibel, Andrea","last_name":"Weibel","first_name":"Andrea"},{"first_name":"Christina C.","full_name":"Williams, Christina C.","last_name":"Williams"}],"article_processing_charge":"No","date_created":"2026-06-07T22:01:36Z","project":[{"_id":"bd9b2118-d553-11ed-ba76-db24564edfea","name":"Young galaxies as tracers and agents of cosmic reionization","grant_number":"101076224"}],"quality_controlled":"1","publication_status":"published","volume":9,"department":[{"_id":"JoMa"}],"language":[{"iso":"eng"}],"month":"05"},{"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","date_created":"2026-06-08T08:34:43Z","month":"05","publication_status":"published","language":[{"iso":"eng"}],"department":[{"_id":"UlWa"}],"volume":68,"article_number":"20","oa":1,"title":"Train-free segmentation in MRI with cubical persistent homology","publication_identifier":{"issn":["0924-9907"],"eissn":["1573-7683"]},"type":"journal_article","doi":"10.1007/s10851-026-01300-1","publication":"Journal of Mathematical Imaging and Vision","author":[{"full_name":"François, Anton","last_name":"François","first_name":"Anton"},{"orcid":"0000-0002-1404-1095","first_name":"Raphaël","full_name":"Tinarrage, Raphaël","id":"40ebcc9d-905f-11ef-bf0a-dc475da8a04e","last_name":"Tinarrage"}],"corr_author":"1","scopus_import":"1","issue":"3","external_id":{"arxiv":["2401.01160"]},"intvolume":"        68","file":[{"creator":"dernst","content_type":"application/pdf","date_updated":"2026-06-10T07:58:58Z","access_level":"open_access","checksum":"34080653e0f9c6160856a6bbca9b5248","relation":"main_file","file_size":6070434,"date_created":"2026-06-10T07:58:58Z","file_name":"2026_JourMathImaging_Francois.pdf","success":1,"file_id":"21990"}],"arxiv":1,"day":"25","publisher":"Springer Nature","citation":{"short":"A. François, R. Tinarrage, Journal of Mathematical Imaging and Vision 68 (2026).","mla":"François, Anton, and Raphaël Tinarrage. “Train-Free Segmentation in MRI with Cubical Persistent Homology.” <i>Journal of Mathematical Imaging and Vision</i>, vol. 68, no. 3, 20, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1007/s10851-026-01300-1\">10.1007/s10851-026-01300-1</a>.","chicago":"François, Anton, and Raphaël Tinarrage. “Train-Free Segmentation in MRI with Cubical Persistent Homology.” <i>Journal of Mathematical Imaging and Vision</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s10851-026-01300-1\">https://doi.org/10.1007/s10851-026-01300-1</a>.","apa":"François, A., &#38; Tinarrage, R. (2026). Train-free segmentation in MRI with cubical persistent homology. <i>Journal of Mathematical Imaging and Vision</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10851-026-01300-1\">https://doi.org/10.1007/s10851-026-01300-1</a>","ieee":"A. François and R. Tinarrage, “Train-free segmentation in MRI with cubical persistent homology,” <i>Journal of Mathematical Imaging and Vision</i>, vol. 68, no. 3. Springer Nature, 2026.","ama":"François A, Tinarrage R. Train-free segmentation in MRI with cubical persistent homology. <i>Journal of Mathematical Imaging and Vision</i>. 2026;68(3). doi:<a href=\"https://doi.org/10.1007/s10851-026-01300-1\">10.1007/s10851-026-01300-1</a>","ista":"François A, Tinarrage R. 2026. Train-free segmentation in MRI with cubical persistent homology. Journal of Mathematical Imaging and Vision. 68(3), 20."},"acknowledgement":"Open access funding provided by Institute of Science and Technology (IST Austria).","year":"2026","_id":"21954","status":"public","oa_version":"Published Version","OA_place":"publisher","date_published":"2026-05-25T00:00:00Z","PlanS_conform":"1","has_accepted_license":"1","OA_type":"hybrid","ddc":["510"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","fulldoi":"https://doi.org/10.1007/s10851-026-01300-1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"We investigate a framework for train-free MRI segmentation based on Topological Data Analysis. The pipeline proceeds in three steps, first identifying the whole object to segment via automatic thresholding, then detecting a distinctive subset whose topology is known in advance, and finally deducing the various components of the segmentation. A key ingredient is the extraction of approximate representative cycles from persistence diagrams, which provides an interpretable link between persistent features and anatomical components. To clarify the method’s scope, we make the underlying topological and intensity assumptions explicit, quantify when they hold on real data, and analyze typical failure modes. We evaluate the approach on glioblastoma and on fetal cortical plate segmentation, with comparisons to unsupervised and deep-learning references. By operating without large annotated datasets, the method is well suited to scarce-data settings and provides an interpretable baseline and practical initialization for expert refinement or learning-based pipelines.","lang":"eng"}],"file_date_updated":"2026-06-10T07:58:58Z","date_updated":"2026-06-10T08:00:52Z"},{"acknowledged_ssus":[{"_id":"PreCl"},{"_id":"LifeSc"},{"_id":"MassSpec"},{"_id":"Bio"}],"_id":"21962","status":"public","oa_version":"Preprint","day":"05","citation":{"apa":"Villalba Requena, A., Beattie, R. J., Pauler, F., Streicher, C., Miranda, O., Krausgruber, T., … Hippenmeyer, S. (n.d.). Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>","ieee":"A. Villalba Requena <i>et al.</i>, “Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner,” <i>bioRxiv</i>. .","ista":"Villalba Requena A, Beattie RJ, Pauler F, Streicher C, Miranda O, Krausgruber T, Senekowitsch M, Farlik M, Bock C, Rülicke T, Hippenmeyer S. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","ama":"Villalba Requena A, Beattie RJ, Pauler F, et al. Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>","mla":"Villalba Requena, Ana, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722172\">10.64898/2026.05.01.722172</a>.","short":"A. Villalba Requena, R.J. Beattie, F. Pauler, C. Streicher, O. Miranda, T. Krausgruber, M. Senekowitsch, M. Farlik, C. Bock, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","chicago":"Villalba Requena, Ana, Robert J Beattie, Florian Pauler, Carmen Streicher, Osvaldo Miranda, Thomas Krausgruber, Martin Senekowitsch, et al. “Mtor/Rptor Function Globally Prevents Cortical Microcephaly and Cell-Autonomously Promotes Postnatal Neuron Survival in Cell Type Specific Manner.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722172\">https://doi.org/10.64898/2026.05.01.722172</a>."},"acknowledgement":"We thank A. Heger (IST Austria Preclinical Facility), A. Sommer (VBCF GmbH, NGS Unit), and A.\r\nNicolas (IST Austria Lab Support Facility / Mass Spectrometry Facility) for technical support; K. Ferencak,\r\nI. Aykara, P. Hirschfeld, E. Fisher, S. Laukoter, L. Andersen for initial experiments and/or assistance; and\r\nall members of the Hippenmeyer lab for discussion. This research was supported by the Scientific Service\r\nUnits (SSU) of IST Austria through resources provided by the Imaging and Optics- (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). R.B. received support from FWF Meitner-Programm (M 2416). This\r\nwork was also supported by IST Austria institutional funds; the People Programme (Marie Curie Actions)\r\nof the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement\r\nNo 618444 to S.H., and the European Research Council (ERC) under the European Union’s Horizon 2020\r\nresearch and innovation programme (grant agreement No 725780 LinPro) to S.H.","year":"2026","OA_type":"green","has_accepted_license":"1","date_published":"2026-05-05T00:00:00Z","ddc":["570"],"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"fulldoi":"https://doi.org/10.64898/2026.05.01.722172","OA_place":"repository","date_updated":"2026-06-16T08:45:25Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"The generation of faithful cell-type diversity and correct projection neuron numbers is essential for cerebral cortex development. Corticogenesis is however susceptible to genetic interference of critical signaling pathways, including mutations in Mtor/Rptor that lead to microcephaly. How the loss of Rptor/mTORC1 function affects cortical developmental programs, at single cell level, is still unknown. Here, we utilized Mosaic Analysis with Double Markers (MADM) technology to probe Rptor gene function upon sparse single cell- or global tissue-wide ablation. We found that tissue-wide effects drive the etiology of cortical microcephaly upon loss of Rptor, rather than deficits in projection neuron genesis. Conversely, Rptor function is cell-autonomously required for postnatal projection neuron survival in a highly cell-type-specific manner. Collectively, our results suggest that the fine balance of precise cell-type-specific cell-autonomous Rptor/mTORC1 function in concert with non-cell-autonomous tissue-wide effects is essential for the development of a properly-sized cerebral cortex with accurate projection neuron diversity.","lang":"eng"}],"ec_funded":1,"article_processing_charge":"No","date_created":"2026-06-09T08:08:18Z","project":[{"call_identifier":"FWF","_id":"264E56E2-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex","grant_number":"M02416"},{"call_identifier":"FP7","name":"Molecular Mechanisms of Cerebral Cortex Development","_id":"25D61E48-B435-11E9-9278-68D0E5697425","grant_number":"618444"},{"call_identifier":"H2020","_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","grant_number":"725780"}],"publication_status":"submitted","department":[{"_id":"SiHi"}],"language":[{"iso":"eng"}],"month":"05","title":"Mtor/Rptor function globally prevents cortical microcephaly and cell-autonomously promotes postnatal neuron survival in cell type specific manner","oa":1,"type":"preprint","main_file_link":[{"url":"https://doi.org/10.64898/2026.05.01.722172","open_access":"1"}],"doi":"10.64898/2026.05.01.722172","publication":"bioRxiv","author":[{"full_name":"Villalba Requena, Ana","last_name":"Villalba Requena","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","orcid":"0000-0002-5615-5277","first_name":"Ana"},{"full_name":"Beattie, Robert J","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87","last_name":"Beattie","orcid":"0000-0002-8483-8753","first_name":"Robert J"},{"orcid":"0000-0002-7462-0048","first_name":"Florian","full_name":"Pauler, Florian","last_name":"Pauler","id":"48EA0138-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Carmen","full_name":"Streicher, Carmen","last_name":"Streicher","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","last_name":"Miranda","first_name":"Osvaldo","orcid":"0000-0001-6618-6889"},{"first_name":"Thomas","last_name":"Krausgruber","full_name":"Krausgruber, Thomas"},{"first_name":"Martin","full_name":"Senekowitsch, Martin","last_name":"Senekowitsch"},{"last_name":"Farlik","full_name":"Farlik, Matthias","first_name":"Matthias"},{"full_name":"Bock, Christoph","last_name":"Bock","first_name":"Christoph"},{"first_name":"Thomas","last_name":"Rülicke","full_name":"Rülicke, Thomas"},{"last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87","full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","first_name":"Simon"}]},{"date_updated":"2026-06-16T08:57:20Z","abstract":[{"lang":"eng","text":"The cerebral cortex consists of immense numbers of neuronal and glial cell-types derived from radial glial progenitor (RGP) cells. How RGPs generate appropriate quantities of distinct cortical cell-types to safeguard a brain of correct size, is not well understood. However, genetic aberration in human, including mutations in PTEN, lead to cortical malformation such as macrocephaly, albeit with unknown etiology. Here we utilized Mosaic Analysis with Double Markers (MADM)-based clonal analysis and single cell phenotyping to decipher the role of Pten in neurogenic and gliogenic RGP lineage progression during cortical ontogeny. While neurogenic RGP lineage progression and projection neuron production was moderately altered in the absence of Pten, cortical astrocyte production was drastically increased. Through genetic epistasis experiments we show that the loss of Pten uncouples astrocyte generation from essential growth factor signaling hubs, funneling into MAPK. Collectively, our results suggest that Pten regulates RGP lineage progression with distinct sequential functions in cortical projection neurogenesis and astrocyte production to ensure the emergence of a correctly-sized cerebral cortex."}],"ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","fulldoi":"https://doi.org/10.64898/2026.05.01.722191","tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"ddc":["570"],"OA_type":"green","has_accepted_license":"1","date_published":"2026-05-05T00:00:00Z","OA_place":"repository","oa_version":"Preprint","_id":"21963","status":"public","citation":{"ieee":"O. Miranda <i>et al.</i>, “Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production,” <i>bioRxiv</i>. .","apa":"Miranda, O., Contreras, X., Pauler, F., Davaatseren, A., Amberg, N., Streicher, C., … Hippenmeyer, S. (n.d.). Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>","ista":"Miranda O, Contreras X, Pauler F, Davaatseren A, Amberg N, Streicher C, Villalba Requena A, Heger A-M, Marie C, Hassan BA, Rülicke T, Hippenmeyer S. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. bioRxiv, <a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","ama":"Miranda O, Contreras X, Pauler F, et al. Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>","mla":"Miranda, Osvaldo, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.64898/2026.05.01.722191\">10.64898/2026.05.01.722191</a>.","short":"O. Miranda, X. Contreras, F. Pauler, A. Davaatseren, N. Amberg, C. Streicher, A. Villalba Requena, A.-M. Heger, C. Marie, B.A. Hassan, T. Rülicke, S. Hippenmeyer, BioRxiv (n.d.).","chicago":"Miranda, Osvaldo, Ximena Contreras, Florian Pauler, Amarbayasgalan Davaatseren, Nicole Amberg, Carmen Streicher, Ana Villalba Requena, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.64898/2026.05.01.722191\">https://doi.org/10.64898/2026.05.01.722191</a>."},"acknowledgement":"We thank Kay-Uwe Wagner (Wayne State University) for generously sharing Jak1/2–flox mouse lines; A.\r\nSommer (VBCF GmbH, NGS Unit) for technical support; N. Kim, V. Mick, S. Schnabl, S. Gobeil, and L.\r\nAndersen for technical assistance; all members of the Hippenmeyer lab for discussion and B. Novitch for\r\ncomments on earlier versions of the manuscript. This research was supported by the Scientific Service Units\r\n(SSU) of IST Austria through resources provided by the Imaging and Optics Facility (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF). O.A.M received support from the Austrian Academy of Sciences\r\nÖAW (DOC 186584), and N.A. from FWF Elise Richter Program (Grant V1041T). This work was also\r\nsupported by IST Austria institutional funds; FWF SFB F78 (Neuro Stem Modulation) to S.H., and the\r\nEuropean Research Council (ERC) under the European Union’s Horizon 2020 research and innovation\r\nprogramme (grant agreement No 725780 LinPro) to S.H.","year":"2026","day":"05","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"corr_author":"1","author":[{"first_name":"Osvaldo","orcid":"0000-0001-6618-6889","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425","last_name":"Miranda"},{"last_name":"Contreras","id":"475990FE-F248-11E8-B48F-1D18A9856A87","full_name":"Contreras, Ximena","first_name":"Ximena"},{"last_name":"Pauler","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","full_name":"Pauler, Florian","orcid":"0000-0002-7462-0048","first_name":"Florian"},{"first_name":"Amarbayasgalan","id":"70ADC922-B424-11E9-99E3-BA18E6697425","last_name":"Davaatseren","full_name":"Davaatseren, Amarbayasgalan"},{"first_name":"Nicole","orcid":"0000-0002-3183-8207","full_name":"Amberg, Nicole","id":"4CD6AAC6-F248-11E8-B48F-1D18A9856A87","last_name":"Amberg"},{"first_name":"Carmen","full_name":"Streicher, Carmen","id":"36BCB99C-F248-11E8-B48F-1D18A9856A87","last_name":"Streicher"},{"orcid":"0000-0002-5615-5277","first_name":"Ana","full_name":"Villalba Requena, Ana","id":"68cb85a0-39f7-11eb-9559-9aaab4f6a247","last_name":"Villalba Requena"},{"first_name":"Anna-Magdalena","last_name":"Heger","id":"4B76FFD2-F248-11E8-B48F-1D18A9856A87","full_name":"Heger, Anna-Magdalena"},{"full_name":"Marie, Corentine","last_name":"Marie","first_name":"Corentine"},{"first_name":"Bassem A.","full_name":"Hassan, Bassem A.","last_name":"Hassan"},{"last_name":"Rülicke","full_name":"Rülicke, Thomas","first_name":"Thomas"},{"orcid":"0000-0003-2279-1061","first_name":"Simon","full_name":"Hippenmeyer, Simon","id":"37B36620-F248-11E8-B48F-1D18A9856A87","last_name":"Hippenmeyer"}],"publication":"bioRxiv","main_file_link":[{"url":"https://doi.org/10.64898/2026.05.01.722191","open_access":"1"}],"doi":"10.64898/2026.05.01.722191","type":"preprint","title":"Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical astrocyte production","oa":1,"department":[{"_id":"SiHi"},{"_id":"PreCl"},{"_id":"GradSch"}],"language":[{"iso":"eng"}],"publication_status":"submitted","month":"05","date_created":"2026-06-09T08:08:53Z","article_processing_charge":"No","project":[{"grant_number":"F7805","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression"},{"grant_number":"725780","call_identifier":"H2020","_id":"260018B0-B435-11E9-9278-68D0E5697425","name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development"}]},{"date_updated":"2026-06-15T23:00:03Z","corr_author":"1","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","abstract":[{"lang":"eng","text":"A Rust library for analyzing dendritic structures using quadric matrices. 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random matrix X with centred i.i.d. entries and we prove that it decays as an inverse second power of the distance between the corresponding eigenvalues. This extends similar results for the complex Gaussian ensemble from Bourgade and Dubach [15], as well as Benaych-Georges and Zeitouni [13], to any i.i.d. matrix ensemble in both symmetry classes. As a main tool, we prove a two-resolvent local law for the Hermitisation of X uniformly in the spectrum with optimal decay rate and optimal dependence on the density near the spectral edge.","lang":"eng"}],"issue":"1","external_id":{"arxiv":["2411.16572"],"isi":["001583178200001"],"oaworkid":["w4413883397"]},"intvolume":"       290","file":[{"file_id":"20947","success":1,"date_created":"2026-01-05T13:05:47Z","file_size":2503887,"file_name":"2026_JourFuncAnalysis_Cipolloni.pdf","relation":"main_file","checksum":"ee53d5e695f0df11e017c8c9242a2b04","access_level":"open_access","creator":"dernst","date_updated":"2026-01-05T13:05:47Z","content_type":"application/pdf"}],"_id":"20328","status":"public","oa_version":"Published Version","isi":1,"arxiv":1,"day":"01","publisher":"Elsevier","acknowledgement":"Partially supported by ERC Advanced Grant “RMTBeyond” No. 101020331. Partially supported by National Key R&D Program of China No. 2024YFA1013503.","citation":{"ista":"Cipolloni G, Erdös L, Xu Y. 2026. Optimal decay of eigenvector overlap for non-Hermitian random matrices. Journal of Functional Analysis. 290(1), 111180.","ama":"Cipolloni G, Erdös L, Xu Y. Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. 2026;290(1). doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>","apa":"Cipolloni, G., Erdös, L., &#38; Xu, Y. (2026). Optimal decay of eigenvector overlap for non-Hermitian random matrices. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>","ieee":"G. Cipolloni, L. Erdös, and Y. Xu, “Optimal decay of eigenvector overlap for non-Hermitian random matrices,” <i>Journal of Functional Analysis</i>, vol. 290, no. 1. Elsevier, 2026.","chicago":"Cipolloni, Giorgio, László Erdös, and Yuanyuan Xu. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">https://doi.org/10.1016/j.jfa.2025.111180</a>.","short":"G. Cipolloni, L. Erdös, Y. Xu, Journal of Functional Analysis 290 (2026).","mla":"Cipolloni, Giorgio, et al. “Optimal Decay of Eigenvector Overlap for Non-Hermitian Random Matrices.” <i>Journal of Functional Analysis</i>, vol. 290, no. 1, 111180, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.jfa.2025.111180\">10.1016/j.jfa.2025.111180</a>."},"year":"2026"},{"publication":"Journal of Combinatorial Theory Series B","author":[{"full_name":"Christoph, Micha","last_name":"Christoph","first_name":"Micha"},{"full_name":"Nenadov, Rajko","last_name":"Nenadov","first_name":"Rajko"},{"first_name":"Kalina H","full_name":"Petrova, Kalina H","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","last_name":"Petrova"}],"corr_author":"1","scopus_import":"1","publication_identifier":{"issn":["0095-8956"],"eissn":["1096-0902"]},"title":"The Hamilton space of pseudorandom graphs","oa":1,"doi":"10.1016/j.jctb.2025.09.002","type":"journal_article","month":"01","page":"254-267","language":[{"iso":"eng"}],"volume":176,"department":[{"_id":"MaKw"}],"publication_status":"published","project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"quality_controlled":"1","date_created":"2025-10-05T22:01:34Z","article_processing_charge":"Yes (via OA deal)","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"We show that if n is odd and p>=Clog n/n, then with high probability Hamilton cycles in G(n,p) span its cycle space. More generally, we show this holds for a class of graphs satisfying certain natural pseudorandom properties. The proof is based on a novel idea of parity-switchers, which can be thought of as analogues of absorbers in the context of cycle spaces. As another application of our method, we show that Hamilton cycles in a near-Dirac graph G, that is, a graph G with odd n vertices and minimum degree n/2+C for sufficiently large constant C, span its cycle space.\r\n"}],"ec_funded":1,"file_date_updated":"2026-01-05T13:29:34Z","date_updated":"2026-01-05T13:29:52Z","OA_place":"publisher","ddc":["510"],"OA_type":"hybrid","date_published":"2026-01-01T00:00:00Z","PlanS_conform":"1","has_accepted_license":"1","article_type":"original","fulldoi":"https://doi.org/10.1016/j.jctb.2025.09.002","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"day":"01","arxiv":1,"isi":1,"citation":{"ista":"Christoph M, Nenadov R, Petrova KH. 2026. The Hamilton space of pseudorandom graphs. Journal of Combinatorial Theory Series B. 176, 254–267.","ama":"Christoph M, Nenadov R, Petrova KH. The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. 2026;176:254-267. doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>","apa":"Christoph, M., Nenadov, R., &#38; Petrova, K. H. (2026). The Hamilton space of pseudorandom graphs. <i>Journal of Combinatorial Theory Series B</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>","ieee":"M. Christoph, R. Nenadov, and K. H. Petrova, “The Hamilton space of pseudorandom graphs,” <i>Journal of Combinatorial Theory Series B</i>, vol. 176. Elsevier, pp. 254–267, 2026.","chicago":"Christoph, Micha, Rajko Nenadov, and Kalina H Petrova. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">https://doi.org/10.1016/j.jctb.2025.09.002</a>.","mla":"Christoph, Micha, et al. “The Hamilton Space of Pseudorandom Graphs.” <i>Journal of Combinatorial Theory Series B</i>, vol. 176, Elsevier, 2026, pp. 254–67, doi:<a href=\"https://doi.org/10.1016/j.jctb.2025.09.002\">10.1016/j.jctb.2025.09.002</a>.","short":"M. Christoph, R. Nenadov, K.H. Petrova, Journal of Combinatorial Theory Series B 176 (2026) 254–267."},"acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Image 1 Part of this research was conducted while the author was at Department of Computer Science, ETH Zürich, Switzerland. This author was supported by grant no. CRSII5 173721 of the Swiss National Science Foundation.","year":"2026","publisher":"Elsevier","_id":"20422","status":"public","oa_version":"Published Version","external_id":{"arxiv":["2402.01447"],"isi":["001585783400001"]},"file":[{"relation":"main_file","access_level":"open_access","checksum":"60676af4af4b3243ba187e7d65440d99","date_updated":"2026-01-05T13:29:34Z","content_type":"application/pdf","creator":"dernst","file_id":"20953","success":1,"file_name":"2026_JourCombTheoryB_Christoph.pdf","file_size":688924,"date_created":"2026-01-05T13:29:34Z"}],"intvolume":"       176"},{"article_processing_charge":"Yes (via OA deal)","date_created":"2025-10-12T22:01:26Z","project":[{"grant_number":"788183","name":"Alpha Shape Theory Extended","_id":"266A2E9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"grant_number":"Z00342","call_identifier":"FWF","name":"Mathematics, Computer Science","_id":"268116B8-B435-11E9-9278-68D0E5697425"},{"grant_number":"I02979-N35","name":"Persistence and stability of geometric complexes","_id":"2561EBF4-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"quality_controlled":"1","related_material":{"record":[{"status":"public","relation":"earlier_version","id":"15090"}]},"page":"24-47","publication_status":"published","volume":75,"language":[{"iso":"eng"}],"department":[{"_id":"HeEd"}],"month":"01","oa":1,"title":"On the size of chromatic Delaunay mosaics","publication_identifier":{"eissn":["1432-0444"],"issn":["0179-5376"]},"type":"journal_article","doi":"10.1007/s00454-025-00778-7","corr_author":"1","scopus_import":"1","publication":"Discrete and Computational Geometry","author":[{"full_name":"Biswas, Ranita","id":"3C2B033E-F248-11E8-B48F-1D18A9856A87","last_name":"Biswas","first_name":"Ranita","orcid":"0000-0002-5372-7890"},{"orcid":"0000-0001-6249-0832","first_name":"Sebastiano","full_name":"Cultrera di Montesano, Sebastiano","last_name":"Cultrera di Montesano","id":"34D2A09C-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0003-0464-3823","first_name":"Ondrej","full_name":"Draganov, Ondrej","id":"2B23F01E-F248-11E8-B48F-1D18A9856A87","last_name":"Draganov"},{"first_name":"Herbert","orcid":"0000-0002-9823-6833","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87"},{"id":"f86f7148-b140-11ec-9577-95435b8df824","last_name":"Saghafian","full_name":"Saghafian, Morteza","first_name":"Morteza"}],"external_id":{"arxiv":["2212.03121"],"isi":["001584166900001"]},"intvolume":"        75","file":[{"checksum":"0addb5c1b78142f9fb453bfa04695400","access_level":"open_access","relation":"main_file","date_updated":"2026-01-05T13:21:20Z","content_type":"application/pdf","creator":"dernst","success":1,"file_id":"20952","file_name":"2026_DiscreteCompGeom_Biswas.pdf","date_created":"2026-01-05T13:21:20Z","file_size":570922}],"status":"public","_id":"20456","oa_version":"Published Version","isi":1,"arxiv":1,"day":"01","publisher":"Springer Nature","acknowledgement":"The fourth author thanks Boris Aronov for insightful discussions on the size of the overlay of Voronoi tessellations. Open access funding provided by Institute of Science and Technology (IST Austria). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme, grant no. 788183, from the Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31, and from the DFG Collaborative Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, Austrian Science Fund (FWF), grant no. I 02979-N35.","year":"2026","citation":{"ama":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. 2026;75:24-47. doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>","ista":"Biswas R, Cultrera di Montesano S, Draganov O, Edelsbrunner H, Saghafian M. 2026. On the size of chromatic Delaunay mosaics. Discrete and Computational Geometry. 75, 24–47.","apa":"Biswas, R., Cultrera di Montesano, S., Draganov, O., Edelsbrunner, H., &#38; Saghafian, M. (2026). On the size of chromatic Delaunay mosaics. <i>Discrete and Computational Geometry</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>","ieee":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, and M. Saghafian, “On the size of chromatic Delaunay mosaics,” <i>Discrete and Computational Geometry</i>, vol. 75. Springer Nature, pp. 24–47, 2026.","chicago":"Biswas, Ranita, Sebastiano Cultrera di Montesano, Ondrej Draganov, Herbert Edelsbrunner, and Morteza Saghafian. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1007/s00454-025-00778-7\">https://doi.org/10.1007/s00454-025-00778-7</a>.","short":"R. Biswas, S. Cultrera di Montesano, O. Draganov, H. Edelsbrunner, M. Saghafian, Discrete and Computational Geometry 75 (2026) 24–47.","mla":"Biswas, Ranita, et al. “On the Size of Chromatic Delaunay Mosaics.” <i>Discrete and Computational Geometry</i>, vol. 75, Springer Nature, 2026, pp. 24–47, doi:<a href=\"https://doi.org/10.1007/s00454-025-00778-7\">10.1007/s00454-025-00778-7</a>."},"PlanS_conform":"1","OA_type":"hybrid","has_accepted_license":"1","date_published":"2026-01-01T00:00:00Z","ddc":["510"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","fulldoi":"https://doi.org/10.1007/s00454-025-00778-7","OA_place":"publisher","date_updated":"2026-01-05T13:21:56Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Given a locally finite set A⊆Rd and a coloring χ:A→{0,1,…,s}, we introduce the chromatic Delaunay mosaic of χ, which is a Delaunay mosaic in Rs+d that represents how points of different colors mingle. Our main results are bounds on the size of the chromatic Delaunay mosaic, in which we assume that d and s are constants. For example, if A is finite with n=#A, and the coloring is random, then the chromatic Delaunay mosaic has O(n⌈d/2⌉) cells in expectation. In contrast, for Delone sets and Poisson point processes in Rd, the expected number of cells within a closed ball is only a constant times the number of points in this ball. Furthermore, in R2 all colorings of a dense set of n points have chromatic Delaunay mosaics of size O(n). This encourages the use of chromatic Delaunay mosaics in applications.","lang":"eng"}],"ec_funded":1,"file_date_updated":"2026-01-05T13:21:20Z"},{"isi":1,"day":"01","arxiv":1,"publisher":"Elsevier","year":"2026","citation":{"ista":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. 2026. Odd-Ramsey numbers of complete bipartite graphs. European Journal of Combinatorics. 131, 104235.","ama":"Boyadzhiyska S, Das S, Lesgourgues T, Petrova KH. Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. 2026;131. doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>","ieee":"S. Boyadzhiyska, S. Das, T. Lesgourgues, and K. H. Petrova, “Odd-Ramsey numbers of complete bipartite graphs,” <i>European Journal of Combinatorics</i>, vol. 131. Elsevier, 2026.","apa":"Boyadzhiyska, S., Das, S., Lesgourgues, T., &#38; Petrova, K. H. (2026). Odd-Ramsey numbers of complete bipartite graphs. <i>European Journal of Combinatorics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>","chicago":"Boyadzhiyska, Simona, Shagnik Das, Thomas Lesgourgues, and Kalina H Petrova. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">https://doi.org/10.1016/j.ejc.2025.104235</a>.","short":"S. Boyadzhiyska, S. Das, T. Lesgourgues, K.H. Petrova, European Journal of Combinatorics 131 (2026).","mla":"Boyadzhiyska, Simona, et al. “Odd-Ramsey Numbers of Complete Bipartite Graphs.” <i>European Journal of Combinatorics</i>, vol. 131, 104235, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.ejc.2025.104235\">10.1016/j.ejc.2025.104235</a>."},"acknowledgement":"The authors would like to thank Gilles Zémor for a helpful clarification on [3], Deepak Bal and Patrick Bennett for bringing [25] to their attention, and both referees for several helpful comments.\r\nS.B.: Most of this research was conducted while the author was at the School of Mathematics, University of Birmingham, Birmingham, United Kingdom. The research leading to these results was supported by EPSRC, United Kingdom, grant no. EP/V048287/1 and by ERC Advanced Grants “GeoScape”, no. 882971 and “ERMiD”, no. 101054936. There are no additional data beyond that contained within the main manuscript.\r\nS.D.: Research supported by Taiwan NSTC grants 111-2115-M-002-009-MY2 and 113-2628-M-002-008-MY4.\r\nK.P.: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413. Parts of this research was conducted while K.P. was at the Department of Computer Science, ETH Zürich, Switzerland, supported by Swiss National Science Foundation, Switzerland , grant no. CRSII5 173721.","_id":"20482","status":"public","oa_version":"Published Version","external_id":{"arxiv":["2410.05887"],"isi":["001573380700001"]},"intvolume":"       131","file":[{"file_name":"2026_EuropJourCombinatorics_Boyadzhiyska.pdf","file_size":563029,"date_created":"2026-01-05T13:34:40Z","success":1,"file_id":"20954","content_type":"application/pdf","date_updated":"2026-01-05T13:34:40Z","creator":"dernst","access_level":"open_access","checksum":"52883daa217398396cbf9b8ad9ddae92","relation":"main_file"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ec_funded":1,"file_date_updated":"2026-01-05T13:34:40Z","abstract":[{"text":"In his study of graph codes, Alon introduced the concept of the odd-Ramsey number of a family of graphs H in Kn, defined as the minimum number of colours needed to colour the edges of K so that every copy of a graph H E H intersects some colour class in an odd number of edges. In this paper, we focus on complete bipartite graphs. First, we completely resolve the problem when H is the family of all spanning complete bipartite graphs on n vertices. We then focus on its subfamilies, that is, {Kt,n-t : t E T} for a fixed set of integers T c [[n/2]]. We prove that the odd-Ramsey problem is equivalent to determining the maximum dimension of a linear binary code avoiding codewords of given weights, and leverage known results from coding theory to deduce asymptotically tight bounds in our setting. We conclude with bounds for the odd-Ramsey numbers of fixed (that is, non-spanning) complete bipartite subgraphs.","lang":"eng"}],"date_updated":"2026-01-05T13:34:48Z","OA_place":"publisher","PlanS_conform":"1","has_accepted_license":"1","OA_type":"hybrid","date_published":"2026-01-01T00:00:00Z","ddc":["500"],"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","fulldoi":"https://doi.org/10.1016/j.ejc.2025.104235","month":"01","publication_status":"published","volume":131,"department":[{"_id":"MaKw"}],"language":[{"iso":"eng"}],"project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"}],"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","date_created":"2025-10-16T13:14:34Z","publication":"European Journal of Combinatorics","author":[{"full_name":"Boyadzhiyska, Simona","last_name":"Boyadzhiyska","first_name":"Simona"},{"first_name":"Shagnik","full_name":"Das, Shagnik","last_name":"Das"},{"first_name":"Thomas","last_name":"Lesgourgues","full_name":"Lesgourgues, Thomas"},{"first_name":"Kalina H","full_name":"Petrova, Kalina H","last_name":"Petrova","id":"554ff4e4-f325-11ee-b0c4-a10dbd523381"}],"corr_author":"1","scopus_import":"1","article_number":"104235","title":"Odd-Ramsey numbers of complete bipartite graphs","oa":1,"publication_identifier":{"issn":["0195-6698"]},"type":"journal_article","doi":"10.1016/j.ejc.2025.104235"},{"date_updated":"2026-06-24T08:37:00Z","abstract":[{"text":"Modern AI systems increasingly rely on opaque, highly complex models whose inner workings remain inaccessible even to experts. This opacity creates challenges for trust, accountability, and compliance with\r\nemerging regulatory expectations such as the “right to an explanation”. While traditional explainability methods—feature attributions, counterfactuals, surrogate models—and interpretable model classes provide valuable insights for engineers, they often fall short of delivering the contextual, conversational explanations that\r\nreal users expect. Large Language Models (LLMs) offer a promising new avenue for explanation due to their\r\nability to engage interactively, adapt to user needs, and translate technical outputs into more accessible reasoning. However, their tendencies toward hallucination, conflict avoidance, and oversimplification introduce\r\nserious risks when used as explanatory agents. This paper analyzes these opportunities and limitations, examines verification strategies for ensuring explanation fidelity, and situates LLM-generated explanations within\r\nbroader concerns about public trust. The paper concludes by outlining best practices and future research directions for building robust, verifiable, and human-aligned explanation systems.","lang":"eng"}],"ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Explainable AI","Large Language Models","Trust in AI"],"fulldoi":"https://doi.org/10.5220/0014483200004052","OA_type":"green","date_published":"2026-04-01T00:00:00Z","OA_place":"repository","oa_version":"Accepted Version","status":"public","_id":"22103","researchdata_availability":"no","publisher":"Science and Technology Publications","year":"2026","acknowledgement":"This work has been supported by the European Research Council under Grant No.: ERC-2020-AdG\r\n101020093. LLM–based tools have been used as\r\nwriting assistance to help improve presentation.\r\n","citation":{"mla":"Cano Cordoba, Filip. “Explaining Decisions One Conversation at a Time: Opportunities and Risks of LLMs as Explainability Assistants.” <i>Proceedings of the 18th International Conference on Agents and Artificial Intelligence</i>, vol. 5, Science and Technology Publications, 2026, pp. 4689–96, doi:<a href=\"https://doi.org/10.5220/0014483200004052\">10.5220/0014483200004052</a>.","short":"F. Cano Cordoba, in:, Proceedings of the 18th International Conference on Agents and Artificial Intelligence, Science and Technology Publications, 2026, pp. 4689–4696.","chicago":"Cano Cordoba, Filip. “Explaining Decisions One Conversation at a Time: Opportunities and Risks of LLMs as Explainability Assistants.” In <i>Proceedings of the 18th International Conference on Agents and Artificial Intelligence</i>, 5:4689–96. Science and Technology Publications, 2026. <a href=\"https://doi.org/10.5220/0014483200004052\">https://doi.org/10.5220/0014483200004052</a>.","apa":"Cano Cordoba, F. (2026). Explaining decisions one conversation at a time: Opportunities and risks of LLMs as explainability assistants. In <i>Proceedings of the 18th International Conference on Agents and Artificial Intelligence</i> (Vol. 5, pp. 4689–4696). Marbella, Spain: Science and Technology Publications. <a href=\"https://doi.org/10.5220/0014483200004052\">https://doi.org/10.5220/0014483200004052</a>","ieee":"F. Cano Cordoba, “Explaining decisions one conversation at a time: Opportunities and risks of LLMs as explainability assistants,” in <i>Proceedings of the 18th International Conference on Agents and Artificial Intelligence</i>, Marbella, Spain, 2026, vol. 5, pp. 4689–4696.","ista":"Cano Cordoba F. 2026. Explaining decisions one conversation at a time: Opportunities and risks of LLMs as explainability assistants. Proceedings of the 18th International Conference on Agents and Artificial Intelligence. ICAART: International Conference on Agents and Artificial Intelligence vol. 5, 4689–4696.","ama":"Cano Cordoba F. Explaining decisions one conversation at a time: Opportunities and risks of LLMs as explainability assistants. In: <i>Proceedings of the 18th International Conference on Agents and Artificial Intelligence</i>. Vol 5. Science and Technology Publications; 2026:4689-4696. doi:<a href=\"https://doi.org/10.5220/0014483200004052\">10.5220/0014483200004052</a>"},"das_tickbox":"0","day":"01","intvolume":"         5","scopus_import":"1","conference":{"start_date":"2026-03-05","location":"Marbella, Spain","end_date":"2026-03-08","name":"ICAART: International Conference on Agents and Artificial Intelligence"},"corr_author":"1","author":[{"id":"708cad98-e86a-11ef-8098-bdae2d7c6af1","last_name":"Cano Cordoba","full_name":"Cano Cordoba, Filip","first_name":"Filip","orcid":"0000-0002-0783-904X"}],"publication":"Proceedings of the 18th International Conference on Agents and Artificial Intelligence","type":"conference","doi":"10.5220/0014483200004052","main_file_link":[{"url":"https://filipcano.org/files/icaart26llm.pdf","open_access":"1"}],"title":"Explaining decisions one conversation at a time: Opportunities and risks of LLMs as explainability assistants","oa":1,"publication_identifier":{"eissn":["2184-433X"],"isbn":["9789897587962"],"issn":["2184-3589"]},"publication_status":"published","department":[{"_id":"ToHe"}],"volume":5,"language":[{"iso":"eng"}],"page":"4689-4696","month":"04","article_processing_charge":"No","date_created":"2026-06-21T22:03:00Z","supplementarymaterial":"no","quality_controlled":"1","project":[{"grant_number":"101020093","call_identifier":"H2020","name":"Vigilant Algorithmic Monitoring of Software","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}]},{"date_created":"2026-03-11T10:40:08Z","article_processing_charge":"Yes","department":[{"_id":"VeSu"}],"language":[{"iso":"eng"}],"publication_status":"epub_ahead","month":"05","publication_identifier":{"eissn":["2397-4648"]},"oa":1,"title":"Linear magneto-birefringence as a probe of altermagnetism","main_file_link":[{"url":"https://doi.org/10.1038/s41535-026-00901-8","open_access":"1"}],"doi":"10.1038/s41535-026-00901-8","type":"journal_article","corr_author":"1","publication":"npj Quantum Materials","author":[{"id":"23cb1cf6-2c7a-11ef-91a4-f72fc19f20b3","last_name":"Sunko","full_name":"Sunko, Veronika","orcid":"0000-0003-2724-3523","first_name":"Veronika"},{"first_name":"J.","full_name":"Orenstein, J.","last_name":"Orenstein"}],"external_id":{"arxiv":["2511.16421"]},"status":"public","_id":"21437","oa_version":"Published Version","arxiv":1,"day":"30","acknowledgement":"We thank Nicola Spaldin and Marc Vila for valuable discussions. J.O. received support from the Quantum Materials (KC2202) program under the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences, Materials Sciences and Engineering Division under Contract No. DE-AC02-05CH11231, and the Gordon and Betty Moore Foundation's EPiQS Initiative through Grant GBMF4537 to J.O. at UC Berkeley.","citation":{"apa":"Sunko, V., &#38; Orenstein, J. (2026). Linear magneto-birefringence as a probe of altermagnetism. <i>Npj Quantum Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41535-026-00901-8\">https://doi.org/10.1038/s41535-026-00901-8</a>","ieee":"V. Sunko and J. Orenstein, “Linear magneto-birefringence as a probe of altermagnetism,” <i>npj Quantum Materials</i>. Springer Nature, 2026.","ama":"Sunko V, Orenstein J. Linear magneto-birefringence as a probe of altermagnetism. <i>npj Quantum Materials</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41535-026-00901-8\">10.1038/s41535-026-00901-8</a>","ista":"Sunko V, Orenstein J. 2026. Linear magneto-birefringence as a probe of altermagnetism. npj Quantum Materials.","mla":"Sunko, Veronika, and J. Orenstein. “Linear Magneto-Birefringence as a Probe of Altermagnetism.” <i>Npj Quantum Materials</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41535-026-00901-8\">10.1038/s41535-026-00901-8</a>.","short":"V. Sunko, J. Orenstein, Npj Quantum Materials (2026).","chicago":"Sunko, Veronika, and J. Orenstein. “Linear Magneto-Birefringence as a Probe of Altermagnetism.” <i>Npj Quantum Materials</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41535-026-00901-8\">https://doi.org/10.1038/s41535-026-00901-8</a>."},"year":"2026","publisher":"Springer Nature","ddc":["530"],"has_accepted_license":"1","OA_type":"gold","date_published":"2026-05-30T00:00:00Z","article_type":"original","fulldoi":"https://doi.org/10.1038/s41535-026-00901-8","tmp":{"image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"OA_place":"publisher","date_updated":"2026-06-24T10:31:05Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"Altermagnets are a class of collinear magnets that exhibit non-relativistic spin splitting (NRSS) of electronic bands in the absence of net magnetization. Their potential to generate large spin polarization without spin-orbit coupling has created strong interest in probes that access the underlying order parameter directly. In this Perspective, we show that linear magneto-birefringence (LMB) provides a natural and broadly applicable route to detecting altermagnetic order. Building on the correspondence between the momentum-space structure of NRSS and the ferroic ordering of magnetic multipoles in real space, we demonstrate how $d$-wave and $g$-wave NRSS textures yield distinct LMB responses. We present a symmetry-based framework that identifies the optical geometries and field configurations required to isolate specific multipole components, enabling domain imaging and providing benchmarks for theoretical models of LMB.","lang":"eng"}]},{"pmid":1,"publication_identifier":{"issn":["1936-0851"],"eissn":["1936-086X"]},"title":"On-chip tuning of superconductivity in fullerides via current-driven Rb+ intercalation","oa":1,"doi":"10.1021/acsnano.6c02466","type":"journal_article","publication":"ACS Nano","author":[{"full_name":"Shchukin, Konstantin P.","last_name":"Shchukin","first_name":"Konstantin P."},{"full_name":"Gallego Lacey, Oliver N.","last_name":"Gallego Lacey","first_name":"Oliver N."},{"first_name":"Baptiste","orcid":"0000-0001-5524-596X","full_name":"Coquinot, Baptiste","last_name":"Coquinot","id":"f8417bd4-f599-11ee-a482-b927e3ed1e8e"},{"last_name":"Jakowski","full_name":"Jakowski, Jacek","first_name":"Jacek"},{"first_name":"Jingsong","last_name":"Huang","full_name":"Huang, Jingsong"},{"first_name":"Patrik","full_name":"Staudenmayer, Patrik","last_name":"Staudenmayer"},{"full_name":"Falke, Yannic","last_name":"Falke","first_name":"Yannic"},{"full_name":"Pandeya, Ram Prakash","last_name":"Pandeya","first_name":"Ram Prakash"},{"first_name":"Alexander","full_name":"Grüneis, Alexander","last_name":"Grüneis"}],"scopus_import":"1","quality_controlled":"1","date_created":"2026-06-28T22:01:34Z","supplementarymaterial":"yes","article_processing_charge":"Yes (via OA deal)","month":"06","page":"17360-17372","department":[{"_id":"MiLe"}],"language":[{"iso":"eng"}],"volume":20,"publication_status":"published","OA_place":"publisher","ddc":["530"],"OA_type":"hybrid","date_published":"2026-06-23T00:00:00Z","has_accepted_license":"1","PlanS_conform":"1","article_type":"original","fulldoi":"https://doi.org/10.1021/acsnano.6c02466","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"keyword":["fulleride","intercalation","alkali metal","superconductivity","Raman"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"An in-operando electro-intercalation method for the on-chip synthesis of alkali-metal-intercalated materials and their Raman spectroscopic and transport characterization in ultrahigh vacuum (UHV) is developed. We apply this method to synthesize fulleride superconductors via Rb+ intercalation into a C60 film. During the intercalation, we monitor the stoichiometry via UHV-Raman spectroscopy and probe superconductivity via transport measurements. An increase of the superconducting transition temperature from 7.0 K to 14.5 K is observed when the stoichiometry is tuned from Rb2.7C60 to Rb3C60. In our experiment, an ionic Rb+ flux into the host material is induced by an applied electronic current via a Butler–Volmer-type mechanism. Electro-intercalation captivates through improved stoichiometric precision, the ability to smoothly vary stoichiometry via duration of current application, and the absence of a lower limit of the volume of the host material. It represents a powerful concept for the on-chip synthesis of intercalated materials, battery research, and beyond.","lang":"eng"}],"file_date_updated":"2026-06-29T08:58:12Z","date_updated":"2026-06-29T09:00:33Z","external_id":{"pmid":["42260723"]},"issue":"24","file":[{"creator":"dernst","content_type":"application/pdf","date_updated":"2026-06-29T08:58:12Z","access_level":"open_access","checksum":"01ec8ee6fab7bf563df7af13f6b43045","relation":"main_file","file_size":6290296,"date_created":"2026-06-29T08:58:12Z","file_name":"2026_ACSNano_Shchukin.pdf","success":1,"file_id":"22150"}],"intvolume":"        20","day":"23","das_tickbox":"0","citation":{"ieee":"K. P. Shchukin <i>et al.</i>, “On-chip tuning of superconductivity in fullerides via current-driven Rb+ intercalation,” <i>ACS Nano</i>, vol. 20, no. 24. American Chemical Society, pp. 17360–17372, 2026.","apa":"Shchukin, K. P., Gallego Lacey, O. N., Coquinot, B., Jakowski, J., Huang, J., Staudenmayer, P., … Grüneis, A. (2026). On-chip tuning of superconductivity in fullerides via current-driven Rb+ intercalation. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.6c02466\">https://doi.org/10.1021/acsnano.6c02466</a>","ista":"Shchukin KP, Gallego Lacey ON, Coquinot B, Jakowski J, Huang J, Staudenmayer P, Falke Y, Pandeya RP, Grüneis A. 2026. On-chip tuning of superconductivity in fullerides via current-driven Rb+ intercalation. ACS Nano. 20(24), 17360–17372.","ama":"Shchukin KP, Gallego Lacey ON, Coquinot B, et al. On-chip tuning of superconductivity in fullerides via current-driven Rb+ intercalation. <i>ACS Nano</i>. 2026;20(24):17360-17372. doi:<a href=\"https://doi.org/10.1021/acsnano.6c02466\">10.1021/acsnano.6c02466</a>","short":"K.P. Shchukin, O.N. Gallego Lacey, B. Coquinot, J. Jakowski, J. Huang, P. Staudenmayer, Y. Falke, R.P. Pandeya, A. Grüneis, ACS Nano 20 (2026) 17360–17372.","mla":"Shchukin, Konstantin P., et al. “On-Chip Tuning of Superconductivity in Fullerides via Current-Driven Rb+ Intercalation.” <i>ACS Nano</i>, vol. 20, no. 24, American Chemical Society, 2026, pp. 17360–72, doi:<a href=\"https://doi.org/10.1021/acsnano.6c02466\">10.1021/acsnano.6c02466</a>.","chicago":"Shchukin, Konstantin P., Oliver N. Gallego Lacey, Baptiste Coquinot, Jacek Jakowski, Jingsong Huang, Patrik Staudenmayer, Yannic Falke, Ram Prakash Pandeya, and Alexander Grüneis. “On-Chip Tuning of Superconductivity in Fullerides via Current-Driven Rb+ Intercalation.” <i>ACS Nano</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsnano.6c02466\">https://doi.org/10.1021/acsnano.6c02466</a>."},"acknowledgement":"A.G. and K.P.S. acknowledge the DFG through CRC 1238 (277146847, A01) and DFG project SE 2575. K.P.S., P.S., and A.G. would like to thank the Center for Micro- and Nanostructures (ZMNS) for providing the cleanroom facilities. K.P.S. thanks Daniele Nazari for help with ALD of Al2O3 films. Financial support from FFG Austria (CrystalGate) is acknowledged. A.G. thanks John Weaver for discussions about the structure of RbxC60. B.C. acknowledges support from the NOMIS Foundation. First-principles simulations were supported as part of user project CNMS2025-R-03182 at the Center for Nanophase Materials Sciences (CNMS), which is a US Department of Energy, Office of Science User Facility at Oak Ridge National Laboratory. J.J. and J.H. acknowledge the computational resources provided by the ACCESS (Advanced Cyberinfrastructure Coordination Ecosystem: Services & Support) program through allocation TG-DMR110037; the National Energy Research Scientific Computing Center (NERSC), a DOE Office of Science User Facility supported under Contract No. DE-AC02-05CH11231, through NERSC award BES-ERCAP0031261; and the Compute and Data Environment for Science (CADES) Baseline at Oak Ridge National Laboratory, supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC05-00OR22725. The authors acknowledge TU Wien Bibliothek for financial support through its Open access funding provided by Technische Universitat Wien.","year":"2026","publisher":"American Chemical Society","_id":"22145","status":"public","researchdata_availability":"no","oa_version":"Published Version"},{"article_number":"rnag126","publication_identifier":{"eissn":["1687-0247"],"issn":["1073-7928"]},"oa":1,"title":"On random matrices with large corank","doi":"10.1093/imrn/rnag126","type":"journal_article","publication":"International Mathematics Research Notices","author":[{"full_name":"Hunter, Zach","last_name":"Hunter","first_name":"Zach"},{"orcid":"0000-0002-4003-7567","first_name":"Matthew Alan","full_name":"Kwan, Matthew Alan","last_name":"Kwan","id":"5fca0887-a1db-11eb-95d1-ca9d5e0453b3"},{"last_name":"Sauermann","full_name":"Sauermann, Lisa","first_name":"Lisa"},{"first_name":"Mehtaab","full_name":"Sawhney, Mehtaab","last_name":"Sawhney"}],"corr_author":"1","scopus_import":"1","project":[{"_id":"bd95085b-d553-11ed-ba76-e55d3349be45","name":"Randomness and structure in combinatorics","grant_number":"101076777"}],"quality_controlled":"1","supplementarymaterial":"no","date_created":"2026-06-28T22:01:35Z","article_processing_charge":"Yes (via OA deal)","month":"06","volume":2026,"language":[{"iso":"eng"}],"department":[{"_id":"MaKw"}],"publication_status":"published","OA_place":"publisher","ddc":["500"],"has_accepted_license":"1","PlanS_conform":"1","OA_type":"hybrid","date_published":"2026-06-01T00:00:00Z","article_type":"original","fulldoi":"https://doi.org/10.1093/imrn/rnag126","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"Let 1 ≤ k ≤ n and M be a random n × n matrix with independent uniformly random {±1}-entries. We\r\nshow that there exists an absolute constant c > 0 such that\r\nP[rank(M) ≤ n − k] ≤ exp(−cnk).\r\nThis confirms a well-known prediction in the area, extending a result of Rudelson (who previously\r\nproved this same result under the restriction k ≤ √n, via different methods)."}],"file_date_updated":"2026-06-29T09:15:15Z","date_updated":"2026-06-29T09:19:14Z","external_id":{"arxiv":["2510.12933"]},"issue":"12","file":[{"file_id":"22151","success":1,"date_created":"2026-06-29T09:15:15Z","file_size":524993,"file_name":"2026_IMRN_Hunter.pdf","relation":"main_file","checksum":"396b47d0532d7ea509f8cd30f11392a8","access_level":"open_access","creator":"dernst","date_updated":"2026-06-29T09:15:15Z","content_type":"application/pdf"}],"intvolume":"      2026","das_tickbox":"0","arxiv":1,"day":"01","year":"2026","acknowledgement":"Z.H. was supported by SNSF grant 200021-228014. M.K. was supported by ERC Starting Grant “RANDSTRUCT” No. 101076777. L.S. was supported by the Deutsche Forschungsgemeinschaft (DFG, German\r\nResearch Foundation)—CRC 1720–539309657. This research was conducted during the period M.S. served\r\nas a Clay Research Fellow. This work began when the authors were visiting Mathematisches Forschungsinstitut Oberwolfach, which\r\nprovided ideal working conditions. M.S. thanks Vishesh Jain for initial discussions regarding the problem.\r\nWe also thank the anonymous referee for helpful comments.","citation":{"chicago":"Hunter, Zach, Matthew Alan Kwan, Lisa Sauermann, and Mehtaab Sawhney. “On Random Matrices with Large Corank.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2026. <a href=\"https://doi.org/10.1093/imrn/rnag126\">https://doi.org/10.1093/imrn/rnag126</a>.","mla":"Hunter, Zach, et al. “On Random Matrices with Large Corank.” <i>International Mathematics Research Notices</i>, vol. 2026, no. 12, rnag126, Oxford University Press, 2026, doi:<a href=\"https://doi.org/10.1093/imrn/rnag126\">10.1093/imrn/rnag126</a>.","short":"Z. Hunter, M.A. Kwan, L. Sauermann, M. Sawhney, International Mathematics Research Notices 2026 (2026).","ista":"Hunter Z, Kwan MA, Sauermann L, Sawhney M. 2026. On random matrices with large corank. International Mathematics Research Notices. 2026(12), rnag126.","ama":"Hunter Z, Kwan MA, Sauermann L, Sawhney M. On random matrices with large corank. <i>International Mathematics Research Notices</i>. 2026;2026(12). doi:<a href=\"https://doi.org/10.1093/imrn/rnag126\">10.1093/imrn/rnag126</a>","apa":"Hunter, Z., Kwan, M. A., Sauermann, L., &#38; Sawhney, M. (2026). On random matrices with large corank. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rnag126\">https://doi.org/10.1093/imrn/rnag126</a>","ieee":"Z. Hunter, M. A. Kwan, L. Sauermann, and M. Sawhney, “On random matrices with large corank,” <i>International Mathematics Research Notices</i>, vol. 2026, no. 12. Oxford University Press, 2026."},"publisher":"Oxford University Press","status":"public","_id":"22147","researchdata_availability":"no","oa_version":"Published Version"},{"tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"article_type":"original","fulldoi":"https://doi.org/10.1038/s41467-026-71914-x","OA_type":"gold","date_published":"2026-06-23T00:00:00Z","PlanS_conform":"1","has_accepted_license":"1","ddc":["570"],"DOAJ_listed":"1","OA_place":"publisher","date_updated":"2026-07-01T06:47:49Z","file_date_updated":"2026-07-01T06:46:06Z","abstract":[{"text":"Hippocampal CA3 pyramidal neurons (PNs) form the largest autoassociative network in the mammalian brain. Whether CA3–CA3 recurrent connectivity is genetically preconfigured or environmentally shaped during ongoing memory storage is currently unknown. To address this question, we performed multicellular patch-clamp-based circuit mapping of up to eight CA3 PNs in the mouse hippocampus at multiple postnatal time points (P7–8, P18–25, and P45–50). Here, we show that the hippocampal CA3 network undergoes a developmental transformation from local, dense, and random connectivity to a distributed, sparse, and structured configuration. Thus, sparse and structured connectivity may emerge via experience-dependent mechanisms. In parallel, the strength of single synapses is downregulated; single synaptic events are sufficient to trigger postsynaptic spiking early in development, whereas spatial summation of several inputs is required at later time points. Biologically inspired models of memory storage by Hebbian synaptic plasticity and retrieval via pattern completion suggest that developmental changes improve specific aspects of memory storage and retrieval. Our results imply a developmental transformation of the neuronal code and the memory functions in the hippocampal CA3 network.</jats:p>","lang":"eng"}],"ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","dataavailabilitystatement":"Source data are provided with this paper. Additional original data are available from the corresponding author upon request. Code is available from https://doi.org/10.15479/AT-ISTA-21442 under the link https://research-explorer.ista.ac.at/download/21442/21443/ca3simu-vargas2026v1.tar.gz","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"M-Shop"},{"_id":"ScienComp"}],"intvolume":"        17","file":[{"content_type":"application/pdf","date_updated":"2026-07-01T06:46:06Z","creator":"dernst","checksum":"d0b0093493926985b4c268662ff4d556","access_level":"open_access","relation":"main_file","file_name":"2026_NatureComm_VargasBarroso.pdf","date_created":"2026-07-01T06:46:06Z","file_size":18304997,"success":1,"file_id":"22231"}],"external_id":{"pmid":["42014695"]},"oa_version":"Published Version","researchdata_availability":"yes","_id":"22229","status":"public","publisher":"Springer Nature","citation":{"short":"V.M. Vargas Barroso, J. Watson, A.C. Navas Olivé, A. Schlögl, P.M. Jonas, Nature Communications 17 (2026).","mla":"Vargas Barroso, Victor M., et al. “Developmental Emergence of Sparse and Structured Synaptic Connectivity in the Hippocampal CA3 Memory Circuit.” <i>Nature Communications</i>, vol. 17, 5540, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41467-026-71914-x\">10.1038/s41467-026-71914-x</a>.","chicago":"Vargas Barroso, Victor M, Jake Watson, Andrea C Navas Olivé, Alois Schlögl, and Peter M Jonas. “Developmental Emergence of Sparse and Structured Synaptic Connectivity in the Hippocampal CA3 Memory Circuit.” <i>Nature Communications</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41467-026-71914-x\">https://doi.org/10.1038/s41467-026-71914-x</a>.","apa":"Vargas Barroso, V. M., Watson, J., Navas Olivé, A. C., Schlögl, A., &#38; Jonas, P. M. (2026). Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-026-71914-x\">https://doi.org/10.1038/s41467-026-71914-x</a>","ieee":"V. M. Vargas Barroso, J. Watson, A. C. Navas Olivé, A. Schlögl, and P. M. Jonas, “Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit,” <i>Nature Communications</i>, vol. 17. Springer Nature, 2026.","ista":"Vargas Barroso VM, Watson J, Navas Olivé AC, Schlögl A, Jonas PM. 2026. Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit. Nature Communications. 17, 5540.","ama":"Vargas Barroso VM, Watson J, Navas Olivé AC, Schlögl A, Jonas PM. Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit. <i>Nature Communications</i>. 2026;17. doi:<a href=\"https://doi.org/10.1038/s41467-026-71914-x\">10.1038/s41467-026-71914-x</a>"},"year":"2026","acknowledgement":"We thank Jose Guzman, Simon Hippenmeyer, and Tim Vogels for critically reading the manuscript, Jozsef Csicsvari for useful discussions, Florian Marr for technical assistance, and Eleftheria Kralli-Beller for manuscript editing. This research was supported by the Scientific Services Units (SSUs) of ISTA: the preclinical facility (PCF) provided housing and breeding of the animals, the imaging and optics facility (IOF) offered technical training and state of the art equipment, the Miba machine shop contributed to the construction and maintenance of multicellular recording setups, and the scientific computing unit helped with the large-scale simulations. The project received funding from the European Union’s Horizon 2020 research and innovation programme (ERC Advanced Grants No 692692 GIANTSYN and 101199096 CA3-SYNGRAM to P.J.; Marie Skłodowska-Curie Grant 754411 to V.V.B.; Marie Skłodowska-Curie Grant 101026635 to J.F.W.), the Fond zur Förderung der Wissenschaftlichen Forschung (P 36232-B, PAT4178023, and 10.55776/CoE16 to P.J.), and the Nomis Foundation (fellowship to A.N.-O.). V.V.B. received funding from a CONACyT fellowship (289638).","das_tickbox":"1","day":"23","type":"journal_article","doi":"10.1038/s41467-026-71914-x","title":"Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit","oa":1,"publication_identifier":{"eissn":["2041-1723"]},"pmid":1,"article_number":"5540","scopus_import":"1","corr_author":"1","author":[{"last_name":"Vargas Barroso","id":"2F55A9DE-F248-11E8-B48F-1D18A9856A87","full_name":"Vargas Barroso, Victor M","first_name":"Victor M"},{"full_name":"Watson, Jake","id":"63836096-4690-11EA-BD4E-32803DDC885E","last_name":"Watson","orcid":"0000-0002-8698-3823","first_name":"Jake"},{"full_name":"Navas Olivé, Andrea C","id":"739d26c9-52e8-11ee-8d72-f14d3893b4ce","last_name":"Navas Olivé","first_name":"Andrea C","orcid":"0000-0002-9280-8597"},{"id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","last_name":"Schlögl","full_name":"Schlögl, Alois","first_name":"Alois","orcid":"0000-0002-5621-8100"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas","full_name":"Jonas, Peter M","first_name":"Peter M","orcid":"0000-0001-5001-4804"}],"publication":"Nature Communications","article_processing_charge":"Yes","date_created":"2026-06-30T13:05:52Z","supplementarymaterial":"yes","quality_controlled":"1","related_material":{"record":[{"relation":"research_data","id":"21442","status":"public"}]},"project":[{"grant_number":"692692","call_identifier":"H2020","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse"},{"_id":"e62b56fe-ab3c-11f0-94c7-d181dd352b3b","name":"Synaptic mechanisms of engram storage and retrieval in CA3 hippocampal microcircuits","grant_number":"101199096"},{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"},{"grant_number":"101026635","_id":"fc2be41b-9c52-11eb-aca3-faa90aa144e9","name":"Synaptic computations of the hippocampal CA3 circuitry","call_identifier":"H2020"},{"grant_number":"P36232","_id":"bd88be38-d553-11ed-ba76-81d5a70a6ef5","name":"Mechanisms of GABA release in hippocampal circuits"},{"_id":"8d9195e9-16d5-11f0-9cad-d075be887a1e","name":"Synaptic networks of human brain","grant_number":"PAT 4178023"},{"name":"Reglas de Conectividad funcional en el hipocampo","_id":"26366136-B435-11E9-9278-68D0E5697425"}],"publication_status":"published","department":[{"_id":"PeJo"},{"_id":"ScienComp"}],"language":[{"iso":"eng"}],"volume":17,"month":"06"},{"user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","author":[{"first_name":"Alois","orcid":"0000-0002-5621-8100","full_name":"Schlögl, Alois","last_name":"Schlögl","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87"}],"file_date_updated":"2026-03-12T10:24:45Z","ec_funded":1,"date_updated":"2026-07-01T06:47:49Z","corr_author":"1","title":"CA3Simu v1.06 (vargas2026v1)","date_published":"2026-03-12T00:00:00Z","has_accepted_license":"1","oa":1,"keyword":["hypocampus","ca3 simulations","modelling"],"tmp":{"name":"GNU General Public License 3.0","short":"GPL 3.0","legal_code_url":"https://www.gnu.org/licenses/gpl-3.0.en.html"},"type":"software","doi":"10.15479/AT-ISTA-21442","fulldoi":"https://doi.org/10.15479/AT-ISTA-21442","month":"03","day":"12","publisher":"Institute of Science and Technology Austria","year":"2026","license":"https://opensource.org/licenses/GPL-3.0","citation":{"chicago":"Schlögl, Alois. “CA3Simu v1.06 (Vargas2026v1).” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21442\">https://doi.org/10.15479/AT-ISTA-21442</a>.","mla":"Schlögl, Alois. <i>CA3Simu v1.06 (Vargas2026v1)</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21442\">10.15479/AT-ISTA-21442</a>.","short":"A. Schlögl, (2026).","ama":"Schlögl A. CA3Simu v1.06 (vargas2026v1). 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21442\">10.15479/AT-ISTA-21442</a>","ista":"Schlögl A. 2026. CA3Simu v1.06 (vargas2026v1), Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21442\">10.15479/AT-ISTA-21442</a>.","ieee":"A. Schlögl, “CA3Simu v1.06 (vargas2026v1).” Institute of Science and Technology Austria, 2026.","apa":"Schlögl, A. (2026). CA3Simu v1.06 (vargas2026v1). 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M., Miles, E., McCarthy, M., Melo Velasco, J. V., Hardmeier, F., GANTAYAT, P., … Pellicciotti, F. (2026). Constraining debris input to Oberaletsch Glacier using ensemble-based Lagrangian modelling. In <i>EGU General Assembly 2026</i>. Vienna, Austria &#38; Virtual: European Geosciences Union. <a href=\"https://doi.org/10.5194/egusphere-egu26-19367\">https://doi.org/10.5194/egusphere-egu26-19367</a>","ieee":"J. M. Muñoz Hermosilla <i>et al.</i>, “Constraining debris input to Oberaletsch Glacier using ensemble-based Lagrangian modelling,” in <i>EGU General Assembly 2026</i>, Vienna, Austria &#38; Virtual, 2026.","ista":"Muñoz Hermosilla JM, Miles E, McCarthy M, Melo Velasco JV, Hardmeier F, GANTAYAT P, Fontrodona-Bach A, Jouvet G, Pellicciotti F. 2026. Constraining debris input to Oberaletsch Glacier using ensemble-based Lagrangian modelling. EGU General Assembly 2026. EGU General Assembly, EGU26-19367.","ama":"Muñoz Hermosilla JM, Miles E, McCarthy M, et al. Constraining debris input to Oberaletsch Glacier using ensemble-based Lagrangian modelling. In: <i>EGU General Assembly 2026</i>. European Geosciences Union; 2026. doi:<a href=\"https://doi.org/10.5194/egusphere-egu26-19367\">10.5194/egusphere-egu26-19367</a>","mla":"Muñoz Hermosilla, José M., et al. “Constraining Debris Input to Oberaletsch Glacier Using Ensemble-Based Lagrangian Modelling.” <i>EGU General Assembly 2026</i>, EGU26-19367, European Geosciences Union, 2026, doi:<a href=\"https://doi.org/10.5194/egusphere-egu26-19367\">10.5194/egusphere-egu26-19367</a>.","short":"J.M. Muñoz Hermosilla, E. Miles, M. McCarthy, J.V. Melo Velasco, F. Hardmeier, P. GANTAYAT, A. Fontrodona-Bach, G. Jouvet, F. Pellicciotti, in:, EGU General Assembly 2026, European Geosciences Union, 2026.","chicago":"Muñoz Hermosilla, José M, Evan Miles, Michael McCarthy, Juan Vicente Melo Velasco, Florian Hardmeier, PRATEEK GANTAYAT, Adrià Fontrodona-Bach, Guillaume Jouvet, and Francesca Pellicciotti. “Constraining Debris Input to Oberaletsch Glacier Using Ensemble-Based Lagrangian Modelling.” In <i>EGU General Assembly 2026</i>. European Geosciences Union, 2026. <a href=\"https://doi.org/10.5194/egusphere-egu26-19367\">https://doi.org/10.5194/egusphere-egu26-19367</a>."},"day":"02","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"fulldoi":"https://doi.org/10.5194/egusphere-egu26-19367","OA_type":"gold","has_accepted_license":"1","date_published":"2026-07-02T00:00:00Z","ddc":["550"],"OA_place":"publisher","date_updated":"2026-07-02T06:42:37Z","file_date_updated":"2026-07-02T06:22:50Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","date_created":"2026-06-22T12:16:50Z","publication_status":"published","language":[{"iso":"eng"}],"department":[{"_id":"FrPe"},{"_id":"GradSch"}],"month":"07","type":"conference_abstract","doi":"10.5194/egusphere-egu26-19367","oa":1,"title":"Constraining debris input to Oberaletsch Glacier using ensemble-based Lagrangian modelling","article_number":"EGU26-19367","conference":{"start_date":"2026-05-03","end_date":"2026-05-08","name":"EGU General Assembly","location":"Vienna, Austria & Virtual"},"corr_author":"1","author":[{"last_name":"Muñoz Hermosilla","id":"e1037a6d-646e-11ef-b402-e0ed9ab0901e","full_name":"Muñoz Hermosilla, José M","orcid":"0000-0002-1990-8508","first_name":"José M"},{"first_name":"Evan","last_name":"Miles","full_name":"Miles, Evan"},{"first_name":"Michael","full_name":"McCarthy, Michael","last_name":"McCarthy","id":"22a2674a-61ce-11ee-94b5-d18813baf16f"},{"last_name":"Melo Velasco","id":"2611dec0-b9c6-11ed-9bea-a81c2b17a549","full_name":"Melo Velasco, Juan Vicente","first_name":"Juan Vicente"},{"last_name":"Hardmeier","full_name":"Hardmeier, Florian","first_name":"Florian"},{"full_name":"GANTAYAT, PRATEEK","last_name":"GANTAYAT","id":"02734268-3e8d-11ef-80a1-cec4a088d004","first_name":"PRATEEK"},{"full_name":"Fontrodona-Bach, Adrià","last_name":"Fontrodona-Bach","id":"f06891fd-9f42-11ee-8632-a20971c43046","first_name":"Adrià"},{"first_name":"Guillaume","last_name":"Jouvet","full_name":"Jouvet, Guillaume"},{"first_name":"Francesca","orcid":"0000-0002-5554-8087","full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70"}],"publication":"EGU General Assembly 2026"},{"ddc":["000"],"OA_type":"hybrid","date_published":"2026-07-03T00:00:00Z","has_accepted_license":"1","PlanS_conform":"1","article_type":"original","fulldoi":"https://doi.org/10.1145/3811339","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"OA_place":"publisher","date_updated":"2026-07-06T06:14:18Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"text":"We revisit the computation of 3D generalized winding numbers, a useful measure for inside-outside classification on triangle meshes with gaps, self-intersections, and open boundaries. At the core of our new method is an analytical reduction of the surface integral that defines the winding number, resulting in a single ray-mesh intersection test and an elementary sum over boundary edges per evaluation. This construction is orders of magnitude more efficient than the state of the art in practice, which we show in an extensive performance benchmark. Conveniently, the method also reduces to the best-available asymptotic complexity in the worst case, and it introduces no approximations apart from floating-point errors. Our algorithm is conceptually simple to understand, straightforward to implement and debug, and it works reliably even on extremely noisy and corrupt input geometry.","lang":"eng"}],"file_date_updated":"2026-07-06T06:13:12Z","issue":"4","file":[{"date_created":"2026-07-06T06:13:12Z","file_size":5212838,"file_name":"2026_TransactionsGraphics_Xie.pdf","success":1,"file_id":"22249","creator":"dernst","content_type":"application/pdf","date_updated":"2026-07-06T06:13:12Z","access_level":"open_access","checksum":"7e36e69f377b680a893e65b620b43813","relation":"main_file"}],"intvolume":"        45","_id":"22241","researchdata_availability":"no","status":"public","oa_version":"Published Version","day":"03","das_tickbox":"0","year":"2026","citation":{"chicago":"Xie, Peiyuan, Christian Hafner, and Chris Wojtan. “Fast and Exact Winding Numbers for Triangle Meshes.” <i>ACM Transactions on Graphics</i>. Association for Computing Machinery, 2026. <a href=\"https://doi.org/10.1145/3811339\">https://doi.org/10.1145/3811339</a>.","short":"P. Xie, C. Hafner, C. Wojtan, ACM Transactions on Graphics 45 (2026).","mla":"Xie, Peiyuan, et al. “Fast and Exact Winding Numbers for Triangle Meshes.” <i>ACM Transactions on Graphics</i>, vol. 45, no. 4, 41, Association for Computing Machinery, 2026, doi:<a href=\"https://doi.org/10.1145/3811339\">10.1145/3811339</a>.","ista":"Xie P, Hafner C, Wojtan C. 2026. Fast and exact winding numbers for triangle meshes. ACM Transactions on Graphics. 45(4), 41.","ama":"Xie P, Hafner C, Wojtan C. Fast and exact winding numbers for triangle meshes. <i>ACM Transactions on Graphics</i>. 2026;45(4). doi:<a href=\"https://doi.org/10.1145/3811339\">10.1145/3811339</a>","apa":"Xie, P., Hafner, C., &#38; Wojtan, C. (2026). Fast and exact winding numbers for triangle meshes. <i>ACM Transactions on Graphics</i>. Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3811339\">https://doi.org/10.1145/3811339</a>","ieee":"P. Xie, C. Hafner, and C. Wojtan, “Fast and exact winding numbers for triangle meshes,” <i>ACM Transactions on Graphics</i>, vol. 45, no. 4. Association for Computing Machinery, 2026."},"acknowledgement":"We thank Sadashige Ishida and Ryusuke Sugimoto for their insightful discussions and proofreading and other members of the ISTA\r\nVisual Computing Group for their general feedback. This project was\r\nfunded in part by the European Research Council (ERC Consolidator\r\nGrant 101045083 CoDiNA).","publisher":"Association for Computing Machinery","publication_identifier":{"eissn":["1557-7368"],"issn":["0730-0301"]},"oa":1,"title":"Fast and exact winding numbers for triangle meshes","doi":"10.1145/3811339","type":"journal_article","article_number":"41","corr_author":"1","scopus_import":"1","publication":"ACM Transactions on Graphics","author":[{"id":"488e236c-6bad-11f0-9831-859175c78e8a","last_name":"Xie","full_name":"Xie, Peiyuan","first_name":"Peiyuan"},{"last_name":"Hafner","id":"400429CC-F248-11E8-B48F-1D18A9856A87","full_name":"Hafner, Christian","first_name":"Christian"},{"first_name":"Christopher J","orcid":"0000-0001-6646-5546","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","last_name":"Wojtan","full_name":"Wojtan, Christopher J"}],"supplementarymaterial":"no","date_created":"2026-07-03T21:03:48Z","article_processing_charge":"Yes (via OA deal)","project":[{"_id":"34bc2376-11ca-11ed-8bc3-9a3b3961a088","name":"Computational Discovery of Numerical Algorithms for Animation and Simulation of Natural Phenomena","grant_number":"101045083"}],"quality_controlled":"1","department":[{"_id":"GradSch"},{"_id":"ChWo"}],"volume":45,"language":[{"iso":"eng"}],"publication_status":"published","month":"07"},{"file_date_updated":"2026-07-06T07:24:43Z","abstract":[{"lang":"eng","text":"Many living and artificial systems improve their fitness or performance by adapting to changing environments or diverse training data. However, it remains unclear how environmental variation shapes adaptation, what is learned, and when memory of past conditions is retained. Here we show how cyclic environmental change can produce robust memory. Using a model athermal disordered solid trained by inverse design to attain target elastic properties over a prescribed range, we find that the system evolves toward a marginally absorbing manifold (MAM), meaning that training is reversible within the training range but not beyond it, which encodes a memory of that range. We further propose a general mechanism for MAM formation and memory encoding based on discontinuities in the gradient of the trained quantity. These results provide a simple, broadly applicable physical framework for how adaptive systems learn under changing environments and retain memory of past conditions."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-07-06T07:28:45Z","DOAJ_listed":"1","OA_place":"publisher","tmp":{"image":"/images/cc_by.png","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"fulldoi":"https://doi.org/10.1103/48k2-cw3b","article_type":"original","PlanS_conform":"1","date_published":"2026-06-18T00:00:00Z","has_accepted_license":"1","OA_type":"gold","ddc":["570"],"publisher":"American Physical Society","acknowledgement":"We thank Nathan Keim, Aayush Desai, Nicholas Barton,\r\nand Gašper Tkacik for important and stimulating discussions. ˇ\r\nThe work was funded by the Institute of Science and Technology Austria.","year":"2026","citation":{"ieee":"M. Zu and C. P. Goodrich, “Learning by Training: Emergent physical memory from cyclically tuning disordered sphere packings,” <i>PRX Life</i>, vol. 4, no. 2. American Physical Society, 2026.","apa":"Zu, M., &#38; Goodrich, C. P. (2026). Learning by Training: Emergent physical memory from cyclically tuning disordered sphere packings. <i>PRX Life</i>. American Physical Society. <a href=\"https://doi.org/10.1103/48k2-cw3b\">https://doi.org/10.1103/48k2-cw3b</a>","ista":"Zu M, Goodrich CP. 2026. Learning by Training: Emergent physical memory from cyclically tuning disordered sphere packings. PRX Life. 4(2), 023029.","ama":"Zu M, Goodrich CP. Learning by Training: Emergent physical memory from cyclically tuning disordered sphere packings. <i>PRX Life</i>. 2026;4(2). doi:<a href=\"https://doi.org/10.1103/48k2-cw3b\">10.1103/48k2-cw3b</a>","short":"M. Zu, C.P. Goodrich, PRX Life 4 (2026).","mla":"Zu, Mengjie, and Carl Peter Goodrich. “Learning by Training: Emergent Physical Memory from Cyclically Tuning Disordered Sphere Packings.” <i>PRX Life</i>, vol. 4, no. 2, 023029, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/48k2-cw3b\">10.1103/48k2-cw3b</a>.","chicago":"Zu, Mengjie, and Carl Peter Goodrich. “Learning by Training: Emergent Physical Memory from Cyclically Tuning Disordered Sphere Packings.” <i>PRX Life</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/48k2-cw3b\">https://doi.org/10.1103/48k2-cw3b</a>."},"das_tickbox":"1","day":"18","oa_version":"Published Version","status":"public","_id":"22248","researchdata_availability":"upon request","intvolume":"         4","file":[{"file_id":"22251","success":1,"file_name":"2026_PRXLife_Zu.pdf","date_created":"2026-07-06T07:24:43Z","file_size":2758728,"relation":"main_file","access_level":"open_access","checksum":"e2d13c30bf9c036951fd2ba3455cf72a","date_updated":"2026-07-06T07:24:43Z","content_type":"application/pdf","creator":"dernst"}],"issue":"2","dataavailabilitystatement":"The data that support the findings of this article are not\r\npublicly available. The data are available from the authors\r\nupon reasonable request.","author":[{"first_name":"Mengjie","full_name":"Zu, Mengjie","id":"26dd9e7c-e86a-11eb-a854-82ac731c9ae2","last_name":"Zu"},{"full_name":"Goodrich, Carl Peter","last_name":"Goodrich","id":"EB352CD2-F68A-11E9-89C5-A432E6697425","first_name":"Carl Peter","orcid":"0000-0002-1307-5074"}],"publication":"PRX Life","scopus_import":"1","corr_author":"1","article_number":"023029","type":"journal_article","doi":"10.1103/48k2-cw3b","title":"Learning by Training: Emergent physical memory from cyclically tuning disordered sphere packings","oa":1,"publication_identifier":{"eissn":["2835-8279"]},"month":"06","publication_status":"published","language":[{"iso":"eng"}],"volume":4,"department":[{"_id":"CaGo"}],"quality_controlled":"1","article_processing_charge":"Yes","date_created":"2026-07-05T22:01:37Z","supplementarymaterial":"no"}]