[{"department":[{"_id":"RySh"}],"isi":1,"has_accepted_license":"1","day":"21","ddc":["570"],"title":"Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice","abstract":[{"text":"Alzheimer’s disease (AD) is characterized by a reorganization of brain activity determining network hyperexcitability and loss of synaptic plasticity. Precisely, a dysfunction in metabotropic GABAB receptor signalling through G protein-gated inwardly rectifying K+ (GIRK or Kir3) channels on the hippocampus has been postulated. Thus, we determined the impact of amyloid-β (Aβ) pathology in GIRK channel density, subcellular distribution, and its association with GABAB receptors in hippocampal CA1 pyramidal neurons from the APP/PS1 mouse model using quantitative SDS-digested freeze-fracture replica labelling (SDS-FRL) and proximity ligation in situ assay (P-LISA). In wild type mice, single SDS-FRL detection revealed a similar dendritic gradient for GIRK1 and GIRK2 in CA1 pyramidal cells, with higher densities in spines, and GIRK3 showed a lower and uniform distribution. Double SDS-FRL showed a co-clustering of GIRK2 and GIRK1 in post- and presynaptic compartments, but not for GIRK2 and GIRK3. Likewise, double GABAB1 and GIRK2 SDS-FRL detection displayed a high degree of co-clustering in nanodomains (40–50 nm) mostly in spines and axon terminals. In APP/PS1 mice, the density of GIRK2 and GIRK1, but not for GIRK3, was significantly reduced along the neuronal surface of CA1 pyramidal cells and in axon terminals contacting them. Importantly, GABAB1 and GIRK2 co-clustering was not present in APP/PS1 mice. Similarly, P-LISA experiments revealed a significant reduction in GABAB1 and GIRK2 interaction on the hippocampus of this animal model. Overall, our results provide compelling evidence showing a significant reduction on the cell surface density of pre- and postsynaptic GIRK1 and GIRK2, but not GIRK3, and a decline in GABAB receptors and GIRK2 channels co-clustering in hippocampal pyramidal neurons from APP/PS1 mice, thus suggesting that a disruption in the GABAB receptor–GIRK channel membrane assembly causes dysregulation in the GABAB signalling via GIRK channels in this AD animal model.","lang":"eng"}],"intvolume":"        14","date_updated":"2025-06-11T13:40:00Z","article_number":"136","oa_version":"Published Version","author":[{"last_name":"Martín-Belmonte","full_name":"Martín-Belmonte, Alejandro","first_name":"Alejandro"},{"first_name":"Carolina","last_name":"Aguado","full_name":"Aguado, Carolina"},{"first_name":"Rocío","full_name":"Alfaro-Ruiz, Rocío","last_name":"Alfaro-Ruiz"},{"first_name":"Ana Esther","full_name":"Moreno-Martínez, Ana Esther","last_name":"Moreno-Martínez"},{"full_name":"de la Ossa, Luis","last_name":"de la Ossa","first_name":"Luis"},{"last_name":"Aso","full_name":"Aso, Ester","first_name":"Ester"},{"first_name":"Laura","full_name":"Gómez-Acero, Laura","last_name":"Gómez-Acero"},{"last_name":"Shigemoto","full_name":"Shigemoto, Ryuichi","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi","orcid":"0000-0001-8761-9444"},{"full_name":"Fukazawa, Yugo","last_name":"Fukazawa","first_name":"Yugo"},{"first_name":"Francisco","last_name":"Ciruela","full_name":"Ciruela, Francisco"},{"first_name":"Rafael","last_name":"Luján","full_name":"Luján, Rafael"}],"article_processing_charge":"No","acknowledgement":"We thank Ms. Diane Latawiec for the English revision of the manuscript. Funding sources were the Spanish Ministerio de Economía y Competitividad, Junta de Comunidades de Castilla-La Mancha (Spain), and Life Science Innovation Center at University of Fukui. We thank Centres de Recerca de Catalunya (CERCA) Programme/Generalitat de Catalunya for IDIBELL institutional support. We thank Hitoshi Takagi and Takako Maegawa at the University of Fukui for their technical assistance on SDS-FRL experiments.\r\nThis work was supported by grants from the Spanish Ministerio de Economía y Competitividad (BFU2015-63769-R, RTI2018-095812-B-I00, and PID2021-125875OB-I00) and Junta de Comunidades de Castilla-La Mancha (SBPLY/17/180501/000229 and SBPLY/21/180501/000064) to RL, Life Science Innovation Center at University of Fukui and JSPS KAKENHI (Grant Numbers 16H04662, 19H03323, and 20H05058) to YF, and Margarita Salas fellowship from Ministerio de Universidades and Universidad de Castilla-La Mancha to AMB.","file_date_updated":"2023-01-27T07:53:18Z","status":"public","date_created":"2023-01-16T09:45:51Z","publication":"Alzheimer's Research & Therapy","publication_identifier":{"issn":["1758-9193"]},"_id":"12212","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"09","scopus_import":"1","pmid":1,"type":"journal_article","volume":14,"citation":{"short":"A. Martín-Belmonte, C. Aguado, R. Alfaro-Ruiz, A.E. Moreno-Martínez, L. de la Ossa, E. Aso, L. Gómez-Acero, R. Shigemoto, Y. Fukazawa, F. Ciruela, R. Luján, Alzheimer’s Research &#38; Therapy 14 (2022).","mla":"Martín-Belmonte, Alejandro, et al. “Nanoscale Alterations in GABAB Receptors and GIRK Channel Organization on the Hippocampus of APP/PS1 Mice.” <i>Alzheimer’s Research &#38; Therapy</i>, vol. 14, 136, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1186/s13195-022-01078-5\">10.1186/s13195-022-01078-5</a>.","ista":"Martín-Belmonte A, Aguado C, Alfaro-Ruiz R, Moreno-Martínez AE, de la Ossa L, Aso E, Gómez-Acero L, Shigemoto R, Fukazawa Y, Ciruela F, Luján R. 2022. Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice. Alzheimer’s Research &#38; Therapy. 14, 136.","chicago":"Martín-Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro-Ruiz, Ana Esther Moreno-Martínez, Luis de la Ossa, Ester Aso, Laura Gómez-Acero, et al. “Nanoscale Alterations in GABAB Receptors and GIRK Channel Organization on the Hippocampus of APP/PS1 Mice.” <i>Alzheimer’s Research &#38; Therapy</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1186/s13195-022-01078-5\">https://doi.org/10.1186/s13195-022-01078-5</a>.","ieee":"A. Martín-Belmonte <i>et al.</i>, “Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice,” <i>Alzheimer’s Research &#38; Therapy</i>, vol. 14. Springer Nature, 2022.","ama":"Martín-Belmonte A, Aguado C, Alfaro-Ruiz R, et al. Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice. <i>Alzheimer’s Research &#38; Therapy</i>. 2022;14. doi:<a href=\"https://doi.org/10.1186/s13195-022-01078-5\">10.1186/s13195-022-01078-5</a>","apa":"Martín-Belmonte, A., Aguado, C., Alfaro-Ruiz, R., Moreno-Martínez, A. E., de la Ossa, L., Aso, E., … Luján, R. (2022). Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice. <i>Alzheimer’s Research &#38; Therapy</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s13195-022-01078-5\">https://doi.org/10.1186/s13195-022-01078-5</a>"},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Cognitive Neuroscience","Neurology (clinical)","Neurology"],"article_type":"original","date_published":"2022-09-21T00:00:00Z","language":[{"iso":"eng"}],"publisher":"Springer Nature","doi":"10.1186/s13195-022-01078-5","oa":1,"file":[{"checksum":"88e49715ad6a1abf0fdb27efd65368dc","access_level":"open_access","file_name":"2022_AlzheimersResearch_MartinBelmont.pdf","file_id":"12413","file_size":11013325,"date_updated":"2023-01-27T07:53:18Z","content_type":"application/pdf","date_created":"2023-01-27T07:53:18Z","success":1,"creator":"dernst","relation":"main_file"}],"year":"2022","quality_controlled":"1","external_id":{"isi":["000857985500001"],"pmid":["36131327"]}},{"year":"2022","quality_controlled":"1","external_id":{"isi":["000852381200003"]},"keyword":["Condensed Matter Physics","Electronic","Optical and Magnetic Materials"],"article_type":"original","doi":"10.1038/s41535-022-00496-w","language":[{"iso":"eng"}],"date_published":"2022-09-10T00:00:00Z","publisher":"Springer Nature","oa":1,"file":[{"date_created":"2023-01-27T07:59:27Z","creator":"dernst","relation":"main_file","success":1,"file_id":"12414","checksum":"d93b477b5b95c0d1b8f9fef90a81f565","access_level":"open_access","file_name":"2022_NPJ_Paerschke.pdf","date_updated":"2023-01-27T07:59:27Z","content_type":"application/pdf","file_size":1852598}],"type":"journal_article","volume":7,"corr_author":"1","citation":{"ieee":"E. Paerschke, W.-C. Chen, R. Ray, and C.-C. Chen, “Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain,” <i>npj Quantum Materials</i>, vol. 7. Springer Nature, 2022.","apa":"Paerschke, E., Chen, W.-C., Ray, R., &#38; Chen, C.-C. (2022). Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain. <i>Npj Quantum Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41535-022-00496-w\">https://doi.org/10.1038/s41535-022-00496-w</a>","ama":"Paerschke E, Chen W-C, Ray R, Chen C-C. Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain. <i>npj Quantum Materials</i>. 2022;7. doi:<a href=\"https://doi.org/10.1038/s41535-022-00496-w\">10.1038/s41535-022-00496-w</a>","ista":"Paerschke E, Chen W-C, Ray R, Chen C-C. 2022. Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain. npj Quantum Materials. 7, 90.","mla":"Paerschke, Ekaterina, et al. “Evolution of Electronic and Magnetic Properties of Sr₂IrO₄ under Strain.” <i>Npj Quantum Materials</i>, vol. 7, 90, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41535-022-00496-w\">10.1038/s41535-022-00496-w</a>.","chicago":"Paerschke, Ekaterina, Wei-Chih Chen, Rajyavardhan Ray, and Cheng-Chien Chen. “Evolution of Electronic and Magnetic Properties of Sr₂IrO₄ under Strain.” <i>Npj Quantum Materials</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41535-022-00496-w\">https://doi.org/10.1038/s41535-022-00496-w</a>.","short":"E. Paerschke, W.-C. Chen, R. Ray, C.-C. Chen, Npj Quantum Materials 7 (2022)."},"publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","_id":"12213","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"09","scopus_import":"1","publication":"npj Quantum Materials","related_material":{"link":[{"url":"https://doi.org/10.1038/s41535-022-00510-1","relation":"erratum"}]},"publication_identifier":{"eissn":["2397-4648"]},"ec_funded":1,"article_processing_charge":"No","acknowledgement":"E.M.P. thanks Eugenio Paris, Thorsten Schmitt, Krzysztof Wohlfeld, and other coauthors for an inspiring previous collaboration23, and is grateful to Gang Cao, Ambrose Seo, and Jungho Kim for insightful discussions. R.R. acknowledges helpful discussion with Sanjeev Kumar and Manuel Richter. This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 754411. C.C.C. acknowledges support from the U.S. National Science Foundation Award No. DMR-2142801.","file_date_updated":"2023-01-27T07:59:27Z","status":"public","date_created":"2023-01-16T09:46:01Z","abstract":[{"lang":"eng","text":"Motivated by properties-controlling potential of the strain, we investigate strain dependence of structure, electronic, and magnetic properties of Sr2IrO4 using complementary theoretical tools: ab-initio calculations, analytical approaches (rigid octahedra picture, Slater-Koster integrals), and extended t−J model. We find that strain affects both Ir-Ir distance and Ir-O-Ir angle, and the rigid octahedra picture is not relevant. Second, we find fundamentally different behavior for compressive and tensile strain. One remarkable feature is the formation of two subsets of bond- and orbital-dependent carriers, a compass-like model, under compression. This originates from the strain-induced renormalization of the Ir-O-Ir superexchange and O on-site energy. We also show that under compressive (tensile) strain, Fermi surface becomes highly dispersive (relatively flat). Already at a tensile strain of 1.5%, we observe spectral weight redistribution, with the low-energy band acquiring almost purely singlet character. These results can be directly compared with future experiments."}],"intvolume":"         7","date_updated":"2025-04-14T07:44:00Z","oa_version":"Published Version","article_number":"90","author":[{"full_name":"Paerschke, Ekaterina","last_name":"Paerschke","orcid":"0000-0003-0853-8182","id":"8275014E-6063-11E9-9B7F-6338E6697425","first_name":"Ekaterina"},{"first_name":"Wei-Chih","last_name":"Chen","full_name":"Chen, Wei-Chih"},{"full_name":"Ray, Rajyavardhan","last_name":"Ray","first_name":"Rajyavardhan"},{"first_name":"Cheng-Chien","last_name":"Chen","full_name":"Chen, Cheng-Chien"}],"project":[{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"754411"}],"department":[{"_id":"MiLe"}],"isi":1,"has_accepted_license":"1","day":"10","ddc":["530"],"title":"Evolution of electronic and magnetic properties of Sr₂IrO₄ under strain"},{"author":[{"last_name":"Gehér","full_name":"Gehér, György Pál","first_name":"György Pál"},{"first_name":"Tamás","full_name":"Titkos, Tamás","last_name":"Titkos"},{"full_name":"Virosztek, Daniel","last_name":"Virosztek","orcid":"0000-0003-1109-5511","first_name":"Daniel","id":"48DB45DA-F248-11E8-B48F-1D18A9856A87"}],"intvolume":"       106","date_updated":"2025-04-14T07:50:40Z","oa_version":"Preprint","abstract":[{"lang":"eng","text":"Motivated by Kloeckner’s result on the isometry group of the quadratic Wasserstein space W2(Rn), we describe the isometry group Isom(Wp(E)) for all parameters 0 < p < ∞ and for all separable real Hilbert spaces E. In particular, we show that Wp(X) is isometrically rigid for all Polish space X whenever 0 < p < 1. This is a consequence of our more general result: we prove that W1(X) is isometrically rigid if X is a complete separable metric space that satisfies the strict triangle inequality. Furthermore, we show that this latter rigidity result does not generalise to parameters p > 1, by solving Kloeckner’s problem affirmatively on the existence of mass-splitting isometries. "}],"title":"The isometry group of Wasserstein spaces: The Hilbertian case","day":"18","isi":1,"project":[{"name":"Geometric study of Wasserstein spaces and free probability","call_identifier":"H2020","grant_number":"846294","_id":"26A455A6-B435-11E9-9278-68D0E5697425"}],"department":[{"_id":"LaEr"}],"ec_funded":1,"publication_identifier":{"eissn":["1469-7750"],"issn":["0024-6107"]},"publication":"Journal of the London Mathematical Society","status":"public","date_created":"2023-01-16T09:46:13Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2102.02037"}],"acknowledgement":"Geher was supported by the Leverhulme Trust Early Career Fellowship (ECF-2018-125), and also by the Hungarian National Research, Development and Innovation Office - NKFIH (grant no. K115383 and K134944).\r\nTitkos was supported by the Hungarian National Research, Development and Innovation Office - NKFIH (grant no. PD128374, grant no. K115383 and K134944), by the J´anos Bolyai Research Scholarship of the Hungarian Academy of Sciences, and by the UNKP-20-5-BGE-1 New National Excellence Program of the ´Ministry of Innovation and Technology.\r\nVirosztek was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 846294, by the Momentum program of the Hungarian Academy of Sciences under grant agreement no. LP2021-15/2021, and partially supported by the Hungarian National Research, Development and Innovation Office - NKFIH (grants no. K124152 and no. KH129601). ","article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"ama":"Gehér GP, Titkos T, Virosztek D. The isometry group of Wasserstein spaces: The Hilbertian case. <i>Journal of the London Mathematical Society</i>. 2022;106(4):3865-3894. doi:<a href=\"https://doi.org/10.1112/jlms.12676\">10.1112/jlms.12676</a>","apa":"Gehér, G. P., Titkos, T., &#38; Virosztek, D. (2022). The isometry group of Wasserstein spaces: The Hilbertian case. <i>Journal of the London Mathematical Society</i>. Wiley. <a href=\"https://doi.org/10.1112/jlms.12676\">https://doi.org/10.1112/jlms.12676</a>","ieee":"G. P. Gehér, T. Titkos, and D. Virosztek, “The isometry group of Wasserstein spaces: The Hilbertian case,” <i>Journal of the London Mathematical Society</i>, vol. 106, no. 4. Wiley, pp. 3865–3894, 2022.","mla":"Gehér, György Pál, et al. “The Isometry Group of Wasserstein Spaces: The Hilbertian Case.” <i>Journal of the London Mathematical Society</i>, vol. 106, no. 4, Wiley, 2022, pp. 3865–94, doi:<a href=\"https://doi.org/10.1112/jlms.12676\">10.1112/jlms.12676</a>.","chicago":"Gehér, György Pál, Tamás Titkos, and Daniel Virosztek. “The Isometry Group of Wasserstein Spaces: The Hilbertian Case.” <i>Journal of the London Mathematical Society</i>. Wiley, 2022. <a href=\"https://doi.org/10.1112/jlms.12676\">https://doi.org/10.1112/jlms.12676</a>.","ista":"Gehér GP, Titkos T, Virosztek D. 2022. The isometry group of Wasserstein spaces: The Hilbertian case. Journal of the London Mathematical Society. 106(4), 3865–3894.","short":"G.P. Gehér, T. Titkos, D. Virosztek, Journal of the London Mathematical Society 106 (2022) 3865–3894."},"publication_status":"published","volume":106,"type":"journal_article","arxiv":1,"scopus_import":"1","month":"09","_id":"12214","external_id":{"isi":["000854878500001"],"arxiv":["2102.02037"]},"page":"3865-3894","year":"2022","quality_controlled":"1","oa":1,"issue":"4","doi":"10.1112/jlms.12676","publisher":"Wiley","date_published":"2022-09-18T00:00:00Z","language":[{"iso":"eng"}],"article_type":"original","keyword":["General Mathematics"]},{"_id":"12216","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"month":"12","scopus_import":"1","volume":654,"type":"journal_article","corr_author":"1","publication_status":"published","citation":{"ieee":"E. A. Carlen and H. Zhang, “Monotonicity versions of Epstein’s concavity theorem and related inequalities,” <i>Linear Algebra and its Applications</i>, vol. 654. Elsevier, pp. 289–310, 2022.","apa":"Carlen, E. A., &#38; Zhang, H. (2022). Monotonicity versions of Epstein’s concavity theorem and related inequalities. <i>Linear Algebra and Its Applications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.laa.2022.09.001\">https://doi.org/10.1016/j.laa.2022.09.001</a>","ama":"Carlen EA, Zhang H. Monotonicity versions of Epstein’s concavity theorem and related inequalities. <i>Linear Algebra and its Applications</i>. 2022;654:289-310. doi:<a href=\"https://doi.org/10.1016/j.laa.2022.09.001\">10.1016/j.laa.2022.09.001</a>","chicago":"Carlen, Eric A., and Haonan Zhang. “Monotonicity Versions of Epstein’s Concavity Theorem and Related Inequalities.” <i>Linear Algebra and Its Applications</i>. Elsevier, 2022. <a href=\"https://doi.org/10.1016/j.laa.2022.09.001\">https://doi.org/10.1016/j.laa.2022.09.001</a>.","ista":"Carlen EA, Zhang H. 2022. Monotonicity versions of Epstein’s concavity theorem and related inequalities. Linear Algebra and its Applications. 654, 289–310.","mla":"Carlen, Eric A., and Haonan Zhang. “Monotonicity Versions of Epstein’s Concavity Theorem and Related Inequalities.” <i>Linear Algebra and Its Applications</i>, vol. 654, Elsevier, 2022, pp. 289–310, doi:<a href=\"https://doi.org/10.1016/j.laa.2022.09.001\">10.1016/j.laa.2022.09.001</a>.","short":"E.A. Carlen, H. Zhang, Linear Algebra and Its Applications 654 (2022) 289–310."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","keyword":["Discrete Mathematics and Combinatorics","Geometry and Topology","Numerical Analysis","Algebra and Number Theory"],"article_type":"original","language":[{"iso":"eng"}],"doi":"10.1016/j.laa.2022.09.001","publisher":"Elsevier","date_published":"2022-12-01T00:00:00Z","file":[{"file_size":441184,"content_type":"application/pdf","date_updated":"2023-01-27T08:08:39Z","file_name":"2022_LinearAlgebra_Carlen.pdf","access_level":"open_access","checksum":"cf3cb7e7e34baa967849f01d8f0c1ae4","file_id":"12415","success":1,"creator":"dernst","relation":"main_file","date_created":"2023-01-27T08:08:39Z"}],"oa":1,"quality_controlled":"1","year":"2022","page":"289-310","external_id":{"isi":["000860689600014"]},"department":[{"_id":"JaMa"}],"project":[{"name":"Curvature-dimension in noncommutative analysis","grant_number":"M03337","_id":"eb958bca-77a9-11ec-83b8-c565cb50d8d6"}],"has_accepted_license":"1","isi":1,"ddc":["510"],"day":"01","title":"Monotonicity versions of Epstein's concavity theorem and related inequalities","abstract":[{"text":"Many trace inequalities can be expressed either as concavity/convexity theorems or as monotonicity theorems. A classic example is the joint convexity of the quantum relative entropy which is equivalent to the Data Processing Inequality. The latter says that quantum operations can never increase the relative entropy. The monotonicity versions often have many advantages, and often have direct physical application, as in the example just mentioned. Moreover, the monotonicity results are often valid for a larger class of maps than, say, quantum operations (which are completely positive). In this paper we prove several new monotonicity results, the first of which is a monotonicity theorem that has as a simple corollary a celebrated concavity theorem of Epstein. Our starting points are the monotonicity versions of the Lieb Concavity and the Lieb Convexity Theorems. We also give two new proofs of these in their general forms using interpolation. We then prove our new monotonicity theorems by several duality arguments.","lang":"eng"}],"oa_version":"Published Version","intvolume":"       654","date_updated":"2025-04-14T13:05:27Z","author":[{"last_name":"Carlen","full_name":"Carlen, Eric A.","first_name":"Eric A."},{"full_name":"Zhang, Haonan","last_name":"Zhang","first_name":"Haonan","id":"D8F41E38-9E66-11E9-A9E2-65C2E5697425"}],"article_processing_charge":"Yes (via OA deal)","acknowledgement":"Work partially supported by the Lise Meitner fellowship, Austrian Science Fund (FWF) M3337.","date_created":"2023-01-16T09:46:38Z","file_date_updated":"2023-01-27T08:08:39Z","status":"public","publication":"Linear Algebra and its Applications","publication_identifier":{"issn":["0024-3795"]}},{"quality_controlled":"1","year":"2022","external_id":{"pmid":["36064947"],"isi":["000850348400025"]},"keyword":["General Physics and Astronomy","General Biochemistry","Genetics and Molecular Biology","General Chemistry","Multidisciplinary"],"article_type":"original","publisher":"Springer Nature","doi":"10.1038/s41467-022-32806-y","language":[{"iso":"eng"}],"date_published":"2022-09-05T00:00:00Z","file":[{"date_created":"2023-01-27T08:14:48Z","success":1,"creator":"dernst","relation":"main_file","checksum":"295261b5172274fd5b8f85a6a6058828","access_level":"open_access","file_name":"2022_NatureCommunications_Randriamanantsoa.pdf","file_id":"12416","file_size":22645149,"date_updated":"2023-01-27T08:14:48Z","content_type":"application/pdf"}],"oa":1,"volume":13,"type":"journal_article","publication_status":"published","citation":{"ieee":"S. Randriamanantsoa <i>et al.</i>, “Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","apa":"Randriamanantsoa, S., Papargyriou, A., Maurer, H. C., Peschke, K., Schuster, M., Zecchin, G., … Bausch, A. R. (2022). Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-32806-y\">https://doi.org/10.1038/s41467-022-32806-y</a>","ama":"Randriamanantsoa S, Papargyriou A, Maurer HC, et al. Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-32806-y\">10.1038/s41467-022-32806-y</a>","short":"S. Randriamanantsoa, A. Papargyriou, H.C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, R. Öllinger, D. Saur, C. Scheel, R. Rad, E.B. Hannezo, M. Reichert, A.R. Bausch, Nature Communications 13 (2022).","ista":"Randriamanantsoa S, Papargyriou A, Maurer HC, Peschke K, Schuster M, Zecchin G, Steiger K, Öllinger R, Saur D, Scheel C, Rad R, Hannezo EB, Reichert M, Bausch AR. 2022. Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. Nature Communications. 13, 5219.","chicago":"Randriamanantsoa, S., A. Papargyriou, H. C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, et al. “Spatiotemporal Dynamics of Self-Organized Branching in Pancreas-Derived Organoids.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-32806-y\">https://doi.org/10.1038/s41467-022-32806-y</a>.","mla":"Randriamanantsoa, S., et al. “Spatiotemporal Dynamics of Self-Organized Branching in Pancreas-Derived Organoids.” <i>Nature Communications</i>, vol. 13, 5219, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-32806-y\">10.1038/s41467-022-32806-y</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12217","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"pmid":1,"scopus_import":"1","month":"09","related_material":{"record":[{"id":"13068","relation":"research_data","status":"public"}]},"publication":"Nature Communications","publication_identifier":{"issn":["2041-1723"]},"ec_funded":1,"article_processing_charge":"No","acknowledgement":"A.R.B. acknowledges the financial support of the European Research Council (ERC) through the funding of the grant Principles of Integrin Mechanics and Adhesion (PoINT) and the German Research Foundation (DFG, SFB 1032, project ID 201269156). E.H. was supported by the European Union (European Research Council Starting Grant 851288). D.S., M.R., and R.R. acknowledge the support by the German Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project S01, project ID 329628492). C.S. and M.R. acknowledge the support by the German Research Foundation (DFG, SFB1321 Modeling and Targeting Pancreatic Cancer, Project 12, project ID 329628492). M.R. was supported by the German Research Foundation (DFG RE 3723/4-1). A.P. and M.R. were supported by the German Cancer Aid (Max-Eder Program 111273 and 70114328).\r\nOpen Access funding enabled and organized by Projekt DEAL.","date_created":"2023-01-16T09:46:53Z","status":"public","file_date_updated":"2023-01-27T08:14:48Z","abstract":[{"text":"The development dynamics and self-organization of glandular branched epithelia is of utmost importance for our understanding of diverse processes ranging from normal tissue growth to the growth of cancerous tissues. Using single primary murine pancreatic ductal adenocarcinoma (PDAC) cells embedded in a collagen matrix and adapted media supplementation, we generate organoids that self-organize into highly branched structures displaying a seamless lumen connecting terminal end buds, replicating in vivo PDAC architecture. We identify distinct morphogenesis phases, each characterized by a unique pattern of cell invasion, matrix deformation, protein expression, and respective molecular dependencies. We propose a minimal theoretical model of a branching and proliferating tissue, capturing the dynamics of the first phases. Observing the interaction of morphogenesis, mechanical environment and gene expression in vitro sets a benchmark for the understanding of self-organization processes governing complex organoid structure formation processes and branching morphogenesis.","lang":"eng"}],"oa_version":"Published Version","article_number":"5219","intvolume":"        13","date_updated":"2025-06-11T13:53:55Z","author":[{"first_name":"S.","full_name":"Randriamanantsoa, S.","last_name":"Randriamanantsoa"},{"first_name":"A.","full_name":"Papargyriou, A.","last_name":"Papargyriou"},{"first_name":"H. C.","full_name":"Maurer, H. C.","last_name":"Maurer"},{"full_name":"Peschke, K.","last_name":"Peschke","first_name":"K."},{"first_name":"M.","last_name":"Schuster","full_name":"Schuster, M."},{"full_name":"Zecchin, G.","last_name":"Zecchin","first_name":"G."},{"first_name":"K.","full_name":"Steiger, K.","last_name":"Steiger"},{"first_name":"R.","full_name":"Öllinger, R.","last_name":"Öllinger"},{"first_name":"D.","last_name":"Saur","full_name":"Saur, D."},{"last_name":"Scheel","full_name":"Scheel, C.","first_name":"C."},{"last_name":"Rad","full_name":"Rad, R.","first_name":"R."},{"full_name":"Hannezo, Edouard B","last_name":"Hannezo","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B"},{"first_name":"M.","last_name":"Reichert","full_name":"Reichert, M."},{"full_name":"Bausch, A. R.","last_name":"Bausch","first_name":"A. R."}],"department":[{"_id":"EdHa"}],"project":[{"name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","grant_number":"851288"}],"isi":1,"has_accepted_license":"1","ddc":["570"],"day":"05","title":"Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids"},{"department":[{"_id":"TiVo"}],"has_accepted_license":"1","isi":1,"ddc":["570"],"day":"02","title":"Depolarization of echo chambers by random dynamical nudge","abstract":[{"text":"In social networks, users often engage with like-minded peers. This selective exposure to opinions might result in echo chambers, i.e., political fragmentation and social polarization of user interactions. When echo chambers form, opinions have a bimodal distribution with two peaks on opposite sides. In certain issues, where either extreme positions contain a degree of misinformation, neutral consensus is preferable for promoting discourse. In this paper, we use an opinion dynamics model that naturally forms echo chambers in order to find a feedback mechanism that bridges these communities and leads to a neutral consensus. We introduce the <jats:italic>random dynamical nudge</jats:italic> (RDN), which presents each agent with input from a random selection of other agents’ opinions and does not require surveillance of every person’s opinions. Our computational results in two different models suggest that the RDN leads to a unimodal distribution of opinions centered around the neutral consensus. Furthermore, the RDN is effective both for preventing the formation of echo chambers and also for depolarizing existing echo chambers. Due to the simple and robust nature of the RDN, social media networks might be able to implement a version of this self-feedback mechanism, when appropriate, to prevent the segregation of online communities on complex social issues.","lang":"eng"}],"article_number":"9234","oa_version":"Published Version","date_updated":"2023-08-04T09:26:30Z","intvolume":"        12","author":[{"last_name":"Currin","full_name":"Currin, Christopher","id":"e8321fc5-3091-11eb-8a53-83f309a11ac9","first_name":"Christopher","orcid":"0000-0002-4809-5059"},{"full_name":"Vera, Sebastián Vallejo","last_name":"Vera","first_name":"Sebastián Vallejo"},{"full_name":"Khaledi-Nasab, Ali","last_name":"Khaledi-Nasab","first_name":"Ali"}],"article_processing_charge":"No","acknowledgement":"CBC and AKN would like to thank Neuromatch Academy https://www.neuromatchacademy.org for introducing the authors to each other. We thank Dr. Krešimir Josic (University of Houston) , Fabian Baumann (Humboldt University) and Dr. Igor M. Sokolov (Humboldt University) for carefully reading the early versions of the manuscript and providing constructive feedback. CBC is supported by the German Deutscher Akademischer Austauschdienst (DAAD, https://daad.de), the South African National Research Foundation (NRF, https://nrf.ac.za), the University of Cape Town (UCT, https://uct.ac.za), and the NOMIS Foundation through the NOMIS Fellowships at IST Austria program (https://nomisfoundation.ch). SVV appreciate the generosity of Tecnológico de Monterrey for covering the publication fee.","date_created":"2023-01-16T09:48:30Z","file_date_updated":"2023-01-27T08:56:18Z","status":"public","publication":"Scientific Reports","publication_identifier":{"issn":["2045-2322"]},"_id":"12225","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"pmid":1,"scopus_import":"1","month":"06","type":"journal_article","volume":12,"publication_status":"published","citation":{"short":"C. Currin, S.V. Vera, A. Khaledi-Nasab, Scientific Reports 12 (2022).","ista":"Currin C, Vera SV, Khaledi-Nasab A. 2022. Depolarization of echo chambers by random dynamical nudge. Scientific Reports. 12, 9234.","chicago":"Currin, Christopher, Sebastián Vallejo Vera, and Ali Khaledi-Nasab. “Depolarization of Echo Chambers by Random Dynamical Nudge.” <i>Scientific Reports</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41598-022-12494-w\">https://doi.org/10.1038/s41598-022-12494-w</a>.","mla":"Currin, Christopher, et al. “Depolarization of Echo Chambers by Random Dynamical Nudge.” <i>Scientific Reports</i>, vol. 12, 9234, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41598-022-12494-w\">10.1038/s41598-022-12494-w</a>.","ama":"Currin C, Vera SV, Khaledi-Nasab A. Depolarization of echo chambers by random dynamical nudge. <i>Scientific Reports</i>. 2022;12. doi:<a href=\"https://doi.org/10.1038/s41598-022-12494-w\">10.1038/s41598-022-12494-w</a>","apa":"Currin, C., Vera, S. V., &#38; Khaledi-Nasab, A. (2022). Depolarization of echo chambers by random dynamical nudge. <i>Scientific Reports</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41598-022-12494-w\">https://doi.org/10.1038/s41598-022-12494-w</a>","ieee":"C. Currin, S. V. Vera, and A. Khaledi-Nasab, “Depolarization of echo chambers by random dynamical nudge,” <i>Scientific Reports</i>, vol. 12. Springer Nature, 2022."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","keyword":["Multidisciplinary"],"article_type":"original","date_published":"2022-06-02T00:00:00Z","doi":"10.1038/s41598-022-12494-w","language":[{"iso":"eng"}],"publisher":"Springer Nature","file":[{"date_created":"2023-01-27T08:56:18Z","success":1,"creator":"dernst","relation":"main_file","file_name":"2022_ScientificReports_Currin.pdf","access_level":"open_access","checksum":"e024a75f14ce5667795a31e44a259c52","file_id":"12418","file_size":3625627,"content_type":"application/pdf","date_updated":"2023-01-27T08:56:18Z"}],"oa":1,"quality_controlled":"1","year":"2022","external_id":{"isi":["000805561200024"],"pmid":["35654942"]}},{"external_id":{"isi":["000781953800001"],"pmid":["35414014"]},"year":"2022","quality_controlled":"1","publisher":"Springer Nature","date_published":"2022-04-12T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1186/s13059-022-02665-3","oa":1,"file":[{"success":1,"relation":"main_file","creator":"dernst","date_created":"2023-01-27T09:01:40Z","file_size":4939342,"date_updated":"2023-01-27T09:01:40Z","content_type":"application/pdf","checksum":"17bb091fec04d82ba20a3458c4cfd2bd","access_level":"open_access","file_name":"2022_GenomeBiology_Pokusaeva.pdf","file_id":"12419"}],"article_type":"original","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","type":"journal_article","volume":23,"citation":{"ieee":"V. Pokusaeva, A. R. Diez, L. Espinar, A. T. Pérez, and G. J. Filion, “Strand asymmetry influences mismatch resolution during single-strand annealing,” <i>Genome Biology</i>, vol. 23. Springer Nature, 2022.","apa":"Pokusaeva, V., Diez, A. R., Espinar, L., Pérez, A. T., &#38; Filion, G. J. (2022). Strand asymmetry influences mismatch resolution during single-strand annealing. <i>Genome Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s13059-022-02665-3\">https://doi.org/10.1186/s13059-022-02665-3</a>","ama":"Pokusaeva V, Diez AR, Espinar L, Pérez AT, Filion GJ. Strand asymmetry influences mismatch resolution during single-strand annealing. <i>Genome Biology</i>. 2022;23. doi:<a href=\"https://doi.org/10.1186/s13059-022-02665-3\">10.1186/s13059-022-02665-3</a>","short":"V. Pokusaeva, A.R. Diez, L. Espinar, A.T. Pérez, G.J. Filion, Genome Biology 23 (2022).","mla":"Pokusaeva, Victoria, et al. “Strand Asymmetry Influences Mismatch Resolution during Single-Strand Annealing.” <i>Genome Biology</i>, vol. 23, 93, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1186/s13059-022-02665-3\">10.1186/s13059-022-02665-3</a>.","chicago":"Pokusaeva, Victoria, Aránzazu Rosado Diez, Lorena Espinar, Albert Torelló Pérez, and Guillaume J. Filion. “Strand Asymmetry Influences Mismatch Resolution during Single-Strand Annealing.” <i>Genome Biology</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1186/s13059-022-02665-3\">https://doi.org/10.1186/s13059-022-02665-3</a>.","ista":"Pokusaeva V, Diez AR, Espinar L, Pérez AT, Filion GJ. 2022. Strand asymmetry influences mismatch resolution during single-strand annealing. Genome Biology. 23, 93."},"publication_status":"published","scopus_import":"1","month":"04","pmid":1,"_id":"12226","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"publication_identifier":{"issn":["1474-760X"]},"ec_funded":1,"related_material":{"link":[{"relation":"software","url":"https://github.com/cellcomplexitylab/strand_asymmetry "},{"url":"https://hub.docker.com/r/gui11aume/strand_asymmetry","relation":"software"}]},"publication":"Genome Biology","acknowledgement":"We acknowledge the financial support of the Natural Sciences and Engineering Research Council of Canada (NSERC RGPIN-2020-06377), the Spanish Ministry of Economy, Industry and Competitiveness (“Centro de Excelencia Severo Ochoa 2013-2017”, Plan Estatal PGC2018-099807-B-I00), of the CERCA Programme/Generalitat de Catalunya, and of the European Research Council (Synergy Grant 609989). VOP was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie programme (665385). We also acknowledge the support of the Spanish Ministry of Economy and Competitiveness (MEIC) to the EMBL partnership.","status":"public","file_date_updated":"2023-01-27T09:01:40Z","date_created":"2023-01-16T09:48:44Z","article_processing_charge":"No","author":[{"last_name":"Pokusaeva","full_name":"Pokusaeva, Victoria","first_name":"Victoria","id":"3184041C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7660-444X"},{"last_name":"Diez","full_name":"Diez, Aránzazu Rosado","first_name":"Aránzazu Rosado"},{"first_name":"Lorena","full_name":"Espinar, Lorena","last_name":"Espinar"},{"full_name":"Pérez, Albert Torelló","last_name":"Pérez","first_name":"Albert Torelló"},{"full_name":"Filion, Guillaume J.","last_name":"Filion","first_name":"Guillaume J."}],"abstract":[{"text":"Background: Biases of DNA repair can shape the nucleotide landscape of genomes at evolutionary timescales. The molecular mechanisms of those biases are still poorly understood because it is difficult to isolate the contributions of DNA repair from those of DNA damage.\r\n\r\nResults: Here, we develop a genome-wide assay whereby the same DNA lesion is repaired in different genomic contexts. We insert thousands of barcoded transposons carrying a reporter of DNA mismatch repair in the genome of mouse embryonic stem cells. Upon inducing a double-strand break between tandem repeats, a mismatch is generated if the break is repaired through single-strand annealing. The resolution of the mismatch showed a 60–80% bias in favor of the strand with the longest 3′ flap. The location of the lesion in the genome and the type of mismatch had little influence on the bias. Instead, we observe a complete reversal of the bias when the longest 3′ flap is moved to the opposite strand by changing the position of the double-strand break in the reporter.\r\n\r\nConclusions: These results suggest that the processing of the double-strand break has a major influence on the repair of mismatches during single-strand annealing.","lang":"eng"}],"intvolume":"        23","date_updated":"2025-03-31T16:01:11Z","article_number":"93","oa_version":"Published Version","day":"12","ddc":["570"],"title":"Strand asymmetry influences mismatch resolution during single-strand annealing","project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","call_identifier":"H2020"}],"department":[{"_id":"MaJö"}],"isi":1,"has_accepted_license":"1"},{"month":"10","scopus_import":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"12227","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","corr_author":"1","type":"journal_article","volume":5,"publication_status":"published","citation":{"ista":"Kovačič S, Schafzahl B, Matsko NB, Gruber K, Schmuck M, Koller S, Freunberger SA, Slugovc C. 2022. Carbon foams via ring-opening metathesis polymerization of emulsion templates: A facile method to make carbon current collectors for battery applications. ACS Applied Energy Materials. 5(11), 14381–14390.","mla":"Kovačič, Sebastijan, et al. “Carbon Foams via Ring-Opening Metathesis Polymerization of Emulsion Templates: A Facile Method to Make Carbon Current Collectors for Battery Applications.” <i>ACS Applied Energy Materials</i>, vol. 5, no. 11, American Chemical Society, 2022, pp. 14381–90, doi:<a href=\"https://doi.org/10.1021/acsaem.2c02787\">10.1021/acsaem.2c02787</a>.","chicago":"Kovačič, Sebastijan, Bettina Schafzahl, Nadejda B. Matsko, Katharina Gruber, Martin Schmuck, Stefan Koller, Stefan Alexander Freunberger, and Christian Slugovc. “Carbon Foams via Ring-Opening Metathesis Polymerization of Emulsion Templates: A Facile Method to Make Carbon Current Collectors for Battery Applications.” <i>ACS Applied Energy Materials</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acsaem.2c02787\">https://doi.org/10.1021/acsaem.2c02787</a>.","short":"S. Kovačič, B. Schafzahl, N.B. Matsko, K. Gruber, M. Schmuck, S. Koller, S.A. Freunberger, C. Slugovc, ACS Applied Energy Materials 5 (2022) 14381–14390.","ieee":"S. Kovačič <i>et al.</i>, “Carbon foams via ring-opening metathesis polymerization of emulsion templates: A facile method to make carbon current collectors for battery applications,” <i>ACS Applied Energy Materials</i>, vol. 5, no. 11. American Chemical Society, pp. 14381–14390, 2022.","apa":"Kovačič, S., Schafzahl, B., Matsko, N. B., Gruber, K., Schmuck, M., Koller, S., … Slugovc, C. (2022). Carbon foams via ring-opening metathesis polymerization of emulsion templates: A facile method to make carbon current collectors for battery applications. <i>ACS Applied Energy Materials</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsaem.2c02787\">https://doi.org/10.1021/acsaem.2c02787</a>","ama":"Kovačič S, Schafzahl B, Matsko NB, et al. Carbon foams via ring-opening metathesis polymerization of emulsion templates: A facile method to make carbon current collectors for battery applications. <i>ACS Applied Energy Materials</i>. 2022;5(11):14381-14390. doi:<a href=\"https://doi.org/10.1021/acsaem.2c02787\">10.1021/acsaem.2c02787</a>"},"language":[{"iso":"eng"}],"date_published":"2022-10-16T00:00:00Z","publisher":"American Chemical Society","doi":"10.1021/acsaem.2c02787","issue":"11","file":[{"creator":"dernst","relation":"main_file","success":1,"date_created":"2023-01-27T09:09:15Z","content_type":"application/pdf","date_updated":"2023-01-27T09:09:15Z","file_size":13105589,"file_id":"12420","file_name":"2022_AppliedEnergyMaterials_Kovacic.pdf","checksum":"572d15c250ab83d44f4e2c3aeb5f7388","access_level":"open_access"}],"oa":1,"keyword":["Electrical and Electronic Engineering","Materials Chemistry","Electrochemistry","Energy Engineering and Power Technology","Chemical Engineering (miscellaneous)"],"article_type":"original","page":"14381-14390","external_id":{"isi":["000875635900001"]},"quality_controlled":"1","year":"2022","ddc":["540"],"day":"16","title":"Carbon foams via ring-opening metathesis polymerization of emulsion templates: A facile method to make carbon current collectors for battery applications","department":[{"_id":"StFr"}],"isi":1,"has_accepted_license":"1","author":[{"first_name":"Sebastijan","full_name":"Kovačič, Sebastijan","last_name":"Kovačič"},{"first_name":"Bettina","full_name":"Schafzahl, Bettina","last_name":"Schafzahl"},{"last_name":"Matsko","full_name":"Matsko, Nadejda B.","first_name":"Nadejda B."},{"first_name":"Katharina","full_name":"Gruber, Katharina","last_name":"Gruber"},{"first_name":"Martin","last_name":"Schmuck","full_name":"Schmuck, Martin"},{"first_name":"Stefan","last_name":"Koller","full_name":"Koller, Stefan"},{"full_name":"Freunberger, Stefan Alexander","last_name":"Freunberger","orcid":"0000-0003-2902-5319","first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425"},{"last_name":"Slugovc","full_name":"Slugovc, Christian","first_name":"Christian"}],"abstract":[{"lang":"eng","text":"Polydicyclopentadiene (pDCPD), a thermoset with excellent mechanical properties, has enormous potential as a lightweight, tough, and stable matrix material owing to its highly cross-linked macromolecular network. This work describes generating pDCPD-based foams and hierarchically porous carbons derived therefrom by combining ring-opening metathesis polymerization (ROMP) of DCPD, high internal phase emulsions (HIPEs) as structural templates, and subsequent carbonization. The structure and function of the carbon foams were characterized and discussed in detail using scanning electron, transmission electron, or atomic force microscopy (SEM, TEM, AFM), electron energy-loss spectroscopy (TEM-EELS), N2 sorption, and analyses of electrical conductivity as well as mechanical properties. The resulting materials exhibited uniform, shape-retaining shrinkage of only ∼1/3 after carbonization. No structural failure was observed even when the pDCPD precursor foams were heated to 1400 °C. Instead, the high porosity, void size, and 3D interconnectivity were fully preserved, and the void diameters could be adjusted between 87 and 2.5 μm. Moreover, foams have a carbon content >97%, an electronic conductivity of up to 2800 S·m–1, a Young’s modulus of up to 2.1 GPa, and a specific surface area of up to 1200 m2·g–1. Surprisingly, the pDCPD foams were carbonized into shapes other than monoliths, such as 10’s of micron thick membranes or foamy coatings adhered to a metal foil or grid substrate. The latter coatings even adhere upon bending. Finally, as a use case, carbonized foams were applied as porous cathodes for Li–O2 batteries where the foams show a favorable combination of porosity, active surface area, and pore size for outstanding capacity."}],"oa_version":"Published Version","intvolume":"         5","date_updated":"2024-10-09T21:03:48Z","acknowledgement":"S.K. acknowledges the financial support from the Slovenian Research Agency (grants P1-0021, P2-0150). Support by Graz University of Technology (LP-03 – Porous Materials@Work) and from VARTA Innovation GmbH is kindly acknowledged. We thank Umicore for providing the initiator and Matjaž Mazaj (National Institute of Chemistry, Ljubljana) and Karel Jerabek (Czech Academy of Sciences) for measurements and fruitful discussions. S.A.F. is indebted to the Austrian Federal Ministry of Science, Research and Economy; the Austrian Research Promotion Agency (Grant No. 845364); and ISTA for support.","date_created":"2023-01-16T09:48:53Z","status":"public","file_date_updated":"2023-01-27T09:09:15Z","article_processing_charge":"No","publication_identifier":{"issn":["2574-0962"]},"publication":"ACS Applied Energy Materials"},{"year":"2022","quality_controlled":"1","page":"2705–2718","external_id":{"arxiv":["2201.05677"]},"publisher":"Association for Computing Machinery","date_published":"2022-11-01T00:00:00Z","doi":"10.1145/3548606.3559361","language":[{"iso":"eng"}],"oa":1,"type":"conference","citation":{"ieee":"A. Spiegelman, N. Giridharan, A. Sonnino, and E. Kokoris Kogias, “Bullshark: DAG BFT protocols made practical,” in <i>Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security</i>, Los Angeles, CA, United States, 2022, pp. 2705–2718.","apa":"Spiegelman, A., Giridharan, N., Sonnino, A., &#38; Kokoris Kogias, E. (2022). Bullshark: DAG BFT protocols made practical. In <i>Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security</i> (pp. 2705–2718). Los Angeles, CA, United States: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3548606.3559361\">https://doi.org/10.1145/3548606.3559361</a>","ama":"Spiegelman A, Giridharan N, Sonnino A, Kokoris Kogias E. Bullshark: DAG BFT protocols made practical. In: <i>Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security</i>. Association for Computing Machinery; 2022:2705–2718. doi:<a href=\"https://doi.org/10.1145/3548606.3559361\">10.1145/3548606.3559361</a>","ista":"Spiegelman A, Giridharan N, Sonnino A, Kokoris Kogias E. 2022. Bullshark: DAG BFT protocols made practical. Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security. CCS: Conference on Computer and Communications Security, 2705–2718.","mla":"Spiegelman, Alexander, et al. “Bullshark: DAG BFT Protocols Made Practical.” <i>Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security</i>, Association for Computing Machinery, 2022, pp. 2705–2718, doi:<a href=\"https://doi.org/10.1145/3548606.3559361\">10.1145/3548606.3559361</a>.","chicago":"Spiegelman, Alexander, Neil Giridharan, Alberto Sonnino, and Eleftherios Kokoris Kogias. “Bullshark: DAG BFT Protocols Made Practical.” In <i>Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security</i>, 2705–2718. Association for Computing Machinery, 2022. <a href=\"https://doi.org/10.1145/3548606.3559361\">https://doi.org/10.1145/3548606.3559361</a>.","short":"A. Spiegelman, N. Giridharan, A. Sonnino, E. Kokoris Kogias, in:, Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security, Association for Computing Machinery, 2022, pp. 2705–2718."},"publication_status":"published","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12229","scopus_import":"1","month":"11","arxiv":1,"publication":"Proceedings of the 2022 ACM SIGSAC Conference on Computer and Communications Security","publication_identifier":{"isbn":["9781450394505"]},"conference":{"name":"CCS: Conference on Computer and Communications Security","end_date":"2022-11-11","start_date":"2022-11-07","location":"Los Angeles, CA, United States"},"article_processing_charge":"No","status":"public","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2201.05677"}],"date_created":"2023-01-16T09:49:48Z","abstract":[{"text":"We present Bullshark, the first directed acyclic graph (DAG) based asynchronous Byzantine Atomic Broadcast protocol that is optimized for the common synchronous case. Like previous DAG-based BFT protocols [19, 25], Bullshark requires no extra communication to achieve consensus on top of building the DAG. That is, parties can totally order the vertices of the DAG by interpreting their local view of the DAG edges. Unlike other asynchronous DAG-based protocols, Bullshark provides a practical low latency fast-path that exploits synchronous periods and deprecates the need for notoriously complex view-change and view-synchronization mechanisms. Bullshark achieves this while maintaining all the desired properties of its predecessor DAG-Rider [25]. Namely, it has optimal amortized communication complexity, it provides fairness and asynchronous liveness, and safety is guaranteed even under a quantum adversary.\r\n\r\nIn order to show the practicality and simplicity of our approach, we also introduce a standalone partially synchronous version of Bullshark, which we evaluate against the state of the art. The implemented protocol is embarrassingly simple (200 LOC on top of an existing DAG-based mempool implementation). It is highly efficient, achieving for example, 125,000 transactions per second with a 2 seconds latency for a deployment of 50 parties. In the same setting, the state of the art pays a steep 50% latency increase as it optimizes for asynchrony.","lang":"eng"}],"date_updated":"2025-07-10T11:50:26Z","oa_version":"Preprint","author":[{"first_name":"Alexander","last_name":"Spiegelman","full_name":"Spiegelman, Alexander"},{"first_name":"Neil","last_name":"Giridharan","full_name":"Giridharan, Neil"},{"full_name":"Sonnino, Alberto","last_name":"Sonnino","first_name":"Alberto"},{"full_name":"Kokoris Kogias, Eleftherios","last_name":"Kokoris Kogias","first_name":"Eleftherios","id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30"}],"department":[{"_id":"ElKo"}],"day":"01","title":"Bullshark: DAG BFT protocols made practical"},{"issue":"21","doi":"10.1242/dev.200215","language":[{"iso":"eng"}],"publisher":"The Company of Biologists","date_published":"2022-11-01T00:00:00Z","oa":1,"file":[{"date_created":"2023-01-27T10:36:50Z","success":1,"relation":"main_file","creator":"dernst","file_name":"2022_Development_Kogure.pdf","access_level":"open_access","checksum":"871b9c58eb79b9e60752de25a46938d6","file_id":"12423","file_size":9160451,"content_type":"application/pdf","date_updated":"2023-01-27T10:36:50Z"}],"keyword":["Developmental Biology","Molecular Biology"],"article_type":"original","external_id":{"pmid":["36227591"],"isi":["000903991700002"]},"year":"2022","quality_controlled":"1","month":"11","scopus_import":"1","pmid":1,"_id":"12231","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","corr_author":"1","type":"journal_article","volume":149,"citation":{"ieee":"Y. S. Kogure <i>et al.</i>, “Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona,” <i>Development</i>, vol. 149, no. 21. The Company of Biologists, 2022.","apa":"Kogure, Y. S., Muraoka, H., Koizumi, W. C., Gelin-alessi, R., Godard, B. G., Oka, K., … Hotta, K. (2022). Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona. <i>Development</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/dev.200215\">https://doi.org/10.1242/dev.200215</a>","ama":"Kogure YS, Muraoka H, Koizumi WC, et al. Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona. <i>Development</i>. 2022;149(21). doi:<a href=\"https://doi.org/10.1242/dev.200215\">10.1242/dev.200215</a>","mla":"Kogure, Yuki S., et al. “Admp Regulates Tail Bending by Controlling Ventral Epidermal Cell Polarity via Phosphorylated Myosin Localization in Ciona.” <i>Development</i>, vol. 149, no. 21, dev200215, The Company of Biologists, 2022, doi:<a href=\"https://doi.org/10.1242/dev.200215\">10.1242/dev.200215</a>.","chicago":"Kogure, Yuki S., Hiromochi Muraoka, Wataru C. Koizumi, Raphaël Gelin-alessi, Benoit G Godard, Kotaro Oka, Carl-Philipp J Heisenberg, and Kohji Hotta. “Admp Regulates Tail Bending by Controlling Ventral Epidermal Cell Polarity via Phosphorylated Myosin Localization in Ciona.” <i>Development</i>. The Company of Biologists, 2022. <a href=\"https://doi.org/10.1242/dev.200215\">https://doi.org/10.1242/dev.200215</a>.","ista":"Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard BG, Oka K, Heisenberg C-PJ, Hotta K. 2022. Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona. Development. 149(21), dev200215.","short":"Y.S. Kogure, H. Muraoka, W.C. Koizumi, R. Gelin-alessi, B.G. Godard, K. Oka, C.-P.J. Heisenberg, K. Hotta, Development 149 (2022)."},"publication_status":"published","acknowledgement":"iona intestinalis adults were provided by Dr Yutaka Satou (Kyoto University) and Dr Manabu Yoshida (the University of Tokyo) with support from the National Bio-Resource Project of AMED, Japan. We thank Dr Hidehiko Hashimoto and Dr Yuji Mizotani for technical information about 1P-myosin antibody staining. We thank Dr Kaoru Imai and Dr Yutaka Satou for valuable discussion about Admp and for the DNA construct of Bmp2/4 under the Dlx.b upstream sequence. We thank Ms Maki Kogure for constructing the FUSION360 of the intercalating epidermal cell.\r\nThis work was supported by funding from the Japan Society for the Promotion of Science (JP16H01451, JP21H00440). Open Access funding provided by Keio University: Keio Gijuku Daigaku.","status":"public","file_date_updated":"2023-01-27T10:36:50Z","date_created":"2023-01-16T09:50:12Z","article_processing_charge":"No","publication_identifier":{"eissn":["1477-9129"],"issn":["0950-1991"]},"publication":"Development","day":"01","ddc":["570"],"title":"Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona","department":[{"_id":"CaHe"}],"has_accepted_license":"1","isi":1,"author":[{"first_name":"Yuki S.","full_name":"Kogure, Yuki S.","last_name":"Kogure"},{"full_name":"Muraoka, Hiromochi","last_name":"Muraoka","first_name":"Hiromochi"},{"first_name":"Wataru C.","last_name":"Koizumi","full_name":"Koizumi, Wataru C."},{"full_name":"Gelin-alessi, Raphaël","last_name":"Gelin-alessi","first_name":"Raphaël"},{"last_name":"Godard","full_name":"Godard, Benoit G","id":"33280250-F248-11E8-B48F-1D18A9856A87","first_name":"Benoit G"},{"first_name":"Kotaro","full_name":"Oka, Kotaro","last_name":"Oka"},{"last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566"},{"full_name":"Hotta, Kohji","last_name":"Hotta","first_name":"Kohji"}],"abstract":[{"lang":"eng","text":"Ventral tail bending, which is transient but pronounced, is found in many chordate embryos and constitutes an interesting model of how tissue interactions control embryo shape. Here, we identify one key upstream regulator of ventral tail bending in embryos of the ascidian Ciona. We show that during the early tailbud stages, ventral epidermal cells exhibit a boat-shaped morphology (boat cell) with a narrow apical surface where phosphorylated myosin light chain (pMLC) accumulates. We further show that interfering with the function of the BMP ligand Admp led to pMLC localizing to the basal instead of the apical side of ventral epidermal cells and a reduced number of boat cells. Finally, we show that cutting ventral epidermal midline cells at their apex using an ultraviolet laser relaxed ventral tail bending. Based on these results, we propose a previously unreported function for Admp in localizing pMLC to the apical side of ventral epidermal cells, which causes the tail to bend ventrally by resisting antero-posterior notochord extension at the ventral side of the tail."}],"date_updated":"2024-10-09T21:03:48Z","intvolume":"       149","article_number":"dev200215","oa_version":"Published Version"},{"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","citation":{"ieee":"G. Cipolloni, L. Erdös, and D. J. Schröder, “Density of small singular values of the shifted real Ginibre ensemble,” <i>Annales Henri Poincaré</i>, vol. 23, no. 11. Springer Nature, pp. 3981–4002, 2022.","ama":"Cipolloni G, Erdös L, Schröder DJ. Density of small singular values of the shifted real Ginibre ensemble. <i>Annales Henri Poincaré</i>. 2022;23(11):3981-4002. doi:<a href=\"https://doi.org/10.1007/s00023-022-01188-8\">10.1007/s00023-022-01188-8</a>","apa":"Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2022). Density of small singular values of the shifted real Ginibre ensemble. <i>Annales Henri Poincaré</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00023-022-01188-8\">https://doi.org/10.1007/s00023-022-01188-8</a>","mla":"Cipolloni, Giorgio, et al. “Density of Small Singular Values of the Shifted Real Ginibre Ensemble.” <i>Annales Henri Poincaré</i>, vol. 23, no. 11, Springer Nature, 2022, pp. 3981–4002, doi:<a href=\"https://doi.org/10.1007/s00023-022-01188-8\">10.1007/s00023-022-01188-8</a>.","ista":"Cipolloni G, Erdös L, Schröder DJ. 2022. Density of small singular values of the shifted real Ginibre ensemble. Annales Henri Poincaré. 23(11), 3981–4002.","chicago":"Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Density of Small Singular Values of the Shifted Real Ginibre Ensemble.” <i>Annales Henri Poincaré</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s00023-022-01188-8\">https://doi.org/10.1007/s00023-022-01188-8</a>.","short":"G. Cipolloni, L. Erdös, D.J. Schröder, Annales Henri Poincaré 23 (2022) 3981–4002."},"publication_status":"published","type":"journal_article","volume":23,"scopus_import":"1","month":"11","_id":"12232","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"external_id":{"isi":["000796323500001"]},"page":"3981-4002","year":"2022","quality_controlled":"1","oa":1,"file":[{"file_size":1333638,"content_type":"application/pdf","date_updated":"2023-01-27T11:06:47Z","file_name":"2022_AnnalesHenriP_Cipolloni.pdf","checksum":"5582f059feeb2f63e2eb68197a34d7dc","access_level":"open_access","file_id":"12424","success":1,"creator":"dernst","relation":"main_file","date_created":"2023-01-27T11:06:47Z"}],"issue":"11","publisher":"Springer Nature","doi":"10.1007/s00023-022-01188-8","date_published":"2022-11-01T00:00:00Z","language":[{"iso":"eng"}],"article_type":"original","keyword":["Mathematical Physics","Nuclear and High Energy Physics","Statistical and Nonlinear Physics"],"author":[{"first_name":"Giorgio","id":"42198EFA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4901-7992","last_name":"Cipolloni","full_name":"Cipolloni, Giorgio"},{"last_name":"Erdös","full_name":"Erdös, László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","first_name":"László","orcid":"0000-0001-5366-9603"},{"orcid":"0000-0002-2904-1856","id":"408ED176-F248-11E8-B48F-1D18A9856A87","first_name":"Dominik J","full_name":"Schröder, Dominik J","last_name":"Schröder"}],"date_updated":"2023-08-04T09:33:52Z","intvolume":"        23","oa_version":"Published Version","abstract":[{"lang":"eng","text":"We derive a precise asymptotic formula for the density of the small singular values of the real Ginibre matrix ensemble shifted by a complex parameter z as the dimension tends to infinity. For z away from the real axis the formula coincides with that for the complex Ginibre ensemble we derived earlier in Cipolloni et al. (Prob Math Phys 1:101–146, 2020). On the level of the one-point function of the low lying singular values we thus confirm the transition from real to complex Ginibre ensembles as the shift parameter z becomes genuinely complex; the analogous phenomenon has been well known for eigenvalues. We use the superbosonization formula (Littelmann et al. in Comm Math Phys 283:343–395, 2008) in a regime where the main contribution comes from a three dimensional saddle manifold."}],"title":"Density of small singular values of the shifted real Ginibre ensemble","day":"01","ddc":["510"],"has_accepted_license":"1","isi":1,"department":[{"_id":"LaEr"}],"publication_identifier":{"issn":["1424-0637"],"eissn":["1424-0661"]},"publication":"Annales Henri Poincaré","file_date_updated":"2023-01-27T11:06:47Z","status":"public","date_created":"2023-01-16T09:50:26Z","acknowledgement":"Open access funding provided by Swiss Federal Institute of Technology Zurich. Supported by Dr. Max Rössler, the Walter Haefner Foundation and the ETH Zürich Foundation.","article_processing_charge":"No"},{"article_type":"original","publisher":"Institute of Electrical and Electronics Engineers","date_published":"2022-11-01T00:00:00Z","doi":"10.1109/tcomm.2022.3211101","language":[{"iso":"eng"}],"issue":"11","oa":1,"quality_controlled":"1","year":"2022","page":"7134-7145","external_id":{"isi":["000937284600006"],"arxiv":["2109.02122"]},"_id":"12233","month":"11","scopus_import":"1","arxiv":1,"volume":70,"type":"journal_article","publication_status":"published","citation":{"ieee":"N. Doan, S. A. Hashemi, M. Mondelli, and W. J. Gross, “Decoding Reed-Muller codes with successive codeword permutations,” <i>IEEE Transactions on Communications</i>, vol. 70, no. 11. Institute of Electrical and Electronics Engineers, pp. 7134–7145, 2022.","ama":"Doan N, Hashemi SA, Mondelli M, Gross WJ. Decoding Reed-Muller codes with successive codeword permutations. <i>IEEE Transactions on Communications</i>. 2022;70(11):7134-7145. doi:<a href=\"https://doi.org/10.1109/tcomm.2022.3211101\">10.1109/tcomm.2022.3211101</a>","apa":"Doan, N., Hashemi, S. A., Mondelli, M., &#38; Gross, W. J. (2022). Decoding Reed-Muller codes with successive codeword permutations. <i>IEEE Transactions on Communications</i>. Institute of Electrical and Electronics Engineers. <a href=\"https://doi.org/10.1109/tcomm.2022.3211101\">https://doi.org/10.1109/tcomm.2022.3211101</a>","short":"N. Doan, S.A. Hashemi, M. Mondelli, W.J. Gross, IEEE Transactions on Communications 70 (2022) 7134–7145.","mla":"Doan, Nghia, et al. “Decoding Reed-Muller Codes with Successive Codeword Permutations.” <i>IEEE Transactions on Communications</i>, vol. 70, no. 11, Institute of Electrical and Electronics Engineers, 2022, pp. 7134–45, doi:<a href=\"https://doi.org/10.1109/tcomm.2022.3211101\">10.1109/tcomm.2022.3211101</a>.","chicago":"Doan, Nghia, Seyyed Ali Hashemi, Marco Mondelli, and Warren J. Gross. “Decoding Reed-Muller Codes with Successive Codeword Permutations.” <i>IEEE Transactions on Communications</i>. Institute of Electrical and Electronics Engineers, 2022. <a href=\"https://doi.org/10.1109/tcomm.2022.3211101\">https://doi.org/10.1109/tcomm.2022.3211101</a>.","ista":"Doan N, Hashemi SA, Mondelli M, Gross WJ. 2022. Decoding Reed-Muller codes with successive codeword permutations. IEEE Transactions on Communications. 70(11), 7134–7145."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"No","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2109.02122","open_access":"1"}],"date_created":"2023-01-16T09:50:38Z","status":"public","publication":"IEEE Transactions on Communications","publication_identifier":{"issn":["0090-6778"],"eissn":["1558-0857"]},"department":[{"_id":"MaMo"}],"isi":1,"day":"01","title":"Decoding Reed-Muller codes with successive codeword permutations","abstract":[{"lang":"eng","text":"A novel recursive list decoding (RLD) algorithm for Reed-Muller (RM) codes based on successive permutations (SP) of the codeword is presented. A low-complexity SP scheme applied to a subset of the symmetry group of RM codes is first proposed to carefully select a good codeword permutation on the fly. Then, the proposed SP technique is integrated into an improved RLD algorithm that initializes different decoding paths with random codeword permutations, which are sampled from the full symmetry group of RM codes. Finally, efficient latency and complexity reduction schemes are introduced that virtually preserve the error-correction performance of the proposed decoder. Simulation results demonstrate that at the target frame error rate of 10−3 for the RM code of length 256 with 163 information bits, the proposed decoder reduces 6% of the computational complexity and 22% of the decoding latency of the state-of-the-art semi-parallel simplified successive-cancellation decoder with fast Hadamard transform (SSC-FHT) that uses 96 permutations from the full symmetry group of RM codes, while relatively maintaining the error-correction performance and memory consumption of the semi-parallel permuted SSC-FHT decoder."}],"oa_version":"Preprint","date_updated":"2023-08-04T09:34:43Z","intvolume":"        70","author":[{"first_name":"Nghia","last_name":"Doan","full_name":"Doan, Nghia"},{"first_name":"Seyyed Ali","last_name":"Hashemi","full_name":"Hashemi, Seyyed Ali"},{"orcid":"0000-0002-3242-7020","first_name":"Marco","id":"27EB676C-8706-11E9-9510-7717E6697425","full_name":"Mondelli, Marco","last_name":"Mondelli"},{"first_name":"Warren J.","full_name":"Gross, Warren J.","last_name":"Gross"}]},{"title":"Digest: On the origin of a possible hybrid species","ddc":["570"],"day":"01","isi":1,"has_accepted_license":"1","department":[{"_id":"NiBa"}],"author":[{"first_name":"Sean","id":"43161670-5719-11EA-8025-FABC3DDC885E","full_name":"Stankowski, Sean","last_name":"Stankowski"}],"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","oa_version":"Published Version","intvolume":"        76","date_updated":"2025-06-11T13:40:40Z","abstract":[{"text":"Hybrid speciation—the origin of new species resulting from the hybridization of genetically divergent lineages—was once considered rare, but genomic data suggest that it may occur more often than once thought. In this study, Noguerales and Ortego found genomic evidence supporting the hybrid origin of a grasshopper that is able to exploit a broader range of host plants than either of its putative parents.","lang":"eng"}],"date_created":"2023-01-16T09:50:48Z","file_date_updated":"2023-01-27T11:28:38Z","status":"public","article_processing_charge":"Yes (via OA deal)","publication_identifier":{"eissn":["1558-5646"],"issn":["0014-3820"]},"publication":"Evolution","pmid":1,"month":"11","scopus_import":"1","tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"_id":"12234","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_status":"published","citation":{"ama":"Stankowski S. Digest: On the origin of a possible hybrid species. <i>Evolution</i>. 2022;76(11):2784-2785. doi:<a href=\"https://doi.org/10.1111/evo.14632\">10.1111/evo.14632</a>","apa":"Stankowski, S. (2022). Digest: On the origin of a possible hybrid species. <i>Evolution</i>. Wiley. <a href=\"https://doi.org/10.1111/evo.14632\">https://doi.org/10.1111/evo.14632</a>","ieee":"S. Stankowski, “Digest: On the origin of a possible hybrid species,” <i>Evolution</i>, vol. 76, no. 11. Wiley, pp. 2784–2785, 2022.","short":"S. Stankowski, Evolution 76 (2022) 2784–2785.","mla":"Stankowski, Sean. “Digest: On the Origin of a Possible Hybrid Species.” <i>Evolution</i>, vol. 76, no. 11, Wiley, 2022, pp. 2784–85, doi:<a href=\"https://doi.org/10.1111/evo.14632\">10.1111/evo.14632</a>.","ista":"Stankowski S. 2022. Digest: On the origin of a possible hybrid species. Evolution. 76(11), 2784–2785.","chicago":"Stankowski, Sean. “Digest: On the Origin of a Possible Hybrid Species.” <i>Evolution</i>. Wiley, 2022. <a href=\"https://doi.org/10.1111/evo.14632\">https://doi.org/10.1111/evo.14632</a>."},"corr_author":"1","type":"journal_article","volume":76,"file":[{"content_type":"application/pdf","date_updated":"2023-01-27T11:28:38Z","file_size":287282,"file_id":"12425","file_name":"2022_Evolution_Stankowski.pdf","checksum":"4c0f05083b414ac0323a1b9ee1abc275","access_level":"open_access","creator":"dernst","relation":"main_file","success":1,"date_created":"2023-01-27T11:28:38Z"}],"oa":1,"date_published":"2022-11-01T00:00:00Z","publisher":"Wiley","language":[{"iso":"eng"}],"doi":"10.1111/evo.14632","issue":"11","article_type":"original","keyword":["General Agricultural and Biological Sciences","Genetics","Ecology","Evolution","Behavior and Systematics"],"external_id":{"isi":["000855751600001"],"pmid":["36112597"]},"page":"2784-2785","quality_controlled":"1","year":"2022"},{"tmp":{"short":"CC BY-NC-ND (4.0)","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"_id":"12235","pmid":1,"month":"11","scopus_import":"1","volume":109,"corr_author":"1","type":"journal_article","publication_status":"published","citation":{"ieee":"M. Patxot <i>et al.</i>, “Haematological changes from conception to childbirth: An indicator of major pregnancy complications,” <i>European Journal of Haematology</i>, vol. 109, no. 5. Wiley, pp. 566–575, 2022.","apa":"Patxot, M., Stojanov, M., Ojavee, S. E., Gobert, R. P., Kutalik, Z., Gavillet, M., … Robinson, M. R. (2022). Haematological changes from conception to childbirth: An indicator of major pregnancy complications. <i>European Journal of Haematology</i>. Wiley. <a href=\"https://doi.org/10.1111/ejh.13844\">https://doi.org/10.1111/ejh.13844</a>","ama":"Patxot M, Stojanov M, Ojavee SE, et al. Haematological changes from conception to childbirth: An indicator of major pregnancy complications. <i>European Journal of Haematology</i>. 2022;109(5):566-575. doi:<a href=\"https://doi.org/10.1111/ejh.13844\">10.1111/ejh.13844</a>","ista":"Patxot M, Stojanov M, Ojavee SE, Gobert RP, Kutalik Z, Gavillet M, Baud D, Robinson MR. 2022. Haematological changes from conception to childbirth: An indicator of major pregnancy complications. European Journal of Haematology. 109(5), 566–575.","mla":"Patxot, Marion, et al. “Haematological Changes from Conception to Childbirth: An Indicator of Major Pregnancy Complications.” <i>European Journal of Haematology</i>, vol. 109, no. 5, Wiley, 2022, pp. 566–75, doi:<a href=\"https://doi.org/10.1111/ejh.13844\">10.1111/ejh.13844</a>.","chicago":"Patxot, Marion, Miloš Stojanov, Sven Erik Ojavee, Rosanna Pescini Gobert, Zoltán Kutalik, Mathilde Gavillet, David Baud, and Matthew Richard Robinson. “Haematological Changes from Conception to Childbirth: An Indicator of Major Pregnancy Complications.” <i>European Journal of Haematology</i>. Wiley, 2022. <a href=\"https://doi.org/10.1111/ejh.13844\">https://doi.org/10.1111/ejh.13844</a>.","short":"M. Patxot, M. Stojanov, S.E. Ojavee, R.P. Gobert, Z. Kutalik, M. Gavillet, D. Baud, M.R. Robinson, European Journal of Haematology 109 (2022) 566–575."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","keyword":["Hematology","General Medicine"],"article_type":"original","publisher":"Wiley","date_published":"2022-11-01T00:00:00Z","language":[{"iso":"eng"}],"doi":"10.1111/ejh.13844","issue":"5","file":[{"content_type":"application/pdf","date_updated":"2023-01-27T11:42:43Z","file_size":1225073,"file_id":"12426","file_name":"2022_EuropJourHaematology_Patxot.pdf","access_level":"open_access","checksum":"a676d732f67c2990197e34f96b219370","creator":"dernst","relation":"main_file","success":1,"date_created":"2023-01-27T11:42:43Z"}],"oa":1,"quality_controlled":"1","year":"2022","page":"566-575","external_id":{"pmid":["36059200"],"isi":["000849690500001"]},"department":[{"_id":"MaRo"}],"isi":1,"has_accepted_license":"1","ddc":["570","610"],"day":"01","title":"Haematological changes from conception to childbirth: An indicator of major pregnancy complications","abstract":[{"lang":"eng","text":"Background: About 800 women die every day worldwide from pregnancy-related complications, including excessive blood loss, infections and high-blood pressure (World Health Organization, 2019). To improve screening for high-risk pregnancies, we set out to identify patterns of maternal hematological changes associated with future pregnancy complications.\r\n\r\nMethods: Using mixed effects models, we established changes in 14 complete blood count (CBC) parameters for 1710 healthy pregnancies and compared them to measurements from 98 pregnancy-induced hypertension, 106 gestational diabetes and 339 postpartum hemorrhage cases.\r\n\r\nResults: Results show interindividual variations, but good individual repeatability in CBC values during physiological pregnancies, allowing the identification of specific alterations in women with obstetric complications. For example, in women with uncomplicated pregnancies, haemoglobin count decreases of 0.12 g/L (95% CI −0.16, −0.09) significantly per gestation week (p value <.001). Interestingly, this decrease is three times more pronounced in women who will develop pregnancy-induced hypertension, with an additional decrease of 0.39 g/L (95% CI −0.51, −0.26). We also confirm that obstetric complications and white CBC predict the likelihood of giving birth earlier during pregnancy.\r\n\r\nConclusion: We provide a comprehensive description of the associations between haematological changes through pregnancy and three major obstetric complications to support strategies for prevention, early-diagnosis and maternal care."}],"oa_version":"Published Version","intvolume":"       109","date_updated":"2024-10-09T21:03:49Z","author":[{"first_name":"Marion","last_name":"Patxot","full_name":"Patxot, Marion"},{"last_name":"Stojanov","full_name":"Stojanov, Miloš","first_name":"Miloš"},{"full_name":"Ojavee, Sven Erik","last_name":"Ojavee","first_name":"Sven Erik"},{"full_name":"Gobert, Rosanna Pescini","last_name":"Gobert","first_name":"Rosanna Pescini"},{"last_name":"Kutalik","full_name":"Kutalik, Zoltán","first_name":"Zoltán"},{"first_name":"Mathilde","last_name":"Gavillet","full_name":"Gavillet, Mathilde"},{"last_name":"Baud","full_name":"Baud, David","first_name":"David"},{"full_name":"Robinson, Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"}],"article_processing_charge":"No","acknowledgement":"This project was funded by an SNSF Eccellenza Grant to MRR (PCEGP3-181181), and by core funding from the Institute of Science and Technology Austria. We would like to thank the participants of the study and all the midwives and doctors involved for the computerized obstetrical data from the CHUV Maternity Hospital. Open access funding provided by Universite de Lausanne.","date_created":"2023-01-16T09:50:58Z","file_date_updated":"2023-01-27T11:42:43Z","status":"public","publication":"European Journal of Haematology","publication_identifier":{"eissn":["1600-0609"],"issn":["0902-4441"]}},{"acknowledgement":"This work was supported by the Spanish MCIN project COMBENERGY (PID2019-105490RB-C32). X.W. and L.Y. thank the China Scholarship Council (CSC) for the scholarship support.","status":"public","date_created":"2023-01-16T09:51:10Z","article_processing_charge":"No","publication_identifier":{"eissn":["1944-8252"],"issn":["1944-8244"]},"publication":"ACS Applied Materials & Interfaces","day":"14","title":"CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction","department":[{"_id":"MaIb"}],"isi":1,"author":[{"full_name":"Wang, Xiang","last_name":"Wang","first_name":"Xiang"},{"first_name":"Yong","full_name":"Zuo, Yong","last_name":"Zuo"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona","full_name":"Horta, Sharona","last_name":"Horta"},{"full_name":"He, Ren","last_name":"He","first_name":"Ren"},{"last_name":"Yang","full_name":"Yang, Linlin","first_name":"Linlin"},{"first_name":"Ahmad","last_name":"Ostovari Moghaddam","full_name":"Ostovari Moghaddam, Ahmad"},{"full_name":"Ibáñez, Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria"},{"full_name":"Qi, Xueqiang","last_name":"Qi","first_name":"Xueqiang"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"abstract":[{"lang":"eng","text":"High-entropy materials offer numerous advantages as catalysts, including a flexible composition to tune the catalytic activity and selectivity and a large variety of adsorption/reaction sites for multistep or multiple reactions. Herein, we report on the synthesis, properties, and electrocatalytic performance of an amorphous high-entropy boride based on abundant transition metals, CoFeNiMnZnB. This metal boride provides excellent performance toward the oxygen evolution reaction (OER), including a low overpotential of 261 mV at 10 mA cm–2, a reduced Tafel slope of 56.8 mV dec–1, and very high stability. The outstanding OER performance of CoFeNiMnZnB is attributed to the synergistic interactions between the different metals, the leaching of Zn ions, the generation of oxygen vacancies, and the in situ formation of an amorphous oxyhydroxide at the CoFeNiMnZnB surface during the OER."}],"intvolume":"        14","date_updated":"2023-10-04T08:28:14Z","oa_version":"None","issue":"42","date_published":"2022-10-14T00:00:00Z","publisher":"American Chemical Society","doi":"10.1021/acsami.2c11627","language":[{"iso":"eng"}],"keyword":["General Materials Science"],"article_type":"original","page":"48212-48219","external_id":{"isi":["000873782700001"],"pmid":["36239982"]},"year":"2022","quality_controlled":"1","month":"10","scopus_import":"1","pmid":1,"_id":"12236","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","volume":14,"citation":{"mla":"Wang, Xiang, et al. “CoFeNiMnZnB as a High-Entropy Metal Boride to Boost the Oxygen Evolution Reaction.” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 14, no. 42, American Chemical Society, 2022, pp. 48212–19, doi:<a href=\"https://doi.org/10.1021/acsami.2c11627\">10.1021/acsami.2c11627</a>.","ista":"Wang X, Zuo Y, Horta S, He R, Yang L, Ostovari Moghaddam A, Ibáñez M, Qi X, Cabot A. 2022. CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. ACS Applied Materials &#38; Interfaces. 14(42), 48212–48219.","chicago":"Wang, Xiang, Yong Zuo, Sharona Horta, Ren He, Linlin Yang, Ahmad Ostovari Moghaddam, Maria Ibáñez, Xueqiang Qi, and Andreu Cabot. “CoFeNiMnZnB as a High-Entropy Metal Boride to Boost the Oxygen Evolution Reaction.” <i>ACS Applied Materials &#38; Interfaces</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acsami.2c11627\">https://doi.org/10.1021/acsami.2c11627</a>.","short":"X. Wang, Y. Zuo, S. Horta, R. He, L. Yang, A. Ostovari Moghaddam, M. Ibáñez, X. Qi, A. Cabot, ACS Applied Materials &#38; Interfaces 14 (2022) 48212–48219.","ieee":"X. Wang <i>et al.</i>, “CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction,” <i>ACS Applied Materials &#38; Interfaces</i>, vol. 14, no. 42. American Chemical Society, pp. 48212–48219, 2022.","apa":"Wang, X., Zuo, Y., Horta, S., He, R., Yang, L., Ostovari Moghaddam, A., … Cabot, A. (2022). CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. <i>ACS Applied Materials &#38; Interfaces</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsami.2c11627\">https://doi.org/10.1021/acsami.2c11627</a>","ama":"Wang X, Zuo Y, Horta S, et al. CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. <i>ACS Applied Materials &#38; Interfaces</i>. 2022;14(42):48212-48219. doi:<a href=\"https://doi.org/10.1021/acsami.2c11627\">10.1021/acsami.2c11627</a>"},"publication_status":"published"},{"publication_status":"published","citation":{"short":"N. Hino, K. Matsuda, Y. Jikko, G. Maryu, K. Sakai, R. Imamura, S. Tsukiji, K. Aoki, K. Terai, T. Hirashima, X. Trepat, M. Matsuda, Developmental Cell 57 (2022) 2290–2304.e7.","mla":"Hino, Naoya, et al. “A Feedback Loop between Lamellipodial Extension and HGF-ERK Signaling Specifies Leader Cells during Collective Cell Migration.” <i>Developmental Cell</i>, vol. 57, no. 19, Elsevier, 2022, p. 2290–2304.e7, doi:<a href=\"https://doi.org/10.1016/j.devcel.2022.09.003\">10.1016/j.devcel.2022.09.003</a>.","chicago":"Hino, Naoya, Kimiya Matsuda, Yuya Jikko, Gembu Maryu, Katsuya Sakai, Ryu Imamura, Shinya Tsukiji, et al. “A Feedback Loop between Lamellipodial Extension and HGF-ERK Signaling Specifies Leader Cells during Collective Cell Migration.” <i>Developmental Cell</i>. Elsevier, 2022. <a href=\"https://doi.org/10.1016/j.devcel.2022.09.003\">https://doi.org/10.1016/j.devcel.2022.09.003</a>.","ista":"Hino N, Matsuda K, Jikko Y, Maryu G, Sakai K, Imamura R, Tsukiji S, Aoki K, Terai K, Hirashima T, Trepat X, Matsuda M. 2022. A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration. Developmental Cell. 57(19), 2290–2304.e7.","ama":"Hino N, Matsuda K, Jikko Y, et al. A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration. <i>Developmental Cell</i>. 2022;57(19):2290-2304.e7. doi:<a href=\"https://doi.org/10.1016/j.devcel.2022.09.003\">10.1016/j.devcel.2022.09.003</a>","apa":"Hino, N., Matsuda, K., Jikko, Y., Maryu, G., Sakai, K., Imamura, R., … Matsuda, M. (2022). A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration. <i>Developmental Cell</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.devcel.2022.09.003\">https://doi.org/10.1016/j.devcel.2022.09.003</a>","ieee":"N. Hino <i>et al.</i>, “A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration,” <i>Developmental Cell</i>, vol. 57, no. 19. Elsevier, p. 2290–2304.e7, 2022."},"type":"journal_article","corr_author":"1","volume":57,"OA_place":"publisher","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","_id":"12238","pmid":1,"scopus_import":"1","month":"10","quality_controlled":"1","year":"2022","external_id":{"pmid":["36174555"],"isi":["000898428700006"]},"page":"2290-2304.e7","article_type":"original","keyword":["Developmental Biology","Cell Biology","General Biochemistry","Genetics and Molecular Biology","Molecular Biology"],"oa":1,"date_published":"2022-10-01T00:00:00Z","doi":"10.1016/j.devcel.2022.09.003","language":[{"iso":"eng"}],"publisher":"Elsevier","issue":"19","oa_version":"Published Version","date_updated":"2026-06-18T17:25:21Z","intvolume":"        57","abstract":[{"text":"Upon the initiation of collective cell migration, the cells at the free edge are specified as leader cells; however, the mechanism underlying the leader cell specification remains elusive. Here, we show that lamellipodial extension after the release from mechanical confinement causes sustained extracellular signal-regulated kinase (ERK) activation and underlies the leader cell specification. Live-imaging of Madin-Darby canine kidney (MDCK) cells and mouse epidermis through the use of Förster resonance energy transfer (FRET)-based biosensors showed that leader cells exhibit sustained ERK activation in a hepatocyte growth factor (HGF)-dependent manner. Meanwhile, follower cells exhibit oscillatory ERK activation waves in an epidermal growth factor (EGF) signaling-dependent manner. Lamellipodial extension at the free edge increases the cellular sensitivity to HGF. The HGF-dependent ERK activation, in turn, promotes lamellipodial extension, thereby forming a positive feedback loop between cell extension and ERK activation and specifying the cells at the free edge as the leader cells. Our findings show that the integration of physical and biochemical cues underlies the leader cell specification during collective cell migration.","lang":"eng"}],"author":[{"id":"5299a9ce-7679-11eb-a7bc-d1e62b936307","first_name":"Naoya","full_name":"Hino, Naoya","last_name":"Hino"},{"first_name":"Kimiya","last_name":"Matsuda","full_name":"Matsuda, Kimiya"},{"full_name":"Jikko, Yuya","last_name":"Jikko","first_name":"Yuya"},{"last_name":"Maryu","full_name":"Maryu, Gembu","first_name":"Gembu"},{"first_name":"Katsuya","full_name":"Sakai, Katsuya","last_name":"Sakai"},{"last_name":"Imamura","full_name":"Imamura, Ryu","first_name":"Ryu"},{"first_name":"Shinya","full_name":"Tsukiji, Shinya","last_name":"Tsukiji"},{"first_name":"Kazuhiro","full_name":"Aoki, Kazuhiro","last_name":"Aoki"},{"first_name":"Kenta","last_name":"Terai","full_name":"Terai, Kenta"},{"first_name":"Tsuyoshi","full_name":"Hirashima, Tsuyoshi","last_name":"Hirashima"},{"first_name":"Xavier","full_name":"Trepat, Xavier","last_name":"Trepat"},{"first_name":"Michiyuki","last_name":"Matsuda","full_name":"Matsuda, Michiyuki"}],"OA_type":"free access","isi":1,"department":[{"_id":"CaHe"}],"title":"A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration","ddc":["570"],"day":"01","publication":"Developmental Cell","publication_identifier":{"issn":["1534-5807"]},"article_processing_charge":"No","main_file_link":[{"url":"https://doi.org/10.1016/j.devcel.2022.09.003","open_access":"1"}],"date_created":"2023-01-16T09:51:39Z","status":"public","acknowledgement":"We thank the members of the Matsuda Laboratory for their helpful discussion and encouragement, and we thank K. Hirano and K. Takakura for their technical assistance. This work was supported by the Kyoto University Live Imaging Center. Financial support was provided in the form of JSPS KAKENHI grants (nos. 17J02107 and 20K22653 to N.H., and 20H05898 and 19H00993 to M.M.), a JST CREST grant (no. JPMJCR1654 to M.M.), a Moonshot R&D grant (no. JPMJPS2022-11 to M.M.), Generalitat de Catalunya and the CERCA Programme (no. SGR-2017-01602 to X.T.), MICCINN/FEDER (no. PGC2018-099645-B-I00 to X.T.), and European Research Council (no. Adv-883739 to X.T.). IBEC is a recipient of a Severo Ochoa Award of Excellence from the MINECO. This work was partly supported by an Extramural Collaborative Research Grant of Cancer Research Institute, Kanazawa University."},{"acknowledgement":"A.J. is supported by funding from the Austrian Science Fund I3630B25 (to J.F.). This research was supported by the Scientific Service Units of Institute of Science and Technology Austria (ISTA) through resources provided by the Electron Microscopy Facility, Lab Support Facility, and the Imaging and Optics Facility. We acknowledge Prof. David Robinson (Heidelberg) and Prof. Jan Traas (Lyon) for making us aware of previously published classical on-grid preparation methods. No conflict of interest declared.","date_created":"2023-01-16T09:51:49Z","status":"public","file_date_updated":"2023-01-30T07:46:51Z","article_processing_charge":"Yes (via OA deal)","publication_identifier":{"issn":["1674-2052"]},"acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"LifeSc"},{"_id":"Bio"}],"publication":"Molecular Plant","ddc":["580"],"day":"03","title":"Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution","department":[{"_id":"JiFr"},{"_id":"EM-Fac"},{"_id":"Bio"}],"project":[{"name":"Molecular mechanisms of endocytic cargo recognition in plants","call_identifier":"FWF","grant_number":"I03630","_id":"26538374-B435-11E9-9278-68D0E5697425"}],"isi":1,"has_accepted_license":"1","author":[{"orcid":"0000-0002-2739-8843","first_name":"Alexander J","id":"46A62C3A-F248-11E8-B48F-1D18A9856A87","full_name":"Johnson, Alexander J","last_name":"Johnson"},{"orcid":"0000-0001-9735-5315","first_name":"Walter","id":"3F99E422-F248-11E8-B48F-1D18A9856A87","full_name":"Kaufmann, Walter","last_name":"Kaufmann"},{"first_name":"Christoph M","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1216-9105","last_name":"Sommer","full_name":"Sommer, Christoph M"},{"last_name":"Costanzo","full_name":"Costanzo, Tommaso","id":"D93824F4-D9BA-11E9-BB12-F207E6697425","first_name":"Tommaso","orcid":"0000-0001-9732-3815"},{"full_name":"Dahhan, Dana A.","last_name":"Dahhan","first_name":"Dana A."},{"first_name":"Sebastian Y.","last_name":"Bednarek","full_name":"Bednarek, Sebastian Y."},{"last_name":"Friml","full_name":"Friml, Jiří","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596"}],"abstract":[{"lang":"eng","text":"Biological systems are the sum of their dynamic three-dimensional (3D) parts. Therefore, it is critical to study biological structures in 3D and at high resolution to gain insights into their physiological functions. Electron microscopy of metal replicas of unroofed cells and isolated organelles has been a key technique to visualize intracellular structures at nanometer resolution. However, many of these methods require specialized equipment and personnel to complete them. Here, we present novel accessible methods to analyze biological structures in unroofed cells and biochemically isolated organelles in 3D and at nanometer resolution, focusing on Arabidopsis clathrin-coated vesicles (CCVs). While CCVs are essential trafficking organelles, their detailed structural information is lacking due to their poor preservation when observed via classical electron microscopy protocols experiments. First, we establish a method to visualize CCVs in unroofed cells using scanning transmission electron microscopy tomography, providing sufficient resolution to define the clathrin coat arrangements. Critically, the samples are prepared directly on electron microscopy grids, removing the requirement to use extremely corrosive acids, thereby enabling the use of this method in any electron microscopy lab. Secondly, we demonstrate that this standardized sample preparation allows the direct comparison of isolated CCV samples with those visualized in cells. Finally, to facilitate the high-throughput and robust screening of metal replicated samples, we provide a deep learning analysis method to screen the “pseudo 3D” morphologies of CCVs imaged with 2D modalities. Collectively, our work establishes accessible ways to examine the 3D structure of biological samples and provide novel insights into the structure of plant CCVs."}],"oa_version":"Published Version","intvolume":"        15","date_updated":"2025-04-15T07:32:09Z","date_published":"2022-10-03T00:00:00Z","publisher":"Elsevier","language":[{"iso":"eng"}],"doi":"10.1016/j.molp.2022.09.003","issue":"10","file":[{"success":1,"relation":"main_file","creator":"dernst","date_created":"2023-01-30T07:46:51Z","file_size":2307251,"date_updated":"2023-01-30T07:46:51Z","content_type":"application/pdf","access_level":"open_access","checksum":"04d5c12490052d03e4dc4412338a43dd","file_name":"2022_MolecularPlant_Johnson.pdf","file_id":"12435"}],"oa":1,"keyword":["Plant Science","Molecular Biology"],"article_type":"original","page":"1533-1542","external_id":{"isi":["000882769800009"],"pmid":["36081349"]},"quality_controlled":"1","year":"2022","pmid":1,"scopus_import":"1","month":"10","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"12239","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","type":"journal_article","corr_author":"1","volume":15,"publication_status":"published","citation":{"short":"A.J. Johnson, W. Kaufmann, C.M. Sommer, T. Costanzo, D.A. Dahhan, S.Y. Bednarek, J. Friml, Molecular Plant 15 (2022) 1533–1542.","mla":"Johnson, Alexander J., et al. “Three-Dimensional Visualization of Planta Clathrin-Coated Vesicles at Ultrastructural Resolution.” <i>Molecular Plant</i>, vol. 15, no. 10, Elsevier, 2022, pp. 1533–42, doi:<a href=\"https://doi.org/10.1016/j.molp.2022.09.003\">10.1016/j.molp.2022.09.003</a>.","ista":"Johnson AJ, Kaufmann W, Sommer CM, Costanzo T, Dahhan DA, Bednarek SY, Friml J. 2022. Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution. Molecular Plant. 15(10), 1533–1542.","chicago":"Johnson, Alexander J, Walter Kaufmann, Christoph M Sommer, Tommaso Costanzo, Dana A. Dahhan, Sebastian Y. Bednarek, and Jiří Friml. “Three-Dimensional Visualization of Planta Clathrin-Coated Vesicles at Ultrastructural Resolution.” <i>Molecular Plant</i>. Elsevier, 2022. <a href=\"https://doi.org/10.1016/j.molp.2022.09.003\">https://doi.org/10.1016/j.molp.2022.09.003</a>.","apa":"Johnson, A. J., Kaufmann, W., Sommer, C. M., Costanzo, T., Dahhan, D. A., Bednarek, S. Y., &#38; Friml, J. (2022). Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution. <i>Molecular Plant</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.molp.2022.09.003\">https://doi.org/10.1016/j.molp.2022.09.003</a>","ama":"Johnson AJ, Kaufmann W, Sommer CM, et al. Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution. <i>Molecular Plant</i>. 2022;15(10):1533-1542. doi:<a href=\"https://doi.org/10.1016/j.molp.2022.09.003\">10.1016/j.molp.2022.09.003</a>","ieee":"A. J. Johnson <i>et al.</i>, “Three-dimensional visualization of planta clathrin-coated vesicles at ultrastructural resolution,” <i>Molecular Plant</i>, vol. 15, no. 10. Elsevier, pp. 1533–1542, 2022."}},{"abstract":[{"text":"We consider the eigenvalues of a large dimensional real or complex Ginibre matrix in the region of the complex plane where their real parts reach their maximum value. This maximum follows the Gumbel distribution and that these extreme eigenvalues form a Poisson point process as the dimension asymptotically tends to infinity. In the complex case, these facts have already been established by Bender [Probab. Theory Relat. Fields 147, 241 (2010)] and in the real case by Akemann and Phillips [J. Stat. Phys. 155, 421 (2014)] even for the more general elliptic ensemble with a sophisticated saddle point analysis. The purpose of this article is to give a very short direct proof in the Ginibre case with an effective error term. Moreover, our estimates on the correlation kernel in this regime serve as a key input for accurately locating [Formula: see text] for any large matrix X with i.i.d. entries in the companion paper [G. Cipolloni et al., arXiv:2206.04448 (2022)]. ","lang":"eng"}],"intvolume":"        63","date_updated":"2025-04-14T07:57:18Z","article_number":"103303","oa_version":"Published Version","author":[{"full_name":"Cipolloni, Giorgio","last_name":"Cipolloni","orcid":"0000-0002-4901-7992","id":"42198EFA-F248-11E8-B48F-1D18A9856A87","first_name":"Giorgio"},{"first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","last_name":"Erdös","full_name":"Erdös, László"},{"full_name":"Schröder, Dominik J","last_name":"Schröder","orcid":"0000-0002-2904-1856","first_name":"Dominik J","id":"408ED176-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0003-1559-1205","id":"7902bdb1-a2a4-11eb-a164-c9216f71aea3","first_name":"Yuanyuan","full_name":"Xu, Yuanyuan","last_name":"Xu"}],"project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","grant_number":"101020331","call_identifier":"H2020","name":"Random matrices beyond Wigner-Dyson-Mehta"}],"department":[{"_id":"LaEr"}],"has_accepted_license":"1","isi":1,"day":"14","ddc":["510","530"],"title":"Directional extremal statistics for Ginibre eigenvalues","publication":"Journal of Mathematical Physics","publication_identifier":{"eissn":["1089-7658"],"issn":["0022-2488"]},"ec_funded":1,"article_processing_charge":"Yes (via OA deal)","acknowledgement":"The authors are grateful to G. Akemann for bringing Refs. 19 and 24–26 to their attention. Discussions with Guillaume Dubach on a preliminary version of this project are acknowledged.\r\nL.E. and Y.X. were supported by the ERC Advanced Grant “RMTBeyond” under Grant No. 101020331. D.S. was supported by Dr. Max Rössler, the Walter Haefner Foundation, and the ETH Zürich Foundation.","status":"public","file_date_updated":"2023-01-30T08:01:10Z","date_created":"2023-01-16T09:52:58Z","type":"journal_article","volume":63,"citation":{"apa":"Cipolloni, G., Erdös, L., Schröder, D. J., &#38; Xu, Y. (2022). Directional extremal statistics for Ginibre eigenvalues. <i>Journal of Mathematical Physics</i>. AIP Publishing. <a href=\"https://doi.org/10.1063/5.0104290\">https://doi.org/10.1063/5.0104290</a>","ama":"Cipolloni G, Erdös L, Schröder DJ, Xu Y. Directional extremal statistics for Ginibre eigenvalues. <i>Journal of Mathematical Physics</i>. 2022;63(10). doi:<a href=\"https://doi.org/10.1063/5.0104290\">10.1063/5.0104290</a>","ieee":"G. Cipolloni, L. Erdös, D. J. Schröder, and Y. Xu, “Directional extremal statistics for Ginibre eigenvalues,” <i>Journal of Mathematical Physics</i>, vol. 63, no. 10. AIP Publishing, 2022.","chicago":"Cipolloni, Giorgio, László Erdös, Dominik J Schröder, and Yuanyuan Xu. “Directional Extremal Statistics for Ginibre Eigenvalues.” <i>Journal of Mathematical Physics</i>. AIP Publishing, 2022. <a href=\"https://doi.org/10.1063/5.0104290\">https://doi.org/10.1063/5.0104290</a>.","mla":"Cipolloni, Giorgio, et al. “Directional Extremal Statistics for Ginibre Eigenvalues.” <i>Journal of Mathematical Physics</i>, vol. 63, no. 10, 103303, AIP Publishing, 2022, doi:<a href=\"https://doi.org/10.1063/5.0104290\">10.1063/5.0104290</a>.","ista":"Cipolloni G, Erdös L, Schröder DJ, Xu Y. 2022. Directional extremal statistics for Ginibre eigenvalues. Journal of Mathematical Physics. 63(10), 103303.","short":"G. Cipolloni, L. Erdös, D.J. Schröder, Y. Xu, Journal of Mathematical Physics 63 (2022)."},"publication_status":"published","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"_id":"12243","scopus_import":"1","month":"10","arxiv":1,"year":"2022","quality_controlled":"1","external_id":{"arxiv":["2206.04443"],"isi":["000869715800001"]},"keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"article_type":"original","issue":"10","date_published":"2022-10-14T00:00:00Z","doi":"10.1063/5.0104290","publisher":"AIP Publishing","language":[{"iso":"eng"}],"oa":1,"file":[{"date_updated":"2023-01-30T08:01:10Z","content_type":"application/pdf","file_size":7356807,"file_id":"12436","access_level":"open_access","checksum":"2db278ae5b07f345a7e3fec1f92b5c33","file_name":"2022_JourMathPhysics_Cipolloni2.pdf","creator":"dernst","relation":"main_file","success":1,"date_created":"2023-01-30T08:01:10Z"}]},{"external_id":{"isi":["000918161000003"],"pmid":["36189829"]},"year":"2022","quality_controlled":"1","issue":"19","language":[{"iso":"eng"}],"doi":"10.1242/dev.200474","date_published":"2022-10-01T00:00:00Z","publisher":"The Company of Biologists","oa":1,"file":[{"content_type":"application/pdf","date_updated":"2023-01-30T08:35:44Z","file_size":9348839,"file_id":"12438","file_name":"2022_Development_Soto.pdf","checksum":"d7c29b74e9e4032308228cc704a30e88","access_level":"open_access","creator":"dernst","relation":"main_file","success":1,"date_created":"2023-01-30T08:35:44Z"}],"keyword":["Developmental Biology","Molecular Biology"],"article_type":"original","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","volume":149,"type":"journal_article","citation":{"ieee":"X. Soto <i>et al.</i>, “Sequential and additive expression of miR-9 precursors control timing of neurogenesis,” <i>Development</i>, vol. 149, no. 19. The Company of Biologists, 2022.","ama":"Soto X, Burton J, Manning CS, et al. Sequential and additive expression of miR-9 precursors control timing of neurogenesis. <i>Development</i>. 2022;149(19). doi:<a href=\"https://doi.org/10.1242/dev.200474\">10.1242/dev.200474</a>","apa":"Soto, X., Burton, J., Manning, C. S., Minchington, T., Lea, R., Lee, J., … Papalopulu, N. (2022). Sequential and additive expression of miR-9 precursors control timing of neurogenesis. <i>Development</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/dev.200474\">https://doi.org/10.1242/dev.200474</a>","chicago":"Soto, Ximena, Joshua Burton, Cerys S. Manning, Thomas Minchington, Robert Lea, Jessica Lee, Jochen Kursawe, Magnus Rattray, and Nancy Papalopulu. “Sequential and Additive Expression of MiR-9 Precursors Control Timing of Neurogenesis.” <i>Development</i>. The Company of Biologists, 2022. <a href=\"https://doi.org/10.1242/dev.200474\">https://doi.org/10.1242/dev.200474</a>.","mla":"Soto, Ximena, et al. “Sequential and Additive Expression of MiR-9 Precursors Control Timing of Neurogenesis.” <i>Development</i>, vol. 149, no. 19, dev200474, The Company of Biologists, 2022, doi:<a href=\"https://doi.org/10.1242/dev.200474\">10.1242/dev.200474</a>.","ista":"Soto X, Burton J, Manning CS, Minchington T, Lea R, Lee J, Kursawe J, Rattray M, Papalopulu N. 2022. Sequential and additive expression of miR-9 precursors control timing of neurogenesis. Development. 149(19), dev200474.","short":"X. Soto, J. Burton, C.S. Manning, T. Minchington, R. Lea, J. Lee, J. Kursawe, M. Rattray, N. Papalopulu, Development 149 (2022)."},"publication_status":"published","month":"10","scopus_import":"1","pmid":1,"_id":"12245","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png"},"publication_identifier":{"eissn":["1477-9129"],"issn":["0950-1991"]},"related_material":{"link":[{"url":" https://github.com/burtonjosh/StepwiseMir9","relation":"software"}]},"publication":"Development","acknowledgement":"We are grateful to Dr Tom Pettini for the advice on smiFISH technique and Dr Laure Bally-Cuif for sharing plasmids. The authors also thank the Biological Services Facility, Bioimaging and Systems Microscopy Facilities of the University of Manchester for technical support.\r\nThis work was supported by a Wellcome Trust Senior Research Fellowship (090868/Z/09/Z) and a Wellcome Trust Investigator Award (224394/Z/21/Z) to N.P. and a Medical Research Council Career Development Award to C.S.M. (MR/V032534/1). J.B. was supported by a Wellcome Trust Four-Year PhD Studentship in Basic Science (219992/Z/19/Z). Open Access funding provided by The University of Manchester. Deposited in PMC for immediate release.","status":"public","file_date_updated":"2023-01-30T08:35:44Z","date_created":"2023-01-16T09:53:17Z","article_processing_charge":"No","author":[{"last_name":"Soto","full_name":"Soto, Ximena","first_name":"Ximena"},{"first_name":"Joshua","full_name":"Burton, Joshua","last_name":"Burton"},{"full_name":"Manning, Cerys S.","last_name":"Manning","first_name":"Cerys S."},{"full_name":"Minchington, Thomas","last_name":"Minchington","first_name":"Thomas","id":"7d1648cb-19e9-11eb-8e7a-f8c037fb3e3f"},{"last_name":"Lea","full_name":"Lea, Robert","first_name":"Robert"},{"first_name":"Jessica","last_name":"Lee","full_name":"Lee, Jessica"},{"first_name":"Jochen","full_name":"Kursawe, Jochen","last_name":"Kursawe"},{"last_name":"Rattray","full_name":"Rattray, Magnus","first_name":"Magnus"},{"full_name":"Papalopulu, Nancy","last_name":"Papalopulu","first_name":"Nancy"}],"abstract":[{"text":"MicroRNAs (miRs) have an important role in tuning dynamic gene expression. However, the mechanism by which they are quantitatively controlled is unknown. We show that the amount of mature miR-9, a key regulator of neuronal development, increases during zebrafish neurogenesis in a sharp stepwise manner. We characterize the spatiotemporal profile of seven distinct microRNA primary transcripts (pri-mir)-9s that produce the same mature miR-9 and show that they are sequentially expressed during hindbrain neurogenesis. Expression of late-onset pri-mir-9-1 is added on to, rather than replacing, the expression of early onset pri-mir-9-4 and -9-5 in single cells. CRISPR/Cas9 mutation of the late-onset pri-mir-9-1 prevents the developmental increase of mature miR-9, reduces late neuronal differentiation and fails to downregulate Her6 at late stages. Mathematical modelling shows that an adaptive network containing Her6 is insensitive to linear increases in miR-9 but responds to stepwise increases of miR-9. We suggest that a sharp stepwise increase of mature miR-9 is created by sequential and additive temporal activation of distinct loci. This may be a strategy to overcome adaptation and facilitate a transition of Her6 to a new dynamic regime or steady state.","lang":"eng"}],"date_updated":"2023-08-04T09:41:08Z","intvolume":"       149","oa_version":"Published Version","article_number":"dev200474","day":"01","ddc":["570"],"title":"Sequential and additive expression of miR-9 precursors control timing of neurogenesis","department":[{"_id":"AnKi"}],"isi":1,"has_accepted_license":"1"},{"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","citation":{"ieee":"M. Lewin, E. H. Lieb, and R. Seiringer, “Improved Lieb–Oxford bound on the indirect and exchange energies,” <i>Letters in Mathematical Physics</i>, vol. 112, no. 5. Springer Nature, 2022.","apa":"Lewin, M., Lieb, E. H., &#38; Seiringer, R. (2022). Improved Lieb–Oxford bound on the indirect and exchange energies. <i>Letters in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11005-022-01584-5\">https://doi.org/10.1007/s11005-022-01584-5</a>","ama":"Lewin M, Lieb EH, Seiringer R. Improved Lieb–Oxford bound on the indirect and exchange energies. <i>Letters in Mathematical Physics</i>. 2022;112(5). doi:<a href=\"https://doi.org/10.1007/s11005-022-01584-5\">10.1007/s11005-022-01584-5</a>","short":"M. Lewin, E.H. Lieb, R. Seiringer, Letters in Mathematical Physics 112 (2022).","mla":"Lewin, Mathieu, et al. “Improved Lieb–Oxford Bound on the Indirect and Exchange Energies.” <i>Letters in Mathematical Physics</i>, vol. 112, no. 5, 92, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s11005-022-01584-5\">10.1007/s11005-022-01584-5</a>.","ista":"Lewin M, Lieb EH, Seiringer R. 2022. Improved Lieb–Oxford bound on the indirect and exchange energies. Letters in Mathematical Physics. 112(5), 92.","chicago":"Lewin, Mathieu, Elliott H. Lieb, and Robert Seiringer. “Improved Lieb–Oxford Bound on the Indirect and Exchange Energies.” <i>Letters in Mathematical Physics</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s11005-022-01584-5\">https://doi.org/10.1007/s11005-022-01584-5</a>."},"publication_status":"published","volume":112,"type":"journal_article","arxiv":1,"month":"09","scopus_import":"1","_id":"12246","external_id":{"isi":["000854762600001"],"arxiv":["2203.12473"]},"year":"2022","quality_controlled":"1","oa":1,"issue":"5","date_published":"2022-09-15T00:00:00Z","publisher":"Springer Nature","doi":"10.1007/s11005-022-01584-5","language":[{"iso":"eng"}],"article_type":"original","keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"author":[{"full_name":"Lewin, Mathieu","last_name":"Lewin","first_name":"Mathieu"},{"first_name":"Elliott H.","last_name":"Lieb","full_name":"Lieb, Elliott H."},{"last_name":"Seiringer","full_name":"Seiringer, Robert","first_name":"Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521"}],"date_updated":"2025-04-14T07:26:59Z","intvolume":"       112","article_number":"92","oa_version":"Preprint","abstract":[{"lang":"eng","text":"The Lieb–Oxford inequality provides a lower bound on the Coulomb energy of a classical system of N identical charges only in terms of their one-particle density. We prove here a new estimate on the best constant in this inequality. Numerical evaluation provides the value 1.58, which is a significant improvement to the previously known value 1.64. The best constant has recently been shown to be larger than 1.44. In a second part, we prove that the constant can be reduced to 1.25 when the inequality is restricted to Hartree–Fock states. This is the first proof that the exchange term is always much lower than the full indirect Coulomb energy."}],"title":"Improved Lieb–Oxford bound on the indirect and exchange energies","day":"15","isi":1,"project":[{"name":"Analysis of quantum many-body systems","call_identifier":"H2020","grant_number":"694227","_id":"25C6DC12-B435-11E9-9278-68D0E5697425"}],"department":[{"_id":"RoSe"}],"ec_funded":1,"publication_identifier":{"issn":["0377-9017"],"eissn":["1573-0530"]},"publication":"Letters in Mathematical Physics","status":"public","date_created":"2023-01-16T09:53:54Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2203.12473"}],"acknowledgement":"We would like to thank David Gontier for useful advice on the numerical simulations. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant Agreements MDFT No. 725528 of M.L. and AQUAMS No. 694227 of R.S.). We are thankful for the hospitality of the Institut Henri Poincaré in Paris, where part of this work was done.","article_processing_charge":"No"}]