[{"volume":18,"abstract":[{"text":"This workshop continued a biannual series of workshops at Oberwolfach on dynamical systems that started with a meeting organized by Moser and Zehnder in 1981. Workshops in this series focus on new results and developments in dynamical systems and related areas of mathematics, with symplectic geometry playing an important role in recent years in connection with Hamiltonian dynamics. In this year special emphasis was placed on various kinds of spectra (in contact geometry, in Riemannian geometry, in dynamical systems and in symplectic topology) and their applications to dynamics.","lang":"eng"}],"article_type":"original","day":"26","scopus_import":"1","publication":"Oberwolfach Reports","ddc":["500"],"page":"1735-1803","language":[{"iso":"eng"}],"issue":"3","oa_version":"Published Version","citation":{"ieee":"M.-C. Arnaud, H. W. Hofer, M. Hutchings, and V. Kaloshin, “Dynamische Systeme,” <i>Oberwolfach Reports</i>, vol. 18, no. 3. EMS Press, pp. 1735–1803, 2022.","chicago":"Arnaud, Marie-Claude, Helmut W. Hofer, Michael Hutchings, and Vadim Kaloshin. “Dynamische Systeme.” <i>Oberwolfach Reports</i>. EMS Press, 2022. <a href=\"https://doi.org/10.4171/owr/2021/33\">https://doi.org/10.4171/owr/2021/33</a>.","short":"M.-C. Arnaud, H.W. Hofer, M. Hutchings, V. Kaloshin, Oberwolfach Reports 18 (2022) 1735–1803.","apa":"Arnaud, M.-C., Hofer, H. W., Hutchings, M., &#38; Kaloshin, V. (2022). Dynamische Systeme. <i>Oberwolfach Reports</i>. EMS Press. <a href=\"https://doi.org/10.4171/owr/2021/33\">https://doi.org/10.4171/owr/2021/33</a>","mla":"Arnaud, Marie-Claude, et al. “Dynamische Systeme.” <i>Oberwolfach Reports</i>, vol. 18, no. 3, EMS Press, 2022, pp. 1735–803, doi:<a href=\"https://doi.org/10.4171/owr/2021/33\">10.4171/owr/2021/33</a>.","ista":"Arnaud M-C, Hofer HW, Hutchings M, Kaloshin V. 2022. Dynamische Systeme. Oberwolfach Reports. 18(3), 1735–1803.","ama":"Arnaud M-C, Hofer HW, Hutchings M, Kaloshin V. Dynamische Systeme. <i>Oberwolfach Reports</i>. 2022;18(3):1735-1803. doi:<a href=\"https://doi.org/10.4171/owr/2021/33\">10.4171/owr/2021/33</a>"},"publication_identifier":{"issn":["1660-8933"],"eissn":["1660-8941"]},"doi":"10.4171/owr/2021/33","date_updated":"2026-07-06T11:52:32Z","year":"2022","title":"Dynamische Systeme","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","_id":"17063","publisher":"EMS Press","intvolume":"        18","oa":1,"author":[{"last_name":"Arnaud","full_name":"Arnaud, Marie-Claude","first_name":"Marie-Claude"},{"first_name":"Helmut W.","full_name":"Hofer, Helmut W.","last_name":"Hofer"},{"first_name":"Michael","last_name":"Hutchings","full_name":"Hutchings, Michael"},{"orcid":"0000-0002-6051-2628","id":"FE553552-CDE8-11E9-B324-C0EBE5697425","first_name":"Vadim","full_name":"Kaloshin, Vadim","last_name":"Kaloshin"}],"corr_author":"1","das_tickbox":"1","fulldoi":"https://doi.org/10.4171/owr/2021/33","type":"journal_article","date_published":"2022-11-26T00:00:00Z","date_created":"2024-05-29T06:01:19Z","department":[{"_id":"VaKa"}],"month":"11","article_processing_charge":"No","main_file_link":[{"url":"https://www.doi.org/10.4171/OWR/2021/33","open_access":"1"}],"publication_status":"published"},{"abstract":[{"lang":"eng","text":"SnSe has emerged as one of the most promising materials for thermoelectric energy conversion due to its extraordinary performance in its single-crystal form and its low-cost constituent elements. However, to achieve an economic impact, the polycrystalline counterpart needs to replicate the performance of the single crystal. Herein, we optimize the thermoelectric performance of polycrystalline SnSe produced by consolidating solution-processed and surface-engineered SnSe particles. In particular, the SnSe particles are coated with CdSe molecular complexes that crystallize during the sintering process, forming CdSe nanoparticles. The presence of CdSe nanoparticles inhibits SnSe grain growth during the consolidation step due to Zener pinning, yielding a material with a high density of grain boundaries. Moreover, the resulting SnSe–CdSe nanocomposites present a large number of defects at different length scales, which significantly reduce the thermal conductivity. The produced SnSe–CdSe nanocomposites exhibit thermoelectric figures of merit up to 2.2 at 786 K, which is among the highest reported for solution-processed SnSe."}],"volume":16,"scopus_import":"1","day":"25","article_type":"original","project":[{"call_identifier":"H2020","grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program"},{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"},{"name":"Bottom-up Engineering for Thermoelectric Applications","grant_number":"M02889","_id":"9B8804FC-BA93-11EA-9121-9846C619BF3A"}],"ddc":["540"],"publication":"ACS Nano","page":"78-88","ec_funded":1,"language":[{"iso":"eng"}],"acknowledgement":"This work was financially supported by IST Austria and the Werner Siemens Foundation. Y.L. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411. S.L. and M.C. received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 665385. J.D. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement no. 665919 (P-SPHERE) cofunded by Severo Ochoa Programme. C.C. acknowledges funding from the FWF “Lise Meitner Fellowship” grant agreement M 2889-N. Y.Y. and O.C.-M. acknowledge the financial support from DFG within the project SFB 917: Nanoswitches. M.C.S. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 754510 (PROBIST) and the Severo Ochoa programme. J.D. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 665919 (P-SPHERE) cofunded by Severo Ochoa Programme. The ICN2 is funded by the CERCA Program/Generalitat de Catalunya and by the Severo Ochoa program of the Spanish Ministry of Economy, Industry, and Competitiveness (MINECO, grant no. SEV-2017-0706). ICN2 acknowledges funding from Generalitat de Catalunya 2017 SGR 327 and the Spanish MINECO project NANOGEN (PID2020-116093RB-C43). This project received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No. 823717-ESTEEM3. The FIB sample preparation was conducted in the LMA-INA-Universidad de Zaragoza.","issue":"1","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"citation":{"apa":"Liu, Y., Calcabrini, M., Yu, Y., Lee, S., Chang, C., David, J., … Ibáñez, M. (2022). Defect engineering in solution-processed polycrystalline SnSe leads to high thermoelectric performance. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.1c06720\">https://doi.org/10.1021/acsnano.1c06720</a>","short":"Y. Liu, M. Calcabrini, Y. Yu, S. Lee, C. Chang, J. David, T. Ghosh, M.C. Spadaro, C. Xie, O. Cojocaru-Mirédin, J. Arbiol, M. Ibáñez, ACS Nano 16 (2022) 78–88.","ieee":"Y. Liu <i>et al.</i>, “Defect engineering in solution-processed polycrystalline SnSe leads to high thermoelectric performance,” <i>ACS Nano</i>, vol. 16, no. 1. American Chemical Society, pp. 78–88, 2022.","chicago":"Liu, Yu, Mariano Calcabrini, Yuan Yu, Seungho Lee, Cheng Chang, Jérémy David, Tanmoy Ghosh, et al. “Defect Engineering in Solution-Processed Polycrystalline SnSe Leads to High Thermoelectric Performance.” <i>ACS Nano</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acsnano.1c06720\">https://doi.org/10.1021/acsnano.1c06720</a>.","ama":"Liu Y, Calcabrini M, Yu Y, et al. Defect engineering in solution-processed polycrystalline SnSe leads to high thermoelectric performance. <i>ACS Nano</i>. 2022;16(1):78-88. doi:<a href=\"https://doi.org/10.1021/acsnano.1c06720\">10.1021/acsnano.1c06720</a>","ista":"Liu Y, Calcabrini M, Yu Y, Lee S, Chang C, David J, Ghosh T, Spadaro MC, Xie C, Cojocaru-Mirédin O, Arbiol J, Ibáñez M. 2022. Defect engineering in solution-processed polycrystalline SnSe leads to high thermoelectric performance. ACS Nano. 16(1), 78–88.","mla":"Liu, Yu, et al. “Defect Engineering in Solution-Processed Polycrystalline SnSe Leads to High Thermoelectric Performance.” <i>ACS Nano</i>, vol. 16, no. 1, American Chemical Society, 2022, pp. 78–88, doi:<a href=\"https://doi.org/10.1021/acsnano.1c06720\">10.1021/acsnano.1c06720</a>."},"keyword":["tin selenide","nanocomposite","grain growth","Zener pinning","thermoelectricity","annealing","solution processing"],"publication_identifier":{"issn":["1936-0851"],"eissn":["1936-086X"]},"file":[{"content_type":"application/pdf","checksum":"74f9c1aa5f95c0b992a4328e8e0247b4","file_name":"2022_ACSNano_Liu.pdf","date_created":"2022-03-02T16:17:29Z","relation":"main_file","file_id":"10808","file_size":9050764,"creator":"cchlebak","success":1,"access_level":"open_access","date_updated":"2022-03-02T16:17:29Z"}],"file_date_updated":"2022-03-02T16:17:29Z","date_updated":"2026-07-06T12:16:06Z","year":"2022","title":"Defect engineering in solution-processed polycrystalline SnSe leads to high thermoelectric performance","doi":"10.1021/acsnano.1c06720","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","has_accepted_license":"1","isi":1,"_id":"10042","intvolume":"        16","publisher":"American Chemical Society","oa":1,"corr_author":"1","author":[{"first_name":"Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7313-6740","last_name":"Liu","full_name":"Liu, Yu"},{"last_name":"Calcabrini","full_name":"Calcabrini, Mariano","id":"45D7531A-F248-11E8-B48F-1D18A9856A87","first_name":"Mariano","orcid":"0000-0003-4566-5877"},{"first_name":"Yuan","full_name":"Yu, Yuan","last_name":"Yu"},{"last_name":"Lee","full_name":"Lee, Seungho","first_name":"Seungho","id":"BB243B88-D767-11E9-B658-BC13E6697425","orcid":"0000-0002-6962-8598"},{"last_name":"Chang","full_name":"Chang, Cheng","id":"9E331C2E-9F27-11E9-AE48-5033E6697425","first_name":"Cheng","orcid":"0000-0002-9515-4277"},{"full_name":"David, Jérémy","last_name":"David","first_name":"Jérémy"},{"last_name":"Ghosh","full_name":"Ghosh, Tanmoy","id":"a5fc9bc3-feff-11ea-93fe-e8015a3c7e9d","first_name":"Tanmoy"},{"first_name":"Maria Chiara","full_name":"Spadaro, Maria Chiara","last_name":"Spadaro"},{"full_name":"Xie, Chenyang","last_name":"Xie","first_name":"Chenyang"},{"full_name":"Cojocaru-Mirédin, Oana","last_name":"Cojocaru-Mirédin","first_name":"Oana"},{"full_name":"Arbiol, Jordi","last_name":"Arbiol","first_name":"Jordi"},{"id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","orcid":"0000-0001-5013-2843","last_name":"Ibáñez","full_name":"Ibáñez, Maria"}],"das_tickbox":"1","fulldoi":"https://doi.org/10.1021/acsnano.1c06720","date_published":"2022-01-25T00:00:00Z","type":"journal_article","pmid":1,"related_material":{"record":[{"id":"12885","relation":"dissertation_contains","status":"public"}]},"date_created":"2021-09-24T07:55:12Z","external_id":{"isi":["000767223400008"],"pmid":["34549956"]},"article_processing_charge":"Yes (via OA deal)","month":"01","department":[{"_id":"MaIb"}],"publication_status":"published"},{"publisher":"National Academy of Sciences","intvolume":"       119","author":[{"first_name":"Jana","id":"30F3F2F0-F248-11E8-B48F-1D18A9856A87","full_name":"Slovakova, Jana","last_name":"Slovakova"},{"full_name":"Sikora, Mateusz K","last_name":"Sikora","id":"2F74BCDE-F248-11E8-B48F-1D18A9856A87","first_name":"Mateusz K"},{"last_name":"Arslan","full_name":"Arslan, Feyza N","first_name":"Feyza N","id":"49DA7910-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5809-9566"},{"orcid":"0000-0002-5223-3346","first_name":"Silvia","id":"2F1E1758-F248-11E8-B48F-1D18A9856A87","full_name":"Caballero Mancebo, Silvia","last_name":"Caballero Mancebo"},{"last_name":"Krens","full_name":"Krens, Gabriel","id":"2B819732-F248-11E8-B48F-1D18A9856A87","first_name":"Gabriel","orcid":"0000-0003-4761-5996"},{"orcid":"0000-0001-9735-5315","first_name":"Walter","id":"3F99E422-F248-11E8-B48F-1D18A9856A87","full_name":"Kaufmann, Walter","last_name":"Kaufmann"},{"last_name":"Merrin","full_name":"Merrin, Jack","first_name":"Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5145-4609"},{"full_name":"Heisenberg, Carl-Philipp J","last_name":"Heisenberg","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","first_name":"Carl-Philipp J"}],"corr_author":"1","oa":1,"doi":"10.1073/pnas.2122030119","year":"2022","title":"Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells","acknowledged_ssus":[{"_id":"Bio"},{"_id":"EM-Fac"},{"_id":"PreCl"}],"date_updated":"2026-07-06T12:45:39Z","quality_controlled":"1","status":"public","has_accepted_license":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","_id":"10766","isi":1,"date_created":"2022-02-20T23:01:31Z","article_number":"e2122030119","external_id":{"pmid":["35165179"],"isi":["000766926900009"]},"department":[{"_id":"CaHe"},{"_id":"EM-Fac"},{"_id":"Bio"}],"article_processing_charge":"No","month":"02","publication_status":"published","fulldoi":"https://doi.org/10.1073/pnas.2122030119","date_published":"2022-02-14T00:00:00Z","type":"journal_article","related_material":{"record":[{"relation":"earlier_version","id":"9750","status":"public"}]},"pmid":1,"publication":"Proceedings of the National Academy of Sciences of the United States of America","ddc":["570"],"ec_funded":1,"volume":119,"abstract":[{"text":"Tension of the actomyosin cell cortex plays a key role in determining cell–cell contact growth and size. The level of cortical tension outside of the cell–cell contact, when pulling at the contact edge, scales with the total size to which a cell–cell contact can grow [J.-L. Maître et al., Science 338, 253–256 (2012)]. Here, we show in zebrafish primary germ-layer progenitor cells that this monotonic relationship only applies to a narrow range of cortical tension increase and that above a critical threshold, contact size inversely scales with cortical tension. This switch from cortical tension increasing to decreasing progenitor cell–cell contact size is caused by cortical tension promoting E-cadherin anchoring to the actomyosin cytoskeleton, thereby increasing clustering and stability of E-cadherin at the contact. After tension-mediated E-cadherin stabilization at the contact exceeds a critical threshold level, the rate by which the contact expands in response to pulling forces from the cortex sharply drops, leading to smaller contacts at physiologically relevant timescales of contact formation. Thus, the activity of cortical tension in expanding cell–cell contact size is limited by tension-stabilizing E-cadherin–actin complexes at the contact.","lang":"eng"}],"day":"14","article_type":"original","scopus_import":"1","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734","call_identifier":"FP7"},{"_id":"260F1432-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"742573","name":"Interaction and feedback between cell mechanics and fate specification in vertebrate gastrulation"},{"name":"Modulation of adhesion function in cell-cell contact formation by cortical tension","grant_number":"187-2013","_id":"2521E28E-B435-11E9-9278-68D0E5697425"}],"citation":{"mla":"Slovakova, Jana, et al. “Tension-Dependent Stabilization of E-Cadherin Limits Cell-Cell Contact Expansion in Zebrafish Germ-Layer Progenitor Cells.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 8, e2122030119, National Academy of Sciences, 2022, doi:<a href=\"https://doi.org/10.1073/pnas.2122030119\">10.1073/pnas.2122030119</a>.","ista":"Slovakova J, Sikora MK, Arslan FN, Caballero Mancebo S, Krens G, Kaufmann W, Merrin J, Heisenberg C-PJ. 2022. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 119(8), e2122030119.","ama":"Slovakova J, Sikora MK, Arslan FN, et al. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2022;119(8). doi:<a href=\"https://doi.org/10.1073/pnas.2122030119\">10.1073/pnas.2122030119</a>","ieee":"J. Slovakova <i>et al.</i>, “Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 8. National Academy of Sciences, 2022.","chicago":"Slovakova, Jana, Mateusz K Sikora, Feyza N Arslan, Silvia Caballero Mancebo, Gabriel Krens, Walter Kaufmann, Jack Merrin, and Carl-Philipp J Heisenberg. “Tension-Dependent Stabilization of E-Cadherin Limits Cell-Cell Contact Expansion in Zebrafish Germ-Layer Progenitor Cells.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences, 2022. <a href=\"https://doi.org/10.1073/pnas.2122030119\">https://doi.org/10.1073/pnas.2122030119</a>.","short":"J. Slovakova, M.K. Sikora, F.N. Arslan, S. Caballero Mancebo, G. Krens, W. Kaufmann, J. Merrin, C.-P.J. Heisenberg, Proceedings of the National Academy of Sciences of the United States of America 119 (2022).","apa":"Slovakova, J., Sikora, M. K., Arslan, F. N., Caballero Mancebo, S., Krens, G., Kaufmann, W., … Heisenberg, C.-P. J. (2022). Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2122030119\">https://doi.org/10.1073/pnas.2122030119</a>"},"publication_identifier":{"eissn":["1091-6490"]},"file":[{"access_level":"open_access","success":1,"date_updated":"2022-02-21T08:45:11Z","file_size":1609678,"file_id":"10780","relation":"main_file","creator":"dernst","file_name":"2022_PNAS_Slovakova.pdf","checksum":"d49f83c3580613966f71768ddb9a55a5","date_created":"2022-02-21T08:45:11Z","content_type":"application/pdf"}],"file_date_updated":"2022-02-21T08:45:11Z","language":[{"iso":"eng"}],"issue":"8","acknowledgement":"We thank Guillaume Salbreaux, Silvia Grigolon, Edouard Hannezo, and Vanessa Barone for discussions and comments on the manuscript and Shayan Shamipour and Daniel Capek for help with data analysis. We also thank the Imaging & Optics, Electron Microscopy, and Zebrafish Facility Scientific Service Units at the Institute of Science and Technology Austria (ISTA)Nasser Darwish-Miranda  for continuous support. We acknowledge Hitoshi Morita for the gift of VinculinB-GFP plasmid. This research was supported by an ISTA Fellow Marie-Curie Co-funding of regional, national, and international programmes Grant P_IST_EU01 (to J.S.), European Molecular Biology Organization Long-Term Fellowship Grant, ALTF reference number: 187-2013 (to M.S.), Schroedinger Fellowship J4332-B28 (to M.S.), and European Research Council Advanced Grant (MECSPEC; to C.-P.H.).","tmp":{"image":"/images/cc_by_nc_nd.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"oa_version":"Published Version"},{"project":[{"call_identifier":"H2020","grant_number":"724373","name":"Cellular Navigation Along Spatial Gradients","_id":"25FE9508-B435-11E9-9278-68D0E5697425"},{"_id":"26018E70-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"P29911","name":"Mechanical adaptation of lamellipodial actin"}],"abstract":[{"lang":"eng","text":"A key attribute of persistent or recurring bacterial infections is the ability of the pathogen to evade the host’s immune response. Many Enterobacteriaceae express type 1 pili, a pre-adapted virulence trait, to invade host epithelial cells and establish persistent infections. However, the molecular mechanisms and strategies by which bacteria actively circumvent the immune response of the host remain poorly understood. Here, we identified CD14, the major co-receptor for lipopolysaccharide detection, on mouse dendritic cells (DCs) as a binding partner of FimH, the protein located at the tip of the type 1 pilus of Escherichia coli. The FimH amino acids involved in CD14 binding are highly conserved across pathogenic and non-pathogenic strains. Binding of the pathogenic strain CFT073 to CD14 reduced DC migration by overactivation of integrins and blunted expression of co-stimulatory molecules by overactivating the NFAT (nuclear factor of activated T-cells) pathway, both rate-limiting factors of T cell activation. This response was binary at the single-cell level, but averaged in larger populations exposed to both piliated and non-piliated pathogens, presumably via the exchange of immunomodulatory cytokines. While defining an active molecular mechanism of immune evasion by pathogens, the interaction between FimH and CD14 represents a potential target to interfere with persistent and recurrent infections, such as urinary tract infections or Crohn’s disease."}],"volume":11,"scopus_import":"1","day":"26","article_type":"original","ec_funded":1,"ddc":["570"],"publication":"eLife","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"acknowledgement":"We thank Ulrich Dobrindt for providing UPEC strains CFT073, UTI89, and 536, Frank Assen, Vlad Gavra, Maximilian Götz, Bor Kavčič, Jonna Alanko, and Eva Kiermaier for help with experiments and Robert Hauschild, Julian Stopp, and Saren Tasciyan for help with data analysis. We thank the IST Austria Scientific Service Units, especially the Bioimaging facility, the Preclinical facility and the Electron microscopy facility for technical support, Jakob Wallner and all members of the Guet and Sixt lab for fruitful discussions and Daria Siekhaus for critically reading the manuscript. This work was supported by grants from the Austrian Research Promotion Agency (FEMtech 868984) to IG, the European Research Council (CoG 724373), and the Austrian Science Fund (FWF P29911) to MS.","file":[{"creator":"cchlebak","relation":"main_file","file_id":"11861","file_size":2057577,"date_updated":"2022-08-16T08:57:37Z","success":1,"access_level":"open_access","content_type":"application/pdf","date_created":"2022-08-16T08:57:37Z","checksum":"002a3c7c7ea5caa9af9cfbea308f6ea4","file_name":"2022_eLife_Tomasek.pdf"}],"file_date_updated":"2022-08-16T08:57:37Z","citation":{"ama":"Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. <i>eLife</i>. 2022;11. doi:<a href=\"https://doi.org/10.7554/eLife.78995\">10.7554/eLife.78995</a>","mla":"Tomasek, Kathrin, et al. “Type 1 Piliated Uropathogenic Escherichia Coli Hijack the Host Immune Response by Binding to CD14.” <i>ELife</i>, vol. 11, e78995, eLife Sciences Publications, 2022, doi:<a href=\"https://doi.org/10.7554/eLife.78995\">10.7554/eLife.78995</a>.","ista":"Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. 2022. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. eLife. 11, e78995.","short":"K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022).","apa":"Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., &#38; Sixt, M. K. (2022). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.78995\">https://doi.org/10.7554/eLife.78995</a>","ieee":"K. Tomasek, A. F. Leithner, I. Glatzová, M. S. Lukesch, C. C. Guet, and M. K. Sixt, “Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14,” <i>eLife</i>, vol. 11. eLife Sciences Publications, 2022.","chicago":"Tomasek, Kathrin, Alexander F Leithner, Ivana Glatzová, Michael S. Lukesch, Calin C Guet, and Michael K Sixt. “Type 1 Piliated Uropathogenic Escherichia Coli Hijack the Host Immune Response by Binding to CD14.” <i>ELife</i>. eLife Sciences Publications, 2022. <a href=\"https://doi.org/10.7554/eLife.78995\">https://doi.org/10.7554/eLife.78995</a>."},"publication_identifier":{"eissn":["2050-084X"]},"_id":"11843","isi":1,"year":"2022","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"EM-Fac"}],"title":"Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14","date_updated":"2026-07-06T12:48:19Z","doi":"10.7554/eLife.78995","status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","intvolume":"        11","publisher":"eLife Sciences Publications","author":[{"last_name":"Tomasek","full_name":"Tomasek, Kathrin","first_name":"Kathrin","id":"3AEC8556-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3768-877X"},{"last_name":"Leithner","full_name":"Leithner, Alexander F","first_name":"Alexander F","id":"3B1B77E4-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1073-744X"},{"full_name":"Glatzová, Ivana","last_name":"Glatzová","id":"727b3c7d-4939-11ec-89b3-b9b0750ab74d","first_name":"Ivana"},{"last_name":"Lukesch","full_name":"Lukesch, Michael S.","first_name":"Michael S."},{"full_name":"Guet, Calin C","last_name":"Guet","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","first_name":"Calin C"},{"last_name":"Sixt","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","first_name":"Michael K","orcid":"0000-0002-6620-9179"}],"corr_author":"1","oa":1,"type":"journal_article","date_published":"2022-07-26T00:00:00Z","pmid":1,"related_material":{"record":[{"id":"10316","relation":"earlier_version","status":"public"}]},"fulldoi":"https://doi.org/10.7554/eLife.78995","article_processing_charge":"Yes","month":"07","department":[{"_id":"MiSi"},{"_id":"CaGu"}],"publication_status":"published","date_created":"2022-08-14T22:01:46Z","external_id":{"isi":["000838410200001"],"pmid":["35881547"]},"article_number":"e78995"},{"citation":{"ieee":"F. Lombardi <i>et al.</i>, “Alpha rhythm induces attenuation-amplification dynamics in neural activity cascades,” <i>bioRxiv</i>. .","chicago":"Lombardi, Fabrizio, Hans J. Herrmann, Liborio Parrino, Dietmar Plenz, Silvia Scarpetta, Anna Elisabetta Vaudano, Lucilla de Arcangelis, and Oren Shriki. “Alpha Rhythm Induces Attenuation-Amplification Dynamics in Neural Activity Cascades.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2022.03.03.482657\">https://doi.org/10.1101/2022.03.03.482657</a>.","apa":"Lombardi, F., Herrmann, H. J., Parrino, L., Plenz, D., Scarpetta, S., Vaudano, A. E., … Shriki, O. (n.d.). Alpha rhythm induces attenuation-amplification dynamics in neural activity cascades. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2022.03.03.482657\">https://doi.org/10.1101/2022.03.03.482657</a>","short":"F. Lombardi, H.J. Herrmann, L. Parrino, D. Plenz, S. Scarpetta, A.E. Vaudano, L. de Arcangelis, O. Shriki, BioRxiv (n.d.).","ista":"Lombardi F, Herrmann HJ, Parrino L, Plenz D, Scarpetta S, Vaudano AE, de Arcangelis L, Shriki O. Alpha rhythm induces attenuation-amplification dynamics in neural activity cascades. bioRxiv, <a href=\"https://doi.org/10.1101/2022.03.03.482657\">10.1101/2022.03.03.482657</a>.","mla":"Lombardi, Fabrizio, et al. “Alpha Rhythm Induces Attenuation-Amplification Dynamics in Neural Activity Cascades.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2022.03.03.482657\">10.1101/2022.03.03.482657</a>.","ama":"Lombardi F, Herrmann HJ, Parrino L, et al. Alpha rhythm induces attenuation-amplification dynamics in neural activity cascades. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2022.03.03.482657\">10.1101/2022.03.03.482657</a>"},"acknowledgement":"FL acknowledges support from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 754411. LdA acknowledges the Italian MIUR project PRIN2017WZFTZP for financial support and the project E-PASSION of the program VALERE 2019 funded by the University of Campania, Italy “L. Vanvitelli”. OS acknowledges support from the Israel Science Foundation, Grant No. 504/17. Supported in part by DIRP ZIAMH02797 to DP.","language":[{"iso":"eng"}],"oa_version":"Preprint","page":"25","publication":"bioRxiv","ec_funded":1,"day":"04","abstract":[{"lang":"eng","text":"Rhythmical cortical activity has long been recognized as a pillar in the architecture of brain functions. Yet, the dynamic organization of its underlying neuronal population activity remains elusive. Here we uncover a unique organizational principle regulating collective neural dynamics associated with the alpha rhythm in the awake resting-state. We demonstrate that cascades of neural activity obey attenuation-amplification dynamics (AAD), with a transition from the attenuation regime—within alpha cycles—to the amplification regime—across a few alpha cycles—that correlates with the characteristic frequency of the alpha rhythm. We find that this short-term AAD is part of a large-scale, size-dependent temporal structure of neural cascades that obeys the Omori law: Following large cascades, smaller cascades occur at a rate that decays as a power-law of the time elapsed from such events—a long-term AAD regulating brain activity over the timescale of seconds. We show that such an organization corresponds to the \"waxing and waning\" of the alpha rhythm. Importantly, we observe that short- and long-term AAD are unique to the awake resting-state, being absent during NREM sleep. These results provide a quantitative, dynamical description of the so-far-qualitative notion of the \"waxing and waning\" phenomenon, and suggest the AAD as a key principle governing resting-state dynamics across timescales."}],"project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"date_created":"2022-03-04T22:20:59Z","publication_status":"draft","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2022.03.03.482657"}],"department":[{"_id":"GaTk"}],"month":"03","OA_place":"repository","article_processing_charge":"No","fulldoi":"https://doi.org/10.1101/2022.03.03.482657","das_tickbox":"1","related_material":{"record":[{"status":"public","relation":"later_version","id":"14402"}]},"date_published":"2022-03-04T00:00:00Z","type":"preprint","author":[{"last_name":"Lombardi","full_name":"Lombardi, Fabrizio","first_name":"Fabrizio","id":"A057D288-3E88-11E9-986D-0CF4E5697425","orcid":"0000-0003-2623-5249"},{"first_name":"Hans J.","last_name":"Herrmann","full_name":"Herrmann, Hans J."},{"last_name":"Parrino","full_name":"Parrino, Liborio","first_name":"Liborio"},{"first_name":"Dietmar","last_name":"Plenz","full_name":"Plenz, Dietmar"},{"first_name":"Silvia","full_name":"Scarpetta, Silvia","last_name":"Scarpetta"},{"first_name":"Anna Elisabetta","full_name":"Vaudano, Anna Elisabetta","last_name":"Vaudano"},{"last_name":"de Arcangelis","full_name":"de Arcangelis, Lucilla","first_name":"Lucilla"},{"first_name":"Oren","full_name":"Shriki, Oren","last_name":"Shriki"}],"corr_author":"1","oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","doi":"10.1101/2022.03.03.482657","date_updated":"2026-07-06T12:48:55Z","year":"2022","title":"Alpha rhythm induces attenuation-amplification dynamics in neural activity cascades","_id":"10821"},{"citation":{"mla":"Ibáñez, Maria, et al. “The Importance of Surface Adsorbates in Solution-Processed Thermoelectric Materials.” <i>Proceedings of the NanoGe Spring Meeting 2022</i>, 159, Fundació de la comunitat valenciana SCITO, 2022, doi:<a href=\"https://doi.org/10.29363/nanoge.nsm.2022.159\">10.29363/nanoge.nsm.2022.159</a>.","ista":"Ibáñez M, Liu Y, Calcabrini M. 2022. The importance of surface adsorbates in solution-processed thermoelectric materials. Proceedings of the nanoGe Spring Meeting 2022. SNI: Semiconductor Nanocrystals, 159.","ama":"Ibáñez M, Liu Y, Calcabrini M. The importance of surface adsorbates in solution-processed thermoelectric materials. In: <i>Proceedings of the NanoGe Spring Meeting 2022</i>. Fundació de la comunitat valenciana SCITO; 2022. doi:<a href=\"https://doi.org/10.29363/nanoge.nsm.2022.159\">10.29363/nanoge.nsm.2022.159</a>","chicago":"Ibáñez, Maria, Yu Liu, and Mariano Calcabrini. “The Importance of Surface Adsorbates in Solution-Processed Thermoelectric Materials.” In <i>Proceedings of the NanoGe Spring Meeting 2022</i>. Fundació de la comunitat valenciana SCITO, 2022. <a href=\"https://doi.org/10.29363/nanoge.nsm.2022.159\">https://doi.org/10.29363/nanoge.nsm.2022.159</a>.","ieee":"M. Ibáñez, Y. Liu, and M. Calcabrini, “The importance of surface adsorbates in solution-processed thermoelectric materials,” in <i>Proceedings of the nanoGe Spring Meeting 2022</i>, Spain/Virtual, 2022.","short":"M. Ibáñez, Y. Liu, M. Calcabrini, in:, Proceedings of the NanoGe Spring Meeting 2022, Fundació de la comunitat valenciana SCITO, 2022.","apa":"Ibáñez, M., Liu, Y., &#38; Calcabrini, M. (2022). The importance of surface adsorbates in solution-processed thermoelectric materials. In <i>Proceedings of the nanoGe Spring Meeting 2022</i>. Spain/Virtual: Fundació de la comunitat valenciana SCITO. <a href=\"https://doi.org/10.29363/nanoge.nsm.2022.159\">https://doi.org/10.29363/nanoge.nsm.2022.159</a>"},"oa_version":"Published Version","language":[{"iso":"eng"}],"acknowledgement":"Werner Siemens Foundation\r\nEuropean Union's Horizon 2020\r\nFWF “Lise Meitner Fellowship”","ddc":["530"],"publication":"Proceedings of the nanoGe Spring Meeting 2022","project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}],"day":"07","month":"02","article_processing_charge":"No","department":[{"_id":"MaIb"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.29363/nanoge.nsm.2022.159"}],"publication_status":"published","date_created":"2024-05-29T05:38:47Z","conference":{"start_date":"2022-03-07","location":"Spain/Virtual","name":"SNI: Semiconductor Nanocrystals","end_date":"2022-03-11"},"article_number":"159","date_published":"2022-02-07T00:00:00Z","type":"conference_abstract","related_material":{"record":[{"status":"public","id":"10123","relation":"earlier_version"}]},"fulldoi":"https://doi.org/10.29363/nanoge.nsm.2022.159","publisher":"Fundació de la comunitat valenciana SCITO","corr_author":"1","oa":1,"author":[{"full_name":"Ibáñez, Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu","full_name":"Liu, Yu","last_name":"Liu"},{"id":"45D7531A-F248-11E8-B48F-1D18A9856A87","first_name":"Mariano","orcid":"0000-0003-4566-5877","last_name":"Calcabrini","full_name":"Calcabrini, Mariano"}],"_id":"17062","title":"The importance of surface adsorbates in solution-processed thermoelectric materials","year":"2022","date_updated":"2026-07-06T13:07:39Z","doi":"10.29363/nanoge.nsm.2022.159","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1"},{"article_processing_charge":"No","month":"07","department":[{"_id":"VlKo"}],"publication_status":"published","date_created":"2021-06-06T22:01:30Z","external_id":{"isi":["000650507600001"]},"date_published":"2022-07-01T00:00:00Z","type":"journal_article","das_tickbox":"1","fulldoi":"https://doi.org/10.1080/10556788.2021.1924715","publisher":"Taylor & Francis","intvolume":"        37","author":[{"first_name":"Olaniyi S.","last_name":"Iyiola","full_name":"Iyiola, Olaniyi S."},{"last_name":"Enyi","full_name":"Enyi, Cyril D.","first_name":"Cyril D."},{"orcid":"0000-0001-9224-7139","first_name":"Yekini","id":"3FC7CB58-F248-11E8-B48F-1D18A9856A87","full_name":"Shehu, Yekini","last_name":"Shehu"}],"corr_author":"1","isi":1,"_id":"9469","date_updated":"2026-07-07T05:33:15Z","year":"2022","title":"Reflected three-operator splitting method for monotone inclusion problem","doi":"10.1080/10556788.2021.1924715","status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"mla":"Iyiola, Olaniyi S., et al. “Reflected Three-Operator Splitting Method for Monotone Inclusion Problem.” <i>Optimization Methods and Software</i>, vol. 37, no. 4, Taylor &#38; Francis, 2022, pp. 1527–65, doi:<a href=\"https://doi.org/10.1080/10556788.2021.1924715\">10.1080/10556788.2021.1924715</a>.","ista":"Iyiola OS, Enyi CD, Shehu Y. 2022. Reflected three-operator splitting method for monotone inclusion problem. Optimization Methods and Software. 37(4), 1527–1565.","ama":"Iyiola OS, Enyi CD, Shehu Y. Reflected three-operator splitting method for monotone inclusion problem. <i>Optimization Methods and Software</i>. 2022;37(4):1527-1565. doi:<a href=\"https://doi.org/10.1080/10556788.2021.1924715\">10.1080/10556788.2021.1924715</a>","chicago":"Iyiola, Olaniyi S., Cyril D. Enyi, and Yekini Shehu. “Reflected Three-Operator Splitting Method for Monotone Inclusion Problem.” <i>Optimization Methods and Software</i>. Taylor &#38; Francis, 2022. <a href=\"https://doi.org/10.1080/10556788.2021.1924715\">https://doi.org/10.1080/10556788.2021.1924715</a>.","ieee":"O. S. Iyiola, C. D. Enyi, and Y. Shehu, “Reflected three-operator splitting method for monotone inclusion problem,” <i>Optimization Methods and Software</i>, vol. 37, no. 4. Taylor &#38; Francis, pp. 1527–1565, 2022.","short":"O.S. Iyiola, C.D. Enyi, Y. Shehu, Optimization Methods and Software 37 (2022) 1527–1565.","apa":"Iyiola, O. S., Enyi, C. D., &#38; Shehu, Y. (2022). Reflected three-operator splitting method for monotone inclusion problem. <i>Optimization Methods and Software</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/10556788.2021.1924715\">https://doi.org/10.1080/10556788.2021.1924715</a>"},"publication_identifier":{"eissn":["1029-4937"],"issn":["1055-6788"]},"oa_version":"None","language":[{"iso":"eng"}],"acknowledgement":"The authors are grateful to the anonymous referees and the handling Editor for their insightful comments which have improved the earlier version of the manuscript greatly. The second author is grateful to the University of Hafr Al Batin. The last author has received funding from the European Research Council (ERC) under the European Union's Seventh Framework Program (FP7-2007-2013) (Grant agreement No. 616160).","issue":"4","ec_funded":1,"publication":"Optimization Methods and Software","page":"1527-1565","project":[{"call_identifier":"FP7","grant_number":"616160","name":"Discrete Optimization in Computer Vision: Theory and Practice","_id":"25FBA906-B435-11E9-9278-68D0E5697425"}],"abstract":[{"lang":"eng","text":"In this paper, we consider reflected three-operator splitting methods for monotone inclusion problems in real Hilbert spaces. To do this, we first obtain weak convergence analysis and nonasymptotic O(1/n) convergence rate of the reflected Krasnosel'skiĭ-Mann iteration for finding a fixed point of nonexpansive mapping in real Hilbert spaces under some seemingly easy to implement conditions on the iterative parameters. We then apply our results to three-operator splitting for the monotone inclusion problem and consequently obtain the corresponding convergence analysis. Furthermore, we derive reflected primal-dual algorithms for highly structured monotone inclusion problems. Some numerical implementations are drawn from splitting methods to support the theoretical analysis."}],"volume":37,"scopus_import":"1","article_type":"original","day":"01"},{"language":[{"iso":"eng"}],"issue":"13","acknowledgement":"The second author has received funding from the European Research Council (ERC) under the European Union's Seventh Framework Program (FP7-2007-2013) (Grant agreement No. 616160).","oa_version":"None","citation":{"apa":"Ogbuisi, F. U., Shehu, Y., &#38; Yao, J. C. (2022). Convergence analysis of new inertial method for the split common null point problem. <i>Optimization</i>. Taylor &#38; Francis. <a href=\"https://doi.org/10.1080/02331934.2021.1914035\">https://doi.org/10.1080/02331934.2021.1914035</a>","short":"F.U. Ogbuisi, Y. Shehu, J.C. Yao, Optimization 71 (2022) 3767–3795.","ieee":"F. U. Ogbuisi, Y. Shehu, and J. C. Yao, “Convergence analysis of new inertial method for the split common null point problem,” <i>Optimization</i>, vol. 71, no. 13. Taylor &#38; Francis, pp. 3767–3795, 2022.","chicago":"Ogbuisi, Ferdinard U., Yekini Shehu, and Jen Chih Yao. “Convergence Analysis of New Inertial Method for the Split Common Null Point Problem.” <i>Optimization</i>. Taylor &#38; Francis, 2022. <a href=\"https://doi.org/10.1080/02331934.2021.1914035\">https://doi.org/10.1080/02331934.2021.1914035</a>.","ama":"Ogbuisi FU, Shehu Y, Yao JC. Convergence analysis of new inertial method for the split common null point problem. <i>Optimization</i>. 2022;71(13):3767-3795. doi:<a href=\"https://doi.org/10.1080/02331934.2021.1914035\">10.1080/02331934.2021.1914035</a>","ista":"Ogbuisi FU, Shehu Y, Yao JC. 2022. Convergence analysis of new inertial method for the split common null point problem. Optimization. 71(13), 3767–3795.","mla":"Ogbuisi, Ferdinard U., et al. “Convergence Analysis of New Inertial Method for the Split Common Null Point Problem.” <i>Optimization</i>, vol. 71, no. 13, Taylor &#38; Francis, 2022, pp. 3767–95, doi:<a href=\"https://doi.org/10.1080/02331934.2021.1914035\">10.1080/02331934.2021.1914035</a>."},"publication_identifier":{"issn":["0233-1934"],"eissn":["1029-4945"]},"volume":71,"abstract":[{"text":"In this paper, we propose a new iterative method with alternated inertial step for solving split common null point problem in real Hilbert spaces. We obtain weak convergence of the proposed iterative algorithm. Furthermore, we introduce the notion of bounded linear regularity property for the split common null point problem and obtain the linear convergence property for the new algorithm under some mild assumptions. Finally, we provide some numerical examples to demonstrate the performance and efficiency of the proposed method.","lang":"eng"}],"article_type":"original","day":"01","scopus_import":"1","project":[{"call_identifier":"FP7","name":"Discrete Optimization in Computer Vision: Theory and Practice","grant_number":"616160","_id":"25FBA906-B435-11E9-9278-68D0E5697425"}],"publication":"Optimization","page":"3767-3795","ec_funded":1,"das_tickbox":"1","fulldoi":"https://doi.org/10.1080/02331934.2021.1914035","date_published":"2022-11-01T00:00:00Z","type":"journal_article","date_created":"2021-05-02T22:01:29Z","external_id":{"isi":["000640109300001"]},"department":[{"_id":"VlKo"}],"article_processing_charge":"No","month":"11","publication_status":"published","doi":"10.1080/02331934.2021.1914035","date_updated":"2026-07-07T05:32:47Z","title":"Convergence analysis of new inertial method for the split common null point problem","year":"2022","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","quality_controlled":"1","isi":1,"_id":"9365","publisher":"Taylor & Francis","intvolume":"        71","author":[{"first_name":"Ferdinard U.","last_name":"Ogbuisi","full_name":"Ogbuisi, Ferdinard U."},{"last_name":"Shehu","full_name":"Shehu, Yekini","id":"3FC7CB58-F248-11E8-B48F-1D18A9856A87","first_name":"Yekini","orcid":"0000-0001-9224-7139"},{"first_name":"Jen Chih","last_name":"Yao","full_name":"Yao, Jen Chih"}]},{"citation":{"apa":"Barbier, J., Hou, T., Mondelli, M., &#38; Saenz, M. (2022). The price of ignorance: How much does it cost to forget noise structure in low-rank matrix estimation? In <i>36th Conference on Neural Information Processing Systems</i> (Vol. 35). New Orleans, LA, United States: Neural Information Processing Systems Foundation.","short":"J. Barbier, T. Hou, M. Mondelli, M. Saenz, in:, 36th Conference on Neural Information Processing Systems, Neural Information Processing Systems Foundation, 2022.","ieee":"J. Barbier, T. Hou, M. Mondelli, and M. Saenz, “The price of ignorance: How much does it cost to forget noise structure in low-rank matrix estimation?,” in <i>36th Conference on Neural Information Processing Systems</i>, New Orleans, LA, United States, 2022, vol. 35.","chicago":"Barbier, Jean, TianQi Hou, Marco Mondelli, and Manuel Saenz. “The Price of Ignorance: How Much Does It Cost to Forget Noise Structure in Low-Rank Matrix Estimation?” In <i>36th Conference on Neural Information Processing Systems</i>, Vol. 35. Neural Information Processing Systems Foundation, 2022.","ama":"Barbier J, Hou T, Mondelli M, Saenz M. The price of ignorance: How much does it cost to forget noise structure in low-rank matrix estimation? In: <i>36th Conference on Neural Information Processing Systems</i>. Vol 35. Neural Information Processing Systems Foundation; 2022.","ista":"Barbier J, Hou T, Mondelli M, Saenz M. 2022. The price of ignorance: How much does it cost to forget noise structure in low-rank matrix estimation? 36th Conference on Neural Information Processing Systems. NeurIPS: Neural Information Processing Systems, Advances in Neural Information Processing Systems, vol. 35.","mla":"Barbier, Jean, et al. “The Price of Ignorance: How Much Does It Cost to Forget Noise Structure in Low-Rank Matrix Estimation?” <i>36th Conference on Neural Information Processing Systems</i>, vol. 35, Neural Information Processing Systems Foundation, 2022."},"publication_identifier":{"issn":["1049-5258"],"isbn":["9781713871088"]},"oa_version":"Preprint","language":[{"iso":"eng"}],"acknowledgement":"M. Mondelli was partially supported by the 2019 Lopez-Loreta Prize. The authors acknowledge\r\ndiscussions with A. Krajenbrink, M. Robinson, A. Depope, N. Macris and F. Pourkamali.\r\n","publication":"36th Conference on Neural Information Processing Systems","abstract":[{"text":"We consider the problem of estimating a rank-1 signal corrupted by structured rotationally invariant noise, and address the following question: how well do inference algorithms perform when the noise statistics is unknown and hence Gaussian noise is assumed? While the matched Bayes-optimal setting with unstructured noise is well understood, the analysis of this mismatched problem is only at its premises. In this paper, we make a step towards understanding the effect of the strong source of mismatch which is the noise statistics. Our main technical contribution is the rigorous analysis of a Bayes estimator and of an approximate message passing (AMP) algorithm, both of which incorrectly assume a Gaussian setup. The first result exploits the theory of spherical integrals and of low-rank matrix perturbations; the idea behind the second one is to design and analyze an artificial AMP which, by taking advantage of the flexibility in the denoisers, is able to \"correct\" the mismatch. Armed with these sharp asymptotic characterizations, we unveil a rich and often unexpected phenomenology. For example, despite AMP is in principle designed to efficiently compute the Bayes estimator, the former is outperformed by the latter in terms of mean-square error. We show that this performance gap is due to an incorrect estimation of the signal norm. In fact, when the SNR is large enough, the overlaps of the AMP and the Bayes estimator coincide, and they even match those of optimal estimators taking into account the structure of the noise.","lang":"eng"}],"alternative_title":["Advances in Neural Information Processing Systems"],"volume":35,"scopus_import":"1","day":"20","month":"11","article_processing_charge":"No","department":[{"_id":"MaMo"}],"publication_status":"published","main_file_link":[{"url":"https://arxiv.org/abs/2205.10009","open_access":"1"}],"date_created":"2023-02-10T13:45:41Z","external_id":{"arxiv":["2205.10009"]},"conference":{"name":"NeurIPS: Neural Information Processing Systems","end_date":"2022-12-09","start_date":"2022-11-28","location":"New Orleans, LA, United States"},"type":"conference","date_published":"2022-11-20T00:00:00Z","arxiv":1,"das_tickbox":"1","intvolume":"        35","publisher":"Neural Information Processing Systems Foundation","oa":1,"author":[{"full_name":"Barbier, Jean","last_name":"Barbier","first_name":"Jean"},{"first_name":"TianQi","last_name":"Hou","full_name":"Hou, TianQi"},{"orcid":"0000-0002-3242-7020","first_name":"Marco","id":"27EB676C-8706-11E9-9510-7717E6697425","full_name":"Mondelli, Marco","last_name":"Mondelli"},{"first_name":"Manuel","full_name":"Saenz, Manuel","last_name":"Saenz"}],"corr_author":"1","_id":"12536","year":"2022","title":"The price of ignorance: How much does it cost to forget noise structure in low-rank matrix estimation?","date_updated":"2026-07-07T06:38:45Z","status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"type":"conference","date_published":"2022-09-15T00:00:00Z","arxiv":1,"das_tickbox":"1","fulldoi":"https://doi.org/10.4230/LIPIcs.CONCUR.2022.11","month":"09","article_processing_charge":"No","department":[{"_id":"KrCh"}],"publication_status":"published","date_created":"2023-03-28T08:09:32Z","external_id":{"arxiv":["2008.04824"]},"conference":{"start_date":"2022-09-13","location":"Warsaw, Poland","end_date":"2022-09-16","name":"CONCUR: Conference on Concurrency Theory"},"article_number":"11","_id":"12775","year":"2022","title":"Anytime guarantees for reachability in uncountable Markov decision processes","date_updated":"2026-07-07T13:37:58Z","doi":"10.4230/LIPIcs.CONCUR.2022.11","status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","intvolume":"       243","oa":1,"author":[{"full_name":"Grover, Kush","last_name":"Grover","first_name":"Kush"},{"orcid":"0000-0002-8122-2881","id":"44CEF464-F248-11E8-B48F-1D18A9856A87","first_name":"Jan","full_name":"Kretinsky, Jan","last_name":"Kretinsky"},{"full_name":"Meggendorfer, Tobias","last_name":"Meggendorfer","orcid":"0000-0002-1712-2165","first_name":"Tobias","id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1"},{"first_name":"Maimilian","full_name":"Weininger, Maimilian","last_name":"Weininger"}],"corr_author":"1","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"acknowledgement":"Kush Grover: The author has been supported by the DFG research training group GRK\r\n2428 ConVeY.\r\nMaximilian Weininger: The author has been partially supported by DFG projects 383882557\r\nStatistical Unbounded Verification (SUV) and 427755713 Group-By Objectives in Probabilistic\r\nVerification (GOPro)","file":[{"content_type":"application/pdf","file_name":"2022_LIPIcS_Grover.pdf","checksum":"e282e43d3ae0ba6e067b72f4583e13c0","date_created":"2023-09-26T10:43:15Z","file_size":960036,"file_id":"14372","relation":"main_file","creator":"dernst","access_level":"open_access","success":1,"date_updated":"2023-09-26T10:43:15Z"}],"file_date_updated":"2023-09-26T10:43:15Z","citation":{"short":"K. Grover, J. Kretinsky, T. Meggendorfer, M. Weininger, in:, 33rd International Conference on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022.","apa":"Grover, K., Kretinsky, J., Meggendorfer, T., &#38; Weininger, M. (2022). Anytime guarantees for reachability in uncountable Markov decision processes. In <i>33rd International Conference on Concurrency Theory</i> (Vol. 243). Warsaw, Poland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2022.11\">https://doi.org/10.4230/LIPIcs.CONCUR.2022.11</a>","ieee":"K. Grover, J. Kretinsky, T. Meggendorfer, and M. Weininger, “Anytime guarantees for reachability in uncountable Markov decision processes,” in <i>33rd International Conference on Concurrency Theory</i>, Warsaw, Poland, 2022, vol. 243.","chicago":"Grover, Kush, Jan Kretinsky, Tobias Meggendorfer, and Maimilian Weininger. “Anytime Guarantees for Reachability in Uncountable Markov Decision Processes.” In <i>33rd International Conference on Concurrency Theory</i>, Vol. 243. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2022.11\">https://doi.org/10.4230/LIPIcs.CONCUR.2022.11</a>.","ama":"Grover K, Kretinsky J, Meggendorfer T, Weininger M. Anytime guarantees for reachability in uncountable Markov decision processes. In: <i>33rd International Conference on Concurrency Theory</i>. Vol 243. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2022. doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2022.11\">10.4230/LIPIcs.CONCUR.2022.11</a>","mla":"Grover, Kush, et al. “Anytime Guarantees for Reachability in Uncountable Markov Decision Processes.” <i>33rd International Conference on Concurrency Theory</i>, vol. 243, 11, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2022, doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2022.11\">10.4230/LIPIcs.CONCUR.2022.11</a>.","ista":"Grover K, Kretinsky J, Meggendorfer T, Weininger M. 2022. Anytime guarantees for reachability in uncountable Markov decision processes. 33rd International Conference on Concurrency Theory. CONCUR: Conference on Concurrency Theory, LIPIcs, vol. 243, 11."},"publication_identifier":{"issn":["1868-8969"]},"abstract":[{"lang":"eng","text":"We consider the problem of approximating the reachability probabilities in Markov decision processes (MDP) with uncountable (continuous) state and action spaces. While there are algorithms that, for special classes of such MDP, provide a sequence of approximations converging to the true value in the limit, our aim is to obtain an algorithm with guarantees on the precision of the approximation.\r\nAs this problem is undecidable in general, assumptions on the MDP are necessary. Our main contribution is to identify sufficient assumptions that are as weak as possible, thus approaching the \"boundary\" of which systems can be correctly and reliably analyzed. To this end, we also argue why each of our assumptions is necessary for algorithms based on processing finitely many observations.\r\nWe present two solution variants. The first one provides converging lower bounds under weaker assumptions than typical ones from previous works concerned with guarantees. The second one then utilizes stronger assumptions to additionally provide converging upper bounds. Altogether, we obtain an anytime algorithm, i.e. yielding a sequence of approximants with known and iteratively improving precision, converging to the true value in the limit. Besides, due to the generality of our assumptions, our algorithms are very general templates, readily allowing for various heuristics from literature in contrast to, e.g., a specific discretization algorithm. Our theoretical contribution thus paves the way for future practical improvements without sacrificing correctness guarantees."}],"alternative_title":["LIPIcs"],"volume":243,"scopus_import":"1","day":"15","publication":"33rd International Conference on Concurrency Theory","ddc":["000"]},{"_id":"12236","isi":1,"status":"public","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-07-07T14:04:14Z","year":"2022","title":"CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction","doi":"10.1021/acsami.2c11627","author":[{"first_name":"Xiang","full_name":"Wang, Xiang","last_name":"Wang"},{"last_name":"Zuo","full_name":"Zuo, Yong","first_name":"Yong"},{"id":"03a7e858-01b1-11ec-8b71-99ae6c4a05bc","first_name":"Sharona","full_name":"Horta, Sharona","last_name":"Horta"},{"first_name":"Ren","full_name":"He, Ren","last_name":"He"},{"last_name":"Yang","full_name":"Yang, Linlin","first_name":"Linlin"},{"last_name":"Ostovari Moghaddam","full_name":"Ostovari Moghaddam, Ahmad","first_name":"Ahmad"},{"last_name":"Ibáñez","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","orcid":"0000-0001-5013-2843"},{"first_name":"Xueqiang","full_name":"Qi, Xueqiang","last_name":"Qi"},{"first_name":"Andreu","full_name":"Cabot, Andreu","last_name":"Cabot"}],"publisher":"American Chemical Society","intvolume":"        14","pmid":1,"type":"journal_article","date_published":"2022-10-14T00:00:00Z","fulldoi":"https://doi.org/10.1021/acsami.2c11627","das_tickbox":"1","publication_status":"published","article_processing_charge":"No","month":"10","department":[{"_id":"MaIb"}],"external_id":{"isi":["000873782700001"],"pmid":["36239982"]},"date_created":"2023-01-16T09:51:10Z","scopus_import":"1","day":"14","article_type":"original","abstract":[{"text":"High-entropy materials offer numerous advantages as catalysts, including a flexible composition to tune the catalytic activity and selectivity and a large variety of adsorption/reaction sites for multistep or multiple reactions. Herein, we report on the synthesis, properties, and electrocatalytic performance of an amorphous high-entropy boride based on abundant transition metals, CoFeNiMnZnB. This metal boride provides excellent performance toward the oxygen evolution reaction (OER), including a low overpotential of 261 mV at 10 mA cm–2, a reduced Tafel slope of 56.8 mV dec–1, and very high stability. The outstanding OER performance of CoFeNiMnZnB is attributed to the synergistic interactions between the different metals, the leaching of Zn ions, the generation of oxygen vacancies, and the in situ formation of an amorphous oxyhydroxide at the CoFeNiMnZnB surface during the OER.","lang":"eng"}],"volume":14,"page":"48212-48219","publication":"ACS Applied Materials and Interfaces","oa_version":"None","acknowledgement":"This work was supported by the Spanish MCIN project COMBENERGY (PID2019-105490RB-C32). X.W. and L.Y. thank the China Scholarship Council (CSC) for the scholarship support.","issue":"42","language":[{"iso":"eng"}],"publication_identifier":{"issn":["1944-8244"],"eissn":["1944-8252"]},"citation":{"ama":"Wang X, Zuo Y, Horta S, et al. CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. <i>ACS Applied Materials and Interfaces</i>. 2022;14(42):48212-48219. doi:<a href=\"https://doi.org/10.1021/acsami.2c11627\">10.1021/acsami.2c11627</a>","ista":"Wang X, Zuo Y, Horta S, He R, Yang L, Ostovari Moghaddam A, Ibáñez M, Qi X, Cabot A. 2022. CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. ACS Applied Materials and Interfaces. 14(42), 48212–48219.","mla":"Wang, Xiang, et al. “CoFeNiMnZnB as a High-Entropy Metal Boride to Boost the Oxygen Evolution Reaction.” <i>ACS Applied Materials and Interfaces</i>, vol. 14, no. 42, American Chemical Society, 2022, pp. 48212–19, doi:<a href=\"https://doi.org/10.1021/acsami.2c11627\">10.1021/acsami.2c11627</a>.","apa":"Wang, X., Zuo, Y., Horta, S., He, R., Yang, L., Ostovari Moghaddam, A., … Cabot, A. (2022). CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction. <i>ACS Applied Materials and Interfaces</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsami.2c11627\">https://doi.org/10.1021/acsami.2c11627</a>","short":"X. Wang, Y. Zuo, S. Horta, R. He, L. Yang, A. Ostovari Moghaddam, M. Ibáñez, X. Qi, A. Cabot, ACS Applied Materials and Interfaces 14 (2022) 48212–48219.","chicago":"Wang, Xiang, Yong Zuo, Sharona Horta, Ren He, Linlin Yang, Ahmad Ostovari Moghaddam, Maria Ibáñez, Xueqiang Qi, and Andreu Cabot. “CoFeNiMnZnB as a High-Entropy Metal Boride to Boost the Oxygen Evolution Reaction.” <i>ACS Applied Materials and Interfaces</i>. American Chemical Society, 2022. <a href=\"https://doi.org/10.1021/acsami.2c11627\">https://doi.org/10.1021/acsami.2c11627</a>.","ieee":"X. Wang <i>et al.</i>, “CoFeNiMnZnB as a high-entropy metal boride to boost the oxygen evolution reaction,” <i>ACS Applied Materials and Interfaces</i>, vol. 14, no. 42. American Chemical Society, pp. 48212–48219, 2022."},"keyword":["General Materials Science"]},{"publication_status":"published","department":[{"_id":"MaRo"}],"article_processing_charge":"Yes","month":"04","article_number":"e12280","external_id":{"pmid":["35475137"]},"date_created":"2024-05-29T06:13:25Z","pmid":1,"date_published":"2022-04-20T00:00:00Z","type":"journal_article","fulldoi":"https://doi.org/10.1002/dad2.12280","das_tickbox":"1","oa":1,"author":[{"first_name":"Robert F.","full_name":"Hillary, Robert F.","last_name":"Hillary"},{"full_name":"Gadd, Danni A.","last_name":"Gadd","first_name":"Danni A."},{"last_name":"McCartney","full_name":"McCartney, Daniel L.","first_name":"Daniel L."},{"full_name":"Shi, Liu","last_name":"Shi","first_name":"Liu"},{"first_name":"Archie","last_name":"Campbell","full_name":"Campbell, Archie"},{"last_name":"Walker","full_name":"Walker, Rosie M.","first_name":"Rosie M."},{"last_name":"Ritchie","full_name":"Ritchie, Craig W.","first_name":"Craig W."},{"full_name":"Deary, Ian J.","last_name":"Deary","first_name":"Ian J."},{"last_name":"Evans","full_name":"Evans, Kathryn L.","first_name":"Kathryn L."},{"first_name":"Alejo J.","full_name":"Nevado‐Holgado, Alejo J.","last_name":"Nevado‐Holgado"},{"full_name":"Hayward, Caroline","last_name":"Hayward","first_name":"Caroline"},{"full_name":"Porteous, David J.","last_name":"Porteous","first_name":"David J."},{"first_name":"Andrew M.","full_name":"McIntosh, Andrew M.","last_name":"McIntosh"},{"first_name":"Simon","last_name":"Lovestone","full_name":"Lovestone, Simon"},{"full_name":"Robinson, Matthew Richard","last_name":"Robinson","orcid":"0000-0001-8982-8813","first_name":"Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425"},{"first_name":"Riccardo E.","last_name":"Marioni","full_name":"Marioni, Riccardo E."}],"intvolume":"        14","publisher":"Wiley","_id":"17076","status":"public","quality_controlled":"1","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1002/dad2.12280","date_updated":"2026-07-08T05:51:18Z","title":"Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk","year":"2022","file_date_updated":"2024-07-31T11:27:29Z","file":[{"checksum":"49c8597b588ef1c63897703a32b7967b","file_name":"2023_AlzheimersDementia_Hillary.pdf","date_created":"2024-07-31T11:27:29Z","content_type":"application/pdf","success":1,"access_level":"open_access","date_updated":"2024-07-31T11:27:29Z","relation":"main_file","file_id":"17356","file_size":975181,"creator":"dernst"}],"publication_identifier":{"eissn":["2352-8729"]},"citation":{"chicago":"Hillary, Robert F., Danni A. Gadd, Daniel L. McCartney, Liu Shi, Archie Campbell, Rosie M. Walker, Craig W. Ritchie, et al. “Genome‐ and Epigenome‐wide Studies of Plasma Protein Biomarkers for Alzheimer’s Disease Implicate TBCA and TREM2 in Disease Risk.” <i>Alzheimer’s &#38; Dementia</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/dad2.12280\">https://doi.org/10.1002/dad2.12280</a>.","ieee":"R. F. Hillary <i>et al.</i>, “Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer’s disease implicate TBCA and TREM2 in disease risk,” <i>Alzheimer’s &#38; Dementia</i>, vol. 14, no. 1. Wiley, 2022.","apa":"Hillary, R. F., Gadd, D. A., McCartney, D. L., Shi, L., Campbell, A., Walker, R. M., … Marioni, R. E. (2022). Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer’s disease implicate TBCA and TREM2 in disease risk. <i>Alzheimer’s &#38; Dementia</i>. Wiley. <a href=\"https://doi.org/10.1002/dad2.12280\">https://doi.org/10.1002/dad2.12280</a>","short":"R.F. Hillary, D.A. Gadd, D.L. McCartney, L. Shi, A. Campbell, R.M. Walker, C.W. Ritchie, I.J. Deary, K.L. Evans, A.J. Nevado‐Holgado, C. Hayward, D.J. Porteous, A.M. McIntosh, S. Lovestone, M.R. Robinson, R.E. Marioni, Alzheimer’s &#38; Dementia 14 (2022).","ista":"Hillary RF, Gadd DA, McCartney DL, Shi L, Campbell A, Walker RM, Ritchie CW, Deary IJ, Evans KL, Nevado‐Holgado AJ, Hayward C, Porteous DJ, McIntosh AM, Lovestone S, Robinson MR, Marioni RE. 2022. Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer’s disease implicate TBCA and TREM2 in disease risk. Alzheimer’s &#38; Dementia. 14(1), e12280.","mla":"Hillary, Robert F., et al. “Genome‐ and Epigenome‐wide Studies of Plasma Protein Biomarkers for Alzheimer’s Disease Implicate TBCA and TREM2 in Disease Risk.” <i>Alzheimer’s &#38; Dementia</i>, vol. 14, no. 1, e12280, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/dad2.12280\">10.1002/dad2.12280</a>.","ama":"Hillary RF, Gadd DA, McCartney DL, et al. Genome‐ and epigenome‐wide studies of plasma protein biomarkers for Alzheimer’s disease implicate TBCA and TREM2 in disease risk. <i>Alzheimer’s &#38; Dementia</i>. 2022;14(1). doi:<a href=\"https://doi.org/10.1002/dad2.12280\">10.1002/dad2.12280</a>"},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","issue":"1","acknowledgement":"This research was funded in whole, or in part, by Wellcome [108890/Z/15/Z, 104036/Z/14/Z]. For the purpose of open access, the author has applied a CC BY public copyright license to any Author Accepted Manuscript version arising from this submission. The authors are grateful to the families who took part in this study, the general practitioners, and the Scottish School of Primary Care for their help in recruiting them and the wider Generation Scotland team. Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006]. Genotyping and DNA methylation profiling of the Generation Scotland samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland, and was funded by the Medical Research Council (MRC) UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” ([STRADL] Reference [104036/Z/14/Z]). Andrew M. McIntosh is supported by Wellcome [104036/Z/14/Z, 216767/Z/19/Z, 220857/Z/20/Z], United Kingdom Research and Innovation (UKRI) MRC [MC_PC_17209, MR/S035818/1] and the European Union H2020 [SEP-210574971]. Ian J. Deary received support from Age UK, Wellcome, and the Medical Research Council. David J. Porteous is supported by Wellcome as prinicpal investigator (PI), and MRC and National Institute for Health Research (NIHR) grants as co-PI, made to the University of Edinburgh. Robert F. Hillary and Danni A. Gadd are supported by funding from the Wellcome 4-year PhD in Translational Neuroscience—training the next generation of basic neuroscientists to embrace clinical research [108890/Z/15/Z]. Daniel L. McCartney and Riccardo E. Marioni are supported by Alzheimer's Research UK major project grant ARUK-PG2017B-10. Riccardo E. Marioni is supported by Alzheimer's Society major project grant AS-PG-19b-010. Proteomic analyses in STRADL were supported by Dementias Platform UK (DPUK). DPUK funded this work through core grant support from the Medical Research Council [MR/L023784/2]. Kathryn L. Evans was supported by a grant from Alzheimer's Research UK, paid to the University of Edinburgh. Alejo J. Nevado-Holgado was funded by a Horizon 2020 Virtual Brain Cloud project (H2020-SC1-DTH-2018-1), in addition to funding from the MRC, UK Rosetrees, and King Abdullah University of Science and Technology, Saudi Arabia. Caroline Hayward is supported by an MRC University Unit Programme Grant MC_UU_00007/10 (QTL in Health and Disease). Liu Shi is funded by DPUK through MRC [MR/L023784/2] and the UK Medical Research Council Award to the University of Oxford [MC_PC_17215]. Liu Shi received support from the NIHR Biomedical Research Centre at Oxford Health NHS Foundation Trust. Matthew R. Robinson is funded by a Swiss National Science Foundation Eccellenza Grant [PCEGP3-181181].","language":[{"iso":"eng"}],"ddc":["570"],"publication":"Alzheimer's & Dementia","article_type":"original","day":"20","scopus_import":"1","volume":14,"abstract":[{"text":"Introduction: The levels of many blood proteins are associated with Alzheimer's disease (AD) or its pathological hallmarks. Elucidating the molecular factors that control circulating levels of these proteins may help to identify proteins associated with disease risk mechanisms.\r\n\r\nMethods: Genome-wide and epigenome-wide studies (nindividuals ≤1064) were performed on plasma levels of 282 AD-associated proteins, identified by a structured literature review. Bayesian penalized regression estimated contributions of genetic and epigenetic variation toward inter-individual differences in plasma protein levels. Mendelian randomization (MR) and co-localization tested associations between proteins and disease-related phenotypes.\r\n\r\nResults: Sixty-four independent genetic and 26 epigenetic loci were associated with 45 proteins. Novel findings included an association between plasma triggering receptor expressed on myeloid cells 2 (TREM2) levels and a polymorphism and cytosine-phosphate-guanine (CpG) site within the MS4A4A locus. Higher plasma tubulin-specific chaperone A (TBCA) and TREM2 levels were significantly associated with lower AD risk.\r\n\r\nDiscussion: Our data inform the regulation of biomarker levels and their relationships with AD.","lang":"eng"}]},{"publication_status":"published","article_processing_charge":"Yes (via OA deal)","month":"08","department":[{"_id":"MaIb"},{"_id":"EM-Fac"}],"external_id":{"isi":["000828274200001"],"pmid":["38505739"]},"article_number":"e202207002","date_created":"2022-07-31T22:01:48Z","pmid":1,"type":"journal_article","date_published":"2022-08-26T00:00:00Z","fulldoi":"https://doi.org/10.1002/anie.202207002","das_tickbox":"1","corr_author":"1","author":[{"orcid":"0000-0002-9515-4277","first_name":"Cheng","id":"9E331C2E-9F27-11E9-AE48-5033E6697425","full_name":"Chang, Cheng","last_name":"Chang"},{"full_name":"Liu, Yu","last_name":"Liu","orcid":"0000-0001-7313-6740","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","first_name":"Yu"},{"full_name":"Lee, Seungho","last_name":"Lee","orcid":"0000-0002-6962-8598","id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho"},{"first_name":"Maria","full_name":"Spadaro, Maria","last_name":"Spadaro"},{"last_name":"Koskela","full_name":"Koskela, Kristopher M.","first_name":"Kristopher M."},{"full_name":"Kleinhanns, Tobias","last_name":"Kleinhanns","orcid":"0000-0003-1537-7436","first_name":"Tobias","id":"8BD9DE16-AB3C-11E9-9C8C-2A03E6697425"},{"full_name":"Costanzo, Tommaso","last_name":"Costanzo","orcid":"0000-0001-9732-3815","id":"D93824F4-D9BA-11E9-BB12-F207E6697425","first_name":"Tommaso"},{"first_name":"Jordi","last_name":"Arbiol","full_name":"Arbiol, Jordi"},{"first_name":"Richard L.","last_name":"Brutchey","full_name":"Brutchey, Richard L."},{"last_name":"Ibáñez","full_name":"Ibáñez, Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","orcid":"0000-0001-5013-2843"}],"oa":1,"publisher":"Wiley","intvolume":"        61","isi":1,"_id":"11705","quality_controlled":"1","has_accepted_license":"1","status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2026-07-08T05:53:49Z","title":"Surface functionalization of surfactant-free particles: A strategy to tailor the properties of nanocomposites for enhanced thermoelectric performance","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"NanoFab"}],"year":"2022","doi":"10.1002/anie.202207002","file_date_updated":"2023-02-02T08:01:00Z","file":[{"content_type":"application/pdf","checksum":"ad601f2b9e26e46ab4785162be58b5ed","file_name":"2022_AngewandteChemieInternat_Chang.pdf","date_created":"2023-02-02T08:01:00Z","file_id":"12476","relation":"main_file","file_size":4072650,"creator":"dernst","success":1,"access_level":"open_access","date_updated":"2023-02-02T08:01:00Z"}],"publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"citation":{"ama":"Chang C, Liu Y, Lee S, et al. Surface functionalization of surfactant-free particles: A strategy to tailor the properties of nanocomposites for enhanced thermoelectric performance. <i>Angewandte Chemie International Edition</i>. 2022;61(35). doi:<a href=\"https://doi.org/10.1002/anie.202207002\">10.1002/anie.202207002</a>","ista":"Chang C, Liu Y, Lee S, Spadaro M, Koskela KM, Kleinhanns T, Costanzo T, Arbiol J, Brutchey RL, Ibáñez M. 2022. Surface functionalization of surfactant-free particles: A strategy to tailor the properties of nanocomposites for enhanced thermoelectric performance. Angewandte Chemie International Edition. 61(35), e202207002.","mla":"Chang, Cheng, et al. “Surface Functionalization of Surfactant-Free Particles: A Strategy to Tailor the Properties of Nanocomposites for Enhanced Thermoelectric Performance.” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 35, e202207002, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/anie.202207002\">10.1002/anie.202207002</a>.","apa":"Chang, C., Liu, Y., Lee, S., Spadaro, M., Koskela, K. M., Kleinhanns, T., … Ibáñez, M. (2022). Surface functionalization of surfactant-free particles: A strategy to tailor the properties of nanocomposites for enhanced thermoelectric performance. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202207002\">https://doi.org/10.1002/anie.202207002</a>","short":"C. Chang, Y. Liu, S. Lee, M. Spadaro, K.M. Koskela, T. Kleinhanns, T. Costanzo, J. Arbiol, R.L. Brutchey, M. Ibáñez, Angewandte Chemie International Edition 61 (2022).","chicago":"Chang, Cheng, Yu Liu, Seungho Lee, Maria Spadaro, Kristopher M. Koskela, Tobias Kleinhanns, Tommaso Costanzo, Jordi Arbiol, Richard L. Brutchey, and Maria Ibáñez. “Surface Functionalization of Surfactant-Free Particles: A Strategy to Tailor the Properties of Nanocomposites for Enhanced Thermoelectric Performance.” <i>Angewandte Chemie International Edition</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/anie.202207002\">https://doi.org/10.1002/anie.202207002</a>.","ieee":"C. Chang <i>et al.</i>, “Surface functionalization of surfactant-free particles: A strategy to tailor the properties of nanocomposites for enhanced thermoelectric performance,” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 35. Wiley, 2022."},"oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"acknowledgement":"This research was supported by the Scientific Service Units (SSU) of IST Austria through resources provided by Electron Microscopy Facility (EMF) and the Nanofabrication Facility (NNF). This work was financially supported by IST Austria and the Werner Siemens Foundation. C.C. acknowledges funding from the FWF “Lise Meitner Fellowship” grant agreement M 2889-N. Lise Meitner Project (M2889-N). Y.L. acknowledges funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No. 754411. R.L.B. thanks the National Science Foundation for support under DMR-1904719. MCS acknowledge MINECO Juan de la Cierva Incorporation fellowship (JdlCI 2019) and Severo Ochoa. M.C.S. and J.A. acknowledge funding from Generalitat de Catalunya 2017 SGR 327. ICN2 is supported by the Severo Ochoa program from Spanish MINECO (Grant no. SEV-2017-0706) and is funded by the CERCA Programme/Generalitat de Catalunya. This study was supported by MCIN with funding from European Union NextGenerationEU (PRTR-C17.I1) and Generalitat de Catalunya.","issue":"35","language":[{"iso":"eng"}],"ec_funded":1,"publication":"Angewandte Chemie International Edition","ddc":["540"],"project":[{"_id":"9B8804FC-BA93-11EA-9121-9846C619BF3A","name":"Bottom-up Engineering for Thermoelectric Applications","grant_number":"M02889"},{"_id":"260C2330-B435-11E9-9278-68D0E5697425","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020"}],"scopus_import":"1","article_type":"original","day":"26","abstract":[{"text":"The broad implementation of thermoelectricity requires high-performance and low-cost materials. One possibility is employing surfactant-free solution synthesis to produce nanopowders. We propose the strategy of functionalizing “naked” particles’ surface by inorganic molecules to control the nanostructure and, consequently, thermoelectric performance. In particular, we use bismuth thiolates to functionalize surfactant-free SnTe particles’ surfaces. Upon thermal processing, bismuth thiolates decomposition renders SnTe-Bi2S3 nanocomposites with synergistic functions: 1) carrier concentration optimization by Bi doping; 2) Seebeck coefficient enhancement and bipolar effect suppression by energy filtering; and 3) lattice thermal conductivity reduction by small grain domains, grain boundaries and nanostructuration. Overall, the SnTe-Bi2S3 nanocomposites exhibit peak z T up to 1.3 at 873 K and an average z T of ≈0.6 at 300–873 K, which is among the highest reported for solution-processed SnTe.","lang":"eng"}],"volume":61},{"das_tickbox":"1","fulldoi":"https://doi.org/10.1002/anie.202207013","type":"journal_article","date_published":"2022-08-01T00:00:00Z","pmid":1,"related_material":{"record":[{"status":"public","id":"11695","relation":"research_data"}]},"date_created":"2022-06-19T22:01:58Z","external_id":{"pmid":["35612297"],"isi":["000811084000001"]},"article_number":"e202207013","month":"08","article_processing_charge":"No","department":[{"_id":"MaIb"}],"publication_status":"published","title":"The chemistry of Cu₃N and Cu₃PdN nanocrystals","date_updated":"2026-07-08T05:53:27Z","year":"2022","doi":"10.1002/anie.202207013","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","has_accepted_license":"1","isi":1,"_id":"11451","publisher":"Wiley","intvolume":"        61","author":[{"first_name":"Mahsa","full_name":"Parvizian, Mahsa","last_name":"Parvizian"},{"last_name":"Duràn Balsa","full_name":"Duràn Balsa, Alejandra","first_name":"Alejandra"},{"first_name":"Rohan","last_name":"Pokratath","full_name":"Pokratath, Rohan"},{"full_name":"Kalha, Curran","last_name":"Kalha","first_name":"Curran"},{"id":"BB243B88-D767-11E9-B658-BC13E6697425","first_name":"Seungho","orcid":"0000-0002-6962-8598","last_name":"Lee","full_name":"Lee, Seungho"},{"last_name":"Van Den Eynden","full_name":"Van Den Eynden, Dietger","first_name":"Dietger"},{"full_name":"Ibáñez, Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","first_name":"Maria","id":"43C61214-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Anna","full_name":"Regoutz, Anna","last_name":"Regoutz"},{"last_name":"De Roo","full_name":"De Roo, Jonathan","first_name":"Jonathan"}],"oa":1,"language":[{"iso":"eng"}],"acknowledgement":"J.D.R. and M.P. acknowledge the SNF Eccellenza funding scheme (project number: 194172). We acknowledge DESY (Hamburg, Germany), a member of the Helmholtz Association HGF, for the provision of experimental facilities. Parts of this research were carried out at beamline P21.1, PETRA III. We thank Dr. Soham Banerjee for acquiring the PDF data and helpful advice. A.R. acknowledges the support from the Analytical Chemistry Trust Fund for her CAMS-UK Fellowship. C.K. acknowledges the support from the Department of Chemistry, UCL. The authors acknowledge Dr Stephan Lany from NREL for providing the Cu3N DFT calculations. The authors thank Prof. Raymond Schaak and Dr. Robert William Lord for helpful advice and suggestions regarding the purification procedure. Open access funding provided by Universitat Basel.","issue":"31","oa_version":"Published Version","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"citation":{"short":"M. Parvizian, A. Duràn Balsa, R. Pokratath, C. Kalha, S. Lee, D. Van Den Eynden, M. Ibáñez, A. Regoutz, J. De Roo, Angewandte Chemie International Edition 61 (2022).","apa":"Parvizian, M., Duràn Balsa, A., Pokratath, R., Kalha, C., Lee, S., Van Den Eynden, D., … De Roo, J. (2022). The chemistry of Cu₃N and Cu₃PdN nanocrystals. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202207013\">https://doi.org/10.1002/anie.202207013</a>","chicago":"Parvizian, Mahsa, Alejandra Duràn Balsa, Rohan Pokratath, Curran Kalha, Seungho Lee, Dietger Van Den Eynden, Maria Ibáñez, Anna Regoutz, and Jonathan De Roo. “The Chemistry of Cu₃N and Cu₃PdN Nanocrystals.” <i>Angewandte Chemie International Edition</i>. Wiley, 2022. <a href=\"https://doi.org/10.1002/anie.202207013\">https://doi.org/10.1002/anie.202207013</a>.","ieee":"M. Parvizian <i>et al.</i>, “The chemistry of Cu₃N and Cu₃PdN nanocrystals,” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 31. Wiley, 2022.","ama":"Parvizian M, Duràn Balsa A, Pokratath R, et al. The chemistry of Cu₃N and Cu₃PdN nanocrystals. <i>Angewandte Chemie International Edition</i>. 2022;61(31). doi:<a href=\"https://doi.org/10.1002/anie.202207013\">10.1002/anie.202207013</a>","mla":"Parvizian, Mahsa, et al. “The Chemistry of Cu₃N and Cu₃PdN Nanocrystals.” <i>Angewandte Chemie International Edition</i>, vol. 61, no. 31, e202207013, Wiley, 2022, doi:<a href=\"https://doi.org/10.1002/anie.202207013\">10.1002/anie.202207013</a>.","ista":"Parvizian M, Duràn Balsa A, Pokratath R, Kalha C, Lee S, Van Den Eynden D, Ibáñez M, Regoutz A, De Roo J. 2022. The chemistry of Cu₃N and Cu₃PdN nanocrystals. Angewandte Chemie International Edition. 61(31), e202207013."},"publication_identifier":{"issn":["1433-7851"],"eissn":["1521-3773"]},"file":[{"file_name":"2022_AngewandteChemieInternat_Parvizian.pdf","checksum":"2a3ee0bb59e044b808ebe85cd94ac899","date_created":"2022-07-29T09:29:20Z","content_type":"application/pdf","access_level":"open_access","success":1,"date_updated":"2022-07-29T09:29:20Z","file_size":1303202,"relation":"main_file","file_id":"11696","creator":"dernst"}],"file_date_updated":"2022-07-29T09:29:20Z","abstract":[{"text":"The precursor conversion chemistry and surface chemistry of Cu3N and Cu3PdN nanocrystals are unknown or contested. Here, we first obtain phase-pure, colloidally stable nanocubes. Second, we elucidate the pathway by which copper(II) nitrate and oleylamine form Cu3N. We find that oleylamine is both a reductant and a nitrogen source. Oleylamine is oxidized by nitrate to a primary aldimine, which reacts further with excess oleylamine to a secondary aldimine, eliminating ammonia. Ammonia reacts with CuI to form Cu3N. Third, we investigated the surface chemistry and find a mixed ligand shell of aliphatic amines and carboxylates (formed in situ). While the carboxylates appear tightly bound, the amines are easily desorbed from the surface. Finally, we show that doping with palladium decreases the band gap and the material becomes semi-metallic. These results bring insight into the chemistry of metal nitrides and might help the development of other metal nitride nanocrystals.","lang":"eng"}],"volume":61,"scopus_import":"1","article_type":"original","day":"01","publication":"Angewandte Chemie International Edition","ddc":["540"]},{"author":[{"last_name":"Parvizian","full_name":"Parvizian, Mahsa","first_name":"Mahsa"},{"first_name":"Alejandra","last_name":"Duran Balsa","full_name":"Duran Balsa, Alejandra"},{"first_name":"Rohan","full_name":"Pokratath, Rohan","last_name":"Pokratath"},{"first_name":"Curran","full_name":"Kalha, Curran","last_name":"Kalha"},{"full_name":"Lee, Seungho","last_name":"Lee","first_name":"Seungho"},{"first_name":"Dietger","last_name":"Van den Eynden","full_name":"Van den Eynden, Dietger"},{"orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","full_name":"Ibáñez, Maria","last_name":"Ibáñez"},{"first_name":"Anna","last_name":"Regoutz","full_name":"Regoutz, Anna"},{"last_name":"De Roo","full_name":"De Roo, Jonathan","first_name":"Jonathan"}],"oa":1,"ddc":["540"],"publisher":"Zenodo","_id":"11695","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","status":"public","day":"12","title":"Data for \"The chemistry of Cu3N and Cu3PdN nanocrystals\"","year":"2022","date_updated":"2026-07-08T05:53:27Z","abstract":[{"text":"Data underlying the figures in the publication \"The chemistry of Cu3N and Cu3PdN nanocrystals\" ","lang":"eng"}],"doi":"10.5281/ZENODO.6542908","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5281/ZENODO.6542908"}],"article_processing_charge":"No","month":"05","department":[{"_id":"MaIb"}],"date_created":"2022-07-29T09:31:13Z","citation":{"ieee":"M. Parvizian <i>et al.</i>, “Data for ‘The chemistry of Cu3N and Cu3PdN nanocrystals.’” Zenodo, 2022.","chicago":"Parvizian, Mahsa, Alejandra Duran Balsa, Rohan Pokratath, Curran Kalha, Seungho Lee, Dietger Van den Eynden, Maria Ibáñez, Anna Regoutz, and Jonathan De Roo. “Data for ‘The Chemistry of Cu3N and Cu3PdN Nanocrystals.’” Zenodo, 2022. <a href=\"https://doi.org/10.5281/ZENODO.6542908\">https://doi.org/10.5281/ZENODO.6542908</a>.","short":"M. Parvizian, A. Duran Balsa, R. Pokratath, C. Kalha, S. Lee, D. Van den Eynden, M. Ibáñez, A. Regoutz, J. De Roo, (2022).","apa":"Parvizian, M., Duran Balsa, A., Pokratath, R., Kalha, C., Lee, S., Van den Eynden, D., … De Roo, J. (2022). Data for “The chemistry of Cu3N and Cu3PdN nanocrystals.” Zenodo. <a href=\"https://doi.org/10.5281/ZENODO.6542908\">https://doi.org/10.5281/ZENODO.6542908</a>","mla":"Parvizian, Mahsa, et al. <i>Data for “The Chemistry of Cu3N and Cu3PdN Nanocrystals.”</i> Zenodo, 2022, doi:<a href=\"https://doi.org/10.5281/ZENODO.6542908\">10.5281/ZENODO.6542908</a>.","ista":"Parvizian M, Duran Balsa A, Pokratath R, Kalha C, Lee S, Van den Eynden D, Ibáñez M, Regoutz A, De Roo J. 2022. Data for ‘The chemistry of Cu3N and Cu3PdN nanocrystals’, Zenodo, <a href=\"https://doi.org/10.5281/ZENODO.6542908\">10.5281/ZENODO.6542908</a>.","ama":"Parvizian M, Duran Balsa A, Pokratath R, et al. Data for “The chemistry of Cu3N and Cu3PdN nanocrystals.” 2022. doi:<a href=\"https://doi.org/10.5281/ZENODO.6542908\">10.5281/ZENODO.6542908</a>"},"related_material":{"record":[{"relation":"used_in_publication","id":"11451","status":"public"}]},"oa_version":"Published Version","type":"research_data_reference","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_published":"2022-05-12T00:00:00Z","fulldoi":"https://doi.org/10.5281/ZENODO.6542908"},{"publication":"Physical Review Research","ddc":["530"],"researchdata_availability":"no","article_type":"original","day":"10","scopus_import":"1","volume":4,"supplementarymaterial":"no","abstract":[{"text":"Finding a feasible scheme for testing the quantum mechanical nature of the gravitational interaction has been attracting an increasing level of attention. Gravity mediated entanglement generation so far appears to be the key ingredient for a potential experiment. In a recent proposal [D. Carney et al., PRX Quantum 2, 030330 (2021)] combining an atom interferometer with a low-frequency mechanical oscillator, a coherence revival test is proposed for verifying this entanglement generation. With measurements performed only on the atoms, this protocol bypasses the need for correlation measurements. Here, we explore formulations of such a protocol, and specifically find that in the envisioned regime of operation with high thermal excitation, semiclassical models, where there is no concept of entanglement, also give the same experimental signatures. We elucidate in a fully quantum mechanical calculation that entanglement is not the source of the revivals in the relevant parameter regime. We argue that, in its current form, the suggested test is only relevant if the oscillator is nearly in a pure quantum state, and in this regime the effects are too small to be measurable. We further discuss potential open ends. The results highlight the importance and subtleties of explicitly considering how the quantum case differs from the classical expectations when testing for the quantum mechanical nature of a physical system.","lang":"eng"}],"file_date_updated":"2022-01-24T11:12:44Z","file":[{"content_type":"application/pdf","date_created":"2022-01-24T11:12:44Z","checksum":"7254d267a0633ca5d63131d345e58686","file_name":"2022_PhysRevResearch_Hosten.pdf","creator":"cchlebak","file_id":"10660","relation":"main_file","file_size":236329,"date_updated":"2022-01-24T11:12:44Z","success":1,"access_level":"open_access"}],"publication_identifier":{"issn":["2643-1564"]},"citation":{"ieee":"O. Hosten, “Constraints on probing quantum coherence to infer gravitational entanglement,” <i>Physical Review Research</i>, vol. 4, no. 1. American Physical Society, 2022.","chicago":"Hosten, Onur. “Constraints on Probing Quantum Coherence to Infer Gravitational Entanglement.” <i>Physical Review Research</i>. American Physical Society, 2022. <a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">https://doi.org/10.1103/PhysRevResearch.4.013023</a>.","short":"O. Hosten, Physical Review Research 4 (2022).","apa":"Hosten, O. (2022). Constraints on probing quantum coherence to infer gravitational entanglement. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">https://doi.org/10.1103/PhysRevResearch.4.013023</a>","mla":"Hosten, Onur. “Constraints on Probing Quantum Coherence to Infer Gravitational Entanglement.” <i>Physical Review Research</i>, vol. 4, no. 1, 013023, American Physical Society, 2022, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">10.1103/PhysRevResearch.4.013023</a>.","ista":"Hosten O. 2022. Constraints on probing quantum coherence to infer gravitational entanglement. Physical Review Research. 4(1), 013023.","ama":"Hosten O. Constraints on probing quantum coherence to infer gravitational entanglement. <i>Physical Review Research</i>. 2022;4(1). doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">10.1103/PhysRevResearch.4.013023</a>"},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","issue":"1","acknowledgement":"O.H. is supported by Institute of Science and Technology Austria. The author thanks Jess Riedel for discussions.","language":[{"iso":"eng"}],"corr_author":"1","author":[{"full_name":"Hosten, Onur","last_name":"Hosten","orcid":"0000-0002-2031-204X","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","first_name":"Onur"}],"oa":1,"publisher":"American Physical Society","intvolume":"         4","_id":"10652","status":"public","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","quality_controlled":"1","has_accepted_license":"1","doi":"10.1103/PhysRevResearch.4.013023","title":"Constraints on probing quantum coherence to infer gravitational entanglement","date_updated":"2026-07-08T08:47:19Z","year":"2022","publication_status":"published","department":[{"_id":"OnHo"}],"month":"01","article_processing_charge":"Yes (via OA deal)","article_number":"013023","date_created":"2022-01-23T23:01:27Z","date_published":"2022-01-10T00:00:00Z","type":"journal_article","fulldoi":"https://doi.org/10.1103/PhysRevResearch.4.013023","das_tickbox":"0"},{"citation":{"short":"B. Prach, C. Lampert, in:, Computer Vision – ECCV 2022, Springer Nature, 2022, pp. 350–365.","apa":"Prach, B., &#38; Lampert, C. (2022). Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In <i>Computer Vision – ECCV 2022</i> (Vol. 13681, pp. 350–365). Tel Aviv, Israel: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>","ieee":"B. Prach and C. Lampert, “Almost-orthogonal layers for efficient general-purpose Lipschitz networks,” in <i>Computer Vision – ECCV 2022</i>, Tel Aviv, Israel, 2022, vol. 13681, pp. 350–365.","chicago":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” In <i>Computer Vision – ECCV 2022</i>, 13681:350–65. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>.","ama":"Prach B, Lampert C. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In: <i>Computer Vision – ECCV 2022</i>. Vol 13681. Springer Nature; 2022:350-365. doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>","mla":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” <i>Computer Vision – ECCV 2022</i>, vol. 13681, Springer Nature, 2022, pp. 350–65, doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>.","ista":"Prach B, Lampert C. 2022. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. Computer Vision – ECCV 2022. ECCV: European Conference on Computer Vision, LNCS, vol. 13681, 350–365."},"publication_identifier":{"isbn":["9783031198021"],"eisbn":["9783031198038"]},"oa_version":"Preprint","language":[{"iso":"eng"}],"publication":"Computer Vision – ECCV 2022","page":"350-365","volume":13681,"alternative_title":["LNCS"],"abstract":[{"text":"It is a highly desirable property for deep networks to be robust against\r\nsmall input changes. One popular way to achieve this property is by designing\r\nnetworks with a small Lipschitz constant. In this work, we propose a new\r\ntechnique for constructing such Lipschitz networks that has a number of\r\ndesirable properties: it can be applied to any linear network layer\r\n(fully-connected or convolutional), it provides formal guarantees on the\r\nLipschitz constant, it is easy to implement and efficient to run, and it can be\r\ncombined with any training objective and optimization method. In fact, our\r\ntechnique is the first one in the literature that achieves all of these\r\nproperties simultaneously. Our main contribution is a rescaling-based weight\r\nmatrix parametrization that guarantees each network layer to have a Lipschitz\r\nconstant of at most 1 and results in the learned weight matrices to be close to\r\northogonal. Hence we call such layers almost-orthogonal Lipschitz (AOL).\r\nExperiments and ablation studies in the context of image classification with\r\ncertified robust accuracy confirm that AOL layers achieve results that are on\r\npar with most existing methods. Yet, they are simpler to implement and more\r\nbroadly applicable, because they do not require computationally expensive\r\nmatrix orthogonalization or inversion steps as part of the network\r\narchitecture. We provide code at https://github.com/berndprach/AOL.","lang":"eng"}],"day":"23","scopus_import":"1","department":[{"_id":"GradSch"},{"_id":"ChLa"}],"month":"10","article_processing_charge":"No","main_file_link":[{"open_access":"1","url":" https://doi.org/10.48550/arXiv.2208.03160"}],"publication_status":"published","date_created":"2022-08-12T15:09:47Z","conference":{"start_date":"2022-10-23","location":"Tel Aviv, Israel","name":"ECCV: European Conference on Computer Vision","end_date":"2022-10-27"},"external_id":{"isi":["000904104000021"],"arxiv":["2208.03160"]},"date_published":"2022-10-23T00:00:00Z","type":"conference","related_material":{"record":[{"relation":"dissertation_contains","id":"19759","status":"public"}]},"arxiv":1,"fulldoi":"https://doi.org/10.1007/978-3-031-19803-8_21","publisher":"Springer Nature","intvolume":"     13681","corr_author":"1","author":[{"id":"2D561D42-C427-11E9-89B4-9C1AE6697425","first_name":"Bernd","full_name":"Prach, Bernd","last_name":"Prach"},{"full_name":"Lampert, Christoph","last_name":"Lampert","orcid":"0000-0001-8622-7887","first_name":"Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87"}],"oa":1,"_id":"11839","isi":1,"doi":"10.1007/978-3-031-19803-8_21","year":"2022","date_updated":"2026-07-27T12:47:43Z","title":"Almost-orthogonal layers for efficient general-purpose Lipschitz networks","quality_controlled":"1","status":"public","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345"},{"doi":"10.1007/978-3-031-17196-3_11","year":"2022","date_updated":"2026-07-27T12:48:18Z","title":"Abstract monitors for quantitative specifications","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","quality_controlled":"1","has_accepted_license":"1","status":"public","_id":"11775","isi":1,"intvolume":"     13498","publisher":"Springer Nature","oa":1,"author":[{"last_name":"Henzinger","full_name":"Henzinger, Thomas A","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2985-7724"},{"first_name":"Nicolas Adrien","id":"b26baa86-3308-11ec-87b0-8990f34baa85","full_name":"Mazzocchi, Nicolas Adrien","last_name":"Mazzocchi"},{"first_name":"Naci E","id":"8C6B42F8-C8E6-11E9-A03A-F2DCE5697425","full_name":"Sarac, Naci E","last_name":"Sarac"}],"corr_author":"1","fulldoi":"https://doi.org/10.1007/978-3-031-17196-3_11","type":"conference","date_published":"2022-09-23T00:00:00Z","related_material":{"record":[{"relation":"dissertation_contains","id":"20147","status":"public"}]},"date_created":"2022-08-08T17:09:09Z","conference":{"location":"Tbilisi, Georgia","start_date":"2022-09-28","end_date":"2022-09-30","name":"RV: Runtime Verification"},"external_id":{"isi":["000866539700011"]},"department":[{"_id":"GradSch"},{"_id":"ToHe"}],"article_processing_charge":"Yes","month":"09","publication_status":"published","alternative_title":["LNCS"],"volume":13498,"abstract":[{"lang":"eng","text":"Quantitative monitoring can be universal and approximate: For every finite sequence of observations, the specification provides a value and the monitor outputs a best-effort approximation of it. The quality of the approximation may depend on the resources that are available to the monitor. By taking to the limit the sequences of specification values and monitor outputs, we obtain precision-resource trade-offs also for limit monitoring. This paper provides a formal framework for studying such trade-offs using an abstract interpretation for monitors: For each natural number n, the aggregate semantics of a monitor at time n is an equivalence relation over all sequences of at most n observations so that two equivalent sequences are indistinguishable to the monitor and thus mapped to the same output. This abstract interpretation of quantitative monitors allows us to measure the number of equivalence classes (or “resource use”) that is necessary for a certain precision up to a certain time, or at any time. Our framework offers several insights. For example, we identify a family of specifications for which any resource-optimal exact limit monitor is independent of any error permitted over finite traces. Moreover, we present a specification for which any resource-optimal approximate limit monitor does not minimize its resource use at any time. "}],"day":"23","scopus_import":"1","project":[{"name":"Vigilant Algorithmic Monitoring of Software","grant_number":"101020093","call_identifier":"H2020","_id":"62781420-2b32-11ec-9570-8d9b63373d4d"}],"ddc":["000"],"publication":"22nd International Conference on Runtime Verification","page":"200-220","ec_funded":1,"language":[{"iso":"eng"}],"acknowledgement":"We thank the anonymous reviewers for their helpful comments. This work was supported in part by the ERC-2020-AdG 101020093.","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"oa_version":"Published Version","citation":{"apa":"Henzinger, T. A., Mazzocchi, N. A., &#38; Sarac, N. E. (2022). Abstract monitors for quantitative specifications. In <i>22nd International Conference on Runtime Verification</i> (Vol. 13498, pp. 200–220). Tbilisi, Georgia: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">https://doi.org/10.1007/978-3-031-17196-3_11</a>","short":"T.A. Henzinger, N.A. Mazzocchi, N.E. Sarac, in:, 22nd International Conference on Runtime Verification, Springer Nature, 2022, pp. 200–220.","ieee":"T. A. Henzinger, N. A. Mazzocchi, and N. E. Sarac, “Abstract monitors for quantitative specifications,” in <i>22nd International Conference on Runtime Verification</i>, Tbilisi, Georgia, 2022, vol. 13498, pp. 200–220.","chicago":"Henzinger, Thomas A, Nicolas Adrien Mazzocchi, and Naci E Sarac. “Abstract Monitors for Quantitative Specifications.” In <i>22nd International Conference on Runtime Verification</i>, 13498:200–220. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">https://doi.org/10.1007/978-3-031-17196-3_11</a>.","ama":"Henzinger TA, Mazzocchi NA, Sarac NE. Abstract monitors for quantitative specifications. In: <i>22nd International Conference on Runtime Verification</i>. Vol 13498. Springer Nature; 2022:200-220. doi:<a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">10.1007/978-3-031-17196-3_11</a>","ista":"Henzinger TA, Mazzocchi NA, Sarac NE. 2022. Abstract monitors for quantitative specifications. 22nd International Conference on Runtime Verification. RV: Runtime Verification, LNCS, vol. 13498, 200–220.","mla":"Henzinger, Thomas A., et al. “Abstract Monitors for Quantitative Specifications.” <i>22nd International Conference on Runtime Verification</i>, vol. 13498, Springer Nature, 2022, pp. 200–20, doi:<a href=\"https://doi.org/10.1007/978-3-031-17196-3_11\">10.1007/978-3-031-17196-3_11</a>."},"publication_identifier":{"issn":["0302-9743"]},"file":[{"content_type":"application/pdf","file_name":"2022_LNCS_RV_Henzinger.pdf","checksum":"05c7dcfbb9053a98f46441fb2eccb213","date_created":"2023-01-20T07:34:50Z","file_size":477110,"file_id":"12317","relation":"main_file","creator":"dernst","access_level":"open_access","success":1,"date_updated":"2023-01-20T07:34:50Z"}],"file_date_updated":"2023-01-20T07:34:50Z"},{"publication":"Plant & Cell Physiology","ddc":["580"],"page":"104-119","volume":63,"abstract":[{"lang":"eng","text":"The synthetic strigolactone (SL) analog, rac-GR24, has been instrumental in studying the role of SLs as well as karrikins because it activates the receptors DWARF14 (D14) and KARRIKIN INSENSITIVE 2 (KAI2) of their signaling pathways, respectively. Treatment with rac-GR24 modifies the root architecture at different levels, such as decreasing the lateral root density (LRD), while promoting root hair elongation or flavonol accumulation. Previously, we have shown that the flavonol biosynthesis is transcriptionally activated in the root by rac-GR24 treatment, but, thus far, the molecular players involved in that response have remained unknown. To get an in-depth insight into the changes that occur after the compound is perceived by the roots, we compared the root transcriptomes of the wild type and the more axillary growth2 (max2) mutant, affected in both SL and karrikin signaling pathways, with and without rac-GR24 treatment. Quantitative reverse transcription (qRT)-PCR, reporter line analysis and mutant phenotyping indicated that the flavonol response and the root hair elongation are controlled by the ELONGATED HYPOCOTYL 5 (HY5) and MYB12 transcription factors, but HY5, in contrast to MYB12, affects the LRD as well. Furthermore, we identified the transcription factors TARGET OF MONOPTEROS 5 (TMO5) and TMO5 LIKE1 as negative and the Mediator complex as positive regulators of the rac-GR24 effect on LRD. Altogether, hereby, we get closer toward understanding the molecular mechanisms that underlay the rac-GR24 responses in the root."}],"article_type":"original","day":"21","scopus_import":"1","keyword":["flavonols","MAX2","rac-Gr24","RNA-seq","root development","transcriptional regulation"],"citation":{"apa":"Struk, S., Braem, L., Matthys, C., Walton, A., Vangheluwe, N., Van Praet, S., … Goormachtig, S. (2022). Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density. <i>Plant &#38; Cell Physiology</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/pcp/pcab149\">https://doi.org/10.1093/pcp/pcab149</a>","short":"S. Struk, L. Braem, C. Matthys, A. Walton, N. Vangheluwe, S. Van Praet, L. Jiang, P. Baster, C. De Cuyper, F.-D. Boyer, E. Stes, T. Beeckman, J. Friml, K. Gevaert, S. Goormachtig, Plant &#38; Cell Physiology 63 (2022) 104–119.","chicago":"Struk, Sylwia, Lukas Braem, Cedrick Matthys, Alan Walton, Nick Vangheluwe, Stan Van Praet, Lingxiang Jiang, et al. “Transcriptional Analysis in the Arabidopsis Roots Reveals New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol Accumulation, Root Hair Elongation and Lateral Root Density.” <i>Plant &#38; Cell Physiology</i>. Oxford University Press, 2022. <a href=\"https://doi.org/10.1093/pcp/pcab149\">https://doi.org/10.1093/pcp/pcab149</a>.","ieee":"S. Struk <i>et al.</i>, “Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density,” <i>Plant &#38; Cell Physiology</i>, vol. 63, no. 1. Oxford University Press, pp. 104–119, 2022.","ama":"Struk S, Braem L, Matthys C, et al. Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density. <i>Plant &#38; Cell Physiology</i>. 2022;63(1):104-119. doi:<a href=\"https://doi.org/10.1093/pcp/pcab149\">10.1093/pcp/pcab149</a>","ista":"Struk S, Braem L, Matthys C, Walton A, Vangheluwe N, Van Praet S, Jiang L, Baster P, De Cuyper C, Boyer F-D, Stes E, Beeckman T, Friml J, Gevaert K, Goormachtig S. 2022. Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density. Plant &#38; Cell Physiology. 63(1), 104–119.","mla":"Struk, Sylwia, et al. “Transcriptional Analysis in the Arabidopsis Roots Reveals New Regulators That Link Rac-GR24 Treatment with Changes in Flavonol Accumulation, Root Hair Elongation and Lateral Root Density.” <i>Plant &#38; Cell Physiology</i>, vol. 63, no. 1, Oxford University Press, 2022, pp. 104–19, doi:<a href=\"https://doi.org/10.1093/pcp/pcab149\">10.1093/pcp/pcab149</a>."},"publication_identifier":{"issn":["0032-0781"],"eissn":["1471-9053"]},"oa_version":"Published Version","language":[{"iso":"eng"}],"issue":"1","acknowledgement":"The authors thank Ralf Stracke (Bielefeld University, Bielefeld, Germany) for providing the myb mutants and their colleagues Bert De Rybel for the tmo5t;mo5l1 double mutant, Boris Parizot for tips on the RNA-seq analysis, Veronique Storme for statistical help on both the RNA-seq and lateral root density, and Martine De Cock for help in preparing the manuscript.","intvolume":"        63","publisher":"Oxford University Press","author":[{"first_name":"Sylwia","last_name":"Struk","full_name":"Struk, Sylwia"},{"first_name":"Lukas","last_name":"Braem","full_name":"Braem, Lukas"},{"last_name":"Matthys","full_name":"Matthys, Cedrick","first_name":"Cedrick"},{"first_name":"Alan","last_name":"Walton","full_name":"Walton, Alan"},{"full_name":"Vangheluwe, Nick","last_name":"Vangheluwe","first_name":"Nick"},{"first_name":"Stan","last_name":"Van Praet","full_name":"Van Praet, Stan"},{"first_name":"Lingxiang","last_name":"Jiang","full_name":"Jiang, Lingxiang"},{"id":"3028BD74-F248-11E8-B48F-1D18A9856A87","first_name":"Pawel","full_name":"Baster, Pawel","last_name":"Baster"},{"full_name":"De Cuyper, Carolien","last_name":"De Cuyper","first_name":"Carolien"},{"first_name":"Francois-Didier","last_name":"Boyer","full_name":"Boyer, Francois-Didier"},{"full_name":"Stes, Elisabeth","last_name":"Stes","first_name":"Elisabeth"},{"full_name":"Beeckman, Tom","last_name":"Beeckman","first_name":"Tom"},{"first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","last_name":"Friml","full_name":"Friml, Jiří"},{"last_name":"Gevaert","full_name":"Gevaert, Kris","first_name":"Kris"},{"last_name":"Goormachtig","full_name":"Goormachtig, Sofie","first_name":"Sofie"}],"oa":1,"_id":"10583","isi":1,"doi":"10.1093/pcp/pcab149","date_updated":"2026-07-28T12:02:02Z","year":"2022","title":"Transcriptional analysis in the Arabidopsis roots reveals new regulators that link rac-GR24 treatment with changes in flavonol accumulation, root hair elongation and lateral root density","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","OA_type":"free access","department":[{"_id":"JiFr"}],"month":"01","article_processing_charge":"No","main_file_link":[{"url":"https://doi.org/10.1093/pcp/pcab149","open_access":"1"}],"publication_status":"published","date_created":"2021-12-28T11:44:18Z","external_id":{"pmid":["34791413"],"isi":["000877899400009"]},"type":"journal_article","date_published":"2022-01-21T00:00:00Z","pmid":1,"fulldoi":"https://doi.org/10.1093/pcp/pcab149"},{"fulldoi":"https://doi.org/10.1111/nph.17792","biorxivid":1,"pmid":1,"type":"journal_article","date_published":"2022-01-01T00:00:00Z","external_id":{"pmid":["34637542"],"biorxivid":["10.1101/2020.05.02.074070"],"isi":["000714678100001"]},"date_created":"2021-11-14T23:01:24Z","main_file_link":[{"url":"https://doi.org/10.1111/nph.17792","open_access":"1"}],"publication_status":"published","OA_type":"free access","department":[{"_id":"JiFr"}],"article_processing_charge":"No","OA_place":"publisher","month":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","status":"public","doi":"10.1111/nph.17792","year":"2022","date_updated":"2026-07-28T12:06:20Z","title":"Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana","_id":"10282","isi":1,"author":[{"full_name":"Kashkan, Ivan","last_name":"Kashkan","first_name":"Ivan"},{"first_name":"Mónika","id":"45A71A74-F248-11E8-B48F-1D18A9856A87","full_name":"Hrtyan, Mónika","last_name":"Hrtyan"},{"first_name":"Katarzyna","last_name":"Retzer","full_name":"Retzer, Katarzyna"},{"first_name":"Jana","last_name":"Humpolíčková","full_name":"Humpolíčková, Jana"},{"first_name":"Aswathy","full_name":"Jayasree, Aswathy","last_name":"Jayasree"},{"first_name":"Roberta","full_name":"Filepová, Roberta","last_name":"Filepová"},{"last_name":"Vondráková","full_name":"Vondráková, Zuzana","first_name":"Zuzana"},{"full_name":"Simon, Sibu","last_name":"Simon","orcid":"0000-0002-1998-6741","first_name":"Sibu","id":"4542EF9A-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Rombaut, Debbie","last_name":"Rombaut","first_name":"Debbie"},{"first_name":"Thomas B.","last_name":"Jacobs","full_name":"Jacobs, Thomas B."},{"full_name":"Frilander, Mikko J.","last_name":"Frilander","first_name":"Mikko J."},{"last_name":"Hejátko","full_name":"Hejátko, Jan","first_name":"Jan"},{"full_name":"Friml, Jiří","last_name":"Friml","orcid":"0000-0002-8302-7596","first_name":"Jiří","id":"4159519E-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Jan","full_name":"Petrášek, Jan","last_name":"Petrášek"},{"first_name":"Kamil","full_name":"Růžička, Kamil","last_name":"Růžička"}],"oa":1,"intvolume":"       233","publisher":"Wiley","issue":"1","acknowledgement":"We thank Claus Schwechheimer for the pin34 and pin347 seeds, Yuliia Mironova for technical assistance, Ksenia Timofeyenko and Dmitry Konovalov for help with the evolutional analysis, Konstantin Kutashev and Siarhei Dabravolski for assistance with FRET-FLIM, Huibin Han for advice with hypocotyl imaging, Karel Müller for the initial qRT-PCR on the tobacco cell lines, Stano Pekár for suggestions regarding the statistical analysis of the morphodynamic measurements, and Jozef Mravec, Dolf Weijers and Lindy Abas for their comments on the manuscript. This work was supported by the Czech Science Foundation (projects 16-26428S and 19-23773S to IK, MH and KRůžička, 19-18917S to JHumpolíčková and 18-26981S to JF), and the Ministry of Education, Youth and Sports of the Czech Republic (MEYS, CZ.02.1.01/0.0/0.0/16_019/0000738) to KRůžička and JHejátko. The imaging facilities of the Institute of Experimental Botany and CEITEC are supported by MEYS (LM2018129 – Czech BioImaging and CZ.02.1.01/0.0/0.0/16_013/0001775). The authors declare no competing interests.","language":[{"iso":"eng"}],"oa_version":"Published Version","publication_identifier":{"issn":["0028-646X"],"eissn":["1469-8137"]},"citation":{"ista":"Kashkan I, Hrtyan M, Retzer K, Humpolíčková J, Jayasree A, Filepová R, Vondráková Z, Simon S, Rombaut D, Jacobs TB, Frilander MJ, Hejátko J, Friml J, Petrášek J, Růžička K. 2022. Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana. New Phytologist. 233(1), 329–343.","mla":"Kashkan, Ivan, et al. “Mutually Opposing Activity of PIN7 Splicing Isoforms Is Required for Auxin-Mediated Tropic Responses in Arabidopsis Thaliana.” <i>New Phytologist</i>, vol. 233, no. 1, Wiley, 2022, pp. 329–43, doi:<a href=\"https://doi.org/10.1111/nph.17792\">10.1111/nph.17792</a>.","ama":"Kashkan I, Hrtyan M, Retzer K, et al. Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana. <i>New Phytologist</i>. 2022;233(1):329-343. doi:<a href=\"https://doi.org/10.1111/nph.17792\">10.1111/nph.17792</a>","chicago":"Kashkan, Ivan, Mónika Hrtyan, Katarzyna Retzer, Jana Humpolíčková, Aswathy Jayasree, Roberta Filepová, Zuzana Vondráková, et al. “Mutually Opposing Activity of PIN7 Splicing Isoforms Is Required for Auxin-Mediated Tropic Responses in Arabidopsis Thaliana.” <i>New Phytologist</i>. Wiley, 2022. <a href=\"https://doi.org/10.1111/nph.17792\">https://doi.org/10.1111/nph.17792</a>.","ieee":"I. Kashkan <i>et al.</i>, “Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana,” <i>New Phytologist</i>, vol. 233, no. 1. Wiley, pp. 329–343, 2022.","apa":"Kashkan, I., Hrtyan, M., Retzer, K., Humpolíčková, J., Jayasree, A., Filepová, R., … Růžička, K. (2022). Mutually opposing activity of PIN7 splicing isoforms is required for auxin-mediated tropic responses in Arabidopsis thaliana. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.17792\">https://doi.org/10.1111/nph.17792</a>","short":"I. Kashkan, M. Hrtyan, K. Retzer, J. Humpolíčková, A. Jayasree, R. Filepová, Z. Vondráková, S. Simon, D. Rombaut, T.B. Jacobs, M.J. Frilander, J. Hejátko, J. Friml, J. Petrášek, K. Růžička, New Phytologist 233 (2022) 329–343."},"day":"01","article_type":"original","scopus_import":"1","volume":233,"abstract":[{"text":"Advanced transcriptome sequencing has revealed that the majority of eukaryotic genes undergo alternative splicing (AS). Nonetheless, little effort has been dedicated to investigating the functional relevance of particular splicing events, even those in the key developmental and hormonal regulators. Combining approaches of genetics, biochemistry and advanced confocal microscopy, we describe the impact of alternative splicing on the PIN7 gene in the model plant Arabidopsis thaliana. PIN7 encodes a polarly localized transporter for the phytohormone auxin and produces two evolutionarily conserved transcripts, PIN7a and PIN7b. PIN7a and PIN7b, differing in a four amino acid stretch, exhibit almost identical expression patterns and subcellular localization. We reveal that they are closely associated and mutually influence each other's mobility within the plasma membrane. Phenotypic complementation tests indicate that the functional contribution of PIN7b per se is minor, but it markedly reduces the prominent PIN7a activity, which is required for correct seedling apical hook formation and auxin-mediated tropic responses. Our results establish alternative splicing of the PIN family as a conserved, functionally relevant mechanism, revealing an additional regulatory level of auxin-mediated plant development.","lang":"eng"}],"page":"329-343","publication":"New Phytologist"}]