[{"acknowledgement":"This project was supported by the All May See Foundation 7031,182 to YI, the Louisiana Board of Regents Support Fund: Research Competitiveness Subprogram to MAT, Austrian science fund (FWF) as part of the SFB Meiosis consortium FWF SFB F88-10 to Beatriz Vicoso (supported ME), American Heart Association 16POST2726018 and American Cancer Society 132,123-PF-18–025–01-CSM postdoctoral fellowships to ALZ, National Institutes of Health R01 GM136961 and R35 GM148485 to SH-B, and the Academy of Medical Sciences/the Wellcome Trust/ the Government Department of Business, Energy and Industrial Strategy/the British Heart Foundation/Diabetes UK Springboard Award SBF008\\1115 to YM. \r\nComputational analyses of single-nucleus transcriptome data were performed on the high performance computer (HPC) at Bournemouth University, the HPC at Institute of Science and Technology Austria, and the high-performance computational resources provided by the Louisiana Optical Network Infrastructure (http://www.loni.org). The authors are grateful to the researchers who published the transcriptome datasets [48,49,52,55] that became the essential bases for this study, to FlyBase for curating the datasets in an easily accessible format, and the Drosophila Genomics Resource Center (DGRC), supported by NIH grant 2P40OD010949, for providing the D17 cell line used in this research. The authors thank Kristian Koski (University of Oulu, Finland) for crucial advice on the domain structure of collagen P4H⍺s, and Ryusuke Niwa and Ryo Hoshino (University of Tsukuba, Japan) for helpful discussions on SP.","has_accepted_license":"1","file":[{"relation":"main_file","access_level":"open_access","date_created":"2026-01-05T13:09:01Z","file_size":5844254,"checksum":"764257db41865d19daec1935788f72d7","success":1,"file_name":"2025_MatrixBiology_Ishikawa.pdf","file_id":"20948","date_updated":"2026-01-05T13:09:01Z","content_type":"application/pdf","creator":"dernst"}],"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","isi":1,"pmid":1,"author":[{"first_name":"Yoshihiro","last_name":"Ishikawa","full_name":"Ishikawa, Yoshihiro"},{"first_name":"Melissa A","last_name":"Toups","orcid":"0000-0002-9752-7380","full_name":"Toups, Melissa A","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Elkrewi, Marwan N","id":"0B46FACA-A8E1-11E9-9BD3-79D1E5697425","orcid":"0000-0002-5328-7231","first_name":"Marwan N","last_name":"Elkrewi"},{"full_name":"Zajac, Allison L.","last_name":"Zajac","first_name":"Allison L."},{"full_name":"Horne-Badovinac, Sally","last_name":"Horne-Badovinac","first_name":"Sally"},{"full_name":"Matsubayashi, Yutaka","last_name":"Matsubayashi","first_name":"Yutaka"}],"external_id":{"isi":["001583892100002"],"pmid":["40946811"]},"publication_identifier":{"issn":["0945-053X"],"eissn":["1569-1802"]},"issue":"11","intvolume":"       141","_id":"20404","project":[{"grant_number":"F8810","_id":"34ae1506-11ca-11ed-8bc3-c14f4c474396","name":"The highjacking of meiosis for asexual reproduction"}],"quality_controlled":"1","date_published":"2025-11-01T00:00:00Z","status":"public","month":"11","page":"101-113","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_created":"2025-09-28T22:01:26Z","department":[{"_id":"BeVi"}],"citation":{"ista":"Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi Y. 2025. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. Matrix Biology. 141(11), 101–113.","short":"Y. Ishikawa, M.A. Toups, M.N. Elkrewi, A.L. Zajac, S. Horne-Badovinac, Y. Matsubayashi, Matrix Biology 141 (2025) 101–113.","mla":"Ishikawa, Yoshihiro, et al. “Evidence for the Major Role of PH4⍺EFB in the Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>, vol. 141, no. 11, Springer Nature, 2025, pp. 101–13, doi:<a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">10.1016/j.matbio.2025.09.002</a>.","chicago":"Ishikawa, Yoshihiro, Melissa A Toups, Marwan N Elkrewi, Allison L. Zajac, Sally Horne-Badovinac, and Yutaka Matsubayashi. “Evidence for the Major Role of PH4⍺EFB in the Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">https://doi.org/10.1016/j.matbio.2025.09.002</a>.","ama":"Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi Y. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. <i>Matrix Biology</i>. 2025;141(11):101-113. doi:<a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">10.1016/j.matbio.2025.09.002</a>","ieee":"Y. Ishikawa, M. A. Toups, M. N. Elkrewi, A. L. Zajac, S. Horne-Badovinac, and Y. Matsubayashi, “Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV,” <i>Matrix Biology</i>, vol. 141, no. 11. Springer Nature, pp. 101–113, 2025.","apa":"Ishikawa, Y., Toups, M. A., Elkrewi, M. N., Zajac, A. L., Horne-Badovinac, S., &#38; Matsubayashi, Y. (2025). Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV. <i>Matrix Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1016/j.matbio.2025.09.002\">https://doi.org/10.1016/j.matbio.2025.09.002</a>"},"publisher":"Springer Nature","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Collagens are fundamental components of extracellular matrices, requiring precise intracellular post-translational modifications for proper function. Among the modifications, prolyl 4-hydroxylation is critical to stabilise the collagen triple helix. In humans, this reaction is mediated by collagen prolyl 4-hydroxylases (P4Hs). While humans possess three genes encoding these enzymes (P4H⍺s), Drosophila melanogaster harbour at least 26 candidates for collagen P4H⍺s despite its simple genome, and it is poorly understood which of them are actually working on collagen in the fly. In this study, we addressed this question by carrying out thorough bioinformatic and biochemical analyses. We demonstrate that among the 26 potential collagen P4H⍺s, PH4⍺EFB shares the highest homology with vertebrate collagen P4H⍺s. Furthermore, while collagen P4Hs and their substrates must exist in the same cells, our transcriptomic analyses at the tissue and single cell levels showed a global co-expression of PH4⍺EFB but not the other P4H⍺-related genes with the collagen IV genes. Moreover, expression of PH4⍺EFB during embryogenesis was found to precede that of collagen IV, presumably enabling efficient collagen modification by PH4⍺EFB. Finally, biochemical assays confirm that PH4⍺EFB binds collagen, supporting its direct role in collagen IV modification. Collectively, we identify PH4⍺EFB as the primary and potentially constitutive prolyl 4-hydroxylase responsible for collagen IV biosynthesis in Drosophila. Our findings highlight the remarkably simple nature of Drosophila collagen IV biosynthesis, which may serve as a blueprint for defining the minimal requirements for collagen engineering."}],"day":"01","OA_type":"hybrid","oa":1,"volume":141,"title":"Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila collagen IV","year":"2025","doi":"10.1016/j.matbio.2025.09.002","publication_status":"published","file_date_updated":"2026-01-05T13:09:01Z","ddc":["570"],"scopus_import":"1","PlanS_conform":"1","date_updated":"2026-01-05T13:09:08Z","type":"journal_article","publication":"Matrix Biology","article_processing_charge":"Yes (in subscription journal)","article_type":"original"},{"has_accepted_license":"1","acknowledgement":"A.G.V. thanks Peter Balling for useful discussions. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Electron Microscopy Facility (EMF), and by the Werner Siemens Foundation (WSS) for financial support.","file":[{"file_name":"2025_ACSPhotonics_Lorenc.pdf","file_size":6609950,"success":1,"checksum":"d42476279287a9a2f8aeafaef032f4a7","access_level":"open_access","relation":"main_file","date_created":"2025-10-20T11:02:21Z","content_type":"application/pdf","creator":"dernst","date_updated":"2025-10-20T11:02:21Z","file_id":"20502"}],"author":[{"id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87","full_name":"Lorenc, Dusan","last_name":"Lorenc","first_name":"Dusan"},{"first_name":"Artem","last_name":"Volosniev","orcid":"0000-0003-0393-5525","id":"37D278BC-F248-11E8-B48F-1D18A9856A87","full_name":"Volosniev, Artem"},{"last_name":"Zhumekenov","first_name":"Ayan A.","full_name":"Zhumekenov, Ayan A."},{"orcid":"0000-0002-6962-8598","id":"BB243B88-D767-11E9-B658-BC13E6697425","full_name":"Lee, Seungho","first_name":"Seungho","last_name":"Lee"},{"full_name":"Ibáñez, Maria","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","last_name":"Ibáñez"},{"full_name":"Bakr, Osman M.","first_name":"Osman M.","last_name":"Bakr"},{"last_name":"Lemeshko","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802"},{"orcid":"0000-0002-7183-5203","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","full_name":"Alpichshev, Zhanybek","last_name":"Alpichshev","first_name":"Zhanybek"}],"arxiv":1,"external_id":{"isi":["001547359300001"],"arxiv":["2406.05032"]},"isi":1,"OA_place":"publisher","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-08-11T00:00:00Z","quality_controlled":"1","project":[{"_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A","name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery"}],"intvolume":"        12","issue":"9","publication_identifier":{"eissn":["2330-4022"]},"_id":"20405","citation":{"ista":"Lorenc D, Volosniev A, Zhumekenov AA, Lee S, Ibáñez M, Bakr OM, Lemeshko M, Alpichshev Z. 2025. Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. ACS Photonics. 12(9), 5220–5230.","mla":"Lorenc, Dusan, et al. “Observation of Analogue Dynamic Schwinger Effect and Non-Perturbative Light Sensing in Lead Halide Perovskites.” <i>ACS Photonics</i>, vol. 12, no. 9, American Chemical Society, 2025, pp. 5220–30, doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">10.1021/acsphotonics.5c01360</a>.","short":"D. Lorenc, A. Volosniev, A.A. Zhumekenov, S. Lee, M. Ibáñez, O.M. Bakr, M. Lemeshko, Z. Alpichshev, ACS Photonics 12 (2025) 5220–5230.","chicago":"Lorenc, Dusan, Artem Volosniev, Ayan A. Zhumekenov, Seungho Lee, Maria Ibáñez, Osman M. Bakr, Mikhail Lemeshko, and Zhanybek Alpichshev. “Observation of Analogue Dynamic Schwinger Effect and Non-Perturbative Light Sensing in Lead Halide Perovskites.” <i>ACS Photonics</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">https://doi.org/10.1021/acsphotonics.5c01360</a>.","ama":"Lorenc D, Volosniev A, Zhumekenov AA, et al. Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. <i>ACS Photonics</i>. 2025;12(9):5220-5230. doi:<a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">10.1021/acsphotonics.5c01360</a>","ieee":"D. Lorenc <i>et al.</i>, “Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites,” <i>ACS Photonics</i>, vol. 12, no. 9. American Chemical Society, pp. 5220–5230, 2025.","apa":"Lorenc, D., Volosniev, A., Zhumekenov, A. A., Lee, S., Ibáñez, M., Bakr, O. M., … Alpichshev, Z. (2025). Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites. <i>ACS Photonics</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsphotonics.5c01360\">https://doi.org/10.1021/acsphotonics.5c01360</a>"},"publisher":"American Chemical Society","date_created":"2025-09-28T22:01:26Z","department":[{"_id":"MaIb"},{"_id":"MiLe"},{"_id":"ZhAl"}],"page":"5220-5230","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"status":"public","month":"08","title":"Observation of analogue dynamic Schwinger effect and non-perturbative light sensing in lead halide perovskites","volume":12,"year":"2025","day":"11","OA_type":"hybrid","oa":1,"acknowledged_ssus":[{"_id":"EM-Fac"}],"abstract":[{"text":"Dielectric breakdown of physical vacuum (Schwinger effect) is the textbook demonstration of compatibility of Relativity and Quantum theory. Although observing this effect is still practically unachievable, its analogue generalizations have been shown to be more readily attainable. This paper demonstrates that a gapped Dirac semiconductor, methylammonium lead-bromide perovskite (MAPbBr3), exhibits analogue dynamic Schwinger effect. Tunneling ionization under deep subgap mid-infrared irradiation leads to intense photoluminescence in the visible range, in full agreement with quasi-adiabatic theory. In addition to revealing a gapped extended system suitable for studying the analogue Schwinger effect, this observation holds great potential for nonperturbative field sensing, i.e., sensing electric fields through nonperturbative light-matter interactions. First, this paper illustrates this by measuring the local deviation from the nominally cubic phase of a perovskite single crystal, which can be interpreted in terms of frozen-in fields. Next, it is shown that analogue dynamic Schwinger effect can be used for nonperturbative amplification of nonparametric upconversion process in perovskites driven simultaneously by multiple optical fields. This discovery demonstrates the potential for material response beyond perturbation theory in the tunneling regime, offering extremely sensitive light detection and amplification across an ultrabroad spectral range not accessible by conventional devices.","lang":"eng"}],"corr_author":"1","language":[{"iso":"eng"}],"file_date_updated":"2025-10-20T11:02:21Z","publication_status":"published","doi":"10.1021/acsphotonics.5c01360","date_updated":"2025-12-01T12:59:51Z","PlanS_conform":"1","publication":"ACS Photonics","type":"journal_article","ddc":["540","530"],"scopus_import":"1","article_type":"original","article_processing_charge":"Yes (via OA deal)"},{"department":[{"_id":"JoMa"}],"date_created":"2025-09-28T22:01:27Z","publisher":"EDP Sciences","citation":{"short":"A. De Graaff, H.W. Rix, R.P. Naidu, I. Labbé, B. Wang, J. Leja, J.J. Matthee, H. Katz, J.E. Greene, R.E. Hviding, J. Baggen, R. Bezanson, L.A. Boogaard, G. Brammer, P. Dayal, P. Van Dokkum, A.D. Goulding, M. Hirschmann, M.V. Maseda, I. Mcconachie, T.B. Miller, E. Nelson, P.A. Oesch, D.J. Setton, I. Shivaei, A. Weibel, K.E. Whitaker, C.C. Williams, Astronomy &#38; Astrophysics 701 (2025).","mla":"De Graaff, Anna, et al. “A Remarkable Ruby: Absorption in Dense Gas, Rather than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot at z = 3.5.” <i>Astronomy &#38; Astrophysics</i>, vol. 701, A168, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202554681\">10.1051/0004-6361/202554681</a>.","ista":"De Graaff A, Rix HW, Naidu RP, Labbé I, Wang B, Leja J, Matthee JJ, Katz H, Greene JE, Hviding RE, Baggen J, Bezanson R, Boogaard LA, Brammer G, Dayal P, Van Dokkum P, Goulding AD, Hirschmann M, Maseda MV, Mcconachie I, Miller TB, Nelson E, Oesch PA, Setton DJ, Shivaei I, Weibel A, Whitaker KE, Williams CC. 2025. A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. Astronomy &#38; Astrophysics. 701, A168.","chicago":"De Graaff, Anna, Hans Walter Rix, Rohan P. Naidu, Ivo Labbé, Bingjie Wang, Joel Leja, Jorryt J Matthee, et al. “A Remarkable Ruby: Absorption in Dense Gas, Rather than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot at z = 3.5.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202554681\">https://doi.org/10.1051/0004-6361/202554681</a>.","ama":"De Graaff A, Rix HW, Naidu RP, et al. A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. <i>Astronomy &#38; Astrophysics</i>. 2025;701. doi:<a href=\"https://doi.org/10.1051/0004-6361/202554681\">10.1051/0004-6361/202554681</a>","ieee":"A. De Graaff <i>et al.</i>, “A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.","apa":"De Graaff, A., Rix, H. W., Naidu, R. P., Labbé, I., Wang, B., Leja, J., … Williams, C. C. (2025). A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202554681\">https://doi.org/10.1051/0004-6361/202554681</a>"},"month":"09","status":"public","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"quality_controlled":"1","date_published":"2025-09-01T00:00:00Z","_id":"20406","publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"intvolume":"       701","OA_place":"publisher","isi":1,"external_id":{"isi":["001570450900004"],"arxiv":["2503.16600"]},"arxiv":1,"author":[{"full_name":"De Graaff, Anna","first_name":"Anna","last_name":"De Graaff"},{"first_name":"Hans Walter","last_name":"Rix","full_name":"Rix, Hans Walter"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"full_name":"Labbé, Ivo","last_name":"Labbé","first_name":"Ivo"},{"first_name":"Bingjie","last_name":"Wang","full_name":"Wang, Bingjie"},{"last_name":"Leja","first_name":"Joel","full_name":"Leja, Joel"},{"orcid":"0000-0003-2871-127X","full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","last_name":"Matthee"},{"first_name":"Harley","last_name":"Katz","full_name":"Katz, Harley"},{"full_name":"Greene, Jenny E.","first_name":"Jenny E.","last_name":"Greene"},{"full_name":"Hviding, Raphael E.","last_name":"Hviding","first_name":"Raphael E."},{"full_name":"Baggen, Josephine","last_name":"Baggen","first_name":"Josephine"},{"full_name":"Bezanson, Rachel","first_name":"Rachel","last_name":"Bezanson"},{"last_name":"Boogaard","first_name":"Leindert A.","full_name":"Boogaard, Leindert A."},{"full_name":"Brammer, Gabriel","first_name":"Gabriel","last_name":"Brammer"},{"first_name":"Pratika","last_name":"Dayal","full_name":"Dayal, Pratika"},{"full_name":"Van Dokkum, Pieter","first_name":"Pieter","last_name":"Van Dokkum"},{"first_name":"Andy D.","last_name":"Goulding","full_name":"Goulding, Andy D."},{"full_name":"Hirschmann, Michaela","first_name":"Michaela","last_name":"Hirschmann"},{"first_name":"Michael V.","last_name":"Maseda","full_name":"Maseda, Michael V."},{"last_name":"Mcconachie","first_name":"Ian","full_name":"Mcconachie, Ian"},{"full_name":"Miller, Tim B.","first_name":"Tim B.","last_name":"Miller"},{"full_name":"Nelson, Erica","first_name":"Erica","last_name":"Nelson"},{"full_name":"Oesch, Pascal A.","first_name":"Pascal A.","last_name":"Oesch"},{"first_name":"David J.","last_name":"Setton","full_name":"Setton, David J."},{"full_name":"Shivaei, Irene","last_name":"Shivaei","first_name":"Irene"},{"full_name":"Weibel, Andrea","last_name":"Weibel","first_name":"Andrea"},{"full_name":"Whitaker, Katherine E.","first_name":"Katherine E.","last_name":"Whitaker"},{"full_name":"Williams, Christina C.","last_name":"Williams","first_name":"Christina C."}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","file":[{"relation":"main_file","access_level":"open_access","date_created":"2025-09-29T06:59:14Z","checksum":"cf93d635121dbf4865fd080c517927d0","file_size":1218479,"success":1,"file_name":"2025_AstronomyAstrophysics_deGraaff2.pdf","date_updated":"2025-09-29T06:59:14Z","file_id":"20409","content_type":"application/pdf","creator":"dernst"}],"has_accepted_license":"1","acknowledgement":"We thank the PRIMER team for making their imaging data publicly available immediately. We thank Jaime Villaseñor and Friedrich Röpke for helpful discussions. This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs #1837 and #4233. Support for program #4233 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. REH acknowledges support by the German Aerospace Center (DLR) and the Federal Ministry for Economic Affairs and Energy (BMWi) through program 50OR2403 ‘RUBIES’. This research was supported by the International Space Science Institute (ISSI) in Bern, through ISSI International Team project #562. The Cosmic Dawn Center is funded by the Danish National Research Foundation (DNRF) under grant #140. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant 200020_207349. Support for this work for RPN was provided by NASA through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. TBM was supported by a CIERA fellowship. Open Access funding provided by Max Planck Society.","article_processing_charge":"No","article_type":"original","publication":"Astronomy & Astrophysics","type":"journal_article","PlanS_conform":"1","date_updated":"2026-02-16T12:13:12Z","scopus_import":"1","ddc":["520"],"file_date_updated":"2025-09-29T06:59:14Z","doi":"10.1051/0004-6361/202554681","publication_status":"published","oa":1,"day":"01","OA_type":"diamond","year":"2025","volume":701,"title":"A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5","article_number":"A168","language":[{"iso":"eng"}],"abstract":[{"text":"The origin of the rest-optical emission of compact, red, high-redshift sources known as little red dots (LRDs) poses a major puzzle. If interpreted as starlight, it would imply that LRDs constitute the densest stellar systems in the Universe. However, alternative models suggest active galactic nuclei (AGN) may instead power the rest-optical continuum. Here, we present JWST/NIRSpec, NIRCam, and MIRI observations from the RUBIES and PRIMER programs of The Cliff: a bright LRD at z = 3.55 with an exceptional Balmer break, twice as strong as that of any high-redshift source previously observed. The spectra also reveal broad hydrogen (Hα FWHM ∼ 1500 km s−1) and He I emission, but no significant metal lines. We demonstrate that massive evolved stellar populations cannot explain the observed spectrum, even when considering unusually steep and strong dust attenuation or reasonable variations in the initial mass function. Moreover, the formally best-fit stellar mass and compact size (M* ∼ 1010.5 M⊙,  re ∼ 40 pc) would imply densities at which near-monthly stellar collisions might lead to significant X-ray emission. We argue that the Balmer break, emission lines, and Hα absorption line are instead most plausibly explained by a black hole star (BH*) scenario, in which dense gas surrounds a powerful ionising source. In contrast to recently proposed BH* models of dust-reddened AGN, we show that spectral fits in the rest UV to near-infrared favour an intrinsically redder continuum over strong dust reddening. This may point to a super-Eddington accreting massive black hole or, possibly, the presence of (super)massive stars in a nuclear star cluster. The Cliff is the clearest evidence to date that at least some LRDs are not ultra-dense massive galaxies, and are instead powered by a central ionising source embedded in dense, absorbing gas.","lang":"eng"}]},{"scopus_import":"1","date_updated":"2025-09-30T14:44:53Z","PlanS_conform":"1","type":"journal_article","publication":"Foundations of Computational Mathematics","article_processing_charge":"Yes (via OA deal)","article_type":"original","language":[{"iso":"eng"}],"corr_author":"1","abstract":[{"lang":"eng","text":"We suggest a new algorithm to estimate representations of compact Lie groups from finite samples of their orbits. Different from other reported techniques, our method allows the retrieval of the precise representation type as a direct sum of irreducible representations. Moreover, the knowledge of the representation type permits the reconstruction of its orbit, which is useful for identifying the Lie group that generates the action, from a finite list of candidates. Our algorithm is general for any compact Lie group, but only instantiations for SO(2), T^d, SU(2), and SO(3) are considered. Theoretical guarantees of robustness in terms of Hausdorff and Wasserstein distances are derived. Our tools are drawn from geometric measure theory, computational geometry, and optimization on matrix manifolds. The algorithm is tested for synthetic data up to dimension 32, as well as real-life applications in image analysis, harmonic analysis, density estimation, equivariant neural networks, chemical conformational spaces, and classical mechanics systems, achieving very accurate results."}],"OA_type":"hybrid","day":"15","oa":1,"title":"LieDetect: Detection of representation orbits of compact Lie groups from point clouds","year":"2025","doi":"10.1007/s10208-025-09728-4","publication_status":"epub_ahead","main_file_link":[{"url":"https://doi.org/10.1007/s10208-025-09728-4","open_access":"1"}],"publication_identifier":{"issn":["1615-3375"],"eissn":["1615-3383"]},"_id":"20407","quality_controlled":"1","date_published":"2025-09-15T00:00:00Z","status":"public","month":"09","department":[{"_id":"UlWa"}],"date_created":"2025-09-28T22:01:27Z","citation":{"mla":"Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational Mathematics</i>, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s10208-025-09728-4\">10.1007/s10208-025-09728-4</a>.","short":"H. Ennes, R. Tinarrage, Foundations of Computational Mathematics (2025).","ista":"Ennes H, Tinarrage R. 2025. LieDetect: Detection of representation orbits of compact Lie groups from point clouds. Foundations of Computational Mathematics.","chicago":"Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational Mathematics</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s10208-025-09728-4\">https://doi.org/10.1007/s10208-025-09728-4</a>.","apa":"Ennes, H., &#38; Tinarrage, R. (2025). LieDetect: Detection of representation orbits of compact Lie groups from point clouds. <i>Foundations of Computational Mathematics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10208-025-09728-4\">https://doi.org/10.1007/s10208-025-09728-4</a>","ieee":"H. Ennes and R. Tinarrage, “LieDetect: Detection of representation orbits of compact Lie groups from point clouds,” <i>Foundations of Computational Mathematics</i>. Springer Nature, 2025.","ama":"Ennes H, Tinarrage R. LieDetect: Detection of representation orbits of compact Lie groups from point clouds. <i>Foundations of Computational Mathematics</i>. 2025. doi:<a href=\"https://doi.org/10.1007/s10208-025-09728-4\">10.1007/s10208-025-09728-4</a>"},"publisher":"Springer Nature","acknowledgement":"The original work behind this article was developed for HE’s master’s thesis, supervised by RT. We are mostly in debt to César Camacho, who was HE’s co-advisor, as well as the members of the thesis jury, Clément Maria, Eduardo Mendes, and Jameson Cahill, not only for agreeing to evaluate the original work but also for many valuable inputs. Finally, we are indebted to the anonymous reviewers for their important feedback and suggestions. Open access funding provided by Institute of Science and Technology (IST Austria).","oa_version":"Published Version","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_place":"publisher","isi":1,"author":[{"first_name":"Henrique","last_name":"Ennes","full_name":"Ennes, Henrique"},{"first_name":"Raphaël","last_name":"Tinarrage","full_name":"Tinarrage, Raphaël","id":"40ebcc9d-905f-11ef-bf0a-dc475da8a04e","orcid":"0000-0002-1404-1095"}],"external_id":{"isi":["001571197200001"],"arxiv":["2309.03086"]},"arxiv":1},{"scopus_import":"1","ddc":["510"],"type":"journal_article","publication":"Research in Number Theory","date_updated":"2025-10-13T12:30:40Z","PlanS_conform":"1","article_type":"original","article_processing_charge":"Yes (via OA deal)","corr_author":"1","abstract":[{"text":"For any d  2, we prove that there exists an integer n0(d) such that there exists an n × n\r\nmagic square of dth powers for all n  n0(d). In particular, we establish the existence of\r\nan n × n magic square of squares for all n  4, which settles a conjecture of\r\nVárilly-Alvarado. All previous approaches had been based on constructive methods and\r\nthe existence of n × n magic squares of dth powers had only been known for sparse\r\nvalues of n. We prove our result by the Hardy-Littlewood circle method, which in this\r\nsetting essentially reduces the problem to finding a sufficient number of disjoint linearly\r\nindependent subsets of the columns of the coefficient matrix of the equations defining\r\nmagic squares. We prove an optimal (up to a constant) lower bound for this quantity.","lang":"eng"}],"article_number":"91","language":[{"iso":"eng"}],"year":"2025","title":"On the existence of magic squares of powers","volume":11,"oa":1,"day":"23","OA_type":"hybrid","publication_status":"published","doi":"10.1007/s40993-025-00671-5","file_date_updated":"2025-10-13T11:28:49Z","_id":"20423","issue":"4","publication_identifier":{"eissn":["2363-9555"]},"intvolume":"        11","date_published":"2025-09-23T00:00:00Z","quality_controlled":"1","project":[{"grant_number":"P32428","_id":"26AEDAB2-B435-11E9-9278-68D0E5697425","name":"New frontiers of the Manin conjecture","call_identifier":"FWF"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"month":"09","status":"public","citation":{"chicago":"Rome, Nick, and Shuntaro Yamagishi. “On the Existence of Magic Squares of Powers.” <i>Research in Number Theory</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s40993-025-00671-5\">https://doi.org/10.1007/s40993-025-00671-5</a>.","ista":"Rome N, Yamagishi S. 2025. On the existence of magic squares of powers. Research in Number Theory. 11(4), 91.","short":"N. Rome, S. Yamagishi, Research in Number Theory 11 (2025).","mla":"Rome, Nick, and Shuntaro Yamagishi. “On the Existence of Magic Squares of Powers.” <i>Research in Number Theory</i>, vol. 11, no. 4, 91, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s40993-025-00671-5\">10.1007/s40993-025-00671-5</a>.","ieee":"N. Rome and S. Yamagishi, “On the existence of magic squares of powers,” <i>Research in Number Theory</i>, vol. 11, no. 4. Springer Nature, 2025.","ama":"Rome N, Yamagishi S. On the existence of magic squares of powers. <i>Research in Number Theory</i>. 2025;11(4). doi:<a href=\"https://doi.org/10.1007/s40993-025-00671-5\">10.1007/s40993-025-00671-5</a>","apa":"Rome, N., &#38; Yamagishi, S. (2025). On the existence of magic squares of powers. <i>Research in Number Theory</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s40993-025-00671-5\">https://doi.org/10.1007/s40993-025-00671-5</a>"},"publisher":"Springer Nature","department":[{"_id":"TiBr"}],"date_created":"2025-10-05T22:01:34Z","file":[{"file_id":"20463","date_updated":"2025-10-13T11:28:49Z","creator":"dernst","content_type":"application/pdf","date_created":"2025-10-13T11:28:49Z","relation":"main_file","access_level":"open_access","checksum":"d41fbdc0cfc1fbceb519eb49b20a3ec2","success":1,"file_size":428531,"file_name":"2025_ResearchNumberTheory_Rome.pdf"}],"has_accepted_license":"1","acknowledgement":"The authors are grateful to Tim Browning for his constant encouragement and enthusiasm, Jörg Brüdern for very helpful discussion regarding his paper [1] and Diyuan Wu for turning the proof of Theorem 2.4 in the original version into an algorithm and running the computation for us, for which the results are available in the appendix of the original version. They would also like to thank Christian Boyer for maintaining his website [4] which contains a comprehensive list of various magic squares discovered, Brady Haran and Tony Várilly-Alvarado for their public engagement activity of mathematics and magic squares of squares (A YouTube video “Magic Squares of Squares (are PROBABLY impossible)” of the Numberphile channel by Brady Haran, in which Tony Várilly-Alvarado appears as a guest speaker: https://www.youtube.com/watch?v=Kdsj84UdeYg.), and all the magic squares enthusiasts who have contributed to [4] which made this paper possible. Finally, the authors would like to thank the anonymous referees for their helpful comments, Daniel Flores for his work [11] which inspired them to optimise the proof of Theorem 2.4 and Trevor Wooley for very helpful discussion regarding recent developments in Waring’s problem and his comments on the original version of this paper.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria). NR was supported by FWF project ESP 441-NBL while SY by a FWF grant (DOI 10.55776/P32428).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","external_id":{"arxiv":["2406.09364"]},"arxiv":1,"author":[{"last_name":"Rome","first_name":"Nick","full_name":"Rome, Nick"},{"last_name":"Yamagishi","first_name":"Shuntaro","full_name":"Yamagishi, Shuntaro","id":"0c3fbc5c-f7a6-11ec-8d70-9485e75b416b"}],"OA_place":"publisher"},{"isi":1,"OA_place":"publisher","author":[{"last_name":"Sahu","first_name":"Preeti","full_name":"Sahu, Preeti","id":"55BA52EE-A185-11EA-88FD-18AD3DDC885E"},{"first_name":"Sara","last_name":"Monteiro-Ferreira","full_name":"Monteiro-Ferreira, Sara"},{"full_name":"Canato, Sara","first_name":"Sara","last_name":"Canato"},{"last_name":"Soares","first_name":"Raquel Maia","full_name":"Soares, Raquel Maia"},{"last_name":"Sánchez-Danés","first_name":"Adriana","full_name":"Sánchez-Danés, Adriana"},{"last_name":"Hannezo","first_name":"Edouard B","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B"}],"pmid":1,"DOAJ_listed":"1","external_id":{"pmid":["41006218"],"isi":["001582555200011"]},"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank Alois Schlögl, Paula Sanematsu, Susana Moreno Flores, Bernat Corominas-Murtra, Stefania Tavano, Gayathri Singharaju, and Hannezo group members for helpful discussions, the Bioimaging facility at ISTA, as well as Matthias Merkel and Lisa Manning for sharing the 3D Voronoi code. We also thank the Champalimaud animal facility, Anna Pezzarossa and the Champalimaud ABBE platform for the help with microscopy and image processing. This work was supported by EMBO (ALTF 522-2021), a Fundação para a Ciência e Tecnologia grant to A.S.D. (PTDC/MED-ONC/5553/2020), as well as the European Research Council (grant 851288 to EH). A.S.D., S.C., and R.M.S. are supported by QuantOCancer Project Horizon European Union’s Horizon 2020 program (grant agreement No 810653).","has_accepted_license":"1","file":[{"checksum":"d1656576883b23902545328e2d640234","success":1,"file_size":2816813,"file_name":"2025_NatureComm_Sahu.pdf","date_created":"2025-10-13T12:37:04Z","relation":"main_file","access_level":"open_access","creator":"dernst","content_type":"application/pdf","date_updated":"2025-10-13T12:37:04Z","file_id":"20464"}],"date_created":"2025-10-05T22:01:34Z","department":[{"_id":"EdHa"}],"publisher":"Springer Nature","citation":{"chicago":"Sahu, Preeti, Sara Monteiro-Ferreira, Sara Canato, Raquel Maia Soares, Adriana Sánchez-Danés, and Edouard B Hannezo. “Mechanical Control of Cell Fate Decisions in the Skin Epidermis.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-62882-9\">https://doi.org/10.1038/s41467-025-62882-9</a>.","ista":"Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo EB. 2025. Mechanical control of cell fate decisions in the skin epidermis. Nature Communications. 16, 8440.","mla":"Sahu, Preeti, et al. “Mechanical Control of Cell Fate Decisions in the Skin Epidermis.” <i>Nature Communications</i>, vol. 16, 8440, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-62882-9\">10.1038/s41467-025-62882-9</a>.","short":"P. Sahu, S. Monteiro-Ferreira, S. Canato, R.M. Soares, A. Sánchez-Danés, E.B. Hannezo, Nature Communications 16 (2025).","ieee":"P. Sahu, S. Monteiro-Ferreira, S. Canato, R. M. Soares, A. Sánchez-Danés, and E. B. Hannezo, “Mechanical control of cell fate decisions in the skin epidermis,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","apa":"Sahu, P., Monteiro-Ferreira, S., Canato, S., Soares, R. M., Sánchez-Danés, A., &#38; Hannezo, E. B. (2025). Mechanical control of cell fate decisions in the skin epidermis. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-62882-9\">https://doi.org/10.1038/s41467-025-62882-9</a>","ama":"Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo EB. Mechanical control of cell fate decisions in the skin epidermis. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-62882-9\">10.1038/s41467-025-62882-9</a>"},"status":"public","month":"09","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)"},"quality_controlled":"1","project":[{"_id":"628f3fb1-2b32-11ec-9570-83ce778803f7","name":"Biomechanics of stem cell fate determination","grant_number":"ALTF 522-2021"},{"name":"Design Principles of Branching Morphogenesis","_id":"05943252-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","grant_number":"851288"}],"date_published":"2025-09-26T00:00:00Z","intvolume":"        16","publication_identifier":{"eissn":["2041-1723"]},"_id":"20424","file_date_updated":"2025-10-13T12:37:04Z","ec_funded":1,"doi":"10.1038/s41467-025-62882-9","publication_status":"published","day":"26","OA_type":"gold","oa":1,"title":"Mechanical control of cell fate decisions in the skin epidermis","volume":16,"year":"2025","language":[{"iso":"eng"}],"article_number":"8440","acknowledged_ssus":[{"_id":"Bio"}],"abstract":[{"text":"Homeostasis relies on a precise balance of fate choices between renewal and differentiation. Although progress has been done to characterize the dynamics of single-cell fate choices, their underlying mechanistic basis often remains unclear. Concentrating on skin epidermis as a paradigm for multilayered tissues with complex fate choices, we develop a 3D vertex-based model with proliferation in the basal layer, showing that mechanical competition for space naturally gives rise to homeostasis and neutral drift dynamics that are seen experimentally. We then explore the effect of introducing mechanical heterogeneities between cellular subpopulations. We uncover that relatively small tension heterogeneities, reflected by distinct morphological changes in single-cell shapes, can be sufficient to heavily tilt cellular dynamics towards exponential growth. We thus derive a master relationship between cell shape and long-term clonal dynamics, which we validated during basal cell carcinoma initiation in mouse epidermis. Altogether, we propose a theoretical framework to link mechanical forces, quantitative cellular morphologies and cellular fate outcomes in complex tissues.","lang":"eng"}],"corr_author":"1","article_processing_charge":"Yes","article_type":"original","date_updated":"2025-12-01T12:54:59Z","publication":"Nature Communications","type":"journal_article","ddc":["570"],"scopus_import":"1"},{"type":"journal_article","publication":"The Astrophysical Journal Letters","date_updated":"2026-02-16T12:44:42Z","PlanS_conform":"1","scopus_import":"1","ddc":["520"],"article_type":"original","article_processing_charge":"Yes","year":"2025","title":"The light echo of a high-redshift quasar mapped with Lyα tomography","volume":991,"oa":1,"OA_type":"gold","day":"25","abstract":[{"text":"Ultraviolet (UV) radiation from accreting black holes ionizes the intergalactic gas around early quasars, carving out highly ionized bubbles in their surroundings. Any changes in a quasar’s luminosity are therefore predicted to produce outward-propagating ionization gradients, affecting the Lyα absorption opacity near the quasar’s systemic redshift. This “proximity effect” is well-documented in rest-UV quasar spectra but only provides a one-dimensional probe along our line of sight. Here we present deep spectroscopic observations with the James Webb Space Telescope (JWST) of galaxies in the background of a superluminous quasar at zQSO ≈ 6.3, which reveal the quasar’s “light echo” with Lyα tomography in the transverse direction. This transverse proximity effect is detected for the first time toward multiple galaxy sightlines, allowing us to map the extent and geometry of the quasar’s ionization cone. We obtain constraints on the orientation and inclination of the cone, as well as an upper limit on the obscured solid angle fraction of fobsc < 91%. Additionally, we find a timescale of the quasar’s UV radiation of tqso = 10^5.6+0.1-0.3 yr, which is significantly shorter than would be required to build up the central supermassive black hole (SMBH) with conventional growth models, but is consistent with independent measurements of the quasars’ duty cycle. Our inferred obscured fraction disfavors a scenario where short quasar lifetimes can be explained exclusively by geometric obscuration, and instead supports the idea that radiatively inefficient accretion or growth in initially heavily enshrouded cocoons plays a pivotal role in early SMBH growth. Our results pave the way for novel studies of quasars’ ionizing geometries and radiative histories at early cosmic times.","lang":"eng"}],"article_number":"L40","language":[{"iso":"eng"}],"file_date_updated":"2025-10-13T09:25:12Z","publication_status":"published","doi":"10.3847/2041-8213/ae057a","date_published":"2025-09-25T00:00:00Z","project":[{"name":"Young galaxies as tracers and agents of cosmic reionization","_id":"bd9b2118-d553-11ed-ba76-db24564edfea","grant_number":"101076224"}],"quality_controlled":"1","_id":"20425","intvolume":"       991","publication_identifier":{"eissn":["2041-8213"],"issn":["2041-8205"]},"issue":"2","citation":{"short":"A.C. Eilers, M. Yue, J.J. Matthee, J.F. Hennawi, F.B. Davies, R.A. Simcoe, R. Teague, R. Bordoloi, G. Brammer, Y. Kang, D. Kashino, R. Mackenzie, R.P. Naidu, B. Navarrete, The Astrophysical Journal Letters 991 (2025).","mla":"Eilers, Anna Christina, et al. “The Light Echo of a High-Redshift Quasar Mapped with Lyα Tomography.” <i>The Astrophysical Journal Letters</i>, vol. 991, no. 2, L40, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.3847/2041-8213/ae057a\">10.3847/2041-8213/ae057a</a>.","ista":"Eilers AC, Yue M, Matthee JJ, Hennawi JF, Davies FB, Simcoe RA, Teague R, Bordoloi R, Brammer G, Kang Y, Kashino D, Mackenzie R, Naidu RP, Navarrete B. 2025. The light echo of a high-redshift quasar mapped with Lyα tomography. The Astrophysical Journal Letters. 991(2), L40.","chicago":"Eilers, Anna Christina, Minghao Yue, Jorryt J Matthee, Joseph F. Hennawi, Frederick B. Davies, Robert A. Simcoe, Richard Teague, et al. “The Light Echo of a High-Redshift Quasar Mapped with Lyα Tomography.” <i>The Astrophysical Journal Letters</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.3847/2041-8213/ae057a\">https://doi.org/10.3847/2041-8213/ae057a</a>.","ieee":"A. C. Eilers <i>et al.</i>, “The light echo of a high-redshift quasar mapped with Lyα tomography,” <i>The Astrophysical Journal Letters</i>, vol. 991, no. 2. IOP Publishing, 2025.","apa":"Eilers, A. C., Yue, M., Matthee, J. J., Hennawi, J. F., Davies, F. B., Simcoe, R. A., … Navarrete, B. (2025). The light echo of a high-redshift quasar mapped with Lyα tomography. <i>The Astrophysical Journal Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.3847/2041-8213/ae057a\">https://doi.org/10.3847/2041-8213/ae057a</a>","ama":"Eilers AC, Yue M, Matthee JJ, et al. The light echo of a high-redshift quasar mapped with Lyα tomography. <i>The Astrophysical Journal Letters</i>. 2025;991(2). doi:<a href=\"https://doi.org/10.3847/2041-8213/ae057a\">10.3847/2041-8213/ae057a</a>"},"publisher":"IOP Publishing","date_created":"2025-10-05T22:01:35Z","department":[{"_id":"JoMa"},{"_id":"GradSch"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"month":"09","status":"public","file":[{"creator":"dernst","content_type":"application/pdf","date_updated":"2025-10-13T09:25:12Z","file_id":"20461","checksum":"3cb8099b9a915755164e5675b33f8a03","file_size":23585591,"success":1,"file_name":"2025_AstrophysicalJour_Eilers.pdf","date_created":"2025-10-13T09:25:12Z","relation":"main_file","access_level":"open_access"}],"has_accepted_license":"1","acknowledgement":"This work is based on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programs #1243 and #4713.\r\n\r\nAll of the data presented in this Letter were obtained from the Mikulski Archive for Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations analyzed can be accessed via doi:10.17909/w7hm-qb39.\r\nJ.M. is supported by the European Union (ERC, AGENTS, 101076224).","DOAJ_listed":"1","arxiv":1,"external_id":{"isi":["001581023000001"],"arxiv":["2509.05417"]},"author":[{"last_name":"Eilers","first_name":"Anna Christina","full_name":"Eilers, Anna Christina"},{"full_name":"Yue, Minghao","first_name":"Minghao","last_name":"Yue"},{"last_name":"Matthee","first_name":"Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","full_name":"Matthee, Jorryt J","orcid":"0000-0003-2871-127X"},{"full_name":"Hennawi, Joseph F.","first_name":"Joseph F.","last_name":"Hennawi"},{"first_name":"Frederick B.","last_name":"Davies","full_name":"Davies, Frederick B."},{"first_name":"Robert A.","last_name":"Simcoe","full_name":"Simcoe, Robert A."},{"full_name":"Teague, Richard","first_name":"Richard","last_name":"Teague"},{"first_name":"Rongmon","last_name":"Bordoloi","full_name":"Bordoloi, Rongmon"},{"last_name":"Brammer","first_name":"Gabriel","full_name":"Brammer, Gabriel"},{"first_name":"Yi","last_name":"Kang","full_name":"Kang, Yi"},{"full_name":"Kashino, Daichi","first_name":"Daichi","last_name":"Kashino"},{"full_name":"Mackenzie, Ruari","first_name":"Ruari","last_name":"Mackenzie"},{"last_name":"Naidu","first_name":"Rohan P.","full_name":"Naidu, Rohan P."},{"id":"aa14a535-50c9-11ef-b52e-e0c373d10148","full_name":"Navarrete, Benjamín","last_name":"Navarrete","first_name":"Benjamín"}],"OA_place":"publisher","isi":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version"},{"date_created":"2025-10-05T22:01:35Z","department":[{"_id":"MaIb"}],"publisher":"American Chemical Society","citation":{"ista":"Meng W, Xu L, Lu S, Li M, Li M, Zhang Y, Wang Q, Wang WJ, Huo S, Bañares MA, Martin-Gonzalez M, Ibáñez M, Cabot A, Hong M, Liu Y, Lim KH. 2025. Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. ACS Nano. 19(38), 34395–34407.","short":"W. Meng, L. Xu, S. Lu, M. Li, M. Li, Y. Zhang, Q. Wang, W.J. Wang, S. Huo, M.A. Bañares, M. Martin-Gonzalez, M. Ibáñez, A. Cabot, M. Hong, Y. Liu, K.H. Lim, ACS Nano 19 (2025) 34395–34407.","mla":"Meng, Weite, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>, vol. 19, no. 38, American Chemical Society, 2025, pp. 34395–407, doi:<a href=\"https://doi.org/10.1021/acsnano.5c12627\">10.1021/acsnano.5c12627</a>.","chicago":"Meng, Weite, Lixiang Xu, Shaoqing Lu, Mingquan Li, Mengyao Li, Yu Zhang, Qingyue Wang, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsnano.5c12627\">https://doi.org/10.1021/acsnano.5c12627</a>.","ama":"Meng W, Xu L, Lu S, et al. Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. <i>ACS Nano</i>. 2025;19(38):34395-34407. doi:<a href=\"https://doi.org/10.1021/acsnano.5c12627\">10.1021/acsnano.5c12627</a>","ieee":"W. Meng <i>et al.</i>, “Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance,” <i>ACS Nano</i>, vol. 19, no. 38. American Chemical Society, pp. 34395–34407, 2025.","apa":"Meng, W., Xu, L., Lu, S., Li, M., Li, M., Zhang, Y., … Lim, K. H. (2025). Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.5c12627\">https://doi.org/10.1021/acsnano.5c12627</a>"},"status":"public","month":"09","page":"34395-34407","quality_controlled":"1","date_published":"2025-09-30T00:00:00Z","publication_identifier":{"eissn":["1936-086X"],"issn":["1936-0851"]},"issue":"38","intvolume":"        19","_id":"20426","isi":1,"pmid":1,"author":[{"full_name":"Meng, Weite","last_name":"Meng","first_name":"Weite"},{"first_name":"Lixiang","last_name":"Xu","full_name":"Xu, Lixiang"},{"full_name":"Lu, Shaoqing","last_name":"Lu","first_name":"Shaoqing"},{"full_name":"Li, Mingquan","first_name":"Mingquan","last_name":"Li"},{"last_name":"Li","first_name":"Mengyao","full_name":"Li, Mengyao"},{"full_name":"Zhang, Yu","last_name":"Zhang","first_name":"Yu"},{"full_name":"Wang, Qingyue","first_name":"Qingyue","last_name":"Wang"},{"last_name":"Wang","first_name":"Wen Jun","full_name":"Wang, Wen Jun"},{"first_name":"Siqi","last_name":"Huo","full_name":"Huo, Siqi"},{"last_name":"Bañares","first_name":"Miguel A.","full_name":"Bañares, Miguel A."},{"full_name":"Martin-Gonzalez, Marisol","first_name":"Marisol","last_name":"Martin-Gonzalez"},{"first_name":"Maria","last_name":"Ibáñez","orcid":"0000-0001-5013-2843","id":"43C61214-F248-11E8-B48F-1D18A9856A87","full_name":"Ibáñez, Maria"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"},{"last_name":"Hong","first_name":"Min","full_name":"Hong, Min"},{"last_name":"Liu","first_name":"Yu","id":"2A70014E-F248-11E8-B48F-1D18A9856A87","full_name":"Liu, Yu","orcid":"0000-0001-7313-6740"},{"last_name":"Lim","first_name":"Khak Ho","full_name":"Lim, Khak Ho"}],"external_id":{"isi":["001575398100001"],"pmid":["40974325"]},"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"Y.L. acknowledges funding from the National Natural Science Foundation of China (NSFC) (Grant No. 22209034), the Innovation and Entrepreneurship Project of Overseas Returnees in Anhui Province (Grant No. 2022LCX002), and the Fundamental Research Funds for the Central Universities (JZ2024HGTB0239). K.H.L. acknowledges financial support from the National Natural Science Foundation of China (NSFC) (Grant No. 22208293) and the National Foreign Expert Project (Y20240175). Y.Z. acknowledges funding from the NSFC (Grant No. 52502313) and Wenzhou Basic Scientific Research Project (Grant No. G20240034). Q.W. acknowledges the financial support from the NSFC (Grant No. 22208292) and the “Pioneer” and “Leading Goose” R&D Program of Zhejiang (2025C04021). K.H.L. and Q.W. also acknowledge the Research Funds of the Institute of Zhejiang University-Quzhou (Nos. IZQ2022RCZX101, IZQ2021RCZX003, and IZQ2021RCZX002). M.H. acknowledges the funding from the Australian Research Council and the iLAuNCH Trailblazer, Department of Education, Australia. M.H. acknowledges the computational support from the National Computational Infrastructure (NCI), Australia and Pawsey Supercomputing Centre, Australia. The author also thanks Dr. Lijian Huang and Mr. Mincheng Yu at the Institute of Zhejiang University for the swift technical assistance during XPS characterization and quantification.","article_processing_charge":"No","article_type":"original","date_updated":"2025-12-01T12:50:24Z","publication":"ACS Nano","type":"journal_article","scopus_import":"1","doi":"10.1021/acsnano.5c12627","publication_status":"published","day":"30","OA_type":"closed access","title":"Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials toward high thermoelectric performance","volume":19,"year":"2025","language":[{"iso":"eng"}],"abstract":[{"text":"SnTe has attracted significant research interest as a lead-free alternative to PbTe; however, its intrinsically high hole concentration results in an undesirably low Seebeck coefficient and elevated electronic thermal conductivity, thus significantly limiting its thermoelectric (TE) performance. Herein, we present a cost-effective, binary thiol-amine-mediated colloidal synthesis method to synthesize Bi-doped SnTe nanoparticles, eliminating the use of tri-n-octylphosphine-based precursors. The introduction of an electron-rich Bi dopant reduces the hole concentration and increases the Seebeck coefficient. Furthermore, post-synthetic surface treatment with chalcogenidocadmate complexes promotes atomic interdiffusion during annealing and consolidation, leading to compositional redistribution and modulation of the electronic band structure. Density functional theory (DFT) calculations reveal that co-modification via Bi doping and CdSe-derived chalcogen incorporation reduces the energy offset at the valence band maxima from 0.30 eV to 0.10 eV, thereby enhancing valence band degeneracy. The synergistic structural and electronic band structure modulations produce an SnTe-based material with a record high power factor of 2.1 mW m–1 K–2 at 900 K, a maximum TE figure of merit (zT) of 1.2, and a promising theoretical conversion efficiency of 8.3%. This study reports a versatile and scalable colloidal synthesis strategy that integrates hierarchical structural modulation with electronic band engineering, offering a synergistic route to significantly enhance the TE performance.","lang":"eng"}]},{"author":[{"id":"922e68bb-1727-11ee-857c-966e8cc1b6c3","full_name":"Li, Ziqiang","first_name":"Ziqiang","last_name":"Li"},{"orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K","last_name":"Sixt","first_name":"Michael K"}],"pmid":1,"external_id":{"pmid":["40987270"],"isi":["001592664700001"]},"isi":1,"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2025-09-22T00:00:00Z","quality_controlled":"1","issue":"18","intvolume":"        35","publication_identifier":{"eissn":["1879-0445"]},"_id":"20427","publisher":"Elsevier","citation":{"ista":"LI Z, Sixt MK. 2025. Cell migration: How animal cells run and tumble. Current Biology. 35(18), R890–R892.","short":"Z. LI, M.K. Sixt, Current Biology 35 (2025) R890–R892.","mla":"LI, ZIQIANG, and Michael K. Sixt. “Cell Migration: How Animal Cells Run and Tumble.” <i>Current Biology</i>, vol. 35, no. 18, Elsevier, 2025, pp. R890–92, doi:<a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">10.1016/j.cub.2025.08.016</a>.","chicago":"LI, ZIQIANG, and Michael K Sixt. “Cell Migration: How Animal Cells Run and Tumble.” <i>Current Biology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">https://doi.org/10.1016/j.cub.2025.08.016</a>.","ama":"LI Z, Sixt MK. Cell migration: How animal cells run and tumble. <i>Current Biology</i>. 2025;35(18):R890-R892. doi:<a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">10.1016/j.cub.2025.08.016</a>","apa":"LI, Z., &#38; Sixt, M. K. (2025). Cell migration: How animal cells run and tumble. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2025.08.016\">https://doi.org/10.1016/j.cub.2025.08.016</a>","ieee":"Z. LI and M. K. Sixt, “Cell migration: How animal cells run and tumble,” <i>Current Biology</i>, vol. 35, no. 18. Elsevier, pp. R890–R892, 2025."},"department":[{"_id":"MiSi"}],"date_created":"2025-10-05T22:01:35Z","page":"R890-R892","status":"public","month":"09","title":"Cell migration: How animal cells run and tumble","volume":35,"year":"2025","day":"22","OA_type":"closed access","abstract":[{"lang":"eng","text":"Animal cells migrating up chemotactic gradients often show speed oscillations. A new study describes a molecular circuit that switches zebrafish germ cells between phases of straight runs, tumbling and directional reorientation."}],"corr_author":"1","language":[{"iso":"eng"}],"publication_status":"published","doi":"10.1016/j.cub.2025.08.016","date_updated":"2025-12-01T12:54:02Z","publication":"Current Biology","type":"journal_article","scopus_import":"1","article_type":"letter_note","article_processing_charge":"No"},{"page":"1645-1647","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"status":"public","month":"08","publisher":"Beilstein Institut","citation":{"ieee":"T. Noël and B. Pieber, “Photocatalysis and photochemistry in organic synthesis,” <i>Beilstein Journal of Organic Chemistry</i>, vol. 21. Beilstein Institut, pp. 1645–1647, 2025.","apa":"Noël, T., &#38; Pieber, B. (2025). Photocatalysis and photochemistry in organic synthesis. <i>Beilstein Journal of Organic Chemistry</i>. Beilstein Institut. <a href=\"https://doi.org/10.3762/bjoc.21.128\">https://doi.org/10.3762/bjoc.21.128</a>","ama":"Noël T, Pieber B. Photocatalysis and photochemistry in organic synthesis. <i>Beilstein Journal of Organic Chemistry</i>. 2025;21:1645-1647. doi:<a href=\"https://doi.org/10.3762/bjoc.21.128\">10.3762/bjoc.21.128</a>","short":"T. Noël, B. Pieber, Beilstein Journal of Organic Chemistry 21 (2025) 1645–1647.","mla":"Noël, Timothy, and Bartholomäus Pieber. “Photocatalysis and Photochemistry in Organic Synthesis.” <i>Beilstein Journal of Organic Chemistry</i>, vol. 21, Beilstein Institut, 2025, pp. 1645–47, doi:<a href=\"https://doi.org/10.3762/bjoc.21.128\">10.3762/bjoc.21.128</a>.","ista":"Noël T, Pieber B. 2025. Photocatalysis and photochemistry in organic synthesis. Beilstein Journal of Organic Chemistry. 21, 1645–1647.","chicago":"Noël, Timothy, and Bartholomäus Pieber. “Photocatalysis and Photochemistry in Organic Synthesis.” <i>Beilstein Journal of Organic Chemistry</i>. Beilstein Institut, 2025. <a href=\"https://doi.org/10.3762/bjoc.21.128\">https://doi.org/10.3762/bjoc.21.128</a>."},"date_created":"2025-10-05T22:01:35Z","department":[{"_id":"BaPi"}],"intvolume":"        21","publication_identifier":{"eissn":["1860-5397"]},"_id":"20428","date_published":"2025-08-18T00:00:00Z","quality_controlled":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"first_name":"Timothy","last_name":"Noël","full_name":"Noël, Timothy"},{"first_name":"Bartholomäus","last_name":"Pieber","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus","orcid":"0000-0001-8689-388X"}],"pmid":1,"external_id":{"pmid":["40927207"]},"DOAJ_listed":"1","OA_place":"publisher","acknowledgement":"The Graphical Abstract was created with the AI tool https://wordart.com. This content is not subject to CC BY 4.0.","has_accepted_license":"1","file":[{"date_updated":"2025-10-13T11:18:02Z","file_id":"20462","content_type":"application/pdf","creator":"dernst","access_level":"open_access","relation":"main_file","date_created":"2025-10-13T11:18:02Z","file_name":"2025_BeilsteinJourOrgChemistry_Noel.pdf","success":1,"file_size":117869,"checksum":"45a4ac237e55fdcad168aeb5bd5be61d"}],"article_type":"editorial","article_processing_charge":"No","ddc":["540"],"scopus_import":"1","date_updated":"2025-10-13T11:21:01Z","PlanS_conform":"1","type":"journal_article","publication":"Beilstein Journal of Organic Chemistry","publication_status":"published","doi":"10.3762/bjoc.21.128","file_date_updated":"2025-10-13T11:18:02Z","corr_author":"1","language":[{"iso":"eng"}],"volume":21,"title":"Photocatalysis and photochemistry in organic synthesis","year":"2025","OA_type":"diamond","day":"18","oa":1},{"publication_identifier":{"issn":["1385-0237"],"eissn":["1573-5052"]},"intvolume":"       226","_id":"20429","quality_controlled":"1","date_published":"2025-12-01T00:00:00Z","status":"public","month":"12","page":"1301-1313","date_created":"2025-10-05T22:01:36Z","department":[{"_id":"NiBa"}],"citation":{"chicago":"Bustamante, Gimena Noemí, Miriam Elisabet Arena, Luciano Selzer, Matthew Ruggirello, Paula Rodríguez, Samuele Pedrazzani, Jose Antonio Navarro-Cano, and Rosina Matilde Soler Schaller. “Biotic Interactions between Trees and Colonizing Shrubs: Implications for Active Restoration in Southern Patagonian Forests.” <i>Plant Ecology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s11258-025-01568-0\">https://doi.org/10.1007/s11258-025-01568-0</a>.","ista":"Bustamante GN, Arena ME, Selzer L, Ruggirello M, Rodríguez P, Pedrazzani S, Navarro-Cano JA, Soler Schaller RM. 2025. Biotic interactions between trees and colonizing shrubs: Implications for active restoration in southern Patagonian forests. Plant Ecology. 226, 1301–1313.","mla":"Bustamante, Gimena Noemí, et al. “Biotic Interactions between Trees and Colonizing Shrubs: Implications for Active Restoration in Southern Patagonian Forests.” <i>Plant Ecology</i>, vol. 226, Springer Nature, 2025, pp. 1301–13, doi:<a href=\"https://doi.org/10.1007/s11258-025-01568-0\">10.1007/s11258-025-01568-0</a>.","short":"G.N. Bustamante, M.E. Arena, L. Selzer, M. Ruggirello, P. Rodríguez, S. Pedrazzani, J.A. Navarro-Cano, R.M. Soler Schaller, Plant Ecology 226 (2025) 1301–1313.","ieee":"G. N. Bustamante <i>et al.</i>, “Biotic interactions between trees and colonizing shrubs: Implications for active restoration in southern Patagonian forests,” <i>Plant Ecology</i>, vol. 226. Springer Nature, pp. 1301–1313, 2025.","apa":"Bustamante, G. N., Arena, M. E., Selzer, L., Ruggirello, M., Rodríguez, P., Pedrazzani, S., … Soler Schaller, R. M. (2025). Biotic interactions between trees and colonizing shrubs: Implications for active restoration in southern Patagonian forests. <i>Plant Ecology</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11258-025-01568-0\">https://doi.org/10.1007/s11258-025-01568-0</a>","ama":"Bustamante GN, Arena ME, Selzer L, et al. Biotic interactions between trees and colonizing shrubs: Implications for active restoration in southern Patagonian forests. <i>Plant Ecology</i>. 2025;226:1301-1313. doi:<a href=\"https://doi.org/10.1007/s11258-025-01568-0\">10.1007/s11258-025-01568-0</a>"},"publisher":"Springer Nature","oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"author":[{"first_name":"Gimena Noemí","last_name":"Bustamante","full_name":"Bustamante, Gimena Noemí"},{"full_name":"Arena, Miriam Elisabet","first_name":"Miriam Elisabet","last_name":"Arena"},{"full_name":"Selzer, Luciano","last_name":"Selzer","first_name":"Luciano"},{"last_name":"Ruggirello","first_name":"Matthew","full_name":"Ruggirello, Matthew"},{"first_name":"Paula","last_name":"Rodríguez","full_name":"Rodríguez, Paula"},{"last_name":"Pedrazzani","first_name":"Samuele","full_name":"Pedrazzani, Samuele"},{"full_name":"Navarro-Cano, Jose Antonio","first_name":"Jose Antonio","last_name":"Navarro-Cano"},{"id":"9e668447-8c32-11ed-b0c7-8dc2d7b80803","full_name":"Soler Schaller, Rosina Matilde","last_name":"Soler Schaller","first_name":"Rosina Matilde"}],"external_id":{"isi":["001581599800001"]},"scopus_import":"1","date_updated":"2026-01-05T13:23:57Z","publication":"Plant Ecology","type":"journal_article","article_processing_charge":"No","article_type":"original","language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Plant–plant interactions are key to understanding ecosystem services and shaping restoration strategies, as they can produce either negative or positive effects, determining species establishment and growth. Recognizing these interactions during early-life stages provides valuable insights for restoration in human-disturbed areas. One promising approach is nucleation planting, which establishes small clusters of native species in strategically selected sites, being particularly useful in sites with large herbivores. In southern Patagonia, livestock production has historically been the main economic activity, severely impacting extensive areas of Nothofagus antarctica forest through grazing and intentional burning to increase forage. In this context, nucleation planting with Berberis microphylla, a non-palatable shrub, could foster forest recovery in degraded sites. To evaluate this, we conducted an experiment testing the response of trees to varying shrub number, while also assessing intraspecific effects in both species. We measured survival, biomass, and functional traits. Results showed that the combination of four shrubs surrounding a single tree maintained tree survival at levels comparable to trees growing alone, while seedlings exhibited conspecific negative plant number dependence. Additionally, B. microphylla increased its below- to above-ground biomass ratio under higher plant number, indicating resource reallocation and niche differentiation through spatial separation of root systems."}],"OA_type":"closed access","day":"01","title":"Biotic interactions between trees and colonizing shrubs: Implications for active restoration in southern Patagonian forests","volume":226,"year":"2025","doi":"10.1007/s11258-025-01568-0","publication_status":"published"},{"publication":"Nature","type":"journal_article","date_updated":"2026-01-05T13:18:17Z","PlanS_conform":"1","scopus_import":"1","ddc":["570"],"article_processing_charge":"Yes (in subscription journal)","article_type":"original","oa":1,"OA_type":"hybrid","day":"13","year":"2025","title":"Design of facilitated dissociation enables timing of cytokine signalling","volume":647,"language":[{"iso":"eng"}],"corr_author":"1","abstract":[{"lang":"eng","text":"Protein design has focused on the design of ground states, ensuring that they are sufficiently low energy to be highly populated1. Designing the kinetics and dynamics of a system requires, in addition, the design of excited states that are traversed in transitions from one low-lying state to another2,3. This is a challenging task because such states must be sufficiently strained to be poorly populated, but not so strained that they are not populated at all, and because protein design methods have focused on generating near-ideal structures4,5,6,7. Here we describe a general approach for designing systems that use an induced-fit power stroke8 to generate a structurally frustrated9 and strained excited state, allosterically driving protein complex dissociation. X-ray crystallography, double electron–electron resonance spectroscopy and kinetic binding measurements show that incorporating excited states enables the design of effector-induced increases in dissociation rates as high as 5,700-fold. We highlight the power of this approach by designing rapid biosensors, kinetically controlled circuits and cytokine mimics that can be dissociated from their receptors within seconds, enabling dissection of the temporal dynamics of interleukin-2 signalling."}],"file_date_updated":"2026-01-05T13:17:47Z","doi":"10.1038/s41586-025-09549-z","publication_status":"published","quality_controlled":"1","date_published":"2025-11-13T00:00:00Z","_id":"20430","publication_identifier":{"eissn":["1476-4687"],"issn":["0028-0836"]},"intvolume":"       647","date_created":"2025-10-05T22:01:36Z","department":[{"_id":"FlPr"}],"publisher":"Springer Nature","citation":{"ieee":"A. J. Broerman <i>et al.</i>, “Design of facilitated dissociation enables timing of cytokine signalling,” <i>Nature</i>, vol. 647. Springer Nature, pp. 528–535, 2025.","ama":"Broerman AJ, Pollmann C, Zhao Y, et al. Design of facilitated dissociation enables timing of cytokine signalling. <i>Nature</i>. 2025;647:528-535. doi:<a href=\"https://doi.org/10.1038/s41586-025-09549-z\">10.1038/s41586-025-09549-z</a>","apa":"Broerman, A. J., Pollmann, C., Zhao, Y., Lichtenstein, M. A., Jackson, M. D., Tessmer, M. H., … Baker, D. (2025). Design of facilitated dissociation enables timing of cytokine signalling. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-025-09549-z\">https://doi.org/10.1038/s41586-025-09549-z</a>","chicago":"Broerman, Adam J., Christoph Pollmann, Yang Zhao, Mauriz A. Lichtenstein, Mark D. Jackson, Maxx H. Tessmer, Won Hee Ryu, et al. “Design of Facilitated Dissociation Enables Timing of Cytokine Signalling.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-025-09549-z\">https://doi.org/10.1038/s41586-025-09549-z</a>.","ista":"Broerman AJ, Pollmann C, Zhao Y, Lichtenstein MA, Jackson MD, Tessmer MH, Ryu WH, Ogishi M, Abedi MH, Sahtoe DD, Allen A, Kang A, De La Cruz J, Brackenbrough E, Sankaran B, Bera AK, Zuckerman DM, Stoll S, Garcia KC, Praetorius FM, Piehler J, Baker D. 2025. Design of facilitated dissociation enables timing of cytokine signalling. Nature. 647, 528–535.","short":"A.J. Broerman, C. Pollmann, Y. Zhao, M.A. Lichtenstein, M.D. Jackson, M.H. Tessmer, W.H. Ryu, M. Ogishi, M.H. Abedi, D.D. Sahtoe, A. Allen, A. Kang, J. De La Cruz, E. Brackenbrough, B. Sankaran, A.K. Bera, D.M. Zuckerman, S. Stoll, K.C. Garcia, F.M. Praetorius, J. Piehler, D. Baker, Nature 647 (2025) 528–535.","mla":"Broerman, Adam J., et al. “Design of Facilitated Dissociation Enables Timing of Cytokine Signalling.” <i>Nature</i>, vol. 647, Springer Nature, 2025, pp. 528–35, doi:<a href=\"https://doi.org/10.1038/s41586-025-09549-z\">10.1038/s41586-025-09549-z</a>."},"month":"11","status":"public","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"page":"528-535","file":[{"date_updated":"2026-01-05T13:17:47Z","file_id":"20951","content_type":"application/pdf","creator":"dernst","access_level":"open_access","relation":"main_file","date_created":"2026-01-05T13:17:47Z","file_name":"2025_Nature_Broerman.pdf","file_size":22099921,"success":1,"checksum":"b4ec44134e2eb320a724dc29158dfda2"}],"acknowledgement":"We thank P. J. Y. Leung, K. L. Shelley, A. Pillai, C. Demakis, M. Exposit, K. Thompson, C. Savvides, R. J. Ragotte, G. Ahn and M. Glögl for discussions and technical support; K. VanWormer and L. Goldschmidt for technical support; S. R. Gerben and A. Murray for protein production support; and X. Li, M. Lamb, Z. Taylor and V. Adebomi for LC–MS support. This work was supported by the Audacious Project at the Institute for Protein Design (A.J.B., A.K., J.D.L.C., E.B. and A.K.B.); by a gift from Microsoft (A.J.B.); by the Nordstrom Barrier Institute for Protein Design Directors Fund (M.H.A. and F.P.); by Bill and Melinda Gates Foundation OPP1156262 (A.K. and J.D.L.C.); by the Open Philanthropy Project Improving Protein Design Fund (E.B. and A.K.B.); by the National Institutes of Health (NIH) National Institute of Allergy and Infectious Disease grant R0AI160052 (A.K.B.); by CRI Irvington Postdoctoral Fellowship 315511 (Y.Z.); by National Cancer Institute K00 award 4K00CA274708 (M.O.); by National Science Foundation grant MCB 2119837 and NIH grant GM115805 (W.H.R. and D.M.Z.); by NIH grant GM151956 (S.S.); by NIH AI-51321 (K.C.G.); by the DFG grants PI 405/15 and SFB 1557 (C.P. and J.P.); and by the Howard Hughes Medical Institute (A.K.B., K.C.G. and D.B.). The EPR spectrometer used for the DEER experiments was in part supported by NIH grant S10OD021557. This research used resources (FMX/AMX) of the National Synchrotron Light Source II, a US Department of Energy (DoE) Office of Science User Facility operated for the DOE Office of Science by Brookhaven National Laboratory under contract DE-SC0012704. The Center for BioMolecular Structure (CBMS) is supported mainly by the NIH National Institute of General Medical Sciences (NIGMS) through a Center Core P30 Grant (P30GM133893), and by the DoE Office of Biological and Environmental Research (KP1607011). This work is based on research performed at the Northeastern Collaborative Access Team beamlines, which are funded by the NIGMS (P30 GM124165). The research used resources of the Advanced Photon Source, a US DoE Office of Science User Facility operated for the DoE Office of Science by Argonne National Laboratory under contract DE-AC02-06CH11357. The Berkeley Center for Structural Biology is supported by the NIH, NIGMS and the Howard Hughes Medical Institute. The Advanced Light Source is supported by the Director, Office of Science, Office of Basic Energy Sciences and US DoE (DE-AC02-05CH11231).","has_accepted_license":"1","OA_place":"publisher","isi":1,"external_id":{"isi":["001577755600001"],"pmid":["40993395"]},"pmid":1,"author":[{"full_name":"Broerman, Adam J.","last_name":"Broerman","first_name":"Adam J."},{"first_name":"Christoph","last_name":"Pollmann","full_name":"Pollmann, Christoph"},{"full_name":"Zhao, Yang","first_name":"Yang","last_name":"Zhao"},{"first_name":"Mauriz A.","last_name":"Lichtenstein","full_name":"Lichtenstein, Mauriz A."},{"last_name":"Jackson","first_name":"Mark D.","full_name":"Jackson, Mark D."},{"first_name":"Maxx H.","last_name":"Tessmer","full_name":"Tessmer, Maxx H."},{"first_name":"Won Hee","last_name":"Ryu","full_name":"Ryu, Won Hee"},{"full_name":"Ogishi, Masato","last_name":"Ogishi","first_name":"Masato"},{"full_name":"Abedi, Mohamad H.","last_name":"Abedi","first_name":"Mohamad H."},{"first_name":"Danny D.","last_name":"Sahtoe","full_name":"Sahtoe, Danny D."},{"last_name":"Allen","first_name":"Aza","full_name":"Allen, Aza"},{"full_name":"Kang, Alex","last_name":"Kang","first_name":"Alex"},{"full_name":"De La Cruz, Joshmyn","last_name":"De La Cruz","first_name":"Joshmyn"},{"last_name":"Brackenbrough","first_name":"Evans","full_name":"Brackenbrough, Evans"},{"full_name":"Sankaran, Banumathi","last_name":"Sankaran","first_name":"Banumathi"},{"last_name":"Bera","first_name":"Asim K.","full_name":"Bera, Asim K."},{"full_name":"Zuckerman, Daniel M.","first_name":"Daniel M.","last_name":"Zuckerman"},{"full_name":"Stoll, Stefan","last_name":"Stoll","first_name":"Stefan"},{"last_name":"Garcia","first_name":"K. Christopher","full_name":"Garcia, K. Christopher"},{"first_name":"Florian M","last_name":"Praetorius","id":"dfec9381-4341-11ee-8fd8-faa02bba7d62","full_name":"Praetorius, Florian M","orcid":"0000-0002-0806-8101"},{"full_name":"Piehler, Jacob","first_name":"Jacob","last_name":"Piehler"},{"last_name":"Baker","first_name":"David","full_name":"Baker, David"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version"},{"publisher":"Springer Nature","citation":{"short":"I.C. Fortunato, D. Brückner, S. Grosser, R. Nautiyal, L. Rossetti, M. Bosch-Padrós, J. Trebicka, P. Roca-Cusachs, R. Sunyer, E.B. Hannezo, X. Trepat, Nature Physics 21 (2025) 1638–1647.","mla":"Fortunato, Isabela Corina, et al. “Single-Cell Migration along and against Confined Haptotactic Gradients.” <i>Nature Physics</i>, vol. 21, Springer Nature, 2025, pp. 1638–47, doi:<a href=\"https://doi.org/10.1038/s41567-025-03015-3\">10.1038/s41567-025-03015-3</a>.","ista":"Fortunato IC, Brückner D, Grosser S, Nautiyal R, Rossetti L, Bosch-Padrós M, Trebicka J, Roca-Cusachs P, Sunyer R, Hannezo EB, Trepat X. 2025. Single-cell migration along and against confined haptotactic gradients. Nature Physics. 21, 1638–1647.","chicago":"Fortunato, Isabela Corina, David Brückner, Steffen Grosser, Rohit Nautiyal, Leone Rossetti, Miquel Bosch-Padrós, Jonel Trebicka, et al. “Single-Cell Migration along and against Confined Haptotactic Gradients.” <i>Nature Physics</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41567-025-03015-3\">https://doi.org/10.1038/s41567-025-03015-3</a>.","ieee":"I. C. Fortunato <i>et al.</i>, “Single-cell migration along and against confined haptotactic gradients,” <i>Nature Physics</i>, vol. 21. Springer Nature, pp. 1638–1647, 2025.","apa":"Fortunato, I. C., Brückner, D., Grosser, S., Nautiyal, R., Rossetti, L., Bosch-Padrós, M., … Trepat, X. (2025). Single-cell migration along and against confined haptotactic gradients. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03015-3\">https://doi.org/10.1038/s41567-025-03015-3</a>","ama":"Fortunato IC, Brückner D, Grosser S, et al. Single-cell migration along and against confined haptotactic gradients. <i>Nature Physics</i>. 2025;21:1638-1647. doi:<a href=\"https://doi.org/10.1038/s41567-025-03015-3\">10.1038/s41567-025-03015-3</a>"},"date_created":"2025-10-05T22:01:36Z","department":[{"_id":"EdHa"}],"page":"1638-1647","status":"public","month":"10","date_published":"2025-10-01T00:00:00Z","project":[{"grant_number":"ALTF 343-2022","name":"A mechano-chemical theory for stem cell fate decisions in organoid development","_id":"34e2a5b5-11ca-11ed-8bc3-b2265616ef0b"}],"quality_controlled":"1","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"intvolume":"        21","_id":"20431","author":[{"last_name":"Fortunato","first_name":"Isabela Corina","full_name":"Fortunato, Isabela Corina"},{"full_name":"Brückner, David","id":"e1e86031-6537-11eb-953a-f7ab92be508d","orcid":"0000-0001-7205-2975","first_name":"David","last_name":"Brückner"},{"full_name":"Grosser, Steffen","first_name":"Steffen","last_name":"Grosser"},{"first_name":"Rohit","last_name":"Nautiyal","full_name":"Nautiyal, Rohit"},{"first_name":"Leone","last_name":"Rossetti","full_name":"Rossetti, Leone"},{"last_name":"Bosch-Padrós","first_name":"Miquel","full_name":"Bosch-Padrós, Miquel"},{"last_name":"Trebicka","first_name":"Jonel","full_name":"Trebicka, Jonel"},{"full_name":"Roca-Cusachs, Pere","first_name":"Pere","last_name":"Roca-Cusachs"},{"first_name":"Raimon","last_name":"Sunyer","full_name":"Sunyer, Raimon"},{"first_name":"Edouard B","last_name":"Hannezo","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-6005-1561","full_name":"Hannezo, Edouard B"},{"first_name":"Xavier","last_name":"Trepat","full_name":"Trepat, Xavier"}],"external_id":{"isi":["001581659900001"]},"OA_place":"repository","isi":1,"oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank all the members of our groups for discussions and support. We thank A. Menéndez, S. Usieto, M. Purciolas and E. Coderch for technical assistance. We thank G. Charras (London Centre for Nanotechnology, UK) and M. Sheetz (Columbia University, USA) for sharing cells used in this work. We thank J. Ivaska (University of Turku, Finland) for sharing integrin α5-GFP DNA plasmid. We thank P. Guillamat for technical advice and A. Labernardie for providing the microfluidic channels. We thank M. Gómez-González for sharing the 2D traction microscopy algorithm. Finally, we thank P. Guillamat, J. Abenza, G. Ceada, L. Faure, E. Dalaka, M. Matejčić, A. Beedle, I. Granero, O. Baguer, A. Albajar and N. Chahare for discussions. This paper was funded by the Generalitat de Catalunya (Grant Nos. AGAUR SGR-2017-01602 to X.T. and 2021 SGR 00523 to R.S. and the CERCA Programme and ICREA Academia awards to P.R.-C.), the Spanish Ministry for Science and Innovation MICCINN/FEDER (Grant Nos. PID2021-128635NB-I00, MCIN/AEI/10.13039/501100011033 and ERDF-EU A way of making Europe to X.T., PID2021-128674OB-I00 and CNS2022-135533 to R.S. and PID2019-110298GB-I00 to P.R.-C.), the European Research Council (Grant Nos. 101097753 to P.R.-C. and Adv-883739 to X.T.), Fundació la Marató de TV3 (Project Award 201903-30-31-32 to X.T.), the European Commission (Grant No. H2020-FETPROACT-01-2016-731957 to P.R.-C. and X.T.) and La Caixa Foundation (Grant No. LCF/PR/HR20/52400004 to P.R.-C. and X.T.). R.S. is a Serra-Hunter fellow. D.B.B. was supported by the NOMIS foundation as a NOMIS fellow, by the European Molecular Biology Organization (Postdoctoral Fellowship ALTF 343-2022) and by the Austrian Academy of Sciences through an APART-MINT Fellowship. I.C.F. acknowledges support from the European Foundation for the Study of Chronic Liver Failure. IBEC is recipient of a Severo Ochoa Award of Excellence from MINECO.","article_type":"original","article_processing_charge":"No","date_updated":"2026-01-05T14:26:28Z","publication":"Nature Physics","type":"journal_article","scopus_import":"1","main_file_link":[{"url":"https://doi.org/10.1101/2024.12.02.626413","open_access":"1"}],"publication_status":"published","doi":"10.1038/s41567-025-03015-3","title":"Single-cell migration along and against confined haptotactic gradients","volume":21,"year":"2025","day":"01","OA_type":"green","oa":1,"abstract":[{"lang":"eng","text":"Haptotaxis is the process of directed cell migration along gradients of extracellular matrix density and is central to morphogenesis, immune responses and cancer invasion. It is commonly assumed that cells respond to these gradients by migrating directionally towards the regions of highest ligand density. In contrast with this view, here we show that cells exposed to micropatterned fibronectin gradients exhibit a wide range of complex trajectories, including directed haptotactic migration up the gradient but also linear oscillations and circles with extended periods of migration down the gradient. To explain this behaviour, we developed a biophysical model of haptotactic cell migration based on a coarse-grained molecular clutch model coupled to persistent stochastic polarity dynamics. Although initial haptotactic migration is explained by the differential friction at the front and back of the cell, the observed complex trajectories over longer timescales arise from the interplay between differential friction, persistence and physical confinement. Overall, our study reveals that confinement and persistence modulate the ability of cells to sense and respond to haptotactic cues and provides a framework for understanding how cells navigate complex environments."}],"corr_author":"1","language":[{"iso":"eng"}]},{"article_type":"original","article_processing_charge":"No","date_updated":"2026-01-05T13:25:59Z","type":"journal_article","publication":"Nature Physics","scopus_import":"1","publication_status":"published","doi":"10.1038/s41567-025-03001-9","volume":21,"title":"Chiral phonons","year":"2025","day":"01","OA_type":"closed access","abstract":[{"lang":"eng","text":"A rapidly increasing body of work reporting phenomena associated with lattice vibrations carrying angular momentum has led to the emergence of the field of chiral phonons. Some of these properties, such as the phonon magnetic moment, also occur in achiral phonons that are circularly or elliptically polarized, while the presence of chirality has additional implications for the types of interaction allowed between the phonons and light, electrons and other quasiparticles. In this Perspective we introduce a framework for classifying phonons with angular momentum, and provide illustrations of the different types using examples from the recent literature. Specifically, we suggest the term ‘axial phonon’ to encompass all phonons that carry angular momentum, real or pseudo, and reserve the term ‘chiral phonon’ for those phonons that break improper rotational symmetry. We hope that this scheme provides clarification on the matter of phonon chirality and will serve as a guide for future research."}],"language":[{"iso":"eng"}],"citation":{"short":"D.M. Juraschek, R.M. Geilhufe, H. Zhu, M. Basini, P. Baum, A. Baydin, S. Chaudhary, M. Fechner, B. Flebus, G. Grissonnanche, A.I. Kirilyuk, M. Lemeshko, S.F. Maehrlein, M. Mignolet, S. Murakami, Q. Niu, U. Nowak, C.P. Romao, H. Rostami, T. Satoh, N.A. Spaldin, H. Ueda, L. Zhang, Nature Physics 21 (2025) 1532–1540.","mla":"Juraschek, Dominik M., et al. “Chiral Phonons.” <i>Nature Physics</i>, vol. 21, Springer Nature, 2025, pp. 1532–40, doi:<a href=\"https://doi.org/10.1038/s41567-025-03001-9\">10.1038/s41567-025-03001-9</a>.","ista":"Juraschek DM, Geilhufe RM, Zhu H, Basini M, Baum P, Baydin A, Chaudhary S, Fechner M, Flebus B, Grissonnanche G, Kirilyuk AI, Lemeshko M, Maehrlein SF, Mignolet M, Murakami S, Niu Q, Nowak U, Romao CP, Rostami H, Satoh T, Spaldin NA, Ueda H, Zhang L. 2025. Chiral phonons. Nature Physics. 21, 1532–1540.","chicago":"Juraschek, Dominik M., R. Matthias Geilhufe, Hanyu Zhu, Martina Basini, Peter Baum, Andrey Baydin, Swati Chaudhary, et al. “Chiral Phonons.” <i>Nature Physics</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41567-025-03001-9\">https://doi.org/10.1038/s41567-025-03001-9</a>.","apa":"Juraschek, D. M., Geilhufe, R. M., Zhu, H., Basini, M., Baum, P., Baydin, A., … Zhang, L. (2025). Chiral phonons. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03001-9\">https://doi.org/10.1038/s41567-025-03001-9</a>","ieee":"D. M. Juraschek <i>et al.</i>, “Chiral phonons,” <i>Nature Physics</i>, vol. 21. Springer Nature, pp. 1532–1540, 2025.","ama":"Juraschek DM, Geilhufe RM, Zhu H, et al. Chiral phonons. <i>Nature Physics</i>. 2025;21:1532-1540. doi:<a href=\"https://doi.org/10.1038/s41567-025-03001-9\">10.1038/s41567-025-03001-9</a>"},"publisher":"Springer Nature","date_created":"2025-10-05T22:01:37Z","department":[{"_id":"MiLe"}],"page":"1532-1540","status":"public","month":"10","date_published":"2025-10-01T00:00:00Z","quality_controlled":"1","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"intvolume":"        21","_id":"20432","author":[{"last_name":"Juraschek","first_name":"Dominik M.","full_name":"Juraschek, Dominik M."},{"full_name":"Geilhufe, R. Matthias","first_name":"R. Matthias","last_name":"Geilhufe"},{"last_name":"Zhu","first_name":"Hanyu","full_name":"Zhu, Hanyu"},{"first_name":"Martina","last_name":"Basini","full_name":"Basini, Martina"},{"full_name":"Baum, Peter","last_name":"Baum","first_name":"Peter"},{"full_name":"Baydin, Andrey","first_name":"Andrey","last_name":"Baydin"},{"last_name":"Chaudhary","first_name":"Swati","full_name":"Chaudhary, Swati"},{"last_name":"Fechner","first_name":"Michael","full_name":"Fechner, Michael"},{"last_name":"Flebus","first_name":"Benedetta","full_name":"Flebus, Benedetta"},{"last_name":"Grissonnanche","first_name":"Gael","full_name":"Grissonnanche, Gael"},{"last_name":"Kirilyuk","first_name":"Andrei I.","full_name":"Kirilyuk, Andrei I."},{"full_name":"Lemeshko, Mikhail","orcid":"0000-0002-6990-7802","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","first_name":"Mikhail","last_name":"Lemeshko"},{"last_name":"Maehrlein","first_name":"Sebastian F.","full_name":"Maehrlein, Sebastian F."},{"last_name":"Mignolet","first_name":"Maxime","full_name":"Mignolet, Maxime"},{"full_name":"Murakami, Shuichi","last_name":"Murakami","first_name":"Shuichi"},{"last_name":"Niu","first_name":"Qian","full_name":"Niu, Qian"},{"full_name":"Nowak, Ulrich","first_name":"Ulrich","last_name":"Nowak"},{"full_name":"Romao, Carl P.","first_name":"Carl P.","last_name":"Romao"},{"full_name":"Rostami, Habib","first_name":"Habib","last_name":"Rostami"},{"full_name":"Satoh, Takuya","first_name":"Takuya","last_name":"Satoh"},{"full_name":"Spaldin, Nicola A.","first_name":"Nicola A.","last_name":"Spaldin"},{"full_name":"Ueda, Hiroki","last_name":"Ueda","first_name":"Hiroki"},{"full_name":"Zhang, Lifa","first_name":"Lifa","last_name":"Zhang"}],"external_id":{"isi":["001575765100001"]},"isi":1,"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank A. V. Balatsky, E. Bousquet, A. Disa, S. Kamba, L. Klebl, R. Merlin, A. Srivastava, A. Stroppa, M. Udina, P. Wong and D. Xiao for valuable discussions. M.B. acknowledges support from SNSF Ambizione project number PZ00P2_216089. P.B. and U.N. acknowledge funding from the Deutsche Forschungsgemeinschaft (grant number 541503763). B.F. acknowledges support from the National Science Foundation under grant number NSF DMR-2144086. G.G. acknowledges support from STeP2 number ANR-22-EXES-0013, QuantExt number ANR-23-CE30-0001-01, Audace CEA number ANR-24-RRII-0004 and the École Polytechnique foundation. A.I.K. acknowledges the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO-I) for their financial contribution, including the support of the HFML-FELIX Laboratory. D.M.J. acknowledges support from Tel Aviv University and ERC Starting Grant CHIRALPHONONICS grant number 101166037. S.F.M. acknowledges funding from the Deutsche Forschungsgemeinschaft (grant number 469405347). C.P.R. and N.A.S. were supported by ETH Zurich and by the European Union and Horizon 2020, grant agreement numbers 810451 and 101030352. R.M.G. acknowledges support from the Swedish Research Council (VR starting grant number 2022-03350), the Olle Engkvist Foundation (grant number 229-0443), the Royal Physiographic Society in Lund (Horisont), the Knut and Alice Wallenberg Foundation (grant number 2023.0087) and Chalmers University of Technology via the Department of Physics and the Areas of Advance Nano and Materials Science. Q.N. is supported by the National Natural Science Foundation of China (grant number 12234017) and the National Key Research and Development Program of China (grant number 2023YFA1406300). H.R. acknowledges funding from the Engineering and Physical Sciences Research Council (grant number UKRI122) and Royal Society (grant number IES\\R2\\242309). T.S. acknowledges support from MEXT X-NICS (grant number JPJ011438), NINS OML Project (grant number OML012301) and JST CREST (grant number JPMJCR24R5). H.Z. acknowledges support from the Welch Foundation (grant number C-2128) and the National Science Foundation (grant number DMR-2240106). We acknowledge support from the Centre Européen de Calcul Atomique et Moléculaire (CECAM) in connection to organizing the workshop \"Chiral Phonons in Quantum Materials\", held in 2023, where the idea for this paper emerged."},{"article_type":"original","article_processing_charge":"Yes","scopus_import":"1","ddc":["000"],"type":"journal_article","publication":"Nature Communications","PlanS_conform":"1","date_updated":"2026-02-16T12:21:50Z","publication_status":"published","doi":"10.1038/s41467-025-63852-x","file_date_updated":"2025-10-13T07:54:51Z","abstract":[{"text":"Accurate modeling of long-range forces is critical in atomistic simulations, as they play a central role in determining the properties of material and chemical systems. However, standard machine learning interatomic potentials (MLIPs) often rely on short-range approximations, limiting their applicability to systems with significant electrostatics and dispersion forces. We recently introduced the Latent Ewald Summation (LES) method, which captures long-range electrostatics without explicitly learning atomic charges or charge equilibration. We benchmark LES on diverse and challenging systems, including charged molecules, ionic liquids, electrolyte solutions, polar dipeptides, surface adsorption, electrolyte/solid interfaces, and solid-solid interfaces. Here we show that LES can reproduce the exact atomic charges for classical systems with fixed charges and can infer dipole and quadrupole moments, as well as the dipole derivative with respect to atomic positions, for quantum mechanical systems. Moreover, LES can achieve better accuracy in energy and force predictions compared to methods that explicitly learn from charges.","lang":"eng"}],"corr_author":"1","language":[{"iso":"eng"}],"article_number":"8763","year":"2025","volume":16,"title":"Machine learning of charges and long-range interactions from energies and forces","oa":1,"day":"01","OA_type":"gold","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"month":"10","status":"public","citation":{"ieee":"D. S. King, D. Kim, P. Zhong, and B. Cheng, “Machine learning of charges and long-range interactions from energies and forces,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","ama":"King DS, Kim D, Zhong P, Cheng B. Machine learning of charges and long-range interactions from energies and forces. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-63852-x\">10.1038/s41467-025-63852-x</a>","apa":"King, D. S., Kim, D., Zhong, P., &#38; Cheng, B. (2025). Machine learning of charges and long-range interactions from energies and forces. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-63852-x\">https://doi.org/10.1038/s41467-025-63852-x</a>","chicago":"King, Daniel S., Dongjin Kim, Peichen Zhong, and Bingqing Cheng. “Machine Learning of Charges and Long-Range Interactions from Energies and Forces.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-63852-x\">https://doi.org/10.1038/s41467-025-63852-x</a>.","ista":"King DS, Kim D, Zhong P, Cheng B. 2025. Machine learning of charges and long-range interactions from energies and forces. Nature Communications. 16, 8763.","mla":"King, Daniel S., et al. “Machine Learning of Charges and Long-Range Interactions from Energies and Forces.” <i>Nature Communications</i>, vol. 16, 8763, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-63852-x\">10.1038/s41467-025-63852-x</a>.","short":"D.S. King, D. Kim, P. Zhong, B. Cheng, Nature Communications 16 (2025)."},"publisher":"Springer Nature","department":[{"_id":"BiCh"}],"date_created":"2025-10-12T22:01:25Z","_id":"20452","publication_identifier":{"eissn":["2041-1723"]},"intvolume":"        16","date_published":"2025-10-01T00:00:00Z","quality_controlled":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","external_id":{"pmid":["41034200"],"isi":["001586620700015"]},"DOAJ_listed":"1","pmid":1,"author":[{"first_name":"Daniel S.","last_name":"King","full_name":"King, Daniel S."},{"first_name":"Dongjin","last_name":"Kim","full_name":"Kim, Dongjin"},{"last_name":"Zhong","first_name":"Peichen","full_name":"Zhong, Peichen"},{"full_name":"Cheng, Bingqing","orcid":"0000-0002-3584-9632","id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","last_name":"Cheng","first_name":"Bingqing"}],"isi":1,"OA_place":"publisher","file":[{"access_level":"open_access","relation":"main_file","date_created":"2025-10-13T07:54:51Z","file_name":"2025_NatureComm_King.pdf","success":1,"checksum":"34b6005d349bbff85839c4e51d6c8725","file_size":4907055,"date_updated":"2025-10-13T07:54:51Z","file_id":"20460","content_type":"application/pdf","creator":"dernst"}],"has_accepted_license":"1","acknowledgement":"We thank Chunyi Zhang for providing the TiO2(101)/NaCl+NaOH+HCl(aq) dataset and for useful discussions. We thank Jia-Xin Zhu for providing the Pt(111)/KF(aq) dataset. We thank Tsz Wai Ko and Jonas Finkler for useful discussions and for the DFT-optimized Au2-MgO(001) structures. We thank Junmin Chen for discussions. D.K and B.C. acknowledge funding from Toyota Research Institute Synthesis Advanced Research Challenge. D.S.K. and P.Z. acknowledge funding from BIDMaP Postdoctoral Fellowship."},{"article_type":"original","article_processing_charge":"Yes (via OA deal)","ddc":["530"],"scopus_import":"1","PlanS_conform":"1","date_updated":"2025-12-01T12:43:33Z","publication":"Journal of Physics Condensed Matter","type":"journal_article","publication_status":"published","doi":"10.1088/1361-648X/ae0913","file_date_updated":"2025-10-13T06:34:15Z","abstract":[{"text":"Magnetotropic susceptibility is the thermodynamic coefficient that maps the curvature of free energy with respect to an applied magnetic field orientation, providing a means to quantify the magnetic anisotropy of a crystal. In this context, non-linear magnetic torque behavior has been reported in FePS3, motivating the investigation of similar non-linear characteristics in its magnetotropic susceptibility. In this work, we derive the non-linear magnetotropic susceptibility expressions for FePS3 in both ac*-and bc*-planes using complementary approaches: by taking the first derivative of torque and through the formal calculation of the magnetotropic susceptibility. Higher-order terms in the magnetization are included, and the final equations are obtained by applying symmetry constraints imposed by the C2h point group of the material. We analyze the behavior of the resulting non-linear expressions and identify the contributions of each parameter. Our theoretical results show good agreement with preliminary, unpublished experimental data, offering meaningful guidance for ongoing and future experimental work.","lang":"eng"}],"corr_author":"1","language":[{"iso":"eng"}],"article_number":"405801","volume":37,"title":"Non-linear magnetotropic susceptibility in FePS3","year":"2025","day":"06","OA_type":"hybrid","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"status":"public","month":"10","citation":{"ieee":"H. Farooq and M. Nauman, “Non-linear magnetotropic susceptibility in FePS3,” <i>Journal of Physics Condensed Matter</i>, vol. 37, no. 40. IOP Publishing, 2025.","apa":"Farooq, H., &#38; Nauman, M. (2025). Non-linear magnetotropic susceptibility in FePS3. <i>Journal of Physics Condensed Matter</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1361-648X/ae0913\">https://doi.org/10.1088/1361-648X/ae0913</a>","ama":"Farooq H, Nauman M. Non-linear magnetotropic susceptibility in FePS3. <i>Journal of Physics Condensed Matter</i>. 2025;37(40). doi:<a href=\"https://doi.org/10.1088/1361-648X/ae0913\">10.1088/1361-648X/ae0913</a>","chicago":"Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility in FePS3.” <i>Journal of Physics Condensed Matter</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/1361-648X/ae0913\">https://doi.org/10.1088/1361-648X/ae0913</a>.","ista":"Farooq H, Nauman M. 2025. Non-linear magnetotropic susceptibility in FePS3. Journal of Physics Condensed Matter. 37(40), 405801.","mla":"Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility in FePS3.” <i>Journal of Physics Condensed Matter</i>, vol. 37, no. 40, 405801, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/1361-648X/ae0913\">10.1088/1361-648X/ae0913</a>.","short":"H. Farooq, M. Nauman, Journal of Physics Condensed Matter 37 (2025)."},"publisher":"IOP Publishing","department":[{"_id":"KiMo"}],"date_created":"2025-10-12T22:01:26Z","intvolume":"        37","issue":"40","publication_identifier":{"eissn":["1361-648X"],"issn":["0953-8984"]},"_id":"20453","date_published":"2025-10-06T00:00:00Z","quality_controlled":"1","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","pmid":1,"author":[{"first_name":"Hamza","last_name":"Farooq","full_name":"Farooq, Hamza"},{"id":"32c21954-2022-11eb-9d5f-af9f93c24e71","full_name":"Nauman, Muhammad","orcid":"0000-0002-2111-4846","last_name":"Nauman","first_name":"Muhammad"}],"external_id":{"isi":["001585824100001"],"pmid":["40967257"]},"isi":1,"OA_place":"publisher","has_accepted_license":"1","acknowledgement":"We thank Kimberly A. Modic for her support and discussions regarding the technique in the context of a project indirectly related to, but distinct from, the present work. We also thank Brad J. Ramshaw and Arkady Shekhter for scientific discussions not directly related to this study, but whose insights proved helpful. We are grateful to Valeska Zambra, Amit Nathwani, Hamza Nasir, and Tayyaba Hussain for informal discussions on various aspects of the technique, and to Naoya Iwahara for his thoughtful and constructive feedback. The experimental curve shown in figures 3(b) and 6, from the Thermodynamics of Quantum Materials (TQM) group at ISTA, was measured by Muhammad Nauman for an unrelated project. We thank Kimberly Modic for granting access to the laboratory facilities. Je Geun Park provided the crystal used for that measurement via Younjung Jo, whose contribution we gratefully acknowledge. Institutional support from the Institute of Science and Technology Austria (ISTA) is also gratefully acknowledged.","file":[{"date_created":"2025-10-13T06:34:15Z","access_level":"open_access","relation":"main_file","file_name":"2025_JourPhysicsCondMatter_Farooq.pdf","file_size":1709516,"success":1,"checksum":"b182856a5a655496e149afa49ec464f3","file_id":"20458","date_updated":"2025-10-13T06:34:15Z","creator":"dernst","content_type":"application/pdf"}]},{"article_processing_charge":"No","article_type":"original","ddc":["520"],"scopus_import":"1","PlanS_conform":"1","date_updated":"2026-02-19T09:32:04Z","type":"journal_article","publication":"Astronomy & Astrophysics","doi":"10.1051/0004-6361/202555213","publication_status":"published","file_date_updated":"2025-10-13T07:05:55Z","language":[{"iso":"eng"}],"article_number":"A253","abstract":[{"text":"Context. γ Dor stars are ideal targets for studies of the innermost dynamical properties of stars, due to their rich asteroseismic spectrum of gravity modes. Integrating internal magnetism to the picture appears as the next milestone of detailed asteroseismic studies, for its prime importance on stellar evolution. The inertial dip in prograde dipole modes period-spacing pattern of γ Dors stands out as a unique window on the convective core structure and dynamics. Recent studies have highlighted the dependence of the dip structure on core density stratification, the contrast of the near-core Brunt-Väisälä frequency and rotation rate, as well as the core-to-near-core differential rotation. In addition, the effect of envelope magnetism has been derived on low-frequency magneto-gravito-inertial waves.\r\n\r\nAims. We revisited the inertial dip formation including core and envelope magnetism, and explored the probing power of this feature on dynamo-generated core fields.\r\n\r\nMethods. We considered as a first step a toroidal magnetic field with a bi-layer (core and envelope) Alfvén frequency. This configuration allowed us to revisit the coupling problem using our knowledge on both core magneto-inertial modes and envelope magneto-gravito-inertial modes. Using this configuration, we were able to stay in an analytical framework to exhibit the magnetic effects on the inertial dip shape and location. This configuration allowed a laboratory to be set up that moves us towards the comprehension of magnetic effects on the dip structure.\r\n\r\nResults. We show a shift of the inertial dip towards lower spin parameter values and a thinner dip with increasing core magnetic field’s strength, quite similar to the signature of differential rotation. The magnetic effects become sizeable when the ratio of the magnetic to the Coriolis effects is high enough. We explored the potential degeneracy of the magnetic effects with differential rotation. We studied the detectability of core magnetism, considering both observational constraints on the periods of the modes and potential gravito-inertial mode suppression.","lang":"eng"}],"corr_author":"1","OA_type":"diamond","day":"01","oa":1,"volume":701,"title":"Exploring the probing power of γ Dor's inertial dip for core magnetism: The case of a toroidal field","year":"2025","status":"public","month":"09","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_created":"2025-10-12T22:01:26Z","department":[{"_id":"LiBu"},{"_id":"GradSch"}],"publisher":"EDP Sciences","citation":{"chicago":"Barrault, Lucas, Lisa Annabelle Bugnet, S. Mathis, and J. S.G. Mombarg. “Exploring the Probing Power of γ Dor’s Inertial Dip for Core Magnetism: The Case of a Toroidal Field.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href=\"https://doi.org/10.1051/0004-6361/202555213\">https://doi.org/10.1051/0004-6361/202555213</a>.","ista":"Barrault L, Bugnet LA, Mathis S, Mombarg JSG. 2025. Exploring the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field. Astronomy &#38; Astrophysics. 701, A253.","mla":"Barrault, Lucas, et al. “Exploring the Probing Power of γ Dor’s Inertial Dip for Core Magnetism: The Case of a Toroidal Field.” <i>Astronomy &#38; Astrophysics</i>, vol. 701, A253, EDP Sciences, 2025, doi:<a href=\"https://doi.org/10.1051/0004-6361/202555213\">10.1051/0004-6361/202555213</a>.","short":"L. Barrault, L.A. Bugnet, S. Mathis, J.S.G. Mombarg, Astronomy &#38; Astrophysics 701 (2025).","ieee":"L. Barrault, L. A. Bugnet, S. Mathis, and J. S. G. Mombarg, “Exploring the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.","apa":"Barrault, L., Bugnet, L. A., Mathis, S., &#38; Mombarg, J. S. G. (2025). Exploring the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202555213\">https://doi.org/10.1051/0004-6361/202555213</a>","ama":"Barrault L, Bugnet LA, Mathis S, Mombarg JSG. Exploring the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field. <i>Astronomy &#38; Astrophysics</i>. 2025;701. doi:<a href=\"https://doi.org/10.1051/0004-6361/202555213\">10.1051/0004-6361/202555213</a>"},"publication_identifier":{"eissn":["1432-0746"],"issn":["0004-6361"]},"intvolume":"       701","_id":"20454","project":[{"_id":"914d8549-16d5-11f0-9cad-bbe6324c93a9","name":"Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology","grant_number":"101165631"}],"quality_controlled":"1","date_published":"2025-09-01T00:00:00Z","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","isi":1,"author":[{"id":"4471a8fd-32c1-11ee-a9a4-fb670d398f64","full_name":"Barrault, Lucas","last_name":"Barrault","first_name":"Lucas"},{"first_name":"Lisa Annabelle","last_name":"Bugnet","orcid":"0000-0003-0142-4000","id":"d9edb345-f866-11ec-9b37-d119b5234501","full_name":"Bugnet, Lisa Annabelle"},{"first_name":"S.","last_name":"Mathis","full_name":"Mathis, S."},{"first_name":"J. S.G.","last_name":"Mombarg","full_name":"Mombarg, J. S.G."}],"arxiv":1,"external_id":{"arxiv":["2507.00308"],"isi":["001585834500002"]},"has_accepted_license":"1","acknowledgement":"We thank the referee for their comments and suggestions which allowed us to improve the quality of this manuscript. L. Barrault and L. Bugnet gratefully acknowledge support from the European Research Council (ERC) under the Horizon Europe programme (Calcifer; Starting Grant agreement N°101165631). S. Mathis acknowledges support from the PLATO CNES grant at CEA/DAp. S. Mathis and J.S.G. Mombarg acknowledge support from the European Research Council through HORIZON ERC SyG Grant 4D-STAR 101071505. While partially funded by the European Union, views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. L. Barrault thanks T. Van Reeth and C. Aerts for their invaluable teachings. The authors thank also the members of the Asteroseismology and Stellar Dynamics group of the Institute of Science and Technology Austria (ISTA) for very useful discussion: A. Cristea, L. Einramhof, K. M. Smith, S. Torres.","file":[{"date_created":"2025-10-13T07:05:55Z","relation":"main_file","access_level":"open_access","file_size":2503149,"success":1,"checksum":"2c209b33119af4a251bab4a418a21075","file_name":"2025_AstronomyAstrophysics_BarraultL.pdf","date_updated":"2025-10-13T07:05:55Z","file_id":"20459","creator":"dernst","content_type":"application/pdf"}]},{"scopus_import":"1","date_updated":"2025-10-13T07:18:26Z","type":"conference","publication":"2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops","article_processing_charge":"No","abstract":[{"lang":"eng","text":"Despite extensive research since the community learned about adversarial examples 10 years ago, we still do not know how to train high-accuracy classifiers that are guaranteed to be robust to small perturbations of their inputs. Previous works often argued that this might be because no classifier exists that is robust and accurate at the same time. However, in computer vision this assumption does not match reality where humans are usually accurate and robust on most tasks of interest. We offer an alternative explanation and show that in certain settings robust generalization is only possible with unrealistically large amounts of data. Specifically, we find a setting where a robust classifier exists, it is easy to learn an accurate classifier, yet it requires an exponential amount of data to learn a robust classifier. Based on this theoretical result, we evaluate the influence of the amount of training data on datasets such as CIFAR10. Our findings indicate that the the amount of training data is the main factor determining the robust performance. Furthermore we show that that there are low magnitude directions in the data which are useful for non-robust generalization but are not available for robust classifiers. This implies that robust classification is a strictly harder tasks than normal classification, thereby providing an explanation why robust classification requires more data."}],"corr_author":"1","language":[{"iso":"eng"}],"title":"Intriguing properties of robust classification","year":"2025","conference":{"location":"Nashville, TN, United States","end_date":"2025-06-12","name":"CVPR: Conference on Computer Vision and Pattern Recognition","start_date":"2025-06-11"},"OA_type":"green","day":"15","oa":1,"publication_status":"published","doi":"10.1109/CVPRW67362.2025.00071","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2412.04245","open_access":"1"}],"publication_identifier":{"isbn":["9798331599942"],"issn":["2160-7508"],"eissn":["2160-7516"]},"_id":"20455","date_published":"2025-06-15T00:00:00Z","quality_controlled":"1","page":"660-669","status":"public","month":"06","publisher":"IEEE","citation":{"ieee":"B. Prach and C. Lampert, “Intriguing properties of robust classification,” in <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>, Nashville, TN, United States, 2025, pp. 660–669.","ama":"Prach B, Lampert C. Intriguing properties of robust classification. In: <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>. IEEE; 2025:660-669. doi:<a href=\"https://doi.org/10.1109/CVPRW67362.2025.00071\">10.1109/CVPRW67362.2025.00071</a>","apa":"Prach, B., &#38; Lampert, C. (2025). Intriguing properties of robust classification. In <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i> (pp. 660–669). Nashville, TN, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPRW67362.2025.00071\">https://doi.org/10.1109/CVPRW67362.2025.00071</a>","ista":"Prach B, Lampert C. 2025. Intriguing properties of robust classification. 2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops. CVPR: Conference on Computer Vision and Pattern Recognition, 660–669.","mla":"Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.” <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>, IEEE, 2025, pp. 660–69, doi:<a href=\"https://doi.org/10.1109/CVPRW67362.2025.00071\">10.1109/CVPRW67362.2025.00071</a>.","short":"B. Prach, C. Lampert, in:, 2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops, IEEE, 2025, pp. 660–669.","chicago":"Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.” In <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>, 660–69. IEEE, 2025. <a href=\"https://doi.org/10.1109/CVPRW67362.2025.00071\">https://doi.org/10.1109/CVPRW67362.2025.00071</a>."},"department":[{"_id":"ChLa"}],"date_created":"2025-10-12T22:01:26Z","related_material":{"record":[{"relation":"earlier_version","id":"18874","status":"public"}]},"oa_version":"Preprint","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"full_name":"Prach, Bernd","id":"2D561D42-C427-11E9-89B4-9C1AE6697425","first_name":"Bernd","last_name":"Prach"},{"full_name":"Lampert, Christoph","orcid":"0000-0001-8622-7887","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph","last_name":"Lampert"}],"external_id":{"arxiv":["2412.04245"]},"arxiv":1,"OA_place":"repository"},{"acknowledgement":"This work was supported by Biological Services teams at both the Laboratory of Molecular Biology and Ares facilities. The authors are very grateful to Prof. Helmut Kessels and Dr. Hinze Ho for initial discussions that led to this study, Dr. Andrew Penn for constructive feedback on the project, Xinyao Dou for comments on the study, and Profs. Peter Jonas and Roger Nicoll for feedback on the manuscript. Funding was provided by the Medical Research Council (MRC – MC_U105174197 to I.H.G.) and the European Union's Horizon 2020 programme through a Marie Skłodowska-Curie Actions Individual Fellowship (MSCA-IF 101026635 to J.F.W.).","has_accepted_license":"1","file":[{"date_created":"2026-01-05T13:13:06Z","relation":"main_file","access_level":"open_access","success":1,"file_size":10875254,"checksum":"3326e49795f44a7c51c16ecbcce58cde","file_name":"2025_JourPhysiology_Greger.pdf","file_id":"20949","date_updated":"2026-01-05T13:13:06Z","creator":"dernst","content_type":"application/pdf"}],"related_material":{"link":[{"relation":"software","url":"https://github.com/jakefwatson/miniplace"}]},"oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","isi":1,"OA_place":"publisher","pmid":1,"author":[{"full_name":"Greger, Ingo H.","first_name":"Ingo H.","last_name":"Greger"},{"id":"63836096-4690-11EA-BD4E-32803DDC885E","full_name":"Watson, Jake","orcid":"0000-0002-8698-3823","first_name":"Jake","last_name":"Watson"}],"external_id":{"isi":["001581924700001"],"pmid":["41015537"]},"issue":"22","intvolume":"       603","publication_identifier":{"issn":["0022-3751"],"eissn":["1469-7793"]},"_id":"20457","quality_controlled":"1","project":[{"name":"Synaptic computations of the hippocampal CA3 circuitry","_id":"fc2be41b-9c52-11eb-aca3-faa90aa144e9","call_identifier":"H2020","grant_number":"101026635"}],"date_published":"2025-11-15T00:00:00Z","status":"public","month":"11","page":"7189-7205","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_created":"2025-10-12T22:01:27Z","department":[{"_id":"PeJo"}],"publisher":"Wiley","citation":{"short":"I.H. Greger, J. Watson, Journal of Physiology 603 (2025) 7189–7205.","mla":"Greger, Ingo H., and Jake Watson. “‘Mini Analysis’ Misrepresents Changes in Synaptic Properties Due to Incomplete Event Detection.” <i>Journal of Physiology</i>, vol. 603, no. 22, Wiley, 2025, pp. 7189–205, doi:<a href=\"https://doi.org/10.1113/JP288183\">10.1113/JP288183</a>.","ista":"Greger IH, Watson J. 2025. ‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection. Journal of Physiology. 603(22), 7189–7205.","chicago":"Greger, Ingo H., and Jake Watson. “‘Mini Analysis’ Misrepresents Changes in Synaptic Properties Due to Incomplete Event Detection.” <i>Journal of Physiology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1113/JP288183\">https://doi.org/10.1113/JP288183</a>.","ama":"Greger IH, Watson J. ‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection. <i>Journal of Physiology</i>. 2025;603(22):7189-7205. doi:<a href=\"https://doi.org/10.1113/JP288183\">10.1113/JP288183</a>","ieee":"I. H. Greger and J. Watson, “‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection,” <i>Journal of Physiology</i>, vol. 603, no. 22. Wiley, pp. 7189–7205, 2025.","apa":"Greger, I. H., &#38; Watson, J. (2025). ‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection. <i>Journal of Physiology</i>. Wiley. <a href=\"https://doi.org/10.1113/JP288183\">https://doi.org/10.1113/JP288183</a>"},"language":[{"iso":"eng"}],"abstract":[{"text":"Patch-clamp recording of miniature postsynaptic currents (mPSCs, or ‘minis’) is used extensively to investigate the functional properties of synapses. With this approach, spontaneous synaptic transmission events are recorded in an attempt to determine quantal synaptic parameters or the effect of synaptic manipulations. However, at the majority of brain synapses these events are small, with many undetectable due to recording noise. The effects of incomplete detection were well appreciated in the early years of synaptic physiology analysis, but appear to be increasingly forgotten. Here we sought to characterise the consequences of incomplete detection on the interpretability of mini analysis, using simulated mPSC data to give full control over event parameters. We demonstrate that commonly reported measures such as mean event amplitude and frequency, are misrepresented by the loss of undetected events. Probabilistic loss of small events results in detected event amplitude distributions that appear biologically complete, yet do not reflect the underlying synaptic properties. With both simulated and experimental datasets, we demonstrate that specific changes in event amplitude are primarily detected as changes in frequency, compromising classical biological interpretations. To facilitate more robust data analysis and interpretation, we detail a means for experimental estimation of the event detection limit and provide practical recommendations for data analysis. Together, our study highlights how mini analysis is prone to falsely reporting synaptic changes, raising awareness of these considerations, and provides a framework for more robust data analysis and interpretation.","lang":"eng"}],"corr_author":"1","day":"15","OA_type":"hybrid","oa":1,"volume":603,"title":"‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection","year":"2025","doi":"10.1113/JP288183","publication_status":"published","file_date_updated":"2026-01-05T13:13:06Z","ec_funded":1,"ddc":["570"],"scopus_import":"1","PlanS_conform":"1","date_updated":"2026-01-05T13:13:32Z","type":"journal_article","publication":"Journal of Physiology","article_processing_charge":"Yes (in subscription journal)","article_type":"original"},{"article_processing_charge":"Yes (via OA deal)","article_type":"original","ddc":["530"],"scopus_import":"1","date_updated":"2025-12-01T15:02:16Z","PlanS_conform":"1","publication":"Physical Review Letters","type":"journal_article","doi":"10.1103/72b9-c8cq","publication_status":"published","file_date_updated":"2025-10-23T11:57:20Z","ec_funded":1,"language":[{"iso":"eng"}],"article_number":"148002","abstract":[{"lang":"eng","text":"An electric double-layer capacitor (EDLC) stores energy by modulating the spatial distribution of ions in the electrolytic solution that it contains. We determine the mean-field timescales for planar EDLC relaxation to equilibrium after a potential difference is applied. We tackle first the fully symmetric case, where positive and negative ionic species have the same valence and diffusivity, and then the general, more complex, asymmetric case. Depending on the applied voltage and salt concentration, different regimes appear, revealing a remarkably rich phenomenology relevant for nanocapacitors."}],"corr_author":"1","day":"29","OA_type":"hybrid","oa":1,"title":"Charging dynamics of electric double-layer nanocapacitors in mean field","volume":135,"year":"2025","status":"public","month":"09","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"date_created":"2025-10-16T13:09:30Z","department":[{"_id":"AnSa"}],"publisher":"American Physical Society","citation":{"chicago":"Palaia, Ivan, Adelchi J. Asta, Megh Dutta, Patrick B. Warren, Benjamin Rotenberg, and Emmanuel Trizac. “Charging Dynamics of Electric Double-Layer Nanocapacitors in Mean Field.” <i>Physical Review Letters</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/72b9-c8cq\">https://doi.org/10.1103/72b9-c8cq</a>.","ista":"Palaia I, Asta AJ, Dutta M, Warren PB, Rotenberg B, Trizac E. 2025. Charging dynamics of electric double-layer nanocapacitors in mean field. Physical Review Letters. 135(14), 148002.","short":"I. Palaia, A.J. Asta, M. Dutta, P.B. Warren, B. Rotenberg, E. Trizac, Physical Review Letters 135 (2025).","mla":"Palaia, Ivan, et al. “Charging Dynamics of Electric Double-Layer Nanocapacitors in Mean Field.” <i>Physical Review Letters</i>, vol. 135, no. 14, 148002, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/72b9-c8cq\">10.1103/72b9-c8cq</a>.","ieee":"I. Palaia, A. J. Asta, M. Dutta, P. B. Warren, B. Rotenberg, and E. Trizac, “Charging dynamics of electric double-layer nanocapacitors in mean field,” <i>Physical Review Letters</i>, vol. 135, no. 14. American Physical Society, 2025.","apa":"Palaia, I., Asta, A. J., Dutta, M., Warren, P. B., Rotenberg, B., &#38; Trizac, E. (2025). Charging dynamics of electric double-layer nanocapacitors in mean field. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/72b9-c8cq\">https://doi.org/10.1103/72b9-c8cq</a>","ama":"Palaia I, Asta AJ, Dutta M, Warren PB, Rotenberg B, Trizac E. Charging dynamics of electric double-layer nanocapacitors in mean field. <i>Physical Review Letters</i>. 2025;135(14). doi:<a href=\"https://doi.org/10.1103/72b9-c8cq\">10.1103/72b9-c8cq</a>"},"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"intvolume":"       135","issue":"14","_id":"20477","quality_controlled":"1","project":[{"grant_number":"101034413","call_identifier":"H2020","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"date_published":"2025-09-29T00:00:00Z","oa_version":"Published Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_place":"publisher","isi":1,"author":[{"orcid":" 0000-0002-8843-9485 ","full_name":"Palaia, Ivan","id":"9c805cd2-4b75-11ec-a374-db6dd0ed57fa","first_name":"Ivan","last_name":"Palaia"},{"full_name":"Asta, Adelchi J.","first_name":"Adelchi J.","last_name":"Asta"},{"last_name":"Dutta","first_name":"Megh","full_name":"Dutta, Megh"},{"first_name":"Patrick B.","last_name":"Warren","full_name":"Warren, Patrick B."},{"full_name":"Rotenberg, Benjamin","first_name":"Benjamin","last_name":"Rotenberg"},{"first_name":"Emmanuel","last_name":"Trizac","full_name":"Trizac, Emmanuel"}],"arxiv":1,"external_id":{"arxiv":["2301.00610"],"isi":["001587121300010"]},"has_accepted_license":"1","acknowledgement":"This work has received funding from the European Union’s Horizon 2020 and Horizon Europe research and innovation programs under the Marie Skłodowska-Curie Grants No. 674979-NANOTRANS (I. P., P. B. W., B. R., E. T.), No. 101034413 (I. P.), and No. 101119598-FLUXIONIC (M. D., B. R., E. T.), as well as from the European Research Council under Grant No. 863473 (B. R.). B. R. acknowledges financial support from the French Agence Nationale de la Recherche (ANR) under Grant No. ANR-21-CE29-0021-02 (DIADEM). I. P. thanks Anđela Šarić for further support at ISTA.","file":[{"access_level":"open_access","relation":"main_file","date_created":"2025-10-23T11:57:20Z","file_name":"2025_PhysReviewLetters_Palaia.pdf","file_size":480414,"checksum":"e29809fea48b18217d1779980f7117c4","success":1,"date_updated":"2025-10-23T11:57:20Z","file_id":"20526","content_type":"application/pdf","creator":"dernst"}]}]
