[{"year":"2020","date_created":"2020-05-04T08:50:47Z","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":9,"date_updated":"2023-08-21T06:17:12Z","ddc":["580"],"date_published":"2020-04-08T00:00:00Z","abstract":[{"lang":"eng","text":"Hormonal signalling in animals often involves direct transcription factor-hormone interactions that modulate gene expression. In contrast, plant hormone signalling is most commonly based on de-repression via the degradation of transcriptional repressors. Recently, we uncovered a non-canonical signalling mechanism for the plant hormone auxin whereby auxin directly affects the activity of the atypical auxin response factor (ARF), ETTIN towards target genes without the requirement for protein degradation. Here we show that ETTIN directly binds auxin, leading to dissociation from co-repressor proteins of the TOPLESS/TOPLESS-RELATED family followed by histone acetylation and induction of gene expression. This mechanism is reminiscent of animal hormone signalling as it affects the activity towards regulation of target genes and provides the first example of a DNA-bound hormone receptor in plants. Whilst auxin affects canonical ARFs indirectly by facilitating degradation of Aux/IAA repressors, direct ETTIN-auxin interactions allow switching between repressive and de-repressive chromatin states in an instantly-reversible manner."}],"doi":"10.7554/elife.51787","publication_status":"published","external_id":{"isi":["000527752200001"],"pmid":["32267233"]},"department":[{"_id":"JiFr"}],"file":[{"content_type":"application/pdf","date_created":"2020-05-04T09:06:43Z","relation":"main_file","checksum":"15d740de1a741fdcc6ec128c48eed017","file_id":"7794","file_size":2893082,"date_updated":"2020-07-14T12:48:03Z","file_name":"2020_eLife_Kuhn.pdf","access_level":"open_access","creator":"dernst"}],"intvolume":"         9","publication":"eLife","file_date_updated":"2020-07-14T12:48:03Z","month":"04","quality_controlled":"1","publication_identifier":{"issn":["2050-084X"]},"article_number":"e51787","publisher":"eLife Sciences Publications","type":"journal_article","day":"08","status":"public","language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"André","last_name":"Kuhn","full_name":"Kuhn, André"},{"first_name":"Sigurd","last_name":"Ramans Harborough","full_name":"Ramans Harborough, Sigurd"},{"last_name":"McLaughlin","full_name":"McLaughlin, Heather M","first_name":"Heather M"},{"full_name":"Natarajan, Bhavani","last_name":"Natarajan","first_name":"Bhavani"},{"last_name":"Verstraeten","full_name":"Verstraeten, Inge","orcid":"0000-0001-7241-2328","id":"362BF7FE-F248-11E8-B48F-1D18A9856A87","first_name":"Inge"},{"id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","last_name":"Friml","first_name":"Jiří"},{"last_name":"Kepinski","full_name":"Kepinski, Stefan","first_name":"Stefan"},{"first_name":"Lars","last_name":"Østergaard","full_name":"Østergaard, Lars"}],"article_type":"original","article_processing_charge":"No","_id":"7793","oa_version":"Published Version","scopus_import":"1","isi":1,"title":"Direct ETTIN-auxin interaction controls chromatin states in gynoecium development","citation":{"mla":"Kuhn, André, et al. “Direct ETTIN-Auxin Interaction Controls Chromatin States in Gynoecium Development.” <i>ELife</i>, vol. 9, e51787, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/elife.51787\">10.7554/elife.51787</a>.","chicago":"Kuhn, André, Sigurd Ramans Harborough, Heather M McLaughlin, Bhavani Natarajan, Inge Verstraeten, Jiří Friml, Stefan Kepinski, and Lars Østergaard. “Direct ETTIN-Auxin Interaction Controls Chromatin States in Gynoecium Development.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/elife.51787\">https://doi.org/10.7554/elife.51787</a>.","ista":"Kuhn A, Ramans Harborough S, McLaughlin HM, Natarajan B, Verstraeten I, Friml J, Kepinski S, Østergaard L. 2020. Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. eLife. 9, e51787.","apa":"Kuhn, A., Ramans Harborough, S., McLaughlin, H. M., Natarajan, B., Verstraeten, I., Friml, J., … Østergaard, L. (2020). Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/elife.51787\">https://doi.org/10.7554/elife.51787</a>","short":"A. Kuhn, S. Ramans Harborough, H.M. McLaughlin, B. Natarajan, I. Verstraeten, J. Friml, S. Kepinski, L. Østergaard, ELife 9 (2020).","ama":"Kuhn A, Ramans Harborough S, McLaughlin HM, et al. Direct ETTIN-auxin interaction controls chromatin states in gynoecium development. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/elife.51787\">10.7554/elife.51787</a>","ieee":"A. Kuhn <i>et al.</i>, “Direct ETTIN-auxin interaction controls chromatin states in gynoecium development,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020."},"has_accepted_license":"1","pmid":1},{"oa":1,"language":[{"iso":"eng"}],"author":[{"first_name":"Artur","full_name":"Czumaj, Artur","orcid":"0000-0002-5646-9524","last_name":"Czumaj"},{"first_name":"Peter","id":"11396234-BB50-11E9-B24C-90FCE5697425","orcid":"0000-0002-5646-9524","full_name":"Davies, Peter","last_name":"Davies"},{"first_name":"Merav","last_name":"Parter","full_name":"Parter, Merav"}],"article_processing_charge":"No","_id":"7802","issue":"7","month":"07","quality_controlled":"1","publisher":"Association for Computing Machinery","day":"01","type":"conference","status":"public","page":"175-185","arxiv":1,"citation":{"ista":"Czumaj A, Davies P, Parter M. 2020. Graph sparsification for derandomizing massively parallel computation with low space. Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020). SPAA: Symposium on Parallelism in Algorithms and Architectures, 175–185.","apa":"Czumaj, A., Davies, P., &#38; Parter, M. (2020). Graph sparsification for derandomizing massively parallel computation with low space. In <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i> (pp. 175–185). Virtual Event, United States: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3350755.3400282\">https://doi.org/10.1145/3350755.3400282</a>","short":"A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020), Association for Computing Machinery, 2020, pp. 175–185.","ama":"Czumaj A, Davies P, Parter M. Graph sparsification for derandomizing massively parallel computation with low space. In: <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>. Association for Computing Machinery; 2020:175-185. doi:<a href=\"https://doi.org/10.1145/3350755.3400282\">10.1145/3350755.3400282</a>","ieee":"A. Czumaj, P. Davies, and M. Parter, “Graph sparsification for derandomizing massively parallel computation with low space,” in <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, Virtual Event, United States, 2020, no. 7, pp. 175–185.","chicago":"Czumaj, Artur, Peter Davies, and Merav Parter. “Graph Sparsification for Derandomizing Massively Parallel Computation with Low Space.” In <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, 175–85. Association for Computing Machinery, 2020. <a href=\"https://doi.org/10.1145/3350755.3400282\">https://doi.org/10.1145/3350755.3400282</a>.","mla":"Czumaj, Artur, et al. “Graph Sparsification for Derandomizing Massively Parallel Computation with Low Space.” <i>Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)</i>, no. 7, Association for Computing Machinery, 2020, pp. 175–85, doi:<a href=\"https://doi.org/10.1145/3350755.3400282\">10.1145/3350755.3400282</a>."},"scopus_import":"1","oa_version":"Preprint","isi":1,"related_material":{"record":[{"id":"9541","status":"public","relation":"later_version"}]},"title":"Graph sparsification for derandomizing massively parallel computation with low space","date_updated":"2025-04-15T06:54:47Z","conference":{"location":"Virtual Event, United States","start_date":"2020-07-15","name":"SPAA: Symposium on Parallelism in Algorithms and Architectures","end_date":"2020-07-17"},"date_published":"2020-07-01T00:00:00Z","project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"year":"2020","date_created":"2020-05-06T08:53:34Z","main_file_link":[{"url":"https://arxiv.org/abs/1912.05390","open_access":"1"}],"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","publication":"Proceedings of the 32nd ACM Symposium on Parallelism in Algorithms and Architectures (SPAA 2020)","ec_funded":1,"abstract":[{"lang":"eng","text":"The Massively Parallel Computation (MPC) model is an emerging model which distills core  aspects of distributed and parallel computation. It has been developed as a tool to solve (typically graph) problems in systems where the input is distributed over many machines with limited space.\r\n\t\r\nRecent work has focused on the regime in which machines have sublinear (in $n$, the number of nodes in the input graph) space, with randomized algorithms presented for fundamental graph problems of Maximal Matching and Maximal Independent Set. However, there have been no prior corresponding deterministic algorithms.\r\n\t\r\n\tA major challenge underlying the sublinear space setting is that the local space of each machine might be too small to store all the edges incident to a single node. This poses a considerable obstacle compared to the classical models in which each node is assumed to know and have easy access to its incident edges. To overcome this barrier we introduce a new graph sparsification technique that deterministically computes a low-degree subgraph with additional desired properties. The degree of the nodes in this subgraph is small in the sense that the edges of each node can be now stored on a single machine. This low-degree subgraph also has the property that solving the problem on this subgraph provides \\emph{significant} global progress, i.e., progress towards solving the problem for the original input graph.\r\n\t\r\nUsing this framework to derandomize the well-known randomized algorithm of Luby [SICOMP'86], we obtain $O(\\log \\Delta+\\log\\log n)$-round deterministic MPC algorithms for solving the fundamental problems of Maximal Matching and Maximal Independent Set with $O(n^{\\epsilon})$ space on each machine for any constant $\\epsilon > 0$. Based on the recent work of Ghaffari et al. [FOCS'18], this additive $O(\\log\\log n)$ factor is conditionally essential. These algorithms can also be shown to run in $O(\\log \\Delta)$ rounds in the closely related model of CONGESTED CLIQUE, improving upon the state-of-the-art bound of $O(\\log^2 \\Delta)$ rounds by Censor-Hillel et al. [DISC'17]."}],"doi":"10.1145/3350755.3400282","publication_status":"published","department":[{"_id":"DaAl"}],"external_id":{"isi":["000744436200015"],"arxiv":["1912.05390"]}},{"month":"07","quality_controlled":"1","publisher":"Association for Computing Machinery","day":"01","type":"conference","status":"public","page":"309-318","language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Artur","orcid":"0000-0002-5646-9524","full_name":"Czumaj, Artur","last_name":"Czumaj"},{"first_name":"Peter","last_name":"Davies","orcid":"0000-0002-5646-9524","full_name":"Davies, Peter","id":"11396234-BB50-11E9-B24C-90FCE5697425"},{"full_name":"Parter, Merav","last_name":"Parter","first_name":"Merav"}],"article_processing_charge":"No","_id":"7803","oa_version":"Submitted Version","scopus_import":"1","isi":1,"title":"Simple, deterministic, constant-round coloring in the congested clique","arxiv":1,"citation":{"chicago":"Czumaj, Artur, Peter Davies, and Merav Parter. “Simple, Deterministic, Constant-Round Coloring in the Congested Clique.” In <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, 309–18. Association for Computing Machinery, 2020. <a href=\"https://doi.org/10.1145/3382734.3405751\">https://doi.org/10.1145/3382734.3405751</a>.","mla":"Czumaj, Artur, et al. “Simple, Deterministic, Constant-Round Coloring in the Congested Clique.” <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2020, pp. 309–18, doi:<a href=\"https://doi.org/10.1145/3382734.3405751\">10.1145/3382734.3405751</a>.","ieee":"A. Czumaj, P. Davies, and M. Parter, “Simple, deterministic, constant-round coloring in the congested clique,” in <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>, Salerno, Italy, 2020, pp. 309–318.","short":"A. Czumaj, P. Davies, M. Parter, in:, Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2020, pp. 309–318.","ama":"Czumaj A, Davies P, Parter M. Simple, deterministic, constant-round coloring in the congested clique. In: <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2020:309-318. doi:<a href=\"https://doi.org/10.1145/3382734.3405751\">10.1145/3382734.3405751</a>","ista":"Czumaj A, Davies P, Parter M. 2020. Simple, deterministic, constant-round coloring in the congested clique. Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 309–318.","apa":"Czumaj, A., Davies, P., &#38; Parter, M. (2020). Simple, deterministic, constant-round coloring in the congested clique. In <i>Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing</i> (pp. 309–318). Salerno, Italy: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3382734.3405751\">https://doi.org/10.1145/3382734.3405751</a>"},"has_accepted_license":"1","year":"2020","date_created":"2020-05-06T09:02:14Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","date_updated":"2025-09-10T10:18:18Z","conference":{"start_date":"2020-08-03","location":"Salerno, Italy","end_date":"2020-08-07","name":"PODC: Symposium on Principles of Distributed Computing"},"date_published":"2020-07-01T00:00:00Z","project":[{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"ddc":["000"],"ec_funded":1,"abstract":[{"lang":"eng","text":"We settle the complexity of the (Δ+1)-coloring and (Δ+1)-list coloring problems in the CONGESTED CLIQUE model by presenting a simple deterministic algorithm for both problems running in a constant number of rounds. This matches the complexity of the recent breakthrough randomized constant-round (Δ+1)-list coloring algorithm due to Chang et al. (PODC'19), and significantly improves upon the state-of-the-art O(logΔ)-round deterministic (Δ+1)-coloring bound of Parter (ICALP'18).\r\nA remarkable property of our algorithm is its simplicity. Whereas the state-of-the-art randomized algorithms for this problem are based on the quite involved local coloring algorithm of Chang et al. (STOC'18), our algorithm can be described in just a few lines. At a high level, it applies a careful derandomization of a recursive procedure which partitions the nodes and their respective palettes into separate bins. We show that after O(1) recursion steps, the remaining uncolored subgraph within each bin has linear size, and thus can be solved locally by collecting it to a single node. This algorithm can also be implemented in the Massively Parallel Computation (MPC) model provided that each machine has linear (in n, the number of nodes in the input graph) space.\r\nWe also show an extension of our algorithm to the MPC regime in which machines have sublinear space: we present the first deterministic (Δ+1)-list coloring algorithm designed for sublinear-space MPC, which runs in O(logΔ+loglogn) rounds."}],"doi":"10.1145/3382734.3405751","publication_status":"published","department":[{"_id":"DaAl"}],"external_id":{"arxiv":["2009.06043"],"isi":["001436693500042"]},"publication":"Proceedings of the 2020 ACM Symposium on Principles of Distributed Computing","file":[{"file_name":"ColoringArxiv.pdf","file_size":520051,"date_updated":"2020-10-08T08:17:36Z","access_level":"open_access","creator":"pdavies","success":1,"content_type":"application/pdf","date_created":"2020-10-08T08:17:36Z","relation":"main_file","file_id":"8624","checksum":"46fe4fc58a64eb04068115573f631d4c"}],"file_date_updated":"2020-10-08T08:17:36Z"},{"file_date_updated":"2020-07-14T12:48:03Z","publication":"Nature Communications","file":[{"file_id":"7817","checksum":"dce367abf2c1a1d15f58fe6f7de82893","relation":"main_file","date_created":"2020-05-11T10:36:33Z","content_type":"application/pdf","creator":"dernst","access_level":"open_access","file_name":"2020_NatureComm_Flynn.pdf","date_updated":"2020-07-14T12:48:03Z","file_size":4609120}],"intvolume":"        11","publication_status":"published","external_id":{"pmid":["32350248"],"isi":["000531855500029"]},"department":[{"_id":"MaDe"}],"abstract":[{"lang":"eng","text":"Besides pro-inflammatory roles, the ancient cytokine interleukin-17 (IL-17) modulates neural circuit function. We investigate IL-17 signaling in neurons, and the extent it can alter organismal phenotypes. We combine immunoprecipitation and mass spectrometry to biochemically characterize endogenous signaling complexes that function downstream of IL-17 receptors in C. elegans neurons. We identify the paracaspase MALT-1 as a critical output of the pathway. MALT1 mediates signaling from many immune receptors in mammals, but was not previously implicated in IL-17 signaling or nervous system function. C. elegans MALT-1 forms a complex with homologs of Act1 and IRAK and appears to function both as a scaffold and a protease. MALT-1 is expressed broadly in the C. elegans nervous system, and neuronal IL-17–MALT-1 signaling regulates multiple phenotypes, including escape behavior, associative learning, immunity and longevity. Our data suggest MALT1 has an ancient role modulating neural circuit function downstream of IL-17 to remodel physiology and behavior."}],"doi":"10.1038/s41467-020-15872-y","ddc":["570"],"date_published":"2020-04-29T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":11,"date_updated":"2026-04-03T09:27:08Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2020","date_created":"2020-05-10T22:00:47Z","pmid":1,"citation":{"chicago":"Flynn, Sean M., Changchun Chen, Murat Artan, Stephen Barratt, Alastair Crisp, Geoffrey M. Nelson, Sew Yeu Peak-Chew, Farida Begum, Mark Skehel, and Mario de Bono. “MALT-1 Mediates IL-17 Neural Signaling to Regulate C. Elegans Behavior, Immunity and Longevity.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-15872-y\">https://doi.org/10.1038/s41467-020-15872-y</a>.","mla":"Flynn, Sean M., et al. “MALT-1 Mediates IL-17 Neural Signaling to Regulate C. Elegans Behavior, Immunity and Longevity.” <i>Nature Communications</i>, vol. 11, 2099, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-15872-y\">10.1038/s41467-020-15872-y</a>.","ista":"Flynn SM, Chen C, Artan M, Barratt S, Crisp A, Nelson GM, Peak-Chew SY, Begum F, Skehel M, de Bono M. 2020. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. Nature Communications. 11, 2099.","apa":"Flynn, S. M., Chen, C., Artan, M., Barratt, S., Crisp, A., Nelson, G. M., … de Bono, M. (2020). MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-15872-y\">https://doi.org/10.1038/s41467-020-15872-y</a>","short":"S.M. Flynn, C. Chen, M. Artan, S. Barratt, A. Crisp, G.M. Nelson, S.Y. Peak-Chew, F. Begum, M. Skehel, M. de Bono, Nature Communications 11 (2020).","ama":"Flynn SM, Chen C, Artan M, et al. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-15872-y\">10.1038/s41467-020-15872-y</a>","ieee":"S. M. Flynn <i>et al.</i>, “MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020."},"has_accepted_license":"1","title":"MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity","oa_version":"Published Version","scopus_import":"1","isi":1,"article_type":"original","article_processing_charge":"No","corr_author":"1","_id":"7804","language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Sean M.","last_name":"Flynn","full_name":"Flynn, Sean M."},{"first_name":"Changchun","full_name":"Chen, Changchun","last_name":"Chen"},{"first_name":"Murat","id":"C407B586-6052-11E9-B3AE-7006E6697425","last_name":"Artan","full_name":"Artan, Murat","orcid":"0000-0001-8945-6992"},{"full_name":"Barratt, Stephen","last_name":"Barratt","first_name":"Stephen"},{"last_name":"Crisp","full_name":"Crisp, Alastair","first_name":"Alastair"},{"full_name":"Nelson, Geoffrey M.","last_name":"Nelson","first_name":"Geoffrey M."},{"last_name":"Peak-Chew","full_name":"Peak-Chew, Sew Yeu","first_name":"Sew Yeu"},{"last_name":"Begum","full_name":"Begum, Farida","first_name":"Farida"},{"first_name":"Mark","last_name":"Skehel","full_name":"Skehel, Mark"},{"id":"4E3FF80E-F248-11E8-B48F-1D18A9856A87","last_name":"De Bono","full_name":"De Bono, Mario","orcid":"0000-0001-8347-0443","first_name":"Mario"}],"type":"journal_article","day":"29","status":"public","quality_controlled":"1","month":"04","article_number":"2099","publisher":"Springer Nature","publication_identifier":{"eissn":["2041-1723"]}},{"date_created":"2020-05-10T22:00:48Z","year":"2020","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_updated":"2026-04-02T14:32:53Z","volume":11,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_published":"2020-05-01T00:00:00Z","ddc":["570"],"project":[{"call_identifier":"FWF","grant_number":"I 1774-B16","_id":"2542D156-B435-11E9-9278-68D0E5697425","name":"Hormone cross-talk drives nutrient dependent plant development"},{"name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"doi":"10.1038/s41467-020-15895-5","ec_funded":1,"abstract":[{"text":"Plants as non-mobile organisms constantly integrate varying environmental signals to flexibly adapt their growth and development. Local fluctuations in water and nutrient availability, sudden changes in temperature or other abiotic and biotic stresses can trigger changes in the growth of plant organs. Multiple mutually interconnected hormonal signaling cascades act as essential endogenous translators of these exogenous signals in the adaptive responses of plants. Although the molecular backbones of hormone transduction pathways have been identified, the mechanisms underlying their interactions are largely unknown. Here, using genome wide transcriptome profiling we identify an auxin and cytokinin cross-talk component; SYNERGISTIC ON AUXIN AND CYTOKININ 1 (SYAC1), whose expression in roots is strictly dependent on both of these hormonal pathways. We show that SYAC1 is a regulator of secretory pathway, whose enhanced activity interferes with deposition of cell wall components and can fine-tune organ growth and sensitivity to soil pathogens.","lang":"eng"}],"department":[{"_id":"EvBe"}],"external_id":{"isi":["000531425900012"],"pmid":["32358503"]},"publication_status":"published","intvolume":"        11","publication":"Nature Communications","file":[{"content_type":"application/pdf","success":1,"date_created":"2020-10-06T07:47:53Z","relation":"main_file","file_id":"8614","checksum":"2cba327c9e9416d75cb96be54b0fb441","file_size":4743576,"file_name":"2020_NatureComm_Hurny.pdf","date_updated":"2020-10-06T07:47:53Z","access_level":"open_access","creator":"dernst"}],"file_date_updated":"2020-10-06T07:47:53Z","article_number":"2170","publisher":"Springer Nature","publication_identifier":{"eissn":["2041-1723"]},"quality_controlled":"1","month":"05","status":"public","day":"01","type":"journal_article","author":[{"id":"4DC4AF46-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3638-1426","full_name":"Hurny, Andrej","last_name":"Hurny","first_name":"Andrej"},{"orcid":"0000-0003-1923-2410","full_name":"Cuesta, Candela","last_name":"Cuesta","id":"33A3C818-F248-11E8-B48F-1D18A9856A87","first_name":"Candela"},{"id":"457160E6-F248-11E8-B48F-1D18A9856A87","last_name":"Cavallari","full_name":"Cavallari, Nicola","first_name":"Nicola"},{"first_name":"Krisztina","full_name":"Ötvös, Krisztina","orcid":"0000-0002-5503-4983","last_name":"Ötvös","id":"29B901B0-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Duclercq","full_name":"Duclercq, Jerome","first_name":"Jerome"},{"first_name":"Ladislav","full_name":"Dokládal, Ladislav","last_name":"Dokládal"},{"id":"310A8E3E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9179-6099","full_name":"Montesinos López, Juan C","last_name":"Montesinos López","first_name":"Juan C"},{"first_name":"Marçal","last_name":"Gallemi","orcid":"0000-0003-4675-6893","full_name":"Gallemi, Marçal","id":"460C6802-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Hana","id":"42FE702E-F248-11E8-B48F-1D18A9856A87","last_name":"Semeradova","full_name":"Semeradova, Hana"},{"full_name":"Rauter, Thomas","last_name":"Rauter","id":"A0385D1A-9376-11EA-A47D-9862C5E3AB22","first_name":"Thomas"},{"last_name":"Stenzel","full_name":"Stenzel, Irene","first_name":"Irene"},{"first_name":"Geert","full_name":"Persiau, Geert","last_name":"Persiau"},{"first_name":"Freia","last_name":"Benade","full_name":"Benade, Freia"},{"full_name":"Bhalearo, Rishikesh","last_name":"Bhalearo","first_name":"Rishikesh"},{"last_name":"Sýkorová","full_name":"Sýkorová, Eva","first_name":"Eva"},{"last_name":"Gorzsás","full_name":"Gorzsás, András","first_name":"András"},{"first_name":"Julien","full_name":"Sechet, Julien","last_name":"Sechet"},{"first_name":"Gregory","last_name":"Mouille","full_name":"Mouille, Gregory"},{"first_name":"Ingo","last_name":"Heilmann","full_name":"Heilmann, Ingo"},{"first_name":"Geert","full_name":"De Jaeger, Geert","last_name":"De Jaeger"},{"full_name":"Ludwig-Müller, Jutta","last_name":"Ludwig-Müller","first_name":"Jutta"},{"last_name":"Benková","orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","first_name":"Eva"}],"oa":1,"language":[{"iso":"eng"}],"_id":"7805","corr_author":"1","article_processing_charge":"No","article_type":"original","isi":1,"scopus_import":"1","acknowledgement":"We thank Daria Siekhaus, Jiri Friml and Alexander Johnson for critical reading of the manuscript, Peter Pimpl, Christian Luschnig and Liwen Jiang for sharing published material, Lesia Rodriguez Solovey for technical assistance. This work was supported by the Austrian Science Fund (FWF01_I1774S) to A.H., K.Ö., and E.B., the German Research Foundation (DFG; He3424/6-1 to I.H.), by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n° [291734] (to N.C.), by the EU in the framework of the Marie-Curie FP7 COFUND People Programme through the award of an AgreenSkills+ fellowship No. 609398 (to J.S.) and by the Scientific Service Units of IST-Austria through resources provided by the Bioimaging Facility, the Life Science Facility. The IJPB benefits from the support of Saclay Plant Sciences-SPS (ANR-17-EUR-0007).","oa_version":"Published Version","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"title":"Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance","has_accepted_license":"1","citation":{"ista":"Hurny A, Cuesta C, Cavallari N, Ötvös K, Duclercq J, Dokládal L, Montesinos López JC, Gallemi M, Semerádová H, Rauter T, Stenzel I, Persiau G, Benade F, Bhalearo R, Sýkorová E, Gorzsás A, Sechet J, Mouille G, Heilmann I, De Jaeger G, Ludwig-Müller J, Benková E. 2020. Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. Nature Communications. 11, 2170.","apa":"Hurny, A., Cuesta, C., Cavallari, N., Ötvös, K., Duclercq, J., Dokládal, L., … Benková, E. (2020). Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-020-15895-5\">https://doi.org/10.1038/s41467-020-15895-5</a>","ama":"Hurny A, Cuesta C, Cavallari N, et al. Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance. <i>Nature Communications</i>. 2020;11. doi:<a href=\"https://doi.org/10.1038/s41467-020-15895-5\">10.1038/s41467-020-15895-5</a>","ieee":"A. Hurny <i>et al.</i>, “Synergistic on Auxin and Cytokinin 1 positively regulates growth and attenuates soil pathogen resistance,” <i>Nature Communications</i>, vol. 11. Springer Nature, 2020.","short":"A. Hurny, C. Cuesta, N. Cavallari, K. Ötvös, J. Duclercq, L. Dokládal, J.C. Montesinos López, M. Gallemi, H. Semerádová, T. Rauter, I. Stenzel, G. Persiau, F. Benade, R. Bhalearo, E. Sýkorová, A. Gorzsás, J. Sechet, G. Mouille, I. Heilmann, G. De Jaeger, J. Ludwig-Müller, E. Benková, Nature Communications 11 (2020).","mla":"Hurny, Andrej, et al. “Synergistic on Auxin and Cytokinin 1 Positively Regulates Growth and Attenuates Soil Pathogen Resistance.” <i>Nature Communications</i>, vol. 11, 2170, Springer Nature, 2020, doi:<a href=\"https://doi.org/10.1038/s41467-020-15895-5\">10.1038/s41467-020-15895-5</a>.","chicago":"Hurny, Andrej, Candela Cuesta, Nicola Cavallari, Krisztina Ötvös, Jerome Duclercq, Ladislav Dokládal, Juan C Montesinos López, et al. “Synergistic on Auxin and Cytokinin 1 Positively Regulates Growth and Attenuates Soil Pathogen Resistance.” <i>Nature Communications</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1038/s41467-020-15895-5\">https://doi.org/10.1038/s41467-020-15895-5</a>."},"pmid":1},{"date_updated":"2026-06-18T19:27:16Z","volume":"2020-January","conference":{"start_date":"2020-01-05","location":"Salt Lake City, UT, United States","name":"SODA: Symposium on Discrete Algorithms","end_date":"2020-01-08"},"date_published":"2020-01-01T00:00:00Z","project":[{"grant_number":"P31312","_id":"26611F5C-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Algorithms for Embeddings and Homotopy Theory"}],"ddc":["500"],"year":"2020","date_created":"2020-05-10T22:00:48Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1137/1.9781611975994.47"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication":"Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms","abstract":[{"text":"We consider the following decision problem EMBEDk→d in computational topology (where k ≤ d are fixed positive integers): Given a finite simplicial complex K of dimension k, does there exist a (piecewise-linear) embedding of K into ℝd?\r\nThe special case EMBED1→2 is graph planarity, which is decidable in linear time, as shown by Hopcroft and Tarjan. In higher dimensions, EMBED2→3 and EMBED3→3 are known to be decidable (as well as NP-hard), and recent results of Čadek et al. in computational homotopy theory, in combination with the classical Haefliger–Weber theorem in geometric topology, imply that EMBEDk→d can be solved in polynomial time for any fixed pair (k, d) of dimensions in the so-called metastable range .\r\nHere, by contrast, we prove that EMBEDk→d is algorithmically undecidable for almost all pairs of dimensions outside the metastable range, namely for . This almost completely resolves the decidability vs. undecidability of EMBEDk→d in higher dimensions and establishes a sharp dichotomy between polynomial-time solvability and undecidability.\r\nOur result complements (and in a wide range of dimensions strengthens) earlier results of Matoušek, Tancer, and the second author, who showed that EMBEDk→d is undecidable for 4 ≤ k ϵ {d – 1, d}, and NP-hard for all remaining pairs (k, d) outside the metastable range and satisfying d ≥ 4.","lang":"eng"}],"doi":"10.1137/1.9781611975994.47","publication_status":"published","department":[{"_id":"UlWa"}],"language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Marek","id":"3E8AF77E-F248-11E8-B48F-1D18A9856A87","full_name":"Filakovský, Marek","last_name":"Filakovský"},{"last_name":"Wagner","orcid":"0000-0002-1494-0568","full_name":"Wagner, Uli","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","first_name":"Uli"},{"id":"3AA52972-F248-11E8-B48F-1D18A9856A87","full_name":"Zhechev, Stephan Y","last_name":"Zhechev","first_name":"Stephan Y"}],"article_processing_charge":"No","_id":"7806","quality_controlled":"1","month":"01","publisher":"SIAM","publication_identifier":{"isbn":["9781611975994"]},"day":"01","type":"conference","status":"public","page":"767-785","citation":{"ama":"Filakovský M, Wagner U, Zhechev SY. Embeddability of simplicial complexes is undecidable. In: <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Vol 2020-January. SIAM; 2020:767-785. doi:<a href=\"https://doi.org/10.1137/1.9781611975994.47\">10.1137/1.9781611975994.47</a>","short":"M. Filakovský, U. Wagner, S.Y. Zhechev, in:, Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2020, pp. 767–785.","ieee":"M. Filakovský, U. Wagner, and S. Y. Zhechev, “Embeddability of simplicial complexes is undecidable,” in <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Salt Lake City, UT, United States, 2020, vol. 2020–January, pp. 767–785.","ista":"Filakovský M, Wagner U, Zhechev SY. 2020. Embeddability of simplicial complexes is undecidable. Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms vol. 2020–January, 767–785.","apa":"Filakovský, M., Wagner, U., &#38; Zhechev, S. Y. (2020). Embeddability of simplicial complexes is undecidable. In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i> (Vol. 2020–January, pp. 767–785). Salt Lake City, UT, United States: SIAM. <a href=\"https://doi.org/10.1137/1.9781611975994.47\">https://doi.org/10.1137/1.9781611975994.47</a>","chicago":"Filakovský, Marek, Uli Wagner, and Stephan Y Zhechev. “Embeddability of Simplicial Complexes Is Undecidable.” In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 2020–January:767–85. SIAM, 2020. <a href=\"https://doi.org/10.1137/1.9781611975994.47\">https://doi.org/10.1137/1.9781611975994.47</a>.","mla":"Filakovský, Marek, et al. “Embeddability of Simplicial Complexes Is Undecidable.” <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, vol. 2020–January, SIAM, 2020, pp. 767–85, doi:<a href=\"https://doi.org/10.1137/1.9781611975994.47\">10.1137/1.9781611975994.47</a>."},"scopus_import":"1","oa_version":"Published Version","title":"Embeddability of simplicial complexes is undecidable"},{"publication":"Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms","publication_status":"published","external_id":{"arxiv":["2003.13557"]},"department":[{"_id":"UlWa"}],"abstract":[{"lang":"eng","text":"In a straight-line embedded triangulation of a point set P in the plane, removing an inner edge and—provided the resulting quadrilateral is convex—adding the other diagonal is called an edge flip. The (edge) flip graph has all triangulations as vertices, and a pair of triangulations is adjacent if they can be obtained from each other by an edge flip. The goal of this paper is to contribute to a better understanding of the flip graph, with an emphasis on its connectivity.\r\nFor sets in general position, it is known that every triangulation allows at least edge flips (a tight bound) which gives the minimum degree of any flip graph for n points. We show that for every point set P in general position, the flip graph is at least -vertex connected. Somewhat more strongly, we show that the vertex connectivity equals the minimum degree occurring in the flip graph, i.e. the minimum number of flippable edges in any triangulation of P, provided P is large enough. Finally, we exhibit some of the geometry of the flip graph by showing that the flip graph can be covered by 1-skeletons of polytopes of dimension (products of associahedra).\r\nA corresponding result ((n – 3)-vertex connectedness) can be shown for the bistellar flip graph of partial triangulations, i.e. the set of all triangulations of subsets of P which contain all extreme points of P. This will be treated separately in a second part."}],"doi":"10.1137/1.9781611975994.172","date_published":"2020-01-01T00:00:00Z","volume":"2020-January","date_updated":"2024-10-09T21:03:33Z","conference":{"end_date":"2020-01-08","name":"SODA: Symposium on Discrete Algorithms","location":"Salt Lake City, UT, United States","start_date":"2020-01-05"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2020","main_file_link":[{"url":"https://doi.org/10.1137/1.9781611975994.172","open_access":"1"}],"date_created":"2020-05-10T22:00:48Z","citation":{"mla":"Wagner, Uli, and Emo Welzl. “Connectivity of Triangulation Flip Graphs in the Plane (Part I: Edge Flips).” <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, vol. 2020–January, SIAM, 2020, pp. 2823–41, doi:<a href=\"https://doi.org/10.1137/1.9781611975994.172\">10.1137/1.9781611975994.172</a>.","chicago":"Wagner, Uli, and Emo Welzl. “Connectivity of Triangulation Flip Graphs in the Plane (Part I: Edge Flips).” In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 2020–January:2823–41. SIAM, 2020. <a href=\"https://doi.org/10.1137/1.9781611975994.172\">https://doi.org/10.1137/1.9781611975994.172</a>.","apa":"Wagner, U., &#38; Welzl, E. (2020). Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i> (Vol. 2020–January, pp. 2823–2841). Salt Lake City, UT, United States: SIAM. <a href=\"https://doi.org/10.1137/1.9781611975994.172\">https://doi.org/10.1137/1.9781611975994.172</a>","ista":"Wagner U, Welzl E. 2020. Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms vol. 2020–January, 2823–2841.","ieee":"U. Wagner and E. Welzl, “Connectivity of triangulation flip graphs in the plane (Part I: Edge flips),” in <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Salt Lake City, UT, United States, 2020, vol. 2020–January, pp. 2823–2841.","short":"U. Wagner, E. Welzl, in:, Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2020, pp. 2823–2841.","ama":"Wagner U, Welzl E. Connectivity of triangulation flip graphs in the plane (Part I: Edge flips). In: <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Vol 2020-January. SIAM; 2020:2823-2841. doi:<a href=\"https://doi.org/10.1137/1.9781611975994.172\">10.1137/1.9781611975994.172</a>"},"arxiv":1,"title":"Connectivity of triangulation flip graphs in the plane (Part I: Edge flips)","related_material":{"record":[{"status":"public","relation":"later_version","id":"12129"}]},"scopus_import":1,"oa_version":"Submitted Version","article_processing_charge":"No","_id":"7807","oa":1,"language":[{"iso":"eng"}],"author":[{"id":"36690CA2-F248-11E8-B48F-1D18A9856A87","full_name":"Wagner, Uli","orcid":"0000-0002-1494-0568","last_name":"Wagner","first_name":"Uli"},{"first_name":"Emo","full_name":"Welzl, Emo","last_name":"Welzl"}],"type":"conference","day":"01","page":"2823-2841","status":"public","quality_controlled":"1","month":"01","publisher":"SIAM","publication_identifier":{"isbn":["9781611975994"]}},{"project":[{"_id":"25832EC2-B435-11E9-9278-68D0E5697425","grant_number":"S 11407_N23","call_identifier":"FWF","name":"Rigorous Systems Engineering"},{"name":"Formal methods for the design and analysis of complex systems","call_identifier":"FWF","_id":"25F42A32-B435-11E9-9278-68D0E5697425","grant_number":"Z211"}],"ddc":["000"],"date_published":"2020-04-17T00:00:00Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":12079,"date_updated":"2026-04-16T09:46:07Z","conference":{"end_date":"2020-04-30","name":"TACAS: Tools and Algorithms for the Construction and Analysis of Systems","location":"Dublin, Ireland","start_date":"2020-04-25"},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2020","date_created":"2020-05-10T22:00:49Z","file_date_updated":"2020-07-14T12:48:03Z","intvolume":"     12079","publication":"International Conference on Tools and Algorithms for the Construction and Analysis of Systems","file":[{"date_created":"2020-05-26T12:48:15Z","content_type":"application/pdf","checksum":"f19905a42891fe5ce93d69143fa3f6fb","file_id":"7893","relation":"main_file","access_level":"open_access","file_size":2744030,"file_name":"2020_TACAS_Giacobbe.pdf","date_updated":"2020-07-14T12:48:03Z","creator":"dernst"}],"publication_status":"published","external_id":{"isi":["001288734300005"]},"department":[{"_id":"ToHe"}],"abstract":[{"lang":"eng","text":"Quantization converts neural networks into low-bit fixed-point computations which can be carried out by efficient integer-only hardware, and is standard practice for the deployment of neural networks on real-time embedded devices. However, like their real-numbered counterpart, quantized networks are not immune to malicious misclassification caused by adversarial attacks. We investigate how quantization affects a network’s robustness to adversarial attacks, which is a formal verification question. We show that neither robustness nor non-robustness are monotonic with changing the number of bits for the representation and, also, neither are preserved by quantization from a real-numbered network. For this reason, we introduce a verification method for quantized neural networks which, using SMT solving over bit-vectors, accounts for their exact, bit-precise semantics. We built a tool and analyzed the effect of quantization on a classifier for the MNIST dataset. We demonstrate that, compared to our method, existing methods for the analysis of real-numbered networks often derive false conclusions about their quantizations, both when determining robustness and when detecting attacks, and that existing methods for quantized networks often miss attacks. Furthermore, we applied our method beyond robustness, showing how the number of bits in quantization enlarges the gender bias of a predictor for students’ grades."}],"alternative_title":["LNCS"],"doi":"10.1007/978-3-030-45237-7_5","article_processing_charge":"No","corr_author":"1","_id":"7808","language":[{"iso":"eng"}],"oa":1,"author":[{"id":"3444EA5E-F248-11E8-B48F-1D18A9856A87","full_name":"Giacobbe, Mirco","orcid":"0000-0001-8180-0904","last_name":"Giacobbe","first_name":"Mirco"},{"first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87","last_name":"Henzinger","full_name":"Henzinger, Thomas A","orcid":"0000-0002-2985-7724"},{"first_name":"Mathias","id":"3DC22916-F248-11E8-B48F-1D18A9856A87","full_name":"Lechner, Mathias","last_name":"Lechner"}],"type":"conference","day":"17","page":"79-97","status":"public","quality_controlled":"1","month":"04","publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783030452360"]},"publisher":"Springer Nature","citation":{"mla":"Giacobbe, Mirco, et al. “How Many Bits Does It Take to Quantize Your Neural Network?” <i>International Conference on Tools and Algorithms for the Construction and Analysis of Systems</i>, vol. 12079, Springer Nature, 2020, pp. 79–97, doi:<a href=\"https://doi.org/10.1007/978-3-030-45237-7_5\">10.1007/978-3-030-45237-7_5</a>.","chicago":"Giacobbe, Mirco, Thomas A Henzinger, and Mathias Lechner. “How Many Bits Does It Take to Quantize Your Neural Network?” In <i>International Conference on Tools and Algorithms for the Construction and Analysis of Systems</i>, 12079:79–97. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/978-3-030-45237-7_5\">https://doi.org/10.1007/978-3-030-45237-7_5</a>.","ieee":"M. Giacobbe, T. A. Henzinger, and M. Lechner, “How many bits does it take to quantize your neural network?,” in <i>International Conference on Tools and Algorithms for the Construction and Analysis of Systems</i>, Dublin, Ireland, 2020, vol. 12079, pp. 79–97.","short":"M. Giacobbe, T.A. Henzinger, M. Lechner, in:, International Conference on Tools and Algorithms for the Construction and Analysis of Systems, Springer Nature, 2020, pp. 79–97.","ama":"Giacobbe M, Henzinger TA, Lechner M. How many bits does it take to quantize your neural network? In: <i>International Conference on Tools and Algorithms for the Construction and Analysis of Systems</i>. Vol 12079. Springer Nature; 2020:79-97. doi:<a href=\"https://doi.org/10.1007/978-3-030-45237-7_5\">10.1007/978-3-030-45237-7_5</a>","ista":"Giacobbe M, Henzinger TA, Lechner M. 2020. How many bits does it take to quantize your neural network? International Conference on Tools and Algorithms for the Construction and Analysis of Systems. TACAS: Tools and Algorithms for the Construction and Analysis of Systems, LNCS, vol. 12079, 79–97.","apa":"Giacobbe, M., Henzinger, T. A., &#38; Lechner, M. (2020). How many bits does it take to quantize your neural network? In <i>International Conference on Tools and Algorithms for the Construction and Analysis of Systems</i> (Vol. 12079, pp. 79–97). Dublin, Ireland: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-030-45237-7_5\">https://doi.org/10.1007/978-3-030-45237-7_5</a>"},"has_accepted_license":"1","title":"How many bits does it take to quantize your neural network?","related_material":{"record":[{"id":"11362","status":"public","relation":"dissertation_contains"}]},"scopus_import":"1","oa_version":"Published Version","isi":1},{"citation":{"ieee":"R. J. Beattie, S. Hippenmeyer, and F. Pauler, “SCOPES: Sparking curiosity through Open-Source platforms in education and science,” <i>Frontiers in Education</i>, vol. 5. Frontiers Media, 2020.","short":"R.J. Beattie, S. Hippenmeyer, F. Pauler, Frontiers in Education 5 (2020).","ama":"Beattie RJ, Hippenmeyer S, Pauler F. SCOPES: Sparking curiosity through Open-Source platforms in education and science. <i>Frontiers in Education</i>. 2020;5. doi:<a href=\"https://doi.org/10.3389/feduc.2020.00048\">10.3389/feduc.2020.00048</a>","apa":"Beattie, R. J., Hippenmeyer, S., &#38; Pauler, F. (2020). SCOPES: Sparking curiosity through Open-Source platforms in education and science. <i>Frontiers in Education</i>. Frontiers Media. <a href=\"https://doi.org/10.3389/feduc.2020.00048\">https://doi.org/10.3389/feduc.2020.00048</a>","ista":"Beattie RJ, Hippenmeyer S, Pauler F. 2020. SCOPES: Sparking curiosity through Open-Source platforms in education and science. Frontiers in Education. 5, 48.","chicago":"Beattie, Robert J, Simon Hippenmeyer, and Florian Pauler. “SCOPES: Sparking Curiosity through Open-Source Platforms in Education and Science.” <i>Frontiers in Education</i>. Frontiers Media, 2020. <a href=\"https://doi.org/10.3389/feduc.2020.00048\">https://doi.org/10.3389/feduc.2020.00048</a>.","mla":"Beattie, Robert J., et al. “SCOPES: Sparking Curiosity through Open-Source Platforms in Education and Science.” <i>Frontiers in Education</i>, vol. 5, 48, Frontiers Media, 2020, doi:<a href=\"https://doi.org/10.3389/feduc.2020.00048\">10.3389/feduc.2020.00048</a>."},"has_accepted_license":"1","title":"SCOPES: Sparking curiosity through Open-Source platforms in education and science","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"},{"_id":"EM-Fac"}],"oa_version":"Published Version","scopus_import":"1","article_type":"original","article_processing_charge":"No","corr_author":"1","_id":"7814","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Beattie","orcid":"0000-0002-8483-8753","full_name":"Beattie, Robert J","id":"2E26DF60-F248-11E8-B48F-1D18A9856A87","first_name":"Robert J"},{"first_name":"Simon","orcid":"0000-0003-2279-1061","full_name":"Hippenmeyer, Simon","last_name":"Hippenmeyer","id":"37B36620-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Florian","id":"48EA0138-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7462-0048","full_name":"Pauler, Florian","last_name":"Pauler"}],"type":"journal_article","day":"08","status":"public","month":"05","quality_controlled":"1","publisher":"Frontiers Media","article_number":"48","publication_identifier":{"issn":["2504-284X"]},"file_date_updated":"2020-07-14T12:48:03Z","file":[{"relation":"main_file","checksum":"a24ec24e38d843341ae620ec76c53688","file_id":"7818","content_type":"application/pdf","date_created":"2020-05-11T11:34:08Z","creator":"dernst","file_name":"2020_FrontiersEduc_Beattie.pdf","file_size":1402146,"date_updated":"2020-07-14T12:48:03Z","access_level":"open_access"}],"intvolume":"         5","publication":"Frontiers in Education","publication_status":"published","department":[{"_id":"SiHi"}],"ec_funded":1,"abstract":[{"lang":"eng","text":"Scientific research is to date largely restricted to wealthy laboratories in developed nations due to the necessity of complex and expensive equipment. This inequality limits the capacity of science to be used as a diplomatic channel. Maker movements use open-source technologies including additive manufacturing (3D printing) and laser cutting, together with low-cost computers for developing novel products. This movement is setting the groundwork for a revolution, allowing scientific equipment to be sourced at a fraction of the cost and has the potential to increase the availability of equipment for scientists around the world. Science education is increasingly recognized as another channel for science diplomacy. In this perspective, we introduce the idea that the Maker movement and open-source technologies have the potential to revolutionize science, technology, engineering and mathematics (STEM) education worldwide. We present an open-source STEM didactic tool called SCOPES (Sparking Curiosity through Open-source Platforms in Education and Science). SCOPES is self-contained, independent of local resources, and cost-effective. SCOPES can be adapted to communicate complex subjects from genetics to neurobiology, perform real-world biological experiments and explore digitized scientific samples. We envision such platforms will enhance science diplomacy by providing a means for scientists to share their findings with classrooms and for educators to incorporate didactic concepts into STEM lessons. By providing students the opportunity to design, perform, and share scientific experiments, students also experience firsthand the benefits of a multinational scientific community. We provide instructions on how to build and use SCOPES on our webpage: http://scopeseducation.org."}],"doi":"10.3389/feduc.2020.00048","ddc":["570"],"project":[{"call_identifier":"FWF","grant_number":"M02416","_id":"264E56E2-B435-11E9-9278-68D0E5697425","name":"Molecular Mechanisms Regulating Gliogenesis in the Neocortex"},{"name":"Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development","_id":"260018B0-B435-11E9-9278-68D0E5697425","grant_number":"725780","call_identifier":"H2020"}],"date_published":"2020-05-08T00:00:00Z","volume":5,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2024-10-22T10:46:38Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2020","date_created":"2020-05-11T08:18:48Z"},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":59,"date_updated":"2023-09-05T16:02:53Z","ddc":["540","546"],"date_published":"2020-09-07T00:00:00Z","date_created":"2020-05-14T21:00:30Z","year":"2020","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","file":[{"creator":"dernst","file_name":"2020_AngChemieINT_Buchal.pdf","file_size":1966184,"date_updated":"2020-09-17T08:57:16Z","access_level":"open_access","relation":"main_file","checksum":"7b6c2fc20e9b0ff4353352f7a7004e2d","file_id":"8400","success":1,"content_type":"application/pdf","date_created":"2020-09-17T08:57:16Z"}],"intvolume":"        59","publication":"Angewandte Chemie International Edition","file_date_updated":"2020-09-17T08:57:16Z","doi":"10.1002/anie.202005378","abstract":[{"lang":"eng","text":"Water-in-salt electrolytes based on highly concentrated bis(trifluoromethyl)sulfonimide (TFSI) promise aqueous electrolytes with stabilities nearing 3 V. However, especially with an electrode approaching the cathodic (reductive) stability, cycling stability is insufficient. While stability critically relies on a solid electrolyte interphase (SEI), the mechanism behind the cathodic stability limit remains unclear. Here, we reveal two distinct reduction potentials for the chemical environments of 'free' and 'bound' water and that both contribute to SEI formation. Free-water is reduced ~1V above bound water in a hydrogen evolution reaction (HER) and responsible for SEI formation via reactive intermediates of the HER; concurrent LiTFSI precipitation/dissolution establishes a dynamic interface. The free-water population emerges, therefore, as the handle to extend the cathodic limit of aqueous electrolytes and the battery cycling stability. "}],"external_id":{"pmid":["32390281"],"isi":["000541488700001"]},"department":[{"_id":"StFr"}],"publication_status":"published","author":[{"last_name":"Bouchal","full_name":"Bouchal, Roza","first_name":"Roza"},{"first_name":"Zhujie","full_name":"Li, Zhujie","last_name":"Li"},{"full_name":"Bongu, Chandra","last_name":"Bongu","first_name":"Chandra"},{"full_name":"Le Vot, Steven","last_name":"Le Vot","first_name":"Steven"},{"full_name":"Berthelot, Romain","last_name":"Berthelot","first_name":"Romain"},{"full_name":"Rotenberg, Benjamin","last_name":"Rotenberg","first_name":"Benjamin"},{"last_name":"Favier","full_name":"Favier, Fréderic","first_name":"Fréderic"},{"first_name":"Stefan Alexander","id":"A8CA28E6-CE23-11E9-AD2D-EC27E6697425","full_name":"Freunberger, Stefan Alexander","orcid":"0000-0003-2902-5319","last_name":"Freunberger"},{"first_name":"Mathieu","full_name":"Salanne, Mathieu","last_name":"Salanne"},{"full_name":"Fontaine, Olivier","last_name":"Fontaine","first_name":"Olivier"}],"language":[{"iso":"eng"}],"oa":1,"_id":"7847","issue":"37","article_processing_charge":"No","article_type":"original","publisher":"Wiley","publication_identifier":{"eissn":["1521-3773"],"issn":["1433-7851"]},"month":"09","quality_controlled":"1","status":"public","page":"15913-1591","type":"journal_article","day":"07","has_accepted_license":"1","citation":{"short":"R. Bouchal, Z. Li, C. Bongu, S. Le Vot, R. Berthelot, B. Rotenberg, F. Favier, S.A. Freunberger, M. Salanne, O. Fontaine, Angewandte Chemie International Edition 59 (2020) 15913–1591.","ieee":"R. Bouchal <i>et al.</i>, “Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte,” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 37. Wiley, pp. 15913–1591, 2020.","ama":"Bouchal R, Li Z, Bongu C, et al. Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. <i>Angewandte Chemie International Edition</i>. 2020;59(37):15913-1591. doi:<a href=\"https://doi.org/10.1002/anie.202005378\">10.1002/anie.202005378</a>","ista":"Bouchal R, Li Z, Bongu C, Le Vot S, Berthelot R, Rotenberg B, Favier F, Freunberger SA, Salanne M, Fontaine O. 2020. Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. Angewandte Chemie International Edition. 59(37), 15913–1591.","apa":"Bouchal, R., Li, Z., Bongu, C., Le Vot, S., Berthelot, R., Rotenberg, B., … Fontaine, O. (2020). Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte. <i>Angewandte Chemie International Edition</i>. Wiley. <a href=\"https://doi.org/10.1002/anie.202005378\">https://doi.org/10.1002/anie.202005378</a>","chicago":"Bouchal, Roza, Zhujie Li, Chandra Bongu, Steven Le Vot, Romain Berthelot, Benjamin Rotenberg, Fréderic Favier, Stefan Alexander Freunberger, Mathieu Salanne, and Olivier Fontaine. “Competitive Salt Precipitation/Dissolution during Free‐water Reduction in Water‐in‐salt Electrolyte.” <i>Angewandte Chemie International Edition</i>. Wiley, 2020. <a href=\"https://doi.org/10.1002/anie.202005378\">https://doi.org/10.1002/anie.202005378</a>.","mla":"Bouchal, Roza, et al. “Competitive Salt Precipitation/Dissolution during Free‐water Reduction in Water‐in‐salt Electrolyte.” <i>Angewandte Chemie International Edition</i>, vol. 59, no. 37, Wiley, 2020, pp. 15913–1591, doi:<a href=\"https://doi.org/10.1002/anie.202005378\">10.1002/anie.202005378</a>."},"pmid":1,"isi":1,"scopus_import":"1","oa_version":"Published Version","title":"Competitive salt precipitation/dissolution during free‐water reduction in water‐in‐salt electrolyte"},{"external_id":{"pmid":["33195442"]},"department":[{"_id":"JuFi"}],"publication_status":"published","doi":"10.1007/s41808-020-00068-8","abstract":[{"text":"In this paper, we establish convergence to equilibrium for a drift–diffusion–recombination system modelling the charge transport within certain semiconductor devices. More precisely, we consider a two-level system for electrons and holes which is augmented by an intermediate energy level for electrons in so-called trapped states. The recombination dynamics use the mass action principle by taking into account this additional trap level. The main part of the paper is concerned with the derivation of an entropy–entropy production inequality, which entails exponential convergence to the equilibrium via the so-called entropy method. The novelty of our approach lies in the fact that the entropy method is applied uniformly in a fast-reaction parameter which governs the lifetime of electrons on the trap level. Thus, the resulting decay estimate for the densities of electrons and holes extends to the corresponding quasi-steady-state approximation.","lang":"eng"}],"file_date_updated":"2020-11-25T08:59:59Z","file":[{"checksum":"6bc6832caacddceee1471291e93dcf1d","file_id":"8802","relation":"main_file","date_created":"2020-11-25T08:59:59Z","content_type":"application/pdf","success":1,"creator":"dernst","access_level":"open_access","file_size":8408694,"date_updated":"2020-11-25T08:59:59Z","file_name":"2020_JourEllipticParabEquat_Fellner.pdf"}],"intvolume":"         6","publication":"Journal of Elliptic and Parabolic Equations","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-05-17T22:00:45Z","year":"2020","ddc":["510"],"project":[{"call_identifier":"FWF","_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","name":"FWF Open Access Fund"}],"date_published":"2020-12-01T00:00:00Z","volume":6,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2025-07-17T08:12:24Z","title":"Uniform convergence to equilibrium for a family of drift–diffusion models with trap-assisted recombination and the limiting Shockley–Read–Hall model","oa_version":"Published Version","scopus_import":"1","acknowledgement":"Open access funding provided by Austrian Science Fund (FWF). The second author has been supported by the International Research Training Group IGDK 1754 “Optimization and Numerical Analysis for Partial Differential Equations with Nonsmooth Structures”, funded by the German Research Council (DFG) and the Austrian Science Fund (FWF) under grant number [W 1244-N18].","pmid":1,"has_accepted_license":"1","citation":{"ieee":"K. Fellner and M. Kniely, “Uniform convergence to equilibrium for a family of drift–diffusion models with trap-assisted recombination and the limiting Shockley–Read–Hall model,” <i>Journal of Elliptic and Parabolic Equations</i>, vol. 6. Springer Nature, pp. 529–598, 2020.","short":"K. Fellner, M. Kniely, Journal of Elliptic and Parabolic Equations 6 (2020) 529–598.","ama":"Fellner K, Kniely M. Uniform convergence to equilibrium for a family of drift–diffusion models with trap-assisted recombination and the limiting Shockley–Read–Hall model. <i>Journal of Elliptic and Parabolic Equations</i>. 2020;6:529-598. doi:<a href=\"https://doi.org/10.1007/s41808-020-00068-8\">10.1007/s41808-020-00068-8</a>","apa":"Fellner, K., &#38; Kniely, M. (2020). Uniform convergence to equilibrium for a family of drift–diffusion models with trap-assisted recombination and the limiting Shockley–Read–Hall model. <i>Journal of Elliptic and Parabolic Equations</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s41808-020-00068-8\">https://doi.org/10.1007/s41808-020-00068-8</a>","ista":"Fellner K, Kniely M. 2020. Uniform convergence to equilibrium for a family of drift–diffusion models with trap-assisted recombination and the limiting Shockley–Read–Hall model. Journal of Elliptic and Parabolic Equations. 6, 529–598.","chicago":"Fellner, Klemens, and Michael Kniely. “Uniform Convergence to Equilibrium for a Family of Drift–Diffusion Models with Trap-Assisted Recombination and the Limiting Shockley–Read–Hall Model.” <i>Journal of Elliptic and Parabolic Equations</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s41808-020-00068-8\">https://doi.org/10.1007/s41808-020-00068-8</a>.","mla":"Fellner, Klemens, and Michael Kniely. “Uniform Convergence to Equilibrium for a Family of Drift–Diffusion Models with Trap-Assisted Recombination and the Limiting Shockley–Read–Hall Model.” <i>Journal of Elliptic and Parabolic Equations</i>, vol. 6, Springer Nature, 2020, pp. 529–98, doi:<a href=\"https://doi.org/10.1007/s41808-020-00068-8\">10.1007/s41808-020-00068-8</a>."},"page":"529-598","status":"public","type":"journal_article","day":"01","publication_identifier":{"issn":["2296-9020"],"eissn":["2296-9039"]},"publisher":"Springer Nature","quality_controlled":"1","month":"12","corr_author":"1","_id":"7866","article_type":"original","article_processing_charge":"No","author":[{"full_name":"Fellner, Klemens","last_name":"Fellner","first_name":"Klemens"},{"first_name":"Michael","last_name":"Kniely","full_name":"Kniely, Michael","orcid":"0000-0001-5645-4333","id":"2CA2C08C-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"oa":1},{"date_published":"2020-06-01T00:00:00Z","project":[{"grant_number":"281556","_id":"25A603A2-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Cytoskeletal force generation and force transduction of migrating leukocytes"},{"name":"Cellular Navigation Along Spatial Gradients","_id":"25FE9508-B435-11E9-9278-68D0E5697425","grant_number":"724373","call_identifier":"H2020"},{"name":"Mechanical adaptation of lamellipodial actin","grant_number":"P29911","_id":"26018E70-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"},{"call_identifier":"FWF","_id":"252C3B08-B435-11E9-9278-68D0E5697425","grant_number":"W1250-B20","name":"Nano-Analytics of Cellular Systems"},{"name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","call_identifier":"FP7"},{"name":"Molecular and system level view of immune cell migration","_id":"25A48D24-B435-11E9-9278-68D0E5697425","grant_number":"ALTF 1396-2014"}],"ddc":["570"],"date_updated":"2025-04-14T13:10:03Z","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"volume":219,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","year":"2020","date_created":"2020-05-24T22:00:56Z","file_date_updated":"2020-11-24T13:25:13Z","publication":"The Journal of Cell Biology","intvolume":"       219","file":[{"file_id":"8801","checksum":"cb0b9c77842ae1214caade7b77e4d82d","relation":"main_file","date_created":"2020-11-24T13:25:13Z","content_type":"application/pdf","success":1,"creator":"dernst","access_level":"open_access","date_updated":"2020-11-24T13:25:13Z","file_name":"2020_JCellBiol_Kopf.pdf","file_size":7536712}],"publication_status":"published","department":[{"_id":"MiSi"},{"_id":"Bio"},{"_id":"NanoFab"}],"external_id":{"isi":["000538141100020"],"pmid":["32379884"]},"ec_funded":1,"abstract":[{"lang":"eng","text":"Cells navigating through complex tissues face a fundamental challenge: while multiple protrusions explore different paths, the cell needs to avoid entanglement. How a cell surveys and then corrects its own shape is poorly understood. Here, we demonstrate that spatially distinct microtubule dynamics regulate amoeboid cell migration by locally promoting the retraction of protrusions. In migrating dendritic cells, local microtubule depolymerization within protrusions remote from the microtubule organizing center triggers actomyosin contractility controlled by RhoA and its exchange factor Lfc. Depletion of Lfc leads to aberrant myosin localization, thereby causing two effects that rate-limit locomotion: (1) impaired cell edge coordination during path finding and (2) defective adhesion resolution. Compromised shape control is particularly hindering in geometrically complex microenvironments, where it leads to entanglement and ultimately fragmentation of the cell body. We thus demonstrate that microtubules can act as a proprioceptive device: they sense cell shape and control actomyosin retraction to sustain cellular coherence."}],"doi":"10.1083/jcb.201907154","article_type":"original","article_processing_charge":"No","_id":"7875","issue":"6","corr_author":"1","language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Aglaja","id":"31DAC7B6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2187-6656","full_name":"Kopf, Aglaja","last_name":"Kopf"},{"orcid":"0000-0003-2856-3369","full_name":"Renkawitz, Jörg","last_name":"Renkawitz","id":"3F0587C8-F248-11E8-B48F-1D18A9856A87","first_name":"Jörg"},{"full_name":"Hauschild, Robert","orcid":"0000-0001-9843-3522","last_name":"Hauschild","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","first_name":"Robert"},{"first_name":"Irute","full_name":"Girkontaite, Irute","last_name":"Girkontaite"},{"full_name":"Tedford, Kerry","last_name":"Tedford","first_name":"Kerry"},{"last_name":"Merrin","full_name":"Merrin, Jack","orcid":"0000-0001-5145-4609","id":"4515C308-F248-11E8-B48F-1D18A9856A87","first_name":"Jack"},{"full_name":"Thorn-Seshold, Oliver","last_name":"Thorn-Seshold","first_name":"Oliver"},{"first_name":"Dirk","last_name":"Trauner","full_name":"Trauner, Dirk","id":"E8F27F48-3EBA-11E9-92A1-B709E6697425"},{"first_name":"Hans","last_name":"Häcker","full_name":"Häcker, Hans"},{"last_name":"Fischer","full_name":"Fischer, Klaus Dieter","first_name":"Klaus Dieter"},{"full_name":"Kiermaier, Eva","orcid":"0000-0001-6165-5738","last_name":"Kiermaier","id":"3EB04B78-F248-11E8-B48F-1D18A9856A87","first_name":"Eva"},{"last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","first_name":"Michael K"}],"day":"01","type":"journal_article","status":"public","quality_controlled":"1","month":"06","publisher":"Rockefeller University Press","article_number":"e201907154","publication_identifier":{"eissn":["1540-8140"]},"pmid":1,"citation":{"chicago":"Kopf, Aglaja, Jörg Renkawitz, Robert Hauschild, Irute Girkontaite, Kerry Tedford, Jack Merrin, Oliver Thorn-Seshold, et al. “Microtubules Control Cellular Shape and Coherence in Amoeboid Migrating Cells.” <i>The Journal of Cell Biology</i>. Rockefeller University Press, 2020. <a href=\"https://doi.org/10.1083/jcb.201907154\">https://doi.org/10.1083/jcb.201907154</a>.","mla":"Kopf, Aglaja, et al. “Microtubules Control Cellular Shape and Coherence in Amoeboid Migrating Cells.” <i>The Journal of Cell Biology</i>, vol. 219, no. 6, e201907154, Rockefeller University Press, 2020, doi:<a href=\"https://doi.org/10.1083/jcb.201907154\">10.1083/jcb.201907154</a>.","apa":"Kopf, A., Renkawitz, J., Hauschild, R., Girkontaite, I., Tedford, K., Merrin, J., … Sixt, M. K. (2020). Microtubules control cellular shape and coherence in amoeboid migrating cells. <i>The Journal of Cell Biology</i>. Rockefeller University Press. <a href=\"https://doi.org/10.1083/jcb.201907154\">https://doi.org/10.1083/jcb.201907154</a>","ista":"Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E, Sixt MK. 2020. Microtubules control cellular shape and coherence in amoeboid migrating cells. The Journal of Cell Biology. 219(6), e201907154.","short":"A. Kopf, J. Renkawitz, R. Hauschild, I. Girkontaite, K. Tedford, J. Merrin, O. Thorn-Seshold, D. Trauner, H. Häcker, K.D. Fischer, E. Kiermaier, M.K. Sixt, The Journal of Cell Biology 219 (2020).","ieee":"A. Kopf <i>et al.</i>, “Microtubules control cellular shape and coherence in amoeboid migrating cells,” <i>The Journal of Cell Biology</i>, vol. 219, no. 6. Rockefeller University Press, 2020.","ama":"Kopf A, Renkawitz J, Hauschild R, et al. Microtubules control cellular shape and coherence in amoeboid migrating cells. <i>The Journal of Cell Biology</i>. 2020;219(6). doi:<a href=\"https://doi.org/10.1083/jcb.201907154\">10.1083/jcb.201907154</a>"},"has_accepted_license":"1","title":"Microtubules control cellular shape and coherence in amoeboid migrating cells","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"},{"_id":"PreCl"}],"scopus_import":"1","oa_version":"Published Version","acknowledgement":"The authors thank the Scientific Service Units (Life Sciences, Bioimaging, Preclinical) of the Institute of Science and Technology Austria for excellent support. This work was funded by the European Research Council (ERC StG 281556 and CoG 724373), two grants from the Austrian\r\nScience Fund (FWF; P29911 and DK Nanocell W1250-B20 to M. Sixt) and by the German Research Foundation (DFG SFB1032 project B09) to O. Thorn-Seshold and D. Trauner. J. Renkawitz was supported by ISTFELLOW funding from the People Program (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under the Research Executive Agency grant agreement (291734) and a European Molecular Biology Organization long-term fellowship (ALTF 1396-2014) co-funded by the European Commission (LTFCOFUND2013, GA-2013-609409), E. Kiermaier by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy—EXC 2151—390873048, and H. Hacker by the American Lebanese Syrian Associated ¨Charities. K.-D. Fischer was supported by the Analysis, Imaging and Modelling of Neuronal and Inflammatory Processes graduate school funded by the Ministry of Economics, Science, and Digitisation of the State Saxony-Anhalt and by the European Funds for Social and Regional Development.","isi":1},{"publication":"Immunity","intvolume":"        52","publication_status":"published","external_id":{"isi":["000535371100002"],"pmid":["32433942"]},"department":[{"_id":"MiSi"}],"abstract":[{"text":"In contrast to lymph nodes, the lymphoid regions of the spleen—the white pulp—are located deep within the organ, yielding the trafficking paths of T cells in the white pulp largely invisible. In an intravital microscopy tour de force reported in this issue of Immunity, Chauveau et al. show that T cells perform unidirectional, perivascular migration through the enigmatic marginal zone bridging channels. ","lang":"eng"}],"doi":"10.1016/j.immuni.2020.04.020","ddc":["570"],"date_published":"2020-05-19T00:00:00Z","volume":52,"date_updated":"2026-06-18T19:27:52Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","year":"2020","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1016/j.immuni.2020.04.020"}],"date_created":"2020-05-24T22:00:57Z","pmid":1,"citation":{"ista":"Sixt MK, Lämmermann T. 2020. T cells: Bridge-and-channel commute to the white pulp. Immunity. 52(5), 721–723.","apa":"Sixt, M. K., &#38; Lämmermann, T. (2020). T cells: Bridge-and-channel commute to the white pulp. <i>Immunity</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.immuni.2020.04.020\">https://doi.org/10.1016/j.immuni.2020.04.020</a>","ieee":"M. K. Sixt and T. Lämmermann, “T cells: Bridge-and-channel commute to the white pulp,” <i>Immunity</i>, vol. 52, no. 5. Elsevier, pp. 721–723, 2020.","ama":"Sixt MK, Lämmermann T. T cells: Bridge-and-channel commute to the white pulp. <i>Immunity</i>. 2020;52(5):721-723. doi:<a href=\"https://doi.org/10.1016/j.immuni.2020.04.020\">10.1016/j.immuni.2020.04.020</a>","short":"M.K. Sixt, T. Lämmermann, Immunity 52 (2020) 721–723.","chicago":"Sixt, Michael K, and Tim Lämmermann. “T Cells: Bridge-and-Channel Commute to the White Pulp.” <i>Immunity</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.immuni.2020.04.020\">https://doi.org/10.1016/j.immuni.2020.04.020</a>.","mla":"Sixt, Michael K., and Tim Lämmermann. “T Cells: Bridge-and-Channel Commute to the White Pulp.” <i>Immunity</i>, vol. 52, no. 5, Elsevier, 2020, pp. 721–23, doi:<a href=\"https://doi.org/10.1016/j.immuni.2020.04.020\">10.1016/j.immuni.2020.04.020</a>."},"title":"T cells: Bridge-and-channel commute to the white pulp","scopus_import":"1","oa_version":"Published Version","OA_type":"free access","isi":1,"article_processing_charge":"No","article_type":"original","issue":"5","_id":"7876","language":[{"iso":"eng"}],"oa":1,"author":[{"last_name":"Sixt","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","first_name":"Michael K"},{"first_name":"Tim","last_name":"Lämmermann","full_name":"Lämmermann, Tim"}],"type":"journal_article","day":"19","status":"public","page":"721-723","OA_place":"publisher","month":"05","quality_controlled":"1","publication_identifier":{"issn":["1074-7613"],"eissn":["1097-4180"]},"publisher":"Elsevier"},{"citation":{"chicago":"Parenti, Ilaria, Farah Diab, Sara Ruiz Gil, Eskeatnaf Mulugeta, Valentina Casa, Riccardo Berutti, Rutger W.W. Brouwer, et al. “MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome.” <i>Cell Reports</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.celrep.2020.107647\">https://doi.org/10.1016/j.celrep.2020.107647</a>.","mla":"Parenti, Ilaria, et al. “MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome.” <i>Cell Reports</i>, vol. 31, no. 7, 107647, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.celrep.2020.107647\">10.1016/j.celrep.2020.107647</a>.","apa":"Parenti, I., Diab, F., Gil, S. R., Mulugeta, E., Casa, V., Berutti, R., … Wendt, K. S. (2020). MAU2 and NIPBL variants impair the heterodimerization of the cohesin loader subunits and cause Cornelia de Lange syndrome. <i>Cell Reports</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.celrep.2020.107647\">https://doi.org/10.1016/j.celrep.2020.107647</a>","ista":"Parenti I, Diab F, Gil SR, Mulugeta E, Casa V, Berutti R, Brouwer RWW, Dupé V, Eckhold J, Graf E, Puisac B, Ramos F, Schwarzmayr T, Gines MM, Van Staveren T, Van Ijcken WFJ, Strom TM, Pié J, Watrin E, Kaiser FJ, Wendt KS. 2020. MAU2 and NIPBL variants impair the heterodimerization of the cohesin loader subunits and cause Cornelia de Lange syndrome. Cell Reports. 31(7), 107647.","short":"I. Parenti, F. Diab, S.R. Gil, E. Mulugeta, V. Casa, R. Berutti, R.W.W. Brouwer, V. Dupé, J. Eckhold, E. Graf, B. Puisac, F. Ramos, T. Schwarzmayr, M.M. Gines, T. Van Staveren, W.F.J. Van Ijcken, T.M. Strom, J. Pié, E. Watrin, F.J. Kaiser, K.S. Wendt, Cell Reports 31 (2020).","ama":"Parenti I, Diab F, Gil SR, et al. MAU2 and NIPBL variants impair the heterodimerization of the cohesin loader subunits and cause Cornelia de Lange syndrome. <i>Cell Reports</i>. 2020;31(7). doi:<a href=\"https://doi.org/10.1016/j.celrep.2020.107647\">10.1016/j.celrep.2020.107647</a>","ieee":"I. Parenti <i>et al.</i>, “MAU2 and NIPBL variants impair the heterodimerization of the cohesin loader subunits and cause Cornelia de Lange syndrome,” <i>Cell Reports</i>, vol. 31, no. 7. Elsevier, 2020."},"has_accepted_license":"1","oa_version":"Published Version","scopus_import":"1","isi":1,"title":"MAU2 and NIPBL variants impair the heterodimerization of the cohesin loader subunits and cause Cornelia de Lange syndrome","oa":1,"language":[{"iso":"eng"}],"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","author":[{"first_name":"Ilaria","id":"D93538B0-5B71-11E9-AC62-02EBE5697425","last_name":"Parenti","full_name":"Parenti, Ilaria"},{"first_name":"Farah","last_name":"Diab","full_name":"Diab, Farah"},{"first_name":"Sara Ruiz","last_name":"Gil","full_name":"Gil, Sara Ruiz"},{"first_name":"Eskeatnaf","last_name":"Mulugeta","full_name":"Mulugeta, Eskeatnaf"},{"full_name":"Casa, Valentina","last_name":"Casa","first_name":"Valentina"},{"first_name":"Riccardo","last_name":"Berutti","full_name":"Berutti, Riccardo"},{"full_name":"Brouwer, Rutger W.W.","last_name":"Brouwer","first_name":"Rutger W.W."},{"first_name":"Valerie","full_name":"Dupé, Valerie","last_name":"Dupé"},{"first_name":"Juliane","last_name":"Eckhold","full_name":"Eckhold, Juliane"},{"full_name":"Graf, Elisabeth","last_name":"Graf","first_name":"Elisabeth"},{"full_name":"Puisac, Beatriz","last_name":"Puisac","first_name":"Beatriz"},{"first_name":"Feliciano","full_name":"Ramos, Feliciano","last_name":"Ramos"},{"first_name":"Thomas","last_name":"Schwarzmayr","full_name":"Schwarzmayr, Thomas"},{"last_name":"Gines","full_name":"Gines, Macarena Moronta","first_name":"Macarena Moronta"},{"full_name":"Van Staveren, Thomas","last_name":"Van Staveren","first_name":"Thomas"},{"last_name":"Van Ijcken","full_name":"Van Ijcken, Wilfred F.J.","first_name":"Wilfred F.J."},{"last_name":"Strom","full_name":"Strom, Tim M.","first_name":"Tim M."},{"full_name":"Pié, Juan","last_name":"Pié","first_name":"Juan"},{"last_name":"Watrin","full_name":"Watrin, Erwan","first_name":"Erwan"},{"first_name":"Frank J.","full_name":"Kaiser, Frank J.","last_name":"Kaiser"},{"last_name":"Wendt","full_name":"Wendt, Kerstin S.","first_name":"Kerstin S."}],"article_processing_charge":"No","article_type":"original","_id":"7877","issue":"7","quality_controlled":"1","month":"05","article_number":"107647","publisher":"Elsevier","publication_identifier":{"eissn":["2211-1247"]},"day":"19","type":"journal_article","status":"public","publication":"Cell Reports","file":[{"file_name":"2020_CellReports_Parenti.pdf","file_size":4695682,"date_updated":"2020-07-14T12:48:04Z","access_level":"open_access","creator":"dernst","content_type":"application/pdf","date_created":"2020-05-26T11:05:01Z","relation":"main_file","checksum":"64d8f7467731ee5c166b10b939b8310b","file_id":"7892"}],"intvolume":"        31","file_date_updated":"2020-07-14T12:48:04Z","abstract":[{"text":"The NIPBL/MAU2 heterodimer loads cohesin onto chromatin. Mutations inNIPBLaccount for most cases ofthe rare developmental disorder Cornelia de Lange syndrome (CdLS). Here we report aMAU2 variant causing CdLS, a deletion of seven amino acids that impairs the interaction between MAU2 and the NIPBL N terminus.Investigating this interaction, we discovered that MAU2 and the NIPBL N terminus are largely dispensable fornormal cohesin and NIPBL function in cells with a NIPBL early truncating mutation. Despite a predicted fataloutcome of an out-of-frame single nucleotide duplication inNIPBL, engineered in two different cell lines,alternative translation initiation yields a form of NIPBL missing N-terminal residues. This form cannot interactwith MAU2, but binds DNA and mediates cohesin loading. Altogether, our work reveals that cohesin loading can occur independently of functional NIPBL/MAU2 complexes and highlights a novel mechanism protectiveagainst out-of-frame mutations that is potentially relevant for other genetic conditions.","lang":"eng"}],"doi":"10.1016/j.celrep.2020.107647","publication_status":"published","department":[{"_id":"GaNo"}],"external_id":{"isi":["000535655200005"]},"date_updated":"2026-04-02T14:28:04Z","tmp":{"name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode"},"volume":31,"date_published":"2020-05-19T00:00:00Z","ddc":["570"],"year":"2020","date_created":"2020-05-24T22:00:57Z","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd"},{"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","year":"2020","date_created":"2020-05-24T22:00:58Z","date_published":"2020-05-13T00:00:00Z","ddc":["570"],"date_updated":"2026-04-02T14:28:17Z","volume":9,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"publication_status":"published","department":[{"_id":"RySh"}],"external_id":{"pmid":["32401196"],"isi":["000535191600001"]},"abstract":[{"text":"Type 1 metabotropic glutamate receptors (mGluR1s) are key elements in neuronal signaling. While their function is well documented in slices, requirements for their activation in vivo are poorly understood. We examine this question in adult mice in vivo using 2-photon imaging of cerebellar molecular layer interneurons (MLIs) expressing GCaMP. In anesthetized mice, parallel fiber activation evokes beam-like Cai rises in postsynaptic MLIs which depend on co-activation of mGluR1s and ionotropic glutamate receptors (iGluRs). In awake mice, blocking mGluR1 decreases Cai rises associated with locomotion. In vitro studies and freeze-fracture electron microscopy show that the iGluR-mGluR1 interaction is synergistic and favored by close association of the two classes of receptors. Altogether our results suggest that mGluR1s, acting in synergy with iGluRs, potently contribute to processing cerebellar neuronal signaling under physiological conditions.","lang":"eng"}],"doi":"10.7554/eLife.56839","file_date_updated":"2020-07-14T12:48:04Z","intvolume":"         9","file":[{"relation":"main_file","file_id":"7891","checksum":"8ea99bb6660cc407dbdb00c173b01683","content_type":"application/pdf","date_created":"2020-05-26T09:34:54Z","creator":"dernst","file_size":4832050,"date_updated":"2020-07-14T12:48:04Z","file_name":"2020_eLife_Bao.pdf","access_level":"open_access"}],"publication":"eLife","day":"13","type":"journal_article","status":"public","month":"05","quality_controlled":"1","publication_identifier":{"eissn":["2050-084X"]},"publisher":"eLife Sciences Publications","article_number":"e56839","article_processing_charge":"No","article_type":"original","_id":"7878","oa":1,"language":[{"iso":"eng"}],"author":[{"full_name":"Bao, Jin","last_name":"Bao","first_name":"Jin"},{"full_name":"Graupner, Michael","last_name":"Graupner","first_name":"Michael"},{"last_name":"Astorga","full_name":"Astorga, Guadalupe","first_name":"Guadalupe"},{"full_name":"Collin, Thibault","last_name":"Collin","first_name":"Thibault"},{"full_name":"Jalil, Abdelali","last_name":"Jalil","first_name":"Abdelali"},{"full_name":"Indriati, Dwi Wahyu","last_name":"Indriati","first_name":"Dwi Wahyu"},{"first_name":"Jonathan","full_name":"Bradley, Jonathan","last_name":"Bradley"},{"full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","last_name":"Shigemoto","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","first_name":"Ryuichi"},{"first_name":"Isabel","full_name":"Llano, Isabel","last_name":"Llano"}],"title":"Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo","scopus_import":"1","oa_version":"Published Version","isi":1,"pmid":1,"citation":{"ieee":"J. Bao <i>et al.</i>, “Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020.","short":"J. Bao, M. Graupner, G. Astorga, T. Collin, A. Jalil, D.W. Indriati, J. Bradley, R. Shigemoto, I. Llano, ELife 9 (2020).","ama":"Bao J, Graupner M, Astorga G, et al. Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/eLife.56839\">10.7554/eLife.56839</a>","ista":"Bao J, Graupner M, Astorga G, Collin T, Jalil A, Indriati DW, Bradley J, Shigemoto R, Llano I. 2020. Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo. eLife. 9, e56839.","apa":"Bao, J., Graupner, M., Astorga, G., Collin, T., Jalil, A., Indriati, D. W., … Llano, I. (2020). Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.56839\">https://doi.org/10.7554/eLife.56839</a>","mla":"Bao, Jin, et al. “Synergism of Type 1 Metabotropic and Ionotropic Glutamate Receptors in Cerebellar Molecular Layer Interneurons in Vivo.” <i>ELife</i>, vol. 9, e56839, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/eLife.56839\">10.7554/eLife.56839</a>.","chicago":"Bao, Jin, Michael Graupner, Guadalupe Astorga, Thibault Collin, Abdelali Jalil, Dwi Wahyu Indriati, Jonathan Bradley, Ryuichi Shigemoto, and Isabel Llano. “Synergism of Type 1 Metabotropic and Ionotropic Glutamate Receptors in Cerebellar Molecular Layer Interneurons in Vivo.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/eLife.56839\">https://doi.org/10.7554/eLife.56839</a>."},"has_accepted_license":"1"},{"page":"5229-5244","status":"public","day":"17","type":"journal_article","publisher":"ASBMB Publications","publication_identifier":{"issn":["0021-9258"],"eissn":["1083-351X"]},"quality_controlled":"1","month":"04","_id":"7880","issue":"16","article_type":"original","article_processing_charge":"No","author":[{"first_name":"Rita R.","last_name":"Fagan","full_name":"Fagan, Rita R."},{"first_name":"Patrick J.","full_name":"Kearney, Patrick J.","last_name":"Kearney"},{"full_name":"Sweeney, Carolyn G.","last_name":"Sweeney","first_name":"Carolyn G."},{"full_name":"Luethi, Dino","last_name":"Luethi","first_name":"Dino"},{"first_name":"Florianne E","last_name":"Schoot Uiterkamp","full_name":"Schoot Uiterkamp, Florianne E","id":"3526230C-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Klaus","last_name":"Schicker","full_name":"Schicker, Klaus"},{"first_name":"Brian S.","last_name":"Alejandro","full_name":"Alejandro, Brian S."},{"first_name":"Lauren C.","full_name":"O'Connor, Lauren C.","last_name":"O'Connor"},{"first_name":"Harald H.","last_name":"Sitte","full_name":"Sitte, Harald H."},{"last_name":"Melikian","full_name":"Melikian, Haley E.","first_name":"Haley E."}],"oa":1,"language":[{"iso":"eng"}],"title":"Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact","isi":1,"scopus_import":"1","oa_version":"Submitted Version","pmid":1,"citation":{"ieee":"R. R. Fagan <i>et al.</i>, “Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact,” <i>Journal of Biological Chemistry</i>, vol. 295, no. 16. ASBMB Publications, pp. 5229–5244, 2020.","ama":"Fagan RR, Kearney PJ, Sweeney CG, et al. Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. <i>Journal of Biological Chemistry</i>. 2020;295(16):5229-5244. doi:<a href=\"https://doi.org/10.1074/jbc.RA120.012628\">10.1074/jbc.RA120.012628</a>","short":"R.R. Fagan, P.J. Kearney, C.G. Sweeney, D. Luethi, F.E. Schoot Uiterkamp, K. Schicker, B.S. Alejandro, L.C. O’Connor, H.H. Sitte, H.E. Melikian, Journal of Biological Chemistry 295 (2020) 5229–5244.","apa":"Fagan, R. R., Kearney, P. J., Sweeney, C. G., Luethi, D., Schoot Uiterkamp, F. E., Schicker, K., … Melikian, H. E. (2020). Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. <i>Journal of Biological Chemistry</i>. ASBMB Publications. <a href=\"https://doi.org/10.1074/jbc.RA120.012628\">https://doi.org/10.1074/jbc.RA120.012628</a>","ista":"Fagan RR, Kearney PJ, Sweeney CG, Luethi D, Schoot Uiterkamp FE, Schicker K, Alejandro BS, O’Connor LC, Sitte HH, Melikian HE. 2020. Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. Journal of Biological Chemistry. 295(16), 5229–5244.","chicago":"Fagan, Rita R., Patrick J. Kearney, Carolyn G. Sweeney, Dino Luethi, Florianne E Schoot Uiterkamp, Klaus Schicker, Brian S. Alejandro, Lauren C. O’Connor, Harald H. Sitte, and Haley E. Melikian. “Dopamine Transporter Trafficking and Rit2 GTPase: Mechanism of Action and in Vivo Impact.” <i>Journal of Biological Chemistry</i>. ASBMB Publications, 2020. <a href=\"https://doi.org/10.1074/jbc.RA120.012628\">https://doi.org/10.1074/jbc.RA120.012628</a>.","mla":"Fagan, Rita R., et al. “Dopamine Transporter Trafficking and Rit2 GTPase: Mechanism of Action and in Vivo Impact.” <i>Journal of Biological Chemistry</i>, vol. 295, no. 16, ASBMB Publications, 2020, pp. 5229–44, doi:<a href=\"https://doi.org/10.1074/jbc.RA120.012628\">10.1074/jbc.RA120.012628</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-05-24T22:00:59Z","main_file_link":[{"open_access":"1","url":"https://escholarship.umassmed.edu/oapubs/4187"}],"year":"2020","date_published":"2020-04-17T00:00:00Z","date_updated":"2025-07-10T11:54:48Z","volume":295,"department":[{"_id":"SaSi"}],"external_id":{"pmid":["32132171"],"isi":["000530288000006"]},"publication_status":"published","doi":"10.1074/jbc.RA120.012628","abstract":[{"lang":"eng","text":"Following its evoked release, dopamine (DA) signaling is rapidly terminated by presynaptic reuptake, mediated by the cocaine-sensitive DA transporter (DAT). DAT surface availability is dynamically regulated by endocytic trafficking, and direct protein kinase C (PKC) activation acutely diminishes DAT surface expression by accelerating DAT internalization. Previous cell line studies demonstrated that PKC-stimulated DAT endocytosis requires both Ack1 inactivation, which releases a DAT-specific endocytic brake, and the neuronal GTPase, Rit2, which binds DAT. However, it is unknown whether Rit2 is required for PKC-stimulated DAT endocytosis in DAergic terminals or whether there are region- and/or sex-dependent differences in PKC-stimulated DAT trafficking. Moreover, the mechanisms by which Rit2 controls PKC-stimulated DAT endocytosis are unknown. Here, we directly examined these important questions. Ex vivo studies revealed that PKC activation acutely decreased DAT surface expression selectively in ventral, but not dorsal, striatum. AAV-mediated, conditional Rit2 knockdown in DAergic neurons impacted baseline DAT surface:intracellular distribution in DAergic terminals from female ventral, but not dorsal, striatum. Further, Rit2 was required for PKC-stimulated DAT internalization in both male and female ventral striatum. FRET and surface pulldown studies in cell lines revealed that PKC activation drives DAT-Rit2 surface dissociation and that the DAT N terminus is required for both PKC-mediated DAT-Rit2 dissociation and DAT internalization. Finally, we found that Rit2 and Ack1 independently converge on DAT to facilitate PKC-stimulated DAT endocytosis. Together, our data provide greater insight into mechanisms that mediate PKC-regulated DAT internalization and reveal unexpected region-specific differences in PKC-stimulated DAT trafficking in bona fide DAergic terminals. "}],"intvolume":"       295","publication":"Journal of Biological Chemistry"},{"doi":"10.3390/math8040484","abstract":[{"lang":"eng","text":"A few-body cluster is a building block of a many-body system in a gas phase provided the temperature at most is of the order of the binding energy of this cluster. Here we illustrate this statement by considering a system of tubes filled with dipolar distinguishable particles. We calculate the partition function, which determines the probability to find a few-body cluster at a given temperature. The input for our calculations—the energies of few-body clusters—is estimated using the harmonic approximation. We first describe and demonstrate the validity of our numerical procedure. Then we discuss the results featuring melting of the zero-temperature many-body state into a gas of free particles and few-body clusters. For temperature higher than its binding energy threshold, the dimers overwhelmingly dominate the ensemble, where the remaining probability is in free particles. At very high temperatures free (harmonic oscillator trap-bound) particle dominance is eventually reached. This structure evolution appears both for one and two particles in each layer providing crucial information about the behavior of ultracold dipolar gases. The investigation addresses the transition region between few- and many-body physics as a function of temperature using a system of ten dipoles in five tubes."}],"ec_funded":1,"external_id":{"isi":["000531824100024"]},"department":[{"_id":"MiLe"}],"publication_status":"published","intvolume":"         8","publication":"Mathematics","file":[{"relation":"main_file","checksum":"a05a7df724522203d079673a0d4de4bc","file_id":"7887","content_type":"application/pdf","date_created":"2020-05-25T14:42:22Z","creator":"dernst","file_size":990540,"file_name":"2020_Mathematics_Armstrong.pdf","date_updated":"2020-07-14T12:48:04Z","access_level":"open_access"}],"file_date_updated":"2020-07-14T12:48:04Z","date_created":"2020-05-24T22:01:00Z","year":"2020","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","volume":8,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2026-04-02T14:33:47Z","ddc":["510"],"project":[{"name":"ISTplus - Postdoctoral Fellowships","_id":"260C2330-B435-11E9-9278-68D0E5697425","grant_number":"754411","call_identifier":"H2020"}],"date_published":"2020-04-01T00:00:00Z","isi":1,"oa_version":"Published Version","scopus_import":"1","title":"Clusters in separated tubes of tilted dipoles","has_accepted_license":"1","citation":{"ieee":"J. R. Armstrong, A. S. Jensen, A. Volosniev, and N. T. Zinner, “Clusters in separated tubes of tilted dipoles,” <i>Mathematics</i>, vol. 8, no. 4. MDPI, 2020.","short":"J.R. Armstrong, A.S. Jensen, A. Volosniev, N.T. Zinner, Mathematics 8 (2020).","ama":"Armstrong JR, Jensen AS, Volosniev A, Zinner NT. Clusters in separated tubes of tilted dipoles. <i>Mathematics</i>. 2020;8(4). doi:<a href=\"https://doi.org/10.3390/math8040484\">10.3390/math8040484</a>","apa":"Armstrong, J. R., Jensen, A. S., Volosniev, A., &#38; Zinner, N. T. (2020). Clusters in separated tubes of tilted dipoles. <i>Mathematics</i>. MDPI. <a href=\"https://doi.org/10.3390/math8040484\">https://doi.org/10.3390/math8040484</a>","ista":"Armstrong JR, Jensen AS, Volosniev A, Zinner NT. 2020. Clusters in separated tubes of tilted dipoles. Mathematics. 8(4), 484.","mla":"Armstrong, Jeremy R., et al. “Clusters in Separated Tubes of Tilted Dipoles.” <i>Mathematics</i>, vol. 8, no. 4, 484, MDPI, 2020, doi:<a href=\"https://doi.org/10.3390/math8040484\">10.3390/math8040484</a>.","chicago":"Armstrong, Jeremy R., Aksel S. Jensen, Artem Volosniev, and Nikolaj T. Zinner. “Clusters in Separated Tubes of Tilted Dipoles.” <i>Mathematics</i>. MDPI, 2020. <a href=\"https://doi.org/10.3390/math8040484\">https://doi.org/10.3390/math8040484</a>."},"publisher":"MDPI","publication_identifier":{"eissn":["2227-7390"]},"article_number":"484","quality_controlled":"1","month":"04","status":"public","type":"journal_article","day":"01","author":[{"first_name":"Jeremy R.","last_name":"Armstrong","full_name":"Armstrong, Jeremy R."},{"full_name":"Jensen, Aksel S.","last_name":"Jensen","first_name":"Aksel S."},{"first_name":"Artem","last_name":"Volosniev","orcid":"0000-0003-0393-5525","full_name":"Volosniev, Artem","id":"37D278BC-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Zinner, Nikolaj T.","last_name":"Zinner","first_name":"Nikolaj T."}],"language":[{"iso":"eng"}],"oa":1,"_id":"7882","issue":"4","article_type":"original","article_processing_charge":"No"},{"publication":"Journal of Neuroscience","file":[{"content_type":"application/pdf","date_created":"2020-06-02T09:12:16Z","relation":"main_file","file_id":"7912","checksum":"6571607ea9036154b67cc78e848a7f7d","date_updated":"2020-07-14T12:48:05Z","file_name":"2020_JourNeuroscience_Wang.pdf","file_size":3817360,"access_level":"open_access","creator":"dernst"}],"intvolume":"        40","file_date_updated":"2020-07-14T12:48:05Z","doi":"10.1523/JNEUROSCI.2946-19.2020","abstract":[{"lang":"eng","text":"Volatile anesthetics are widely used for surgery, but neuronal mechanisms of anesthesia remain unidentified. At the calyx of Held in brainstem slices from rats of either sex, isoflurane at clinical doses attenuated EPSCs by decreasing the release probability and the number of readily releasable vesicles. In presynaptic recordings of Ca2+ currents and exocytic capacitance changes, isoflurane attenuated exocytosis by inhibiting Ca2+ currents evoked by a short presynaptic depolarization, whereas it inhibited exocytosis evoked by a prolonged depolarization via directly blocking exocytic machinery downstream of Ca2+ influx. Since the length of presynaptic depolarization can simulate the frequency of synaptic inputs, isoflurane anesthesia is likely mediated by distinct dual mechanisms, depending on input frequencies. In simultaneous presynaptic and postsynaptic action potential recordings, isoflurane impaired the fidelity of repetitive spike transmission, more strongly at higher frequencies. Furthermore, in the cerebrum of adult mice, isoflurane inhibited monosynaptic corticocortical spike transmission, preferentially at a higher frequency. We conclude that dual presynaptic mechanisms operate for the anesthetic action of isoflurane, of which direct inhibition of exocytic machinery plays a low-pass filtering role in spike transmission at central excitatory synapses."}],"external_id":{"pmid":["32327530"],"isi":["000535694700004"]},"department":[{"_id":"RySh"}],"publication_status":"published","volume":40,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2025-03-07T08:29:32Z","ddc":["570"],"date_published":"2020-05-20T00:00:00Z","date_created":"2020-05-31T22:00:48Z","year":"2020","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","citation":{"ama":"Wang HY, Eguchi K, Yamashita T, Takahashi T. Frequency-dependent block of excitatory neurotransmission by isoflurane via dual presynaptic mechanisms. <i>Journal of Neuroscience</i>. 2020;40(21):4103-4115. doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.2946-19.2020\">10.1523/JNEUROSCI.2946-19.2020</a>","short":"H.Y. Wang, K. Eguchi, T. Yamashita, T. Takahashi, Journal of Neuroscience 40 (2020) 4103–4115.","ieee":"H. Y. Wang, K. Eguchi, T. Yamashita, and T. Takahashi, “Frequency-dependent block of excitatory neurotransmission by isoflurane via dual presynaptic mechanisms,” <i>Journal of Neuroscience</i>, vol. 40, no. 21. Society for Neuroscience, pp. 4103–4115, 2020.","apa":"Wang, H. Y., Eguchi, K., Yamashita, T., &#38; Takahashi, T. (2020). Frequency-dependent block of excitatory neurotransmission by isoflurane via dual presynaptic mechanisms. <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href=\"https://doi.org/10.1523/JNEUROSCI.2946-19.2020\">https://doi.org/10.1523/JNEUROSCI.2946-19.2020</a>","ista":"Wang HY, Eguchi K, Yamashita T, Takahashi T. 2020. Frequency-dependent block of excitatory neurotransmission by isoflurane via dual presynaptic mechanisms. Journal of Neuroscience. 40(21), 4103–4115.","mla":"Wang, Han Ying, et al. “Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms.” <i>Journal of Neuroscience</i>, vol. 40, no. 21, Society for Neuroscience, 2020, pp. 4103–15, doi:<a href=\"https://doi.org/10.1523/JNEUROSCI.2946-19.2020\">10.1523/JNEUROSCI.2946-19.2020</a>.","chicago":"Wang, Han Ying, Kohgaku Eguchi, Takayuki Yamashita, and Tomoyuki Takahashi. “Frequency-Dependent Block of Excitatory Neurotransmission by Isoflurane via Dual Presynaptic Mechanisms.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2020. <a href=\"https://doi.org/10.1523/JNEUROSCI.2946-19.2020\">https://doi.org/10.1523/JNEUROSCI.2946-19.2020</a>."},"pmid":1,"isi":1,"oa_version":"Published Version","scopus_import":"1","title":"Frequency-dependent block of excitatory neurotransmission by isoflurane via dual presynaptic mechanisms","author":[{"full_name":"Wang, Han Ying","last_name":"Wang","first_name":"Han Ying"},{"orcid":"0000-0002-6170-2546","full_name":"Eguchi, Kohgaku","last_name":"Eguchi","id":"2B7846DC-F248-11E8-B48F-1D18A9856A87","first_name":"Kohgaku"},{"last_name":"Yamashita","full_name":"Yamashita, Takayuki","first_name":"Takayuki"},{"last_name":"Takahashi","full_name":"Takahashi, Tomoyuki","first_name":"Tomoyuki"}],"language":[{"iso":"eng"}],"oa":1,"issue":"21","_id":"7908","article_type":"original","article_processing_charge":"No","publication_identifier":{"eissn":["1529-2401"]},"publisher":"Society for Neuroscience","month":"05","quality_controlled":"1","status":"public","page":"4103-4115","type":"journal_article","day":"20"},{"external_id":{"pmid":["32391788"],"isi":["000537208000001"]},"department":[{"_id":"MiSi"}],"publication_status":"published","doi":"10.7554/eLife.55351","ec_funded":1,"abstract":[{"text":"Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antagonize efficient cell motility. However, we find these proteins to act as positive regulators of migration in different murine cell lines. CRISPR/Cas9-mediated loss of Ena/VASP proteins reduced lamellipodial actin assembly and perturbed lamellipodial architecture, as evidenced by changed network geometry as well as reduction of filament length and number that was accompanied by abnormal Arp2/3 complex and heterodimeric capping protein accumulation. Loss of Ena/VASP function also abolished the formation of microspikes normally embedded in lamellipodia, but not of filopodia capable of emanating without lamellipodia. Ena/VASP-deficiency also impaired integrin-mediated adhesion accompanied by reduced traction forces exerted through these structures. Our data thus uncover novel Ena/VASP functions of these actin polymerases that are fully consistent with their promotion of cell migration.","lang":"eng"}],"file_date_updated":"2020-07-14T12:48:05Z","publication":"eLife","intvolume":"         9","file":[{"creator":"dernst","file_name":"2020_eLife_Damiano_Guercio.pdf","file_size":10535713,"date_updated":"2020-07-14T12:48:05Z","access_level":"open_access","relation":"main_file","checksum":"d33bd4441b9a0195718ce1ba5d2c48a6","file_id":"7914","content_type":"application/pdf","date_created":"2020-06-02T10:35:37Z"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2020-05-31T22:00:49Z","year":"2020","ddc":["570"],"project":[{"_id":"25FE9508-B435-11E9-9278-68D0E5697425","grant_number":"724373","call_identifier":"H2020","name":"Cellular Navigation Along Spatial Gradients"}],"date_published":"2020-05-11T00:00:00Z","volume":9,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2026-04-02T14:32:12Z","title":"Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion","isi":1,"oa_version":"Published Version","scopus_import":"1","pmid":1,"has_accepted_license":"1","citation":{"short":"J. Damiano-Guercio, L. Kurzawa, J. Müller, G.A. Dimchev, M. Schaks, M. Nemethova, T. Pokrant, S. Brühmann, J. Linkner, L. Blanchoin, M.K. Sixt, K. Rottner, J. Faix, ELife 9 (2020).","ieee":"J. Damiano-Guercio <i>et al.</i>, “Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion,” <i>eLife</i>, vol. 9. eLife Sciences Publications, 2020.","ama":"Damiano-Guercio J, Kurzawa L, Müller J, et al. Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. <i>eLife</i>. 2020;9. doi:<a href=\"https://doi.org/10.7554/eLife.55351\">10.7554/eLife.55351</a>","apa":"Damiano-Guercio, J., Kurzawa, L., Müller, J., Dimchev, G. A., Schaks, M., Nemethova, M., … Faix, J. (2020). Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.55351\">https://doi.org/10.7554/eLife.55351</a>","ista":"Damiano-Guercio J, Kurzawa L, Müller J, Dimchev GA, Schaks M, Nemethova M, Pokrant T, Brühmann S, Linkner J, Blanchoin L, Sixt MK, Rottner K, Faix J. 2020. Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. eLife. 9, e55351.","chicago":"Damiano-Guercio, Julia, Laëtitia Kurzawa, Jan Müller, Georgi A Dimchev, Matthias Schaks, Maria Nemethova, Thomas Pokrant, et al. “Loss of Ena/VASP Interferes with Lamellipodium Architecture, Motility and Integrin-Dependent Adhesion.” <i>ELife</i>. eLife Sciences Publications, 2020. <a href=\"https://doi.org/10.7554/eLife.55351\">https://doi.org/10.7554/eLife.55351</a>.","mla":"Damiano-Guercio, Julia, et al. “Loss of Ena/VASP Interferes with Lamellipodium Architecture, Motility and Integrin-Dependent Adhesion.” <i>ELife</i>, vol. 9, e55351, eLife Sciences Publications, 2020, doi:<a href=\"https://doi.org/10.7554/eLife.55351\">10.7554/eLife.55351</a>."},"status":"public","type":"journal_article","day":"11","publisher":"eLife Sciences Publications","article_number":"e55351","publication_identifier":{"eissn":["2050-084X"]},"month":"05","quality_controlled":"1","_id":"7909","article_type":"original","article_processing_charge":"No","author":[{"first_name":"Julia","last_name":"Damiano-Guercio","full_name":"Damiano-Guercio, Julia"},{"full_name":"Kurzawa, Laëtitia","last_name":"Kurzawa","first_name":"Laëtitia"},{"first_name":"Jan","id":"AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D","last_name":"Müller","full_name":"Müller, Jan"},{"first_name":"Georgi A","orcid":"0000-0001-8370-6161","full_name":"Dimchev, Georgi A","last_name":"Dimchev","id":"38C393BE-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Schaks","full_name":"Schaks, Matthias","first_name":"Matthias"},{"first_name":"Maria","id":"34E27F1C-F248-11E8-B48F-1D18A9856A87","last_name":"Nemethova","full_name":"Nemethova, Maria"},{"full_name":"Pokrant, Thomas","last_name":"Pokrant","first_name":"Thomas"},{"full_name":"Brühmann, Stefan","last_name":"Brühmann","first_name":"Stefan"},{"last_name":"Linkner","full_name":"Linkner, Joern","first_name":"Joern"},{"last_name":"Blanchoin","full_name":"Blanchoin, Laurent","first_name":"Laurent"},{"orcid":"0000-0002-6620-9179","full_name":"Sixt, Michael K","last_name":"Sixt","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","first_name":"Michael K"},{"last_name":"Rottner","full_name":"Rottner, Klemens","first_name":"Klemens"},{"last_name":"Faix","full_name":"Faix, Jan","first_name":"Jan"}],"oa":1,"language":[{"iso":"eng"}]},{"external_id":{"isi":["000531171100045"],"arxiv":["1908.03058"],"pmid":["32548249"]},"department":[{"_id":"JoFi"}],"publication_status":"published","doi":"10.1126/sciadv.abb0451","abstract":[{"lang":"eng","text":"Quantum illumination uses entangled signal-idler photon pairs to boost the detection efficiency of low-reflectivity objects in environments with bright thermal noise. Its advantage is particularly evident at low signal powers, a promising feature for applications such as noninvasive biomedical scanning or low-power short-range radar. Here, we experimentally investigate the concept of quantum illumination at microwave frequencies. We generate entangled fields to illuminate a room-temperature object at a distance of 1 m in a free-space detection setup. We implement a digital phase-conjugate receiver based on linear quadrature measurements that outperforms a symmetric classical noise radar in the same conditions, despite the entanglement-breaking signal path. Starting from experimental data, we also simulate the case of perfect idler photon number detection, which results in a quantum advantage compared with the relative classical benchmark. Our results highlight the opportunities and challenges in the way toward a first room-temperature application of microwave quantum circuits."}],"ec_funded":1,"file_date_updated":"2020-07-14T12:48:05Z","intvolume":"         6","file":[{"creator":"dernst","file_name":"2020_ScienceAdvances_Barzanjeh.pdf","date_updated":"2020-07-14T12:48:05Z","file_size":795822,"access_level":"open_access","relation":"main_file","file_id":"7913","checksum":"16fa61cc1951b444ee74c07188cda9da","content_type":"application/pdf","date_created":"2020-06-02T09:18:36Z"}],"publication":"Science Advances","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2020-05-31T22:00:49Z","year":"2020","ddc":["530"],"project":[{"_id":"26336814-B435-11E9-9278-68D0E5697425","grant_number":"758053","call_identifier":"H2020","name":"A Fiber Optic Transceiver for Superconducting Qubits"},{"name":"Quantum readout techniques and technologies","call_identifier":"H2020","grant_number":"862644","_id":"237CBA6C-32DE-11EA-91FC-C7463DDC885E"},{"name":"Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination with cavity Optomechanics","call_identifier":"H2020","grant_number":"707438","_id":"258047B6-B435-11E9-9278-68D0E5697425"},{"call_identifier":"H2020","_id":"257EB838-B435-11E9-9278-68D0E5697425","grant_number":"732894","name":"Hybrid Optomechanical Technologies"},{"name":"QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration of Superconducting Quantum Circuits","_id":"bdb108fd-d553-11ed-ba76-83dc74a9864f","grant_number":"F07105"}],"date_published":"2020-05-06T00:00:00Z","volume":6,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"date_updated":"2026-04-15T06:42:37Z","title":"Microwave quantum illumination using a digital receiver","related_material":{"link":[{"url":"https://ist.ac.at/en/news/scientists-demonstrate-quantum-radar-prototype/","description":"News on IST Homepage","relation":"press_release"}],"record":[{"id":"9001","relation":"later_version","status":"public"}]},"isi":1,"scopus_import":"1","oa_version":"Published Version","pmid":1,"has_accepted_license":"1","citation":{"mla":"Barzanjeh, Shabir, et al. “Microwave Quantum Illumination Using a Digital Receiver.” <i>Science Advances</i>, vol. 6, no. 19, eabb0451, AAAS, 2020, doi:<a href=\"https://doi.org/10.1126/sciadv.abb0451\">10.1126/sciadv.abb0451</a>.","chicago":"Barzanjeh, Shabir, S. Pirandola, D Vitali, and Johannes M Fink. “Microwave Quantum Illumination Using a Digital Receiver.” <i>Science Advances</i>. AAAS, 2020. <a href=\"https://doi.org/10.1126/sciadv.abb0451\">https://doi.org/10.1126/sciadv.abb0451</a>.","ama":"Barzanjeh S, Pirandola S, Vitali D, Fink JM. Microwave quantum illumination using a digital receiver. <i>Science Advances</i>. 2020;6(19). doi:<a href=\"https://doi.org/10.1126/sciadv.abb0451\">10.1126/sciadv.abb0451</a>","ieee":"S. Barzanjeh, S. Pirandola, D. Vitali, and J. M. Fink, “Microwave quantum illumination using a digital receiver,” <i>Science Advances</i>, vol. 6, no. 19. AAAS, 2020.","short":"S. Barzanjeh, S. Pirandola, D. Vitali, J.M. Fink, Science Advances 6 (2020).","apa":"Barzanjeh, S., Pirandola, S., Vitali, D., &#38; Fink, J. M. (2020). Microwave quantum illumination using a digital receiver. <i>Science Advances</i>. AAAS. <a href=\"https://doi.org/10.1126/sciadv.abb0451\">https://doi.org/10.1126/sciadv.abb0451</a>","ista":"Barzanjeh S, Pirandola S, Vitali D, Fink JM. 2020. Microwave quantum illumination using a digital receiver. Science Advances. 6(19), eabb0451."},"arxiv":1,"status":"public","type":"journal_article","day":"06","publisher":"AAAS","article_number":"eabb0451","publication_identifier":{"eissn":["2375-2548"]},"month":"05","quality_controlled":"1","_id":"7910","issue":"19","corr_author":"1","article_processing_charge":"No","article_type":"original","author":[{"id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87","last_name":"Barzanjeh","orcid":"0000-0003-0415-1423","full_name":"Barzanjeh, Shabir","first_name":"Shabir"},{"last_name":"Pirandola","full_name":"Pirandola, S.","first_name":"S."},{"first_name":"D","full_name":"Vitali, D","last_name":"Vitali"},{"last_name":"Fink","orcid":"0000-0001-8112-028X","full_name":"Fink, Johannes M","id":"4B591CBA-F248-11E8-B48F-1D18A9856A87","first_name":"Johannes M"}],"language":[{"iso":"eng"}],"oa":1}]