[{"date_updated":"2025-09-30T11:15:10Z","acknowledgement":"We wish to dedicate this work to the memory of our colleague and friend Tom Marsh. Tom's enthusiasm to work on this object and rapid efforts to facilitate data collection truly made this project possible.\r\n\r\nA.C.R. acknowledges support from an NSF Graduate Fellowship. A.C.R. thanks the LSST-DA Data Science Fellowship Program, which is funded by LSST-DA, the Brinson Foundation, and the Moore Foundation; his participation in the program has benefited this work. P.R.-G. acknowledges support by the Spanish Agencia Estatal de Investigación del Ministerio de Ciencia e Innovación (MCIN/AEI) and the European Regional Development Fund (ERDF) under grant PID2021–124879NB–I00. M.R.S. is supported by FONDECYT (grant No. 1221059) and eRO-STEP (SA 2131/15-2 project number 414059771). I.P. acknowledges support from a Royal Society University Research Fellowship (URF/R1/231496). We thank the referee for feedback that improved the clarity of this paper.\r\n\r\nBased on observations made with the Gran Telescopio Canarias (GTC), installed at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofìsica de Canarias, on the island of La Palma. Based on observations obtained with the Samuel Oschin Telescope 48 inch and the 60 inch Telescope at the Palomar Observatory as part of the ZTF project. ZTF is supported by the National Science Foundation under grants No. AST-1440341 and AST-2034437 and a collaboration including current partners Caltech, IPAC, the Weizmann Institute of Science, the Oskar Klein Center at Stockholm University, the University of Maryland, Deutsches Elektronen-Synchrotron and Humboldt University, the TANGO Consortium of Taiwan, the University of Wisconsin at Milwaukee, Trinity College Dublin, Lawrence Livermore National Laboratories, IN2P3, University of Warwick, Ruhr University Bochum, Northwestern University and former partners the University of Washington, Los Alamos National Laboratories, and Lawrence Berkeley National Laboratories. Operations are conducted by COO, IPAC, and UW.\r\n\r\nSome of the data presented herein were obtained at Keck Observatory, which is a private 501(c)3 non-profit organization operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The authors wish to recognize and acknowledge the very significant cultural role and reverence that the summit of Maunakea has always had within the Native Hawaiian community. We are most fortunate to have the opportunity to conduct observations from this mountain. We are also grateful to the staff of Palomar Observatory for their assistance in carrying out observations used in this work.\r\n\r\nPartly based on observations made with the NOT, owned in collaboration by the University of Turku and Aarhus University, and operated jointly by Aarhus University, the University of Turku and the University of Oslo, representing Denmark, Finland and Norway, the University of Iceland and Stockholm University at the Observatorio del Roque de los Muchachos, La Palma, Spain, of the Instituto de Astrofisica de Canarias. The data presented here were obtained with ALFOSC, which is provided by the Instituto de Astrofisica de Andalucia (IAA) under a joint agreement with the University of Copenhagen and NOT. The observation with the SALT was obtained under program 2021-2-LSP-001 (PI: D. Buckley). Polish participation in SALT is funded by grant No. MEiN nr 2021/WK/01. D.A.H.B. acknowledges support from the National Research Foundation.\r\n\r\nThis work presents results from the European Space Agency (ESA) space mission Gaia. Gaia data are being processed by the Gaia Data Processing and Analysis Consortium (DPAC). Funding for the DPAC is provided by national institutions, in particular the institutions participating in the Gaia MultiLateral Agreement (MLA). The Gaia mission website is https://www.cosmos.esa.int/gaia. The Gaia archive website is https://archives.esac.esa.int/gaia. This work made use of data supplied by the UK Swift Science Data Centre at the University of Leicester\r\n\r\nE.C.B. and J.K. acknowledge support from the DIRAC Institute in the Department of Astronomy at the University of Washington. The DIRAC Institute is supported through generous gifts from the Charles and Lisa Simonyi Fund for Arts and Sciences, and the Washington Research Foundation.","article_type":"original","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["520"],"title":"A link between White Dwarf pulsars and polars: Multiwavelength observations of the 9.36-minute period variable Gaia22ayj","external_id":{"arxiv":["2501.01490"],"isi":["001427877700001"]},"status":"public","quality_controlled":"1","OA_place":"publisher","citation":{"ieee":"A. C. Rodriguez <i>et al.</i>, “A link between White Dwarf pulsars and polars: Multiwavelength observations of the 9.36-minute period variable Gaia22ayj,” <i>Publications of the Astronomical Society of the Pacific</i>, vol. 137, no. 2. IOP Publishing, 2025.","mla":"Rodriguez, Antonio C., et al. “A Link between White Dwarf Pulsars and Polars: Multiwavelength Observations of the 9.36-Minute Period Variable Gaia22ayj.” <i>Publications of the Astronomical Society of the Pacific</i>, vol. 137, no. 2, 024202, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/1538-3873/adb0f1\">10.1088/1538-3873/adb0f1</a>.","short":"A.C. Rodriguez, K. El-Badry, P. Hakala, P. Rodríguez-Gil, T. Bao, I. Galiullin, J.A. Kurlander, C.J. Law, I. Pelisoli, M.R. Schreiber, K. Burdge, I. Caiazzo, J.V. Roestel, P. Szkody, A.J. Drake, D.A.H. Buckley, S.B. Potter, B. Gaensicke, K. Mori, E.C. Bellm, S.R. Kulkarni, T.A. Prince, M. Graham, M.M. Kasliwal, S. Rose, Y. Sharma, T. Ahumada, S. Anand, A. Viitanen, A. Wold, T.X. Chen, R. Riddle, R. Smith, Publications of the Astronomical Society of the Pacific 137 (2025).","ista":"Rodriguez AC, El-Badry K, Hakala P, Rodríguez-Gil P, Bao T, Galiullin I, Kurlander JA, Law CJ, Pelisoli I, Schreiber MR, Burdge K, Caiazzo I, Roestel JV, Szkody P, Drake AJ, Buckley DAH, Potter SB, Gaensicke B, Mori K, Bellm EC, Kulkarni SR, Prince TA, Graham M, Kasliwal MM, Rose S, Sharma Y, Ahumada T, Anand S, Viitanen A, Wold A, Chen TX, Riddle R, Smith R. 2025. A link between White Dwarf pulsars and polars: Multiwavelength observations of the 9.36-minute period variable Gaia22ayj. Publications of the Astronomical Society of the Pacific. 137(2), 024202.","ama":"Rodriguez AC, El-Badry K, Hakala P, et al. A link between White Dwarf pulsars and polars: Multiwavelength observations of the 9.36-minute period variable Gaia22ayj. <i>Publications of the Astronomical Society of the Pacific</i>. 2025;137(2). doi:<a href=\"https://doi.org/10.1088/1538-3873/adb0f1\">10.1088/1538-3873/adb0f1</a>","apa":"Rodriguez, A. C., El-Badry, K., Hakala, P., Rodríguez-Gil, P., Bao, T., Galiullin, I., … Smith, R. (2025). A link between White Dwarf pulsars and polars: Multiwavelength observations of the 9.36-minute period variable Gaia22ayj. <i>Publications of the Astronomical Society of the Pacific</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1538-3873/adb0f1\">https://doi.org/10.1088/1538-3873/adb0f1</a>","chicago":"Rodriguez, Antonio C., Kareem El-Badry, Pasi Hakala, Pablo Rodríguez-Gil, Tong Bao, Ilkham Galiullin, Jacob A. Kurlander, et al. “A Link between White Dwarf Pulsars and Polars: Multiwavelength Observations of the 9.36-Minute Period Variable Gaia22ayj.” <i>Publications of the Astronomical Society of the Pacific</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/1538-3873/adb0f1\">https://doi.org/10.1088/1538-3873/adb0f1</a>."},"publication_identifier":{"issn":["0004-6280"]},"month":"02","type":"journal_article","doi":"10.1088/1538-3873/adb0f1","day":"01","abstract":[{"text":"White dwarfs (WDs) are the most abundant compact objects, and recent surveys have suggested that over a third of WDs in accreting binaries host a strong (B  ≳ 1 MG) magnetic field. However, the origin and evolution of WD magnetism remain under debate. Two WD pulsars, AR Sco and J191213.72–441045.1 (J1912), have been found, which are non-accreting binaries hosting rapidly spinning (1.97 minutes and 5.30 minutes, respectively) magnetic WDs. The WD in AR Sco is slowing down on a (math formular) yr timescale. It is believed they will eventually become polars, accreting systems in which a magnetic WD (B  ≈ 10−240 MG) accretes from a Roche lobe-filling donor spinning in sync with the orbit (≳78 minutes). Here, we present multiwavelength data and analysis of Gaia22ayj, which outbursted in 2022 March. We find that Gaia22ayj is a magnetic accreting WD that is rapidly spinning down (math formular\r\n yr) like WD pulsars, but shows clear evidence of accretion, like polars. Strong linear polarization (40%) is detected in Gaia22ayj; such high levels have only been seen in the WD pulsar AR Sco and demonstrate the WD is magnetic. High speed photometry reveals a 9.36 minutes period accompanying a high amplitude (∼2 mag) modulation. We associate this with a WD spin or spin–orbit beat period, not an orbital period as was previously suggested. Fast (60 s) optical spectroscopy reveals a broad \"hump,\" reminiscent of cyclotron emission in polars, between 4000 and 8000 Å. We find an X-ray luminosity of (math formular) in the 0.3–8 keV energy range, while two very large array radio campaigns resulted in a non-detection with a Fr < 15.8 μJy 3σ upper limit. The shared properties of both WD pulsars and polars suggest that Gaia22ayj is a missing link between the two classes of magnetic WD binaries.","lang":"eng"}],"oa_version":"Published Version","arxiv":1,"file":[{"date_updated":"2025-03-25T10:01:24Z","success":1,"file_name":"2025_PubAstronomSocPacific_Rodriguez.pdf","creator":"dernst","checksum":"42d5aa504479c3fdf2a10165a9e3319f","relation":"main_file","access_level":"open_access","file_id":"19455","content_type":"application/pdf","file_size":3291933,"date_created":"2025-03-25T10:01:24Z"}],"date_published":"2025-02-01T00:00:00Z","isi":1,"year":"2025","file_date_updated":"2025-03-25T10:01:24Z","volume":137,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_type":"hybrid","has_accepted_license":"1","oa":1,"publication_status":"published","intvolume":"       137","publication":"Publications of the Astronomical Society of the Pacific","issue":"2","author":[{"full_name":"Rodriguez, Antonio C.","last_name":"Rodriguez","first_name":"Antonio C."},{"first_name":"Kareem","full_name":"El-Badry, Kareem","last_name":"El-Badry"},{"full_name":"Hakala, Pasi","last_name":"Hakala","first_name":"Pasi"},{"full_name":"Rodríguez-Gil, Pablo","last_name":"Rodríguez-Gil","first_name":"Pablo"},{"first_name":"Tong","last_name":"Bao","full_name":"Bao, Tong"},{"full_name":"Galiullin, Ilkham","last_name":"Galiullin","first_name":"Ilkham"},{"full_name":"Kurlander, Jacob A.","last_name":"Kurlander","first_name":"Jacob A."},{"full_name":"Law, Casey J.","last_name":"Law","first_name":"Casey J."},{"first_name":"Ingrid","last_name":"Pelisoli","full_name":"Pelisoli, Ingrid"},{"last_name":"Schreiber","full_name":"Schreiber, Matthias R.","first_name":"Matthias R."},{"first_name":"Kevin","full_name":"Burdge, Kevin","last_name":"Burdge"},{"last_name":"Caiazzo","full_name":"Caiazzo, Ilaria","first_name":"Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d","orcid":"0000-0002-4770-5388"},{"first_name":"Jan Van","last_name":"Roestel","full_name":"Roestel, Jan Van"},{"first_name":"Paula","last_name":"Szkody","full_name":"Szkody, Paula"},{"full_name":"Drake, Andrew J.","last_name":"Drake","first_name":"Andrew J."},{"last_name":"Buckley","full_name":"Buckley, David A.H.","first_name":"David A.H."},{"first_name":"Stephen B.","last_name":"Potter","full_name":"Potter, Stephen B."},{"last_name":"Gaensicke","full_name":"Gaensicke, Boris","first_name":"Boris"},{"full_name":"Mori, Kaya","last_name":"Mori","first_name":"Kaya"},{"first_name":"Eric C.","full_name":"Bellm, Eric C.","last_name":"Bellm"},{"full_name":"Kulkarni, Shrinivas R.","last_name":"Kulkarni","first_name":"Shrinivas R."},{"first_name":"Thomas A.","last_name":"Prince","full_name":"Prince, Thomas A."},{"first_name":"Matthew","last_name":"Graham","full_name":"Graham, Matthew"},{"first_name":"Mansi M.","full_name":"Kasliwal, Mansi M.","last_name":"Kasliwal"},{"first_name":"Sam","full_name":"Rose, Sam","last_name":"Rose"},{"last_name":"Sharma","full_name":"Sharma, Yashvi","first_name":"Yashvi"},{"first_name":"Tomás","last_name":"Ahumada","full_name":"Ahumada, Tomás"},{"first_name":"Shreya","full_name":"Anand, Shreya","last_name":"Anand"},{"last_name":"Viitanen","full_name":"Viitanen, Akke","first_name":"Akke"},{"first_name":"Avery","full_name":"Wold, Avery","last_name":"Wold"},{"first_name":"Tracy X.","last_name":"Chen","full_name":"Chen, Tracy X."},{"full_name":"Riddle, Reed","last_name":"Riddle","first_name":"Reed"},{"full_name":"Smith, Roger","last_name":"Smith","first_name":"Roger"}],"article_number":"024202","department":[{"_id":"IlCa"}],"_id":"19439","language":[{"iso":"eng"}],"publisher":"IOP Publishing","date_created":"2025-03-23T23:01:26Z","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)"},{"article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","date_created":"2025-03-23T23:01:26Z","publisher":"Wiley","_id":"19440","language":[{"iso":"eng"}],"department":[{"_id":"MaKw"}],"project":[{"name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020","grant_number":"101034413"}],"article_number":"e21286","author":[{"full_name":"Alon, Yahav","last_name":"Alon","first_name":"Yahav"},{"full_name":"Anastos, Michael","last_name":"Anastos","first_name":"Michael","id":"0b2a4358-bb35-11ec-b7b9-e3279b593dbb"}],"issue":"2","publication":"Random Structures and Algorithms","intvolume":"        66","publication_status":"published","ec_funded":1,"oa":1,"has_accepted_license":"1","OA_type":"hybrid","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":66,"file_date_updated":"2025-03-25T11:46:27Z","year":"2025","isi":1,"date_published":"2025-03-01T00:00:00Z","file":[{"access_level":"open_access","relation":"main_file","checksum":"6067747e805fa356d560dc45f2a89918","creator":"dernst","file_name":"2025_RandomStruc_Alon.pdf","success":1,"date_updated":"2025-03-25T11:46:27Z","date_created":"2025-03-25T11:46:27Z","file_size":549236,"content_type":"application/pdf","file_id":"19459"}],"oa_version":"Published Version","abstract":[{"text":"Let μ(G) denote the minimum number of edges whose addition to G results in a Hamiltonian graph, and let μ^(G) denote the minimum number of edges whose addition to G results in a pancyclic graph. We study the distributions of μ(G),μ^(G) in the context of binomial random graphs. Letting d=d(n):=n⋅p, we prove that there exists a function f:R+→[0,1] of order f(d)=12de−d+e−d+O(d6e−3d) such that, if G∼G(n,p) with 20≤d(n)≤0.4logn, then with high probability μ(G)=(1+o(1))⋅f(d)⋅n. Let ni(G) denote the number of degree i vertices in G. A trivial lower bound on μ(G) is given by the expression n0(G)+⌈12n1(G)⌉. In the denser regime of random graphs, we show that if np−13logn−2loglogn→∞ and G∼G(n,p) then, with high probability, μ(G)=n0(G)+⌈12n1(G)⌉. For completion to pancyclicity, we show that if G∼G(n,p) and np≥20 then, with high probability, μ^(G)=μ(G). Finally, we present a polynomial time algorithm such that, if G∼G(n,p) and np≥20, then, with high probability, the algorithm returns a set of edges of size μ(G) whose addition to G results in a pancyclic (and therefore also Hamiltonian) graph.","lang":"eng"}],"arxiv":1,"day":"01","doi":"10.1002/rsa.21286","type":"journal_article","month":"03","publication_identifier":{"eissn":["1098-2418"],"issn":["1042-9832"]},"citation":{"chicago":"Alon, Yahav, and Michael Anastos. “The Completion Numbers of Hamiltonicity and Pancyclicity in Random Graphs.” <i>Random Structures and Algorithms</i>. Wiley, 2025. <a href=\"https://doi.org/10.1002/rsa.21286\">https://doi.org/10.1002/rsa.21286</a>.","apa":"Alon, Y., &#38; Anastos, M. (2025). The completion numbers of hamiltonicity and pancyclicity in random graphs. <i>Random Structures and Algorithms</i>. Wiley. <a href=\"https://doi.org/10.1002/rsa.21286\">https://doi.org/10.1002/rsa.21286</a>","ista":"Alon Y, Anastos M. 2025. The completion numbers of hamiltonicity and pancyclicity in random graphs. Random Structures and Algorithms. 66(2), e21286.","ama":"Alon Y, Anastos M. The completion numbers of hamiltonicity and pancyclicity in random graphs. <i>Random Structures and Algorithms</i>. 2025;66(2). doi:<a href=\"https://doi.org/10.1002/rsa.21286\">10.1002/rsa.21286</a>","short":"Y. Alon, M. Anastos, Random Structures and Algorithms 66 (2025).","mla":"Alon, Yahav, and Michael Anastos. “The Completion Numbers of Hamiltonicity and Pancyclicity in Random Graphs.” <i>Random Structures and Algorithms</i>, vol. 66, no. 2, e21286, Wiley, 2025, doi:<a href=\"https://doi.org/10.1002/rsa.21286\">10.1002/rsa.21286</a>.","ieee":"Y. Alon and M. Anastos, “The completion numbers of hamiltonicity and pancyclicity in random graphs,” <i>Random Structures and Algorithms</i>, vol. 66, no. 2. Wiley, 2025."},"OA_place":"publisher","quality_controlled":"1","status":"public","external_id":{"arxiv":["2304.03710"],"isi":["001420226800001"]},"title":"The completion numbers of hamiltonicity and pancyclicity in random graphs","ddc":["510"],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png"},"article_type":"original","acknowledgement":"The authors would like to express their thanks to the referees of the article for their valuable input towards improving the presentation of our result. This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101034413.","date_updated":"2025-09-30T11:15:41Z"},{"publication_identifier":{"eissn":["1936-086X"],"issn":["1936-0851"]},"citation":{"mla":"Carrasco, Celso, et al. “Characterization of Nonequilibrium Interactions of Catalytic Microswimmers Using Phoretically Responsive Nanotracers.” <i>ACS Nano</i>, vol. 19, no. 11, American Chemical Society, 2025, pp. 11133–45, doi:<a href=\"https://doi.org/10.1021/acsnano.4c18078\">10.1021/acsnano.4c18078</a>.","ieee":"C. Carrasco, Q. Martinet, Z. Shen, J. Lintuvuori, J. A. Palacci, and A. Aubret, “Characterization of nonequilibrium interactions of catalytic microswimmers using phoretically responsive nanotracers,” <i>ACS Nano</i>, vol. 19, no. 11. American Chemical Society, pp. 11133–11145, 2025.","chicago":"Carrasco, Celso, Quentin Martinet, Zaiyi Shen, Juho Lintuvuori, Jérémie A Palacci, and Antoine Aubret. “Characterization of Nonequilibrium Interactions of Catalytic Microswimmers Using Phoretically Responsive Nanotracers.” <i>ACS Nano</i>. American Chemical Society, 2025. <a href=\"https://doi.org/10.1021/acsnano.4c18078\">https://doi.org/10.1021/acsnano.4c18078</a>.","apa":"Carrasco, C., Martinet, Q., Shen, Z., Lintuvuori, J., Palacci, J. A., &#38; Aubret, A. (2025). Characterization of nonequilibrium interactions of catalytic microswimmers using phoretically responsive nanotracers. <i>ACS Nano</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsnano.4c18078\">https://doi.org/10.1021/acsnano.4c18078</a>","ama":"Carrasco C, Martinet Q, Shen Z, Lintuvuori J, Palacci JA, Aubret A. Characterization of nonequilibrium interactions of catalytic microswimmers using phoretically responsive nanotracers. <i>ACS Nano</i>. 2025;19(11):11133-11145. doi:<a href=\"https://doi.org/10.1021/acsnano.4c18078\">10.1021/acsnano.4c18078</a>","ista":"Carrasco C, Martinet Q, Shen Z, Lintuvuori J, Palacci JA, Aubret A. 2025. Characterization of nonequilibrium interactions of catalytic microswimmers using phoretically responsive nanotracers. ACS Nano. 19(11), 11133–11145.","short":"C. Carrasco, Q. Martinet, Z. Shen, J. Lintuvuori, J.A. Palacci, A. Aubret, ACS Nano 19 (2025) 11133–11145."},"month":"03","type":"journal_article","doi":"10.1021/acsnano.4c18078","day":"11","oa_version":"Submitted Version","abstract":[{"text":"Catalytic microswimmers convert the chemical energy from fuel into motion. They sustain chemical gradients and fluid flows that propel them by phoresis. This leads to unconventional behavior and collective dynamics, such as self-organization into complex structures. Characterizing the nonequilibrium interactions of microswimmers is crucial for advancing our understanding of active systems. However, this remains a challenge owing to the importance of fluctuations at the microscale and the difficulty in disentangling the different contributions to the interactions. Here, we show a massive dependence of the nonequilibrium interactions on the shape of catalytic microswimmers. We perform tracking experiments at high throughput to map interactions between nanocolloidal tracers and dimeric microswimmers of various aspect ratios. Our method leverages dual tracers with differing phoretic mobilities to quantitatively disentangle phoretic motion from hydrodynamic advection. This approach is validated through experiments on single chemically active sites and on immobilized catalytic microswimmers. We further investigate the activity-driven interactions of free microswimmers and directly measure their phoretic interactions. When compared to standard models, our findings highlight the important role of osmotic flows for microswimmers near surfaces and reveal an enhanced contribution of hydrodynamic advection relative to phoretic motion as the size of the microswimmer increases. Our study provides robust measurements of the nonequilibrium interactions from catalytic microswimmers and lays the groundwork for a realistic description of active systems.","lang":"eng"}],"date_published":"2025-03-11T00:00:00Z","pmid":1,"isi":1,"main_file_link":[{"open_access":"1","url":"https://hal.science/hal-04682818v2"}],"date_updated":"2025-10-16T10:26:59Z","acknowledgement":"The authors thank M. Perrin and A. Allard for enlightening discussions. This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/P35206]. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement No. 886024.","article_type":"original","title":"Characterization of nonequilibrium interactions of catalytic microswimmers using phoretically responsive nanotracers","external_id":{"pmid":["40069094"],"isi":["001443359300001"]},"page":"11133-11145","status":"public","quality_controlled":"1","OA_place":"repository","author":[{"last_name":"Carrasco","full_name":"Carrasco, Celso","first_name":"Celso"},{"last_name":"Martinet","full_name":"Martinet, Quentin","id":"b37485a8-d343-11eb-a0e9-df8c484ef8ab","orcid":"0000-0002-2916-6632","first_name":"Quentin"},{"first_name":"Zaiyi","full_name":"Shen, Zaiyi","last_name":"Shen"},{"last_name":"Lintuvuori","full_name":"Lintuvuori, Juho","first_name":"Juho"},{"id":"8fb92548-2b22-11eb-b7c1-a3f0d08d7c7d","first_name":"Jérémie A","orcid":"0000-0002-7253-9465","full_name":"Palacci, Jérémie A","last_name":"Palacci"},{"full_name":"Aubret, Antoine","last_name":"Aubret","first_name":"Antoine"}],"project":[{"grant_number":"P35206","_id":"eb99c9bb-77a9-11ec-83b8-9f8cffa20a35","name":"Emergent Behavior in Spinning Active Matter"}],"department":[{"_id":"JePa"}],"language":[{"iso":"eng"}],"_id":"19441","publisher":"American Chemical Society","date_created":"2025-03-23T23:01:26Z","scopus_import":"1","article_processing_charge":"No","year":"2025","volume":19,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"green","oa":1,"publication_status":"published","intvolume":"        19","publication":"ACS Nano","issue":"11"},{"acknowledgement":"We would like to express our sincere gratitude to all the data providers who carried out fieldwork in different regions of the Arctic and published their data, which we used for our meta-analysis. We recognise the hard work and dedication of these individuals, without whom this paper would not have been possible. We are grateful to the editor and the anonymous reviewer for their time and valuable feedback on this manuscript. We particularly appreciate the detailed and constructive comments provided by reviewer Mara Baudena, which significantly strengthened our work. We also acknowledge the Indigenous peoples and rural communities of the Arctic, whose traditional knowledge, rights, and interests are integral to the stewardship and study of these ecosystems. This work was funded in part by the U.S. National Aeronautics and Space Administration (NASA) grant 80NSSC22K1256 (GVF). Open Access funding enabled and organized by Projekt DEAL.","date_updated":"2025-12-30T08:09:47Z","ddc":["550","570"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"review","page":"1042-1056","external_id":{"isi":["001443422900001"]},"title":"Arctic tundra ecosystems under fire—Alternative ecosystem states in a changing climate?","OA_place":"publisher","quality_controlled":"1","status":"public","month":"05","publication_identifier":{"eissn":["1365-2745"],"issn":["0022-0477"]},"citation":{"short":"R.J. Heim, A.V. Rocha, V. Zemlianskii, K. Barrett, H. Bültmann, A. Breen, G.V. Frost, T.N. Hollingsworth, R. Jandt, M. Kozlova, A. Kurka, M.T. Jorgenson, S.M. Landhäusser, M.M. Loranty, E.A. Miller, K. Narita, E. Pravdolyubova, N. Hölzel, G. Schaepman-Strub, Journal of Ecology 113 (2025) 1042–1056.","ista":"Heim RJ, Rocha AV, Zemlianskii V, Barrett K, Bültmann H, Breen A, Frost GV, Hollingsworth TN, Jandt R, Kozlova M, Kurka A, Jorgenson MT, Landhäusser SM, Loranty MM, Miller EA, Narita K, Pravdolyubova E, Hölzel N, Schaepman-Strub G. 2025. Arctic tundra ecosystems under fire—Alternative ecosystem states in a changing climate? Journal of Ecology. 113(5), 1042–1056.","ama":"Heim RJ, Rocha AV, Zemlianskii V, et al. Arctic tundra ecosystems under fire—Alternative ecosystem states in a changing climate? <i>Journal of Ecology</i>. 2025;113(5):1042-1056. doi:<a href=\"https://doi.org/10.1111/1365-2745.70022\">10.1111/1365-2745.70022</a>","apa":"Heim, R. J., Rocha, A. V., Zemlianskii, V., Barrett, K., Bültmann, H., Breen, A., … Schaepman-Strub, G. (2025). Arctic tundra ecosystems under fire—Alternative ecosystem states in a changing climate? <i>Journal of Ecology</i>. Wiley. <a href=\"https://doi.org/10.1111/1365-2745.70022\">https://doi.org/10.1111/1365-2745.70022</a>","chicago":"Heim, Ramona Julia, Adrian V. Rocha, Vitalii Zemlianskii, Kirsten Barrett, Helga Bültmann, Amy Breen, Gerald Verner Frost, et al. “Arctic Tundra Ecosystems under Fire—Alternative Ecosystem States in a Changing Climate?” <i>Journal of Ecology</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/1365-2745.70022\">https://doi.org/10.1111/1365-2745.70022</a>.","ieee":"R. J. Heim <i>et al.</i>, “Arctic tundra ecosystems under fire—Alternative ecosystem states in a changing climate?,” <i>Journal of Ecology</i>, vol. 113, no. 5. Wiley, pp. 1042–1056, 2025.","mla":"Heim, Ramona Julia, et al. “Arctic Tundra Ecosystems under Fire—Alternative Ecosystem States in a Changing Climate?” <i>Journal of Ecology</i>, vol. 113, no. 5, Wiley, 2025, pp. 1042–56, doi:<a href=\"https://doi.org/10.1111/1365-2745.70022\">10.1111/1365-2745.70022</a>."},"doi":"10.1111/1365-2745.70022","type":"journal_article","oa_version":"Published Version","abstract":[{"lang":"eng","text":"1. Climate change is expected to induce shifts in the composition, structure and functioning of Arctic tundra ecosystems. Increases in the frequency and severity of tundra fires have the potential to catalyse vegetation transitions with far-reaching local, regional and global consequences.\r\n2. We propose that post-fire tundra recovery, coupled with climate change, may not necessarily lead to pre-fire conditions. Our hypothesis, based on surveys and literature, suggests two climate–fire driven trajectories. One trajectory results in increased woody vegetation under low fire frequency; the other results in grass dominance under high frequency.\r\n3. Future research should address uncertainties regarding possible tundra ecosystem shifts linked to fires, using methods that encompass greater temporal and spatial scales than previously addressed. More case studies, especially in underrepresented regions and ecosystem types, are essential to broaden the empirical basis for forecasts and potential fire management strategies.\r\n4. Synthesis. Our review synthesises current knowledge on post-fire vegetation trajectories in Arctic tundra ecosystems, highlighting potential transitions and alternative ecosystem states and their implications. We discuss challenges in defining and predicting these trajectories as well as future directions."}],"day":"01","isi":1,"date_published":"2025-05-01T00:00:00Z","file":[{"date_updated":"2025-12-30T08:08:18Z","success":1,"file_name":"2025_JournEcology_Heim.pdf","creator":"dernst","checksum":"e2785ae265e211b4dc7fc9c5b7744948","relation":"main_file","access_level":"open_access","file_id":"20890","content_type":"application/pdf","date_created":"2025-12-30T08:08:18Z","file_size":2662766}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":113,"file_date_updated":"2025-12-30T08:08:18Z","year":"2025","PlanS_conform":"1","publication_status":"published","oa":1,"OA_type":"hybrid","has_accepted_license":"1","intvolume":"       113","issue":"5","publication":"Journal of Ecology","author":[{"first_name":"Ramona Julia","last_name":"Heim","full_name":"Heim, Ramona Julia"},{"full_name":"Rocha, Adrian V.","last_name":"Rocha","first_name":"Adrian V."},{"full_name":"Zemlianskii, Vitalii","last_name":"Zemlianskii","first_name":"Vitalii"},{"first_name":"Kirsten","full_name":"Barrett, Kirsten","last_name":"Barrett"},{"first_name":"Helga","full_name":"Bültmann, Helga","last_name":"Bültmann"},{"full_name":"Breen, Amy","last_name":"Breen","first_name":"Amy"},{"last_name":"Frost","full_name":"Frost, Gerald Verner","first_name":"Gerald Verner"},{"full_name":"Hollingsworth, Teresa Nettleton","last_name":"Hollingsworth","first_name":"Teresa Nettleton"},{"last_name":"Jandt","full_name":"Jandt, Randi","first_name":"Randi"},{"first_name":"Maria","full_name":"Kozlova, Maria","last_name":"Kozlova"},{"full_name":"Kurka, Anastasiya","last_name":"Kurka","first_name":"Anastasiya"},{"last_name":"Jorgenson","full_name":"Jorgenson, Mark Torre","first_name":"Mark Torre"},{"first_name":"Simon M.","last_name":"Landhäusser","full_name":"Landhäusser, Simon M."},{"first_name":"Michael Mark","full_name":"Loranty, Michael Mark","last_name":"Loranty"},{"first_name":"Eric A.","full_name":"Miller, Eric A.","last_name":"Miller"},{"full_name":"Narita, Kenji","last_name":"Narita","first_name":"Kenji"},{"first_name":"Evgeniya","id":"0b30719b-13f0-11ed-ab2a-94498bc6a278","full_name":"Pravdolyubova, Evgeniya","last_name":"Pravdolyubova"},{"full_name":"Hölzel, Norbert","last_name":"Hölzel","first_name":"Norbert"},{"first_name":"Gabriela","last_name":"Schaepman-Strub","full_name":"Schaepman-Strub, Gabriela"}],"department":[{"_id":"NiBa"}],"publisher":"Wiley","language":[{"iso":"eng"}],"_id":"19442","article_processing_charge":"Yes (via OA deal)","scopus_import":"1","date_created":"2025-03-23T23:01:27Z"},{"page":"820-827.e4","external_id":{"pmid":["39947174"],"isi":["001463196100001"]},"title":"FakET: Simulating cryo-electron tomograms with neural style transfer","OA_place":"publisher","quality_controlled":"1","status":"public","acknowledgement":"The IMP and D.H. are generously funded by Boehringer Ingelheim. We thank Julius Berner from the Mathematical Data Science group @ UniVie, Ilja Gubins and Marten Chaillet from the SHREC team, and the members of the Haselbach lab for helpful discussions.","date_updated":"2025-09-30T11:13:02Z","ddc":["570"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"original","oa_version":"Published Version","abstract":[{"text":"In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training datasets. The protracted generation time of physics-based models, often employed to produce these datasets, limits their broad applicability. We introduce FakET, a method based on neural style transfer, capable of simulating the forward operator of any cryo transmission electron microscope. It can be used to adapt a synthetic training dataset according to reference data producing high-quality simulated micrographs or tilt-series. To assess the quality of our generated data, we used it to train a state-of-the-art localization and classification architecture and compared its performance with a counterpart trained on benchmark data. Remarkably, our technique matches the performance, boosts data generation speed 750x, uses 33x less memory, and scales well to typical transmission electron microscope detector sizes. It leverages GPU acceleration and parallel processing. The source code is available at https://github.com/paloha/faket/.","lang":"eng"}],"day":"03","isi":1,"pmid":1,"date_published":"2025-04-03T00:00:00Z","file":[{"content_type":"application/pdf","file_id":"20130","file_size":4367530,"date_created":"2025-08-05T12:15:13Z","file_name":"2025_Structure_Harar.pdf","success":1,"date_updated":"2025-08-05T12:15:13Z","relation":"main_file","access_level":"open_access","creator":"dernst","checksum":"f346bc357a66a88cca3d0eb95793fb73"}],"month":"04","publication_identifier":{"eissn":["1878-4186"],"issn":["0969-2126"]},"citation":{"chicago":"Harar, Pavol, Lukas Herrmann, Philipp Grohs, and David Haselbach. “FakET: Simulating Cryo-Electron Tomograms with Neural Style Transfer.” <i>Structure</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.str.2025.01.020\">https://doi.org/10.1016/j.str.2025.01.020</a>.","apa":"Harar, P., Herrmann, L., Grohs, P., &#38; Haselbach, D. (2025). FakET: Simulating cryo-electron tomograms with neural style transfer. <i>Structure</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.str.2025.01.020\">https://doi.org/10.1016/j.str.2025.01.020</a>","ista":"Harar P, Herrmann L, Grohs P, Haselbach D. 2025. FakET: Simulating cryo-electron tomograms with neural style transfer. Structure. 33(4), 820–827.e4.","ama":"Harar P, Herrmann L, Grohs P, Haselbach D. FakET: Simulating cryo-electron tomograms with neural style transfer. <i>Structure</i>. 2025;33(4):820-827.e4. doi:<a href=\"https://doi.org/10.1016/j.str.2025.01.020\">10.1016/j.str.2025.01.020</a>","short":"P. Harar, L. Herrmann, P. Grohs, D. Haselbach, Structure 33 (2025) 820–827.e4.","mla":"Harar, Pavol, et al. “FakET: Simulating Cryo-Electron Tomograms with Neural Style Transfer.” <i>Structure</i>, vol. 33, no. 4, Elsevier, 2025, p. 820–827.e4, doi:<a href=\"https://doi.org/10.1016/j.str.2025.01.020\">10.1016/j.str.2025.01.020</a>.","ieee":"P. Harar, L. Herrmann, P. Grohs, and D. Haselbach, “FakET: Simulating cryo-electron tomograms with neural style transfer,” <i>Structure</i>, vol. 33, no. 4. Elsevier, p. 820–827.e4, 2025."},"doi":"10.1016/j.str.2025.01.020","type":"journal_article","intvolume":"        33","corr_author":"1","issue":"4","publication":"Structure","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":33,"file_date_updated":"2025-08-05T12:15:13Z","year":"2025","publication_status":"published","PlanS_conform":"1","oa":1,"has_accepted_license":"1","OA_type":"hybrid","publisher":"Elsevier","language":[{"iso":"eng"}],"_id":"19443","article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","related_material":{"link":[{"url":"https://github.com/paloha/faket/","relation":"software"}]},"date_created":"2025-03-23T23:01:27Z","author":[{"first_name":"Pavol","id":"e03d953a-6e8c-11ef-99e4-f0717d385cd5","orcid":"0000-0001-5206-1794","full_name":"Harar, Pavol","last_name":"Harar"},{"full_name":"Herrmann, Lukas","last_name":"Herrmann","first_name":"Lukas"},{"full_name":"Grohs, Philipp","last_name":"Grohs","first_name":"Philipp"},{"first_name":"David","full_name":"Haselbach, David","last_name":"Haselbach"}],"department":[{"_id":"AlMi"}]},{"department":[{"_id":"GaNo"}],"author":[{"first_name":"Sergiu P.","full_name":"Pașca, Sergiu P.","last_name":"Pașca"},{"first_name":"Paola","last_name":"Arlotta","full_name":"Arlotta, Paola"},{"first_name":"Helen S.","last_name":"Bateup","full_name":"Bateup, Helen S."},{"full_name":"Camp, J. Gray","last_name":"Camp","first_name":"J. Gray"},{"first_name":"Silvia","last_name":"Cappello","full_name":"Cappello, Silvia"},{"last_name":"Gage","full_name":"Gage, Fred H.","first_name":"Fred H."},{"full_name":"Knoblich, Jürgen A.","last_name":"Knoblich","first_name":"Jürgen A."},{"full_name":"Kriegstein, Arnold R.","last_name":"Kriegstein","first_name":"Arnold R."},{"last_name":"Lancaster","full_name":"Lancaster, Madeline A.","first_name":"Madeline A."},{"full_name":"Ming, Guo Li","last_name":"Ming","first_name":"Guo Li"},{"full_name":"Novarino, Gaia","last_name":"Novarino","orcid":"0000-0002-7673-7178","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","first_name":"Gaia"},{"first_name":"Hideyuki","full_name":"Okano, Hideyuki","last_name":"Okano"},{"first_name":"Malin","full_name":"Parmar, Malin","last_name":"Parmar"},{"first_name":"In Hyun","full_name":"Park, In Hyun","last_name":"Park"},{"first_name":"Orly","last_name":"Reiner","full_name":"Reiner, Orly"},{"last_name":"Song","full_name":"Song, Hongjun","first_name":"Hongjun"},{"first_name":"Lorenz","full_name":"Studer, Lorenz","last_name":"Studer"},{"full_name":"Takahashi, Jun","last_name":"Takahashi","first_name":"Jun"},{"first_name":"Sally","full_name":"Temple, Sally","last_name":"Temple"},{"full_name":"Testa, Giuseppe","last_name":"Testa","first_name":"Giuseppe"},{"first_name":"Barbara","last_name":"Treutlein","full_name":"Treutlein, Barbara"},{"full_name":"Vaccarino, Flora M.","last_name":"Vaccarino","first_name":"Flora M."},{"first_name":"Pierre","last_name":"Vanderhaeghen","full_name":"Vanderhaeghen, Pierre"},{"last_name":"Young-Pearse","full_name":"Young-Pearse, Tracy","first_name":"Tracy"}],"article_processing_charge":"No","scopus_import":"1","date_created":"2025-03-23T23:01:27Z","publisher":"Springer Nature","language":[{"iso":"eng"}],"_id":"19444","publication_status":"published","OA_type":"closed access","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":639,"year":"2025","issue":"8054","publication":"Nature","intvolume":"       639","type":"journal_article","doi":"10.1038/s41586-024-08487-6","month":"03","citation":{"ieee":"S. P. Pașca <i>et al.</i>, “A framework for neural organoids, assembloids and transplantation studies,” <i>Nature</i>, vol. 639, no. 8054. Springer Nature, pp. 315–320, 2025.","mla":"Pașca, Sergiu P., et al. “A Framework for Neural Organoids, Assembloids and Transplantation Studies.” <i>Nature</i>, vol. 639, no. 8054, Springer Nature, 2025, pp. 315–20, doi:<a href=\"https://doi.org/10.1038/s41586-024-08487-6\">10.1038/s41586-024-08487-6</a>.","ista":"Pașca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Novarino G, Okano H, Parmar M, Park IH, Reiner O, Song H, Studer L, Takahashi J, Temple S, Testa G, Treutlein B, Vaccarino FM, Vanderhaeghen P, Young-Pearse T. 2025. A framework for neural organoids, assembloids and transplantation studies. Nature. 639(8054), 315–320.","ama":"Pașca SP, Arlotta P, Bateup HS, et al. A framework for neural organoids, assembloids and transplantation studies. <i>Nature</i>. 2025;639(8054):315-320. doi:<a href=\"https://doi.org/10.1038/s41586-024-08487-6\">10.1038/s41586-024-08487-6</a>","short":"S.P. Pașca, P. Arlotta, H.S. Bateup, J.G. Camp, S. Cappello, F.H. Gage, J.A. Knoblich, A.R. Kriegstein, M.A. Lancaster, G.L. Ming, G. Novarino, H. Okano, M. Parmar, I.H. Park, O. Reiner, H. Song, L. Studer, J. Takahashi, S. Temple, G. Testa, B. Treutlein, F.M. Vaccarino, P. Vanderhaeghen, T. Young-Pearse, Nature 639 (2025) 315–320.","apa":"Pașca, S. P., Arlotta, P., Bateup, H. S., Camp, J. G., Cappello, S., Gage, F. H., … Young-Pearse, T. (2025). A framework for neural organoids, assembloids and transplantation studies. <i>Nature</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41586-024-08487-6\">https://doi.org/10.1038/s41586-024-08487-6</a>","chicago":"Pașca, Sergiu P., Paola Arlotta, Helen S. Bateup, J. Gray Camp, Silvia Cappello, Fred H. Gage, Jürgen A. Knoblich, et al. “A Framework for Neural Organoids, Assembloids and Transplantation Studies.” <i>Nature</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41586-024-08487-6\">https://doi.org/10.1038/s41586-024-08487-6</a>."},"publication_identifier":{"issn":["0028-0836"],"eissn":["1476-4687"]},"isi":1,"pmid":1,"date_published":"2025-03-13T00:00:00Z","abstract":[{"lang":"eng","text":"As the field of neural organoids and assembloids expands, there is an emergent need for guidance and advice on designing, conducting and reporting experiments to increase the reproducibility and utility of these models. In this Perspective, we present a framework for the experimental process that encompasses ensuring the quality and integrity of human pluripotent stem cells, characterizing and manipulating neural cells in vitro, transplantation techniques and considerations for modelling human development, evolution and disease. As with all scientific endeavours, we advocate for rigorous experimental designs tailored to explicit scientific questions as well as transparent methodologies and data sharing to provide useful knowledge for current research practices and for developing regulatory standards."}],"oa_version":"None","day":"13","article_type":"original","acknowledgement":"The authors thank members of their laboratories who provided feedback on earlier versions of this manuscript, including A. Jourdon, V. Mariano, T. L. Li, N. Caporale, E. Villa and M. Sutcliffe.","date_updated":"2025-09-30T11:13:47Z","quality_controlled":"1","status":"public","page":"315-320","external_id":{"isi":["001437461900001"],"pmid":["39653126"]},"title":"A framework for neural organoids, assembloids and transplantation studies"},{"publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9789819628445"]},"citation":{"ieee":"J. M. Křišťan and J. Svoboda, “Reconfiguration using generalized token jumping,” in <i>19th International Conference and Workshops on Algorithms and Computation</i>, Chengdu, China, 2025, vol. 15411, pp. 244–265.","mla":"Křišťan, Jan Matyáš, and Jakub Svoboda. “Reconfiguration Using Generalized Token Jumping.” <i>19th International Conference and Workshops on Algorithms and Computation</i>, vol. 15411, Springer Nature, 2025, pp. 244–65, doi:<a href=\"https://doi.org/10.1007/978-981-96-2845-2_16\">10.1007/978-981-96-2845-2_16</a>.","short":"J.M. Křišťan, J. Svoboda, in:, 19th International Conference and Workshops on Algorithms and Computation, Springer Nature, 2025, pp. 244–265.","ama":"Křišťan JM, Svoboda J. Reconfiguration using generalized token jumping. In: <i>19th International Conference and Workshops on Algorithms and Computation</i>. Vol 15411. Springer Nature; 2025:244-265. doi:<a href=\"https://doi.org/10.1007/978-981-96-2845-2_16\">10.1007/978-981-96-2845-2_16</a>","ista":"Křišťan JM, Svoboda J. 2025. Reconfiguration using generalized token jumping. 19th International Conference and Workshops on Algorithms and Computation. WALCOM: International Conference and Workshops on Algorithms and Computation, LNCS, vol. 15411, 244–265.","apa":"Křišťan, J. M., &#38; Svoboda, J. (2025). Reconfiguration using generalized token jumping. In <i>19th International Conference and Workshops on Algorithms and Computation</i> (Vol. 15411, pp. 244–265). Chengdu, China: Springer Nature. <a href=\"https://doi.org/10.1007/978-981-96-2845-2_16\">https://doi.org/10.1007/978-981-96-2845-2_16</a>","chicago":"Křišťan, Jan Matyáš, and Jakub Svoboda. “Reconfiguration Using Generalized Token Jumping.” In <i>19th International Conference and Workshops on Algorithms and Computation</i>, 15411:244–65. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/978-981-96-2845-2_16\">https://doi.org/10.1007/978-981-96-2845-2_16</a>."},"month":"02","doi":"10.1007/978-981-96-2845-2_16","type":"conference","day":"20","arxiv":1,"oa_version":"Preprint","abstract":[{"text":"In reconfiguration, we are given two solutions to a graph problem, such as Vertex Cover or Dominating Set, with each solution represented by a placement of tokens on vertices of the graph. Our task is to reconfigure one into the other using small steps while ensuring the intermediate configurations of tokens are also valid solutions. The two commonly studied settings are Token Jumping and Token Sliding, which allows moving a single token to an arbitrary or an adjacent vertex, respectively.\r\n\r\nWe introduce new rules that generalize Token Jumping, parameterized by the number of tokens allowed to move at once and by the maximum distance of each move. Our main contribution is identifying minimal rules that allow reconfiguring any possible given solution into any other for Independent Set, Vertex Cover, and Dominating Set. For each minimal rule, we also provide an efficient algorithm that finds a corresponding reconfiguration sequence.\r\n\r\nWe further focus on the rule that allows each token to move to an adjacent vertex in a single step. This natural variant turns out to be the minimal rule that guarantees reconfigurability for Vertex Cover. We determine the computational complexity of deciding whether a (shortest) reconfiguration sequence exists under this rule for the three studied problems. While reachability for Vertex Cover is shown to be in P, finding a shortest sequence is shown to be NP-complete. For Independent Set and Dominating Set, even reachability is shown to be PSPACE-complete.","lang":"eng"}],"date_published":"2025-02-20T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2411.12582"}],"isi":1,"date_updated":"2025-09-30T11:14:33Z","acknowledgement":"J. M. Křišťan acknowledges the support of the Czech Science Foundation Grant No. 24-12046S. This work was supported by the Grant Agency of the Czech Technical University in Prague, grant No. SGS23/205/OHK3/3T/18. J. Svoboda acknowledges the support of the ERC CoG 863818 (ForM-SMArt) grant.","alternative_title":["LNCS"],"title":"Reconfiguration using generalized token jumping","external_id":{"arxiv":["2411.12582"],"isi":["001537885900016"]},"page":"244-265","status":"public","quality_controlled":"1","OA_place":"repository","author":[{"first_name":"Jan Matyáš","full_name":"Křišťan, Jan Matyáš","last_name":"Křišťan"},{"full_name":"Svoboda, Jakub","last_name":"Svoboda","first_name":"Jakub","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","orcid":"0000-0002-1419-3267"}],"project":[{"name":"Formal Methods for Stochastic Models: Algorithms and Applications","call_identifier":"H2020","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","grant_number":"863818"}],"department":[{"_id":"KrCh"}],"_id":"19445","language":[{"iso":"eng"}],"publisher":"Springer Nature","date_created":"2025-03-23T23:01:27Z","scopus_import":"1","article_processing_charge":"No","year":"2025","volume":15411,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_type":"green","oa":1,"ec_funded":1,"publication_status":"published","intvolume":"     15411","conference":{"location":"Chengdu, China","end_date":"2025-03-02","start_date":"2025-02-28","name":"WALCOM: International Conference and Workshops on Algorithms and Computation"},"publication":"19th International Conference and Workshops on Algorithms and Computation"},{"related_material":{"link":[{"url":"https://github.com/hchiossi/hpc-hierarchy","relation":"software"}],"record":[{"status":"public","relation":"research_data","id":"18991"}]},"date_created":"2025-03-25T07:38:35Z","article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","_id":"19453","language":[{"iso":"eng"}],"publisher":"National Academy of Sciences","article_number":"e2417025122","department":[{"_id":"GaTk"},{"_id":"JoCs"}],"project":[{"name":"International IST Doctoral Program","grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020"}],"author":[{"id":"2BBA502C-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0004-2973-278X","first_name":"Heloisa","full_name":"Chiossi, Heloisa","last_name":"Chiossi"},{"full_name":"Nardin, Michele","last_name":"Nardin","first_name":"Michele","id":"30BD0376-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8849-6570"},{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455","first_name":"Gašper","last_name":"Tkačik","full_name":"Tkačik, Gašper"},{"full_name":"Csicsvari, Jozsef L","last_name":"Csicsvari","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5193-4036","first_name":"Jozsef L"}],"publication":"Proceedings of the National Academy of Sciences","issue":"11","corr_author":"1","intvolume":"       122","oa":1,"has_accepted_license":"1","OA_type":"hybrid","publication_status":"published","ec_funded":1,"file_date_updated":"2025-03-25T07:49:04Z","year":"2025","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":122,"file":[{"date_created":"2025-03-25T07:49:04Z","file_size":1553502,"file_id":"19454","content_type":"application/pdf","checksum":"1217207c254553154faa065964990988","creator":"dernst","access_level":"open_access","relation":"main_file","date_updated":"2025-03-25T07:49:04Z","file_name":"2025_PNAS_Chiossi.pdf","success":1}],"isi":1,"pmid":1,"date_published":"2025-03-10T00:00:00Z","day":"10","oa_version":"Published Version","abstract":[{"lang":"eng","text":"A key feature of biological and artificial neural networks is the progressive refinement of their neural representations with experience. In neuroscience, this fact has inspired several recent studies in sensory and motor systems. However, less is known about how higher associational cortical areas, such as the hippocampus, modify representations throughout the learning of complex tasks. Here, we focus on associative learning, a process that requires forming a connection between the representations of different variables for appropriate behavioral response. We trained rats in a space-context associative task and monitored hippocampal neural activity throughout the entire learning period, over several days. This allowed us to assess changes in the representations of context, movement direction, and position, as well as their relationship to behavior. We identified a hierarchical representational structure in the encoding of these three task variables that was preserved throughout learning. Nevertheless, we also observed changes at the lower levels of the hierarchy where context was encoded. These changes were local in neural activity space and restricted to physical positions where context identification was necessary for correct decision-making, supporting better context decoding and contextual code compression. Our results demonstrate that the hippocampal code not only accommodates hierarchical relationships between different variables but also enables efficient learning through minimal changes in neural activity space. Beyond the hippocampus, our work reveals a representation learning mechanism that might be implemented in other biological and artificial networks performing similar tasks."}],"type":"journal_article","doi":"10.1073/pnas.2417025122","month":"03","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"citation":{"ieee":"H. S. C. Chiossi, M. Nardin, G. Tkačik, and J. L. Csicsvari, “Learning reshapes the hippocampal representation hierarchy,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 11. National Academy of Sciences, 2025.","mla":"Chiossi, Heloisa S. C., et al. “Learning Reshapes the Hippocampal Representation Hierarchy.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 11, e2417025122, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2417025122\">10.1073/pnas.2417025122</a>.","ama":"Chiossi HSC, Nardin M, Tkačik G, Csicsvari JL. Learning reshapes the hippocampal representation hierarchy. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(11). doi:<a href=\"https://doi.org/10.1073/pnas.2417025122\">10.1073/pnas.2417025122</a>","short":"H.S.C. Chiossi, M. Nardin, G. Tkačik, J.L. Csicsvari, Proceedings of the National Academy of Sciences 122 (2025).","ista":"Chiossi HSC, Nardin M, Tkačik G, Csicsvari JL. 2025. Learning reshapes the hippocampal representation hierarchy. Proceedings of the National Academy of Sciences. 122(11), e2417025122.","apa":"Chiossi, H. S. C., Nardin, M., Tkačik, G., &#38; Csicsvari, J. L. (2025). Learning reshapes the hippocampal representation hierarchy. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2417025122\">https://doi.org/10.1073/pnas.2417025122</a>","chicago":"Chiossi, Heloisa S. C., Michele Nardin, Gašper Tkačik, and Jozsef L Csicsvari. “Learning Reshapes the Hippocampal Representation Hierarchy.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2417025122\">https://doi.org/10.1073/pnas.2417025122</a>."},"status":"public","OA_place":"publisher","quality_controlled":"1","title":"Learning reshapes the hippocampal representation hierarchy","APC_amount":"3317,75 EUR","external_id":{"pmid":["40063792"],"isi":["001459499500001"]},"article_type":"original","ddc":["570"],"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"date_updated":"2026-05-06T13:12:01Z","acknowledgement":"We would like to thank Rebecca Morse for performing the recordings in one of the animals under the supervision of H.S.C.C., Jago Wallenschus for the technical support, especially with maze design, Wiktor Mlynarski for the advice and discussions and Andrea Cumpelik for suggestions during the writing. M.N. was supported by the Howard Hughes Medical Institute. H.S.C.C. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 665385."},{"date_updated":"2025-09-30T11:20:36Z","article_type":"letter_note","external_id":{"pmid":["40155512"],"isi":["001455740100001"]},"title":"Understanding the machinery that reads the genome","quality_controlled":"1","status":"public","month":"06","publication_identifier":{"issn":["1471-0072"],"eissn":["1471-0080"]},"citation":{"ieee":"C. Bernecky, “Understanding the machinery that reads the genome,” <i>Nature Reviews Molecular Cell Biology</i>, vol. 26. Springer Nature, 2025.","mla":"Bernecky, Carrie. “Understanding the Machinery That Reads the Genome.” <i>Nature Reviews Molecular Cell Biology</i>, vol. 26, 415, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41580-025-00844-1\">10.1038/s41580-025-00844-1</a>.","short":"C. Bernecky, Nature Reviews Molecular Cell Biology 26 (2025).","ista":"Bernecky C. 2025. Understanding the machinery that reads the genome. Nature Reviews Molecular Cell Biology. 26, 415.","ama":"Bernecky C. Understanding the machinery that reads the genome. <i>Nature Reviews Molecular Cell Biology</i>. 2025;26. doi:<a href=\"https://doi.org/10.1038/s41580-025-00844-1\">10.1038/s41580-025-00844-1</a>","apa":"Bernecky, C. (2025). Understanding the machinery that reads the genome. <i>Nature Reviews Molecular Cell Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41580-025-00844-1\">https://doi.org/10.1038/s41580-025-00844-1</a>","chicago":"Bernecky, Carrie. “Understanding the Machinery That Reads the Genome.” <i>Nature Reviews Molecular Cell Biology</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41580-025-00844-1\">https://doi.org/10.1038/s41580-025-00844-1</a>."},"doi":"10.1038/s41580-025-00844-1","type":"journal_article","oa_version":"None","day":"01","isi":1,"pmid":1,"date_published":"2025-06-01T00:00:00Z","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":26,"year":"2025","publication_status":"published","OA_type":"closed access","corr_author":"1","intvolume":"        26","publication":"Nature Reviews Molecular Cell Biology","author":[{"id":"2CB9DFE2-F248-11E8-B48F-1D18A9856A87","first_name":"Carrie A","orcid":"0000-0003-0893-7036","full_name":"Bernecky, Carrie A","last_name":"Bernecky"}],"department":[{"_id":"CaBe"}],"article_number":"415","publisher":"Springer Nature","_id":"19465","language":[{"iso":"eng"}],"article_processing_charge":"No","scopus_import":"1","date_created":"2025-03-31T10:07:22Z"},{"OA_place":"publisher","quality_controlled":"1","status":"public","external_id":{"arxiv":["2408.15165"],"isi":["001453622900002"]},"title":"Latent Ewald summation for machine learning of long-range interactions","ddc":["000"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"original","acknowledgement":"B. C. thanks David Limmer for providing the water slab dataset, and Carolin Faller for the NaCl dataset.","date_updated":"2025-09-30T11:31:47Z","isi":1,"date_published":"2025-03-26T00:00:00Z","file":[{"date_created":"2025-04-08T09:34:58Z","file_size":1608315,"content_type":"application/pdf","file_id":"19528","access_level":"open_access","relation":"main_file","checksum":"cc99b7407a12139d9b2d8457961935ae","creator":"dernst","success":1,"file_name":"2025_npjCompMaterials_Cheng.pdf","date_updated":"2025-04-08T09:34:58Z"}],"oa_version":"Published Version","arxiv":1,"abstract":[{"lang":"eng","text":"Machine learning interatomic potentials (MLIPs) often neglect long-range interactions, such as electrostatic and dispersion forces. In this work, we introduce a straightforward and efficient method to account for long-range interactions by learning a hidden variable from local atomic descriptors and applying an Ewald summation to this variable. We demonstrate that in systems including charged and polar molecular dimers, bulk water, and water-vapor interface, standard short-ranged MLIPs can lead to unphysical predictions even when employing message passing. The long-range models effectively eliminate these artifacts, with only about twice the computational cost of short-range MLIPs."}],"DOAJ_listed":"1","day":"26","doi":"10.1038/s41524-025-01577-7","type":"journal_article","month":"03","publication_identifier":{"eissn":["2057-3960"]},"citation":{"ieee":"B. Cheng, “Latent Ewald summation for machine learning of long-range interactions,” <i>npj Computational Materials</i>, vol. 11. Springer Nature, 2025.","mla":"Cheng, Bingqing. “Latent Ewald Summation for Machine Learning of Long-Range Interactions.” <i>Npj Computational Materials</i>, vol. 11, 80, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41524-025-01577-7\">10.1038/s41524-025-01577-7</a>.","short":"B. Cheng, Npj Computational Materials 11 (2025).","ama":"Cheng B. Latent Ewald summation for machine learning of long-range interactions. <i>npj Computational Materials</i>. 2025;11. doi:<a href=\"https://doi.org/10.1038/s41524-025-01577-7\">10.1038/s41524-025-01577-7</a>","ista":"Cheng B. 2025. Latent Ewald summation for machine learning of long-range interactions. npj Computational Materials. 11, 80.","apa":"Cheng, B. (2025). Latent Ewald summation for machine learning of long-range interactions. <i>Npj Computational Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41524-025-01577-7\">https://doi.org/10.1038/s41524-025-01577-7</a>","chicago":"Cheng, Bingqing. “Latent Ewald Summation for Machine Learning of Long-Range Interactions.” <i>Npj Computational Materials</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41524-025-01577-7\">https://doi.org/10.1038/s41524-025-01577-7</a>."},"publication":"npj Computational Materials","corr_author":"1","intvolume":"        11","publication_status":"published","oa":1,"OA_type":"gold","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":11,"file_date_updated":"2025-04-08T09:34:58Z","year":"2025","article_processing_charge":"Yes","scopus_import":"1","date_created":"2025-04-06T22:01:32Z","publisher":"Springer Nature","_id":"19495","language":[{"iso":"eng"}],"department":[{"_id":"BiCh"}],"article_number":"80","author":[{"last_name":"Cheng","full_name":"Cheng, Bingqing","first_name":"Bingqing","id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","orcid":"0000-0002-3584-9632"}]},{"corr_author":"1","intvolume":"       310","publication":"Mathematische Zeitschrift","year":"2025","volume":310,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_type":"green","oa":1,"publication_status":"published","language":[{"iso":"eng"}],"_id":"19496","publisher":"Springer Nature","date_created":"2025-04-06T22:01:32Z","scopus_import":"1","article_processing_charge":"No","author":[{"full_name":"Helfter, Mathieu","last_name":"Helfter","id":"7d296fbe-e2c6-11ee-84d3-d5c2945f9a57","first_name":"Mathieu"}],"article_number":"15","department":[{"_id":"VaKa"}],"title":"Scales","external_id":{"isi":["001450830300001"],"arxiv":["2206.05231"]},"status":"public","quality_controlled":"1","OA_place":"repository","date_updated":"2025-09-30T11:31:00Z","article_type":"original","day":"01","arxiv":1,"abstract":[{"text":"We introduce the notions of scale for sets and measures on metric space by generalizing the usual notions of dimension. Several versions of scales are introduced such as Hausdorff, packing, box, local and quantization. They are defined for different growth, allowing a refined study of infinite dimensional spaces. We prove general theorems comparing the different versions of scales. They are applied to describe geometries of ergodic decompositions, of the Wiener measure and from functional spaces. The first application solves a problem of Berger on the notions of emergence (2020); the second lies in the geometry of the Wiener measure and extends the work of Dereich–Lifshits (2005); the last refines Kolmogorov–Tikhomirov (1958) study on finitely differentiable functions.","lang":"eng"}],"oa_version":"Preprint","date_published":"2025-05-01T00:00:00Z","isi":1,"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2206.05231","open_access":"1"}],"publication_identifier":{"issn":["0025-5874"],"eissn":["1432-1823"]},"citation":{"mla":"Helfter, Mathieu. “Scales.” <i>Mathematische Zeitschrift</i>, vol. 310, 15, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1007/s00209-025-03719-5\">10.1007/s00209-025-03719-5</a>.","ieee":"M. Helfter, “Scales,” <i>Mathematische Zeitschrift</i>, vol. 310. Springer Nature, 2025.","apa":"Helfter, M. (2025). Scales. <i>Mathematische Zeitschrift</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00209-025-03719-5\">https://doi.org/10.1007/s00209-025-03719-5</a>","chicago":"Helfter, Mathieu. “Scales.” <i>Mathematische Zeitschrift</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1007/s00209-025-03719-5\">https://doi.org/10.1007/s00209-025-03719-5</a>.","ama":"Helfter M. Scales. <i>Mathematische Zeitschrift</i>. 2025;310. doi:<a href=\"https://doi.org/10.1007/s00209-025-03719-5\">10.1007/s00209-025-03719-5</a>","ista":"Helfter M. 2025. Scales. Mathematische Zeitschrift. 310, 15.","short":"M. Helfter, Mathematische Zeitschrift 310 (2025)."},"month":"05","type":"journal_article","doi":"10.1007/s00209-025-03719-5"},{"language":[{"iso":"eng"}],"_id":"19497","publisher":"IOP Publishing","date_created":"2025-04-06T22:01:32Z","scopus_import":"1","article_processing_charge":"No","author":[{"last_name":"Kis-Tóth","full_name":"Kis-Tóth, Ágnes","first_name":"Ágnes"},{"id":"7c006e8c-cc0d-11ee-8322-cb904ef76f36","first_name":"Zoltán","orcid":"0000-0003-3633-5403","full_name":"Haiman, Zoltán","last_name":"Haiman"},{"first_name":"Zsolt","last_name":"Frei","full_name":"Frei, Zsolt"}],"article_number":"075007","department":[{"_id":"ZoHa"}],"intvolume":"        42","publication":"Classical and Quantum Gravity","issue":"7","year":"2025","volume":42,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","OA_type":"green","oa":1,"publication_status":"published","day":"04","oa_version":"Preprint","arxiv":1,"abstract":[{"text":"The stochastic gravitational wave (GW) background recently discovered by several pulsar timing array experiments is consistent with arising from a population of coalescing super-massive black hole binaries. The amplitude of the background is somewhat higher than expected in most previous population models or from the local mass density observations. Such binaries are expected to be produced in galaxy mergers, which are also thought to trigger bright quasar activity. Under the assumptions that (i) a fraction fbin∼1 of all quasars are associated with mergers, (ii) the typical quasar lifetime is tQ∼108 yr, and (iii) adopting Eddington ratios fEdd∼0.25 for the luminosity of quasars, we compute the GW background associated directly with the empirically measured quasar luminosity function. This approach bypasses the need to model the cosmological evolution of black holes or galaxy mergers from simulations or semi-analytical models. We find the amplitude matching the value measured by NANOGrav. Our results are consistent with most quasars being associated with black hole binaries and being the sources of the GW background, and imply a joint constraint on tQ, fEdd and the typical mass ratio q≡M2/M1. The signal in this case would be dominated by relatively distant ∼109M⊙ sources at z≈2−3, at the peak of quasar activity. Similarly to other models, our results remain in tension with the local super-massive black hole mass density.","lang":"eng"}],"date_published":"2025-04-04T00:00:00Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2412.12726"}],"isi":1,"publication_identifier":{"issn":["0264-9381"],"eissn":["1361-6382"]},"citation":{"apa":"Kis-Tóth, Á., Haiman, Z., &#38; Frei, Z. (2025). Can quasars, triggered by mergers, account for NANOGrav’s stochastic gravitational wave background? <i>Classical and Quantum Gravity</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1361-6382/adbda6\">https://doi.org/10.1088/1361-6382/adbda6</a>","chicago":"Kis-Tóth, Ágnes, Zoltán Haiman, and Zsolt Frei. “Can Quasars, Triggered by Mergers, Account for NANOGrav’s Stochastic Gravitational Wave Background?” <i>Classical and Quantum Gravity</i>. IOP Publishing, 2025. <a href=\"https://doi.org/10.1088/1361-6382/adbda6\">https://doi.org/10.1088/1361-6382/adbda6</a>.","ista":"Kis-Tóth Á, Haiman Z, Frei Z. 2025. Can quasars, triggered by mergers, account for NANOGrav’s stochastic gravitational wave background? Classical and Quantum Gravity. 42(7), 075007.","short":"Á. Kis-Tóth, Z. Haiman, Z. Frei, Classical and Quantum Gravity 42 (2025).","ama":"Kis-Tóth Á, Haiman Z, Frei Z. Can quasars, triggered by mergers, account for NANOGrav’s stochastic gravitational wave background? <i>Classical and Quantum Gravity</i>. 2025;42(7). doi:<a href=\"https://doi.org/10.1088/1361-6382/adbda6\">10.1088/1361-6382/adbda6</a>","mla":"Kis-Tóth, Ágnes, et al. “Can Quasars, Triggered by Mergers, Account for NANOGrav’s Stochastic Gravitational Wave Background?” <i>Classical and Quantum Gravity</i>, vol. 42, no. 7, 075007, IOP Publishing, 2025, doi:<a href=\"https://doi.org/10.1088/1361-6382/adbda6\">10.1088/1361-6382/adbda6</a>.","ieee":"Á. Kis-Tóth, Z. Haiman, and Z. Frei, “Can quasars, triggered by mergers, account for NANOGrav’s stochastic gravitational wave background?,” <i>Classical and Quantum Gravity</i>, vol. 42, no. 7. IOP Publishing, 2025."},"month":"04","doi":"10.1088/1361-6382/adbda6","type":"journal_article","title":"Can quasars, triggered by mergers, account for NANOGrav’s stochastic gravitational wave background?","external_id":{"isi":["001448904700001"],"arxiv":["2412.12726"]},"status":"public","quality_controlled":"1","OA_place":"repository","date_updated":"2025-09-30T11:30:11Z","acknowledgement":"We thank Chengcheng Xin and Girish Kulkarni for useful discussions. ZH gratefully acknowledges the hospitality of Eötvös University during an extended sabbatical visit, where this work began. ZH acknowledges support from NSF Grant AST-2006176 and NASA Grants 80NSSC22K0822 and 80NSSC24K0440. ZF acknowledges support from the Hungarian National Research, Development and Innovation Office (NKFIH) through the Institutional Excellence Program No. TKP2021-NKTA-64.","article_type":"original"},{"status":"public","quality_controlled":"1","OA_place":"publisher","title":"Hardware-optimal quantum algorithms","external_id":{"pmid":["40106357"],"isi":["001459435600001"]},"article_type":"original","tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"ddc":["000"],"date_updated":"2026-04-28T13:41:14Z","acknowledgement":"We thank the reviewers. In particular, they inspired us to analyze the reset and state-preparation problems, to compute optimal qubit mappings, and to apply our method to a quantum error correction scheme that includes both bitflip and phaseflip corrections. We also thank Raimundo Saona and Marek Chalupa for their time spent in insightful discussions. This research was partially supported by the European Research Council CoG 863818 (ForM-SMArt) grant.","file":[{"date_updated":"2025-04-07T11:42:22Z","file_name":"2025_PNAS_Muroya.pdf","success":1,"checksum":"83501b8a65ee5fdd3f5604fc28eddc22","creator":"dernst","access_level":"open_access","relation":"main_file","file_id":"19524","content_type":"application/pdf","file_size":6805668,"date_created":"2025-04-07T11:42:22Z"}],"date_published":"2025-03-25T00:00:00Z","pmid":1,"isi":1,"day":"25","abstract":[{"lang":"eng","text":"Quantum hardware is inherently fragile and noisy. We find that the accuracy of traditional quantum error correction algorithms can be improved depending on the hardware. Given different hardware specifications, we automatically synthesize hardware-optimal algorithms for parity correction, qubit resetting, and GHZ (Greenberger–Horne–Zeilinger) state preparation. Using stochastic techniques from computer science, our method presents a computational tool to compute exact accuracy guarantees and synthesize optimal algorithms that are often different from traditional ones. We also show that improvements can be gained with respect to the Qiskit transpiler as we compute the hardware-optimal qubit mapping for the GHZ state-preparation problem."}],"oa_version":"Published Version","doi":"10.1073/pnas.2419273122","type":"journal_article","citation":{"ama":"Muroya Lei S, Chatterjee K, Henzinger TA. Hardware-optimal quantum algorithms. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(12). doi:<a href=\"https://doi.org/10.1073/pnas.2419273122\">10.1073/pnas.2419273122</a>","short":"S. Muroya Lei, K. Chatterjee, T.A. Henzinger, Proceedings of the National Academy of Sciences 122 (2025).","ista":"Muroya Lei S, Chatterjee K, Henzinger TA. 2025. Hardware-optimal quantum algorithms. Proceedings of the National Academy of Sciences. 122(12), e2419273122.","apa":"Muroya Lei, S., Chatterjee, K., &#38; Henzinger, T. A. (2025). Hardware-optimal quantum algorithms. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2419273122\">https://doi.org/10.1073/pnas.2419273122</a>","chicago":"Muroya Lei, Stefanie, Krishnendu Chatterjee, and Thomas A Henzinger. “Hardware-Optimal Quantum Algorithms.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2419273122\">https://doi.org/10.1073/pnas.2419273122</a>.","ieee":"S. Muroya Lei, K. Chatterjee, and T. A. Henzinger, “Hardware-optimal quantum algorithms,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 12. National Academy of Sciences, 2025.","mla":"Muroya Lei, Stefanie, et al. “Hardware-Optimal Quantum Algorithms.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 12, e2419273122, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2419273122\">10.1073/pnas.2419273122</a>."},"publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"month":"03","publication":"Proceedings of the National Academy of Sciences","issue":"12","corr_author":"1","intvolume":"       122","OA_type":"hybrid","has_accepted_license":"1","oa":1,"ec_funded":1,"publication_status":"published","year":"2025","file_date_updated":"2025-04-07T11:42:22Z","volume":122,"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2025-04-06T22:01:32Z","related_material":{"link":[{"url":"https://github.com/smml1996/algorithm_synthesis","relation":"software"},{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/hardware-optimal-quantum-algorithms/"}]},"scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","language":[{"iso":"eng"}],"_id":"19499","publisher":"National Academy of Sciences","article_number":"e2419273122","project":[{"_id":"0599E47C-7A3F-11EA-A408-12923DDC885E","call_identifier":"H2020","grant_number":"863818","name":"Formal Methods for Stochastic Models: Algorithms and Applications"}],"department":[{"_id":"KrCh"},{"_id":"ToHe"}],"author":[{"id":"a376de31-8972-11ed-ae7b-d0251c13c8ff","first_name":"Stefanie","last_name":"Muroya Lei","full_name":"Muroya Lei, Stefanie"},{"last_name":"Chatterjee","full_name":"Chatterjee, Krishnendu","orcid":"0000-0002-4561-241X","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","first_name":"Krishnendu"},{"id":"40876CD8-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas A","orcid":"0000-0002-2985-7724","last_name":"Henzinger","full_name":"Henzinger, Thomas A"}]},{"file_date_updated":"2025-04-07T11:21:13Z","year":"2025","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":30,"oa":1,"has_accepted_license":"1","OA_type":"gold","publication_status":"published","ec_funded":1,"intvolume":"        30","corr_author":"1","publication":"Documenta Mathematica","issue":"2","author":[{"orcid":"0000-0001-5366-9603","first_name":"László","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","full_name":"Erdös, László","last_name":"Erdös"},{"first_name":"Hong Chang","full_name":"Ji, Hong Chang","last_name":"Ji"}],"department":[{"_id":"LaEr"}],"project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","grant_number":"101020331","call_identifier":"H2020","name":"Random matrices beyond Wigner-Dyson-Mehta"}],"language":[{"iso":"eng"}],"_id":"19500","publisher":"EMS Press","date_created":"2025-04-06T22:01:32Z","article_processing_charge":"Yes","scopus_import":"1","date_updated":"2025-09-30T11:28:02Z","acknowledgement":"We thank Ping Zhong for pointing out references [15,19] and providing helpful comments. We also thank the anonymous referee for many valuable comments and proposals to streamline the presentation. This work was partially supported by ERC Advanced Grant “RMTBeyond” No. 10102033.","article_type":"original","ddc":["510"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Density of Brown measure of free circular Brownian motion","page":"417-453","external_id":{"arxiv":["2307.08626"],"isi":["001450119900005"]},"status":"public","OA_place":"publisher","quality_controlled":"1","month":"03","publication_identifier":{"issn":["1431-0635"],"eissn":["1431-0643"]},"citation":{"mla":"Erdös, László, and Hong Chang Ji. “Density of Brown Measure of Free Circular Brownian Motion.” <i>Documenta Mathematica</i>, vol. 30, no. 2, EMS Press, 2025, pp. 417–53, doi:<a href=\"https://doi.org/10.4171/DM/999\">10.4171/DM/999</a>.","ieee":"L. Erdös and H. C. Ji, “Density of Brown measure of free circular Brownian motion,” <i>Documenta Mathematica</i>, vol. 30, no. 2. EMS Press, pp. 417–453, 2025.","chicago":"Erdös, László, and Hong Chang Ji. “Density of Brown Measure of Free Circular Brownian Motion.” <i>Documenta Mathematica</i>. EMS Press, 2025. <a href=\"https://doi.org/10.4171/DM/999\">https://doi.org/10.4171/DM/999</a>.","apa":"Erdös, L., &#38; Ji, H. C. (2025). Density of Brown measure of free circular Brownian motion. <i>Documenta Mathematica</i>. EMS Press. <a href=\"https://doi.org/10.4171/DM/999\">https://doi.org/10.4171/DM/999</a>","short":"L. Erdös, H.C. Ji, Documenta Mathematica 30 (2025) 417–453.","ama":"Erdös L, Ji HC. Density of Brown measure of free circular Brownian motion. <i>Documenta Mathematica</i>. 2025;30(2):417-453. doi:<a href=\"https://doi.org/10.4171/DM/999\">10.4171/DM/999</a>","ista":"Erdös L, Ji HC. 2025. Density of Brown measure of free circular Brownian motion. Documenta Mathematica. 30(2), 417–453."},"type":"journal_article","doi":"10.4171/DM/999","day":"20","arxiv":1,"oa_version":"Published Version","abstract":[{"text":"We consider the Brown measure of the free circular Brownian motion,  a+t√x , with an arbitrary initial condition  a , i.e.  a  is a general non-normal operator and  x  is a circular element  ∗ -free from  a . We prove that, under a mild assumption on  a , the density of the Brown measure has one of the following two types of behavior around each point on the boundary of its support -- either (i) sharp cut, i.e. a jump discontinuity along the boundary, or (ii) quadratic decay at certain critical points on the boundary. Our result is in direct analogy with the previously known phenomenon for the spectral density of free semicircular Brownian motion, whose singularities are either a square-root edge or a cubic cusp. We also provide several examples and counterexamples, one of which shows that our assumption on  a  is necessary.","lang":"eng"}],"DOAJ_listed":"1","file":[{"creator":"dernst","checksum":"97a02d18c05f2b9f2048747b140e7d43","relation":"main_file","access_level":"open_access","date_updated":"2025-04-07T11:21:13Z","file_name":"2025_DocumentaMathematica_Erdoes.pdf","success":1,"file_size":1366865,"date_created":"2025-04-07T11:21:13Z","file_id":"19523","content_type":"application/pdf"}],"isi":1,"date_published":"2025-03-20T00:00:00Z"},{"article_number":"033114","department":[{"_id":"MiLe"}],"author":[{"full_name":"Kristensen, Henrik H.","last_name":"Kristensen","first_name":"Henrik H."},{"first_name":"Lorenz","full_name":"Kranabetter, Lorenz","last_name":"Kranabetter"},{"orcid":"0000-0001-9666-3543","first_name":"Areg","id":"4AF46FD6-F248-11E8-B48F-1D18A9856A87","full_name":"Ghazaryan, Areg","last_name":"Ghazaryan"},{"first_name":"Constant A.","full_name":"Schouder, Constant A.","last_name":"Schouder"},{"full_name":"Hansen, Emil","last_name":"Hansen","first_name":"Emil"},{"first_name":"Frank","last_name":"Jensen","full_name":"Jensen, Frank"},{"full_name":"Zillich, Robert E.","last_name":"Zillich","first_name":"Robert E."},{"last_name":"Lemeshko","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","first_name":"Mikhail"},{"first_name":"Henrik","full_name":"Stapelfeldt, Henrik","last_name":"Stapelfeldt"}],"date_created":"2025-04-06T22:01:32Z","article_processing_charge":"No","scopus_import":"1","_id":"19502","language":[{"iso":"eng"}],"publisher":"American Physical Society","oa":1,"OA_type":"green","publication_status":"published","year":"2025","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":111,"publication":"Physical Review A","issue":"3","intvolume":"       111","type":"journal_article","doi":"10.1103/PhysRevA.111.033114","month":"03","citation":{"chicago":"Kristensen, Henrik H., Lorenz Kranabetter, Areg Ghazaryan, Constant A. Schouder, Emil Hansen, Frank Jensen, Robert E. Zillich, Mikhail Lemeshko, and Henrik Stapelfeldt. “Nonadiabatic Laser-Induced Alignment Dynamics of Alkali-Metal Dimers on the Surface of a Helium Droplet.” <i>Physical Review A</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/PhysRevA.111.033114\">https://doi.org/10.1103/PhysRevA.111.033114</a>.","apa":"Kristensen, H. H., Kranabetter, L., Ghazaryan, A., Schouder, C. A., Hansen, E., Jensen, F., … Stapelfeldt, H. (2025). Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. <i>Physical Review A</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevA.111.033114\">https://doi.org/10.1103/PhysRevA.111.033114</a>","short":"H.H. Kristensen, L. Kranabetter, A. Ghazaryan, C.A. Schouder, E. Hansen, F. Jensen, R.E. Zillich, M. Lemeshko, H. Stapelfeldt, Physical Review A 111 (2025).","ista":"Kristensen HH, Kranabetter L, Ghazaryan A, Schouder CA, Hansen E, Jensen F, Zillich RE, Lemeshko M, Stapelfeldt H. 2025. Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. Physical Review A. 111(3), 033114.","ama":"Kristensen HH, Kranabetter L, Ghazaryan A, et al. Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet. <i>Physical Review A</i>. 2025;111(3). doi:<a href=\"https://doi.org/10.1103/PhysRevA.111.033114\">10.1103/PhysRevA.111.033114</a>","mla":"Kristensen, Henrik H., et al. “Nonadiabatic Laser-Induced Alignment Dynamics of Alkali-Metal Dimers on the Surface of a Helium Droplet.” <i>Physical Review A</i>, vol. 111, no. 3, 033114, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/PhysRevA.111.033114\">10.1103/PhysRevA.111.033114</a>.","ieee":"H. H. Kristensen <i>et al.</i>, “Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet,” <i>Physical Review A</i>, vol. 111, no. 3. American Physical Society, 2025."},"publication_identifier":{"eissn":["2469-9934"],"issn":["2469-9926"]},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2502.14521","open_access":"1"}],"isi":1,"date_published":"2025-03-21T00:00:00Z","day":"21","arxiv":1,"oa_version":"Preprint","abstract":[{"lang":"eng","text":"Alkali dimers, Ak2, located on the surface of a helium nanodroplet, are set into rotation through the polarizability interaction with a nonresonant 1-ps-long laser pulse. The time-dependent degree of alignment is recorded using femtosecond-probe-pulse-induced Coulomb explosion into a pair of Ak+ fragment ions. The results, obtained for Na2, K2, and Rb2 in both the ground state 11Σ+g and the lowest-lying triplet state 13Σ+u, exhibit distinct, periodic revivals with a gradually decreasing amplitude. The dynamics differ from that expected for dimers had they behaved as free rotors. Numerically, we solve the time-dependent rotational Schrödinger equation, including an effective mean-field potential to describe the interaction between the dimer and the droplet. The experimental and simulated alignment dynamics agree well and their comparison enables us to determine the effective rotational constants of the alkali dimers with the exception of Rb2(13Σ+u) that only exhibits a prompt alignment peak but no subsequent revivals. For Na2(13Σ+u), K2(11Σ+g), K2(13Σ+u) and Rb2(11Σ+g), the alignment dynamics are well-described by a 2D rotor model. We ascribe this to a significant confinement of the internuclear axis of these dimers, induced by the orientation-dependent droplet-dimer interaction, to the tangential plane of their residence point on the droplet."}],"article_type":"original","date_updated":"2025-09-30T11:27:25Z","acknowledgement":"H.S. acknowledges support from the Villum Foundation through a Villum Investigator Grant No. 25886. We thank Jan Thøgersen for expert help with the optics and the laser system.","status":"public","OA_place":"repository","quality_controlled":"1","title":"Nonadiabatic laser-induced alignment dynamics of alkali-metal dimers on the surface of a helium droplet","external_id":{"isi":["001459727400007"],"arxiv":["2502.14521"]}},{"intvolume":"        34","issue":"4","publication":"Combinatorics Probability and Computing","volume":34,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2025","file_date_updated":"2025-08-05T12:54:06Z","ec_funded":1,"publication_status":"published","OA_type":"hybrid","has_accepted_license":"1","oa":1,"publisher":"Cambridge University Press","language":[{"iso":"eng"}],"_id":"19503","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","date_created":"2025-04-06T22:01:32Z","author":[{"first_name":"Micha","last_name":"Christoph","full_name":"Christoph, Micha"},{"id":"554ff4e4-f325-11ee-b0c4-a10dbd523381","first_name":"Kalina H","last_name":"Petrova","full_name":"Petrova, Kalina H"},{"last_name":"Steiner","full_name":"Steiner, Raphael","first_name":"Raphael"}],"project":[{"call_identifier":"H2020","grant_number":"101034413","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program"}],"department":[{"_id":"MaKw"}],"external_id":{"isi":["001449245700001"],"arxiv":["2310.08449"]},"page":"559-564","title":"A note on digraph splitting","quality_controlled":"1","OA_place":"publisher","status":"public","acknowledgement":"Funded by SNSF Ambizione grant No. 216071. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No, 101034413. Funded by SNSF grant CRSII5, 173721.","date_updated":"2025-09-30T11:26:00Z","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"ddc":["510"],"article_type":"original","abstract":[{"lang":"eng","text":"A tantalizing open problem, posed independently by Stiebitz in 1995 and by Alon in 1996 and again in 2006, asks whether for every pair of integers  s,t≥1 there exists a finite number  F(s,t)\r\nsuch that the vertex set of every digraph of minimum out-degree at least  F(s,t) can be partitioned into non-empty parts  A  and  B  such that the subdigraphs induced on  A\r\n  and  B  have minimum out-degree at least  s  and  t , respectively.\r\nIn this short note, we prove that if  F(2,2)  exists, then all the numbers  F(s,t)  with  s,t≥1\r\n  exist and satisfy  F(s,t)=Θ(s+t) . In consequence, the problem of Alon and Stiebitz reduces to the case  s=t=2 . Moreover, the numbers  F(s,t)  with  s,t≥2  either all exist and grow linearly, or all of them do not exist."}],"arxiv":1,"oa_version":"Published Version","day":"01","date_published":"2025-07-01T00:00:00Z","isi":1,"file":[{"file_name":"2025_CombProbComputing_Christoph.pdf","success":1,"date_updated":"2025-08-05T12:54:06Z","access_level":"open_access","relation":"main_file","checksum":"98491e59b4f0d05d69f608bbd5706f1a","creator":"dernst","content_type":"application/pdf","file_id":"20135","date_created":"2025-08-05T12:54:06Z","file_size":188818}],"citation":{"short":"M. Christoph, K.H. Petrova, R. Steiner, Combinatorics Probability and Computing 34 (2025) 559–564.","ama":"Christoph M, Petrova KH, Steiner R. A note on digraph splitting. <i>Combinatorics Probability and Computing</i>. 2025;34(4):559-564. doi:<a href=\"https://doi.org/10.1017/S0963548325000045\">10.1017/S0963548325000045</a>","ista":"Christoph M, Petrova KH, Steiner R. 2025. A note on digraph splitting. Combinatorics Probability and Computing. 34(4), 559–564.","chicago":"Christoph, Micha, Kalina H Petrova, and Raphael Steiner. “A Note on Digraph Splitting.” <i>Combinatorics Probability and Computing</i>. Cambridge University Press, 2025. <a href=\"https://doi.org/10.1017/S0963548325000045\">https://doi.org/10.1017/S0963548325000045</a>.","apa":"Christoph, M., Petrova, K. H., &#38; Steiner, R. (2025). A note on digraph splitting. <i>Combinatorics Probability and Computing</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/S0963548325000045\">https://doi.org/10.1017/S0963548325000045</a>","ieee":"M. Christoph, K. H. Petrova, and R. Steiner, “A note on digraph splitting,” <i>Combinatorics Probability and Computing</i>, vol. 34, no. 4. Cambridge University Press, pp. 559–564, 2025.","mla":"Christoph, Micha, et al. “A Note on Digraph Splitting.” <i>Combinatorics Probability and Computing</i>, vol. 34, no. 4, Cambridge University Press, 2025, pp. 559–64, doi:<a href=\"https://doi.org/10.1017/S0963548325000045\">10.1017/S0963548325000045</a>."},"publication_identifier":{"eissn":["1469-2163"],"issn":["0963-5483"]},"month":"07","type":"journal_article","doi":"10.1017/S0963548325000045"},{"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"ddc":["520"],"article_type":"original","acknowledgement":"We thank B. Wang, P. Madau, M. Dotti, A. de la Vega, Y. Guo, C. Bacchini, Z. Cai, C. Conselice, A. Dekel, S. Faber, F. Fraternali, L. Ho, F. Jiang, S. Kassin, D. Koo, N. Mandelker, S. Mao and D. Xu for the valuable and insightful discussions regarding the research topics relevant to this paper. This project was supported by the European Research Council (ERC) Consolidator Grant no. 864361 (CosmicWeb). A.P. acknowledges the support from Fondazione Cariplo grant no. 2020-0902. M.V.M. acknowledges funding from NASA by means of HST-GO-17065. T.N. acknowledges support from Australian Research Council Laureate Fellowship FL180100060. This work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with programme no. 1835. Support for programme no. 1835 was provided by NASA through a grant from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127. This research is based on observations made with the NASA/ESA Hubble Space Telescope obtained from the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555. These observations are associated with programme 17065. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada), MOST and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. The scientific results reported in this article are based in part on observations made by the Chandra X-ray Observatory. This work is also based on observations collected at the European Southern Observatory under ESO programme 110.23ZX.","date_updated":"2025-09-30T11:25:14Z","quality_controlled":"1","OA_place":"publisher","status":"public","external_id":{"arxiv":["2409.17956"],"pmid":["40417329"],"isi":["001447477100001"]},"page":"710-719","title":"A giant disk galaxy two billion years after the Big Bang","type":"journal_article","doi":"10.1038/s41550-025-02500-2","publication_identifier":{"eissn":["2397-3366"]},"citation":{"ama":"Wang W, Cantalupo S, Pensabene A, et al. A giant disk galaxy two billion years after the Big Bang. <i>Nature Astronomy</i>. 2025;9:710-719. doi:<a href=\"https://doi.org/10.1038/s41550-025-02500-2\">10.1038/s41550-025-02500-2</a>","ista":"Wang W, Cantalupo S, Pensabene A, Galbiati M, Travascio A, Steidel CC, Maseda MV, Pezzulli G, De Beer S, Fossati M, Fumagalli M, Gallego SG, Lazeyras T, Mackenzie R, Matthee JJ, Nanayakkara T, Quadri G. 2025. A giant disk galaxy two billion years after the Big Bang. Nature Astronomy. 9, 710–719.","short":"W. Wang, S. Cantalupo, A. Pensabene, M. Galbiati, A. Travascio, C.C. Steidel, M.V. Maseda, G. Pezzulli, S. De Beer, M. Fossati, M. Fumagalli, S.G. Gallego, T. Lazeyras, R. Mackenzie, J.J. Matthee, T. Nanayakkara, G. Quadri, Nature Astronomy 9 (2025) 710–719.","apa":"Wang, W., Cantalupo, S., Pensabene, A., Galbiati, M., Travascio, A., Steidel, C. C., … Quadri, G. (2025). A giant disk galaxy two billion years after the Big Bang. <i>Nature Astronomy</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41550-025-02500-2\">https://doi.org/10.1038/s41550-025-02500-2</a>","chicago":"Wang, Weichen, Sebastiano Cantalupo, Antonio Pensabene, Marta Galbiati, Andrea Travascio, Charles C. Steidel, Michael V. Maseda, et al. “A Giant Disk Galaxy Two Billion Years after the Big Bang.” <i>Nature Astronomy</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41550-025-02500-2\">https://doi.org/10.1038/s41550-025-02500-2</a>.","ieee":"W. Wang <i>et al.</i>, “A giant disk galaxy two billion years after the Big Bang,” <i>Nature Astronomy</i>, vol. 9. Springer Nature, pp. 710–719, 2025.","mla":"Wang, Weichen, et al. “A Giant Disk Galaxy Two Billion Years after the Big Bang.” <i>Nature Astronomy</i>, vol. 9, Springer Nature, 2025, pp. 710–19, doi:<a href=\"https://doi.org/10.1038/s41550-025-02500-2\">10.1038/s41550-025-02500-2</a>."},"month":"03","date_published":"2025-03-17T00:00:00Z","pmid":1,"isi":1,"file":[{"access_level":"open_access","relation":"main_file","checksum":"a0e65fe3374bd755b18ba03fd5e42a3f","creator":"dernst","file_name":"2025_NatureAstronomy_Wang.pdf","success":1,"date_updated":"2025-08-05T12:49:36Z","date_created":"2025-08-05T12:49:36Z","file_size":4912850,"content_type":"application/pdf","file_id":"20134"}],"abstract":[{"text":"Observational studies have shown that galaxy disks were already in place in the first few billion years of the Universe. The early disks detected so far, with typical half-light radii of 3 kpc at stellar masses around 1011 M⊙ for redshift z ≈ 3, are significantly smaller than today’s disks with similar masses, which is in agreement with expectations from current galaxy models. Here we report observations of a giant disk at z = 3.25, when the Universe was only two billion years old, with a half-light radius of 9.6 kpc and stellar mass of (math formular). This galaxy is larger than any other kinematically confirmed disks at similar epochs and is surprisingly similar to today’s largest disks with regard to size and mass. James Webb Space Telescope imaging and spectroscopy reveal its spiral morphology and a rotational velocity consistent with a local Tully–Fisher relationship. Multiwavelength observations show that it lies in an exceptionally dense environment, where the galaxy number density is more than ten times higher than the cosmic average and mergers are frequent. The discovery of such a giant disk suggests the presence of favourable physical conditions for large-disk formation in dense environments in the early Universe, which may include efficient accretion of gas carrying coherent angular momentum and non-destructive mergers between exceptionally gas-rich progenitor galaxies.","lang":"eng"}],"oa_version":"Published Version","arxiv":1,"day":"17","publication_status":"published","has_accepted_license":"1","OA_type":"hybrid","oa":1,"volume":9,"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2025","file_date_updated":"2025-08-05T12:49:36Z","publication":"Nature Astronomy","intvolume":"         9","department":[{"_id":"JoMa"}],"author":[{"first_name":"Weichen","last_name":"Wang","full_name":"Wang, Weichen"},{"last_name":"Cantalupo","full_name":"Cantalupo, Sebastiano","first_name":"Sebastiano"},{"last_name":"Pensabene","full_name":"Pensabene, Antonio","first_name":"Antonio"},{"full_name":"Galbiati, Marta","last_name":"Galbiati","first_name":"Marta"},{"full_name":"Travascio, Andrea","last_name":"Travascio","first_name":"Andrea"},{"full_name":"Steidel, Charles C.","last_name":"Steidel","first_name":"Charles C."},{"full_name":"Maseda, Michael V.","last_name":"Maseda","first_name":"Michael V."},{"first_name":"Gabriele","full_name":"Pezzulli, Gabriele","last_name":"Pezzulli"},{"first_name":"Stephanie","last_name":"De Beer","full_name":"De Beer, Stephanie"},{"last_name":"Fossati","full_name":"Fossati, Matteo","first_name":"Matteo"},{"first_name":"Michele","last_name":"Fumagalli","full_name":"Fumagalli, Michele"},{"first_name":"Sofia G.","full_name":"Gallego, Sofia G.","last_name":"Gallego"},{"last_name":"Lazeyras","full_name":"Lazeyras, Titouan","first_name":"Titouan"},{"first_name":"Ruari","full_name":"Mackenzie, Ruari","last_name":"Mackenzie"},{"full_name":"Matthee, Jorryt J","last_name":"Matthee","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","orcid":"0000-0003-2871-127X"},{"first_name":"Themiya","full_name":"Nanayakkara, Themiya","last_name":"Nanayakkara"},{"last_name":"Quadri","full_name":"Quadri, Giada","first_name":"Giada"}],"scopus_import":"1","article_processing_charge":"No","date_created":"2025-04-06T22:01:32Z","publisher":"Springer Nature","_id":"19504","language":[{"iso":"eng"}]},{"intvolume":"        35","issue":"1","publication":"Annals of Applied Probability","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","volume":35,"year":"2025","publication_status":"published","ec_funded":1,"oa":1,"OA_type":"green","publisher":"Institute of Mathematical Statistics","_id":"19505","language":[{"iso":"eng"}],"article_processing_charge":"No","scopus_import":"1","date_created":"2025-04-06T22:01:32Z","author":[{"full_name":"Agresti, Antonio","last_name":"Agresti","orcid":"0000-0002-9573-2962","first_name":"Antonio","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72"},{"first_name":"Matthias","full_name":"Hieber, Matthias","last_name":"Hieber"},{"first_name":"Amru","last_name":"Hussein","full_name":"Hussein, Amru"},{"first_name":"Martin","last_name":"Saal","full_name":"Saal, Martin"}],"department":[{"_id":"JuFi"}],"project":[{"call_identifier":"H2020","grant_number":"948819","_id":"0aa76401-070f-11eb-9043-b5bb049fa26d","name":"Bridging Scales in Random Materials"}],"page":"635-700","external_id":{"arxiv":["2210.05973"],"isi":["001434322900016"]},"title":"The stochastic primitive equations with nonisothermal turbulent pressure","OA_place":"repository","quality_controlled":"1","status":"public","acknowledgement":"The first author thanks Umberto Pappalettera for helpful suggestions on Section 2 and for bringing to his attention the reference [56]. The first author is grateful to Marco Romito for helpful comments related to Remarks 2.1 and 2.2. Finally, the first author thanks Caterina Balzotti for her support in creating the picture.\r\nAntonio Agresti has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 948819). Antonio Agresti is a member of GNAMPA (INδAM).\r\nMatthias Hieber gratefully acknowledges the support by the Deutsche Forschungsgemeinschaft (DFG) through the Research Unit 5528—project number 500072446.\r\nAmru Hussein has been supported by Deutsche Forschungsgemeinschaft (DFG)—project\r\nnumber 508634462 and by MathApp—Mathematics Applied to Real-World Problems—part\r\nof the Research Initiative of the Federal State of Rhineland-Palatinate, Germany.\r\nMartin Saal has been supported by Deutsche Forschungsgemeinschaft (DFG)—project\r\nnumber 429483464.","date_updated":"2025-09-30T11:23:58Z","article_type":"original","oa_version":"Preprint","abstract":[{"text":"In this paper, we introduce and study the primitive equations with non-isothermal turbulent pressure and transport noise. They are derived from the Navier–Stokes equations by employing stochastic versions of the Boussinesq and the hydrostatic approximations. The temperature dependence of the turbulent pressure can be seen as a consequence of an additive noise acting on the small vertical dynamics. For such a model we prove global well-posedness in H^1 where the noise is considered in both the Itô and Stratonovich formulations. Compared to previous variants of the primitive equations, the one considered here presents a more intricate coupling between the velocity field and the temperature. The corresponding analysis is seriously more involved than in the deterministic setting. Finally, the continuous dependence on the initial data and the energy estimates proven here are new, even in the case of isothermal turbulent pressure.","lang":"eng"}],"arxiv":1,"day":"01","isi":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2210.05973"}],"date_published":"2025-02-01T00:00:00Z","month":"02","citation":{"ieee":"A. Agresti, M. Hieber, A. Hussein, and M. Saal, “The stochastic primitive equations with nonisothermal turbulent pressure,” <i>Annals of Applied Probability</i>, vol. 35, no. 1. Institute of Mathematical Statistics, pp. 635–700, 2025.","mla":"Agresti, Antonio, et al. “The Stochastic Primitive Equations with Nonisothermal Turbulent Pressure.” <i>Annals of Applied Probability</i>, vol. 35, no. 1, Institute of Mathematical Statistics, 2025, pp. 635–700, doi:<a href=\"https://doi.org/10.1214/24-AAP2124\">10.1214/24-AAP2124</a>.","ista":"Agresti A, Hieber M, Hussein A, Saal M. 2025. The stochastic primitive equations with nonisothermal turbulent pressure. Annals of Applied Probability. 35(1), 635–700.","short":"A. Agresti, M. Hieber, A. Hussein, M. Saal, Annals of Applied Probability 35 (2025) 635–700.","ama":"Agresti A, Hieber M, Hussein A, Saal M. The stochastic primitive equations with nonisothermal turbulent pressure. <i>Annals of Applied Probability</i>. 2025;35(1):635-700. doi:<a href=\"https://doi.org/10.1214/24-AAP2124\">10.1214/24-AAP2124</a>","apa":"Agresti, A., Hieber, M., Hussein, A., &#38; Saal, M. (2025). The stochastic primitive equations with nonisothermal turbulent pressure. <i>Annals of Applied Probability</i>. Institute of Mathematical Statistics. <a href=\"https://doi.org/10.1214/24-AAP2124\">https://doi.org/10.1214/24-AAP2124</a>","chicago":"Agresti, Antonio, Matthias Hieber, Amru Hussein, and Martin Saal. “The Stochastic Primitive Equations with Nonisothermal Turbulent Pressure.” <i>Annals of Applied Probability</i>. Institute of Mathematical Statistics, 2025. <a href=\"https://doi.org/10.1214/24-AAP2124\">https://doi.org/10.1214/24-AAP2124</a>."},"publication_identifier":{"issn":["1050-5164"]},"type":"journal_article","doi":"10.1214/24-AAP2124"},{"publisher":"Elsevier","_id":"19506","language":[{"iso":"eng"}],"article_processing_charge":"Yes (via OA deal)","scopus_import":"1","related_material":{"link":[{"description":"News on ISTA website","relation":"press_release","url":"https://ista.ac.at/en/news/how-sleep-keeps-our-memories-fresh/"}]},"date_created":"2025-04-06T22:01:32Z","author":[{"last_name":"Bollmann","full_name":"Bollmann, Lars","first_name":"Lars","id":"47AD3038-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Peter","id":"361CC00E-F248-11E8-B48F-1D18A9856A87","last_name":"Baracskay","full_name":"Baracskay, Peter"},{"full_name":"Stella, Federico","last_name":"Stella","first_name":"Federico","id":"39AF1E74-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9439-3148"},{"full_name":"Csicsvari, Jozsef L","last_name":"Csicsvari","orcid":"0000-0002-5193-4036","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","first_name":"Jozsef L"}],"department":[{"_id":"JoCs"}],"project":[{"name":"Memory-related information processing in neuronal circuits of the hippocampus and entorhinal cortex","_id":"257A4776-B435-11E9-9278-68D0E5697425","grant_number":"281511","call_identifier":"FP7"},{"name":"Interneuro plasticity during spatial learning","grant_number":"I 3713-B27","call_identifier":"FWF","_id":"2654F984-B435-11E9-9278-68D0E5697425"}],"corr_author":"1","intvolume":"       113","issue":"9","publication":"Neuron","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","volume":113,"file_date_updated":"2025-08-05T12:43:44Z","year":"2025","PlanS_conform":"1","publication_status":"published","ec_funded":1,"oa":1,"has_accepted_license":"1","OA_type":"hybrid","abstract":[{"text":"Hippocampal reactivation of waking neuronal assemblies in sleep is a key initial step of systems consolidation. Nevertheless, it is unclear whether reactivated assemblies are static or whether they reorganize gradually over prolonged sleep. We tracked reactivated CA1 assembly patterns over ∼20 h of sleep/rest periods and related them to assemblies seen before or after in a spatial learning paradigm using rats. We found that reactivated assembly patterns were gradually transformed and started to resemble those seen in the subsequent recall session. Periods of rapid eye movement (REM) sleep and non-REM (NREM) had antagonistic roles: whereas NREM accelerated the assembly drift, REM countered it. Moreover, only a subset of rate-changing pyramidal cells contributed to the drift, whereas stable-firing-rate cells maintained unaltered reactivation patterns. Our data suggest that prolonged sleep promotes the spontaneous reorganization of spatial assemblies, which can contribute to daily cognitive map changes or encoding new learning situations.","lang":"eng"}],"oa_version":"Published Version","day":"07","isi":1,"pmid":1,"date_published":"2025-05-07T00:00:00Z","file":[{"file_name":"2025_Neuron_Bollmann.pdf","success":1,"date_updated":"2025-08-05T12:43:44Z","access_level":"open_access","relation":"main_file","checksum":"5e57852a45a78a751dd3a5e807bf015f","creator":"dernst","content_type":"application/pdf","file_id":"20133","file_size":27047730,"date_created":"2025-08-05T12:43:44Z"}],"month":"05","publication_identifier":{"issn":["0896-6273"],"eissn":["1097-4199"]},"citation":{"ista":"Bollmann L, Baracskay P, Stella F, Csicsvari JL. 2025. Sleep stages antagonistically modulate reactivation drift. Neuron. 113(9), 1446–1459.e6.","ama":"Bollmann L, Baracskay P, Stella F, Csicsvari JL. Sleep stages antagonistically modulate reactivation drift. <i>Neuron</i>. 2025;113(9):1446-1459.e6. doi:<a href=\"https://doi.org/10.1016/j.neuron.2025.02.025\">10.1016/j.neuron.2025.02.025</a>","short":"L. Bollmann, P. Baracskay, F. Stella, J.L. Csicsvari, Neuron 113 (2025) 1446–1459.e6.","apa":"Bollmann, L., Baracskay, P., Stella, F., &#38; Csicsvari, J. L. (2025). Sleep stages antagonistically modulate reactivation drift. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.neuron.2025.02.025\">https://doi.org/10.1016/j.neuron.2025.02.025</a>","chicago":"Bollmann, Lars, Peter Baracskay, Federico Stella, and Jozsef L Csicsvari. “Sleep Stages Antagonistically Modulate Reactivation Drift.” <i>Neuron</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.neuron.2025.02.025\">https://doi.org/10.1016/j.neuron.2025.02.025</a>.","ieee":"L. Bollmann, P. Baracskay, F. Stella, and J. L. Csicsvari, “Sleep stages antagonistically modulate reactivation drift,” <i>Neuron</i>, vol. 113, no. 9. Elsevier, p. 1446–1459.e6, 2025.","mla":"Bollmann, Lars, et al. “Sleep Stages Antagonistically Modulate Reactivation Drift.” <i>Neuron</i>, vol. 113, no. 9, Elsevier, 2025, p. 1446–1459.e6, doi:<a href=\"https://doi.org/10.1016/j.neuron.2025.02.025\">10.1016/j.neuron.2025.02.025</a>."},"type":"journal_article","doi":"10.1016/j.neuron.2025.02.025","page":"1446-1459.e6","external_id":{"isi":["001510440400001"],"pmid":["40132588"]},"title":"Sleep stages antagonistically modulate reactivation drift","OA_place":"publisher","quality_controlled":"1","status":"public","acknowledgement":"We thank Andrea Cumpelik, Lisa Genzel, and Freya Ólafsdóttir for comments on an earlier version of the manuscript. This work was supported by the European Research Council (281511) and Austrian Science Fund (FWF I3713).","date_updated":"2026-04-28T13:39:22Z","ddc":["570"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"article_type":"original"},{"department":[{"_id":"EdHa"}],"author":[{"first_name":"Marianne S.","full_name":"Andersen, Marianne S.","last_name":"Andersen"},{"first_name":"Svetlana","last_name":"Ulyanchenko","full_name":"Ulyanchenko, Svetlana"},{"full_name":"Schweiger, Pawel J.","last_name":"Schweiger","first_name":"Pawel J."},{"id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","orcid":"0000-0001-6005-1561","last_name":"Hannezo","full_name":"Hannezo, Edouard B"},{"first_name":"Benjamin D.","full_name":"Simons, Benjamin D.","last_name":"Simons"},{"last_name":"Jensen","full_name":"Jensen, Kim B.","first_name":"Kim B."}],"article_processing_charge":"No","scopus_import":"1","date_created":"2025-04-06T22:01:32Z","publisher":"Elsevier","language":[{"iso":"eng"}],"_id":"19507","publication_status":"published","oa":1,"OA_type":"hybrid","has_accepted_license":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":145,"file_date_updated":"2025-12-29T14:13:01Z","year":"2025","issue":"9","publication":"Journal of Investigative Dermatology","corr_author":"1","intvolume":"       145","doi":"10.1016/j.jid.2025.01.034","type":"journal_article","month":"09","publication_identifier":{"eissn":["1523-1747"],"issn":["0022-202X"]},"citation":{"ama":"Andersen MS, Ulyanchenko S, Schweiger PJ, Hannezo EB, Simons BD, Jensen KB. Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. <i>Journal of Investigative Dermatology</i>. 2025;145(9):2191-2202.e5. doi:<a href=\"https://doi.org/10.1016/j.jid.2025.01.034\">10.1016/j.jid.2025.01.034</a>","ista":"Andersen MS, Ulyanchenko S, Schweiger PJ, Hannezo EB, Simons BD, Jensen KB. 2025. Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. Journal of Investigative Dermatology. 145(9), 2191–2202.e5.","short":"M.S. Andersen, S. Ulyanchenko, P.J. Schweiger, E.B. Hannezo, B.D. Simons, K.B. Jensen, Journal of Investigative Dermatology 145 (2025) 2191–2202.e5.","apa":"Andersen, M. S., Ulyanchenko, S., Schweiger, P. J., Hannezo, E. B., Simons, B. D., &#38; Jensen, K. B. (2025). Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance. <i>Journal of Investigative Dermatology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jid.2025.01.034\">https://doi.org/10.1016/j.jid.2025.01.034</a>","chicago":"Andersen, Marianne S., Svetlana Ulyanchenko, Pawel J. Schweiger, Edouard B Hannezo, Benjamin D. Simons, and Kim B. Jensen. “Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance.” <i>Journal of Investigative Dermatology</i>. Elsevier, 2025. <a href=\"https://doi.org/10.1016/j.jid.2025.01.034\">https://doi.org/10.1016/j.jid.2025.01.034</a>.","ieee":"M. S. Andersen, S. Ulyanchenko, P. J. Schweiger, E. B. Hannezo, B. D. Simons, and K. B. Jensen, “Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance,” <i>Journal of Investigative Dermatology</i>, vol. 145, no. 9. Elsevier, p. 2191–2202.e5, 2025.","mla":"Andersen, Marianne S., et al. “Spatiotemporal Switches in Progenitor Cell Fate Govern Upper Hair Follicle Growth and Maintenance.” <i>Journal of Investigative Dermatology</i>, vol. 145, no. 9, Elsevier, 2025, p. 2191–2202.e5, doi:<a href=\"https://doi.org/10.1016/j.jid.2025.01.034\">10.1016/j.jid.2025.01.034</a>."},"isi":1,"date_published":"2025-09-01T00:00:00Z","pmid":1,"file":[{"date_created":"2025-12-29T14:13:01Z","file_size":7301679,"content_type":"application/pdf","file_id":"20874","relation":"main_file","access_level":"open_access","creator":"dernst","checksum":"a2b313de3cacb53f20f2b91c42612ad9","success":1,"file_name":"2025_JourInvestigativeDerma_Andersen.pdf","date_updated":"2025-12-29T14:13:01Z"}],"oa_version":"Published Version","abstract":[{"text":"The epidermis provides a protective barrier against hostile environments. However, our knowledge of how this barrier forms during development and is subsequently maintained remains incomplete. The infundibulum is a cylindrical epidermal tissue compartment that serves as an outlet for hair follicles protruding from the skin and the excretion of the sebaceous glands that are essential for proper skin function. In this study, we applied quantitative fate mapping to address how infundibulum are maintained during adulthood. We demonstrate that progenitors build and maintain tissues through stochastic cell fate choices. Long-term analysis identified a preferential transient contribution from cells initially located at the bottom of the structure to the maintenance of the tissue, with bursts of local progenitor expansion associated with the phases of hair growth. Beyond providing compartment-wide insights into progenitor cell dynamics in infundibulum, these findings demonstrate how spatiotemporal regulation controls transient progenitor dominance.","lang":"eng"}],"day":"01","ddc":["570"],"tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"article_type":"original","acknowledgement":"We thank the members of the Jensen Laboratory for experimental and technical advice, the imaging facilities at reNEW, and animal caretakers for expert assistance. This work was supported by the Lundbeck Foundation (R105-A9755 to KBJ) and the Leo Pharma Foundation (LF-OC-20-000169). The Novo Nordisk Foundation Center for Stem Cell Medicine was supported by a Novo Nordisk Foundation grant (NNF21CC0073729). B.D.S. was supported by the Wellcome Trust (219478/Z/19/Z) and a Royal Society EP Abraham Research Professorship (RP/R1/180165 and RP\\R\\231004). Figure elements were adapted from Bio-Render. KBJ is the lead contact and guarantor of this study.","date_updated":"2025-12-29T14:13:43Z","OA_place":"publisher","quality_controlled":"1","status":"public","page":"2191-2202.e5","external_id":{"pmid":["40010488"],"isi":["001604396400001"]},"title":"Spatiotemporal switches in progenitor cell fate govern upper hair follicle growth and maintenance"}]
