[{"citation":{"ista":"Bhargava M, Schreck C, Freire M, Hugron PA, Lefebvre S, Sellán S, Bickel B. 2025. Mesh simplification for unfolding. Computer Graphics Forum. 44(1), e15269.","apa":"Bhargava, M., Schreck, C., Freire, M., Hugron, P. A., Lefebvre, S., Sellán, S., &#38; Bickel, B. (2025). Mesh simplification for unfolding. <i>Computer Graphics Forum</i>. Wiley. <a href=\"https://doi.org/10.1111/cgf.15269\">https://doi.org/10.1111/cgf.15269</a>","short":"M. Bhargava, C. Schreck, M. Freire, P.A. Hugron, S. Lefebvre, S. Sellán, B. Bickel, Computer Graphics Forum 44 (2025).","ama":"Bhargava M, Schreck C, Freire M, et al. Mesh simplification for unfolding. <i>Computer Graphics Forum</i>. 2025;44(1). doi:<a href=\"https://doi.org/10.1111/cgf.15269\">10.1111/cgf.15269</a>","mla":"Bhargava, Manas, et al. “Mesh Simplification for Unfolding.” <i>Computer Graphics Forum</i>, vol. 44, no. 1, e15269, Wiley, 2025, doi:<a href=\"https://doi.org/10.1111/cgf.15269\">10.1111/cgf.15269</a>.","chicago":"Bhargava, Manas, Camille Schreck, M. Freire, P. A. Hugron, S. Lefebvre, S. Sellán, and Bernd Bickel. “Mesh Simplification for Unfolding.” <i>Computer Graphics Forum</i>. Wiley, 2025. <a href=\"https://doi.org/10.1111/cgf.15269\">https://doi.org/10.1111/cgf.15269</a>.","ieee":"M. Bhargava <i>et al.</i>, “Mesh simplification for unfolding,” <i>Computer Graphics Forum</i>, vol. 44, no. 1. Wiley, 2025."},"department":[{"_id":"GradSch"},{"_id":"BeBi"}],"type":"journal_article","oa":1,"doi":"10.1111/cgf.15269","acknowledgement":"Researchers from INRIA received support from the DORNELL Inria Challenge. Silvia Sellán acknowledges support from NSERC Vanier Doctoral Scholarship and an MIT SoE Postdoctoral Fellowship for Engineering Excellence.","publication_identifier":{"issn":["0167-7055"],"eissn":["1467-8659"]},"day":"01","_id":"18565","publication":"Computer Graphics Forum","file_date_updated":"2025-04-16T09:06:45Z","issue":"1","date_published":"2025-02-01T00:00:00Z","publisher":"Wiley","arxiv":1,"date_updated":"2026-05-04T12:41:52Z","month":"02","isi":1,"scopus_import":"1","year":"2025","abstract":[{"lang":"eng","text":"We present a computational approach for unfolding 3D shapes isometrically into the plane as a single patch without overlapping triangles. This is a hard, sometimes impossible, problem, which existing methods are forced to soften by allowing for map distortions or multiple patches. Instead, we propose a geometric relaxation of the problem: We modify the input shape until it admits an overlap‐free unfolding. We achieve this by locally displacing vertices and collapsing edges, guided by the unfolding process. We validate our algorithm quantitatively and qualitatively on a large dataset of complex shapes and show its proficiency by fabricating real shapes from paper."}],"file":[{"file_id":"18567","date_created":"2024-11-19T09:23:20Z","relation":"main_file","access_level":"open_access","creator":"mbhargav","file_name":"Mesh_Simplification_For_Unfolding_cgf_submission_supplemental_video.mp4","checksum":"34acdd9bfbe43f00eb6c7656afef3ac6","content_type":"video/mp4","success":1,"date_updated":"2024-11-19T09:23:20Z","file_size":36999751},{"content_type":"application/pdf","file_name":"2025_CompGraphicsForum_Bhargava.pdf","checksum":"efb06b01bae37f470954601bc004374d","file_size":5188265,"success":1,"date_updated":"2025-04-16T09:06:45Z","file_id":"19576","access_level":"open_access","creator":"dernst","date_created":"2025-04-16T09:06:45Z","relation":"main_file"}],"oa_version":"Published Version","article_processing_charge":"Yes (via OA deal)","publication_status":"published","OA_place":"publisher","language":[{"iso":"eng"}],"author":[{"id":"FF8FA64C-AA6A-11E9-99AD-50D4E5697425","last_name":"Bhargava","orcid":"0009-0007-6138-6890","first_name":"Manas","full_name":"Bhargava, Manas"},{"last_name":"Schreck","first_name":"Camille","full_name":"Schreck, Camille","id":"2B14B676-F248-11E8-B48F-1D18A9856A87"},{"first_name":"M.","full_name":"Freire, M.","last_name":"Freire"},{"full_name":"Hugron, P. A.","first_name":"P. A.","last_name":"Hugron"},{"last_name":"Lefebvre","full_name":"Lefebvre, S.","first_name":"S."},{"last_name":"Sellán","first_name":"S.","full_name":"Sellán, S."},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","first_name":"Bernd","full_name":"Bickel, Bernd","orcid":"0000-0001-6511-9385","last_name":"Bickel"}],"external_id":{"arxiv":["2408.06944"],"isi":["001357046100001"]},"status":"public","intvolume":"        44","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"quality_controlled":"1","title":"Mesh simplification for unfolding","OA_type":"hybrid","has_accepted_license":"1","volume":44,"related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"20276"}]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e15269","keyword":["fabrication","single patch unfolding","mesh simplification"],"date_created":"2024-11-19T09:14:32Z","ddc":["006"],"corr_author":"1","article_type":"original"},{"publication":"arXiv","day":"31","_id":"20286","doi":"10.48550/arXiv.2508.05410","acknowledgement":"The authors express gratitude to Magali Lorion for assisting in the initial fabrication of LCEs,\r\nPengbin Tang for providing the code for simulating discrete elastic rods, the Imaging and\r\nOptics Facility at ISTA for assisting with the spectrometry measurements, and the MIBA\r\nmachine shop at ISTA for their support in manufacturing various devices.\r\nFunding: This project was supported by the European Research Council (ERC) under\r\nthe European Union’s Horizon 2020 research and innovation program (Grant Agreement No.\r\n715767 -– MATERIALIZABLE).","type":"preprint","citation":{"ista":"Bhargava M, Hiraki T, Strugaru I-M, Zhang Y, Piovarci M, Daraio C, Iwai D, Bickel B. Computational design and fabrication of modular robots with untethered control. arXiv, <a href=\"https://doi.org/10.48550/arXiv.2508.05410\">10.48550/arXiv.2508.05410</a>.","apa":"Bhargava, M., Hiraki, T., Strugaru, I.-M., Zhang, Y., Piovarci, M., Daraio, C., … Bickel, B. (n.d.). Computational design and fabrication of modular robots with untethered control. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2508.05410\">https://doi.org/10.48550/arXiv.2508.05410</a>","short":"M. Bhargava, T. Hiraki, I.-M. Strugaru, Y. Zhang, M. Piovarci, C. Daraio, D. Iwai, B. Bickel, ArXiv (n.d.).","mla":"Bhargava, Manas, et al. “Computational Design and Fabrication of Modular Robots with Untethered Control.” <i>ArXiv</i>, doi:<a href=\"https://doi.org/10.48550/arXiv.2508.05410\">10.48550/arXiv.2508.05410</a>.","ama":"Bhargava M, Hiraki T, Strugaru I-M, et al. Computational design and fabrication of modular robots with untethered control. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2508.05410\">10.48550/arXiv.2508.05410</a>","chicago":"Bhargava, Manas, Takefumi Hiraki, Irina-Malina Strugaru, Yuhan Zhang, Michael Piovarci, Chiara Daraio, Daisuke Iwai, and Bernd Bickel. “Computational Design and Fabrication of Modular Robots with Untethered Control.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2508.05410\">https://doi.org/10.48550/arXiv.2508.05410</a>.","ieee":"M. Bhargava <i>et al.</i>, “Computational design and fabrication of modular robots with untethered control,” <i>arXiv</i>. ."},"department":[{"_id":"BeBi"}],"oa":1,"project":[{"call_identifier":"H2020","grant_number":"715767","name":"MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and Modeling","_id":"24F9549A-B435-11E9-9278-68D0E5697425"}],"article_processing_charge":"No","publication_status":"draft","OA_place":"repository","oa_version":"Preprint","date_updated":"2026-05-04T12:41:52Z","arxiv":1,"month":"08","abstract":[{"text":"Natural organisms utilize distributed actuation through their musculoskeletal\r\nsystems to adapt their gait for traversing diverse terrains or to morph their\r\nbodies for varied tasks. A longstanding challenge in robotics is to emulate\r\nthis capability of natural organisms, which has motivated the development of\r\nnumerous soft robotic systems. However, such systems are generally optimized\r\nfor a single functionality, lack the ability to change form or function on\r\ndemand, or remain tethered to bulky control systems. To address these\r\nlimitations, we present a framework for designing and controlling robots that\r\nutilize distributed actuation. We propose a novel building block that\r\nintegrates 3D-printed bones with liquid crystal elastomer (LCE) muscles as\r\nlightweight actuators, enabling the modular assembly of musculoskeletal robots.\r\nWe developed LCE rods that contract in response to infrared radiation, thereby\r\nproviding localized, untethered control over the distributed skeletal network\r\nand producing global deformations of the robot. To fully capitalize on the\r\nextensive design space, we introduce two computational tools: one for\r\noptimizing the robot's skeletal graph to achieve multiple target deformations,\r\nand another for co-optimizing skeletal designs and control gaits to realize\r\ndesired locomotion. We validate our framework by constructing several robots\r\nthat demonstrate complex shape morphing, diverse control schemes, and\r\nenvironmental adaptability. Our system integrates advances in modular material\r\nbuilding, untethered and distributed control, and computational design to\r\nintroduce a new generation of robots that brings us closer to the capabilities\r\nof living organisms.","lang":"eng"}],"year":"2025","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2508.05410","open_access":"1"}],"date_published":"2025-08-31T00:00:00Z","title":"Computational design and fabrication of modular robots with untethered control","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"status":"public","language":[{"iso":"eng"}],"external_id":{"arxiv":["2508.05410"]},"author":[{"orcid":"0009-0007-6138-6890","last_name":"Bhargava","first_name":"Manas","full_name":"Bhargava, Manas","id":"FF8FA64C-AA6A-11E9-99AD-50D4E5697425"},{"last_name":"Hiraki","full_name":"Hiraki, Takefumi","first_name":"Takefumi"},{"id":"2afc607f-f128-11eb-9611-8f2a0dfcf074","first_name":"Irina-Malina","full_name":"Strugaru, Irina-Malina","last_name":"Strugaru"},{"full_name":"Zhang, Yuhan","first_name":"Yuhan","last_name":"Zhang"},{"first_name":"Michael","full_name":"Piovarci, Michael","last_name":"Piovarci","orcid":"0000-0002-5062-4474","id":"62E473F4-5C99-11EA-A40E-AF823DDC885E"},{"last_name":"Daraio","full_name":"Daraio, Chiara","first_name":"Chiara"},{"full_name":"Iwai, Daisuke","first_name":"Daisuke","last_name":"Iwai"},{"first_name":"Bernd","full_name":"Bickel, Bernd","last_name":"Bickel","orcid":"0000-0001-6511-9385","id":"49876194-F248-11E8-B48F-1D18A9856A87"}],"date_created":"2025-09-04T09:14:11Z","corr_author":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","ec_funded":1,"related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"20276"}]}},{"publisher":"IEEE","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2404.04183","open_access":"1"}],"date_published":"2025-07-30T00:00:00Z","month":"07","arxiv":1,"date_updated":"2026-05-05T11:52:57Z","year":"2025","abstract":[{"text":"Widely deployed consensus protocols in the cloud are often leader-based and optimized for low latency under synchronous network conditions. However, cloud networks can experience disruptions such as network partitions, high-loss links, and configuration errors. These disruptions interfere with the operation of leader-based protocols, as their view change mechanisms interrupt the normal case replication and cause the system to stall. We propose RACS, a novel randomized consensus protocol that ensures robustness against adversarial network conditions. RACS achieves optimal one-round trip latency under synchronous network conditions while remaining resilient to adversarial network conditions. RACS follows a simple design inspired by Raft, the most widely used consensus protocol in the cloud, and therefore enables seamless integration with the existing cloud software stack. Experiments with a prototype running on Amazon EC2 show that RACS achieves 28k cmd/sec throughput, ninefold higher than Raft under adversarial cloud network conditions. Under synchronous network conditions, RACS matches the performance of Multi-Paxos and Raft, achieving a throughput of 200k cmd/sec with a median latency of 300ms, confirming that RACS introduces no unnecessary overhead. Finally, SADL-RACS, a throughput-optimized version of RACS, achieves a throughput of 500k cmd/sec, delivering 150 percent higher throughput than Raft.","lang":"eng"}],"scopus_import":"1","oa_version":"Preprint","article_processing_charge":"No","publication_status":"published","OA_place":"repository","citation":{"ieee":"P. Tennage, A. Desjardins, and E. Kokoris Kogias, “RACS-SADL: Robust and understandable randomized consensus in the cloud,” in <i>2025 IEEE 18th International Conference on Cloud Computing</i>, Helsinki, Finland, 2025.","chicago":"Tennage, Pasindu, Antoine Desjardins, and Eleftherios Kokoris Kogias. “RACS-SADL: Robust and Understandable Randomized Consensus in the Cloud.” In <i>2025 IEEE 18th International Conference on Cloud Computing</i>. IEEE, 2025. <a href=\"https://doi.org/10.1109/cloud67622.2025.00044\">https://doi.org/10.1109/cloud67622.2025.00044</a>.","ama":"Tennage P, Desjardins A, Kokoris Kogias E. RACS-SADL: Robust and understandable randomized consensus in the cloud. In: <i>2025 IEEE 18th International Conference on Cloud Computing</i>. IEEE; 2025. doi:<a href=\"https://doi.org/10.1109/cloud67622.2025.00044\">10.1109/cloud67622.2025.00044</a>","mla":"Tennage, Pasindu, et al. “RACS-SADL: Robust and Understandable Randomized Consensus in the Cloud.” <i>2025 IEEE 18th International Conference on Cloud Computing</i>, IEEE, 2025, doi:<a href=\"https://doi.org/10.1109/cloud67622.2025.00044\">10.1109/cloud67622.2025.00044</a>.","short":"P. Tennage, A. Desjardins, E. Kokoris Kogias, in:, 2025 IEEE 18th International Conference on Cloud Computing, IEEE, 2025.","apa":"Tennage, P., Desjardins, A., &#38; Kokoris Kogias, E. (2025). RACS-SADL: Robust and understandable randomized consensus in the cloud. In <i>2025 IEEE 18th International Conference on Cloud Computing</i>. Helsinki, Finland: IEEE. <a href=\"https://doi.org/10.1109/cloud67622.2025.00044\">https://doi.org/10.1109/cloud67622.2025.00044</a>","ista":"Tennage P, Desjardins A, Kokoris Kogias E. 2025. RACS-SADL: Robust and understandable randomized consensus in the cloud. 2025 IEEE 18th International Conference on Cloud Computing. CLOUD: Conference on Cloud Computing."},"type":"conference","department":[{"_id":"ElKo"}],"oa":1,"publication_identifier":{"eisbn":["9798331555573"]},"doi":"10.1109/cloud67622.2025.00044","_id":"21243","day":"30","publication":"2025 IEEE 18th International Conference on Cloud Computing","OA_type":"green","conference":{"location":"Helsinki, Finland","end_date":"2025-07-12","name":"CLOUD: Conference on Cloud Computing","start_date":"2025-07-07"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2026-02-16T15:21:27Z","corr_author":"1","author":[{"full_name":"Tennage, Pasindu","first_name":"Pasindu","last_name":"Tennage"},{"id":"06d0c166-aec1-11ee-a7c0-b96e840a602b","first_name":"Antoine","full_name":"Desjardins, Antoine","last_name":"Desjardins"},{"id":"f5983044-d7ef-11ea-ac6d-fd1430a26d30","full_name":"Kokoris Kogias, Eleftherios","first_name":"Eleftherios","last_name":"Kokoris Kogias","orcid":"0000-0002-8827-3382"}],"external_id":{"arxiv":["2404.04183"]},"language":[{"iso":"eng"}],"status":"public","title":"RACS-SADL: Robust and understandable randomized consensus in the cloud","quality_controlled":"1"},{"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"DOAJ_listed":"1","title":"Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids","quality_controlled":"1","author":[{"last_name":"Hübschmann","first_name":"Verena","full_name":"Hübschmann, Verena","id":"32B7C918-F248-11E8-B48F-1D18A9856A87"},{"id":"4B51CE74-F248-11E8-B48F-1D18A9856A87","first_name":"Medina","full_name":"Korkut, Medina","last_name":"Korkut","orcid":"0000-0003-4309-2251"},{"first_name":"Alessandro","full_name":"Venturino, Alessandro","orcid":"0000-0003-2356-9403","last_name":"Venturino","id":"41CB84B2-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Maya-Arteaga","first_name":"Juan Pablo","full_name":"Maya-Arteaga, Juan Pablo","id":"c815d433-1f5d-11f0-a875-dad18b1e5924"},{"id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","first_name":"Sandra","full_name":"Siegert, Sandra","orcid":"0000-0001-8635-0877","last_name":"Siegert"}],"external_id":{"isi":["001459311800002"],"pmid":["40181459"]},"APC_amount":"3948 EUR","language":[{"iso":"eng"}],"status":"public","intvolume":"        22","pmid":1,"PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"98","ddc":["570"],"date_created":"2025-04-20T22:01:28Z","article_type":"original","corr_author":"1","OA_type":"gold","has_accepted_license":"1","related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/pink-skies/"}],"record":[{"id":"20074","status":"public","relation":"dissertation_contains"}]},"volume":22,"_id":"19593","day":"03","publication":"Journal of Neuroinflammation","issue":"1","acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"file_date_updated":"2025-04-22T09:46:27Z","type":"journal_article","department":[{"_id":"SaSi"}],"citation":{"chicago":"Schmied, Verena, Medina Korkut, Alessandro Venturino, Juan Pablo Maya-Arteaga, and Sandra Siegert. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” <i>Journal of Neuroinflammation</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1186/s12974-025-03366-x\">https://doi.org/10.1186/s12974-025-03366-x</a>.","ieee":"V. Schmied, M. Korkut, A. Venturino, J. P. Maya-Arteaga, and S. Siegert, “Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids,” <i>Journal of Neuroinflammation</i>, vol. 22, no. 1. Springer Nature, 2025.","ista":"Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. 2025. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. Journal of Neuroinflammation. 22(1), 98.","apa":"Schmied, V., Korkut, M., Venturino, A., Maya-Arteaga, J. P., &#38; Siegert, S. (2025). Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. <i>Journal of Neuroinflammation</i>. Springer Nature. <a href=\"https://doi.org/10.1186/s12974-025-03366-x\">https://doi.org/10.1186/s12974-025-03366-x</a>","ama":"Schmied V, Korkut M, Venturino A, Maya-Arteaga JP, Siegert S. Microglia determine an immune-challenged environment and facilitate ibuprofen action in human retinal organoids. <i>Journal of Neuroinflammation</i>. 2025;22(1). doi:<a href=\"https://doi.org/10.1186/s12974-025-03366-x\">10.1186/s12974-025-03366-x</a>","mla":"Schmied, Verena, et al. “Microglia Determine an Immune-Challenged Environment and Facilitate Ibuprofen Action in Human Retinal Organoids.” <i>Journal of Neuroinflammation</i>, vol. 22, no. 1, 98, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1186/s12974-025-03366-x\">10.1186/s12974-025-03366-x</a>.","short":"V. Schmied, M. Korkut, A. Venturino, J.P. Maya-Arteaga, S. Siegert, Journal of Neuroinflammation 22 (2025)."},"oa":1,"acknowledgement":"We thank the scientific service units at ISTA, specifically the Lab Support Facility (LSF), the Molecular Biology Services/Virus Services Team, specifically Flavia Gama Gomes Leite and Mark Andrew Smyth, for the virus production, and the Imaging and Optics Facility (IOF). We thank all members of the Siegert group and Marco Benevento for their constant feedback on the project and comments on the manuscript. A special thanks to Rouven Schulz for input on statistical analysis and sharing R-scripts, Gloria Colombo for the introduction to cell sorting, Negar Vehdani and Florianne Schoot Uiterkamp for their support in cell culture. This research was supported by the Gesellschaft für Forschungsförderung Niederösterreich (grant No. Sc19-017 to V.H.).","publication_identifier":{"eissn":["1742-2094"]},"doi":"10.1186/s12974-025-03366-x","file":[{"file_name":"2025_JourNeuroinflammation_Schmied.pdf","checksum":"dcc355c21ab713e45fda5c61b5fa5299","content_type":"application/pdf","date_updated":"2025-04-22T09:46:27Z","success":1,"file_size":4482167,"file_id":"19607","date_created":"2025-04-22T09:46:27Z","relation":"main_file","access_level":"open_access","creator":"dernst"}],"oa_version":"Published Version","project":[{"name":"How human microglia shape developing neurons during health and inflammation","_id":"9B99D380-BA93-11EA-9121-9846C619BF3A","grant_number":"SC19-017"},{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"article_processing_charge":"Yes","publication_status":"published","OA_place":"publisher","publisher":"Springer Nature","date_published":"2025-04-03T00:00:00Z","isi":1,"month":"04","date_updated":"2026-05-06T12:49:37Z","year":"2025","abstract":[{"text":"Prenatal immune challenges pose significant risks to human embryonic brain and eye development. However, our knowledge about the safe usage of anti-inflammatory drugs during pregnancy is still limited. While human induced pluripotent stem cells (hIPSC)-derived brain organoid models have started to explore functional consequences upon viral stimulation, these models commonly lack microglia, which are susceptible to and promote inflammation. Furthermore, microglia are actively involved in neuronal development. Here, we generate hIPSC-derived microglia precursor cells and assemble them into retinal organoids. Once the outer plexiform layer forms, these hIPSC-derived microglia (iMG) fully integrate into the retinal organoids. Since the ganglion cell survival declines by this time in 3D-retinal organoids, we adapted the model into 2D and identify that the improved ganglion cell number significantly decreases only with iMG presence. In parallel, we applied the immunostimulant POLY(I:C) to mimic a fetal viral infection. While POLY(I:C) exposure alters the iMG phenotype, it does not hinder their interaction with ganglion cells. Furthermore, iMG significantly enhance the supernatant’s inflammatory secretome and increase retinal cell proliferation. Simultaneous exposure with the non-steroidal anti-inflammatory drug (NSAID) ibuprofen dampens POLY(I:C)-mediated changes of the iMG phenotype and ameliorates cell proliferation. Remarkably, while POLY(I:C) disrupts neuronal calcium dynamics independent of iMG, ibuprofen rescues this effect only if iMG are present. Mechanistically, ibuprofen targets the enzymes cyclooxygenase 1 and 2 (COX1/PTGS1 and COX2/PTGS2) simultaneously, from which iMG mainly express COX1. Selective COX1 blockage fails to restore the calcium peak amplitude upon POLY(I:C) stimulation, suggesting ibuprofen’s beneficial effect depends on the presence and interplay of COX1 and COX2. These findings underscore the importance of microglia in the context of prenatal immune challenges and provide insight into the mechanisms by which ibuprofen exerts its protective effects during embryonic development.","lang":"eng"}],"scopus_import":"1"},{"oa_version":"Published Version","file":[{"file_size":43566093,"date_updated":"2025-07-30T08:47:53Z","content_type":"application/x-zip-compressed","checksum":"d09f9984002353ad7442358394919bf3","file_name":"PhD_Thesis_Schmied.zip","creator":"vhuebsch","access_level":"closed","relation":"source_file","date_created":"2025-07-30T08:47:53Z","file_id":"20086"},{"content_type":"application/pdf","checksum":"4833690d7283c587f518ba98eeb2c946","file_name":"PhD_Thesis_Schmied.pdf","file_size":13120922,"date_updated":"2025-07-30T09:29:09Z","file_id":"20087","creator":"vhuebsch","access_level":"open_access","relation":"main_file","date_created":"2025-07-30T08:47:46Z"}],"project":[{"grant_number":"SC19-017","_id":"9B99D380-BA93-11EA-9121-9846C619BF3A","name":"How human microglia shape developing neurons during health and inflammation"}],"article_processing_charge":"No","publication_status":"published","OA_place":"publisher","date_published":"2025-07-24T00:00:00Z","publisher":"Institute of Science and Technology Austria","date_updated":"2026-05-06T12:49:36Z","month":"07","alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"Prenatal immune challenges pose significant risks to human embryonic brain and eye development. However, we still lack knowledge about the safe usage of anti-inflammatory drugs during pregnancy. Human induced pluripotent stem cell (hIPSC)-derived brain organoid models provide a unique opportunity to investigate neuronal development and have started to explore functional consequences upon viral infection. However, brain organoids usually lack microglia, the brain-resident immune cells. They are present in the early human embryonic brain and actively participate in neuronal circuit development. At the same time, microglia are known for their immune-sensing properties and will influence viral-mediated effects. In my thesis, I was interested to study the multifunctional role of human microglia during retinal development. \r\nIn chapter 1, I characterize the innate occurrence of IBA1+-microglia-like cells within the retinal organoid differentiation (Bartalska et al., 2022). Therefore, we differentiate hIPSC using an unguided retinal organoid differentiation protocol and observe the presence of IBA1+-microglia-like cells alongside retinal cups between week 3 and 4 in 2.5D culture. However, instead of infiltrating the neuroectodermal sides, they enrich within non-pigmented, 3D-cystic compartments that develop in low numbers parallel to 3D-retinal organoids. To enrich for IBA1+-microglia precursors (preMG), we guided the differentiation with a low-dosed BMP4 application, which prevents retinal cup development and enhances microglia and 3D-cysts formation. We characterize the differentiated preMG for their microglia-like identity and validated their functionality. In parallel, mass spectrometry identifies the 3D-cysts to express mesenchymal and epithelial markers. We confirm that comparable 3D-cysts are also the preferential environment for IBA1+-microglia-like cells within the unguided retinal organoid differentiation. \r\nIn chapter 2, I investigate how microglia influence retinal development and whether they contribute to viral-mediated consequences (Schmied et al., 2025). Here, we assemble preMG, which we have characterized in chapter 1, into 3D-retinal organoids. Once the outer plexiform layer forms, microglia-like cells (iMG) populate them and interact with retinal cell types. However, at this developmental stage, the ganglion cell number decreases in 3D-retinal organoids. Thus, we adapted the model into 2D which promotes their survival. Integrated iMG engulf ganglion cells and control their cell number. In parallel, we apply the immunostimulant POLY(I:C) to mimic a fetal viral infection. Although POLY(I:C) stimulation affects iMG phenotype, it does not influence their interaction with ganglion cells. Furthermore, iMG presence significantly contributes to the supernatant’s inflammatory secretome and increases retinal cell proliferation. Simultaneous exposure to the non-steroidal anti-inflammatory drug (NSAID) ibuprofen dampens POLY(I:C)-mediated consequences of the iMG phenotype and ameliorates cell proliferation. Remarkably, while POLY(I:C) disrupts neuronal calcium dynamics independent of iMG presence, ibuprofen rescues this effect only in the presence of iMG. Mechanistically, ibuprofen blocks the enzymes cyclooxygenase 1 and 2 (COX1/ PTGS1 and COX2/ PTGS2) simultaneously, from which iMG predominantly express COX1. Selective inhibition of COX1 does not restore the calcium peak amplitude upon POLY(I:C) stimulation, indicating ibuprofen’s effect depends on the presence and interplay of both, COX1 and COX2. \r\nIn summary, we characterized the 3D-retinal organoid model for the occurrence of IBA1+-microglia like cells. As the innately developing IBA1+-cells enrich in mesenchymal over retinal structures, we optimized a protocol to differentiate IBA1+-microglia precursors. By combining these two models we generate microglia-assembled retinal organoids. Our results underscore the importance of microglia during neurodevelopment, in the context of prenatal immune challenges and provide insight into the mechanisms by which ibuprofen exerts its protective effects during embryonic development."}],"year":"2025","_id":"20074","day":"24","file_date_updated":"2025-07-30T09:29:09Z","department":[{"_id":"GradSch"},{"_id":"SaSi"}],"citation":{"ieee":"V. Schmied, “ Human microglia impact neuronal development in retinal organoids,” Institute of Science and Technology Austria, 2025.","chicago":"Schmied, Verena. “ Human Microglia Impact Neuronal Development in Retinal Organoids.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20074\">https://doi.org/10.15479/AT-ISTA-20074</a>.","mla":"Schmied, Verena. <i> Human Microglia Impact Neuronal Development in Retinal Organoids</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20074\">10.15479/AT-ISTA-20074</a>.","ama":"Schmied V.  Human microglia impact neuronal development in retinal organoids. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20074\">10.15479/AT-ISTA-20074</a>","short":"V. Schmied,  Human Microglia Impact Neuronal Development in Retinal Organoids, Institute of Science and Technology Austria, 2025.","ista":"Schmied V. 2025.  Human microglia impact neuronal development in retinal organoids. Institute of Science and Technology Austria.","apa":"Schmied, V. (2025). <i> Human microglia impact neuronal development in retinal organoids</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20074\">https://doi.org/10.15479/AT-ISTA-20074</a>"},"type":"dissertation","oa":1,"doi":"10.15479/AT-ISTA-20074","degree_awarded":"PhD","publication_identifier":{"isbn":["978-3-99078-060-2"],"issn":["2663-337X"]},"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2025-07-24T12:37:22Z","ddc":["570"],"corr_author":"1","has_accepted_license":"1","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"11478"},{"id":"19593","relation":"part_of_dissertation","status":"public"}]},"page":"151","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":" Human microglia impact neuronal development in retinal organoids","language":[{"iso":"eng"}],"author":[{"id":"32B7C918-F248-11E8-B48F-1D18A9856A87","full_name":"Hübschmann, Verena","first_name":"Verena","last_name":"Hübschmann"}],"status":"public","supervisor":[{"last_name":"Siegert","orcid":"0000-0001-8635-0877","full_name":"Siegert, Sandra","first_name":"Sandra","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87"}]},{"doi":"10.1103/PhysRevX.15.011057","publication_identifier":{"eissn":["2160-3308"]},"acknowledgement":"We thank Helen Barron, Vezha Boboeva, Adam Packer, João Sacramento, Andrew Saxe, Misha Tsodyks, and Friedemann Zenke for helpful comments at various stages of this work, and Rubem Erichsen, Jr. for carefully reading the manuscript and valuable comments. This work was\r\nsupported by a Sir Henry Dale Fellowship by the Wellcome Trust and the Royal Society [No. WT100000 (W. F. P., E. J. A., and T. P. V.)], a Wellcome Trust Senior Research Fellowship [No. 214316/Z/18/Z (E. J. A. and T. P. V.)], and a Research Project Grant by the Leverhulme Trust\r\n[No. RPG-2016-446 (E. J. A.)]. ","type":"journal_article","citation":{"chicago":"Podlaski, William F., Everton J. Agnes, and Tim P Vogels. “High Capacity and Dynamic Accessibility in Associative Memory Networks with Context-Dependent Neuronal and Synaptic Gating.” <i>Physical Review X</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">https://doi.org/10.1103/PhysRevX.15.011057</a>.","ieee":"W. F. Podlaski, E. J. Agnes, and T. P. Vogels, “High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating,” <i>Physical Review X</i>, vol. 15. American Physical Society, 2025.","ista":"Podlaski WF, Agnes EJ, Vogels TP. 2025. High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. Physical Review X. 15, 011057.","apa":"Podlaski, W. F., Agnes, E. J., &#38; Vogels, T. P. (2025). High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. <i>Physical Review X</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">https://doi.org/10.1103/PhysRevX.15.011057</a>","short":"W.F. Podlaski, E.J. Agnes, T.P. Vogels, Physical Review X 15 (2025).","mla":"Podlaski, William F., et al. “High Capacity and Dynamic Accessibility in Associative Memory Networks with Context-Dependent Neuronal and Synaptic Gating.” <i>Physical Review X</i>, vol. 15, 011057, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">10.1103/PhysRevX.15.011057</a>.","ama":"Podlaski WF, Agnes EJ, Vogels TP. High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating. <i>Physical Review X</i>. 2025;15. doi:<a href=\"https://doi.org/10.1103/PhysRevX.15.011057\">10.1103/PhysRevX.15.011057</a>"},"department":[{"_id":"TiVo"}],"oa":1,"publication":"Physical Review X","file_date_updated":"2025-03-20T12:47:17Z","locked":"1","day":"13","_id":"8125","date_updated":"2026-05-06T12:44:27Z","isi":1,"month":"03","year":"2025","scopus_import":"1","abstract":[{"lang":"eng","text":"Biological memory is known to be flexible—memory formation and recall depend on factors such as the behavioral context of the organism. However, this property is often ignored in associative memory models, leaving it unclear how memories can be organized and recalled when subject to contextual control. Because of the lack of a rigorous analytical framework, it is also unknown how contextual control affects memory stability, storage capacity, and information content. Here, we bring the dynamic nature of memory to the fore by introducing a novel model of associative memory, which we refer to as the context-modular memory network. In our model, stored memory patterns are associated to one of several background network states, or contexts. Memories are accessible when their corresponding context is active, and are otherwise inaccessible. Context modulates the effective network connectivity by imposing a specific\r\nconfiguration of neuronal and synaptic gating—gated neurons (synapses) have their activity (weights) momentarily silenced, thereby reducing interference from memories belonging to other contexts. Memory patterns are randomly and independently chosen, while neuronal and synaptic gates may be selected randomly or optimized through a process of contextual synaptic refinement. Through analytic and numerical results, we show that context-modular memory networks can exhibit both improved memory capacity and differential control of memory stability with random gating (especially for neuronal gating). For contextual synaptic refinement, we devise a method in which synapses are gated off for a given context if they destabilize the memory patterns in that context, drastically improving memory capacity and enabling even more precise control over memory stability. Notably, synaptic refinement allows for patterns to be\r\naccessible in multiple contexts, stabilizing memory patterns even for weight matrices that alone do not contain any information about the memory patterns, such as Gaussian random matrices. Overall, our model integrates recent ideas about context-dependent memory organization with classic associative memory models and proposes a rigorous theory which can act as a framework for future work. Furthermore, our work carries important implications for the understanding of biological memory storage and recall in the brain, such as highlighting an intriguing trade-off between memory capacity and accessibility."}],"date_published":"2025-03-13T00:00:00Z","publisher":"American Physical Society","project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"},{"grant_number":"214316/Z/18/Z","_id":"c084a126-5a5b-11eb-8a69-d75314a70a87","name":"What’s in a memory? Spatiotemporal dynamics in strongly coupled recurrent neuronal networks."}],"article_processing_charge":"Yes","OA_place":"publisher","publication_status":"published","oa_version":"Published Version","file":[{"file_size":1373704,"success":1,"date_updated":"2025-03-20T12:47:17Z","content_type":"application/pdf","file_name":"2025_PhysReviewX_Podlaski.pdf","checksum":"1f27ee469ab51a3e1ce1e2df0022e81d","access_level":"open_access","creator":"dernst","date_created":"2025-03-20T12:47:17Z","relation":"main_file","file_id":"19432"}],"status":"public","intvolume":"        15","language":[{"iso":"eng"}],"author":[{"last_name":"Podlaski","orcid":"0000-0001-6619-7502","first_name":"William F.","full_name":"Podlaski, William F."},{"orcid":"0000-0001-7184-7311","last_name":"Agnes","full_name":"Agnes, Everton J.","first_name":"Everton J."},{"first_name":"Tim P","full_name":"Vogels, Tim P","last_name":"Vogels","orcid":"0000-0003-3295-6181","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425"}],"APC_amount":"4910,08 EUR","external_id":{"isi":["001451378900002"]},"quality_controlled":"1","title":"High capacity and dynamic accessibility in associative memory networks with context-dependent neuronal and synaptic gating","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"volume":15,"related_material":{"link":[{"url":"https://github.com/wpodlaski/contextual-memory-nets","relation":"software"}]},"OA_type":"gold","has_accepted_license":"1","date_created":"2020-07-16T12:24:28Z","ddc":["530"],"corr_author":"1","article_type":"original","article_number":"011057","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"status":"public","intvolume":"       122","language":[{"iso":"eng"}],"APC_amount":"3261,23 EUR","author":[{"first_name":"Mindy Liu","full_name":"Perkins, Mindy Liu","last_name":"Perkins"},{"last_name":"Crocker","first_name":"Justin","full_name":"Crocker, Justin"},{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455","last_name":"Tkačik","first_name":"Gašper","full_name":"Tkačik, Gašper"}],"external_id":{"pmid":["39793086"],"isi":["001392765300001"]},"quality_controlled":"1","title":"Chromatin enables precise and scalable gene regulation with factors of limited specificity","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"volume":122,"related_material":{"link":[{"relation":"software","url":"https://github.com/officerredshirt/network_crosstalk"}]},"OA_type":"hybrid","has_accepted_license":"1","date_created":"2025-01-19T23:01:51Z","ddc":["570"],"corr_author":"1","article_type":"original","pmid":1,"article_number":"e2411887121","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1073/pnas.2411887121","publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"acknowledgement":"M.L.P. was supported by the European Molecular Biology Laboratory (EMBL) Interdisciplinary Postdoc Programme (EIPOD4 fellowships), cofunded by Marie SkÅ‚odowska-Curie Actions (Grant Agreement No. 847543). J.C. and M.L.P. were supported by EMBL Core Funding and Theory@EMBL. This work is supported by European Research Council Grant DynaTrans (101118866) to G.T. We would like to thank the members of the J.C. and G.T. groups, especially Natalia Misunou, Michal Hledík, and Réka Borbély, for helpful feedback and discussion. We also thank EMBL IT Services for the use of high performance computing resources.","citation":{"chicago":"Perkins, Mindy Liu, Justin Crocker, and Gašper Tkačik. “Chromatin Enables Precise and Scalable Gene Regulation with Factors of Limited Specificity.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2411887121\">https://doi.org/10.1073/pnas.2411887121</a>.","ieee":"M. L. Perkins, J. Crocker, and G. Tkačik, “Chromatin enables precise and scalable gene regulation with factors of limited specificity,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 1. National Academy of Sciences, 2025.","apa":"Perkins, M. L., Crocker, J., &#38; Tkačik, G. (2025). Chromatin enables precise and scalable gene regulation with factors of limited specificity. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2411887121\">https://doi.org/10.1073/pnas.2411887121</a>","ista":"Perkins ML, Crocker J, Tkačik G. 2025. Chromatin enables precise and scalable gene regulation with factors of limited specificity. Proceedings of the National Academy of Sciences. 122(1), e2411887121.","short":"M.L. Perkins, J. Crocker, G. Tkačik, Proceedings of the National Academy of Sciences 122 (2025).","ama":"Perkins ML, Crocker J, Tkačik G. Chromatin enables precise and scalable gene regulation with factors of limited specificity. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(1). doi:<a href=\"https://doi.org/10.1073/pnas.2411887121\">10.1073/pnas.2411887121</a>","mla":"Perkins, Mindy Liu, et al. “Chromatin Enables Precise and Scalable Gene Regulation with Factors of Limited Specificity.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 1, e2411887121, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2411887121\">10.1073/pnas.2411887121</a>."},"department":[{"_id":"GaTk"}],"type":"journal_article","oa":1,"publication":"Proceedings of the National Academy of Sciences","file_date_updated":"2025-01-20T09:38:32Z","issue":"1","_id":"18850","day":"07","date_updated":"2026-05-06T12:43:59Z","month":"01","isi":1,"scopus_import":"1","year":"2025","abstract":[{"text":"Biophysical constraints limit the specificity with which transcription factors (TFs) can target regulatory DNA. While individual nontarget binding events may be low affinity, the sheer number of such interactions could present a challenge for gene regulation by degrading its precision or possibly leading to an erroneous induction state. Chromatin can prevent nontarget binding by rendering DNA physically inaccessible to TFs, at the cost of energy-consuming remodeling orchestrated by pioneer factors (PFs). Under what conditions and by how much can chromatin reduce regulatory errors on a global scale? We use a theoretical approach to compare two scenarios for gene regulation: one that relies on TF binding to free DNA alone and one that uses a combination of TFs and chromatin-regulating PFs to achieve desired gene expression patterns. We find, first, that chromatin effectively silences groups of genes that should be simultaneously OFF, thereby allowing more accurate graded control of expression for the remaining ON genes. Second, chromatin buffers the deleterious consequences of nontarget binding as the number of OFF genes grows, permitting a substantial expansion in regulatory complexity. Third, chromatin-based regulation productively co-opts nontarget TF binding for ON genes in order to establish a “leaky” baseline expression level, which targeted activator or repressor binding subsequently up- or down-modulates. Thus, on a global scale, using chromatin simultaneously alleviates pressure for high specificity of regulatory interactions and enables an increase in genome size with minimal impact on global expression error.","lang":"eng"}],"date_published":"2025-01-07T00:00:00Z","publisher":"National Academy of Sciences","article_processing_charge":"No","project":[{"_id":"7bfe6a29-9f16-11ee-852c-c0da5e2045d9","name":"Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos","grant_number":"101118866"}],"publication_status":"published","OA_place":"publisher","file":[{"file_name":"2025_PNAS_Perkins.pdf","checksum":"86a8d25a6e282aeb4128f1d0b86ff911","content_type":"application/pdf","success":1,"date_updated":"2025-01-20T09:38:32Z","file_size":30943709,"file_id":"18859","date_created":"2025-01-20T09:38:32Z","relation":"main_file","access_level":"open_access","creator":"dernst"}],"oa_version":"Published Version"},{"article_type":"original","corr_author":"1","ddc":["570"],"date_created":"2025-05-04T22:02:31Z","PlanS_conform":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e1012910","pmid":1,"related_material":{"link":[{"relation":"software","url":"https://github.com/VogelsLab/SpikES"}]},"volume":21,"ec_funded":1,"has_accepted_license":"1","OA_type":"gold","title":"Balancing complexity, performance and plausibility to meta learn plasticity rules in recurrent spiking networks","quality_controlled":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"DOAJ_listed":"1","intvolume":"        21","status":"public","author":[{"last_name":"Confavreux","first_name":"Basile J","full_name":"Confavreux, Basile J","id":"C7610134-B532-11EA-BD9F-F5753DDC885E"},{"last_name":"Agnes","first_name":"Everton J.","full_name":"Agnes, Everton J."},{"last_name":"Zenke","full_name":"Zenke, Friedemann","first_name":"Friedemann"},{"first_name":"Henning","full_name":"Sprekeler, Henning","last_name":"Sprekeler"},{"orcid":"0000-0003-3295-6181","last_name":"Vogels","full_name":"Vogels, Tim P","first_name":"Tim P","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425"}],"APC_amount":"3237,62 EUR","external_id":{"isi":["001474257000002"],"pmid":["40273284 "]},"language":[{"iso":"eng"}],"OA_place":"publisher","publication_status":"published","article_processing_charge":"Yes","project":[{"grant_number":"819603","call_identifier":"H2020","_id":"0aacfa84-070f-11eb-9043-d7eb2c709234","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning."},{"grant_number":"214316/Z/18/Z","name":"What’s in a memory? Spatiotemporal dynamics in strongly coupled recurrent neuronal networks.","_id":"c084a126-5a5b-11eb-8a69-d75314a70a87"}],"file":[{"file_name":"2025_PLoSCompBio_Confavreux.pdf","checksum":"6437a1aab52813ab7e310e3b4fb36e3b","content_type":"application/pdf","date_updated":"2025-05-05T11:17:49Z","success":1,"file_size":9771636,"file_id":"19654","date_created":"2025-05-05T11:17:49Z","relation":"main_file","access_level":"open_access","creator":"dernst"}],"oa_version":"Published Version","year":"2025","scopus_import":"1","abstract":[{"text":"Synaptic plasticity is a key player in the brain’s life-long learning abilities. However, due to experimental limitations, the mechanistic link between synaptic plasticity rules and the network-level computations they enable remain opaque. Here we use evolutionary strategies (ES) to meta learn local co-active plasticity rules in large recurrent spiking networks with excitatory (E) and inhibitory (I) neurons, using parameterizations of increasing complexity. We discover rules that robustly stabilize network dynamics for all four synapse types acting in isolation (E-to-E, E-to-I, I-to-E and I-to-I). More complex functions such as familiarity detection can also be included in the search constraints. However, our meta learning strategy begins to fail for co-active rules of increasing complexity, as it is challenging to devise loss functions that effectively constrain network dynamics to plausible solutions a priori. Moreover, in line with previous work, we can find multiple degenerate solutions with identical network behaviour. As a local optimization strategy, ES provides one solution at a time and makes exploration of this degeneracy cumbersome. Regardless, we can glean the interdependecies of various plasticity parameters by considering the covariance matrix learned alongside the optimal rule with ES. Our work provides a proof of principle for the success of machine-learning-guided discovery of plasticity rules in large spiking networks, and points at the necessity of more elaborate search strategies going forward.","lang":"eng"}],"month":"04","isi":1,"date_updated":"2026-05-06T13:17:52Z","publisher":"Public Library of Science","date_published":"2025-04-24T00:00:00Z","issue":"4","file_date_updated":"2025-05-05T11:17:49Z","publication":"PLoS Computational Biology","day":"24","_id":"19640","acknowledgement":"We would like to thank Chaitanya Chintaluri, Nicoleta Condruz and Douglas Feitosa Tomé for insightful discussions. This project has received funding from the HORIZON EUROPE European Research Council (ERC) consolidator grant\r\n(SYNAPSEEK, awarded to TV), a Wellcome Trust Sir Henry Dale Research Fellowship (WT100000, awarded to TV), a Wellcome Trust Senior Research Fellowship (214316/Z/18/Z, awarded to TV), and a Sir Henry Wellcome\r\nFellowship (110124/Z/15/Z, awarded to FZ). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.","publication_identifier":{"issn":["1553-734X"],"eissn":["1553-7358"]},"doi":"10.1371/journal.pcbi.1012910","oa":1,"type":"journal_article","citation":{"ista":"Confavreux BJ, Agnes EJ, Zenke F, Sprekeler H, Vogels TP. 2025. Balancing complexity, performance and plausibility to meta learn plasticity rules in recurrent spiking networks. PLoS Computational Biology. 21(4), e1012910.","apa":"Confavreux, B. J., Agnes, E. J., Zenke, F., Sprekeler, H., &#38; Vogels, T. P. (2025). Balancing complexity, performance and plausibility to meta learn plasticity rules in recurrent spiking networks. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1012910\">https://doi.org/10.1371/journal.pcbi.1012910</a>","short":"B.J. Confavreux, E.J. Agnes, F. Zenke, H. Sprekeler, T.P. Vogels, PLoS Computational Biology 21 (2025).","ama":"Confavreux BJ, Agnes EJ, Zenke F, Sprekeler H, Vogels TP. Balancing complexity, performance and plausibility to meta learn plasticity rules in recurrent spiking networks. <i>PLoS Computational Biology</i>. 2025;21(4). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1012910\">10.1371/journal.pcbi.1012910</a>","mla":"Confavreux, Basile J., et al. “Balancing Complexity, Performance and Plausibility to Meta Learn Plasticity Rules in Recurrent Spiking Networks.” <i>PLoS Computational Biology</i>, vol. 21, no. 4, e1012910, Public Library of Science, 2025, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1012910\">10.1371/journal.pcbi.1012910</a>.","chicago":"Confavreux, Basile J, Everton J. Agnes, Friedemann Zenke, Henning Sprekeler, and Tim P Vogels. “Balancing Complexity, Performance and Plausibility to Meta Learn Plasticity Rules in Recurrent Spiking Networks.” <i>PLoS Computational Biology</i>. Public Library of Science, 2025. <a href=\"https://doi.org/10.1371/journal.pcbi.1012910\">https://doi.org/10.1371/journal.pcbi.1012910</a>.","ieee":"B. J. Confavreux, E. J. Agnes, F. Zenke, H. Sprekeler, and T. P. Vogels, “Balancing complexity, performance and plausibility to meta learn plasticity rules in recurrent spiking networks,” <i>PLoS Computational Biology</i>, vol. 21, no. 4. Public Library of Science, 2025."},"department":[{"_id":"TiVo"}]},{"acknowledgement":"We would like to thank Rebecca Morse for performing the recordings in one of the animals under the supervision of H.S.C.C., Jago Wallenschus for the technical support, especially with maze design, Wiktor Mlynarski for the advice and discussions and Andrea Cumpelik for suggestions during the writing. M.N. was supported by the Howard Hughes Medical Institute. H.S.C.C. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 665385.","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"doi":"10.1073/pnas.2417025122","type":"journal_article","department":[{"_id":"GaTk"},{"_id":"JoCs"}],"citation":{"apa":"Chiossi, H. S. C., Nardin, M., Tkačik, G., &#38; Csicsvari, J. L. (2025). Learning reshapes the hippocampal representation hierarchy. <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2417025122\">https://doi.org/10.1073/pnas.2417025122</a>","ista":"Chiossi HSC, Nardin M, Tkačik G, Csicsvari JL. 2025. Learning reshapes the hippocampal representation hierarchy. Proceedings of the National Academy of Sciences. 122(11), e2417025122.","ama":"Chiossi HSC, Nardin M, Tkačik G, Csicsvari JL. Learning reshapes the hippocampal representation hierarchy. <i>Proceedings of the National Academy of Sciences</i>. 2025;122(11). doi:<a href=\"https://doi.org/10.1073/pnas.2417025122\">10.1073/pnas.2417025122</a>","mla":"Chiossi, Heloisa S. C., et al. “Learning Reshapes the Hippocampal Representation Hierarchy.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 11, e2417025122, National Academy of Sciences, 2025, doi:<a href=\"https://doi.org/10.1073/pnas.2417025122\">10.1073/pnas.2417025122</a>.","short":"H.S.C. Chiossi, M. Nardin, G. Tkačik, J.L. Csicsvari, Proceedings of the National Academy of Sciences 122 (2025).","chicago":"Chiossi, Heloisa S. C., Michele Nardin, Gašper Tkačik, and Jozsef L Csicsvari. “Learning Reshapes the Hippocampal Representation Hierarchy.” <i>Proceedings of the National Academy of Sciences</i>. National Academy of Sciences, 2025. <a href=\"https://doi.org/10.1073/pnas.2417025122\">https://doi.org/10.1073/pnas.2417025122</a>.","ieee":"H. S. C. Chiossi, M. Nardin, G. Tkačik, and J. L. Csicsvari, “Learning reshapes the hippocampal representation hierarchy,” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 11. National Academy of Sciences, 2025."},"oa":1,"publication":"Proceedings of the National Academy of Sciences","issue":"11","file_date_updated":"2025-03-25T07:49:04Z","_id":"19453","day":"10","isi":1,"month":"03","date_updated":"2026-05-06T13:12:01Z","abstract":[{"text":"A key feature of biological and artificial neural networks is the progressive refinement of their neural representations with experience. In neuroscience, this fact has inspired several recent studies in sensory and motor systems. However, less is known about how higher associational cortical areas, such as the hippocampus, modify representations throughout the learning of complex tasks. Here, we focus on associative learning, a process that requires forming a connection between the representations of different variables for appropriate behavioral response. We trained rats in a space-context associative task and monitored hippocampal neural activity throughout the entire learning period, over several days. This allowed us to assess changes in the representations of context, movement direction, and position, as well as their relationship to behavior. We identified a hierarchical representational structure in the encoding of these three task variables that was preserved throughout learning. Nevertheless, we also observed changes at the lower levels of the hierarchy where context was encoded. These changes were local in neural activity space and restricted to physical positions where context identification was necessary for correct decision-making, supporting better context decoding and contextual code compression. Our results demonstrate that the hippocampal code not only accommodates hierarchical relationships between different variables but also enables efficient learning through minimal changes in neural activity space. Beyond the hippocampus, our work reveals a representation learning mechanism that might be implemented in other biological and artificial networks performing similar tasks.","lang":"eng"}],"scopus_import":"1","year":"2025","publisher":"National Academy of Sciences","date_published":"2025-03-10T00:00:00Z","article_processing_charge":"Yes (in subscription journal)","project":[{"name":"International IST Doctoral Program","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385","call_identifier":"H2020"}],"OA_place":"publisher","publication_status":"published","file":[{"file_id":"19454","access_level":"open_access","creator":"dernst","date_created":"2025-03-25T07:49:04Z","relation":"main_file","content_type":"application/pdf","file_name":"2025_PNAS_Chiossi.pdf","checksum":"1217207c254553154faa065964990988","file_size":1553502,"date_updated":"2025-03-25T07:49:04Z","success":1}],"oa_version":"Published Version","status":"public","intvolume":"       122","author":[{"last_name":"Chiossi","orcid":"0009-0004-2973-278X","full_name":"Chiossi, Heloisa","first_name":"Heloisa","id":"2BBA502C-F248-11E8-B48F-1D18A9856A87"},{"id":"30BD0376-F248-11E8-B48F-1D18A9856A87","last_name":"Nardin","orcid":"0000-0001-8849-6570","first_name":"Michele","full_name":"Nardin, Michele"},{"first_name":"Gašper","full_name":"Tkačik, Gašper","orcid":"0000-0002-6699-1455","last_name":"Tkačik","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87"},{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5193-4036","last_name":"Csicsvari","full_name":"Csicsvari, Jozsef L","first_name":"Jozsef L"}],"external_id":{"isi":["001459499500001"],"pmid":["40063792"]},"APC_amount":"3317,75 EUR","language":[{"iso":"eng"}],"title":"Learning reshapes the hippocampal representation hierarchy","quality_controlled":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"ec_funded":1,"related_material":{"link":[{"url":"https://github.com/hchiossi/hpc-hierarchy","relation":"software"}],"record":[{"id":"18991","relation":"research_data","status":"public"}]},"volume":122,"OA_type":"hybrid","has_accepted_license":"1","ddc":["570"],"date_created":"2025-03-25T07:38:35Z","article_type":"original","corr_author":"1","pmid":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"e2417025122"},{"oa_version":"Published Version","file":[{"file_name":"2025_njpQuantumMaterials_Kumar.pdf","checksum":"08b1a94b362bb65482887e50020810e5","content_type":"application/pdf","date_updated":"2025-04-10T06:12:49Z","success":1,"file_size":592092,"file_id":"19536","date_created":"2025-04-10T06:12:49Z","relation":"main_file","access_level":"open_access","creator":"dernst"}],"project":[{"_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854","name":"IST Austria Open Access Fund"}],"article_processing_charge":"Yes","OA_place":"publisher","publication_status":"published","publisher":"Springer Nature","date_published":"2025-04-04T00:00:00Z","month":"04","isi":1,"date_updated":"2026-05-06T13:06:08Z","abstract":[{"text":"In standard quantum electrodynamics (QED), the so-called non-minimal (Pauli) coupling is suppressed for elementary particles and has no physical implications. Here, we show that the Pauli term naturally appears in a known family of Dirac materials—the lead-halide perovskites, suggesting a novel playground for the study of analog QED effects. We outline measurable manifestations of the Pauli term in the phenomena pertaining to (i) relativistic corrections to bound states (ii) the Klein paradox, and (iii) spin effects in scattering. In particular, we demonstrate that (a) the binding energy of an electron in the vicinity of a positively charged defect is noticeably decreased due to the polarizability of lead ions and the appearance of a Darwin-like term, (b) strong spin-orbit coupling due to the Pauli term affects the exciton states, and (c) scattering of an electron off an energy barrier with broken mirror symmetry produces spin polarization in the outgoing current. Our study adds to the understanding of quantum phenomena in lead-halide perovskites and paves the way for tabletop simulations of analog Dirac-Pauli equations.","lang":"eng"}],"scopus_import":"1","year":"2025","_id":"19531","day":"04","publication":"npj Quantum Materials","file_date_updated":"2025-04-10T06:12:49Z","department":[{"_id":"GradSch"},{"_id":"ZhAl"},{"_id":"MiLe"}],"citation":{"apa":"Shiva Kumar, A., Maslov, M., Lemeshko, M., Volosniev, A., &#38; Alpichshev, Z. (2025). Massive Dirac-Pauli physics in lead-halide perovskites. <i>Npj Quantum Materials</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41535-025-00754-7\">https://doi.org/10.1038/s41535-025-00754-7</a>","ista":"Shiva Kumar A, Maslov M, Lemeshko M, Volosniev A, Alpichshev Z. 2025. Massive Dirac-Pauli physics in lead-halide perovskites. npj Quantum Materials. 10, 37.","mla":"Shiva Kumar, Abhishek, et al. “Massive Dirac-Pauli Physics in Lead-Halide Perovskites.” <i>Npj Quantum Materials</i>, vol. 10, 37, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41535-025-00754-7\">10.1038/s41535-025-00754-7</a>.","ama":"Shiva Kumar A, Maslov M, Lemeshko M, Volosniev A, Alpichshev Z. Massive Dirac-Pauli physics in lead-halide perovskites. <i>npj Quantum Materials</i>. 2025;10. doi:<a href=\"https://doi.org/10.1038/s41535-025-00754-7\">10.1038/s41535-025-00754-7</a>","short":"A. Shiva Kumar, M. Maslov, M. Lemeshko, A. Volosniev, Z. Alpichshev, Npj Quantum Materials 10 (2025).","chicago":"Shiva Kumar, Abhishek, Mikhail Maslov, Mikhail Lemeshko, Artem Volosniev, and Zhanybek Alpichshev. “Massive Dirac-Pauli Physics in Lead-Halide Perovskites.” <i>Npj Quantum Materials</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41535-025-00754-7\">https://doi.org/10.1038/s41535-025-00754-7</a>.","ieee":"A. Shiva Kumar, M. Maslov, M. Lemeshko, A. Volosniev, and Z. Alpichshev, “Massive Dirac-Pauli physics in lead-halide perovskites,” <i>npj Quantum Materials</i>, vol. 10. Springer Nature, 2025."},"type":"journal_article","oa":1,"publication_identifier":{"eissn":["2397-4648"]},"doi":"10.1038/s41535-025-00754-7","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"37","ddc":["530"],"date_created":"2025-04-08T18:13:06Z","article_type":"original","corr_author":"1","OA_type":"gold","has_accepted_license":"1","related_material":{"link":[{"relation":"software","url":"https://git.ista.ac.at/mmaslov/dirac_pauli_LHP"}]},"volume":10,"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"DOAJ_listed":"1","title":"Massive Dirac-Pauli physics in lead-halide perovskites","quality_controlled":"1","author":[{"id":"5e9a6931-eb97-11eb-a6c2-e96f7058d77a","full_name":"Shiva Kumar, Abhishek","first_name":"Abhishek","last_name":"Shiva Kumar"},{"id":"2E65BB0E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4074-2570","last_name":"Maslov","full_name":"Maslov, Mikhail","first_name":"Mikhail"},{"last_name":"Lemeshko","orcid":"0000-0002-6990-7802","full_name":"Lemeshko, Mikhail","first_name":"Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"},{"id":"37D278BC-F248-11E8-B48F-1D18A9856A87","last_name":"Volosniev","orcid":"0000-0003-0393-5525","full_name":"Volosniev, Artem","first_name":"Artem"},{"id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","full_name":"Alpichshev, Zhanybek","first_name":"Zhanybek","last_name":"Alpichshev","orcid":"0000-0002-7183-5203"}],"APC_amount":"3054 EUR","external_id":{"isi":["001459830100002"]},"language":[{"iso":"eng"}],"status":"public","intvolume":"        10"},{"file_date_updated":"2025-02-03T08:27:59Z","publication":"Physical Review Research","day":"22","_id":"18986","publication_identifier":{"issn":["2643-1564"]},"acknowledgement":"J.B., F.C., and Y.X. were funded by the European Union (ERC, CHORAL, Project No. 101039794). Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. M.M. was supported by the 2019 Lopez-Loreta Prize. J.B. acknowledges discussions with TianQi Hou at the initial stage of the project, as well as with Antoine Bodin.","doi":"10.1103/PhysRevResearch.7.013081","oa":1,"citation":{"mla":"Barbier, Jean, et al. “Information Limits and Thouless-Anderson-Palmer Equations for Spiked Matrix Models with Structured Noise.” <i>Physical Review Research</i>, vol. 7, 013081, American Physical Society, 2025, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.7.013081\">10.1103/PhysRevResearch.7.013081</a>.","ama":"Barbier J, Camilli F, Xu Y, Mondelli M. Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise. <i>Physical Review Research</i>. 2025;7. doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.7.013081\">10.1103/PhysRevResearch.7.013081</a>","short":"J. Barbier, F. Camilli, Y. Xu, M. Mondelli, Physical Review Research 7 (2025).","apa":"Barbier, J., Camilli, F., Xu, Y., &#38; Mondelli, M. (2025). Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.7.013081\">https://doi.org/10.1103/PhysRevResearch.7.013081</a>","ista":"Barbier J, Camilli F, Xu Y, Mondelli M. 2025. Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise. Physical Review Research. 7, 013081.","ieee":"J. Barbier, F. Camilli, Y. Xu, and M. Mondelli, “Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise,” <i>Physical Review Research</i>, vol. 7. American Physical Society, 2025.","chicago":"Barbier, Jean, Francesco Camilli, Yizhou Xu, and Marco Mondelli. “Information Limits and Thouless-Anderson-Palmer Equations for Spiked Matrix Models with Structured Noise.” <i>Physical Review Research</i>. American Physical Society, 2025. <a href=\"https://doi.org/10.1103/PhysRevResearch.7.013081\">https://doi.org/10.1103/PhysRevResearch.7.013081</a>."},"type":"journal_article","department":[{"_id":"MaMo"}],"OA_place":"publisher","publication_status":"published","article_processing_charge":"Yes","project":[{"_id":"059876FA-7A3F-11EA-A408-12923DDC885E","name":"Prix Lopez-Loretta 2019 - Marco Mondelli"}],"file":[{"file_size":702543,"success":1,"date_updated":"2025-02-03T08:27:59Z","content_type":"application/pdf","checksum":"52c5f72d80ffc928542469114fcdb62b","file_name":"2025_PhysReviewResearch_Barbier.pdf","creator":"dernst","access_level":"open_access","relation":"main_file","date_created":"2025-02-03T08:27:59Z","file_id":"18988"}],"oa_version":"Published Version","scopus_import":"1","abstract":[{"text":"We consider a prototypical problem of Bayesian inference for a structured spiked model: a low-rank signal is corrupted by additive noise. While both information-theoretic and algorithmic limits are well understood when the noise is a Gaussian Wigner matrix, the more realistic case of structured noise still remains challenging. To capture the structure while maintaining mathematical tractability, a line of work has focused on rotationally invariant noise. However, existing studies either provide suboptimal algorithms or are limited to a special class of noise ensembles. In this paper, using tools from statistical physics (replica method) and random matrix theory (generalized spherical integrals) we establish the characterization of the information-theoretic limits for a noise matrix drawn from a general trace ensemble. Remarkably, our analysis unveils the asymptotic equivalence between the rotationally invariant model and a surrogate Gaussian one. Finally, we show how to saturate the predicted statistical limits using an efficient algorithm inspired by the theory of adaptive Thouless-Anderson-Palmer (TAP) equations.","lang":"eng"}],"year":"2025","month":"01","date_updated":"2026-05-06T12:57:36Z","arxiv":1,"publisher":"American Physical Society","date_published":"2025-01-22T00:00:00Z","title":"Information limits and Thouless-Anderson-Palmer equations for spiked matrix models with structured noise","quality_controlled":"1","DOAJ_listed":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"intvolume":"         7","status":"public","APC_amount":"3272,21 EUR","external_id":{"arxiv":["2405.20993"]},"author":[{"last_name":"Barbier","first_name":"Jean","full_name":"Barbier, Jean"},{"first_name":"Francesco","full_name":"Camilli, Francesco","last_name":"Camilli"},{"full_name":"Xu, Yizhou","first_name":"Yizhou","last_name":"Xu"},{"id":"27EB676C-8706-11E9-9510-7717E6697425","full_name":"Mondelli, Marco","first_name":"Marco","orcid":"0000-0002-3242-7020","last_name":"Mondelli"}],"language":[{"iso":"eng"}],"article_type":"original","ddc":["530"],"date_created":"2025-02-02T23:01:54Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"013081","related_material":{"link":[{"url":"https://github.com/xu-yz19/spiked-matrix-models-with-structured-noise","relation":"software"}]},"volume":7,"has_accepted_license":"1","OA_type":"gold"},{"date_published":"2025-07-01T00:00:00Z","publisher":"World Scientific Publishing","year":"2025","abstract":[{"text":"A maximal realization of the two-dimensional Pauli operator, subject to Aharonov–Bohm magnetic field, is investigated. Contrary to the case of the Pauli operator with regular magnetic potentials, it is shown that both components of the Pauli operator are critical. Asymptotics of the weakly coupled eigenvalues, generated by electric (not necessarily self-adjoint) perturbations, are derived.","lang":"eng"}],"scopus_import":"1","arxiv":1,"date_updated":"2026-05-06T13:03:25Z","isi":1,"month":"07","oa_version":"Published Version","file":[{"checksum":"559d97ee2da28bf0bd2c6af507f3a914","file_name":"2025_ReviewsMathPhysics_Fialova.pdf","content_type":"application/pdf","success":1,"date_updated":"2025-12-30T08:23:12Z","file_size":484646,"file_id":"20893","relation":"main_file","date_created":"2025-12-30T08:23:12Z","creator":"dernst","access_level":"open_access"}],"publication_status":"published","OA_place":"publisher","project":[{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"}],"article_processing_charge":"Yes (in subscription journal)","oa":1,"department":[{"_id":"RoSe"}],"type":"journal_article","citation":{"ista":"Fialova M, Krejčiřík D. 2025. Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. Reviews in Mathematical Physics. 37(6), 2550011.","apa":"Fialova, M., &#38; Krejčiřík, D. (2025). Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. <i>Reviews in Mathematical Physics</i>. World Scientific Publishing. <a href=\"https://doi.org/10.1142/S0129055X25500114\">https://doi.org/10.1142/S0129055X25500114</a>","short":"M. Fialova, D. Krejčiřík, Reviews in Mathematical Physics 37 (2025).","ama":"Fialova M, Krejčiřík D. Virtual bound states of the Pauli operator with an Aharonov–Bohm potential. <i>Reviews in Mathematical Physics</i>. 2025;37(6). doi:<a href=\"https://doi.org/10.1142/S0129055X25500114\">10.1142/S0129055X25500114</a>","mla":"Fialova, Marie, and David Krejčiřík. “Virtual Bound States of the Pauli Operator with an Aharonov–Bohm Potential.” <i>Reviews in Mathematical Physics</i>, vol. 37, no. 6, 2550011, World Scientific Publishing, 2025, doi:<a href=\"https://doi.org/10.1142/S0129055X25500114\">10.1142/S0129055X25500114</a>.","chicago":"Fialova, Marie, and David Krejčiřík. “Virtual Bound States of the Pauli Operator with an Aharonov–Bohm Potential.” <i>Reviews in Mathematical Physics</i>. World Scientific Publishing, 2025. <a href=\"https://doi.org/10.1142/S0129055X25500114\">https://doi.org/10.1142/S0129055X25500114</a>.","ieee":"M. Fialova and D. Krejčiřík, “Virtual bound states of the Pauli operator with an Aharonov–Bohm potential,” <i>Reviews in Mathematical Physics</i>, vol. 37, no. 6. World Scientific Publishing, 2025."},"doi":"10.1142/S0129055X25500114","publication_identifier":{"eissn":["1793-6659"],"issn":["0129-055X"]},"acknowledgement":"Thanks belong to Johannes Ageskov and Matˇej Tuˇsek for helpful discussions on some technical details. M. F. would further like to acknowledge support for research on this paper from the European Unions Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101034413 as well as support by funding from Villum Fonden through the QMATH Centreof Excellence Grant No. 10059. D. K. was supported by the EXPRO Grant No.20-17749X of the Czech Science Foundation (GACR).","_id":"19705","day":"01","file_date_updated":"2025-12-30T08:23:12Z","issue":"6","publication":"Reviews in Mathematical Physics","has_accepted_license":"1","OA_type":"hybrid","volume":37,"ec_funded":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_number":"2550011","PlanS_conform":"1","article_type":"original","date_created":"2025-05-18T22:02:51Z","ddc":["530","510"],"language":[{"iso":"eng"}],"external_id":{"isi":["001481012500001"],"arxiv":["2501.17029"]},"author":[{"id":"e9c9844d-9e21-11ec-b482-f96fc09f7c4d","full_name":"Fialova, Marie","first_name":"Marie","last_name":"Fialova"},{"last_name":"Krejčiřík","first_name":"David","full_name":"Krejčiřík, David"}],"APC_amount":"2320,48 EUR","intvolume":"        37","status":"public","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"quality_controlled":"1","title":"Virtual bound states of the Pauli operator with an Aharonov–Bohm potential"},{"publisher":"Institute of Science and Technology Austria","date_published":"2025-02-04T00:00:00Z","month":"02","date_updated":"2026-05-06T13:12:00Z","year":"2025","abstract":[{"text":"Research data for the article \"Learning reshapes the hippocampal representation hierarchy\" from Chiossi et al. (PNAS, 2025). The data includes hippocampal CA1 unit activity and behaviour tracking of 5 Long Evans rats during the learning of an associative memory task. Detailed information can be found in the 'readme.txt' file.","lang":"eng"}],"file":[{"content_type":"application/zip","checksum":"04d761ed42e8879abffde04a560409ce","file_name":"Chiossi_etal_2025_PNAS_data.zip","file_size":769383201,"success":1,"date_updated":"2025-02-04T10:16:52Z","file_id":"18992","creator":"hchiossi","access_level":"open_access","relation":"main_file","date_created":"2025-02-04T10:16:52Z"},{"relation":"main_file","date_created":"2025-02-04T10:18:33Z","creator":"hchiossi","access_level":"open_access","file_id":"18993","date_updated":"2025-02-04T10:18:33Z","success":1,"file_size":3215,"checksum":"50602931dcd33e4f009ed46af11335f3","file_name":"readme.txt","content_type":"text/plain"}],"oa_version":"Published Version","article_processing_charge":"No","OA_place":"repository","department":[{"_id":"GradSch"},{"_id":"JoCs"},{"_id":"GaTk"}],"type":"research_data","citation":{"apa":"Chiossi, H. S. C. (2025). Research data for the publication “Learning reshapes the hippocampal representation hierarchy.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:18991\">https://doi.org/10.15479/AT:ISTA:18991</a>","ista":"Chiossi HSC. 2025. Research data for the publication ‘Learning reshapes the hippocampal representation hierarchy’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:18991\">10.15479/AT:ISTA:18991</a>.","short":"H.S.C. Chiossi, (2025).","ama":"Chiossi HSC. Research data for the publication “Learning reshapes the hippocampal representation hierarchy.” 2025. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18991\">10.15479/AT:ISTA:18991</a>","mla":"Chiossi, Heloisa S. C. <i>Research Data for the Publication “Learning Reshapes the Hippocampal Representation Hierarchy.”</i> Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18991\">10.15479/AT:ISTA:18991</a>.","chicago":"Chiossi, Heloisa S. C. “Research Data for the Publication ‘Learning Reshapes the Hippocampal Representation Hierarchy.’” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT:ISTA:18991\">https://doi.org/10.15479/AT:ISTA:18991</a>.","ieee":"H. S. C. Chiossi, “Research data for the publication ‘Learning reshapes the hippocampal representation hierarchy.’” Institute of Science and Technology Austria, 2025."},"oa":1,"acknowledgement":"Thanks to Rebecca Morse for performing one of the experiments under H.S.C.C. supervision and Jago Wallenschus for technical support, especially with maze design.","doi":"10.15479/AT:ISTA:18991","_id":"18991","day":"04","file_date_updated":"2025-02-04T10:18:33Z","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"M-Shop"}],"OA_type":"gold","has_accepted_license":"1","related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"19453"}]},"contributor":[{"last_name":"Nardin","orcid":"0000-0001-8849-6570","first_name":"Michele","contributor_type":"researcher","id":"30BD0376-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Tkačik","orcid":"0000-0002-6699-1455","contributor_type":"supervisor","first_name":"Gašper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Csicsvari","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","contributor_type":"supervisor","id":"3FA14672-F248-11E8-B48F-1D18A9856A87"}],"keyword":["hippocampus","electrophysiology","behavior"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"date_created":"2025-02-04T10:36:18Z","corr_author":"1","author":[{"id":"2BBA502C-F248-11E8-B48F-1D18A9856A87","full_name":"Chiossi, Heloisa","first_name":"Heloisa","orcid":"0009-0004-2973-278X","last_name":"Chiossi"}],"status":"public","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"title":"Research data for the publication \"Learning reshapes the hippocampal representation hierarchy\""},{"oa_version":"None","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","conference":{"location":"Timisoara, Romania","start_date":"2025-09-22","end_date":"2025-09-25","name":"SYNASC: Symposium on Symbolic and Numeric Algorithms for Scientific Computing"},"publication_status":"published","corr_author":"1","article_processing_charge":"No","date_created":"2026-05-17T22:02:11Z","date_published":"2025-10-01T00:00:00Z","publisher":"IEEE","OA_type":"closed access","scopus_import":"1","year":"2025","abstract":[{"text":"Symbolic datatypes have proved to be central for automated reasoning about dynamical systems. In its basic form, a symbolic datatype for a class of dynamical systems supports the representation of state and transition sets, boolean operations and emptiness checks on such sets, and the transformation of a state set by a transition set. Successful examples of symbolic datatypes include BDDs and SAT for reasoning about finitestate systems, as well as polyhedra and SMT for reasoning about discrete dynamical systems over multidimensional realvalued state spaces. Most automated verification engines are based on such symbolic datatypes.","lang":"eng"}],"date_updated":"2026-05-18T08:34:15Z","month":"10","day":"01","_id":"21885","quality_controlled":"1","publication":"Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing","title":"Neural Certificates","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-2985-7724","last_name":"Henzinger","full_name":"Henzinger, Thomas A","first_name":"Thomas A","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"}],"department":[{"_id":"ToHe"}],"type":"conference","citation":{"short":"T.A. Henzinger, in:, Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing, IEEE, 2025.","ama":"Henzinger TA. Neural Certificates. In: <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. IEEE; 2025. doi:<a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">10.1109/SYNASC69064.2025.00008</a>","mla":"Henzinger, Thomas A. “Neural Certificates.” <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>, IEEE, 2025, doi:<a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">10.1109/SYNASC69064.2025.00008</a>.","apa":"Henzinger, T. A. (2025). Neural Certificates. In <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. Timisoara, Romania: IEEE. <a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">https://doi.org/10.1109/SYNASC69064.2025.00008</a>","ista":"Henzinger TA. 2025. Neural Certificates. Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing. SYNASC: Symposium on Symbolic and Numeric Algorithms for Scientific Computing.","ieee":"T. A. Henzinger, “Neural Certificates,” in <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>, Timisoara, Romania, 2025.","chicago":"Henzinger, Thomas A. “Neural Certificates.” In <i>Proceedings of the 27th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing</i>. IEEE, 2025. <a href=\"https://doi.org/10.1109/SYNASC69064.2025.00008\">https://doi.org/10.1109/SYNASC69064.2025.00008</a>."},"doi":"10.1109/SYNASC69064.2025.00008","publication_identifier":{"eissn":["2470-881X"],"eisbn":["9798331590116"]},"status":"public"},{"date_created":"2026-05-11T08:55:23Z","corr_author":"1","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"21854"}]},"OA_type":"green","title":"Position: It's time to act on the risk of efficient personalized text generation","status":"public","external_id":{"arxiv":["2502.06560"]},"author":[{"id":"f9a17499-f6e0-11ea-865d-fdf9a3f77117","last_name":"Iofinova","orcid":"0000-0002-7778-3221","first_name":"Eugenia B","full_name":"Iofinova, Eugenia B"},{"full_name":"Jovanovic, Andrej","first_name":"Andrej","last_name":"Jovanovic"},{"full_name":"Alistarh, Dan-Adrian","first_name":"Dan-Adrian","last_name":"Alistarh","orcid":"0000-0003-3650-940X","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"article_processing_charge":"No","project":[{"grant_number":"101158077","name":"FastML: Efficient and Cost-Effective Distributed Machine Learning","_id":"8e35c14b-16d5-11f0-9cad-a3fc35339161"},{"name":"Vienna Graduate School on Computational Optimization","_id":"9B9290DE-BA93-11EA-9121-9846C619BF3A","grant_number":"W1260-N35"}],"OA_place":"repository","publication_status":"draft","oa_version":"Preprint","month":"06","arxiv":1,"date_updated":"2026-05-19T11:20:27Z","abstract":[{"text":"The recent surge in high-quality open-source Generative AI text models (colloquially: LLMs), as well as efficient finetuning techniques, have opened the possibility of creating high-quality personalized models that generate text attuned to a specific individual’s needs and are capable of credibly imitating their writing style by refining an open-source model with that person’s own data. The technology to create such models is accessible to private individuals, and training and running such models can be done cheaply on consumer-grade hardware. While these advancements are a huge gain for usability and privacy, this position paper argues that the practical feasibility of impersonating specific individuals also introduces novel safety risks. For instance, this technology enables the creation of phishing emails\r\nor fraudulent social media accounts, based on small amounts of publicly available text, or by the individuals themselves to escape AI text detection. We further argue that these risks are complementary to—and distinct from—the much-discussed risks of other impersonation attacks such as image, voice, or video deepfakes, and are not adequately addressed by the larger research community, or the current generation of open- and closed-source models.","lang":"eng"}],"year":"2025","date_published":"2025-06-02T00:00:00Z","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2502.06560","open_access":"1"}],"publication":"arXiv","_id":"21858","day":"02","acknowledgement":"This research was supported by the Scientific Service Units (SSU) of IST Austria through resources\r\nprovided by Scientific Computing (SciComp). EI was supported in part by the FWF DK VGSCO,\r\ngrant agreement number W1260-N35. AJ was supported in part by ERC Proof-of-Concept Grant\r\nFastML, grant agreement 101158077.","doi":"10.48550/arXiv.2502.06560","type":"preprint","citation":{"ieee":"E. B. Iofinova, A. Jovanovic, and D.-A. Alistarh, “Position: It’s time to act on the risk of efficient personalized text generation,” <i>arXiv</i>. .","chicago":"Iofinova, Eugenia B, Andrej Jovanovic, and Dan-Adrian Alistarh. “Position: It’s Time to Act on the Risk of Efficient Personalized Text Generation.” <i>ArXiv</i>, n.d. <a href=\"https://doi.org/10.48550/arXiv.2502.06560\">https://doi.org/10.48550/arXiv.2502.06560</a>.","ama":"Iofinova EB, Jovanovic A, Alistarh D-A. Position: It’s time to act on the risk of efficient personalized text generation. <i>arXiv</i>. doi:<a href=\"https://doi.org/10.48550/arXiv.2502.06560\">10.48550/arXiv.2502.06560</a>","mla":"Iofinova, Eugenia B., et al. “Position: It’s Time to Act on the Risk of Efficient Personalized Text Generation.” <i>ArXiv</i>, doi:<a href=\"https://doi.org/10.48550/arXiv.2502.06560\">10.48550/arXiv.2502.06560</a>.","short":"E.B. Iofinova, A. Jovanovic, D.-A. Alistarh, ArXiv (n.d.).","apa":"Iofinova, E. B., Jovanovic, A., &#38; Alistarh, D.-A. (n.d.). Position: It’s time to act on the risk of efficient personalized text generation. <i>arXiv</i>. <a href=\"https://doi.org/10.48550/arXiv.2502.06560\">https://doi.org/10.48550/arXiv.2502.06560</a>","ista":"Iofinova EB, Jovanovic A, Alistarh D-A. Position: It’s time to act on the risk of efficient personalized text generation. arXiv, <a href=\"https://doi.org/10.48550/arXiv.2502.06560\">10.48550/arXiv.2502.06560</a>."},"department":[{"_id":"GradSch"},{"_id":"DaAl"}],"oa":1},{"ec_funded":1,"volume":16,"related_material":{"record":[{"relation":"earlier_version","status":"public","id":"18144"},{"status":"public","relation":"research_data","id":"18886"}]},"OA_type":"gold","has_accepted_license":"1","date_created":"2025-03-16T23:01:23Z","ddc":["530"],"corr_author":"1","article_type":"original","pmid":1,"article_number":"2103","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","status":"public","intvolume":"        16","language":[{"iso":"eng"}],"author":[{"id":"396A1950-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0003-9037-8831","last_name":"Janik","first_name":"Marian","full_name":"Janik, Marian"},{"id":"53f93ea2-803f-11ed-ab7e-b283135794ef","last_name":"Roux","full_name":"Roux, Kevin Etienne Robert","first_name":"Kevin Etienne Robert"},{"first_name":"Carla N","full_name":"Borja Espinosa, Carla N","last_name":"Borja Espinosa","id":"18777c01-896a-11ed-bdf8-e4851dc07d16"},{"id":"71616374-A8E9-11E9-A7CA-09ECE5697425","first_name":"Oliver","full_name":"Sagi, Oliver","last_name":"Sagi"},{"last_name":"Baghdadi","first_name":"Abdulhamid","full_name":"Baghdadi, Abdulhamid","id":"160D87FA-96B5-11E9-BF77-7626E6697425"},{"id":"38756BB2-F248-11E8-B48F-1D18A9856A87","first_name":"Thomas","full_name":"Adletzberger, Thomas","last_name":"Adletzberger"},{"last_name":"Calcaterra","full_name":"Calcaterra, Stefano","first_name":"Stefano"},{"full_name":"Botifoll, Marc","first_name":"Marc","last_name":"Botifoll"},{"full_name":"Garzón Manjón, Alba","first_name":"Alba","last_name":"Garzón Manjón"},{"last_name":"Arbiol","first_name":"Jordi","full_name":"Arbiol, Jordi"},{"first_name":"Daniel","full_name":"Chrastina, Daniel","last_name":"Chrastina"},{"first_name":"Giovanni","full_name":"Isella, Giovanni","last_name":"Isella"},{"full_name":"Pop, Ioan M.","first_name":"Ioan M.","last_name":"Pop"},{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","first_name":"Georgios","full_name":"Katsaros, Georgios","last_name":"Katsaros","orcid":"0000-0001-8342-202X"}],"APC_amount":"7068 EUR","external_id":{"isi":["001434774800001"],"arxiv":["2407.03079"],"pmid":["40025007"]},"quality_controlled":"1","title":"Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"DOAJ_listed":"1","date_updated":"2026-05-20T06:34:51Z","arxiv":1,"isi":1,"month":"03","scopus_import":"1","abstract":[{"lang":"eng","text":"High kinetic inductance superconductors are gaining increasing interest for the realisation of qubits, amplifiers and detectors. Moreover, thanks to their high impedance, quantum buses made of such materials enable large zero-point fluctuations of the voltage, boosting the coupling rates to spin and charge qubits. However, fully exploiting the potential of disordered or granular superconductors is challenging, as their inductance and, therefore, impedance at high values are difficult to control. Here, we report a reproducible fabrication of granular aluminium resonators by developing a wireless ohmmeter, which allows in situ measurements during film deposition and, therefore, control of the kinetic inductance of granular aluminium films. Reproducible fabrication of circuits with impedances (inductances) exceeding 13 kΩ (1 nH per square) is now possible. By integrating a 7.9 kΩ resonator with a germanium double quantum dot, we demonstrate strong charge-photon coupling with a rate of gc/2π = 566 ± 2 MHz. This broadly applicable method opens the path for novel qubits and high-fidelity, long-distance two-qubit gates."}],"year":"2025","date_published":"2025-03-01T00:00:00Z","publisher":"Springer Nature","article_processing_charge":"Yes","project":[{"grant_number":"101069515","_id":"34c0acea-11ca-11ed-8bc3-8775e10fd452","name":"Integrated Germanium Quantum Technology"},{"name":"Towards scalable hut wire quantum devices","_id":"237B3DA4-32DE-11EA-91FC-C7463DDC885E","call_identifier":"FWF","grant_number":"P32235"},{"grant_number":"I05060","name":"High impedance circuit quantum electrodynamics with hole spins","_id":"c0977eea-5a5b-11eb-8a69-a862db0cf4d1"},{"grant_number":"P36507","name":"Merging spin and superconducting qubits in planar Ge","_id":"bd8bd29e-d553-11ed-ba76-f0070d4b237a"},{"_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","name":"IST-BRIDGE: International postdoctoral program","call_identifier":"H2020","grant_number":"101034413"},{"name":"FWF Open Access Fund","_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","call_identifier":"FWF"}],"OA_place":"publisher","publication_status":"published","file":[{"date_updated":"2025-03-17T10:53:32Z","success":1,"file_size":6364878,"file_name":"2025_NatureComm_Janik.pdf","checksum":"a9383dd978ca2c50b7dded6c0bb2cd49","content_type":"application/pdf","date_created":"2025-03-17T10:53:32Z","relation":"main_file","access_level":"open_access","creator":"dernst","file_id":"19415"}],"oa_version":"Published Version","doi":"10.1038/s41467-025-57252-4","publication_identifier":{"eissn":["2041-1723"]},"acknowledgement":"We acknowledge Franco De Palma, Mahya Khorramshahi, Fabian Oppliger, Thomas Reisinger, Pasquale Scarlino and Xiao Xue for helpful discussions. We thank Simon Robson for proofreading the manuscript. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication facility. This research and related results were made possible with the support of the NOMIS Foundation and the HORIZON-RIA 101069515 project. This research was funded in whole or in part by the Austrian Science Fund (FWF) https://doi.org/10.55776/P32235, https://doi.org/10.55776/I5060 and https://doi.org/10.55776/P36507. For Open Access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. M.J. acknowledges funding from FellowQUTE 2024-01. K.R. acknowledges funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 101034413. I.M.P. acknowledges funding from the Deutsche Forschungsgemeinschaft (DFG - German Research Foundation) under project number 450396347 (GeHoldeQED). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. We acknowledge support from CSIC Interdisciplinary Thematic Platform (PTI+) on Quantum Technologies (PTI-QTEP+). This research work has been funded by the European Commission - NextGenerationEU (Regulation EU 2020/2094), through CSIC’s Quantum Technologies Platform (QTEP). ICN2 is supported by the Severo Ochoa programme from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD programme. AGM has received funding from Grant RYC2021-033479-I funded by MCIN/AEI/10.13039/501100011033 and by European Union NextGenerationEU/PRTR. M.B. acknowledges support from SUR Generalitat de Catalunya and the EU Social Fund; project ref. 2020 FI 00103. The authors acknowledge the use of instrumentation and the technical advice provided by the Joint Electron Microscopy Centre at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is a founding member of e-DREAM60.","citation":{"ieee":"M. Janik <i>et al.</i>, “Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors,” <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.","chicago":"Janik, Marian, Kevin Etienne Robert Roux, Carla N Borja Espinosa, Oliver Sagi, Abdulhamid Baghdadi, Thomas Adletzberger, Stefano Calcaterra, et al. “Strong Charge-Photon Coupling in Planar Germanium Enabled by Granular Aluminium Superinductors.” <i>Nature Communications</i>. Springer Nature, 2025. <a href=\"https://doi.org/10.1038/s41467-025-57252-4\">https://doi.org/10.1038/s41467-025-57252-4</a>.","short":"M. Janik, K.E.R. Roux, C.N. Borja Espinosa, O. Sagi, A. Baghdadi, T. Adletzberger, S. Calcaterra, M. Botifoll, A. Garzón Manjón, J. Arbiol, D. Chrastina, G. Isella, I.M. Pop, G. Katsaros, Nature Communications 16 (2025).","ama":"Janik M, Roux KER, Borja Espinosa CN, et al. Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors. <i>Nature Communications</i>. 2025;16. doi:<a href=\"https://doi.org/10.1038/s41467-025-57252-4\">10.1038/s41467-025-57252-4</a>","mla":"Janik, Marian, et al. “Strong Charge-Photon Coupling in Planar Germanium Enabled by Granular Aluminium Superinductors.” <i>Nature Communications</i>, vol. 16, 2103, Springer Nature, 2025, doi:<a href=\"https://doi.org/10.1038/s41467-025-57252-4\">10.1038/s41467-025-57252-4</a>.","ista":"Janik M, Roux KER, Borja Espinosa CN, Sagi O, Baghdadi A, Adletzberger T, Calcaterra S, Botifoll M, Garzón Manjón A, Arbiol J, Chrastina D, Isella G, Pop IM, Katsaros G. 2025. Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors. Nature Communications. 16, 2103.","apa":"Janik, M., Roux, K. E. R., Borja Espinosa, C. N., Sagi, O., Baghdadi, A., Adletzberger, T., … Katsaros, G. (2025). Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-025-57252-4\">https://doi.org/10.1038/s41467-025-57252-4</a>"},"department":[{"_id":"GeKa"},{"_id":"JoFi"},{"_id":"M-Shop"}],"type":"journal_article","oa":1,"publication":"Nature Communications","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"file_date_updated":"2025-03-17T10:53:32Z","_id":"19401","day":"01"},{"_id":"19566","day":"01","publication":"Investigative Ophthalmology & Visual Science","issue":"3","file_date_updated":"2025-04-15T13:49:10Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"PreCl"}],"type":"journal_article","department":[{"_id":"SaSi"}],"citation":{"chicago":"Miteva, Florianne E, Margaret E Maes, Mohammad Alamalhoda, Arsalan Firoozi, Gloria Colombo, and Sandra Siegert. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” <i>Investigative Ophthalmology &#38; Visual Science</i>. Association for Research in Vision and Ophthalmology, 2025. <a href=\"https://doi.org/10.1167/iovs.66.3.49\">https://doi.org/10.1167/iovs.66.3.49</a>.","ieee":"F. E. Miteva, M. E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, and S. Siegert, “Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye,” <i>Investigative Ophthalmology &#38; Visual Science</i>, vol. 66, no. 3. Association for Research in Vision and Ophthalmology, 2025.","apa":"Miteva, F. E., Maes, M. E., Alamalhoda, M., Firoozi, A., Colombo, G., &#38; Siegert, S. (2025). Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. <i>Investigative Ophthalmology &#38; Visual Science</i>. Association for Research in Vision and Ophthalmology. <a href=\"https://doi.org/10.1167/iovs.66.3.49\">https://doi.org/10.1167/iovs.66.3.49</a>","ista":"Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. 2025. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. Investigative Ophthalmology &#38; Visual Science. 66(3), 49.","short":"F.E. Miteva, M.E. Maes, M. Alamalhoda, A. Firoozi, G. Colombo, S. Siegert, Investigative Ophthalmology &#38; Visual Science 66 (2025).","mla":"Miteva, Florianne E., et al. “Optic Nerve Crush Does Not Induce Retinal Ganglion Cell Loss in the Contralateral Eye.” <i>Investigative Ophthalmology &#38; Visual Science</i>, vol. 66, no. 3, 49, Association for Research in Vision and Ophthalmology, 2025, doi:<a href=\"https://doi.org/10.1167/iovs.66.3.49\">10.1167/iovs.66.3.49</a>.","ama":"Miteva FE, Maes ME, Alamalhoda M, Firoozi A, Colombo G, Siegert S. Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye. <i>Investigative Ophthalmology &#38; Visual Science</i>. 2025;66(3). doi:<a href=\"https://doi.org/10.1167/iovs.66.3.49\">10.1167/iovs.66.3.49</a>"},"oa":1,"acknowledgement":"The authors thank the Scientific Service Units (SSU) of ISTA for the provided resources, specifically the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF), and the Pre-Clinical Facility (PCF) team, specifically Sonja Haslinger, Claudia Gold, and Michael Schunn, for mouse colony management and support. We thank all members of the Siegert group for constant feedback on the project and the manuscript. \r\nSupported in whole or in part by the Austrian Science Fund (FWF) [10.55776/P37131]. For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission. ","publication_identifier":{"issn":["1552-5783"]},"doi":"10.1167/iovs.66.3.49","file":[{"creator":"dernst","access_level":"open_access","relation":"main_file","date_created":"2025-04-15T13:49:10Z","file_id":"19567","file_size":2721477,"date_updated":"2025-04-15T13:49:10Z","success":1,"content_type":"application/pdf","checksum":"e8722ce5792f6c08fe1e191f7de6f147","file_name":"2025_IOVS_SchootUiterkamp.pdf"}],"oa_version":"Published Version","project":[{"grant_number":"P37131","_id":"7be82147-9f16-11ee-852c-f44682d73140","name":"Dissecting the morpho-functional relationship of microglia"},{"_id":"3AC91DDA-15DF-11EA-824D-93A3E7B544D1","name":"FWF Open Access Fund","call_identifier":"FWF"}],"article_processing_charge":"Yes","OA_place":"publisher","publication_status":"published","publisher":"Association for Research in Vision and Ophthalmology","date_published":"2025-03-01T00:00:00Z","month":"03","date_updated":"2026-05-20T06:37:12Z","abstract":[{"lang":"eng","text":"Purpose: Optic nerve crush (ONC) is a model for studying optic nerve trauma. Unilateral ONC induces massive retinal ganglion cell (RGC) degeneration in the affected eye, leading to vision loss within a month. A common assumption has been that the non-injured contralateral eye is unaffected due to the minimal retino-retinal projections of the RGCs at the chiasm. Yet, recently, microglia, the brain-resident macrophages, have shown a responsive phenotype in the contralateral eye after ONC. Whether RGC loss accompanies this phenotype is still controversial.\r\n\r\nMethods: Using the available RGCode algorithm and developing our own RGC-Quant deep-learning-based tool, we quantify RGC's total number and density across the entire retina after ONC.\r\n\r\nResults: We confirm a short-term microglia response in the contralateral eye after ONC, but this did not affect the microglia number. Furthermore, we cannot confirm the previously reported RGC loss between naïve and contralateral retinas 5 weeks after ONC induction across the commonly used Cx3cr1creERT2 and C57BL6/J mouse models. Neither sex nor the direct comparison of the RGC markers Brn3a and RBPMS, with Brn3a co-labeling, on average, 89% of the RBPMS+-cells, explained this discrepancy, suggesting that the early microglia-responsive phenotype does not have immediate consequences on the RGC number.\r\n\r\nConclusions: Our results corroborate that unilateral optic nerve injury elicits a microglial response in the uninjured contralateral eye but without RGC loss. Therefore, the contralateral eye should be treated separately and not as an ONC control."}],"scopus_import":"1","year":"2025","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"DOAJ_listed":"1","title":"Optic nerve crush does not induce retinal ganglion cell loss in the contralateral eye","quality_controlled":"1","APC_amount":"2236,02 EUR","external_id":{"pmid":["40126507"]},"author":[{"id":"3526230C-F248-11E8-B48F-1D18A9856A87","first_name":"Florianne E","full_name":"Schoot Uiterkamp, Florianne E","last_name":"Schoot Uiterkamp"},{"orcid":"0000-0001-9642-1085","last_name":"Maes","full_name":"Maes, Margaret E","first_name":"Margaret E","id":"3838F452-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Mohammad","full_name":"Alamalhoda, Mohammad","last_name":"Alamalhoda"},{"first_name":"Arsalan","full_name":"Firoozi, Arsalan","last_name":"Firoozi"},{"orcid":"0000-0001-9434-8902","last_name":"Colombo","full_name":"Colombo, Gloria","first_name":"Gloria","id":"3483CF6C-F248-11E8-B48F-1D18A9856A87"},{"id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8635-0877","last_name":"Siegert","full_name":"Siegert, Sandra","first_name":"Sandra"}],"language":[{"iso":"eng"}],"status":"public","intvolume":"        66","pmid":1,"article_number":"49","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","ddc":["570"],"date_created":"2025-04-15T13:40:35Z","article_type":"original","corr_author":"1","OA_type":"gold","has_accepted_license":"1","related_material":{"link":[{"url":"https://github.com/siegert-lab/RGC-Quant","relation":"software"}],"record":[{"id":"20467","status":"public","relation":"dissertation_contains"}]},"volume":66},{"day":"27","_id":"18886","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"NanoFab"}],"file_date_updated":"2025-01-27T11:27:35Z","oa":1,"type":"research_data","department":[{"_id":"GeKa"},{"_id":"GradSch"}],"citation":{"chicago":"Janik, Marian. “Research Data for Publication ‘Strong Charge-Photon Coupling in Planar Germanium Enabled by Granular Aluminium Superinductors.’” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT:ISTA:18886\">https://doi.org/10.15479/AT:ISTA:18886</a>.","ieee":"M. Janik, “Research data for publication ‘Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors.’” Institute of Science and Technology Austria, 2025.","apa":"Janik, M. (2025). Research data for publication “Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:18886\">https://doi.org/10.15479/AT:ISTA:18886</a>","ista":"Janik M. 2025. Research data for publication ‘Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:18886\">10.15479/AT:ISTA:18886</a>.","short":"M. Janik, (2025).","ama":"Janik M. Research data for publication “Strong charge-photon coupling in planar germanium enabled by granular aluminium superinductors.” 2025. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18886\">10.15479/AT:ISTA:18886</a>","mla":"Janik, Marian. <i>Research Data for Publication “Strong Charge-Photon Coupling in Planar Germanium Enabled by Granular Aluminium Superinductors.”</i> Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:18886\">10.15479/AT:ISTA:18886</a>."},"acknowledgement":"We acknowledge Franco De Palma, Mahya Khorramshahi, Fabian Oppliger, Thomas Reisinger, Pasquale Scarlino and Xiao Xue for helpful discussions. We thank Simon Robson for proofreading the manuscript. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication facility. This research and related results were made possible with the support of the NOMIS Foundation and the HORIZON-RIA 101069515 project. This research was funded in whole or in part by the Austrian Science Fund (FWF) DOI:10.55776/P32235, DOI:10.55776/I5060 and DOI:10.55776/P36507. For Open Access purposes, the author has applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. M.J. acknowledges funding from FellowQUTE 2024-01. I.M.P. acknowledges funding from the Deutsche Forschungsgemeinschaft (DFG – German Research Foundation) under project number 450396347 (GeHoldeQED). ICN2 acknowledges funding from Generalitat de Catalunya 2021SGR00457. We acknowledge support from CSIC Interdisciplinary Thematic Platform (PTI+) on Quantum Technologies (PTI-QTEP+). This research work has been funded by the European Commission – NextGenerationEU (Regulation EU 2020/2094), through CSIC's Quantum Technologies Platform (QTEP). ICN2 is supported by the Severo Ochoa program from Spanish MCIN/AEI (Grant No.: CEX2021-001214-S) and is funded by the CERCA Programme/Generalitat de Catalunya. Part of the present work has been performed in the framework of Universitat Autònoma de Barcelona Materials Science PhD program. AGM has received funding from Grant RYC2021-033479-I funded by MCIN/AEI/10.13039/501100011033 and by European Union NextGenerationEU/PRTR. M.B. acknowledges support from SUR Generalitat de Catalunya and the EU Social Fund; project ref. 2020 FI 00103. The authors acknowledge the use of instrumentation and the technical advice provided by the Joint Electron Microscopy Center at ALBA (JEMCA). ICN2 acknowledges funding from Grant IU16-014206 (METCAM-FIB) funded by the European Union through the European Regional Development Fund (ERDF), with the support of the Ministry of Research and Universities, Generalitat de Catalunya. ICN2 is a founding member of e-DREAM.","doi":"10.15479/AT:ISTA:18886","file":[{"file_id":"18893","access_level":"open_access","creator":"arashid","date_created":"2025-01-27T11:27:30Z","relation":"main_file","content_type":"text/plain","file_name":"readme.txt","checksum":"977dffed4bec3c7d6315aa1cbd19e8a7","file_size":1017,"date_updated":"2025-01-27T11:27:30Z","success":1},{"access_level":"open_access","creator":"arashid","date_created":"2025-01-27T11:27:35Z","relation":"main_file","file_id":"18894","file_size":33815056,"success":1,"date_updated":"2025-01-27T11:27:35Z","content_type":"application/zip","file_name":"research_data.zip","checksum":"7ab5e3e65ddf59bbf3622ace8a0cda1c"}],"oa_version":"Published Version","OA_place":"repository","project":[{"grant_number":"101069515","name":"Integrated Germanium Quantum Technology","_id":"34c0acea-11ca-11ed-8bc3-8775e10fd452"},{"grant_number":"P32235","call_identifier":"FWF","name":"Towards scalable hut wire quantum 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enabled by granular aluminium superinductors'","author":[{"id":"396A1950-F248-11E8-B48F-1D18A9856A87","orcid":"0009-0003-9037-8831","last_name":"Janik","full_name":"Janik, Marian","first_name":"Marian"}],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","contributor":[{"contributor_type":"researcher","first_name":"Kevin Etienne Robert","last_name":"Roux","id":"53f93ea2-803f-11ed-ab7e-b283135794ef"},{"id":"18777c01-896a-11ed-bdf8-e4851dc07d16","first_name":"Carla N","contributor_type":"researcher","last_name":"Borja 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M.","contributor_type":"researcher"},{"id":"38DB5788-F248-11E8-B48F-1D18A9856A87","contributor_type":"researcher","first_name":"Georgios","orcid":"0000-0001-8342-202X","last_name":"Katsaros"}],"corr_author":"1","ddc":["530"],"date_created":"2025-01-27T09:48:44Z","has_accepted_license":"1","OA_type":"gold","related_material":{"record":[{"id":"18144","relation":"used_in_publication","status":"public"},{"status":"public","relation":"used_in_publication","id":"19401"}]}},{"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","corr_author":"1","ddc":["570"],"date_created":"2025-10-14T10:24:41Z","has_accepted_license":"1","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"19566"}]},"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"page":"99","title":"The role of cyclooxygenase 1 on microglial response to inflammatory stressors","author":[{"first_name":"Florianne E","full_name":"Miteva, Florianne E","last_name":"Miteva","id":"3526230C-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"supervisor":[{"id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8635-0877","last_name":"Siegert","first_name":"Sandra","full_name":"Siegert, Sandra"}],"status":"public","file":[{"content_type":"application/pdf","checksum":"03537697be8c688d3a05cf948288e48f","file_name":"2025_Miteva_Florianne_thesis.pdf","file_size":13668588,"embargo_to":"open_access","date_updated":"2025-10-17T11:13:25Z","embargo":"2026-10-14","file_id":"20484","creator":"fschootu","access_level":"closed","relation":"main_file","date_created":"2025-10-17T11:09:11Z"},{"file_size":28991918,"date_updated":"2025-10-23T11:33:06Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_name":"2025_Miteva_florianne_thesis.docx","checksum":"df4930d7211cf9cfe1254b77204dc1d3","access_level":"closed","creator":"fschootu","date_created":"2025-10-23T11:33:06Z","relation":"source_file","file_id":"20525"}],"oa_version":"Published Version","publication_status":"published","OA_place":"publisher","article_processing_charge":"No","project":[{"grant_number":"P37131","_id":"7be82147-9f16-11ee-852c-f44682d73140","name":"Dissecting the morpho-functional relationship of microglia"}],"publisher":"Institute of Science and Technology Austria","date_published":"2025-10-14T00:00:00Z","year":"2025","alternative_title":["ISTA Thesis"],"month":"10","date_updated":"2026-05-20T06:37:12Z","_id":"20467","day":"14","file_date_updated":"2025-10-23T11:33:06Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"SSU"},{"_id":"PreCl"},{"_id":"LifeSc"}],"type":"dissertation","department":[{"_id":"GradSch"},{"_id":"SaSi"}],"citation":{"mla":"Miteva, Florianne E. <i>The Role of Cyclooxygenase 1 on Microglial Response to Inflammatory Stressors</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20467\">10.15479/AT-ISTA-20467</a>.","ama":"Miteva FE. The role of cyclooxygenase 1 on microglial response to inflammatory stressors. 2025. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20467\">10.15479/AT-ISTA-20467</a>","short":"F.E. Miteva, The Role of Cyclooxygenase 1 on Microglial Response to Inflammatory Stressors, Institute of Science and Technology Austria, 2025.","apa":"Miteva, F. E. (2025). <i>The role of cyclooxygenase 1 on microglial response to inflammatory stressors</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20467\">https://doi.org/10.15479/AT-ISTA-20467</a>","ista":"Miteva FE. 2025. The role of cyclooxygenase 1 on microglial response to inflammatory stressors. Institute of Science and Technology Austria.","ieee":"F. E. Miteva, “The role of cyclooxygenase 1 on microglial response to inflammatory stressors,” Institute of Science and Technology Austria, 2025.","chicago":"Miteva, Florianne E. “The Role of Cyclooxygenase 1 on Microglial Response to Inflammatory Stressors.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT-ISTA-20467\">https://doi.org/10.15479/AT-ISTA-20467</a>."},"degree_awarded":"PhD","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"The work presented in this Thesis was carried out at the Institute of Science and Technology\r\nAustria (ISTA), and was supported by the Austrian Science Fund (FWF) [10.55776/P37131].\r\nI would like to thank the Scientific Service Units (SSU) of ISTA for the provided resources,\r\nspecifically the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF), and the\r\nPre-Clinical Facility (PCF) team, specifically Sonja Haslinger, Claudia Gold, and Michael\r\nSchunn, for mouse colony management and support. 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Crippa for helpful discussions. This research was supported by the Scientific Service Units of ISTA through resources provided by the MIBA Machine Shop and the Nanofabrication facility. This research and related results were made possible with the support of the NOMIS Foundation, the HORIZON-RIA 101069515 project and the FWF Projects \r\nwith DOI:10.55776/F86 and DOI:10.55776/I5060. M.R.-R. acknowledges support from the Netherlands Organization of\r\n scientific Research (NWO) under Veni grant VI.Veni.212.223. The Research of S.B. and M.R.-R. was sponsored in part by the Army Research Office and was accomplished under Award Number: W911NF-23-1-0110.","citation":{"apa":"Saez Mollejo, J. (2025). Exchange anisotropies in microwave-driven singlet-triplet qubits. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:19409\">https://doi.org/10.15479/AT:ISTA:19409</a>","ista":"Saez Mollejo J. 2025. Exchange anisotropies in microwave-driven singlet-triplet qubits, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:19409\">10.15479/AT:ISTA:19409</a>.","mla":"Saez Mollejo, Jaime. <i>Exchange Anisotropies in Microwave-Driven Singlet-Triplet Qubits</i>. Institute of Science and Technology Austria, 2025, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19409\">10.15479/AT:ISTA:19409</a>.","ama":"Saez Mollejo J. Exchange anisotropies in microwave-driven singlet-triplet qubits. 2025. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:19409\">10.15479/AT:ISTA:19409</a>","short":"J. Saez Mollejo, (2025).","chicago":"Saez Mollejo, Jaime. “Exchange Anisotropies in Microwave-Driven Singlet-Triplet Qubits.” Institute of Science and Technology Austria, 2025. <a href=\"https://doi.org/10.15479/AT:ISTA:19409\">https://doi.org/10.15479/AT:ISTA:19409</a>.","ieee":"J. Saez Mollejo, “Exchange anisotropies in microwave-driven singlet-triplet qubits.” Institute of Science and Technology Austria, 2025."},"type":"research_data","department":[{"_id":"GradSch"},{"_id":"GeKa"}],"oa":1}]