---
OA_place: publisher
OA_type: diamond
_id: '19844'
abstract:
- lang: eng
  text: "Context. Rapidly rotating classical OBe stars have been proposed as the products
    of binary interactions, and the fraction of Be stars with compact companions implies
    that at least some are. However, to constrain the interaction physics spinning
    up the OBe stars, a large sample of homogeneously analyzed OBe stars with well-determined
    binary characteristics and orbital parameters are required.\r\n\r\nAims. We investigated
    the multiplicity properties of a sample of 18 Oe, 62 Be, and two Of?p stars observed
    within the BLOeM survey in the Small Magellanic Cloud. We analyzed the first nine
    epochs of spectroscopic observations obtained over approximately three months
    in 2023.\r\n\r\nMethods. Radial velocities (RVs) of all stars were measured using
    cross-correlation based on different sets of absorption and emission lines. Applying
    commonly used binarity criteria, we classified objects as binaries, binary candidates,
    and apparently single (RV stable) objects. We further inspected the spectra for
    double-lined spectroscopic binaries and cross-matched with catalogs of X-ray sources
    and photometric binaries.\r\n\r\nResults. We classify 14 OBe stars as binaries,
    and an additional 11 as binary candidates. The two Of?p stars are apparently single.
    We find two more objects that are most likely currently interacting binaries.
    Without those, the observed binary fraction for the remaining OBe sample of 78
    stars is fobs+candOBe = 0.18 ± 0.04 (fobs+candOBe = 0.32±0.05 including candidates).
    This binary fraction is less than half of that measured for OB stars in BLOeM.
    Combined with the lower fraction of SB2s, this suggests that OBe stars do indeed
    have fundamentally different present-day binary properties than OB stars. We find
    no evidence for OBe binaries with massive compact companions, in contrast to expectations
    from binary population synthesis.\r\n\r\nConclusions. Our results support the
    binary scenario as an important formation channel for OBe stars, as post-interaction
    binaries may have been disrupted or the stripped companions of OBe stars are harder
    to detect. Further observations are required to characterize the detected binaries,
    their orbital parameters, and the nature of their companions."
acknowledgement: 'The research leading to these results has received funding from
  the European Research Council (ERC) under the European Union’s Horizon 2020 and
  Horizon Europe research and innovation programme (grant agreement numbers 772225:
  MULTIPLES, and 945806) and is supported by the Deutsche Forschungsgemeinschaft (DFG,
  German Research Foundation) under Germany’s Excellence Strategy EXC 2181/1-390900948
  (the Heidelberg STRUCTURES Excellence Cluster). DMB gratefully acknowledges funding
  from UK Research and Innovation (UKRI) in the form of a Frontier Research grant
  under the UK government’s ERC Horizon Europe funding guarantee (SYMPHONY; grant
  number: EP/Y031059/1), and a Royal Society University Research Fellowship (URF;
  grant number: URF\R1\231631). RGI is funded by STFC grant ST/Y002350/1 as part of
  the BRIDGCE UK network, and thanks IReNA colleagues for stimulating discussions.
  Z.K. acknowledges support from JSPS Kakenhi Grant-in-Aid for Scientific Research
  (23K19071). IM acknowledges support from the Australian Research Council (ARC) Centre
  of Excellence for GravitationalWave Discovery (OzGrav), through project number CE230100016.
  DP acknowledges financial support by the Deutsches Zentrum für Luft und Raumfahrt
  (DLR) grant FKZ 50OR2005. DFR is thankful for the support of CAPES-Br and FAPERJ/DSC-10
  (SEI-260003/001630/2023). AACS and VR are supported by the German Deutsche Forschungsgemeinschaft
  (DFG) under Project-ID 445674056 (Emmy Noether Research Group SA4064/1-1, PI Sander).
  AACS and VR are further supported by funding from the Federal Ministry of Education
  and Research (BMBF) and the Baden-Württemberg Ministry of Science as part of the
  Excellence Strategy of the German Federal and State Governments. JIV acknowledges
  support from the European Research Council for the ERC Advanced Grant 101054731.
  LRP acknowledges support from grant PID2022-140483NB-C22 funded by MCIN/AEI/10.13039/501100011033.
  GH acknowledges support from grants PID2021-122397NB-C21/PID2022-136640NB-C22 funded
  by MCIN/AEI/FEDER/10.13039/501100011033. J.K. thanks for the support of a grant
  GA CR 22-34467S. This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (grant agreement 101164755/METAL) and was supported by the Israel Science Foundation
  (ISF) under grant number 2434/24.'
article_number: A38
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: J.
  full_name: Bodensteiner, J.
  last_name: Bodensteiner
- first_name: T.
  full_name: Shenar, T.
  last_name: Shenar
- first_name: H.
  full_name: Sana, H.
  last_name: Sana
- first_name: N.
  full_name: Britavskiy, N.
  last_name: Britavskiy
- first_name: P. A.
  full_name: Crowther, P. A.
  last_name: Crowther
- first_name: N.
  full_name: Langer, N.
  last_name: Langer
- first_name: D. J.
  full_name: Lennon, D. J.
  last_name: Lennon
- first_name: L.
  full_name: Mahy, L.
  last_name: Mahy
- first_name: L. R.
  full_name: Patrick, L. R.
  last_name: Patrick
- first_name: J. I.
  full_name: Villaseñor, J. I.
  last_name: Villaseñor
- first_name: M.
  full_name: Abdul-Masih, M.
  last_name: Abdul-Masih
- first_name: D. M.
  full_name: Bowman, D. M.
  last_name: Bowman
- first_name: A.
  full_name: De Koter, A.
  last_name: De Koter
- first_name: S. E.
  full_name: De Mink, S. E.
  last_name: De Mink
- first_name: K.
  full_name: Deshmukh, K.
  last_name: Deshmukh
- first_name: M.
  full_name: Fabry, M.
  last_name: Fabry
- first_name: A.
  full_name: Gilkis, A.
  last_name: Gilkis
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: G.
  full_name: Holgado, G.
  last_name: Holgado
- first_name: R. G.
  full_name: Izzard, R. G.
  last_name: Izzard
- first_name: S.
  full_name: Janssens, S.
  last_name: Janssens
- first_name: V. M.
  full_name: Kalari, V. M.
  last_name: Kalari
- first_name: Z.
  full_name: Keszthelyi, Z.
  last_name: Keszthelyi
- first_name: J.
  full_name: Kubát, J.
  last_name: Kubát
- first_name: I.
  full_name: Mandel, I.
  last_name: Mandel
- first_name: G.
  full_name: Maravelias, G.
  last_name: Maravelias
- first_name: L. M.
  full_name: Oskinova, L. M.
  last_name: Oskinova
- first_name: D.
  full_name: Pauli, D.
  last_name: Pauli
- first_name: V.
  full_name: Ramachandran, V.
  last_name: Ramachandran
- first_name: D. F.
  full_name: Rocha, D. F.
  last_name: Rocha
- first_name: M.
  full_name: Renzo, M.
  last_name: Renzo
- first_name: A. A.C.
  full_name: Sander, A. A.C.
  last_name: Sander
- first_name: F. R.N.
  full_name: Schneider, F. R.N.
  last_name: Schneider
- first_name: A.
  full_name: Schootemeijer, A.
  last_name: Schootemeijer
- first_name: K.
  full_name: Sen, K.
  last_name: Sen
- first_name: M.
  full_name: Stoop, M.
  last_name: Stoop
- first_name: S.
  full_name: Toonen, S.
  last_name: Toonen
- first_name: J. T.
  full_name: Van Loon, J. T.
  last_name: Van Loon
- first_name: R.
  full_name: Valli, R.
  last_name: Valli
- first_name: A.
  full_name: Vigna-Gómez, A.
  last_name: Vigna-Gómez
- first_name: J. S.
  full_name: Vink, J. S.
  last_name: Vink
- first_name: C.
  full_name: Wang, C.
  last_name: Wang
- first_name: X. T.
  full_name: Xu, X. T.
  last_name: Xu
citation:
  ama: 'Bodensteiner J, Shenar T, Sana H, et al. Binarity at LOw Metallicity (BLOeM):
    Multiplicity properties of Oe and Be stars. <i>Astronomy &#38; Astrophysics</i>.
    2025;698. doi:<a href="https://doi.org/10.1051/0004-6361/202452623">10.1051/0004-6361/202452623</a>'
  apa: 'Bodensteiner, J., Shenar, T., Sana, H., Britavskiy, N., Crowther, P. A., Langer,
    N., … Xu, X. T. (2025). Binarity at LOw Metallicity (BLOeM): Multiplicity properties
    of Oe and Be stars. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202452623">https://doi.org/10.1051/0004-6361/202452623</a>'
  chicago: 'Bodensteiner, J., T. Shenar, H. Sana, N. Britavskiy, P. A. Crowther, N.
    Langer, D. J. Lennon, et al. “Binarity at LOw Metallicity (BLOeM): Multiplicity
    Properties of Oe and Be Stars.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences,
    2025. <a href="https://doi.org/10.1051/0004-6361/202452623">https://doi.org/10.1051/0004-6361/202452623</a>.'
  ieee: 'J. Bodensteiner <i>et al.</i>, “Binarity at LOw Metallicity (BLOeM): Multiplicity
    properties of Oe and Be stars,” <i>Astronomy &#38; Astrophysics</i>, vol. 698.
    EDP Sciences, 2025.'
  ista: 'Bodensteiner J, Shenar T, Sana H, Britavskiy N, Crowther PA, Langer N, Lennon
    DJ, Mahy L, Patrick LR, Villaseñor JI, Abdul-Masih M, Bowman DM, De Koter A, De
    Mink SE, Deshmukh K, Fabry M, Gilkis A, Götberg YLL, Holgado G, Izzard RG, Janssens
    S, Kalari VM, Keszthelyi Z, Kubát J, Mandel I, Maravelias G, Oskinova LM, Pauli
    D, Ramachandran V, Rocha DF, Renzo M, Sander AAC, Schneider FRN, Schootemeijer
    A, Sen K, Stoop M, Toonen S, Van Loon JT, Valli R, Vigna-Gómez A, Vink JS, Wang
    C, Xu XT. 2025. Binarity at LOw Metallicity (BLOeM): Multiplicity properties of
    Oe and Be stars. Astronomy &#38; Astrophysics. 698, A38.'
  mla: 'Bodensteiner, J., et al. “Binarity at LOw Metallicity (BLOeM): Multiplicity
    Properties of Oe and Be Stars.” <i>Astronomy &#38; Astrophysics</i>, vol. 698,
    A38, EDP Sciences, 2025, doi:<a href="https://doi.org/10.1051/0004-6361/202452623">10.1051/0004-6361/202452623</a>.'
  short: J. Bodensteiner, T. Shenar, H. Sana, N. Britavskiy, P.A. Crowther, N. Langer,
    D.J. Lennon, L. Mahy, L.R. Patrick, J.I. Villaseñor, M. Abdul-Masih, D.M. Bowman,
    A. De Koter, S.E. De Mink, K. Deshmukh, M. Fabry, A. Gilkis, Y.L.L. Götberg, G.
    Holgado, R.G. Izzard, S. Janssens, V.M. Kalari, Z. Keszthelyi, J. Kubát, I. Mandel,
    G. Maravelias, L.M. Oskinova, D. Pauli, V. Ramachandran, D.F. Rocha, M. Renzo,
    A.A.C. Sander, F.R.N. Schneider, A. Schootemeijer, K. Sen, M. Stoop, S. Toonen,
    J.T. Van Loon, R. Valli, A. Vigna-Gómez, J.S. Vink, C. Wang, X.T. Xu, Astronomy
    &#38; Astrophysics 698 (2025).
das_tickbox: '1'
date_created: 2025-06-15T22:01:30Z
date_published: 2025-06-01T00:00:00Z
date_updated: 2026-09-16T09:14:49Z
day: '01'
ddc:
- '520'
department:
- _id: YlGo
doi: 10.1051/0004-6361/202452623
external_id:
  arxiv:
  - '2502.02641'
  isi:
  - '001497903100011'
file:
- access_level: open_access
  checksum: 51d79c82f6030180fb7c5d7ba01b2da8
  content_type: application/pdf
  creator: dernst
  date_created: 2025-06-23T07:54:57Z
  date_updated: 2025-06-23T07:54:57Z
  file_id: '19866'
  file_name: 2025_AstronomyAstrophysics_Bodensteiner.pdf
  file_size: 2404827
  relation: main_file
  success: 1
file_date_updated: 2025-06-23T07:54:57Z
fulldoi: https://doi.org/10.1051/0004-6361/202452623
has_accepted_license: '1'
intvolume: '       698'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: 'Binarity at LOw Metallicity (BLOeM): Multiplicity properties of Oe and Be
  stars'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 698
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '19842'
abstract:
- lang: eng
  text: Given the uncertain evolutionary status of blue supergiant stars, their multiplicity
    properties hold vital clues to better understand their origin and evolution. As
    part of The Binarity at LOw Metallicity (BLOeM) campaign in the Small Magellanic
    Cloud, we present a multi-epoch spectroscopic survey of 128 supergiant stars of
    spectral type B5–F5, which roughly correspond to initial masses in the 6–30 M⊙
    range. The observed binary fraction for the B5–9 supergiants is 25 ± 6% (10 ±
    4%) and 5 ± 2% (0%) for the A–F stars, which were found using a radial-velocity
    (RV) variability threshold of 5 km s−1 (10 km s−1) as a criterion for binarity.
    Accounting for observational biases, we find an intrinsic multiplicity fraction
    of less than 18% for the B5–9 stars and 8−7+9% for the AF stars, for the orbital
    periods up to 103.5 days and mass ratios (q) in the 0.1 < q < 1 range. The large
    stellar radii of these supergiant stars prevent short orbital periods, but we
    demonstrate that this effect alone cannot explain our results. We assessed the
    spectra and RV time series of the detected binary systems and find that only a
    small fraction display convincing solutions. We conclude that the multiplicity
    fractions are compromised by intrinsic stellar variability, such that the true
    multiplicity fraction may be significantly smaller. Our main conclusions from
    comparing the multiplicity properties of the B5–9- and AF-type supergiants to
    that of their less evolved counterparts is that such stars cannot be explained
    by a direct evolution from the main sequence. Furthermore, by comparing their
    multiplicity properties to red supergiant stars, we conclude that the AF supergiant
    stars are neither progenitors nor descendants of red supergiants.
acknowledgement: 'We thank Sipra Hota for kindly sharing the SMC UVIT catalogue prior
  to publication. LRP, FN. and FT acknowledge support by grants PID2019-105552RB-C41
  and PID2022-137779OB-C41 funded by MCIN/AEI/10.13039/501100011033 by “ERDF A way
  of making Europe”. LRP acknowledges support from grant PID2022-140483NB-C22 funded
  by MCIN/AEI/10.13039/501100011033. TS acknowledges support by the Israel Science
  Foundation (ISF) under grant number 0603225041. The research leading to these results
  has received funding from the European Research Council (ERC) under the European
  Union’s Horizon 2020 research and innovation programme (grant agreement numbers
  772225: MULTIPLES). DMB gratefully acknowledges support from UK Research and Innovation
  (UKRI) in the form of a Frontier Research grant under the UK government’s ERC Horizon
  Europe funding guarantee (SYMPHONY; grant number: EP/Y031059/1), and a Royal Society
  University Research Fellowship (grant number: URF\R1\231631). GGT is supported by
  the German Deutsche Forschungsgemeinschaft (DFG) under Project-ID 496854903 (SA4064/2-1,
  PI Sander). AACS is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research
  Foundation) in the form of an Emmy Noether Research Group – Project-ID 445674056
  (SA4064/1-1, PI Sander). GGT and AACS further acknowledges support from the Federal
  Ministry of Education and Research (BMBF) and the Baden-Württemberg Ministry of
  Science as part of the Excellence Strategy of the German Federal and State Governments.
  This paper benefited from discussions at the International Space Science Institute
  (ISSI) in Bern through ISSI International Team project 512 (Multiwavelength View
  on Massive Stars in the Era of Multimessenger Astronomy). DP acknowledges financial
  support by the Deutsches Zentrum für Luft und Raumfahrt (DLR) grant FKZ 50OR2005.
  JIV acknowledges support from the European Research Council for the ERC Advanced
  Grant 101054731. PAC is supported by the Science and Technology Facilities Council
  research grant ST/V000853/1 (PI. V. Dhillon). JSV is supported by Science and Technology
  Facilities Council funding under grant number ST/V000233/1. DFR is thankful for
  the support of the CAPES-Br and FAPERJ/DSC-10 (SEI-260003/001630/2023). This work
  has received funding from the European Research Council (ERC) under the European
  Union’s Horizon 2020 research and innovation programme (Grant agreement No. 945806)
  and is supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)
  under Germany’s Excellence Strategy EXC 2181/1-390900948 (the Heidelberg STRUCTURES
  Excellence Cluster).'
article_number: A39
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: L. R.
  full_name: Patrick, L. R.
  last_name: Patrick
- first_name: D. J.
  full_name: Lennon, D. J.
  last_name: Lennon
- first_name: F.
  full_name: Najarro, F.
  last_name: Najarro
- first_name: T.
  full_name: Shenar, T.
  last_name: Shenar
- first_name: J.
  full_name: Bodensteiner, J.
  last_name: Bodensteiner
- first_name: H.
  full_name: Sana, H.
  last_name: Sana
- first_name: P. A.
  full_name: Crowther, P. A.
  last_name: Crowther
- first_name: N.
  full_name: Britavskiy, N.
  last_name: Britavskiy
- first_name: N.
  full_name: Langer, N.
  last_name: Langer
- first_name: A.
  full_name: Schootemeijer, A.
  last_name: Schootemeijer
- first_name: C. J.
  full_name: Evans, C. J.
  last_name: Evans
- first_name: L.
  full_name: Mahy, L.
  last_name: Mahy
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: S. E.
  full_name: De Mink, S. E.
  last_name: De Mink
- first_name: F. R.N.
  full_name: Schneider, F. R.N.
  last_name: Schneider
- first_name: A. J.G.
  full_name: O’Grady, A. J.G.
  last_name: O’Grady
- first_name: J. I.
  full_name: Villaseñor, J. I.
  last_name: Villaseñor
- first_name: M.
  full_name: Bernini-Peron, M.
  last_name: Bernini-Peron
- first_name: D. M.
  full_name: Bowman, D. M.
  last_name: Bowman
- first_name: A.
  full_name: De Koter, A.
  last_name: De Koter
- first_name: K.
  full_name: Deshmukh, K.
  last_name: Deshmukh
- first_name: A.
  full_name: Gilkis, A.
  last_name: Gilkis
- first_name: G.
  full_name: González-Torà, G.
  last_name: González-Torà
- first_name: V. M.
  full_name: Kalari, V. M.
  last_name: Kalari
- first_name: Z.
  full_name: K̃Eszthelyi, Z.
  last_name: K̃Eszthelyi
- first_name: I.
  full_name: Mandel, I.
  last_name: Mandel
- first_name: A.
  full_name: Menon, A.
  last_name: Menon
- first_name: M.
  full_name: Moe, M.
  last_name: Moe
- first_name: L. M.
  full_name: Oskinova, L. M.
  last_name: Oskinova
- first_name: D.
  full_name: Pauli, D.
  last_name: Pauli
- first_name: M.
  full_name: Renzo, M.
  last_name: Renzo
- first_name: A. A.C.
  full_name: Sander, A. A.C.
  last_name: Sander
- first_name: K.
  full_name: Sen, K.
  last_name: Sen
- first_name: M.
  full_name: Stoop, M.
  last_name: Stoop
- first_name: J. T.
  full_name: Van Loon, J. T.
  last_name: Van Loon
- first_name: S.
  full_name: Toonen, S.
  last_name: Toonen
- first_name: F.
  full_name: Tramper, F.
  last_name: Tramper
- first_name: J. S.
  full_name: Vink, J. S.
  last_name: Vink
- first_name: C.
  full_name: Wang, C.
  last_name: Wang
citation:
  ama: 'Patrick LR, Lennon DJ, Najarro F, et al. Binarity at LOw Metallicity (BLOeM):
    The multiplicity properties and evolution of BAF-type supergiants. <i>Astronomy
    &#38; Astrophysics</i>. 2025;698. doi:<a href="https://doi.org/10.1051/0004-6361/202452949">10.1051/0004-6361/202452949</a>'
  apa: 'Patrick, L. R., Lennon, D. J., Najarro, F., Shenar, T., Bodensteiner, J.,
    Sana, H., … Wang, C. (2025). Binarity at LOw Metallicity (BLOeM): The multiplicity
    properties and evolution of BAF-type supergiants. <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202452949">https://doi.org/10.1051/0004-6361/202452949</a>'
  chicago: 'Patrick, L. R., D. J. Lennon, F. Najarro, T. Shenar, J. Bodensteiner,
    H. Sana, P. A. Crowther, et al. “Binarity at LOw Metallicity (BLOeM): The Multiplicity
    Properties and Evolution of BAF-Type Supergiants.” <i>Astronomy &#38; Astrophysics</i>.
    EDP Sciences, 2025. <a href="https://doi.org/10.1051/0004-6361/202452949">https://doi.org/10.1051/0004-6361/202452949</a>.'
  ieee: 'L. R. Patrick <i>et al.</i>, “Binarity at LOw Metallicity (BLOeM): The multiplicity
    properties and evolution of BAF-type supergiants,” <i>Astronomy &#38; Astrophysics</i>,
    vol. 698. EDP Sciences, 2025.'
  ista: 'Patrick LR, Lennon DJ, Najarro F, Shenar T, Bodensteiner J, Sana H, Crowther
    PA, Britavskiy N, Langer N, Schootemeijer A, Evans CJ, Mahy L, Götberg YLL, De
    Mink SE, Schneider FRN, O’Grady AJG, Villaseñor JI, Bernini-Peron M, Bowman DM,
    De Koter A, Deshmukh K, Gilkis A, González-Torà G, Kalari VM, K̃Eszthelyi Z, Mandel
    I, Menon A, Moe M, Oskinova LM, Pauli D, Renzo M, Sander AAC, Sen K, Stoop M,
    Van Loon JT, Toonen S, Tramper F, Vink JS, Wang C. 2025. Binarity at LOw Metallicity
    (BLOeM): The multiplicity properties and evolution of BAF-type supergiants. Astronomy
    &#38; Astrophysics. 698, A39.'
  mla: 'Patrick, L. R., et al. “Binarity at LOw Metallicity (BLOeM): The Multiplicity
    Properties and Evolution of BAF-Type Supergiants.” <i>Astronomy &#38; Astrophysics</i>,
    vol. 698, A39, EDP Sciences, 2025, doi:<a href="https://doi.org/10.1051/0004-6361/202452949">10.1051/0004-6361/202452949</a>.'
  short: L.R. Patrick, D.J. Lennon, F. Najarro, T. Shenar, J. Bodensteiner, H. Sana,
    P.A. Crowther, N. Britavskiy, N. Langer, A. Schootemeijer, C.J. Evans, L. Mahy,
    Y.L.L. Götberg, S.E. De Mink, F.R.N. Schneider, A.J.G. O’Grady, J.I. Villaseñor,
    M. Bernini-Peron, D.M. Bowman, A. De Koter, K. Deshmukh, A. Gilkis, G. González-Torà,
    V.M. Kalari, Z. K̃Eszthelyi, I. Mandel, A. Menon, M. Moe, L.M. Oskinova, D. Pauli,
    M. Renzo, A.A.C. Sander, K. Sen, M. Stoop, J.T. Van Loon, S. Toonen, F. Tramper,
    J.S. Vink, C. Wang, Astronomy &#38; Astrophysics 698 (2025).
das_tickbox: '1'
date_created: 2025-06-15T22:01:29Z
date_published: 2025-06-01T00:00:00Z
date_updated: 2026-09-16T09:11:14Z
day: '01'
ddc:
- '520'
department:
- _id: YlGo
doi: 10.1051/0004-6361/202452949
external_id:
  arxiv:
  - '2502.02644'
  isi:
  - '001497903100028'
file:
- access_level: open_access
  checksum: 93a907bf48da7e2ba7d75b53ea6011f5
  content_type: application/pdf
  creator: dernst
  date_created: 2025-06-23T07:09:38Z
  date_updated: 2025-06-23T07:09:38Z
  file_id: '19863'
  file_name: 2025_AstronomyAstrophysics_Patrick.pdf
  file_size: 2130448
  relation: main_file
  success: 1
file_date_updated: 2025-06-23T07:09:38Z
fulldoi: https://doi.org/10.1051/0004-6361/202452949
has_accepted_license: '1'
intvolume: '       698'
isi: 1
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'Binarity at LOw Metallicity (BLOeM): The multiplicity properties and evolution
  of BAF-type supergiants'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 698
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20352'
abstract:
- lang: eng
  text: "At high metallicity, a majority of massive stars have at least one close
    stellar companion. The evolution of such binaries is subject to strong interaction
    processes, which heavily impact the characteristics of their life-ending supernova
    and compact remnants. For the low-metallicity environments of high-redshift galaxies,
    constraints on the multiplicity properties of massive stars over the separation
    range leading to binary interaction are crucially missing. Here we show that the
    presence of massive stars in close binaries is ubiquitous, even at low metallicity.
    Using the Very Large Telescope, we obtained multi-epoch radial velocity measurements
    of a representative sample of 139 massive O-type stars across the Small Magellanic
    Cloud, which has a metal content of about one-fifth of the solar value. We find
    that 45% of them show radial velocity variations that demonstrate that they are
    members of close binary systems, and predominantly have orbital periods shorter
    than 1 year. Correcting for observational biases indicates that at least 70+11−6
    %  of the O stars in our sample are in close binaries, and that at least 68+7\r\n−8%
    of all O stars interact with a companion star during their lifetime. We found
    no evidence supporting a statistically significant trend of the multiplicity properties
    with metallicity. Our results indicate that multiplicity and binary interactions
    govern the evolution of massive stars and determine their cosmic feedback and
    explosive fates."
acknowledgement: 'Based on data collected at the European Southern Observatory (ESO)
  under programme ID 112.25R7. The research leading to these results has received
  funding from the European Research Council (ERC) under the European Union’s Horizon
  2020 and Horizon Europe research and innovation programme (grant agreement numbers
  772225: MULTIPLES, 772086: ASSESS and 945806: TEL-STARS, ADG101054731: Stellar-BHs-SDSS-V,
  and 101164755: METAL). This research was supported by the Israel Science Foundation
  (ISF) under grant number 0603225041. We acknowledge support from the Science and
  Technology Facilities Council (research grant ST/V000853/1 and ST/V000233/1), UK
  Research and Innovation (UKRI) and the UK government’s ERC Horizon Europe funding
  guarantee (grant number EP/Y031059/1), a Royal Society University Research Fellowship
  (grant number URF\R1\231631), a Royal Society–Science Foundation Ireland University
  Research Fellowship, the German Deutsche Forschungsgemeinschaft (Project-ID 496854903,
  445674056 and 443790621, Germany’s Excellence Strategy EXC 2181/1-390900948), the
  Klaus Tschira Foundation, the JSPS Kakenhi Grant-in-Aid for Scientific Research
  (23K19071) and international fellowships (at the Graduate school of Science, Tokyo
  University), the Australian Research Council (ARC) Centre of Excellence for Gravitational
  Wave Discovery (OzGrav; project number CE230100016), the Deutsches Zentrum für Luft
  und Raumfahrt (DLR) grants FKZ 50OR2005 and 50OR2306, Agencia Española de Investigación
  (AEI) of the Spanish Ministerio de Ciencia Innovación y Universidades (MICIU) and
  the European Regional Development Fund, FEDER and Severo Ochoa Programme (grants
  PID2021-122397NB-C21 and CEX2019-000920-S), the NextGeneration EU/PRTR and MIU (UNI/551/2021)
  trough grant Margarita Salas-UL, the CAPES-Br and FAPERJ/DSC-10 (SEI-260003/001630/2023),
  MCIN/AEI/10.13039/501100011033 by ‘ERDF A way of making Europe’ (grants PID2019-105552RB-C41
  and PID2022-137779OB-C41, PID2021-125485NB-C22, CEX2019-000918-M) funded by MCIN/AEI/10.13039/501100011033
  (State Agency for Research of the Spanish Ministry of Science and Innovation) and
  SGR-2021-01069 (AGAUR), the Spanish Government Ministerio de Ciencia e Innovación
  and Agencia Estatal de Investigación (10.13 039/501 100 011 033; grant PID2022-136
  640 NB-C22), the Consejo Superior de Investigaciones Científicas (CSIC; grant 2022-AEP
  005), the Polish National Agency for Academic Exchange (BEKKER fellowship BPN/BEK/2022/1/00106)
  and National Science Center (NCN, Poland; grant number OPUS 2021/41/B/ST9/00757),
  the ‘La Caixa’ Foundation (ID 100010434) under the fellowship code LCF/BQ/PI23/11970035,
  the Research foundation Flanders (FWO) PhD fellowship under project 11E1721N and
  senior postdoctoral fellowship under number 12ZY523N, and the Netherlands Research
  Council NWO (VIDI 203.061 grant).'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: H.
  full_name: Sana, H.
  last_name: Sana
- first_name: T.
  full_name: Shenar, T.
  last_name: Shenar
- first_name: J.
  full_name: Bodensteiner, J.
  last_name: Bodensteiner
- first_name: N.
  full_name: Britavskiy, N.
  last_name: Britavskiy
- first_name: N.
  full_name: Langer, N.
  last_name: Langer
- first_name: D. J.
  full_name: Lennon, D. J.
  last_name: Lennon
- first_name: L.
  full_name: Mahy, L.
  last_name: Mahy
- first_name: I.
  full_name: Mandel, I.
  last_name: Mandel
- first_name: S. E.
  full_name: De Mink, S. E.
  last_name: De Mink
- first_name: L. R.
  full_name: Patrick, L. R.
  last_name: Patrick
- first_name: J. I.
  full_name: Villaseñor, J. I.
  last_name: Villaseñor
- first_name: M.
  full_name: Dirickx, M.
  last_name: Dirickx
- first_name: M.
  full_name: Abdul-Masih, M.
  last_name: Abdul-Masih
- first_name: L. A.
  full_name: Almeida, L. A.
  last_name: Almeida
- first_name: F.
  full_name: Backs, F.
  last_name: Backs
- first_name: S. R.
  full_name: Berlanas, S. R.
  last_name: Berlanas
- first_name: M.
  full_name: Bernini-Peron, M.
  last_name: Bernini-Peron
- first_name: D. M.
  full_name: Bowman, D. M.
  last_name: Bowman
- first_name: V. A.
  full_name: Bronner, V. A.
  last_name: Bronner
- first_name: P. A.
  full_name: Crowther, P. A.
  last_name: Crowther
- first_name: K.
  full_name: Deshmukh, K.
  last_name: Deshmukh
- first_name: C. J.
  full_name: Evans, C. J.
  last_name: Evans
- first_name: M.
  full_name: Fabry, M.
  last_name: Fabry
- first_name: M.
  full_name: Gieles, M.
  last_name: Gieles
- first_name: A.
  full_name: Gilkis, A.
  last_name: Gilkis
- first_name: G.
  full_name: González-Torà, G.
  last_name: González-Torà
- first_name: G.
  full_name: Gräfener, G.
  last_name: Gräfener
- first_name: Ylva Louise Linsdotter
  full_name: Götberg, Ylva Louise Linsdotter
  id: d0648d0c-0f64-11ee-a2e0-dd0faa2e4f7d
  last_name: Götberg
  orcid: 0000-0002-6960-6911
- first_name: C.
  full_name: Hawcroft, C.
  last_name: Hawcroft
- first_name: V.
  full_name: Hénault-Brunet, V.
  last_name: Hénault-Brunet
- first_name: A.
  full_name: Herrero, A.
  last_name: Herrero
- first_name: G.
  full_name: Holgado, G.
  last_name: Holgado
- first_name: R. G.
  full_name: Izzard, R. G.
  last_name: Izzard
- first_name: A.
  full_name: De Koter, A.
  last_name: De Koter
- first_name: S.
  full_name: Janssens, S.
  last_name: Janssens
- first_name: C.
  full_name: Johnston, C.
  last_name: Johnston
- first_name: J.
  full_name: Josiek, J.
  last_name: Josiek
- first_name: S.
  full_name: Justham, S.
  last_name: Justham
- first_name: V. M.
  full_name: Kalari, V. M.
  last_name: Kalari
- first_name: J.
  full_name: Klencki, J.
  last_name: Klencki
- first_name: J.
  full_name: Kubát, J.
  last_name: Kubát
- first_name: B.
  full_name: Kubátová, B.
  last_name: Kubátová
- first_name: R. R.
  full_name: Lefever, R. R.
  last_name: Lefever
- first_name: J. Th
  full_name: Van Loon, J. Th
  last_name: Van Loon
- first_name: B.
  full_name: Ludwig, B.
  last_name: Ludwig
- first_name: J.
  full_name: Mackey, J.
  last_name: Mackey
- first_name: J.
  full_name: Maíz Apellániz, J.
  last_name: Maíz Apellániz
- first_name: G.
  full_name: Maravelias, G.
  last_name: Maravelias
- first_name: P.
  full_name: Marchant, P.
  last_name: Marchant
- first_name: T.
  full_name: Mazeh, T.
  last_name: Mazeh
- first_name: A.
  full_name: Menon, A.
  last_name: Menon
- first_name: M.
  full_name: Moe, M.
  last_name: Moe
- first_name: F.
  full_name: Najarro, F.
  last_name: Najarro
- first_name: L. M.
  full_name: Oskinova, L. M.
  last_name: Oskinova
- first_name: R.
  full_name: Ovadia, R.
  last_name: Ovadia
- first_name: D.
  full_name: Pauli, D.
  last_name: Pauli
- first_name: M.
  full_name: Pawlak, M.
  last_name: Pawlak
- first_name: V.
  full_name: Ramachandran, V.
  last_name: Ramachandran
- first_name: M.
  full_name: Renzo, M.
  last_name: Renzo
- first_name: D. F.
  full_name: Rocha, D. F.
  last_name: Rocha
- first_name: A. A.C.
  full_name: Sander, A. A.C.
  last_name: Sander
- first_name: F. R.N.
  full_name: Schneider, F. R.N.
  last_name: Schneider
- first_name: A.
  full_name: Schootemeijer, A.
  last_name: Schootemeijer
- first_name: E. C.
  full_name: Schösser, E. C.
  last_name: Schösser
- first_name: C.
  full_name: Schürmann, C.
  last_name: Schürmann
- first_name: K.
  full_name: Sen, K.
  last_name: Sen
- first_name: S.
  full_name: Shahaf, S.
  last_name: Shahaf
- first_name: S.
  full_name: Simón-Díaz, S.
  last_name: Simón-Díaz
- first_name: L. A.C.
  full_name: Van Son, L. A.C.
  last_name: Van Son
- first_name: M.
  full_name: Stoop, M.
  last_name: Stoop
- first_name: S.
  full_name: Toonen, S.
  last_name: Toonen
- first_name: F.
  full_name: Tramper, F.
  last_name: Tramper
- first_name: R.
  full_name: Valli, R.
  last_name: Valli
- first_name: A.
  full_name: Vigna-Gómez, A.
  last_name: Vigna-Gómez
- first_name: J. S.
  full_name: Vink, J. S.
  last_name: Vink
- first_name: C.
  full_name: Wang, C.
  last_name: Wang
- first_name: R.
  full_name: Willcox, R.
  last_name: Willcox
citation:
  ama: Sana H, Shenar T, Bodensteiner J, et al. A high fraction of close massive binary
    stars at low metallicity. <i>Nature Astronomy</i>. 2025;9:1337-1346. doi:<a href="https://doi.org/10.1038/s41550-025-02610-x">10.1038/s41550-025-02610-x</a>
  apa: Sana, H., Shenar, T., Bodensteiner, J., Britavskiy, N., Langer, N., Lennon,
    D. J., … Willcox, R. (2025). A high fraction of close massive binary stars at
    low metallicity. <i>Nature Astronomy</i>. Springer Nature. <a href="https://doi.org/10.1038/s41550-025-02610-x">https://doi.org/10.1038/s41550-025-02610-x</a>
  chicago: Sana, H., T. Shenar, J. Bodensteiner, N. Britavskiy, N. Langer, D. J. Lennon,
    L. Mahy, et al. “A High Fraction of Close Massive Binary Stars at Low Metallicity.”
    <i>Nature Astronomy</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s41550-025-02610-x">https://doi.org/10.1038/s41550-025-02610-x</a>.
  ieee: H. Sana <i>et al.</i>, “A high fraction of close massive binary stars at low
    metallicity,” <i>Nature Astronomy</i>, vol. 9. Springer Nature, pp. 1337–1346,
    2025.
  ista: Sana H, Shenar T, Bodensteiner J, Britavskiy N, Langer N, Lennon DJ, Mahy
    L, Mandel I, De Mink SE, Patrick LR, Villaseñor JI, Dirickx M, Abdul-Masih M,
    Almeida LA, Backs F, Berlanas SR, Bernini-Peron M, Bowman DM, Bronner VA, Crowther
    PA, Deshmukh K, Evans CJ, Fabry M, Gieles M, Gilkis A, González-Torà G, Gräfener
    G, Götberg YLL, Hawcroft C, Hénault-Brunet V, Herrero A, Holgado G, Izzard RG,
    De Koter A, Janssens S, Johnston C, Josiek J, Justham S, Kalari VM, Klencki J,
    Kubát J, Kubátová B, Lefever RR, Van Loon JT, Ludwig B, Mackey J, Maíz Apellániz
    J, Maravelias G, Marchant P, Mazeh T, Menon A, Moe M, Najarro F, Oskinova LM,
    Ovadia R, Pauli D, Pawlak M, Ramachandran V, Renzo M, Rocha DF, Sander AAC, Schneider
    FRN, Schootemeijer A, Schösser EC, Schürmann C, Sen K, Shahaf S, Simón-Díaz S,
    Van Son LAC, Stoop M, Toonen S, Tramper F, Valli R, Vigna-Gómez A, Vink JS, Wang
    C, Willcox R. 2025. A high fraction of close massive binary stars at low metallicity.
    Nature Astronomy. 9, 1337–1346.
  mla: Sana, H., et al. “A High Fraction of Close Massive Binary Stars at Low Metallicity.”
    <i>Nature Astronomy</i>, vol. 9, Springer Nature, 2025, pp. 1337–46, doi:<a href="https://doi.org/10.1038/s41550-025-02610-x">10.1038/s41550-025-02610-x</a>.
  short: H. Sana, T. Shenar, J. Bodensteiner, N. Britavskiy, N. Langer, D.J. Lennon,
    L. Mahy, I. Mandel, S.E. De Mink, L.R. Patrick, J.I. Villaseñor, M. Dirickx, M.
    Abdul-Masih, L.A. Almeida, F. Backs, S.R. Berlanas, M. Bernini-Peron, D.M. Bowman,
    V.A. Bronner, P.A. Crowther, K. Deshmukh, C.J. Evans, M. Fabry, M. Gieles, A.
    Gilkis, G. González-Torà, G. Gräfener, Y.L.L. Götberg, C. Hawcroft, V. Hénault-Brunet,
    A. Herrero, G. Holgado, R.G. Izzard, A. De Koter, S. Janssens, C. Johnston, J.
    Josiek, S. Justham, V.M. Kalari, J. Klencki, J. Kubát, B. Kubátová, R.R. Lefever,
    J.T. Van Loon, B. Ludwig, J. Mackey, J. Maíz Apellániz, G. Maravelias, P. Marchant,
    T. Mazeh, A. Menon, M. Moe, F. Najarro, L.M. Oskinova, R. Ovadia, D. Pauli, M.
    Pawlak, V. Ramachandran, M. Renzo, D.F. Rocha, A.A.C. Sander, F.R.N. Schneider,
    A. Schootemeijer, E.C. Schösser, C. Schürmann, K. Sen, S. Shahaf, S. Simón-Díaz,
    L.A.C. Van Son, M. Stoop, S. Toonen, F. Tramper, R. Valli, A. Vigna-Gómez, J.S.
    Vink, C. Wang, R. Willcox, Nature Astronomy 9 (2025) 1337–1346.
das_tickbox: '1'
date_created: 2025-09-14T22:01:32Z
date_published: 2025-09-02T00:00:00Z
date_updated: 2026-09-16T10:03:32Z
day: '02'
department:
- _id: YlGo
doi: 10.1038/s41550-025-02610-x
external_id:
  arxiv:
  - '2509.12488'
  isi:
  - '001568077900001'
fulldoi: https://doi.org/10.1038/s41550-025-02610-x
intvolume: '         9'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2509.12488
month: '09'
oa: 1
oa_version: Preprint
page: 1337-1346
publication: Nature Astronomy
publication_identifier:
  eissn:
  - 2397-3366
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: A high fraction of close massive binary stars at low metallicity
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 9
year: '2025'
...
---
OA_place: repository
_id: '19546'
abstract:
- lang: eng
  text: "We study the sensitivity of the eigenvectors of random matrices, showing
    that\r\neven small perturbations make the eigenvectors almost orthogonal. More\r\nprecisely,
    we consider two deformed Wigner matrices $W+D_1$, $W+D_2$ and show\r\nthat their
    bulk eigenvectors become asymptotically orthogonal as soon as\r\n$\\mathrm{Tr}(D_1-D_2)^2\\gg
    1$, or their respective energies are separated on a\r\nscale much bigger than
    the local eigenvalue spacing. Furthermore, we show that\r\nquadratic forms of
    eigenvectors of $W+D_1$, $W+D_2$ with any deterministic\r\nmatrix $A\\in\\mathbf{C}^{N\\times
    N}$ in a specific subspace of codimension one\r\nare of size $N^{-1/2}$. This
    proves a generalization of the Eigenstate\r\nThermalization Hypothesis to eigenvectors
    belonging to two different spectral\r\nfamilies."
acknowledgement: Supported by the ERC Advanced Grant “RMTBeyond” No. 101020331.
article_processing_charge: No
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Oleksii
  full_name: Kolupaiev, Oleksii
  id: 149b70d4-896a-11ed-bdf8-8c63fd44ca61
  last_name: Kolupaiev
  orcid: 0000-0003-1491-4623
citation:
  ama: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. Eigenvector decorrelation for
    random matrices. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2410.10718">10.48550/arXiv.2410.10718</a>
  apa: Cipolloni, G., Erdös, L., Henheik, S. J., &#38; Kolupaiev, O. (n.d.). Eigenvector
    decorrelation for random matrices. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2410.10718">https://doi.org/10.48550/arXiv.2410.10718</a>
  chicago: Cipolloni, Giorgio, László Erdös, Sven Joscha Henheik, and Oleksii Kolupaiev.
    “Eigenvector Decorrelation for Random Matrices.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2410.10718">https://doi.org/10.48550/arXiv.2410.10718</a>.
  ieee: G. Cipolloni, L. Erdös, S. J. Henheik, and O. Kolupaiev, “Eigenvector decorrelation
    for random matrices,” <i>arXiv</i>. .
  ista: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. Eigenvector decorrelation for
    random matrices. arXiv, <a href="https://doi.org/10.48550/arXiv.2410.10718">10.48550/arXiv.2410.10718</a>.
  mla: Cipolloni, Giorgio, et al. “Eigenvector Decorrelation for Random Matrices.”
    <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/arXiv.2410.10718">10.48550/arXiv.2410.10718</a>.
  short: G. Cipolloni, L. Erdös, S.J. Henheik, O. Kolupaiev, ArXiv (n.d.).
corr_author: '1'
date_created: 2025-04-11T08:34:49Z
date_published: 2025-01-30T00:00:00Z
date_updated: 2026-09-16T10:00:54Z
day: '30'
department:
- _id: LaEr
doi: 10.48550/arXiv.2410.10718
ec_funded: 1
external_id:
  arxiv:
  - '2410.10718'
fulldoi: https://doi.org/10.48550/arXiv.2410.10718
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2410.10718
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '19540'
    relation: dissertation_contains
    status: public
  - id: '22923'
    relation: later_version
    status: public
status: public
title: Eigenvector decorrelation for random matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '22827'
abstract:
- lang: eng
  text: Quantized training of Large Language Models (LLMs) remains an open challenge,
    as maintaining accuracy while performing all matrix multiplications in low precision
    has proven difficult. This is particularly the case when fine-tuning pre-trained
    models, which can have large weight, activation, and error (output gradient) outlier
    values that make lower-precision optimization difficult. To address this, we present
    HALO, a new quantization-aware training approach for Transformers that enables
    accurate and efficient low-precision training by combining 1) strategic placement
    of Hadamard rotations in both forward and backward passes, which mitigate outliers,
    2) high-performance kernel support, and 3) FSDP integration for low-precision
    communication. Our approach ensures that all large matrix multiplications during
    the forward and backward passes are executed in lower precision. Applied to LLaMa
    models, HALO achieves near-full-precision-equivalent results during fine-tuning
    on various tasks, while delivering up to 1.41x end-to-end speedup for full fine-tuning
    on RTX 4090 GPUs. HALO efficiently supports both standard and parameter-efficient
    fine-tuning (PEFT). Our results demonstrate the first practical approach to fully
    quantized LLM fine-tuning that maintains accuracy in INT8 and FP6 precision, while
    delivering performance benefits.
acknowledgement: "This project has received funding from the European Research Council
  (ERC) under the European\r\nUnion’s Horizon 2020 program (grant agreement PSAP,
  No. 101002047. This research also obtained\r\nfunding from the “UrbanTwin: An urban
  digital twin for climate action: Assessing policies and\r\nsolutions for energy,
  water and infrastructure” project, funded by the ETH-Domain Joint Initiative\r\nprogram
  in the Strategic Area Energy, Climate and Sustainable Environment."
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Saleh
  full_name: Ashkboos, Saleh
  last_name: Ashkboos
- first_name: Mahdi
  full_name: Nikdan, Mahdi
  id: 66374281-f394-11eb-9cf6-869147deecc0
  last_name: Nikdan
- first_name: Soroush
  full_name: Tabesh, Soroush
  id: 06000900-6068-11ef-8d61-c2472ef2e752
  last_name: Tabesh
  orcid: 0009-0003-4119-6281
- first_name: Roberto
  full_name: Lopez Castro, Roberto
  id: 18495c31-fb57-11ef-ba0d-c290e10e394e
  last_name: Lopez Castro
- first_name: Torsten
  full_name: Hoefler, Torsten
  last_name: Hoefler
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Ashkboos S, Nikdan M, Tabesh S, Lopez Castro R, Hoefler T, Alistarh D-A. HALO:
    Hadamard-assisted lower-precision optimization for LLMs. In: <i>39th Conference
    on Neural Information Processing Systems</i>. Vol 38. Neural Information Processing
    Systems Foundation; 2025:131755-131780. doi:<a href="https://doi.org/10.52202/085713-3966">10.52202/085713-3966</a>'
  apa: 'Ashkboos, S., Nikdan, M., Tabesh, S., Lopez Castro, R., Hoefler, T., &#38;
    Alistarh, D.-A. (2025). HALO: Hadamard-assisted lower-precision optimization for
    LLMs. In <i>39th Conference on Neural Information Processing Systems</i> (Vol.
    38, pp. 131755–131780). San Diego, CA, United States: Neural Information Processing
    Systems Foundation. <a href="https://doi.org/10.52202/085713-3966">https://doi.org/10.52202/085713-3966</a>'
  chicago: 'Ashkboos, Saleh, Mahdi Nikdan, Soroush Tabesh, Roberto Lopez Castro, Torsten
    Hoefler, and Dan-Adrian Alistarh. “HALO: Hadamard-Assisted Lower-Precision Optimization
    for LLMs.” In <i>39th Conference on Neural Information Processing Systems</i>,
    38:131755–80. Neural Information Processing Systems Foundation, 2025. <a href="https://doi.org/10.52202/085713-3966">https://doi.org/10.52202/085713-3966</a>.'
  ieee: 'S. Ashkboos, M. Nikdan, S. Tabesh, R. Lopez Castro, T. Hoefler, and D.-A.
    Alistarh, “HALO: Hadamard-assisted lower-precision optimization for LLMs,” in
    <i>39th Conference on Neural Information Processing Systems</i>, San Diego, CA,
    United States, 2025, vol. 38, pp. 131755–131780.'
  ista: 'Ashkboos S, Nikdan M, Tabesh S, Lopez Castro R, Hoefler T, Alistarh D-A.
    2025. HALO: Hadamard-assisted lower-precision optimization for LLMs. 39th Conference
    on Neural Information Processing Systems. NeurIPS: Neural Information Processing
    Systems, Advances in Neural Information Processing Systems, vol. 38, 131755–131780.'
  mla: 'Ashkboos, Saleh, et al. “HALO: Hadamard-Assisted Lower-Precision Optimization
    for LLMs.” <i>39th Conference on Neural Information Processing Systems</i>, vol.
    38, Neural Information Processing Systems Foundation, 2025, pp. 131755–80, doi:<a
    href="https://doi.org/10.52202/085713-3966">10.52202/085713-3966</a>.'
  short: S. Ashkboos, M. Nikdan, S. Tabesh, R. Lopez Castro, T. Hoefler, D.-A. Alistarh,
    in:, 39th Conference on Neural Information Processing Systems, Neural Information
    Processing Systems Foundation, 2025, pp. 131755–131780.
conference:
  end_date: 2025-12-07
  location: San Diego, CA, United States
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2025-12-02
das_tickbox: '0'
date_created: 2026-09-06T22:02:00Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-09-17T06:39:18Z
day: '01'
department:
- _id: DaAl
- _id: GradSch
doi: 10.52202/085713-3966
external_id:
  arxiv:
  - '2501.02625'
fulldoi: https://doi.org/10.52202/085713-3966
intvolume: '        38'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2501.02625
month: '12'
oa: 1
oa_version: Preprint
page: 131755-131780
publication: 39th Conference on Neural Information Processing Systems
publication_identifier:
  eissn:
  - 1049-5258
  isbn:
  - '9798331338275'
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: no
title: 'HALO: Hadamard-assisted lower-precision optimization for LLMs'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '22832'
abstract:
- lang: eng
  text: "In many scientific experiments, the data annotating cost constraints the
    pace\r\nfor testing novel hypotheses. Yet, modern machine learning pipelines offer
    a\r\npromising solution—provided their predictions yield correct conclusions.
    We\r\nfocus on Prediction-Powered Causal Inferences (PPCI), i.e., estimating the\r\ntreatment
    effect in an unlabeled target experiment, relying on training data with\r\nthe
    same outcome annotated but potentially different treatment or effect modifiers.\r\nWe
    first show that conditional calibration guarantees valid PPCI at population\r\nlevel.
    Then, we introduce a sufficient representation constraint transferring validity\r\nacross
    experiments, which we propose to enforce in practice in Deconfounded\r\nEmpirical
    Risk Minimization, our new model-agnostic training objective. We\r\nvalidate our
    method on synthetic and real-world scientific data, solving impossible\r\nproblem
    instances for Empirical Risk Minimization even with standard invariance\r\nconstraints.
    In particular, for the first time, we achieve valid causal inference\r\non a scientific
    experiment with complex recording and no human annotations,\r\nfine-tuning a foundational
    model on our similar annotated experiment."
acknowledgement: "We thank the Causal Learning and Artificial Intelligence group at
  ISTA for the continuous feedback\r\non the project and valuable discussions. We
  thank the Social Immunity group at ISTA, particularly\r\nJinook Oh, for the annotation
  program and Michaela Hoenigsberger for supporting our ecological\r\nexperiment.
  Riccardo Cadei is supported by a Google Research Scholar Award and a Google Initiated\r\nGift
  to Francesco Locatello. This research was funded in part by the Austrian Science
  Fund (FWF)\r\n10.55776/COE12). It was further partially supported by the ISTA Interdisciplinary
  Project Committee\r\nfor the collaborative project “ALED” between Francesco Locatello
  and Sylvia Cremer. For open\r\naccess purposes, the author has applied a CC BY public
  copyright license to any author accepted\r\nmanuscript version arising from this
  submission.\r\n"
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Riccardo
  full_name: Cadei, Riccardo
  id: 0fa8b76f-72f0-11ef-b75a-a5da96e5ad6b
  last_name: Cadei
- first_name: Ilker
  full_name: Demirel, Ilker
  last_name: Demirel
- first_name: Piersilvio
  full_name: De Bartolomeis, Piersilvio
  last_name: De Bartolomeis
- first_name: Lukas
  full_name: Lindorfer, Lukas
  id: 85f0e6d3-06b3-11ec-8982-8c5049fa4455
  last_name: Lindorfer
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Cordelia
  full_name: Schmid, Cordelia
  last_name: Schmid
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
citation:
  ama: 'Cadei R, Demirel I, De Bartolomeis P, et al. Prediction-Powered Causal Inferences.
    In: <i>39th Conference on Neural Information Processing Systems</i>. Vol 38. Neural
    Information Processing Systems Foundation; 2025:82200-82229. doi:<a href="https://doi.org/10.52202/085713-2479">10.52202/085713-2479</a>'
  apa: 'Cadei, R., Demirel, I., De Bartolomeis, P., Lindorfer, L., Cremer, S., Schmid,
    C., &#38; Locatello, F. (2025). Prediction-Powered Causal Inferences. In <i>39th
    Conference on Neural Information Processing Systems</i> (Vol. 38, pp. 82200–82229).
    San Diego, CA, United States: Neural Information Processing Systems Foundation.
    <a href="https://doi.org/10.52202/085713-2479">https://doi.org/10.52202/085713-2479</a>'
  chicago: Cadei, Riccardo, Ilker Demirel, Piersilvio De Bartolomeis, Lukas Lindorfer,
    Sylvia Cremer, Cordelia Schmid, and Francesco Locatello. “Prediction-Powered Causal
    Inferences.” In <i>39th Conference on Neural Information Processing Systems</i>,
    38:82200–229. Neural Information Processing Systems Foundation, 2025. <a href="https://doi.org/10.52202/085713-2479">https://doi.org/10.52202/085713-2479</a>.
  ieee: R. Cadei <i>et al.</i>, “Prediction-Powered Causal Inferences,” in <i>39th
    Conference on Neural Information Processing Systems</i>, San Diego, CA, United
    States, 2025, vol. 38, pp. 82200–82229.
  ista: 'Cadei R, Demirel I, De Bartolomeis P, Lindorfer L, Cremer S, Schmid C, Locatello
    F. 2025. Prediction-Powered Causal Inferences. 39th Conference on Neural Information
    Processing Systems. NeurIPS: Neural Information Processing Systems, Advances in
    Neural Information Processing Systems, vol. 38, 82200–82229.'
  mla: Cadei, Riccardo, et al. “Prediction-Powered Causal Inferences.” <i>39th Conference
    on Neural Information Processing Systems</i>, vol. 38, Neural Information Processing
    Systems Foundation, 2025, pp. 82200–29, doi:<a href="https://doi.org/10.52202/085713-2479">10.52202/085713-2479</a>.
  short: R. Cadei, I. Demirel, P. De Bartolomeis, L. Lindorfer, S. Cremer, C. Schmid,
    F. Locatello, in:, 39th Conference on Neural Information Processing Systems, Neural
    Information Processing Systems Foundation, 2025, pp. 82200–82229.
conference:
  end_date: 2025-12-07
  location: San Diego, CA, United States
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2025-12-02
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: "We share all the code implementation in the supplementary
  material.\r\nOur new experimental ecology dataset preview is anonymously shared
  on Figshare at\r\nhttps://figshare.com/s/9a490b6f6eeebd73350b. We further rely on
  ISTAnt dataset publicly\r\navailable at https://doi.org/10.6084/m9.figshare.26484934.v2.
  The synthetic experiments\r\non CausalMNIST relies on MNIST dataset LeCun [1998],
  publicly available. Additional\r\nexperimental details are reported in Section 5
  and Appendices B-C."
date_created: 2026-09-06T22:02:01Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-09-17T06:56:40Z
day: '01'
department:
- _id: FrLo
- _id: GradSch
- _id: SyCr
doi: 10.52202/085713-2479
external_id:
  arxiv:
  - '2502.06343'
fulldoi: https://doi.org/10.52202/085713-2479
intvolume: '        38'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2502.06343
month: '12'
oa: 1
oa_version: Preprint
page: 82200-82229
project:
- _id: a392d8f0-b034-11f1-b88e-d3025c6734f6
  grant_number: COE12
  name: Bilateral Artificial Intelligence (Locatello)
publication: 39th Conference on Neural Information Processing Systems
publication_identifier:
  isbn:
  - '9798331338275'
  issn:
  - 1049-5258
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Prediction-Powered Causal Inferences
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2025'
...
---
_id: '22831'
abstract:
- lang: eng
  text: "Neural models learn representations of high-dimensional data on low-dimensional\r\nmanifolds.
    Multiple factors, including stochasticities in the training process, model\r\narchitectures,
    and additional inductive biases, may induce different representations,\r\neven
    when learning the same task on the same data. However, it has recently been\r\nshown
    that when a latent structure is shared between distinct latent spaces, relative\r\ndistances
    between representations can be preserved, up to distortions. Building\r\non this
    idea, we demonstrate that exploiting the differential-geometric structure of\r\nlatent
    spaces of neural models, it is possible to capture precisely the transformations\r\nbetween
    representational spaces trained on similar data distributions. Specifically,\r\nwe
    assume that distinct neural models parametrize approximately the same underlying
    manifold, and introduce a representation based on the pullback metric\r\nthat
    captures the intrinsic structure of the latent space, while scaling efficiently\r\nto
    large models. We validate experimentally our method on model stitching and\r\nretrieval
    tasks, covering autoencoders and vision foundation discriminative models,\r\nacross
    diverse architectures, datasets, pretraining schemes and modalities. Code is\r\navailable
    at https://github.com/marc0git/RelativeGeodesics."
acknowledgement: "We thank Gregor Krzmanc, German Magai, Vital Fernandez for insightful
  discussions in the early\r\nstages of the project. HY was supported by the Research
  Council of Finland Flagship programme:\r\nFinnish Center for Artificial Intelligence
  FCAI. HY wishes to acknowledge CSC - IT Center for\r\nScience, Finland, for computational
  resources. GA was supported by the DFF Sapere Aude Starting\r\nGrant “GADL”. SH
  was supported by a research grant (42062) from VILLUM FONDEN and partly\r\nfunded
  by the Novo Nordisk Foundation through the Center for Basic Research in Life Science\r\n(NNF20OC0062606).
  SH received funding from the European Research Council (ERC) under the\r\nEuropean
  Union’s Horizon Programme (grant agreement 101125003). MF is supported by the MSCA\r\nIST-Bridge
  fellowship which has received funding from the European Union’s Horizon 2020 research\r\nand
  innovation program under the Marie Skłodowska-Curie grant agreement No 101034413."
alternative_title:
- Advances in Neural Information Processing Systems
article_processing_charge: No
arxiv: 1
author:
- first_name: Hanlin
  full_name: Yu, Hanlin
  last_name: Yu
- first_name: Berfin
  full_name: Inal, Berfin
  last_name: Inal
- first_name: Georgios
  full_name: Arvanitidis, Georgios
  last_name: Arvanitidis
- first_name: Søren
  full_name: Hauberg, Søren
  last_name: Hauberg
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Marco
  full_name: Fumero, Marco
  id: 1c1593eb-393f-11ef-bb8e-ab4f1e979650
  last_name: Fumero
citation:
  ama: 'Yu H, Inal B, Arvanitidis G, Hauberg S, Locatello F, Fumero M. Connecting
    neural models latent geometries with relative geodesic representations. In: <i>39th
    Conference on Neural Information Processing Systems</i>. Vol 38. Neural Information
    Processing Systems Foundation; 2025:125316-125360. doi:<a href="https://doi.org/10.52202/085713-3769">10.52202/085713-3769</a>'
  apa: 'Yu, H., Inal, B., Arvanitidis, G., Hauberg, S., Locatello, F., &#38; Fumero,
    M. (2025). Connecting neural models latent geometries with relative geodesic representations.
    In <i>39th Conference on Neural Information Processing Systems</i> (Vol. 38, pp.
    125316–125360). San Diego, CA, United States: Neural Information Processing Systems
    Foundation. <a href="https://doi.org/10.52202/085713-3769">https://doi.org/10.52202/085713-3769</a>'
  chicago: Yu, Hanlin, Berfin Inal, Georgios Arvanitidis, Søren Hauberg, Francesco
    Locatello, and Marco Fumero. “Connecting Neural Models Latent Geometries with
    Relative Geodesic Representations.” In <i>39th Conference on Neural Information
    Processing Systems</i>, 38:125316–60. Neural Information Processing Systems Foundation,
    2025. <a href="https://doi.org/10.52202/085713-3769">https://doi.org/10.52202/085713-3769</a>.
  ieee: H. Yu, B. Inal, G. Arvanitidis, S. Hauberg, F. Locatello, and M. Fumero, “Connecting
    neural models latent geometries with relative geodesic representations,” in <i>39th
    Conference on Neural Information Processing Systems</i>, San Diego, CA, United
    States, 2025, vol. 38, pp. 125316–125360.
  ista: 'Yu H, Inal B, Arvanitidis G, Hauberg S, Locatello F, Fumero M. 2025. Connecting
    neural models latent geometries with relative geodesic representations. 39th Conference
    on Neural Information Processing Systems. NeurIPS: Neural Information Processing
    Systems, Advances in Neural Information Processing Systems, vol. 38, 125316–125360.'
  mla: Yu, Hanlin, et al. “Connecting Neural Models Latent Geometries with Relative
    Geodesic Representations.” <i>39th Conference on Neural Information Processing
    Systems</i>, vol. 38, Neural Information Processing Systems Foundation, 2025,
    pp. 125316–60, doi:<a href="https://doi.org/10.52202/085713-3769">10.52202/085713-3769</a>.
  short: H. Yu, B. Inal, G. Arvanitidis, S. Hauberg, F. Locatello, M. Fumero, in:,
    39th Conference on Neural Information Processing Systems, Neural Information Processing
    Systems Foundation, 2025, pp. 125316–125360.
conference:
  end_date: 2025-12-07
  location: San Diego, CA, United States
  name: 'NeurIPS: Neural Information Processing Systems'
  start_date: 2025-12-02
corr_author: '1'
das_tickbox: '0'
date_created: 2026-09-06T22:02:01Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-09-17T07:09:28Z
day: '01'
department:
- _id: FrLo
doi: 10.52202/085713-3769
ec_funded: 1
external_id:
  arxiv:
  - '2506.01599'
fulldoi: https://doi.org/10.52202/085713-3769
intvolume: '        38'
language:
- iso: eng
month: '12'
oa_version: None
page: 125316-125360
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: 39th Conference on Neural Information Processing Systems
publication_identifier:
  eissn:
  - 1049-5258
  isbn:
  - '9798331338275'
publication_status: published
publisher: Neural Information Processing Systems Foundation
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: ' https://github.com/marc0git/RelativeGeodesics'
researchdata_availability: yes
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Connecting neural models latent geometries with relative geodesic representations
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 38
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '22929'
abstract:
- lang: eng
  text: The circle method has been successfully used over the last century to study
    rational points on hypersurfaces. More recently, a version of the method over
    function fields, combined with spreading out techniques, has led to a range of
    results about moduli spaces of rational curves on hypersurfaces. In this paper
    a version of the circle method is implemented in the setting of the Grothendieck
    ring of varieties. This allows us to approximate the classes of these moduli spaces
    directly, without relying on point counting, and leads to a deeper understanding
    of their geometry.
- lang: fre
  text: "La méthode du cercle a été utilisée avec succès au cours du siècle dernier
    pour l’étude\r\ndes points rationnels sur les hypersurfaces. Plus récemment, une
    version fonctionnelle de cette méthode,\r\ncombinée à des techniques d’étalement,
    a mené à une série de résultats sur les espaces de modules de\r\ncourbes sur les
    hypersurfaces. Dans cet article on implémente une version de la méthode du cercle
    dans\r\nle cadre de l’anneau de Grothendieck des variétés. Cela permet d’approximer
    les classes de ces espaces\r\nde modules directement, sans recours au comptage
    de points, ce qui donne accès à une compréhension\r\nplus profonde de leur géométrie."
acknowledgement: "The authors are grateful to Yohan Brunebarbe, Tom Burel, Antoine\r\nChambert-Loir,
  Loïs Faisant, Mirko Mauri and Will Sawin for useful comments. Thanks are\r\nalso
  due to the anonymous referees for numerous helpful remarks. M.B. received funding\r\nfrom
  the European Union’s Horizon 2020 research and innovation programme under the\r\nMarie
  Skłodowska-Curie Grant agreement No. 893012. T.B. was supported by a FWF grant\r\n(DOI
  10.55776/P36278) and by a grant from the Institute for Advanced Study School of\r\nMathematics."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Margaret
  full_name: Bilu, Margaret
  id: 98C47862-10D5-11EA-BEDD-0F6F3DDC885E
  last_name: Bilu
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
citation:
  ama: Bilu M, Browning TD. A motivic circle method. <i>Annales Scientifiques de l’École
    Normale Supérieure</i>. 2025;58(5):1179-1242. doi:<a href="https://doi.org/10.24033/asens.2628">10.24033/asens.2628</a>
  apa: Bilu, M., &#38; Browning, T. D. (2025). A motivic circle method. <i>Annales
    Scientifiques de l’École Normale Supérieure</i>. Société Mathématique de France.
    <a href="https://doi.org/10.24033/asens.2628">https://doi.org/10.24033/asens.2628</a>
  chicago: Bilu, Margaret, and Timothy D Browning. “A Motivic Circle Method.” <i>Annales
    Scientifiques de l’École Normale Supérieure</i>. Société Mathématique de France,
    2025. <a href="https://doi.org/10.24033/asens.2628">https://doi.org/10.24033/asens.2628</a>.
  ieee: M. Bilu and T. D. Browning, “A motivic circle method,” <i>Annales Scientifiques
    de l’École Normale Supérieure</i>, vol. 58, no. 5. Société Mathématique de France,
    pp. 1179–1242, 2025.
  ista: Bilu M, Browning TD. 2025. A motivic circle method. Annales Scientifiques
    de l’École Normale Supérieure. 58(5), 1179–1242.
  mla: Bilu, Margaret, and Timothy D. Browning. “A Motivic Circle Method.” <i>Annales
    Scientifiques de l’École Normale Supérieure</i>, vol. 58, no. 5, Société Mathématique
    de France, 2025, pp. 1179–242, doi:<a href="https://doi.org/10.24033/asens.2628">10.24033/asens.2628</a>.
  short: M. Bilu, T.D. Browning, Annales Scientifiques de l’École Normale Supérieure
    58 (2025) 1179–1242.
corr_author: '1'
das_tickbox: '0'
date_created: 2026-09-13T22:01:57Z
date_published: 2025-05-01T00:00:00Z
date_updated: 2026-09-17T08:22:39Z
day: '01'
department:
- _id: TiBr
doi: 10.24033/asens.2628
ec_funded: 1
external_id:
  arxiv:
  - '2304.09645'
fulldoi: https://doi.org/10.24033/asens.2628
intvolume: '        58'
issue: '5'
keyword:
- Circle method
- moduli spaces of curves
- hypersurfaces
- Grothendieck ring of varieties
- motivic integration
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2304.09645
month: '05'
oa: 1
oa_version: Preprint
page: 1179-1242
project:
- _id: 05A4F6F0-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '893012'
  name: A motivic circle method
- _id: bd8a4fdc-d553-11ed-ba76-80a0167441a3
  grant_number: P36278
  name: Rational curves via function field analytic number theory
publication: Annales Scientifiques de l’École Normale Supérieure
publication_identifier:
  eissn:
  - 1873-2151
  issn:
  - 0012-9593
publication_status: published
publisher: Société Mathématique de France
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: A motivic circle method
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 58
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '18074'
abstract:
- lang: eng
  text: The Aharonov–Casher theorem is a result on the number of the so-called zero
    modes of a system described by the magnetic Pauli operator in R2. In this paper
    we address the same question for the Dirac operator on a flat two-dimensional
    manifold with boundary and Atiyah–Patodi–Singer boundary condition. More concretely
    we are interested in the plane and a disc with a finite number of circular holes
    cut out. We consider a smooth compactly supported magnetic field on the manifold
    and an arbitrary magnetic field inside the holes.
acknowledgement: "First and foremost I am grateful to Jan Philip Solovej for fruitful
  meetings during (and after) my PhD programme, when this work was done. Further I
  would like to thank Joshua Hunt, Anna Sisak, Jakub Löwit, Błażej Ruba, Volodymir
  Riabov, Lukas Schimmer and Georgios Koutentakis for valuable discussions. Many thanks
  belong to Rafael Benguria for hosting my visit, during which some of the work has
  been done. I am also grateful to Marina Prokhorova who first initiated the discussion
  of this project topic and to Annemarie Luger for her valuable comments during my
  PhD defence and in particular pointing out the qualitative difference in our two
  main results. I would like to acknowledge support for research on this paper from
  VILLUM FONDEN through the QMATH Centre of Excellence grant. nr. 10059. This project
  also received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement No 101034413. I am grateful
  to the two reviewers for reading carefully my manuscript and pointing out several
  issues contributing thus significantly to the readability and clarity of this paper.\r\nOpen
  access funding provided by Institute of Science and Technology (IST Austria)."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Marie
  full_name: Fialova, Marie
  id: e9c9844d-9e21-11ec-b482-f96fc09f7c4d
  last_name: Fialova
citation:
  ama: Fialova M. Aharonov–Casher theorems for Dirac operators on manifolds with boundary
    and APS boundary condition. <i>Annales Henri Poincare</i>. 2025;26:2859-2900.
    doi:<a href="https://doi.org/10.1007/s00023-024-01482-7">10.1007/s00023-024-01482-7</a>
  apa: Fialova, M. (2025). Aharonov–Casher theorems for Dirac operators on manifolds
    with boundary and APS boundary condition. <i>Annales Henri Poincare</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00023-024-01482-7">https://doi.org/10.1007/s00023-024-01482-7</a>
  chicago: Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds
    with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>. Springer
    Nature, 2025. <a href="https://doi.org/10.1007/s00023-024-01482-7">https://doi.org/10.1007/s00023-024-01482-7</a>.
  ieee: M. Fialova, “Aharonov–Casher theorems for Dirac operators on manifolds with
    boundary and APS boundary condition,” <i>Annales Henri Poincare</i>, vol. 26.
    Springer Nature, pp. 2859–2900, 2025.
  ista: Fialova M. 2025. Aharonov–Casher theorems for Dirac operators on manifolds
    with boundary and APS boundary condition. Annales Henri Poincare. 26, 2859–2900.
  mla: Fialova, Marie. “Aharonov–Casher Theorems for Dirac Operators on Manifolds
    with Boundary and APS Boundary Condition.” <i>Annales Henri Poincare</i>, vol.
    26, Springer Nature, 2025, pp. 2859–900, doi:<a href="https://doi.org/10.1007/s00023-024-01482-7">10.1007/s00023-024-01482-7</a>.
  short: M. Fialova, Annales Henri Poincare 26 (2025) 2859–2900.
corr_author: '1'
das_tickbox: '0'
date_created: 2024-09-15T22:01:42Z
date_published: 2025-08-01T00:00:00Z
date_updated: 2026-09-17T11:06:35Z
day: '01'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s00023-024-01482-7
ec_funded: 1
external_id:
  arxiv:
  - '2304.13373'
  isi:
  - '001304370000001'
file:
- access_level: open_access
  checksum: d8d2d6dbce293c9ee6eaa9262e597147
  content_type: application/pdf
  creator: dernst
  date_created: 2025-08-05T11:24:25Z
  date_updated: 2025-08-05T11:24:25Z
  file_id: '20124'
  file_name: 2025_AnnalesHenriPoincare_Fialova.pdf
  file_size: 728124
  relation: main_file
  success: 1
file_date_updated: 2025-08-05T11:24:25Z
fulldoi: https://doi.org/10.1007/s00023-024-01482-7
has_accepted_license: '1'
intvolume: '        26'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 2859-2900
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
researchdata_availability: no
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Aharonov–Casher theorems for Dirac operators on manifolds with boundary and
  APS boundary condition
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 26
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '17293'
abstract:
- lang: eng
  text: Voltage-gated CaV2.1 (P/Q-type) Ca2+ channels play a crucial role in regulating
    neurotransmitter release, thus contributing to synaptic plasticity and to processes
    such as learning and memory. Despite their recognized importance in neural function,
    there is limited information on their potential involvement in neurodegenerative
    conditions such as Alzheimer's disease (AD). Here, we aimed to explore the impact
    of AD pathology on the density and nanoscale compartmentalization of CaV2.1 channels
    in the hippocampus in association with GABAB receptors. Histoblotting experiments
    showed that the density of CaV2.1 channel was significantly reduced in the hippocampus
    of APP/PS1 mice in a laminar-dependent manner. CaV2.1 channel was enriched in
    the active zone of the axon terminals and was present at a very low density over
    the surface of dendritic tree of the CA1 pyramidal cells, as shown by quantitative
    SDS-digested freeze-fracture replica labelling (SDS-FRL). In APP/PS1 mice, the
    density of CaV2.1 channel in the active zone was significantly reduced in the
    strata radiatum and lacunosum-moleculare, while it remained unaltered in the stratum
    oriens. The decline in Cav2.1 channel density was found to be associated with
    a corresponding impairment in the GABAergic synaptic function, as evidenced by
    electrophysiological experiments carried out in the hippocampus of APP/PS1 mice.
    Remarkably, double SDS-FRL showed a co-clustering of CaV2.1 channel and GABAB1
    receptor in nanodomains (~40–50 nm) in wild type mice, while in APP/PS1 mice this
    nanoarchitecture was absent. Together, these findings suggest that the AD pathology-induced
    reduction in CaV2.1 channel density and CaV2.1-GABAB1 de-clustering may play a
    role in the synaptic transmission alterations shown in the AD hippocampus. Therefore,
    uncovering these layer-dependent changes in P/Q calcium currents associated with
    AD pathology can benefit the development of future strategies for AD management.
acknowledgement: "Funding sources were Spanish Ministerio de Economía y Competitividad,
  Junta de Comunidades de Castilla-La Mancha (Spain), Life Science Innovation Center
  at University of Fukui and German Research Foundation.\r\nGrants RTI2018-095812-B-I00
  and PID2021-125875OB-I00 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A
  way of making Europe” to Rafael Luján. This study was also supported by a grant
  from Junta de Comunidades de Castilla-La Mancha (SBPLY/17/180501/000229 and SBPLY/21/180501/000064)
  and Universidad de Castilla-La Mancha (2023-GRIN-34187) to Rafael Luján, and Life
  Science Innovation Center (Research and Education Program for Life Science) at University
  of Fukui and JSPS KAKENHI Grant Numbers 16H04662, 17K19446, 18H05120 to Yugo Fukazawa
  and Margarita Salas fellowship from Ministerio de Universidades and Universidad
  de Castilla-La Mancha to Alejandro Martín-Belmonte. German Research Foundation (DFG
  FOR 2143) and BIOSS-2 to Akos Kulik."
article_number: e13279
article_processing_charge: Yes
article_type: original
author:
- first_name: Alejandro
  full_name: Martín‐Belmonte, Alejandro
  last_name: Martín‐Belmonte
- first_name: Carolina
  full_name: Aguado, Carolina
  last_name: Aguado
- first_name: Rocío
  full_name: Alfaro‐Ruiz, Rocío
  last_name: Alfaro‐Ruiz
- first_name: Akos
  full_name: Kulik, Akos
  last_name: Kulik
- first_name: Luis
  full_name: de la Ossa, Luis
  last_name: de la Ossa
- first_name: Ana Esther
  full_name: Moreno‐Martínez, Ana Esther
  last_name: Moreno‐Martínez
- first_name: Samuel
  full_name: Alberquilla, Samuel
  last_name: Alberquilla
- first_name: Lucía
  full_name: García‐Carracedo, Lucía
  last_name: García‐Carracedo
- first_name: Miriam
  full_name: Fernández, Miriam
  last_name: Fernández
- first_name: Ana
  full_name: Fajardo‐Serrano, Ana
  last_name: Fajardo‐Serrano
- first_name: Ester
  full_name: Aso, Ester
  last_name: Aso
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Eduardo D.
  full_name: Martín, Eduardo D.
  last_name: Martín
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Francisco
  full_name: Ciruela, Francisco
  last_name: Ciruela
- first_name: Rafael
  full_name: Luján, Rafael
  last_name: Luján
citation:
  ama: 'Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, et al. Nanoarchitecture of CaV&#62;2.1
    channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology.
    <i>Brain Pathology</i>. 2025;35(2). doi:<a href="https://doi.org/10.1111/bpa.13279">10.1111/bpa.13279</a>'
  apa: 'Martín‐Belmonte, A., Aguado, C., Alfaro‐Ruiz, R., Kulik, A., de la Ossa, L.,
    Moreno‐Martínez, A. E., … Luján, R. (2025). Nanoarchitecture of CaV&#62;2.1 channels
    and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology. <i>Brain
    Pathology</i>. Wiley. <a href="https://doi.org/10.1111/bpa.13279">https://doi.org/10.1111/bpa.13279</a>'
  chicago: 'Martín‐Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro‐Ruiz, Akos Kulik,
    Luis de la Ossa, Ana Esther Moreno‐Martínez, Samuel Alberquilla, et al. “Nanoarchitecture
    of CaV&#62;2.1 Channels and GABAB Receptors in the Mouse Hippocampus: Impact of
    APP/PS1 Pathology.” <i>Brain Pathology</i>. Wiley, 2025. <a href="https://doi.org/10.1111/bpa.13279">https://doi.org/10.1111/bpa.13279</a>.'
  ieee: 'A. Martín‐Belmonte <i>et al.</i>, “Nanoarchitecture of CaV&#62;2.1 channels
    and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology,” <i>Brain
    Pathology</i>, vol. 35, no. 2. Wiley, 2025.'
  ista: 'Martín‐Belmonte A, Aguado C, Alfaro‐Ruiz R, Kulik A, de la Ossa L, Moreno‐Martínez
    AE, Alberquilla S, García‐Carracedo L, Fernández M, Fajardo‐Serrano A, Aso E,
    Shigemoto R, Martín ED, Fukazawa Y, Ciruela F, Luján R. 2025. Nanoarchitecture
    of CaV&#62;2.1 channels and GABAB receptors in the mouse hippocampus: Impact of
    APP/PS1 pathology. Brain Pathology. 35(2), e13279.'
  mla: 'Martín‐Belmonte, Alejandro, et al. “Nanoarchitecture of CaV&#62;2.1 Channels
    and GABAB Receptors in the Mouse Hippocampus: Impact of APP/PS1 Pathology.” <i>Brain
    Pathology</i>, vol. 35, no. 2, e13279, Wiley, 2025, doi:<a href="https://doi.org/10.1111/bpa.13279">10.1111/bpa.13279</a>.'
  short: A. Martín‐Belmonte, C. Aguado, R. Alfaro‐Ruiz, A. Kulik, L. de la Ossa, A.E.
    Moreno‐Martínez, S. Alberquilla, L. García‐Carracedo, M. Fernández, A. Fajardo‐Serrano,
    E. Aso, R. Shigemoto, E.D. Martín, Y. Fukazawa, F. Ciruela, R. Luján, Brain Pathology
    35 (2025).
das_tickbox: '1'
dataavailabilitystatement: All data used and/or analyzed during the current study
  are available from the corresponding author on reasonable request.
date_created: 2024-07-22T07:48:20Z
date_published: 2025-03-01T00:00:00Z
date_updated: 2026-09-17T11:10:34Z
day: '01'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1111/bpa.13279
external_id:
  isi:
  - '001250034200001'
  pmid:
  - '38887180'
file:
- access_level: open_access
  checksum: 75a172800ab2e949abb66fba97cf70f0
  content_type: application/pdf
  creator: dernst
  date_created: 2025-04-16T09:56:08Z
  date_updated: 2025-04-16T09:56:08Z
  file_id: '19582'
  file_name: 2025_BrainPathology_MartinBelmonte.pdf
  file_size: 8767863
  relation: main_file
  success: 1
file_date_updated: 2025-04-16T09:56:08Z
fulldoi: https://doi.org/10.1111/bpa.13279
has_accepted_license: '1'
intvolume: '        35'
isi: 1
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Brain Pathology
publication_identifier:
  eissn:
  - 1750-3639
  issn:
  - 1015-6305
publication_status: published
publisher: Wiley
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: yes
title: 'Nanoarchitecture of CaV>2.1 channels and GABAB receptors in the mouse hippocampus:
  Impact of APP/PS1 pathology'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 35
year: '2025'
...
---
OA_place: publisher
_id: '20292'
abstract:
- lang: eng
  text: In automated decision-making, it is desirable that outputs of decision-makers
    be robust to slight perturbations in their inputs, a property that may be called
    input-output robustness. Input-output robustness appears in various different
    forms in the literature, such as robustness of AI models to adversarial or semantic
    perturbations and individual fairness of AI models that make decisions about humans.
    We propose runtime monitoring of input-output robustness of deployed, black-box
    AI models, where the goal is to design monitors that would observe one long execution
    sequence of the model, and would raise an alarm whenever it is detected that two
    similar inputs from the past led to dissimilar outputs. This way, monitoring will
    complement existing offline ''robustification'' approaches to increase the trustworthiness
    of AI decision-makers. We show that the monitoring problem can be cast as the
    fixed-radius nearest neighbor (FRNN) search problem, which, despite being well-studied,
    lacks suitable online solutions. We present our tool Clemont, which offers a number
    of lightweight monitors, some of which use upgraded online variants of existing
    FRNN algorithms, and one uses a novel algorithm based on binary decision diagrams--a
    data-structure commonly used in software and hardware verification. We have also
    developed an efficient parallelization technique that can substantially cut down
    the computation time of monitors for which the distance between input-output pairs
    is measured using the L∞norm. Using standard benchmarks from the literature of
    adversarial and semantic robustness and individual fairness, we perform a comparative
    study of different monitors in Clemont, and demonstrate their effectiveness in
    correctly detecting robustness violations at runtime.
acknowledgement: This work was supported in part by the ERC project ERC-2020-AdG 101020093
  and the SBI Foundation Hub for Data Science &Analytics, IIT Bombay.
article_processing_charge: No
arxiv: 1
author:
- first_name: Ashutosh
  full_name: Gupta, Ashutosh
  id: 335E5684-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Konstantin
  full_name: Kueffner, Konstantin
  id: 8121a2d0-dc85-11ea-9058-af578f3b4515
  last_name: Kueffner
  orcid: 0000-0001-8974-2542
- first_name: Kaushik
  full_name: Mallik, Kaushik
  id: 0834ff3c-6d72-11ec-94e0-b5b0a4fb8598
  last_name: Mallik
  orcid: 0000-0001-9864-7475
- first_name: David
  full_name: Pape, David
  last_name: Pape
citation:
  ama: 'Gupta A, Henzinger TA, Kueffner K, Mallik K, Pape D. Monitoring robustness
    and individual fairness. In: <i>Proceedings of the 31st ACM SIGKDD Conference
    on Knowledge Discovery and Data Mining</i>. Vol 2. Association for Computing Machinery;
    2025:790-801. doi:<a href="https://doi.org/10.1145/3711896.3737054">10.1145/3711896.3737054</a>'
  apa: 'Gupta, A., Henzinger, T. A., Kueffner, K., Mallik, K., &#38; Pape, D. (2025).
    Monitoring robustness and individual fairness. In <i>Proceedings of the 31st ACM
    SIGKDD Conference on Knowledge Discovery and Data Mining</i> (Vol. 2, pp. 790–801).
    Toronto, Canada: Association for Computing Machinery. <a href="https://doi.org/10.1145/3711896.3737054">https://doi.org/10.1145/3711896.3737054</a>'
  chicago: Gupta, Ashutosh, Thomas A Henzinger, Konstantin Kueffner, Kaushik Mallik,
    and David Pape. “Monitoring Robustness and Individual Fairness.” In <i>Proceedings
    of the 31st ACM SIGKDD Conference on Knowledge Discovery and Data Mining</i>,
    2:790–801. Association for Computing Machinery, 2025. <a href="https://doi.org/10.1145/3711896.3737054">https://doi.org/10.1145/3711896.3737054</a>.
  ieee: A. Gupta, T. A. Henzinger, K. Kueffner, K. Mallik, and D. Pape, “Monitoring
    robustness and individual fairness,” in <i>Proceedings of the 31st ACM SIGKDD
    Conference on Knowledge Discovery and Data Mining</i>, Toronto, Canada, 2025,
    vol. 2, pp. 790–801.
  ista: 'Gupta A, Henzinger TA, Kueffner K, Mallik K, Pape D. 2025. Monitoring robustness
    and individual fairness. Proceedings of the 31st ACM SIGKDD Conference on Knowledge
    Discovery and Data Mining. KDD: Conference on Knowledge Discovery and Data Mining
    vol. 2, 790–801.'
  mla: Gupta, Ashutosh, et al. “Monitoring Robustness and Individual Fairness.” <i>Proceedings
    of the 31st ACM SIGKDD Conference on Knowledge Discovery and Data Mining</i>,
    vol. 2, Association for Computing Machinery, 2025, pp. 790–801, doi:<a href="https://doi.org/10.1145/3711896.3737054">10.1145/3711896.3737054</a>.
  short: A. Gupta, T.A. Henzinger, K. Kueffner, K. Mallik, D. Pape, in:, Proceedings
    of the 31st ACM SIGKDD Conference on Knowledge Discovery and Data Mining, Association
    for Computing Machinery, 2025, pp. 790–801.
conference:
  end_date: 2025-08-07
  location: Toronto, Canada
  name: 'KDD: Conference on Knowledge Discovery and Data Mining'
  start_date: 2025-08-03
corr_author: '1'
date_created: 2025-09-07T22:01:33Z
date_published: 2025-08-03T00:00:00Z
date_updated: 2026-09-18T07:41:29Z
day: '03'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1145/3711896.3737054
ec_funded: 1
external_id:
  arxiv:
  - '2506.00496'
file:
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  creator: dernst
  date_created: 2025-09-08T08:46:31Z
  date_updated: 2025-09-08T08:46:31Z
  file_id: '20310'
  file_name: 2025_KDD_Gupta.pdf
  file_size: 7745940
  relation: main_file
  success: 1
file_date_updated: 2025-09-08T08:46:31Z
fulldoi: https://doi.org/10.1145/3711896.3737054
has_accepted_license: '1'
intvolume: '         2'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 790-801
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: Proceedings of the 31st ACM SIGKDD Conference on Knowledge Discovery
  and Data Mining
publication_identifier:
  isbn:
  - '9798400714542'
  issn:
  - 2154-817X
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/ariez-xyz/clemont
  record:
  - id: '22808'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Monitoring robustness and individual fairness
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '21090'
abstract:
- lang: eng
  text: Fairness in AI is traditionally studied as a static property evaluated once,
    over a fixed dataset. However, real-world AI systems operate sequentially, with
    outcomes and environments evolving over time. This paper proposes a framework
    for analysing fairness as a runtime property. Using a minimal yet expressive model
    based on sequences of coin tosses with possibly evolving biases, we study the
    problems of monitoring and enforcing fairness expressed in either toss outcomes
    or coin biases. Since there is no one-size-fits-all solution for either problem,
    we provide a summary of monitoring and enforcement strategies, parametrised by
    environment dynamics, prediction horizon, and confidence thresholds. For both
    problems, we present general results under simple or minimal assumptions. We survey
    existing solutions for the monitoring problem for Markovian and additive dynamics,
    and existing solutions for the enforcement problem in static settings with known
    dynamics.
acknowledgement: 'This work is supported by the European Research Council under Grant
  No.: ERC-2020-AdG 101020093.'
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Filip
  full_name: Cano Cordoba, Filip
  id: 708cad98-e86a-11ef-8098-bdae2d7c6af1
  last_name: Cano Cordoba
  orcid: 0000-0002-0783-904X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Konstantin
  full_name: Kueffner, Konstantin
  id: 8121a2d0-dc85-11ea-9058-af578f3b4515
  last_name: Kueffner
  orcid: 0000-0001-8974-2542
citation:
  ama: 'Cano Cordoba F, Henzinger TA, Kueffner K. Algorithmic fairness: A runtime
    perspective. In: <i>25th International Conference on Runtime Verification</i>.
    Vol 16087. Springer Nature; 2025:1-21. doi:<a href="https://doi.org/10.1007/978-3-032-05435-7_1">10.1007/978-3-032-05435-7_1</a>'
  apa: 'Cano Cordoba, F., Henzinger, T. A., &#38; Kueffner, K. (2025). Algorithmic
    fairness: A runtime perspective. In <i>25th International Conference on Runtime
    Verification</i> (Vol. 16087, pp. 1–21). Graz, Austria: Springer Nature. <a href="https://doi.org/10.1007/978-3-032-05435-7_1">https://doi.org/10.1007/978-3-032-05435-7_1</a>'
  chicago: 'Cano Cordoba, Filip, Thomas A Henzinger, and Konstantin Kueffner. “Algorithmic
    Fairness: A Runtime Perspective.” In <i>25th International Conference on Runtime
    Verification</i>, 16087:1–21. Springer Nature, 2025. <a href="https://doi.org/10.1007/978-3-032-05435-7_1">https://doi.org/10.1007/978-3-032-05435-7_1</a>.'
  ieee: 'F. Cano Cordoba, T. A. Henzinger, and K. Kueffner, “Algorithmic fairness:
    A runtime perspective,” in <i>25th International Conference on Runtime Verification</i>,
    Graz, Austria, 2025, vol. 16087, pp. 1–21.'
  ista: 'Cano Cordoba F, Henzinger TA, Kueffner K. 2025. Algorithmic fairness: A runtime
    perspective. 25th International Conference on Runtime Verification. RV: Runtime
    Verification, LNCS, vol. 16087, 1–21.'
  mla: 'Cano Cordoba, Filip, et al. “Algorithmic Fairness: A Runtime Perspective.”
    <i>25th International Conference on Runtime Verification</i>, vol. 16087, Springer
    Nature, 2025, pp. 1–21, doi:<a href="https://doi.org/10.1007/978-3-032-05435-7_1">10.1007/978-3-032-05435-7_1</a>.'
  short: F. Cano Cordoba, T.A. Henzinger, K. Kueffner, in:, 25th International Conference
    on Runtime Verification, Springer Nature, 2025, pp. 1–21.
conference:
  end_date: 2025-09-19
  location: Graz, Austria
  name: 'RV: Runtime Verification'
  start_date: 2025-09-15
corr_author: '1'
date_created: 2026-01-29T16:01:41Z
date_published: 2025-09-13T00:00:00Z
date_updated: 2026-09-18T07:41:29Z
day: '13'
department:
- _id: ToHe
doi: 10.1007/978-3-032-05435-7_1
ec_funded: 1
external_id:
  arxiv:
  - '2507.20711'
fulldoi: https://doi.org/10.1007/978-3-032-05435-7_1
intvolume: '     16087'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2507.20711
month: '09'
oa: 1
oa_version: Preprint
page: 1-21
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 25th International Conference on Runtime Verification
publication_identifier:
  eisbn:
  - '9783032054357'
  eissn:
  - 1611-3349
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
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  - id: '22808'
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    status: public
status: public
title: 'Algorithmic fairness: A runtime perspective'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16087
year: '2025'
...
---
APC_amount: 2754,32 EUR
OA_place: publisher
OA_type: hybrid
_id: '19627'
abstract:
- lang: eng
  text: Differentially private gradient descent (DP-GD) is a popular algorithm to
    train deep learning models with provable guarantees on the privacy of the training
    data. In the last decade, the problem of understanding its performance cost with
    respect to standard GD has received remarkable attention from the research community,
    which formally derived upper bounds on the excess population risk  RP  in different
    learning settings. However, existing bounds typically degrade with over-parameterization,
    i.e., as the number of parameters  p  gets larger than the number of training
    samples  n  -- a regime which is ubiquitous in current deep-learning practice.
    As a result, the lack of theoretical insights leaves practitioners without clear
    guidance, leading some to reduce the effective number of trainable parameters
    to improve performance, while others use larger models to achieve better results
    through scale. In this work, we show that in the popular random features model
    with quadratic loss, for any sufficiently large  p , privacy can be obtained for
    free, i.e.,  |RP|=o(1) , not only when the privacy parameter  ε  has constant
    order, but also in the strongly private setting  ε=o(1) . This challenges the
    common wisdom that over-parameterization inherently hinders performance in private
    learning.
acknowledgement: This research was funded in whole, or in part, by the Austrian Science
  Fund (FWF) Grant number COE 12. For the purpose of open access, the author has applied
  a CC BY public copyright license to any Author Accepted Manuscript version arising
  from this submission. The authors were also supported by the 2019 Lopez-Loreta prize,
  and Simone Bombari was supported by a Google PhD fellowship. We thank Diyuan Wu,
  Edwige Cyffers, Francesco Pedrotti, Inbar Seroussi, Nikita P. Kalinin, Pietro Pelliconi,
  Roodabeh Safavi, Yizhe Zhu, and Zhichao Wang for helpful discussions.
article_number: e2423072122
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Simone
  full_name: Bombari, Simone
  id: ca726dda-de17-11ea-bc14-f9da834f63aa
  last_name: Bombari
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
citation:
  ama: Bombari S, Mondelli M. Privacy for free in the overparameterized regime. <i>Proceedings
    of the National Academy of Sciences</i>. 2025;122(15). doi:<a href="https://doi.org/10.1073/pnas.2423072122">10.1073/pnas.2423072122</a>
  apa: Bombari, S., &#38; Mondelli, M. (2025). Privacy for free in the overparameterized
    regime. <i>Proceedings of the National Academy of Sciences</i>. National Academy
    of Sciences. <a href="https://doi.org/10.1073/pnas.2423072122">https://doi.org/10.1073/pnas.2423072122</a>
  chicago: Bombari, Simone, and Marco Mondelli. “Privacy for Free in the Overparameterized
    Regime.” <i>Proceedings of the National Academy of Sciences</i>. National Academy
    of Sciences, 2025. <a href="https://doi.org/10.1073/pnas.2423072122">https://doi.org/10.1073/pnas.2423072122</a>.
  ieee: S. Bombari and M. Mondelli, “Privacy for free in the overparameterized regime,”
    <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no. 15. National
    Academy of Sciences, 2025.
  ista: Bombari S, Mondelli M. 2025. Privacy for free in the overparameterized regime.
    Proceedings of the National Academy of Sciences. 122(15), e2423072122.
  mla: Bombari, Simone, and Marco Mondelli. “Privacy for Free in the Overparameterized
    Regime.” <i>Proceedings of the National Academy of Sciences</i>, vol. 122, no.
    15, e2423072122, National Academy of Sciences, 2025, doi:<a href="https://doi.org/10.1073/pnas.2423072122">10.1073/pnas.2423072122</a>.
  short: S. Bombari, M. Mondelli, Proceedings of the National Academy of Sciences
    122 (2025).
corr_author: '1'
date_created: 2025-04-27T22:02:13Z
date_published: 2025-04-15T00:00:00Z
date_updated: 2026-09-21T13:07:01Z
day: '15'
ddc:
- '000'
department:
- _id: MaMo
doi: 10.1073/pnas.2423072122
external_id:
  arxiv:
  - '2410.14787'
  isi:
  - '001471214000001'
  pmid:
  - '40215275'
file:
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  checksum: 1ac6f78e368d35a0cafb4d2d9bd63443
  content_type: application/pdf
  creator: dernst
  date_created: 2025-05-05T07:27:54Z
  date_updated: 2025-05-05T07:27:54Z
  file_id: '19648'
  file_name: 2025_PNAS_Bombari.pdf
  file_size: 2328320
  relation: main_file
  success: 1
file_date_updated: 2025-05-05T07:27:54Z
fulldoi: https://doi.org/10.1073/pnas.2423072122
has_accepted_license: '1'
intvolume: '       122'
isi: 1
issue: '15'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
  name: Prix Lopez-Loretta 2019 - Marco Mondelli
- _id: 92099302-16d5-11f0-9cad-f9a785f54fbd
  name: 'Trustworthy Deep Learning Theory: Private Over-Parameterized Models and Robust
    LLMs'
- _id: 74caaef7-b034-11f1-8f2d-e0e993bb422e
  grant_number: COE12
  name: Bilateral Artificial Intelligence (Mondelli)
publication: Proceedings of the National Academy of Sciences
publication_identifier:
  eissn:
  - 1091-6490
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  record:
  - id: '22857'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Privacy for free in the overparameterized regime
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 122
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '21324'
abstract:
- lang: eng
  text: Learning models have been shown to rely on spurious correlations between non-predictive
    features and the associated labels in the training data, with negative implications
    on robustness, bias and fairness. In this work, we provide a statistical characterization
    of this phenomenon for high-dimensional regression, when the data contains a predictive
    core feature x and a spurious feature y. Specifically, we quantify the amount
    of spurious correlations C learned via linear regression, in terms of the data
    covariance and the strength λ of the ridge regularization. As a consequence, we
    first capture the simplicity of y through the spectrum of its covariance, and
    its correlation with x through the Schur complement of the full data covariance.
    Next, we prove a trade-off between C and the in-distribution test loss L, by showing
    that the value of λ that minimizes L lies in an interval where C is increasing.
    Finally, we investigate the effects of over-parameterization via the random features
    model, by showing its equivalence to regularized linear regression. Our theoretical
    results are supported by numerical experiments on Gaussian, Color-MNIST, and CIFAR-10
    datasets.
acknowledgement: Marco Mondelli is funded by the European Union (ERC, INF2, project
  number 101161364). Views and opinions expressed are however those of the author(s)
  only and do not necessarily reflect those of the European Union or the European
  Research Council Executive Agency. Neither the European Union nor the granting authority
  can be held responsible for them. Simone Bombari is supported by a Google PhD fellowship.
  The authors would like to thank GuanWen Qiu for helpful discussions.
alternative_title:
- PMLR
article_processing_charge: No
arxiv: 1
author:
- first_name: Simone
  full_name: Bombari, Simone
  id: ca726dda-de17-11ea-bc14-f9da834f63aa
  last_name: Bombari
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
citation:
  ama: 'Bombari S, Mondelli M. Spurious correlations in high dimensional regression:
    The roles of regularization, simplicity bias and over-parameterization. In: <i>Proceedings
    of the 42nd International Conference on Machine Learning</i>. Vol 267. ML Research
    Press; 2025:4839-4873.'
  apa: 'Bombari, S., &#38; Mondelli, M. (2025). Spurious correlations in high dimensional
    regression: The roles of regularization, simplicity bias and over-parameterization.
    In <i>Proceedings of the 42nd International Conference on Machine Learning</i>
    (Vol. 267, pp. 4839–4873). Vancouver, Canada: ML Research Press.'
  chicago: 'Bombari, Simone, and Marco Mondelli. “Spurious Correlations in High Dimensional
    Regression: The Roles of Regularization, Simplicity Bias and over-Parameterization.”
    In <i>Proceedings of the 42nd International Conference on Machine Learning</i>,
    267:4839–73. ML Research Press, 2025.'
  ieee: 'S. Bombari and M. Mondelli, “Spurious correlations in high dimensional regression:
    The roles of regularization, simplicity bias and over-parameterization,” in <i>Proceedings
    of the 42nd International Conference on Machine Learning</i>, Vancouver, Canada,
    2025, vol. 267, pp. 4839–4873.'
  ista: 'Bombari S, Mondelli M. 2025. Spurious correlations in high dimensional regression:
    The roles of regularization, simplicity bias and over-parameterization. Proceedings
    of the 42nd International Conference on Machine Learning. ICML: International
    Conference on Machine Learning, PMLR, vol. 267, 4839–4873.'
  mla: 'Bombari, Simone, and Marco Mondelli. “Spurious Correlations in High Dimensional
    Regression: The Roles of Regularization, Simplicity Bias and over-Parameterization.”
    <i>Proceedings of the 42nd International Conference on Machine Learning</i>, vol.
    267, ML Research Press, 2025, pp. 4839–73.'
  short: S. Bombari, M. Mondelli, in:, Proceedings of the 42nd International Conference
    on Machine Learning, ML Research Press, 2025, pp. 4839–4873.
conference:
  end_date: 2025-07-19
  location: Vancouver, Canada
  name: 'ICML: International Conference on Machine Learning'
  start_date: 2025-07-13
corr_author: '1'
date_created: 2026-02-18T11:58:00Z
date_published: 2025-07-30T00:00:00Z
date_updated: 2026-09-21T13:07:01Z
day: '30'
ddc:
- '000'
department:
- _id: MaMo
external_id:
  arxiv:
  - '2502.01347'
file:
- access_level: open_access
  checksum: d4ba4f7717b362ca38878f45e57bd643
  content_type: application/pdf
  creator: dernst
  date_created: 2026-02-19T08:04:38Z
  date_updated: 2026-02-19T08:04:38Z
  file_id: '21335'
  file_name: 2025_ICML_Bombari.pdf
  file_size: 887526
  relation: main_file
  success: 1
file_date_updated: 2026-02-19T08:04:38Z
has_accepted_license: '1'
intvolume: '       267'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 4839-4873
project:
- _id: 911e6d1f-16d5-11f0-9cad-c5c68c6a1cdf
  grant_number: '101161364'
  name: 'Inference in High Dimensions: Light-speed Algorithms and Information Limits'
- _id: 92099302-16d5-11f0-9cad-f9a785f54fbd
  name: 'Trustworthy Deep Learning Theory: Private Over-Parameterized Models and Robust
    LLMs'
publication: Proceedings of the 42nd International Conference on Machine Learning
publication_identifier:
  eissn:
  - 2640-3498
publication_status: published
publisher: ML Research Press
quality_controlled: '1'
related_material:
  record:
  - id: '22857'
    relation: dissertation_contains
    status: public
status: public
title: 'Spurious correlations in high dimensional regression: The roles of regularization,
  simplicity bias and over-parameterization'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 267
year: '2025'
...
---
APC_amount: 1395,61 EUR
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20370'
abstract:
- lang: eng
  text: The Huntingtin protein (HTT), named for its role in Huntington’s disease,
    has been best understood as a scaffolding protein that promotes vesicle transport
    by molecular motors along microtubules. Here, we show that HTT also interacts
    with the actin cytoskeleton, and its loss of function disturbs the morphology
    and function of the axonal growth cone. We demonstrate that HTT organizes F-actin
    into bundles. Cryo–electron tomography (cryo-ET) and subtomogram averaging (STA)
    structural analyses reveal that HTT’s N-terminal HEAT and Bridge domains wrap
    around F-actin, while the C-terminal HEAT domain is displaced; furthermore, HTT
    dimerizes via the N-HEAT domain to bridge parallel actin filaments separated by
    ~20 nanometers. Our study provides the structural basis for understanding how
    HTT interacts with and organizes the actin cytoskeleton.
acknowledgement: 'We thank C. Cuveillier, J. Delaroche, T. Ferraro, and A. Zanchi
  for help with TIRF experiments, electron microscopy preparation, data analysis,
  and cell cultures, respectively; A. Antkowiak, C. Bosc, C. Fassier, A. Fourest-Lieuvin,
  and V. Brandt for helpful discussions. We acknowledge the contribution of the Photonic
  Imaging Center of Grenoble Institute Neuroscience which is part of the ISdV core
  facility and certified by the IBiSA label and ICM.Quant (RRID:SCR_026393) core facility
  of the Paris Brain Institute (ICM); the AniRA lentivector production facility from
  the CELPHEDIA Infrastructure and SFR Biosciences (UAR3444/CNRS, US8/Inserm, ENS
  de Lyon, UCBL); the Scientific Service Units (SSUs) of ISTA through resources provided
  by Scientific Computing (SciComp, A. Schloegl and S. Elefante); and the Electron
  Microscopy Facility (EMF, V.V. Hodirnau). The software programs used for the processing
  were supported by SBGrid (www.sbgrid.org). This work was supported by the Agence
  Nationale pour la Recherche (AXYON: ANR-18-CE16-0009-01, S.H.), Austrian Science
  Fund (FWF) grants (P33367, F.K.M.S.; E435, J.M.H.), ChanZuckerberg Initiative (CZI)
  grant (DAF2021-234754, F.K.M.S.), Hereditary Disease Foundation Research Grant (HDF
  990846, M.C.), European Union (ERC: ActinID 101076260, F.K.M.S.), Fondation pour
  la Recherche Médicale (FRM: équipe labellisée DEQ202203014675, S.H.; PhD fellowship,
  FDT202001010865, R.C.), Korea Health Industry Development Institute (KHIDI) (Korea-Switzerland
  global research support grant: RS-2023-00266300, J.-J.S.), National Research Foundation
  (NRF) of Korea (Korea-Austria collaborative grant NRF-2019K1A3A1A181160, J.-J.S.
  and F.K.M.S.; NRF-2020R1A2B5B03001517 and RS-2024-00333346 and RS-2024-00436173,
  J.-J.S.; 2021R1C1C1006700, D.K.).'
article_number: eadw4124
article_processing_charge: Yes
article_type: original
author:
- first_name: Rémi
  full_name: Carpentier, Rémi
  last_name: Carpentier
- first_name: Jaesung
  full_name: Kim, Jaesung
  last_name: Kim
- first_name: Mariacristina
  full_name: Capizzi, Mariacristina
  last_name: Capizzi
- first_name: Hyeongju
  full_name: Kim, Hyeongju
  last_name: Kim
- first_name: Florian
  full_name: Fäßler, Florian
  id: 404F5528-F248-11E8-B48F-1D18A9856A87
  last_name: Fäßler
  orcid: 0000-0001-7149-769X
- first_name: Jesse
  full_name: Hansen, Jesse
  id: 1063c618-6f9b-11ec-9123-f912fccded63
  last_name: Hansen
  orcid: 0000-0001-7967-2085
- first_name: Min Jeong
  full_name: Kim, Min Jeong
  last_name: Kim
- first_name: Eric
  full_name: Denarier, Eric
  last_name: Denarier
- first_name: Béatrice
  full_name: Blot, Béatrice
  last_name: Blot
- first_name: Marine
  full_name: Degennaro, Marine
  last_name: Degennaro
- first_name: Sophia
  full_name: Labou, Sophia
  last_name: Labou
- first_name: Isabelle
  full_name: Arnal, Isabelle
  last_name: Arnal
- first_name: Maria J.
  full_name: Marcaida, Maria J.
  last_name: Marcaida
- first_name: Matteo Dal
  full_name: Peraro, Matteo Dal
  last_name: Peraro
- first_name: Doory
  full_name: Kim, Doory
  last_name: Kim
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Ji-Joon
  full_name: Song, Ji-Joon
  last_name: Song
- first_name: Sandrine
  full_name: Humbert, Sandrine
  last_name: Humbert
citation:
  ama: Carpentier R, Kim J, Capizzi M, et al. Structure of the Huntingtin F-actin
    complex reveals its role in cytoskeleton organization. <i>Science Advances</i>.
    2025;11(38). doi:<a href="https://doi.org/10.1126/sciadv.adw4124">10.1126/sciadv.adw4124</a>
  apa: Carpentier, R., Kim, J., Capizzi, M., Kim, H., Fäßler, F., Hansen, J., … Humbert,
    S. (2025). Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton
    organization. <i>Science Advances</i>. AAAS. <a href="https://doi.org/10.1126/sciadv.adw4124">https://doi.org/10.1126/sciadv.adw4124</a>
  chicago: Carpentier, Rémi, Jaesung Kim, Mariacristina Capizzi, Hyeongju Kim, Florian
    Fäßler, Jesse Hansen, Min Jeong Kim, et al. “Structure of the Huntingtin F-Actin
    Complex Reveals Its Role in Cytoskeleton Organization.” <i>Science Advances</i>.
    AAAS, 2025. <a href="https://doi.org/10.1126/sciadv.adw4124">https://doi.org/10.1126/sciadv.adw4124</a>.
  ieee: R. Carpentier <i>et al.</i>, “Structure of the Huntingtin F-actin complex
    reveals its role in cytoskeleton organization,” <i>Science Advances</i>, vol.
    11, no. 38. AAAS, 2025.
  ista: Carpentier R, Kim J, Capizzi M, Kim H, Fäßler F, Hansen J, Kim MJ, Denarier
    E, Blot B, Degennaro M, Labou S, Arnal I, Marcaida MJ, Peraro MD, Kim D, Schur
    FK, Song J-J, Humbert S. 2025. Structure of the Huntingtin F-actin complex reveals
    its role in cytoskeleton organization. Science Advances. 11(38), eadw4124.
  mla: Carpentier, Rémi, et al. “Structure of the Huntingtin F-Actin Complex Reveals
    Its Role in Cytoskeleton Organization.” <i>Science Advances</i>, vol. 11, no.
    38, eadw4124, AAAS, 2025, doi:<a href="https://doi.org/10.1126/sciadv.adw4124">10.1126/sciadv.adw4124</a>.
  short: R. Carpentier, J. Kim, M. Capizzi, H. Kim, F. Fäßler, J. Hansen, M.J. Kim,
    E. Denarier, B. Blot, M. Degennaro, S. Labou, I. Arnal, M.J. Marcaida, M.D. Peraro,
    D. Kim, F.K. Schur, J.-J. Song, S. Humbert, Science Advances 11 (2025).
corr_author: '1'
date_created: 2025-09-22T08:00:52Z
date_published: 2025-09-19T00:00:00Z
date_updated: 2026-09-24T08:17:37Z
day: '19'
ddc:
- '570'
department:
- _id: FlSc
doi: 10.1126/sciadv.adw4124
external_id:
  isi:
  - '001575751700013'
  pmid:
  - '40971423'
file:
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  checksum: 4e2407bdabf8d53f399eb8a20d86218e
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  date_created: 2025-09-23T07:57:51Z
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  file_id: '20372'
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  file_size: 3599137
  relation: main_file
  success: 1
file_date_updated: 2025-09-23T07:57:51Z
fulldoi: https://doi.org/10.1126/sciadv.adw4124
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: '38'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 9B954C5C-BA93-11EA-9121-9846C619BF3A
  grant_number: P33367
  name: Structure and isoform diversity of the Arp2/3 complex
- _id: 7bd318a1-9f16-11ee-852c-cc9217763180
  grant_number: E435
  name: In Situ Actin Structures via Hybrid Cryo-electron Microscopy
- _id: 62909c6f-2b32-11ec-9570-e1476aab5308
  grant_number: CZI01
  name: CryoMinflux-guided in-situ molecular census and structure determination
- _id: bd980d18-d553-11ed-ba76-ceaa645c97eb
  grant_number: '101076260'
  name: A molecular atlas of Actin filament IDentities in the cell motility machinery
- _id: 3AC91DDA-15DF-11EA-824D-93A3E7B544D1
  call_identifier: FWF
  name: FWF Open Access Fund
publication: Science Advances
publication_identifier:
  eissn:
  - 2375-2548
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure of the Huntingtin F-actin complex reveals its role in cytoskeleton
  organization
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20324'
abstract:
- lang: eng
  text: We report relaxation oscillations in a one-dimensional array of Josephson
    junctions, wherein the array dynamically switches between low-current and high-current
    states. The oscillations are current-voltage dual to those ordinarily observed
    in single junctions. The current-voltage dual circuit quantitatively accounts
    for temporal dynamics of the array, including the dependence on biasing conditions.
    Injection locking of the oscillations results in well-developed current plateaux.
    A thermal model explains the self-consistent reduction of the superconducting
    gap due to overheating of the array in the high-current state. Our work suggests
    that overheating determines the switching from the high-current state to the low-current
    state.
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
acknowledgement: We gratefully acknowledge support from the Miba Machine Shop and
  the Nanofabrictation Facility at IST Austria. This work was supported by the Austrian
  FWF under Grant No. P33692-N (S.M., J.S., and A.P.H.), the European Union’s Horizon
  2020 research and innovation program under Marie Skłodowska-Curie Grant Agreement
  No. 754411 (J.S.), and a NOMIS Foundation research grant (A.P.H.).
article_number: '014035'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Soham
  full_name: Mukhopadhyay, Soham
  id: FDE60288-A89D-11E9-947F-1AF6E5697425
  last_name: Mukhopadhyay
  orcid: 0000-0001-5263-5559
- first_name: Diego A
  full_name: Lancheros Naranjo, Diego A
  id: 6c55e976-15b2-11ec-abd3-d790e8937fde
  last_name: Lancheros Naranjo
- first_name: Jorden L
  full_name: Senior, Jorden L
  id: 5479D234-2D30-11EA-89CC-40953DDC885E
  last_name: Senior
  orcid: 0000-0002-0672-9295
- first_name: Andrew P
  full_name: Higginbotham, Andrew P
  id: 4AD6785A-F248-11E8-B48F-1D18A9856A87
  last_name: Higginbotham
  orcid: 0000-0003-2607-2363
citation:
  ama: Mukhopadhyay S, Lancheros Naranjo DA, Senior JL, Higginbotham AP. Dual relaxation
    oscillations in a Josephson-junction array. <i>Physical Review Applied</i>. 2025;24.
    doi:<a href="https://doi.org/10.1103/qvls-7s3q">10.1103/qvls-7s3q</a>
  apa: Mukhopadhyay, S., Lancheros Naranjo, D. A., Senior, J. L., &#38; Higginbotham,
    A. P. (2025). Dual relaxation oscillations in a Josephson-junction array. <i>Physical
    Review Applied</i>. American Physical Society. <a href="https://doi.org/10.1103/qvls-7s3q">https://doi.org/10.1103/qvls-7s3q</a>
  chicago: Mukhopadhyay, Soham, Diego A Lancheros Naranjo, Jorden L Senior, and Andrew
    P Higginbotham. “Dual Relaxation Oscillations in a Josephson-Junction Array.”
    <i>Physical Review Applied</i>. American Physical Society, 2025. <a href="https://doi.org/10.1103/qvls-7s3q">https://doi.org/10.1103/qvls-7s3q</a>.
  ieee: S. Mukhopadhyay, D. A. Lancheros Naranjo, J. L. Senior, and A. P. Higginbotham,
    “Dual relaxation oscillations in a Josephson-junction array,” <i>Physical Review
    Applied</i>, vol. 24. American Physical Society, 2025.
  ista: Mukhopadhyay S, Lancheros Naranjo DA, Senior JL, Higginbotham AP. 2025. Dual
    relaxation oscillations in a Josephson-junction array. Physical Review Applied.
    24, 014035.
  mla: Mukhopadhyay, Soham, et al. “Dual Relaxation Oscillations in a Josephson-Junction
    Array.” <i>Physical Review Applied</i>, vol. 24, 014035, American Physical Society,
    2025, doi:<a href="https://doi.org/10.1103/qvls-7s3q">10.1103/qvls-7s3q</a>.
  short: S. Mukhopadhyay, D.A. Lancheros Naranjo, J.L. Senior, A.P. Higginbotham,
    Physical Review Applied 24 (2025).
corr_author: '1'
date_created: 2025-09-10T05:41:30Z
date_published: 2025-07-17T00:00:00Z
date_updated: 2026-09-24T10:13:38Z
day: '17'
ddc:
- '530'
department:
- _id: GradSch
- _id: AnHi
doi: 10.1103/qvls-7s3q
ec_funded: 1
external_id:
  arxiv:
  - '2408.07829 '
  isi:
  - '001537333100001'
file:
- access_level: open_access
  checksum: 6cc3c9beeb7c0a88ee0a072c9a32b78b
  content_type: application/pdf
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  date_created: 2025-09-10T07:29:06Z
  date_updated: 2025-09-10T07:29:06Z
  file_id: '20335'
  file_name: 2025_PhysReviewAppl_Mukhopadhyay.pdf
  file_size: 1370466
  relation: main_file
  success: 1
file_date_updated: 2025-09-10T07:29:06Z
fulldoi: https://doi.org/10.1103/qvls-7s3q
has_accepted_license: '1'
intvolume: '        24'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 0aa3608a-070f-11eb-9043-e9cd8a2bd931
  grant_number: P33692
  name: Cavity electromechanics across a quantum phase transition
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: eb9b30ac-77a9-11ec-83b8-871f581d53d2
  name: Protected states of quantum matter
publication: Physical Review Applied
publication_identifier:
  issn:
  - 2331-7019
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '18057'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Dual relaxation oscillations in a Josephson-junction array
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2025'
...
---
OA_place: publisher
OA_type: gold
_id: '19370'
abstract:
- lang: eng
  text: Sex-linked and autosomal loci experience different selective pressures and
    evolutionary dynamics. X (or Z) chromosomes are often hemizygous in males (or
    females), as Y (or W) chromosomes often degenerate. Such hemizygous regions can
    be under greater efficacy of selection, as recessive mutations are immediately
    exposed to selection in the heterogametic sex leading to faster adaptation and
    faster divergence on the X chromosome (the so-called Faster-X or Faster-Z effect).
    However, in young nonrecombining regions, Y/W chromosomes often have many functional
    genes, and many X/Z-linked loci are therefore diploid. The sheltering of recessive
    mutations on the X/Z by the Y/W homolog is expected to drive slower adaptation
    for diploid X/Z loci, i.e. a reduction in the efficacy of selection. While the
    Faster-X effect has been studied extensively, much less is known empirically about
    the evolutionary dynamics of diploid X or Z chromosomes. Here, we took advantage
    of published population genomic data in the female-heterogametic human parasite
    Schistosoma japonicum to characterize the gene content and diversity levels of
    the diploid and hemizygous regions of the Z chromosome. We used different metrics
    of selective pressures acting on genes to test for differences in the efficacy
    of selection in hemizygous and diploid Z regions, relative to autosomes. We found
    consistent patterns suggesting reduced Ne, and reduced efficacy of purifying selection,
    on both hemizygous and diploid Z regions. Moreover, relaxed selection was particularly
    pronounced for female-biased genes on the diploid Z, as predicted by recent theoretical
    work.
acknowledgement: The authors would like to thank three anonymous reviewers for comments
  and suggestions. We are also grateful to Christelle Fraïsse, Marwan Elkrewi, and
  Filip Ruzicka for the help in this project.
article_number: evaf021
article_processing_charge: Yes
article_type: original
author:
- first_name: Andrea
  full_name: Mrnjavac, Andrea
  id: 353FAC84-AE61-11E9-8BFC-00D3E5697425
  last_name: Mrnjavac
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Mrnjavac A, Vicoso B. Reduced efficacy of selection on a young Z chromosome
    region of schistosoma japonicum. <i>Genome Biology and Evolution</i>. 2025;17(2).
    doi:<a href="https://doi.org/10.1093/gbe/evaf021">10.1093/gbe/evaf021</a>
  apa: Mrnjavac, A., &#38; Vicoso, B. (2025). Reduced efficacy of selection on a young
    Z chromosome region of schistosoma japonicum. <i>Genome Biology and Evolution</i>.
    Oxford University Press. <a href="https://doi.org/10.1093/gbe/evaf021">https://doi.org/10.1093/gbe/evaf021</a>
  chicago: Mrnjavac, Andrea, and Beatriz Vicoso. “Reduced Efficacy of Selection on
    a Young Z Chromosome Region of Schistosoma Japonicum.” <i>Genome Biology and Evolution</i>.
    Oxford University Press, 2025. <a href="https://doi.org/10.1093/gbe/evaf021">https://doi.org/10.1093/gbe/evaf021</a>.
  ieee: A. Mrnjavac and B. Vicoso, “Reduced efficacy of selection on a young Z chromosome
    region of schistosoma japonicum,” <i>Genome Biology and Evolution</i>, vol. 17,
    no. 2. Oxford University Press, 2025.
  ista: Mrnjavac A, Vicoso B. 2025. Reduced efficacy of selection on a young Z chromosome
    region of schistosoma japonicum. Genome Biology and Evolution. 17(2), evaf021.
  mla: Mrnjavac, Andrea, and Beatriz Vicoso. “Reduced Efficacy of Selection on a Young
    Z Chromosome Region of Schistosoma Japonicum.” <i>Genome Biology and Evolution</i>,
    vol. 17, no. 2, evaf021, Oxford University Press, 2025, doi:<a href="https://doi.org/10.1093/gbe/evaf021">10.1093/gbe/evaf021</a>.
  short: A. Mrnjavac, B. Vicoso, Genome Biology and Evolution 17 (2025).
corr_author: '1'
date_created: 2025-03-09T23:01:27Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2026-09-24T11:18:17Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evaf021
external_id:
  isi:
  - '001423671400001'
  pmid:
  - '39913672'
file:
- access_level: open_access
  checksum: e3aa993e3d6dad10cb806c243fa57408
  content_type: application/pdf
  creator: dernst
  date_created: 2025-03-10T08:25:59Z
  date_updated: 2025-03-10T08:25:59Z
  file_id: '19378'
  file_name: 2025_GBE_Mrnjavac.pdf
  file_size: 768371
  relation: main_file
  success: 1
file_date_updated: 2025-03-10T08:25:59Z
fulldoi: https://doi.org/10.1093/gbe/evaf021
has_accepted_license: '1'
intvolume: '        17'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genome Biology and Evolution
publication_identifier:
  eissn:
  - 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://git.ista.ac.at/amrnjava/schistosomes_slower_z
  record:
  - id: '18549'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Reduced efficacy of selection on a young Z chromosome region of schistosoma
  japonicum
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 17
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
_id: '18866'
abstract:
- lang: eng
  text: Using JWST Near Infrared Camera (NIRCam) images of the globular cluster 47,Tucanæ,
    (or NGC,104), taken at two epochs just 7 months apart, we derived proper-motion
    membership down to F322W2 ∼ 27. We identified an intriguing feature at the very
    low-mass end of the main sequence, around ∼ 0.08,M_⋅, at magnitudes F322W2 ∼ 24
    and m_ F150W2 ∼ 25. This feature, dubbed 'kink', is characterized by a prominent
    discontinuity in the slope of the main sequence. A similar discontinuity is seen
    in theoretical isochrones with oxygen-poor chemistries, related to the rapid onset
    of absorption. We therefore hypothesize that the cluster hosts disproportionately
    more oxygen-poor stars near the bottom of the main sequence compared to the upper
    main sequence and the red giant branch. Our results show no strong or conclusive
    evidence of a rise in the brown dwarf luminosity function at faint magnitudes,
    in contrast to previous findings likely affected by faint red background galaxies.
    In our analysis, we accounted for this contamination by using proper motion membership.
acknowledgement: We dedicate this paper to the memory of our colleague Prof. Harvey
  Richer (⋆ April 1944 —† 13 November 2023), a highly accomplished astronomer and
  expert in stellar populations and in particular within globular clusters, who passed
  away during this project. Harvey grew up in Montreal and was at least the second
  star man to graduate from his high school, having been preceded by William Shatner
  by more than a decade. He worked at the University of British Columbia for most
  of his career, and his focus was the late stages of stellar evolution, in particular
  carbon stars and white dwarfs. We thank the referee for his valuable suggestions
  and comments, which helped improve the paper, as well as for his prompt revision.
article_number: A68
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: M.
  full_name: Scalco, M.
  last_name: Scalco
- first_name: R.
  full_name: Gerasimov, R.
  last_name: Gerasimov
- first_name: L. R.
  full_name: Bedin, L. R.
  last_name: Bedin
- first_name: E.
  full_name: Vesperini, E.
  last_name: Vesperini
- first_name: M.
  full_name: Correnti, M.
  last_name: Correnti
- first_name: D.
  full_name: Nardiello, D.
  last_name: Nardiello
- first_name: A.
  full_name: Burgasser, A.
  last_name: Burgasser
- first_name: H.
  full_name: Richer, H.
  last_name: Richer
- first_name: Ilaria
  full_name: Caiazzo, Ilaria
  id: 8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d
  last_name: Caiazzo
  orcid: 0000-0002-4770-5388
- first_name: J.
  full_name: Heyl, J.
  last_name: Heyl
- first_name: M.
  full_name: Libralato, M.
  last_name: Libralato
- first_name: J.
  full_name: Anderson, J.
  last_name: Anderson
- first_name: M.
  full_name: Griggio, M.
  last_name: Griggio
citation:
  ama: Scalco M, Gerasimov R, Bedin LR, et al. JWST photometry and astrometry of 47
    Tucanæ. Discontinuity in the stellar sequence at the star--brown dwarf transition.
    <i>Astronomy &#38; Astrophysics</i>. 2025;694. doi:<a href="https://doi.org/10.1051/0004-6361/202452907">10.1051/0004-6361/202452907</a>
  apa: Scalco, M., Gerasimov, R., Bedin, L. R., Vesperini, E., Correnti, M., Nardiello,
    D., … Griggio, M. (2025). JWST photometry and astrometry of 47 Tucanæ. Discontinuity
    in the stellar sequence at the star--brown dwarf transition. <i>Astronomy &#38;
    Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202452907">https://doi.org/10.1051/0004-6361/202452907</a>
  chicago: Scalco, M., R. Gerasimov, L. R. Bedin, E. Vesperini, M. Correnti, D. Nardiello,
    A. Burgasser, et al. “JWST Photometry and Astrometry of 47 Tucanæ. Discontinuity
    in the Stellar Sequence at the Star--Brown Dwarf Transition.” <i>Astronomy &#38;
    Astrophysics</i>. EDP Sciences, 2025. <a href="https://doi.org/10.1051/0004-6361/202452907">https://doi.org/10.1051/0004-6361/202452907</a>.
  ieee: M. Scalco <i>et al.</i>, “JWST photometry and astrometry of 47 Tucanæ. Discontinuity
    in the stellar sequence at the star--brown dwarf transition,” <i>Astronomy &#38;
    Astrophysics</i>, vol. 694. EDP Sciences, 2025.
  ista: Scalco M, Gerasimov R, Bedin LR, Vesperini E, Correnti M, Nardiello D, Burgasser
    A, Richer H, Caiazzo I, Heyl J, Libralato M, Anderson J, Griggio M. 2025. JWST
    photometry and astrometry of 47 Tucanæ. Discontinuity in the stellar sequence
    at the star--brown dwarf transition. Astronomy &#38; Astrophysics. 694, A68.
  mla: Scalco, M., et al. “JWST Photometry and Astrometry of 47 Tucanæ. Discontinuity
    in the Stellar Sequence at the Star--Brown Dwarf Transition.” <i>Astronomy &#38;
    Astrophysics</i>, vol. 694, A68, EDP Sciences, 2025, doi:<a href="https://doi.org/10.1051/0004-6361/202452907">10.1051/0004-6361/202452907</a>.
  short: M. Scalco, R. Gerasimov, L.R. Bedin, E. Vesperini, M. Correnti, D. Nardiello,
    A. Burgasser, H. Richer, I. Caiazzo, J. Heyl, M. Libralato, J. Anderson, M. Griggio,
    Astronomy &#38; Astrophysics 694 (2025).
date_created: 2025-01-21T15:29:36Z
date_published: 2025-02-04T00:00:00Z
date_updated: 2026-09-24T13:45:58Z
day: '04'
ddc:
- '520'
department:
- _id: IlCa
doi: 10.1051/0004-6361/202452907
external_id:
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  - '2501.04446'
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fulldoi: https://doi.org/10.1051/0004-6361/202452907
has_accepted_license: '1'
intvolume: '       694'
isi: 1
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: JWST photometry and astrometry of 47 Tucanæ. Discontinuity in the stellar sequence
  at the star--brown dwarf transition
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 694
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18936'
abstract:
- lang: eng
  text: A major obstacle to predictive understanding of evolution stems from the complexity
    of biological systems, which prevents detailed characterization of key evolutionary
    properties. Here, we highlight some of the major sources of complexity that arise
    when relating molecular mechanisms to their evolutionary consequences and ask
    whether accounting for every mechanistic detail is important to accurately predict
    evolutionary outcomes. To do this, we developed a mechanistic model of a bacterial
    promoter regulated by 2 proteins, allowing us to connect any promoter genotype
    to 6 phenotypes that capture the dynamics of gene expression following an environmental
    switch. Accounting for the mechanisms that govern how this system works enabled
    us to provide an in-depth picture of how regulated bacterial promoters might evolve.
    More importantly, we used the model to explore which factors that contribute to
    the complexity of this system are essential for understanding its evolution, and
    which can be simplified without information loss. We found that several key evolutionary
    properties—the distribution of phenotypic and fitness effects of mutations, the
    evolutionary trajectories during selection for regulation—can be accurately captured
    without accounting for all, or even most, parameters of the system. Our findings
    point to the need for a mechanistic approach to studying evolution, as it enables
    tackling biological complexity and in doing so improves the ability to predict
    evolutionary outcomes.
acknowledgement: "The authors thank Nick Barton, Stepan Denisov, Claudia Igler, Srdjan
  Sarikas, Anna Staron, and the anonymous reviewers for useful comments and discussions
  that helped improve our work.\r\nFunding for this work was provided by the Wellcome
  Trust–Royal Society Sir Henry Dale Fellowship (216779/Z/19/Z) and the Royal Society
  Research Grant (RG\\R2\\232522) to M.L."
article_number: iyae191
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Mato
  full_name: Lagator, Mato
  id: 345D25EC-F248-11E8-B48F-1D18A9856A87
  last_name: Lagator
citation:
  ama: 'Grah R, Guet CC, Tkačik G, Lagator M. Linking molecular mechanisms to their
    evolutionary consequences: a primer. <i>Genetics</i>. 2025;229(2). doi:<a href="https://doi.org/10.1093/genetics/iyae191">10.1093/genetics/iyae191</a>'
  apa: 'Grah, R., Guet, C. C., Tkačik, G., &#38; Lagator, M. (2025). Linking molecular
    mechanisms to their evolutionary consequences: a primer. <i>Genetics</i>. Oxford
    University Press. <a href="https://doi.org/10.1093/genetics/iyae191">https://doi.org/10.1093/genetics/iyae191</a>'
  chicago: 'Grah, Rok, Calin C Guet, Gašper Tkačik, and Mato Lagator. “Linking Molecular
    Mechanisms to Their Evolutionary Consequences: A Primer.” <i>Genetics</i>. Oxford
    University Press, 2025. <a href="https://doi.org/10.1093/genetics/iyae191">https://doi.org/10.1093/genetics/iyae191</a>.'
  ieee: 'R. Grah, C. C. Guet, G. Tkačik, and M. Lagator, “Linking molecular mechanisms
    to their evolutionary consequences: a primer,” <i>Genetics</i>, vol. 229, no.
    2. Oxford University Press, 2025.'
  ista: 'Grah R, Guet CC, Tkačik G, Lagator M. 2025. Linking molecular mechanisms
    to their evolutionary consequences: a primer. Genetics. 229(2), iyae191.'
  mla: 'Grah, Rok, et al. “Linking Molecular Mechanisms to Their Evolutionary Consequences:
    A Primer.” <i>Genetics</i>, vol. 229, no. 2, iyae191, Oxford University Press,
    2025, doi:<a href="https://doi.org/10.1093/genetics/iyae191">10.1093/genetics/iyae191</a>.'
  short: R. Grah, C.C. Guet, G. Tkačik, M. Lagator, Genetics 229 (2025).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: Strains and plasmids are available upon request. All experimental
  raw data can be found in Supplementary Data 1. All code underpinning this work is
  available at https://github.com/Lagator-Group/Linking-Molecular-Mechanisms-to-their-Evolutionary-consequence-a-primer
  or upon request.  Supplemental material available at GENETICS online
date_created: 2025-01-29T08:21:35Z
date_published: 2025-02-01T00:00:00Z
date_updated: 2026-10-01T08:30:12Z
day: '01'
ddc:
- '570'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1093/genetics/iyae191
external_id:
  isi:
  - '001379194200001'
  pmid:
  - '39601269'
file:
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  date_created: 2025-04-16T09:41:04Z
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file_date_updated: 2025-04-16T09:41:04Z
fulldoi: https://doi.org/10.1093/genetics/iyae191
has_accepted_license: '1'
intvolume: '       229'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
publication: Genetics
publication_identifier:
  eissn:
  - 1943-2631
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: yes
title: 'Linking molecular mechanisms to their evolutionary consequences: a primer'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 229
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
_id: '18605'
abstract:
- lang: eng
  text: The response of clouds and moist-convective processes to heat loss to space
    by long-wave radiative cooling is an important feedback in the Earth's atmosphere.
    It is known that moist convection increases roughly in equilibrium with radiative
    cooling, an assumption often made in simplified models of the tropical atmosphere.
    In this study, we use an idealised two-dimensional model of the atmosphere introduced
    by Vallis et. al. and incorporate a bulk-cooling term, which is an idealisation
    of radiative cooling in the atmosphere. We comment briefly on the static stability
    of the system to dry and moist convection and characteris its moist convective
    response to changes in the bulk cooling. We find that, while the clear-sky regions
    of the model respond directly to the change in the cooling term, the regions dominated
    by moist convective plumes are insensitive to changes in cooling. Similar to previous
    findings from cloud-resolving models, we too find in our idealised setting that
    the majority of the increase in convection occurs via an increase in the areal
    coverage of convection, rather than its intensity. We argue that these small-scale
    convective processes are an upper bound on how quickly convective intensity can
    change to stay in equilibrium with radiative cooling.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The authors gratefully acknowledge the help of Julian Renaud and
  Alzbeta “Bety” Pechacova. Julian went through the relevant literature on the topic
  in the initial stages of the study in a very thorough manner and allowed the authors
  to understand the various types of idealised models that have been studied and the
  various approaches used. Bety ran simulations and performed analysis of the outputs
  of several simulations, which were crucial to bringing the article to its final
  form.\r\n\r\nThe authors also acknowledge the input of Prof. Martin Singh (Monash
  University, Australia) and discussions with Gregory Dritschel, Prof. Steven Tobias,
  and Prof. Douglas Parker (Leeds University, United Kingdom).\r\n\r\nThis project
  has received funding from the European Union's Horizon 2020 research and innovation
  programme under the Marie Sklodowska-Curie grant agreement No. 101034413. C. Muller
  gratefully acknowledges funding from the European Research Council (ERC) under the
  European Union's Horizon 2020 research and innovation program (Project CLUSTER,
  Grant Agreement No. 805041). This research was supported by the Scientific Service
  Units (SSU) of IST Austria through resources provided by Scientific Computing (SciComp)."
article_number: e4902
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Lokahith N
  full_name: Agasthya, Lokahith N
  id: cd100965-0804-11ed-9c55-f4878ff4e877
  last_name: Agasthya
- first_name: Caroline J
  full_name: Muller, Caroline J
  id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b
  last_name: Muller
  orcid: 0000-0001-5836-5350
- first_name: Mathis
  full_name: Cheve, Mathis
  id: c2cdb722-b15c-11ef-9e63-db902a30b40d
  last_name: Cheve
citation:
  ama: 'Agasthya LN, Muller CJ, Cheve M. Moist convective scaling: Insights from an
    idealised model. <i>Quarterly Journal of the Royal Meteorological Society</i>.
    2025;151(766). doi:<a href="https://doi.org/10.1002/qj.4902">10.1002/qj.4902</a>'
  apa: 'Agasthya, L. N., Muller, C. J., &#38; Cheve, M. (2025). Moist convective scaling:
    Insights from an idealised model. <i>Quarterly Journal of the Royal Meteorological
    Society</i>. Wiley. <a href="https://doi.org/10.1002/qj.4902">https://doi.org/10.1002/qj.4902</a>'
  chicago: 'Agasthya, Lokahith N, Caroline J Muller, and Mathis Cheve. “Moist Convective
    Scaling: Insights from an Idealised Model.” <i>Quarterly Journal of the Royal
    Meteorological Society</i>. Wiley, 2025. <a href="https://doi.org/10.1002/qj.4902">https://doi.org/10.1002/qj.4902</a>.'
  ieee: 'L. N. Agasthya, C. J. Muller, and M. Cheve, “Moist convective scaling: Insights
    from an idealised model,” <i>Quarterly Journal of the Royal Meteorological Society</i>,
    vol. 151, no. 766. Wiley, 2025.'
  ista: 'Agasthya LN, Muller CJ, Cheve M. 2025. Moist convective scaling: Insights
    from an idealised model. Quarterly Journal of the Royal Meteorological Society.
    151(766), e4902.'
  mla: 'Agasthya, Lokahith N., et al. “Moist Convective Scaling: Insights from an
    Idealised Model.” <i>Quarterly Journal of the Royal Meteorological Society</i>,
    vol. 151, no. 766, e4902, Wiley, 2025, doi:<a href="https://doi.org/10.1002/qj.4902">10.1002/qj.4902</a>.'
  short: L.N. Agasthya, C.J. Muller, M. Cheve, Quarterly Journal of the Royal Meteorological
    Society 151 (2025).
corr_author: '1'
das_tickbox: '1'
dataavailabilitystatement: The data that support the findings of this study are available
  from the corresponding author, Lokahith Agasthya, upon reasonable request.
date_created: 2024-12-01T23:01:54Z
date_published: 2025-01-01T00:00:00Z
date_updated: 2026-10-01T09:23:20Z
day: '01'
ddc:
- '550'
department:
- _id: CaMu
doi: 10.1002/qj.4902
ec_funded: 1
external_id:
  isi:
  - '001363135200001'
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fulldoi: https://doi.org/10.1002/qj.4902
has_accepted_license: '1'
intvolume: '       151'
isi: 1
issue: '766'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: 629205d8-2b32-11ec-9570-e1356ff73576
  call_identifier: H2020
  grant_number: '805041'
  name: Organization of CLoUdS, and implications of Tropical  cyclones and for the
    Energetics of the tropics, in current and waRming climate
publication: Quarterly Journal of the Royal Meteorological Society
publication_identifier:
  eissn:
  - 1477-870X
  issn:
  - 0035-9009
publication_status: published
publisher: Wiley
quality_controlled: '1'
researchdata_availability: upon request
scopus_import: '1'
status: public
supplementarymaterial: yes
title: 'Moist convective scaling: Insights from an idealised model'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 151
year: '2025'
...
