---
_id: '14339'
abstract:
- lang: eng
  text: Lateral roots are typically maintained at non-vertical angles with respect
    to gravity. These gravitropic setpoint angles are intriguing because their maintenance
    requires that roots are able to effect growth response both with and against the
    gravity vector, a phenomenon previously attributed to gravitropism acting against
    an antigravitropic offset mechanism. Here we show how the components mediating
    gravitropism in the vertical primary root—PINs and phosphatases acting upon them—are
    reconfigured in their regulation such that lateral root growth at a range of angles
    can be maintained. We show that the ability of Arabidopsis lateral roots to bend
    both downward and upward requires the generation of auxin asymmetries and is driven
    by angle-dependent variation in downward gravitropic auxin flux acting against
    angle-independent upward, antigravitropic flux. Further, we demonstrate a symmetry
    in auxin distribution in lateral roots at gravitropic setpoint angle that can
    be traced back to a net, balanced polarization of PIN3 and PIN7 auxin transporters
    in the columella. These auxin fluxes are shifted by altering PIN protein phosphoregulation
    in the columella, either by introducing PIN3 phosphovariant versions or via manipulation
    of levels of the phosphatase subunit PP2A/RCN1. Finally, we show that auxin, in
    addition to driving lateral root directional growth, acts within the lateral root
    columella to induce more vertical growth by increasing RCN1 levels, causing a
    downward shift in PIN3 localization, thereby diminishing the magnitude of the
    upward, antigravitropic auxin flux.
acknowledgement: We thank D. Weijers, C. Schwechheimer and R. Offringa for generous
  sharing of published and unpublished materials and P. Masson for advice on the use
  of the ARL2 promoter. We are grateful to M. Del Bianco and O. Leyser for critical
  reading of the manuscript. This work was supported by the BBSRC (grants BB/N010124/1
  and BB/R000859/1 to S.K.), the Gatsby Charitable Foundation and the Leverhulme Trust
  (RPG-2018-137 to S.K.).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: S
  full_name: Roychoudhry, S
  last_name: Roychoudhry
- first_name: K
  full_name: Sageman-Furnas, K
  last_name: Sageman-Furnas
- first_name: C
  full_name: Wolverton, C
  last_name: Wolverton
- first_name: Peter
  full_name: Grones, Peter
  id: 399876EC-F248-11E8-B48F-1D18A9856A87
  last_name: Grones
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Gergely
  full_name: Molnar, Gergely
  id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
  last_name: Molnar
- first_name: M
  full_name: De Angelis, M
  last_name: De Angelis
- first_name: HL
  full_name: Goodman, HL
  last_name: Goodman
- first_name: N
  full_name: Capstaff, N
  last_name: Capstaff
- first_name: Lloyd
  full_name: JPB, Lloyd
  last_name: JPB
- first_name: J
  full_name: Mullen, J
  last_name: Mullen
- first_name: R
  full_name: Hangarter, R
  last_name: Hangarter
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: S
  full_name: Kepinski, S
  last_name: Kepinski
citation:
  ama: Roychoudhry S, Sageman-Furnas K, Wolverton C, et al. Antigravitropic PIN polarization
    maintains non-vertical growth in lateral roots. <i>Nature Plants</i>. 2023;9:1500-1513.
    doi:<a href="https://doi.org/10.1038/s41477-023-01478-x">10.1038/s41477-023-01478-x</a>
  apa: Roychoudhry, S., Sageman-Furnas, K., Wolverton, C., Grones, P., Tan, S., Molnar,
    G., … Kepinski, S. (2023). Antigravitropic PIN polarization maintains non-vertical
    growth in lateral roots. <i>Nature Plants</i>. Springer Nature. <a href="https://doi.org/10.1038/s41477-023-01478-x">https://doi.org/10.1038/s41477-023-01478-x</a>
  chicago: Roychoudhry, S, K Sageman-Furnas, C Wolverton, Peter Grones, Shutang Tan,
    Gergely Molnar, M De Angelis, et al. “Antigravitropic PIN Polarization Maintains
    Non-Vertical Growth in Lateral Roots.” <i>Nature Plants</i>. Springer Nature,
    2023. <a href="https://doi.org/10.1038/s41477-023-01478-x">https://doi.org/10.1038/s41477-023-01478-x</a>.
  ieee: S. Roychoudhry <i>et al.</i>, “Antigravitropic PIN polarization maintains
    non-vertical growth in lateral roots,” <i>Nature Plants</i>, vol. 9. Springer
    Nature, pp. 1500–1513, 2023.
  ista: Roychoudhry S, Sageman-Furnas K, Wolverton C, Grones P, Tan S, Molnar G, De
    Angelis M, Goodman H, Capstaff N, JPB L, Mullen J, Hangarter R, Friml J, Kepinski
    S. 2023. Antigravitropic PIN polarization maintains non-vertical growth in lateral
    roots. Nature Plants. 9, 1500–1513.
  mla: Roychoudhry, S., et al. “Antigravitropic PIN Polarization Maintains Non-Vertical
    Growth in Lateral Roots.” <i>Nature Plants</i>, vol. 9, Springer Nature, 2023,
    pp. 1500–13, doi:<a href="https://doi.org/10.1038/s41477-023-01478-x">10.1038/s41477-023-01478-x</a>.
  short: S. Roychoudhry, K. Sageman-Furnas, C. Wolverton, P. Grones, S. Tan, G. Molnar,
    M. De Angelis, H. Goodman, N. Capstaff, L. JPB, J. Mullen, R. Hangarter, J. Friml,
    S. Kepinski, Nature Plants 9 (2023) 1500–1513.
date_created: 2023-09-15T09:56:01Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2024-10-21T06:01:33Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41477-023-01478-x
external_id:
  isi:
  - '001069238800014'
  pmid:
  - '37666965'
file:
- access_level: open_access
  checksum: 3d6d5d5abb937c14a5f6f0afba3b8624
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T10:51:31Z
  date_updated: 2023-09-20T10:51:31Z
  file_id: '14351'
  file_name: 2023_NaturePlants_Roychoudhry.pdf
  file_size: 9647103
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T10:51:31Z
fulldoi: https://doi.org/10.1038/s41477-023-01478-x
has_accepted_license: '1'
intvolume: '         9'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1500-1513
pmid: 1
publication: Nature Plants
publication_identifier:
  issn:
  - 2055-0278
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Antigravitropic PIN polarization maintains non-vertical growth in lateral roots
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2023'
...
---
_id: '14341'
abstract:
- lang: eng
  text: Flows through pipes and channels are, in practice, almost always turbulent,
    and the multiscale eddying motion is responsible for a major part of the encountered
    friction losses and pumping costs1. Conversely, for pulsatile flows, in particular
    for aortic blood flow, turbulence levels remain low despite relatively large peak
    velocities. For aortic blood flow, high turbulence levels are intolerable as they
    would damage the shear-sensitive endothelial cell layer2,3,4,5. Here we show that
    turbulence in ordinary pipe flow is diminished if the flow is driven in a pulsatile
    mode that incorporates all the key features of the cardiac waveform. At Reynolds
    numbers comparable to those of aortic blood flow, turbulence is largely inhibited,
    whereas at much higher speeds, the turbulent drag is reduced by more than 25%.
    This specific operation mode is more efficient when compared with steady driving,
    which is the present situation for virtually all fluid transport processes ranging
    from heating circuits to water, gas and oil pipelines.
acknowledged_ssus:
- _id: M-Shop
- _id: ScienComp
acknowledgement: We acknowledge the assistance of the Miba machine shop and the team
  of the ISTA-HPC cluster. We thank M. Quadrio for the discussions. The work was supported
  by the Simons Foundation (grant no. 662960) and by the Austrian Science Fund (grant
  no. I4188-N30), within Deutsche Forschungsgemeinschaft research unit FOR 2688.
article_processing_charge: No
article_type: original
author:
- first_name: Davide
  full_name: Scarselli, Davide
  id: 40315C30-F248-11E8-B48F-1D18A9856A87
  last_name: Scarselli
  orcid: 0000-0001-5227-4271
- first_name: Jose M
  full_name: Lopez Alonso, Jose M
  id: 40770848-F248-11E8-B48F-1D18A9856A87
  last_name: Lopez Alonso
  orcid: 0000-0002-0384-2022
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. Turbulence suppression by
    cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. 2023;621(7977):71-74.
    doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>
  apa: Scarselli, D., Lopez Alonso, J. M., Varshney, A., &#38; Hof, B. (2023). Turbulence
    suppression by cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>
  chicago: Scarselli, Davide, Jose M Lopez Alonso, Atul Varshney, and Björn Hof. “Turbulence
    Suppression by Cardiac-Cycle-Inspired Driving of Pipe Flow.” <i>Nature</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>.
  ieee: D. Scarselli, J. M. Lopez Alonso, A. Varshney, and B. Hof, “Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow,” <i>Nature</i>, vol. 621, no.
    7977. Springer Nature, pp. 71–74, 2023.
  ista: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. 2023. Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow. Nature. 621(7977), 71–74.
  mla: Scarselli, Davide, et al. “Turbulence Suppression by Cardiac-Cycle-Inspired
    Driving of Pipe Flow.” <i>Nature</i>, vol. 621, no. 7977, Springer Nature, 2023,
    pp. 71–74, doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>.
  short: D. Scarselli, J.M. Lopez Alonso, A. Varshney, B. Hof, Nature 621 (2023) 71–74.
corr_author: '1'
date_created: 2023-09-17T22:01:09Z
date_published: 2023-09-07T00:00:00Z
date_updated: 2025-09-09T12:59:04Z
day: '07'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1038/s41586-023-06399-5
external_id:
  isi:
  - '001168947700009'
  pmid:
  - '37673988'
file:
- access_level: open_access
  checksum: 9c9f172ba0a9a301d76fff4229812464
  content_type: application/pdf
  creator: dernst
  date_created: 2024-06-04T09:24:34Z
  date_updated: 2024-06-04T09:24:34Z
  file_id: '17118'
  file_name: 2023_submittedversion.pdf
  file_size: 3247252
  relation: main_file
  success: 1
file_date_updated: 2024-06-04T09:24:34Z
fulldoi: https://doi.org/10.1038/s41586-023-06399-5
has_accepted_license: '1'
intvolume: '       621'
isi: 1
issue: '7977'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 71-74
pmid: 1
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
  grant_number: '662960'
  name: Revisiting the Turbulence Problem Using Statistical Mechanics
- _id: 238B8092-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: I04188
  name: Instabilities in pulsating pipe flow in complex fluids
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://www.ista.ac.at/en/news/pumping-like-the-heart/
scopus_import: '1'
status: public
title: Turbulence suppression by cardiac-cycle-inspired driving of pipe flow
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 621
year: '2023'
...
---
_id: '14342'
abstract:
- lang: eng
  text: We propose a simple method to measure nonlinear Kerr refractive index in mid-infrared
    frequency range that avoids using sophisticated infrared detectors. Our approach
    is based on using a near-infrared probe beam which interacts with a mid-IR beam
    via wavelength-non-degenerate cross-phase modulation (XPM). By carefully measuring
    XPM-induced spectral modifications in the probe beam and comparing the experimental
    data with simulation results, we extract the value for the non-degenerate Kerr
    index. Finally, in order to obtain the value of degenerate mid-IR Kerr index,
    we use the well-established two-band formalism of Sheik-Bahae et al., which is
    shown to become particularly simple in the limit of low frequencies. The proposed
    technique is complementary to the conventional techniques, such as z-scan, and
    has the advantage of not requiring any mid-infrared detectors.
acknowledgement: The work was supported by IST Austria. The authors would like to
  gratefully acknowledge the help and assistance of Professor John M. Dudley.
article_number: '091104'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Dusan
  full_name: Lorenc, Dusan
  id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87
  last_name: Lorenc
- first_name: Zhanybek
  full_name: Alpichshev, Zhanybek
  id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Alpichshev
  orcid: 0000-0002-7183-5203
citation:
  ama: Lorenc D, Alpichshev Z. Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam. <i>Applied Physics Letters</i>. 2023;123(9).
    doi:<a href="https://doi.org/10.1063/5.0161713">10.1063/5.0161713</a>
  apa: Lorenc, D., &#38; Alpichshev, Z. (2023). Mid-infrared Kerr index evaluation
    via cross-phase modulation with a near-infrared probe beam. <i>Applied Physics
    Letters</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0161713">https://doi.org/10.1063/5.0161713</a>
  chicago: Lorenc, Dusan, and Zhanybek Alpichshev. “Mid-Infrared Kerr Index Evaluation
    via Cross-Phase Modulation with a near-Infrared Probe Beam.” <i>Applied Physics
    Letters</i>. AIP Publishing, 2023. <a href="https://doi.org/10.1063/5.0161713">https://doi.org/10.1063/5.0161713</a>.
  ieee: D. Lorenc and Z. Alpichshev, “Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam,” <i>Applied Physics Letters</i>, vol.
    123, no. 9. AIP Publishing, 2023.
  ista: Lorenc D, Alpichshev Z. 2023. Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam. Applied Physics Letters. 123(9), 091104.
  mla: Lorenc, Dusan, and Zhanybek Alpichshev. “Mid-Infrared Kerr Index Evaluation
    via Cross-Phase Modulation with a near-Infrared Probe Beam.” <i>Applied Physics
    Letters</i>, vol. 123, no. 9, 091104, AIP Publishing, 2023, doi:<a href="https://doi.org/10.1063/5.0161713">10.1063/5.0161713</a>.
  short: D. Lorenc, Z. Alpichshev, Applied Physics Letters 123 (2023).
corr_author: '1'
date_created: 2023-09-17T22:01:09Z
date_published: 2023-08-28T00:00:00Z
date_updated: 2025-09-09T12:58:23Z
day: '28'
ddc:
- '530'
department:
- _id: ZhAl
doi: 10.1063/5.0161713
external_id:
  arxiv:
  - '2306.09043'
  isi:
  - '001145465400004'
file:
- access_level: open_access
  checksum: 89a1b604d58b209fec66c6b6f919ac98
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T11:36:16Z
  date_updated: 2023-09-20T11:36:16Z
  file_id: '14353'
  file_name: 2023_ApplPhysLetter_Lorenc.pdf
  file_size: 1486715
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T11:36:16Z
fulldoi: https://doi.org/10.1063/5.0161713
has_accepted_license: '1'
intvolume: '       123'
isi: 1
issue: '9'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Applied Physics Letters
publication_identifier:
  issn:
  - 0003-6951
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mid-infrared Kerr index evaluation via cross-phase modulation with a near-infrared
  probe beam
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 123
year: '2023'
...
---
_id: '14344'
abstract:
- lang: eng
  text: We study the Hamilton cycle problem with input a random graph G ~ G(n,p) in
    two different settings. In the first one, G is given to us in the form of randomly
    ordered adjacency lists while in the second one, we are given the adjacency matrix
    of G. In each of the two settings we derive a deterministic algorithm that w.h.p.
    either finds a Hamilton cycle or returns a certificate that such a cycle does
    not exist for p = p(n) ≥ 0. The running times of our algorithms are O(n) and  respectively,
    each being best possible in its own setting.
article_processing_charge: No
arxiv: 1
author:
- first_name: Michael
  full_name: Anastos, Michael
  id: 0b2a4358-bb35-11ec-b7b9-e3279b593dbb
  last_name: Anastos
citation:
  ama: 'Anastos M. Fast algorithms for solving the Hamilton cycle problem with high
    probability. In: <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>.
    Vol 2023. Society for Industrial and Applied Mathematics; 2023:2286-2323. doi:<a
    href="https://doi.org/10.1137/1.9781611977554.ch88">10.1137/1.9781611977554.ch88</a>'
  apa: 'Anastos, M. (2023). Fast algorithms for solving the Hamilton cycle problem
    with high probability. In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms</i> (Vol. 2023, pp. 2286–2323). Florence, Italy: Society for Industrial
    and Applied Mathematics. <a href="https://doi.org/10.1137/1.9781611977554.ch88">https://doi.org/10.1137/1.9781611977554.ch88</a>'
  chicago: Anastos, Michael. “Fast Algorithms for Solving the Hamilton Cycle Problem
    with High Probability.” In <i>Proceedings of the Annual ACM-SIAM Symposium on
    Discrete Algorithms</i>, 2023:2286–2323. Society for Industrial and Applied Mathematics,
    2023. <a href="https://doi.org/10.1137/1.9781611977554.ch88">https://doi.org/10.1137/1.9781611977554.ch88</a>.
  ieee: M. Anastos, “Fast algorithms for solving the Hamilton cycle problem with high
    probability,” in <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>,
    Florence, Italy, 2023, vol. 2023, pp. 2286–2323.
  ista: 'Anastos M. 2023. Fast algorithms for solving the Hamilton cycle problem with
    high probability. Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms.
    SODA: Symposium on Discrete Algorithms vol. 2023, 2286–2323.'
  mla: Anastos, Michael. “Fast Algorithms for Solving the Hamilton Cycle Problem with
    High Probability.” <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms</i>, vol. 2023, Society for Industrial and Applied Mathematics, 2023,
    pp. 2286–323, doi:<a href="https://doi.org/10.1137/1.9781611977554.ch88">10.1137/1.9781611977554.ch88</a>.
  short: M. Anastos, in:, Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms, Society for Industrial and Applied Mathematics, 2023, pp. 2286–2323.
conference:
  end_date: 2023-01-25
  location: Florence, Italy
  name: 'SODA: Symposium on Discrete Algorithms'
  start_date: 2023-01-22
corr_author: '1'
date_created: 2023-09-17T22:01:10Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2024-10-09T21:07:01Z
day: '01'
department:
- _id: MaKw
doi: 10.1137/1.9781611977554.ch88
external_id:
  arxiv:
  - '2111.14759'
fulldoi: https://doi.org/10.1137/1.9781611977554.ch88
intvolume: '      2023'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2111.14759
month: '01'
oa: 1
oa_version: Preprint
page: 2286-2323
publication: Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
  isbn:
  - '9781611977554'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast algorithms for solving the Hamilton cycle problem with high probability
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2023
year: '2023'
...
---
_id: '14361'
abstract:
- lang: eng
  text: Whether one considers swarming insects, flocking birds, or bacterial colonies,
    collective motion arises from the coordination of individuals and entails the
    adjustment of their respective velocities. In particular, in close confinements,
    such as those encountered by dense cell populations during development or regeneration,
    collective migration can only arise coordinately. Yet, how individuals unify their
    velocities is often not understood. Focusing on a finite number of cells in circular
    confinements, we identify waves of polymerizing actin that function as a pacemaker
    governing the speed of individual cells. We show that the onset of collective
    motion coincides with the synchronization of the wave nucleation frequencies across
    the population. Employing a simpler and more readily accessible mechanical model
    system of active spheres, we identify the synchronization of the individuals’
    internal oscillators as one of the essential requirements to reach the corresponding
    collective state. The mechanical ‘toy’ experiment illustrates that the global
    synchronous state is achieved by nearest neighbor coupling. We suggest by analogy
    that local coupling and the synchronization of actin waves are essential for the
    emergent, self-organized motion of cell collectives.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: M-Shop
acknowledgement: We thank K. O’Keeffe, E. Hannezo, P. Devreotes, C. Dessalles, and
  E. Martens for discussion and/or critical reading of the manuscript; the Bioimaging
  Facility of ISTA for excellent support, as well as the Life Science Facility and
  the Miba Machine Shop of ISTA. This work was supported by the European Research
  Council (ERC StG 281556 and CoG 724373) to M.S.
article_number: '5633'
article_processing_charge: Yes
article_type: original
author:
- first_name: Michael
  full_name: Riedl, Michael
  id: 3BE60946-F248-11E8-B48F-1D18A9856A87
  last_name: Riedl
  orcid: 0000-0003-4844-6311
- first_name: Isabelle D
  full_name: Mayer, Isabelle D
  id: 61763940-15b2-11ec-abd3-cfaddfbc66b4
  last_name: Mayer
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Riedl M, Mayer ID, Merrin J, Sixt MK, Hof B. Synchronization in collectively
    moving inanimate and living active matter. <i>Nature Communications</i>. 2023;14.
    doi:<a href="https://doi.org/10.1038/s41467-023-41432-1">10.1038/s41467-023-41432-1</a>
  apa: Riedl, M., Mayer, I. D., Merrin, J., Sixt, M. K., &#38; Hof, B. (2023). Synchronization
    in collectively moving inanimate and living active matter. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-023-41432-1">https://doi.org/10.1038/s41467-023-41432-1</a>
  chicago: Riedl, Michael, Isabelle D Mayer, Jack Merrin, Michael K Sixt, and Björn
    Hof. “Synchronization in Collectively Moving Inanimate and Living Active Matter.”
    <i>Nature Communications</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41467-023-41432-1">https://doi.org/10.1038/s41467-023-41432-1</a>.
  ieee: M. Riedl, I. D. Mayer, J. Merrin, M. K. Sixt, and B. Hof, “Synchronization
    in collectively moving inanimate and living active matter,” <i>Nature Communications</i>,
    vol. 14. Springer Nature, 2023.
  ista: Riedl M, Mayer ID, Merrin J, Sixt MK, Hof B. 2023. Synchronization in collectively
    moving inanimate and living active matter. Nature Communications. 14, 5633.
  mla: Riedl, Michael, et al. “Synchronization in Collectively Moving Inanimate and
    Living Active Matter.” <i>Nature Communications</i>, vol. 14, 5633, Springer Nature,
    2023, doi:<a href="https://doi.org/10.1038/s41467-023-41432-1">10.1038/s41467-023-41432-1</a>.
  short: M. Riedl, I.D. Mayer, J. Merrin, M.K. Sixt, B. Hof, Nature Communications
    14 (2023).
corr_author: '1'
date_created: 2023-09-24T22:01:10Z
date_published: 2023-09-13T00:00:00Z
date_updated: 2025-04-14T13:10:03Z
day: '13'
ddc:
- '530'
- '570'
department:
- _id: MiSi
- _id: NanoFab
- _id: BjHo
doi: 10.1038/s41467-023-41432-1
ec_funded: 1
external_id:
  isi:
  - '001087583700030'
  pmid:
  - '37704595'
file:
- access_level: open_access
  checksum: 82d2d4ad736cc8493db8ce45cd313f7b
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-25T08:32:37Z
  date_updated: 2023-09-25T08:32:37Z
  file_id: '14366'
  file_name: 2023_NatureComm_Riedl.pdf
  file_size: 2317272
  relation: main_file
  success: 1
file_date_updated: 2023-09-25T08:32:37Z
fulldoi: https://doi.org/10.1038/s41467-023-41432-1
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281556'
  name: Cytoskeletal force generation and force transduction of migrating leukocytes
- _id: 25FE9508-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '724373'
  name: Cellular Navigation Along Spatial Gradients
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synchronization in collectively moving inanimate and living active matter
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2023'
...
---
_id: '14362'
abstract:
- lang: eng
  text: "Motivated by recent applications to entropy theory in dynamical systems,
    we generalise notions introduced by Matthews and define weakly weighted and componentwise
    weakly weighted (generalised) quasi-metrics. We then systematise and extend to
    full generality the correspondences between these objects and other structures
    arising in theoretical computer science and dynamics. In particular, we study
    the correspondences with weak partial metrics and, if the underlying space is
    a semilattice, with invariant (generalised) quasi-metrics satisfying the descending
    path condition, and with strictly monotone semi(-co-)valuations.\r\nWe conclude
    discussing, for endomorphisms of generalised quasi-metric semilattices, a generalisation
    of both the known intrinsic semilattice entropy and the semigroup entropy."
article_number: '114129'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Ilaria
  full_name: Castellano, Ilaria
  last_name: Castellano
- first_name: Anna
  full_name: Giordano Bruno, Anna
  last_name: Giordano Bruno
- first_name: Nicolò
  full_name: Zava, Nicolò
  id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad
  last_name: Zava
  orcid: 0000-0001-8686-1888
citation:
  ama: Castellano I, Giordano Bruno A, Zava N. Weakly weighted generalised quasi-metric
    spaces and semilattices. <i>Theoretical Computer Science</i>. 2023;977. doi:<a
    href="https://doi.org/10.1016/j.tcs.2023.114129">10.1016/j.tcs.2023.114129</a>
  apa: Castellano, I., Giordano Bruno, A., &#38; Zava, N. (2023). Weakly weighted
    generalised quasi-metric spaces and semilattices. <i>Theoretical Computer Science</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.tcs.2023.114129">https://doi.org/10.1016/j.tcs.2023.114129</a>
  chicago: Castellano, Ilaria, Anna Giordano Bruno, and Nicolò Zava. “Weakly Weighted
    Generalised Quasi-Metric Spaces and Semilattices.” <i>Theoretical Computer Science</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.tcs.2023.114129">https://doi.org/10.1016/j.tcs.2023.114129</a>.
  ieee: I. Castellano, A. Giordano Bruno, and N. Zava, “Weakly weighted generalised
    quasi-metric spaces and semilattices,” <i>Theoretical Computer Science</i>, vol.
    977. Elsevier, 2023.
  ista: Castellano I, Giordano Bruno A, Zava N. 2023. Weakly weighted generalised
    quasi-metric spaces and semilattices. Theoretical Computer Science. 977, 114129.
  mla: Castellano, Ilaria, et al. “Weakly Weighted Generalised Quasi-Metric Spaces
    and Semilattices.” <i>Theoretical Computer Science</i>, vol. 977, 114129, Elsevier,
    2023, doi:<a href="https://doi.org/10.1016/j.tcs.2023.114129">10.1016/j.tcs.2023.114129</a>.
  short: I. Castellano, A. Giordano Bruno, N. Zava, Theoretical Computer Science 977
    (2023).
corr_author: '1'
date_created: 2023-09-24T22:01:11Z
date_published: 2023-10-25T00:00:00Z
date_updated: 2024-10-09T21:07:00Z
day: '25'
department:
- _id: HeEd
doi: 10.1016/j.tcs.2023.114129
external_id:
  arxiv:
  - '2212.08424'
  isi:
  - '001076934000001'
fulldoi: https://doi.org/10.1016/j.tcs.2023.114129
intvolume: '       977'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.48550/arXiv.2212.08424 '
month: '10'
oa: 1
oa_version: Preprint
publication: Theoretical Computer Science
publication_identifier:
  issn:
  - 0304-3975
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weakly weighted generalised quasi-metric spaces and semilattices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 977
year: '2023'
...
---
_id: '14363'
abstract:
- lang: eng
  text: Mitochondrial networks remodel their connectivity, content, and subcellular
    localization to support optimized energy production in conditions of increased
    environmental or cellular stress. Microglia rely on mitochondria to respond to
    these stressors, however our knowledge about mitochondrial networks and their
    adaptations in microglia in vivo is limited. Here, we generate a mouse model that
    selectively labels mitochondria in microglia. We identify that mitochondrial networks
    are more fragmented with increased content and perinuclear localization in vitro
    vs. in vivo. Mitochondrial networks adapt similarly in microglia closest to the
    injury site after optic nerve crush. Preventing microglial UCP2 increase after
    injury by selective knockout induces cellular stress. This results in mitochondrial
    hyperfusion in male microglia, a phenotype absent in females due to circulating
    estrogens. Our results establish the foundation for mitochondrial network analysis
    of microglia in vivo, emphasizing the importance of mitochondrial-based sex effects
    of microglia in other pathologies.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: We thank the Scientific Service Units (SSU) of ISTA through resources
  provided by the Imaging and Optics Facility (IOF), the Lab Support Facility (LSF),
  and the Pre-Clinical Facility (PCF) team, specifically Sonja Haslinger and Michael
  Schunn for excellent mouse colony management and support. This research was supported
  by the FWF Sonderforschungsbereich F83 (to E.E.P). We thank Bálint Nagy, Ryan John
  A. Cubero, Marco Benevento and all members of the Siegert group for constant feedback
  on the project and article.
article_number: '107780'
article_processing_charge: Yes
article_type: original
author:
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: Gloria
  full_name: Colombo, Gloria
  id: 3483CF6C-F248-11E8-B48F-1D18A9856A87
  last_name: Colombo
  orcid: 0000-0001-9434-8902
- first_name: Florianne E
  full_name: Schoot Uiterkamp, Florianne E
  id: 3526230C-F248-11E8-B48F-1D18A9856A87
  last_name: Schoot Uiterkamp
- first_name: Felix
  full_name: Sternberg, Felix
  last_name: Sternberg
- first_name: Alessandro
  full_name: Venturino, Alessandro
  id: 41CB84B2-F248-11E8-B48F-1D18A9856A87
  last_name: Venturino
  orcid: 0000-0003-2356-9403
- first_name: Elena E.
  full_name: Pohl, Elena E.
  last_name: Pohl
- first_name: Sandra
  full_name: Siegert, Sandra
  id: 36ACD32E-F248-11E8-B48F-1D18A9856A87
  last_name: Siegert
  orcid: 0000-0001-8635-0877
citation:
  ama: Maes ME, Colombo G, Schoot Uiterkamp FE, et al. Mitochondrial network adaptations
    of microglia reveal sex-specific stress response after injury and UCP2 knockout.
    <i>iScience</i>. 2023;26(10). doi:<a href="https://doi.org/10.1016/j.isci.2023.107780">10.1016/j.isci.2023.107780</a>
  apa: Maes, M. E., Colombo, G., Schoot Uiterkamp, F. E., Sternberg, F., Venturino,
    A., Pohl, E. E., &#38; Siegert, S. (2023). Mitochondrial network adaptations of
    microglia reveal sex-specific stress response after injury and UCP2 knockout.
    <i>IScience</i>. Elsevier. <a href="https://doi.org/10.1016/j.isci.2023.107780">https://doi.org/10.1016/j.isci.2023.107780</a>
  chicago: Maes, Margaret E, Gloria Colombo, Florianne E Schoot Uiterkamp, Felix Sternberg,
    Alessandro Venturino, Elena E. Pohl, and Sandra Siegert. “Mitochondrial Network
    Adaptations of Microglia Reveal Sex-Specific Stress Response after Injury and
    UCP2 Knockout.” <i>IScience</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.isci.2023.107780">https://doi.org/10.1016/j.isci.2023.107780</a>.
  ieee: M. E. Maes <i>et al.</i>, “Mitochondrial network adaptations of microglia
    reveal sex-specific stress response after injury and UCP2 knockout,” <i>iScience</i>,
    vol. 26, no. 10. Elsevier, 2023.
  ista: Maes ME, Colombo G, Schoot Uiterkamp FE, Sternberg F, Venturino A, Pohl EE,
    Siegert S. 2023. Mitochondrial network adaptations of microglia reveal sex-specific
    stress response after injury and UCP2 knockout. iScience. 26(10), 107780.
  mla: Maes, Margaret E., et al. “Mitochondrial Network Adaptations of Microglia Reveal
    Sex-Specific Stress Response after Injury and UCP2 Knockout.” <i>IScience</i>,
    vol. 26, no. 10, 107780, Elsevier, 2023, doi:<a href="https://doi.org/10.1016/j.isci.2023.107780">10.1016/j.isci.2023.107780</a>.
  short: M.E. Maes, G. Colombo, F.E. Schoot Uiterkamp, F. Sternberg, A. Venturino,
    E.E. Pohl, S. Siegert, IScience 26 (2023).
corr_author: '1'
date_created: 2023-09-24T22:01:11Z
date_published: 2023-10-20T00:00:00Z
date_updated: 2024-10-09T21:07:01Z
day: '20'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1016/j.isci.2023.107780
external_id:
  isi:
  - '001080403500001'
  pmid:
  - '37731609'
file:
- access_level: open_access
  checksum: be1a560efdd96d20712311f4fc54aac2
  content_type: application/pdf
  creator: dernst
  date_created: 2023-11-07T08:53:21Z
  date_updated: 2023-11-07T08:53:21Z
  file_id: '14497'
  file_name: 2023_iScience_Maes.pdf
  file_size: 8197935
  relation: main_file
  success: 1
file_date_updated: 2023-11-07T08:53:21Z
fulldoi: https://doi.org/10.1016/j.isci.2023.107780
has_accepted_license: '1'
intvolume: '        26'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: iScience
publication_identifier:
  eissn:
  - 2589-0042
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mitochondrial network adaptations of microglia reveal sex-specific stress response
  after injury and UCP2 knockout
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2023'
...
---
_id: '14364'
abstract:
- lang: eng
  text: We introduce extension-based proofs, a class of impossibility proofs that
    includes valency arguments. They are modelled as an interaction between a prover
    and a protocol. Using proofs based on combinatorial topology, it has been shown
    that it is impossible to deterministically solve -set agreement among  processes
    or approximate agreement on a cycle of length 4 among  processes in a wait-free
    manner in asynchronous models where processes communicate using objects that can
    be constructed from shared registers. However, it was unknown whether proofs based
    on simpler techniques were possible. We show that these impossibility results
    cannot be obtained by extension-based proofs in the iterated snapshot model and,
    hence, extension-based proofs are limited in power.
acknowledgement: "We would like to thank Valerie King, Toniann Pitassi, and Michael
  Saks for helpful discussions and Shi Hao Liu for his useful feedback.\r\nThis research
  was supported by the Natural Science and Engineering Research Council of Canada
  under grants RGPIN-2015-05080 and RGPIN-2020-04178, a postgraduate scholarship,
  and a postdoctoral fellowship; a University of Toronto postdoctoral fellowship;
  the National Science Foundation under grants CCF-1217921, CCF-1301926, CCF-1637385,
  CCF-1650596, and IIS-1447786; the U.S. Department of Energy under grant ER26116/DE-SC0008923;
  the European Research Council (ERC) under the European Union’s Horizon 2020 research
  and innovation programme grant agreement 805223 ScaleML; and the Oracle and Intel
  corporations. Some of the work on this paper was done while Faith Ellen was visiting
  IST Austria."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: James
  full_name: Aspnes, James
  last_name: Aspnes
- first_name: Faith
  full_name: Ellen, Faith
  last_name: Ellen
- first_name: Rati
  full_name: Gelashvili, Rati
  last_name: Gelashvili
- first_name: Leqi
  full_name: Zhu, Leqi
  id: a2117c59-cee4-11ed-b9d0-874ecf0f8ac5
  last_name: Zhu
citation:
  ama: Alistarh D-A, Aspnes J, Ellen F, Gelashvili R, Zhu L. Why extension-based proofs
    fail. <i>SIAM Journal on Computing</i>. 2023;52(4):913-944. doi:<a href="https://doi.org/10.1137/20M1375851">10.1137/20M1375851</a>
  apa: Alistarh, D.-A., Aspnes, J., Ellen, F., Gelashvili, R., &#38; Zhu, L. (2023).
    Why extension-based proofs fail. <i>SIAM Journal on Computing</i>. Society for
    Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/20M1375851">https://doi.org/10.1137/20M1375851</a>
  chicago: Alistarh, Dan-Adrian, James Aspnes, Faith Ellen, Rati Gelashvili, and Leqi
    Zhu. “Why Extension-Based Proofs Fail.” <i>SIAM Journal on Computing</i>. Society
    for Industrial and Applied Mathematics, 2023. <a href="https://doi.org/10.1137/20M1375851">https://doi.org/10.1137/20M1375851</a>.
  ieee: D.-A. Alistarh, J. Aspnes, F. Ellen, R. Gelashvili, and L. Zhu, “Why extension-based
    proofs fail,” <i>SIAM Journal on Computing</i>, vol. 52, no. 4. Society for Industrial
    and Applied Mathematics, pp. 913–944, 2023.
  ista: Alistarh D-A, Aspnes J, Ellen F, Gelashvili R, Zhu L. 2023. Why extension-based
    proofs fail. SIAM Journal on Computing. 52(4), 913–944.
  mla: Alistarh, Dan-Adrian, et al. “Why Extension-Based Proofs Fail.” <i>SIAM Journal
    on Computing</i>, vol. 52, no. 4, Society for Industrial and Applied Mathematics,
    2023, pp. 913–44, doi:<a href="https://doi.org/10.1137/20M1375851">10.1137/20M1375851</a>.
  short: D.-A. Alistarh, J. Aspnes, F. Ellen, R. Gelashvili, L. Zhu, SIAM Journal
    on Computing 52 (2023) 913–944.
date_created: 2023-09-24T22:01:11Z
date_published: 2023-07-25T00:00:00Z
date_updated: 2025-05-14T11:26:06Z
day: '25'
department:
- _id: DaAl
doi: 10.1137/20M1375851
ec_funded: 1
external_id:
  arxiv:
  - '1811.01421'
  isi:
  - '001082972300004'
fulldoi: https://doi.org/10.1137/20M1375851
intvolume: '        52'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1811.01421
month: '07'
oa: 1
oa_version: Preprint
page: 913-944
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '805223'
  name: Elastic Coordination for Scalable Machine Learning
publication: SIAM Journal on Computing
publication_identifier:
  eissn:
  - 1095-7111
  issn:
  - 0097-5397
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
  record:
  - id: '6676'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Why extension-based proofs fail
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 52
year: '2023'
...
---
OA_place: publisher
_id: '14374'
abstract:
- lang: eng
  text: "Superconductivity has many important applications ranging from levitating
    trains over qubits to MRI scanners. The phenomenon is successfully modeled by
    Bardeen-Cooper-Schrieffer (BCS) theory. From a mathematical perspective, BCS theory
    has been studied extensively for systems without boundary. However, little is
    known in the presence of boundaries. With the help of numerical methods physicists
    observed that the critical temperature may increase in the presence of a boundary.
    The goal of this thesis is to understand the influence of boundaries on the critical
    temperature in BCS theory and to give a first rigorous justification of these
    observations. On the way, we also study two-body Schrödinger operators on domains
    with boundaries and prove additional results for superconductors without boundary.\r\n\r\nBCS
    theory is based on a non-linear functional, where the minimizer indicates whether
    the system is superconducting or in the normal, non-superconducting state. By
    considering the Hessian of the BCS functional at the normal state, one can analyze
    whether the normal state is possibly a minimum of the BCS functional and estimate
    the critical temperature. The Hessian turns out to be a linear operator resembling
    a Schrödinger operator for two interacting particles, but with more complicated
    kinetic energy. As a first step, we study the two-body Schrödinger operator in
    the presence of boundaries.\r\nFor Neumann boundary conditions, we prove that
    the addition of a boundary can create new eigenvalues, which correspond to the
    two particles forming a bound state close to the boundary.\r\n\r\nSecond, we need
    to understand superconductivity in the translation invariant setting. While in
    three dimensions this has been extensively studied, there is no mathematical literature
    for the one and two dimensional cases. In dimensions one and two, we compute the
    weak coupling asymptotics of the critical temperature and the energy gap  in the
    translation invariant setting. We also prove that their ratio is independent of
    the microscopic details of the model in the weak coupling limit; this property
    is referred to as universality.\r\n\r\nIn the third part, we study the critical
    temperature of superconductors in the presence of boundaries. We start by considering
    the one-dimensional case of a half-line with contact interaction. Then, we generalize
    the results to generic interactions and half-spaces in one, two and three dimensions.
    Finally, we compare the critical temperature of a quarter space in two dimensions
    to the critical temperatures of a half-space and of the full space."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Barbara
  full_name: Roos, Barbara
  id: 5DA90512-D80F-11E9-8994-2E2EE6697425
  last_name: Roos
  orcid: 0000-0002-9071-5880
citation:
  ama: Roos B. Boundary superconductivity in BCS theory. 2023. doi:<a href="https://doi.org/10.15479/at:ista:14374">10.15479/at:ista:14374</a>
  apa: Roos, B. (2023). <i>Boundary superconductivity in BCS theory</i>. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/at:ista:14374">https://doi.org/10.15479/at:ista:14374</a>
  chicago: Roos, Barbara. “Boundary Superconductivity in BCS Theory.” Institute of
    Science and Technology Austria, 2023. <a href="https://doi.org/10.15479/at:ista:14374">https://doi.org/10.15479/at:ista:14374</a>.
  ieee: B. Roos, “Boundary superconductivity in BCS theory,” Institute of Science
    and Technology Austria, 2023.
  ista: Roos B. 2023. Boundary superconductivity in BCS theory. Institute of Science
    and Technology Austria.
  mla: Roos, Barbara. <i>Boundary Superconductivity in BCS Theory</i>. Institute of
    Science and Technology Austria, 2023, doi:<a href="https://doi.org/10.15479/at:ista:14374">10.15479/at:ista:14374</a>.
  short: B. Roos, Boundary Superconductivity in BCS Theory, Institute of Science and
    Technology Austria, 2023.
corr_author: '1'
date_created: 2023-09-28T14:23:04Z
date_published: 2023-09-30T00:00:00Z
date_updated: 2026-04-07T13:27:39Z
day: '30'
ddc:
- '515'
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: RoSe
doi: 10.15479/at:ista:14374
ec_funded: 1
file:
- access_level: open_access
  checksum: ef039ffc3de2cb8dee5b14110938e9b6
  content_type: application/pdf
  creator: broos
  date_created: 2023-10-06T11:35:56Z
  date_updated: 2023-10-06T11:35:56Z
  file_id: '14398'
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  file_size: 2365702
  relation: main_file
- access_level: closed
  checksum: 81dcac33daeefaf0111db52f41bb1fd0
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  creator: broos
  date_created: 2023-10-06T11:38:01Z
  date_updated: 2023-10-06T11:38:01Z
  file_id: '14399'
  file_name: Version5.zip
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file_date_updated: 2023-10-06T11:38:01Z
fulldoi: https://doi.org/10.15479/at:ista:14374
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '09'
oa: 1
oa_version: Published Version
page: '206'
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
- _id: bda63fe5-d553-11ed-ba76-a16e3d2f256b
  grant_number: I06427
  name: Mathematical Challenges in BCS Theory of Superconductivity
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '10850'
    relation: part_of_dissertation
    status: public
  - id: '13207'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
title: Boundary superconductivity in BCS theory
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
year: '2023'
...
---
_id: '14378'
abstract:
- lang: eng
  text: 'Branching morphogenesis is a ubiquitous process that gives rise to high exchange
    surfaces in the vasculature and epithelial organs. Lymphatic capillaries form
    branched networks, which play a key role in the circulation of tissue fluid and
    immune cells. Although mouse models and correlative patient data indicate that
    the lymphatic capillary density directly correlates with functional output, i.e.,
    tissue fluid drainage and trafficking efficiency of dendritic cells, the mechanisms
    ensuring efficient tissue coverage remain poorly understood. Here, we use the
    mouse ear pinna lymphatic vessel network as a model system and combine lineage-tracing,
    genetic perturbations, whole-organ reconstructions and theoretical modeling to
    show that the dermal lymphatic capillaries tile space in an optimal, space-filling
    manner. This coverage is achieved by two complementary mechanisms: initial tissue
    invasion provides a non-optimal global scaffold via self-organized branching morphogenesis,
    while VEGF-C dependent side-branching from existing capillaries rapidly optimizes
    local coverage by directionally targeting low-density regions. With these two
    ingredients, we show that a minimal biophysical model can reproduce quantitatively
    whole-network reconstructions, across development and perturbations. Our results
    show that lymphatic capillary networks can exploit local self-organizing mechanisms
    to achieve tissue-scale optimization.'
acknowledgement: "We thank Dr. Kari Alitalo (University of Helsinki and Wihuri Research
  Institute) for critical reading of the manuscript, providing Vegfc+/− and Clp24ΔEC
  mouse strains and for hosting K.V.’s Academy of Finland postdoctoral researcher
  period (2015–2018). We thank Dr. Sara Wickström (University of Helsinki and Wihuri
  Research Institute) for providing Sox9:Egfp mouse\r\nstrain and the discussions.
  We thank Maija Atuegwu and Tapio Tainola for technical assistance. This work received
  funding from the Academy of Finland (K.V., 315710), Sigrid Juselius Foundation (K.V.),
  University of Helsinki (K.V.), Wihuri Research Institute (K.V.), the ERC under the
  European Union’s Horizon 2020 research and innovation program (grant agreement\r\nNo.
  851288 to E.H.) and under the Marie Skłodowska-Curie grant agreement No. 754411
  (to M.C.U.). Part of the work was carried out with the support of HiLIFE Laboratory
  Animal Centre Core Facility, University of Helsinki, Finland. Imaging was performed
  at the Biomedicum Imaging Unit, Helsinki University, Helsinki, Finland, with the
  support of Biocenter Finland. The AAVpreparations were produced at the Helsinki
  Virus (HelVi) Core."
article_number: '5878'
article_processing_charge: Yes
article_type: original
author:
- first_name: Mehmet C
  full_name: Ucar, Mehmet C
  id: 50B2A802-6007-11E9-A42B-EB23E6697425
  last_name: Ucar
  orcid: 0000-0003-0506-4217
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Emmi
  full_name: Tiilikainen, Emmi
  last_name: Tiilikainen
- first_name: Inam
  full_name: Liaqat, Inam
  last_name: Liaqat
- first_name: Emma
  full_name: Jakobsson, Emma
  last_name: Jakobsson
- first_name: Harri
  full_name: Nurmi, Harri
  last_name: Nurmi
- first_name: Kari
  full_name: Vaahtomeri, Kari
  id: 368EE576-F248-11E8-B48F-1D18A9856A87
  last_name: Vaahtomeri
  orcid: 0000-0001-7829-3518
citation:
  ama: Ucar MC, Hannezo EB, Tiilikainen E, et al. Self-organized and directed branching
    results in optimal coverage in developing dermal lymphatic networks. <i>Nature
    Communications</i>. 2023;14. doi:<a href="https://doi.org/10.1038/s41467-023-41456-7">10.1038/s41467-023-41456-7</a>
  apa: Ucar, M. C., Hannezo, E. B., Tiilikainen, E., Liaqat, I., Jakobsson, E., Nurmi,
    H., &#38; Vaahtomeri, K. (2023). Self-organized and directed branching results
    in optimal coverage in developing dermal lymphatic networks. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-023-41456-7">https://doi.org/10.1038/s41467-023-41456-7</a>
  chicago: Ucar, Mehmet C, Edouard B Hannezo, Emmi Tiilikainen, Inam Liaqat, Emma
    Jakobsson, Harri Nurmi, and Kari Vaahtomeri. “Self-Organized and Directed Branching
    Results in Optimal Coverage in Developing Dermal Lymphatic Networks.” <i>Nature
    Communications</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41467-023-41456-7">https://doi.org/10.1038/s41467-023-41456-7</a>.
  ieee: M. C. Ucar <i>et al.</i>, “Self-organized and directed branching results in
    optimal coverage in developing dermal lymphatic networks,” <i>Nature Communications</i>,
    vol. 14. Springer Nature, 2023.
  ista: Ucar MC, Hannezo EB, Tiilikainen E, Liaqat I, Jakobsson E, Nurmi H, Vaahtomeri
    K. 2023. Self-organized and directed branching results in optimal coverage in
    developing dermal lymphatic networks. Nature Communications. 14, 5878.
  mla: Ucar, Mehmet C., et al. “Self-Organized and Directed Branching Results in Optimal
    Coverage in Developing Dermal Lymphatic Networks.” <i>Nature Communications</i>,
    vol. 14, 5878, Springer Nature, 2023, doi:<a href="https://doi.org/10.1038/s41467-023-41456-7">10.1038/s41467-023-41456-7</a>.
  short: M.C. Ucar, E.B. Hannezo, E. Tiilikainen, I. Liaqat, E. Jakobsson, H. Nurmi,
    K. Vaahtomeri, Nature Communications 14 (2023).
corr_author: '1'
date_created: 2023-10-01T22:01:13Z
date_published: 2023-09-21T00:00:00Z
date_updated: 2025-04-14T07:43:56Z
day: '21'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1038/s41467-023-41456-7
ec_funded: 1
external_id:
  isi:
  - '001075884500007'
  pmid:
  - '37735168'
file:
- access_level: open_access
  checksum: 4fe5423403f2531753bcd9e0fea48e05
  content_type: application/pdf
  creator: dernst
  date_created: 2023-10-03T07:46:36Z
  date_updated: 2023-10-03T07:46:36Z
  file_id: '14384'
  file_name: 2023_NatureComm_Ucar.pdf
  file_size: 8143264
  relation: main_file
  success: 1
file_date_updated: 2023-10-03T07:46:36Z
fulldoi: https://doi.org/10.1038/s41467-023-41456-7
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Self-organized and directed branching results in optimal coverage in developing
  dermal lymphatic networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2023'
...
---
_id: '14379'
abstract:
- lang: eng
  text: We report on a simple surfactant/template free chemical route for the synthesis
    of semi-polycrystalline polyaniline-graphite (SPani-graphite) composite and its
    application as an electroactive material in electrochemical charge storage. The
    synthesized material exhibits well-defined poly-crystallographic lattices in high
    resolution transmission electron micrographs and sharp peaks in x-ray diffraction
    spectra suggesting crystalline nature of the material. The specific capacitance
    computed from the galvanostatic charge-discharge (GCD) data obtained from 3-electrode
    cell configuration using 1 M aq. Na2SO4 as an electrolyte was 111.4 F g−1 at a
    current density of 0.1 A g−1 which rises to 269 F g−1 at an elevated current density
    of 1.0 A g−1. A similar pattern of increase in the specific capacitance values
    with an increase in the current density was observed in the results obtained from
    2-electrode symmetric device configuration using polymer gel electrolyte (xanthan
    gum in 1 M aq. Na2SO4). The specific capacitance computed from the GCD data obtained
    from the device configuration was 20 F g−1 at the current density of 1.0 A g−1.
    The device delivers an energy density of 1.7 Wh kg−1 and a power density of 2.48
    kWh kg−1 at an applied current density of 0.5 A g−1 suggesting an excellent rate
    capability and power management. In addition, the device exhibits ⁓92 % specific
    capacitance retention up to 8000 continuous GCD cycles and ⁓80 % coulombic efficiency
    up to 10,000 continuous GCD cycles indicating excellent cycling stability. The
    unique feature of increasing specific capacitance with respect to applied current
    density is attributed to the presence of semi-polycrystalline phases in the SPani-graphite
    matrix. The material behaves as a surface redox supercapacitor and its unique
    mechanism of charge storage is discussed in detail in the article.
acknowledgement: This work was supported by 2023 Yeungnam University Research Grant.
article_number: '117463'
article_processing_charge: No
article_type: original
author:
- first_name: Neelima
  full_name: Mahato, Neelima
  last_name: Mahato
- first_name: Saurabh
  full_name: Singh, Saurabh
  id: 12d625da-9cb3-11ed-9667-af09d37d3f0a
  last_name: Singh
  orcid: 0000-0003-2209-5269
- first_name: Mohammad
  full_name: Faisal, Mohammad
  last_name: Faisal
- first_name: T. V.M.
  full_name: Sreekanth, T. V.M.
  last_name: Sreekanth
- first_name: Sutripto
  full_name: Majumder, Sutripto
  last_name: Majumder
- first_name: Kisoo
  full_name: Yoo, Kisoo
  last_name: Yoo
- first_name: Jonghoon
  full_name: Kim, Jonghoon
  last_name: Kim
citation:
  ama: Mahato N, Singh S, Faisal M, et al. Polycrystalline phases grown in-situ engendering
    unique mechanism of charge storage in polyaniline-graphite composite. <i>Synthetic
    Metals</i>. 2023;299. doi:<a href="https://doi.org/10.1016/j.synthmet.2023.117463">10.1016/j.synthmet.2023.117463</a>
  apa: Mahato, N., Singh, S., Faisal, M., Sreekanth, T. V. M., Majumder, S., Yoo,
    K., &#38; Kim, J. (2023). Polycrystalline phases grown in-situ engendering unique
    mechanism of charge storage in polyaniline-graphite composite. <i>Synthetic Metals</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.synthmet.2023.117463">https://doi.org/10.1016/j.synthmet.2023.117463</a>
  chicago: Mahato, Neelima, Saurabh Singh, Mohammad Faisal, T. V.M. Sreekanth, Sutripto
    Majumder, Kisoo Yoo, and Jonghoon Kim. “Polycrystalline Phases Grown In-Situ Engendering
    Unique Mechanism of Charge Storage in Polyaniline-Graphite Composite.” <i>Synthetic
    Metals</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.synthmet.2023.117463">https://doi.org/10.1016/j.synthmet.2023.117463</a>.
  ieee: N. Mahato <i>et al.</i>, “Polycrystalline phases grown in-situ engendering
    unique mechanism of charge storage in polyaniline-graphite composite,” <i>Synthetic
    Metals</i>, vol. 299. Elsevier, 2023.
  ista: Mahato N, Singh S, Faisal M, Sreekanth TVM, Majumder S, Yoo K, Kim J. 2023.
    Polycrystalline phases grown in-situ engendering unique mechanism of charge storage
    in polyaniline-graphite composite. Synthetic Metals. 299, 117463.
  mla: Mahato, Neelima, et al. “Polycrystalline Phases Grown In-Situ Engendering Unique
    Mechanism of Charge Storage in Polyaniline-Graphite Composite.” <i>Synthetic Metals</i>,
    vol. 299, 117463, Elsevier, 2023, doi:<a href="https://doi.org/10.1016/j.synthmet.2023.117463">10.1016/j.synthmet.2023.117463</a>.
  short: N. Mahato, S. Singh, M. Faisal, T.V.M. Sreekanth, S. Majumder, K. Yoo, J.
    Kim, Synthetic Metals 299 (2023).
date_created: 2023-10-01T22:01:13Z
date_published: 2023-11-01T00:00:00Z
date_updated: 2024-01-30T13:55:50Z
day: '01'
department:
- _id: MaIb
doi: 10.1016/j.synthmet.2023.117463
external_id:
  isi:
  - '001083568900001'
fulldoi: https://doi.org/10.1016/j.synthmet.2023.117463
intvolume: '       299'
isi: 1
language:
- iso: eng
month: '11'
oa_version: None
publication: Synthetic Metals
publication_identifier:
  issn:
  - 0379-6779
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Polycrystalline phases grown in-situ engendering unique mechanism of charge
  storage in polyaniline-graphite composite
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 299
year: '2023'
...
---
_id: '14401'
abstract:
- lang: eng
  text: "Background: \r\nPro-apoptotic BAX is a central mediator of retinal ganglion
    cell (RGC) death after optic nerve damage. BAX activation occurs in two stages
    including translocation of latent BAX to the mitochondrial outer membrane (MOM)
    and then permeabilization of the MOM to facilitate the release of apoptotic signaling
    molecules. As a critical component of RGC death, BAX is an attractive target for
    neuroprotective therapies and an understanding of the kinetics of BAX activation
    and the mechanisms controlling the two stages of this process in RGCs is potentially
    valuable in informing the development of a neuroprotective strategy.\r\nMethods:\r\nThe
    kinetics of BAX translocation were assessed by both static and live-cell imaging
    of a GFP-BAX fusion protein introduced into RGCs using AAV2-mediated gene transfer
    in mice. Activation of BAX was achieved using an acute optic nerve crush (ONC)
    protocol. Live-cell imaging of GFP-BAX was achieved using explants of mouse retina
    harvested 7 days after ONC. Kinetics of translocation in RGCs were compared to
    GFP-BAX translocation in 661W tissue culture cells. Permeabilization of GFP-BAX
    was assessed by staining with the 6A7 monoclonal antibody, which recognizes a
    conformational change in this protein after MOM insertion. Assessment of individual
    kinases associated with both stages of activation was made using small molecule
    inhibitors injected into the vitreous either independently or in concert with
    ONC surgery. The contribution of the Dual Leucine Zipper-JUN-N-Terminal Kinase
    cascade was evaluated using mice with a double conditional knock-out of both Mkk4
    and Mkk7.\r\nResults:\r\nONC induces the translocation of GFP-BAX in RGCs at a
    slower rate and with less intracellular synchronicity than 661W cells, but exhibits
    less variability among mitochondrial foci within a single cell. GFP-BAX was also
    found to translocate in all compartments of an RGC including the dendritic arbor
    and axon. Approximately 6% of translocating RGCs exhibited retrotranslocation
    of BAX immediately following translocation. Unlike tissue culture cells, which
    exhibit simultaneous translocation and permeabilization, RGCs exhibited a significant
    delay between these two stages, similar to detached cells undergoing anoikis.
    Translocation, with minimal permeabilization could be induced in a subset of RGCs
    using an inhibitor of Focal Adhesion Kinase (PF573228). Permeabilization after
    ONC, in a majority of RGCs, could be inhibited with a broad spectrum kinase inhibitor
    (sunitinib) or a selective inhibitor for p38/MAPK14 (SB203580). Intervention of
    DLK-JNK axis signaling abrogated GFP-BAX translocation after ONC.\r\nConclusions:\r\nA
    comparison between BAX activation kinetics in tissue culture cells and in cells
    of a complex tissue environment shows distinct differences indicating that caution
    should be used when translating findings from one condition to the other. RGCs
    exhibit both a delay between translocation and permeabilization and the ability
    for translocated BAX to be retrotranslocated, suggesting several stages at which
    intervention of the activation process could be exploited in the design of a therapeutic
    strategy."
acknowledgement: "The authors would like to thank Mr. Joel Dietz for management of
  the mouse colony and helpful advice for conducting quantitative PCR studies and
  Mr. Santoshi Kinoshita at the Translational Research Initiative in Pathology laboratory
  at the University of Wisconsin-Madison for cutting sections analyzed in this study.\r\nThis
  work was supported by National Eye Institute grants R01 EY030123 (RWN), R01 EY018606
  (RTL), P30 EY016665 (Department of Ophthalmology and Visual Sciences, University
  of Wisconsin-Madison), T32 EY027721 (RJD) and F31 EY030739 (OJM). Additional funding
  was provided by the BrightFocus Foundation (RWN) and unrestricted grants from Research
  to Prevent Blindness, Inc to the Department of Ophthalmology and Visual Sciences
  (University of Wisconsin-Madison) and to the Department of Ophthalmology (University
  of Rochester)."
article_number: '67'
article_processing_charge: Yes
article_type: original
author:
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: Ryan J.
  full_name: Donahue, Ryan J.
  last_name: Donahue
- first_name: Cassandra L.
  full_name: Schlamp, Cassandra L.
  last_name: Schlamp
- first_name: Olivia J.
  full_name: Marola, Olivia J.
  last_name: Marola
- first_name: Richard T.
  full_name: Libby, Richard T.
  last_name: Libby
- first_name: Robert W.
  full_name: Nickells, Robert W.
  last_name: Nickells
citation:
  ama: Maes ME, Donahue RJ, Schlamp CL, Marola OJ, Libby RT, Nickells RW. BAX activation
    in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct
    steps. <i>Molecular Neurodegeneration</i>. 2023;18. doi:<a href="https://doi.org/10.1186/s13024-023-00659-8">10.1186/s13024-023-00659-8</a>
  apa: Maes, M. E., Donahue, R. J., Schlamp, C. L., Marola, O. J., Libby, R. T., &#38;
    Nickells, R. W. (2023). BAX activation in mouse retinal ganglion cells occurs
    in two temporally and mechanistically distinct steps. <i>Molecular Neurodegeneration</i>.
    Springer Nature. <a href="https://doi.org/10.1186/s13024-023-00659-8">https://doi.org/10.1186/s13024-023-00659-8</a>
  chicago: Maes, Margaret E, Ryan J. Donahue, Cassandra L. Schlamp, Olivia J. Marola,
    Richard T. Libby, and Robert W. Nickells. “BAX Activation in Mouse Retinal Ganglion
    Cells Occurs in Two Temporally and Mechanistically Distinct Steps.” <i>Molecular
    Neurodegeneration</i>. Springer Nature, 2023. <a href="https://doi.org/10.1186/s13024-023-00659-8">https://doi.org/10.1186/s13024-023-00659-8</a>.
  ieee: M. E. Maes, R. J. Donahue, C. L. Schlamp, O. J. Marola, R. T. Libby, and R.
    W. Nickells, “BAX activation in mouse retinal ganglion cells occurs in two temporally
    and mechanistically distinct steps,” <i>Molecular Neurodegeneration</i>, vol.
    18. Springer Nature, 2023.
  ista: Maes ME, Donahue RJ, Schlamp CL, Marola OJ, Libby RT, Nickells RW. 2023. BAX
    activation in mouse retinal ganglion cells occurs in two temporally and mechanistically
    distinct steps. Molecular Neurodegeneration. 18, 67.
  mla: Maes, Margaret E., et al. “BAX Activation in Mouse Retinal Ganglion Cells Occurs
    in Two Temporally and Mechanistically Distinct Steps.” <i>Molecular Neurodegeneration</i>,
    vol. 18, 67, Springer Nature, 2023, doi:<a href="https://doi.org/10.1186/s13024-023-00659-8">10.1186/s13024-023-00659-8</a>.
  short: M.E. Maes, R.J. Donahue, C.L. Schlamp, O.J. Marola, R.T. Libby, R.W. Nickells,
    Molecular Neurodegeneration 18 (2023).
date_created: 2023-10-08T22:01:15Z
date_published: 2023-09-26T00:00:00Z
date_updated: 2025-04-23T13:09:05Z
day: '26'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1186/s13024-023-00659-8
external_id:
  isi:
  - '001071403800001'
  pmid:
  - '37752598'
file:
- access_level: open_access
  checksum: 3aa218ddea4a082d8fd5e196ae55ca06
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-30T14:33:31Z
  date_updated: 2024-01-30T14:33:31Z
  file_id: '14917'
  file_name: 2023_MolecularNeurodegeneration_Maes.pdf
  file_size: 11568350
  relation: main_file
  success: 1
file_date_updated: 2024-01-30T14:33:31Z
fulldoi: https://doi.org/10.1186/s13024-023-00659-8
has_accepted_license: '1'
intvolume: '        18'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Molecular Neurodegeneration
publication_identifier:
  eissn:
  - 1750-1326
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: BAX activation in mouse retinal ganglion cells occurs in two temporally and
  mechanistically distinct steps
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2023'
...
---
_id: '14404'
abstract:
- lang: eng
  text: A light-triggered fabrication method extends the functionality of printable
    nanomaterials
acknowledgement: The authors thank the Werner-Siemens-Stiftung and the Institute of
  Science and Technology Austria for financial support.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Daniel
  full_name: Balazs, Daniel
  id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E
  last_name: Balazs
  orcid: 0000-0001-7597-043X
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
citation:
  ama: Balazs D, Ibáñez M. Widening the use of 3D printing. <i>Science</i>. 2023;381(6665):1413-1414.
    doi:<a href="https://doi.org/10.1126/science.adk3070">10.1126/science.adk3070</a>
  apa: Balazs, D., &#38; Ibáñez, M. (2023). Widening the use of 3D printing. <i>Science</i>.
    AAAS. <a href="https://doi.org/10.1126/science.adk3070">https://doi.org/10.1126/science.adk3070</a>
  chicago: Balazs, Daniel, and Maria Ibáñez. “Widening the Use of 3D Printing.” <i>Science</i>.
    AAAS, 2023. <a href="https://doi.org/10.1126/science.adk3070">https://doi.org/10.1126/science.adk3070</a>.
  ieee: D. Balazs and M. Ibáñez, “Widening the use of 3D printing,” <i>Science</i>,
    vol. 381, no. 6665. AAAS, pp. 1413–1414, 2023.
  ista: Balazs D, Ibáñez M. 2023. Widening the use of 3D printing. Science. 381(6665),
    1413–1414.
  mla: Balazs, Daniel, and Maria Ibáñez. “Widening the Use of 3D Printing.” <i>Science</i>,
    vol. 381, no. 6665, AAAS, 2023, pp. 1413–14, doi:<a href="https://doi.org/10.1126/science.adk3070">10.1126/science.adk3070</a>.
  short: D. Balazs, M. Ibáñez, Science 381 (2023) 1413–1414.
corr_author: '1'
date_created: 2023-10-08T22:01:16Z
date_published: 2023-09-29T00:00:00Z
date_updated: 2025-09-09T13:04:47Z
day: '29'
department:
- _id: MaIb
- _id: LifeSc
doi: 10.1126/science.adk3070
external_id:
  isi:
  - '001100656800023'
  pmid:
  - '37769110'
fulldoi: https://doi.org/10.1126/science.adk3070
intvolume: '       381'
isi: 1
issue: '6665'
language:
- iso: eng
month: '09'
oa_version: None
page: 1413-1414
pmid: 1
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Widening the use of 3D printing
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 381
year: '2023'
...
---
_id: '14405'
abstract:
- lang: eng
  text: We introduce hypernode automata as a new specification formalism for hyperproperties
    of concurrent systems. They are finite automata with nodes labeled with hypernode
    logic formulas and transitions labeled with actions. A hypernode logic formula
    specifies relations between sequences of variable values in different system executions.
    Unlike HyperLTL, hypernode logic takes an asynchronous view on execution traces
    by constraining the values and the order of value changes of each variable without
    correlating the timing of the changes. Different execution traces are synchronized
    solely through the transitions of hypernode automata. Hypernode automata naturally
    combine asynchronicity at the node level with synchronicity at the transition
    level. We show that the model-checking problem for hypernode automata is decidable
    over action-labeled Kripke structures, whose actions induce transitions of the
    specification automata. For this reason, hypernode automaton is a suitable formalism
    for specifying and verifying asynchronous hyperproperties, such as declassifying
    observational determinism in multi-threaded programs.
acknowledgement: "This work was supported in part by the Austrian Science Fund (FWF)
  SFB project\r\nSpyCoDe F8502, by the FWF projects ZK-35 and W1255-N23, and by the
  ERC Advanced Grant\r\nVAMOS 101020093."
alternative_title:
- LIPIcs
article_number: '21'
article_processing_charge: Yes
arxiv: 1
author:
- first_name: Ezio
  full_name: Bartocci, Ezio
  last_name: Bartocci
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Dejan
  full_name: Nickovic, Dejan
  id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
  last_name: Nickovic
- first_name: Ana
  full_name: Oliveira da Costa, Ana
  id: f347ec37-6676-11ee-b395-a888cb7b4fb4
  last_name: Oliveira da Costa
  orcid: 0000-0002-8741-5799
citation:
  ama: 'Bartocci E, Henzinger TA, Nickovic D, Oliveira da Costa A. Hypernode automata.
    In: <i>34th International Conference on Concurrency Theory</i>. Vol 279. Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik; 2023. doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2023.21">10.4230/LIPIcs.CONCUR.2023.21</a>'
  apa: 'Bartocci, E., Henzinger, T. A., Nickovic, D., &#38; Oliveira da Costa, A.
    (2023). Hypernode automata. In <i>34th International Conference on Concurrency
    Theory</i> (Vol. 279). Antwerp, Belgium: Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik. <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2023.21">https://doi.org/10.4230/LIPIcs.CONCUR.2023.21</a>'
  chicago: Bartocci, Ezio, Thomas A Henzinger, Dejan Nickovic, and Ana Oliveira da
    Costa. “Hypernode Automata.” In <i>34th International Conference on Concurrency
    Theory</i>, Vol. 279. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2023.
    <a href="https://doi.org/10.4230/LIPIcs.CONCUR.2023.21">https://doi.org/10.4230/LIPIcs.CONCUR.2023.21</a>.
  ieee: E. Bartocci, T. A. Henzinger, D. Nickovic, and A. Oliveira da Costa, “Hypernode
    automata,” in <i>34th International Conference on Concurrency Theory</i>, Antwerp,
    Belgium, 2023, vol. 279.
  ista: 'Bartocci E, Henzinger TA, Nickovic D, Oliveira da Costa A. 2023. Hypernode
    automata. 34th International Conference on Concurrency Theory. CONCUR: Conference
    on Concurrency Theory, LIPIcs, vol. 279, 21.'
  mla: Bartocci, Ezio, et al. “Hypernode Automata.” <i>34th International Conference
    on Concurrency Theory</i>, vol. 279, 21, Schloss Dagstuhl - Leibniz-Zentrum für
    Informatik, 2023, doi:<a href="https://doi.org/10.4230/LIPIcs.CONCUR.2023.21">10.4230/LIPIcs.CONCUR.2023.21</a>.
  short: E. Bartocci, T.A. Henzinger, D. Nickovic, A. Oliveira da Costa, in:, 34th
    International Conference on Concurrency Theory, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2023.
conference:
  end_date: 2023-09-22
  location: Antwerp, Belgium
  name: 'CONCUR: Conference on Concurrency Theory'
  start_date: 2023-09-19
corr_author: '1'
date_created: 2023-10-08T22:01:16Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2026-01-05T12:27:40Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.4230/LIPIcs.CONCUR.2023.21
ec_funded: 1
external_id:
  arxiv:
  - '2305.02836'
file:
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  creator: dernst
  date_created: 2023-10-09T07:42:45Z
  date_updated: 2023-10-09T07:42:45Z
  file_id: '14413'
  file_name: 2023_LIPcs_Bartocci.pdf
  file_size: 795790
  relation: main_file
  success: 1
file_date_updated: 2023-10-09T07:42:45Z
fulldoi: https://doi.org/10.4230/LIPIcs.CONCUR.2023.21
has_accepted_license: '1'
intvolume: '       279'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication: 34th International Conference on Concurrency Theory
publication_identifier:
  isbn:
  - '9783959772990'
  issn:
  - 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
  record:
  - id: '20866'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Hypernode automata
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 279
year: '2023'
...
---
_id: '14406'
abstract:
- lang: eng
  text: "Recently, a concept of generalized multifractality, which characterizes fluctuations
    and correlations of critical eigenstates, was introduced and explored for all
    10 symmetry classes of disordered systems. Here, by using the nonlinear sigma-model
    (\r\nNL\r\nσ\r\nM\r\n) field theory, we extend the theory of generalized multifractality
    to boundaries of systems at criticality. Our numerical simulations on two-dimensional
    systems of symmetry classes A, C, and AII fully confirm the analytical predictions
    of pure-scaling observables and Weyl symmetry relations between critical exponents
    of surface generalized multifractality. This demonstrates the validity of the
    \r\nNL\r\nσ\r\nM\r\n for the description of Anderson-localization critical phenomena,
    not only in the bulk but also on the boundary. The critical exponents strongly
    violate generalized parabolicity, in analogy with earlier results for the bulk,
    corroborating the conclusion that the considered Anderson-localization critical
    points are not described by conformal field theories. We further derive relations
    between generalized surface multifractal spectra and linear combinations of Lyapunov
    exponents of a strip in quasi-one-dimensional geometry, which hold under the assumption
    of invariance with respect to a logarithmic conformal map. Our numerics demonstrate
    that these relations hold with an excellent accuracy. Taken together, our results
    indicate an intriguing situation: the conformal invariance is broken but holds
    partially at critical points of Anderson localization."
acknowledgement: "We thank Ilya Gruzberg for many illuminating discussions. S.S.B.,
  J.F.K., and A.D.M. acknowledge support by the Deutsche Forschungsgemeinschaft (DFG)
  via the Grant\r\nNo. MI 658/14-1. I.S.B. acknowledges support from Russian Science
  Foundation (Grant No. 22-42-04416)."
article_number: '104205'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Serafim
  full_name: Babkin, Serafim
  id: 41e64307-6672-11ee-b9ad-cc7a0075a479
  last_name: Babkin
  orcid: 0009-0003-7382-8036
- first_name: Jonas F.
  full_name: Karcher, Jonas F.
  last_name: Karcher
- first_name: Igor S.
  full_name: Burmistrov, Igor S.
  last_name: Burmistrov
- first_name: Alexander D.
  full_name: Mirlin, Alexander D.
  last_name: Mirlin
citation:
  ama: Babkin S, Karcher JF, Burmistrov IS, Mirlin AD. Generalized surface multifractality
    in two-dimensional disordered systems. <i>Physical Review B</i>. 2023;108(10).
    doi:<a href="https://doi.org/10.1103/PhysRevB.108.104205">10.1103/PhysRevB.108.104205</a>
  apa: Babkin, S., Karcher, J. F., Burmistrov, I. S., &#38; Mirlin, A. D. (2023).
    Generalized surface multifractality in two-dimensional disordered systems. <i>Physical
    Review B</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevB.108.104205">https://doi.org/10.1103/PhysRevB.108.104205</a>
  chicago: Babkin, Serafim, Jonas F. Karcher, Igor S. Burmistrov, and Alexander D.
    Mirlin. “Generalized Surface Multifractality in Two-Dimensional Disordered Systems.”
    <i>Physical Review B</i>. American Physical Society, 2023. <a href="https://doi.org/10.1103/PhysRevB.108.104205">https://doi.org/10.1103/PhysRevB.108.104205</a>.
  ieee: S. Babkin, J. F. Karcher, I. S. Burmistrov, and A. D. Mirlin, “Generalized
    surface multifractality in two-dimensional disordered systems,” <i>Physical Review
    B</i>, vol. 108, no. 10. American Physical Society, 2023.
  ista: Babkin S, Karcher JF, Burmistrov IS, Mirlin AD. 2023. Generalized surface
    multifractality in two-dimensional disordered systems. Physical Review B. 108(10),
    104205.
  mla: Babkin, Serafim, et al. “Generalized Surface Multifractality in Two-Dimensional
    Disordered Systems.” <i>Physical Review B</i>, vol. 108, no. 10, 104205, American
    Physical Society, 2023, doi:<a href="https://doi.org/10.1103/PhysRevB.108.104205">10.1103/PhysRevB.108.104205</a>.
  short: S. Babkin, J.F. Karcher, I.S. Burmistrov, A.D. Mirlin, Physical Review B
    108 (2023).
date_created: 2023-10-08T22:01:17Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2025-09-09T13:03:44Z
day: '01'
department:
- _id: MaSe
doi: 10.1103/PhysRevB.108.104205
external_id:
  arxiv:
  - '2306.09455'
  isi:
  - '001186160100001'
fulldoi: https://doi.org/10.1103/PhysRevB.108.104205
intvolume: '       108'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2306.09455
month: '09'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized surface multifractality in two-dimensional disordered systems
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 108
year: '2023'
...
---
_id: '14409'
abstract:
- lang: eng
  text: We present a photon- and metal-free approach for the radical fluorination
    of aliphatic oxalate-activated alcohols. The method relies on the spontaneous
    generation of the N-(chloromethyl)triethylenediamine radical dication, a potent
    single electron oxidant, from Selectfluor and 4-(dimethylamino)pyridine. The protocol
    is easily scalable and provides the desired fluorinated products within only a
    few minutes reaction time.
acknowledgement: We gratefully acknowledge the Max-Planck Society and the Institute
  of Science and Technology Austria (ISTA) for generous financial support. We also
  thank the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under
  Germany's Excellence Strategy – EXC 2008 – 390540038 – UniSysCat for funding. B.P.
  thanks the Boehringer Ingelheim Foundation for funding through the Plus 3 Perspectives
  Programme.
article_number: e202300769
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Haralds
  full_name: Baunis, Haralds
  id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe
  last_name: Baunis
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
citation:
  ama: Baunis H, Pieber B. Formal radical deoxyfluorination of oxalate-activated alcohols
    triggered by the selectfluor-DMAP charge-transfer complex. <i>European Journal
    of Organic Chemistry</i>. 2023;26(42). doi:<a href="https://doi.org/10.1002/ejoc.202300769">10.1002/ejoc.202300769</a>
  apa: Baunis, H., &#38; Pieber, B. (2023). Formal radical deoxyfluorination of oxalate-activated
    alcohols triggered by the selectfluor-DMAP charge-transfer complex. <i>European
    Journal of Organic Chemistry</i>. Wiley. <a href="https://doi.org/10.1002/ejoc.202300769">https://doi.org/10.1002/ejoc.202300769</a>
  chicago: Baunis, Haralds, and Bartholomäus Pieber. “Formal Radical Deoxyfluorination
    of Oxalate-Activated Alcohols Triggered by the Selectfluor-DMAP Charge-Transfer
    Complex.” <i>European Journal of Organic Chemistry</i>. Wiley, 2023. <a href="https://doi.org/10.1002/ejoc.202300769">https://doi.org/10.1002/ejoc.202300769</a>.
  ieee: H. Baunis and B. Pieber, “Formal radical deoxyfluorination of oxalate-activated
    alcohols triggered by the selectfluor-DMAP charge-transfer complex,” <i>European
    Journal of Organic Chemistry</i>, vol. 26, no. 42. Wiley, 2023.
  ista: Baunis H, Pieber B. 2023. Formal radical deoxyfluorination of oxalate-activated
    alcohols triggered by the selectfluor-DMAP charge-transfer complex. European Journal
    of Organic Chemistry. 26(42), e202300769.
  mla: Baunis, Haralds, and Bartholomäus Pieber. “Formal Radical Deoxyfluorination
    of Oxalate-Activated Alcohols Triggered by the Selectfluor-DMAP Charge-Transfer
    Complex.” <i>European Journal of Organic Chemistry</i>, vol. 26, no. 42, e202300769,
    Wiley, 2023, doi:<a href="https://doi.org/10.1002/ejoc.202300769">10.1002/ejoc.202300769</a>.
  short: H. Baunis, B. Pieber, European Journal of Organic Chemistry 26 (2023).
corr_author: '1'
date_created: 2023-10-08T22:01:18Z
date_published: 2023-11-07T00:00:00Z
date_updated: 2024-10-09T21:07:03Z
day: '07'
ddc:
- '540'
department:
- _id: BaPi
doi: 10.1002/ejoc.202300769
external_id:
  isi:
  - '001072666500001'
file:
- access_level: open_access
  checksum: e8ad7865acd94672e476f273ccf3d542
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-30T14:04:44Z
  date_updated: 2024-01-30T14:04:44Z
  file_id: '14913'
  file_name: 2023_EurJOrgChem_Baunis.pdf
  file_size: 3277622
  relation: main_file
  success: 1
file_date_updated: 2024-01-30T14:04:44Z
fulldoi: https://doi.org/10.1002/ejoc.202300769
has_accepted_license: '1'
intvolume: '        26'
isi: 1
issue: '42'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: European Journal of Organic Chemistry
publication_identifier:
  eissn:
  - 1099-0690
  issn:
  - 1434-193X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Formal radical deoxyfluorination of oxalate-activated alcohols triggered by
  the selectfluor-DMAP charge-transfer complex
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2023'
...
---
_id: '14410'
abstract:
- lang: eng
  text: This paper focuses on the implementation details of the baseline methods and
    a recent lightweight conditional model extrapolation algorithm LIMES [5] for streaming
    data under class-prior shift. LIMES achieves superior performance over the baseline
    methods, especially concerning the minimum-across-day accuracy, which is important
    for the users of the system. In this work, the key measures to facilitate reproducibility
    and enhance the credibility of the results are described.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Paulina
  full_name: Tomaszewska, Paulina
  last_name: Tomaszewska
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Tomaszewska P, Lampert C. On the implementation of baselines and lightweight
    conditional model extrapolation (LIMES) under class-prior shift. In: <i>International
    Workshop on Reproducible Research in Pattern Recognition</i>. Vol 14068. Springer
    Nature; 2023:67-73. doi:<a href="https://doi.org/10.1007/978-3-031-40773-4_6">10.1007/978-3-031-40773-4_6</a>'
  apa: 'Tomaszewska, P., &#38; Lampert, C. (2023). On the implementation of baselines
    and lightweight conditional model extrapolation (LIMES) under class-prior shift.
    In <i>International Workshop on Reproducible Research in Pattern Recognition</i>
    (Vol. 14068, pp. 67–73). Montreal, Canada: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-40773-4_6">https://doi.org/10.1007/978-3-031-40773-4_6</a>'
  chicago: Tomaszewska, Paulina, and Christoph Lampert. “On the Implementation of Baselines
    and Lightweight Conditional Model Extrapolation (LIMES) under Class-Prior Shift.”
    In <i>International Workshop on Reproducible Research in Pattern Recognition</i>,
    14068:67–73. Springer Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-40773-4_6">https://doi.org/10.1007/978-3-031-40773-4_6</a>.
  ieee: P. Tomaszewska and C. Lampert, “On the implementation of baselines and lightweight
    conditional model extrapolation (LIMES) under class-prior shift,” in <i>International
    Workshop on Reproducible Research in Pattern Recognition</i>, Montreal, Canada,
    2023, vol. 14068, pp. 67–73.
  ista: 'Tomaszewska P, Lampert C. 2023. On the implementation of baselines and lightweight
    conditional model extrapolation (LIMES) under class-prior shift. International
    Workshop on Reproducible Research in Pattern Recognition. RRPR: Reproducible Research
    in Pattern Recognition, LNCS, vol. 14068, 67–73.'
  mla: Tomaszewska, Paulina, and Christoph Lampert. “On the Implementation of Baselines
    and Lightweight Conditional Model Extrapolation (LIMES) under Class-Prior Shift.”
    <i>International Workshop on Reproducible Research in Pattern Recognition</i>,
    vol. 14068, Springer Nature, 2023, pp. 67–73, doi:<a href="https://doi.org/10.1007/978-3-031-40773-4_6">10.1007/978-3-031-40773-4_6</a>.
  short: P. Tomaszewska, C. Lampert, in:, International Workshop on Reproducible Research
    in Pattern Recognition, Springer Nature, 2023, pp. 67–73.
conference:
  end_date: 2022-08-21
  location: Montreal, Canada
  name: 'RRPR: Reproducible Research in Pattern Recognition'
  start_date: 2022-08-21
date_created: 2023-10-08T22:01:18Z
date_published: 2023-08-20T00:00:00Z
date_updated: 2023-10-09T06:48:02Z
day: '20'
department:
- _id: ChLa
doi: 10.1007/978-3-031-40773-4_6
fulldoi: https://doi.org/10.1007/978-3-031-40773-4_6
intvolume: '     14068'
language:
- iso: eng
month: '08'
oa_version: None
page: 67-73
publication: International Workshop on Reproducible Research in Pattern Recognition
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783031407727'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the implementation of baselines and lightweight conditional model extrapolation
  (LIMES) under class-prior shift
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14068
year: '2023'
...
---
_id: '14411'
abstract:
- lang: eng
  text: "Partially specified Boolean networks (PSBNs) represent a promising framework
    for the qualitative modelling of biological systems in which the logic of interactions
    is not completely known. Phenotype control aims to stabilise the network in states
    exhibiting specific traits.\r\nIn this paper, we define the phenotype control
    problem in the context of asynchronous PSBNs and propose a novel semi-symbolic
    algorithm for solving this problem with permanent variable perturbations."
acknowledgement: This work was supported by the Czech Foundation grant No. GA22-10845S,
  Grant Agency of Masaryk University grant No. MUNI/G/1771/2020, and the European
  Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
  Grant Agreement No. 101034413.
alternative_title:
- LNBI
article_processing_charge: No
author:
- first_name: Nikola
  full_name: Beneš, Nikola
  last_name: Beneš
- first_name: Luboš
  full_name: Brim, Luboš
  last_name: Brim
- first_name: Samuel
  full_name: Pastva, Samuel
  id: 07c5ea74-f61c-11ec-a664-aa7c5d957b2b
  last_name: Pastva
  orcid: 0000-0003-1993-0331
- first_name: David
  full_name: Šafránek, David
  last_name: Šafránek
- first_name: Eva
  full_name: Šmijáková, Eva
  last_name: Šmijáková
citation:
  ama: 'Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. Phenotype control of partially
    specified boolean networks. In: <i>21st International Conference on Computational
    Methods in Systems Biology</i>. Vol 14137. Springer Nature; 2023:18-35. doi:<a
    href="https://doi.org/10.1007/978-3-031-42697-1_2">10.1007/978-3-031-42697-1_2</a>'
  apa: 'Beneš, N., Brim, L., Pastva, S., Šafránek, D., &#38; Šmijáková, E. (2023).
    Phenotype control of partially specified boolean networks. In <i>21st International
    Conference on Computational Methods in Systems Biology</i> (Vol. 14137, pp. 18–35).
    Luxembourg City, Luxembourg: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-42697-1_2">https://doi.org/10.1007/978-3-031-42697-1_2</a>'
  chicago: Beneš, Nikola, Luboš Brim, Samuel Pastva, David Šafránek, and Eva Šmijáková.
    “Phenotype Control of Partially Specified Boolean Networks.” In <i>21st International
    Conference on Computational Methods in Systems Biology</i>, 14137:18–35. Springer
    Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-42697-1_2">https://doi.org/10.1007/978-3-031-42697-1_2</a>.
  ieee: N. Beneš, L. Brim, S. Pastva, D. Šafránek, and E. Šmijáková, “Phenotype control
    of partially specified boolean networks,” in <i>21st International Conference
    on Computational Methods in Systems Biology</i>, Luxembourg City, Luxembourg,
    2023, vol. 14137, pp. 18–35.
  ista: 'Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. 2023. Phenotype control
    of partially specified boolean networks. 21st International Conference on Computational
    Methods in Systems Biology. CMSB: Computational Methods in Systems Biology, LNBI,
    vol. 14137, 18–35.'
  mla: Beneš, Nikola, et al. “Phenotype Control of Partially Specified Boolean Networks.”
    <i>21st International Conference on Computational Methods in Systems Biology</i>,
    vol. 14137, Springer Nature, 2023, pp. 18–35, doi:<a href="https://doi.org/10.1007/978-3-031-42697-1_2">10.1007/978-3-031-42697-1_2</a>.
  short: N. Beneš, L. Brim, S. Pastva, D. Šafránek, E. Šmijáková, in:, 21st International
    Conference on Computational Methods in Systems Biology, Springer Nature, 2023,
    pp. 18–35.
conference:
  end_date: 2023-09-15
  location: Luxembourg City, Luxembourg
  name: 'CMSB: Computational Methods in Systems Biology'
  start_date: 2023-09-13
date_created: 2023-10-08T22:01:18Z
date_published: 2023-09-09T00:00:00Z
date_updated: 2025-09-09T14:25:46Z
day: '09'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.1007/978-3-031-42697-1_2
ec_funded: 1
external_id:
  isi:
  - '001156280600002'
file:
- access_level: open_access
  checksum: 6f71bdaedb770b52380222fd9f4d7937
  content_type: application/pdf
  creator: spastva
  date_created: 2024-02-16T08:26:32Z
  date_updated: 2024-02-16T08:26:32Z
  file_id: '14997'
  file_name: cmsb2023.pdf
  file_size: 691582
  relation: main_file
  success: 1
file_date_updated: 2024-02-16T08:26:32Z
fulldoi: https://doi.org/10.1007/978-3-031-42697-1_2
has_accepted_license: '1'
intvolume: '     14137'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 18-35
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: 21st International Conference on Computational Methods in Systems Biology
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783031426964'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phenotype control of partially specified boolean networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 14137
year: '2023'
...
---
_id: '14426'
abstract:
- lang: eng
  text: To meet the physiological demands of the body, organs need to establish a
    functional tissue architecture and adequate size as the embryo develops to adulthood.
    In the liver, uni- and bipotent progenitor differentiation into hepatocytes and
    biliary epithelial cells (BECs), and their relative proportions, comprise the
    functional architecture. Yet, the contribution of individual liver progenitors
    at the organ level to both fates, and their specific proportion, is unresolved.
    Combining mathematical modelling with organ-wide, multispectral FRaeppli-NLS lineage
    tracing in zebrafish, we demonstrate that a precise BEC-to-hepatocyte ratio is
    established (i) fast, (ii) solely by heterogeneous lineage decisions from uni-
    and bipotent progenitors, and (iii) independent of subsequent cell type–specific
    proliferation. Extending lineage tracing to adulthood determined that embryonic
    cells undergo spatially heterogeneous three-dimensional growth associated with
    distinct environments. Strikingly, giant clusters comprising almost half a ventral
    lobe suggest lobe-specific dominant-like growth behaviours. We show substantial
    hepatocyte polyploidy in juveniles representing another hallmark of postembryonic
    liver growth. Our findings uncover heterogeneous progenitor contributions to tissue
    architecture-defining cell type proportions and postembryonic organ growth as
    key mechanisms forming the adult liver.
acknowledgement: "We thank the Ober group for discussion and comments on the manuscript.
  We are grateful to\r\nDr. F. Lemaigre for feedback on the manuscript and Dr. T.
  Piotrowski for invaluable support.\r\nWe thank the department of experimental medicine
  (AEM) in Copenhagen for expert fish\r\ncare. We gratefully acknowledge the DanStem
  Imaging Platform (University of Copenhagen)\r\nfor support and assistance in this
  work.\r\nThis work is supported by Novo Nordisk Foundation grant NNF17CC0027852
  (EAO);\r\nNordisk Foundation grant NNF19OC0058327 (EAO); Novo Nordisk Foundation
  grant\r\nNNF17OC0031204 (PRL); https://novonordiskfonden.dk/en/; Danish National\r\nResearch
  Foundation grant DNRF116 (EAO and AT); https://dg.dk/en/; John and Birthe Meyer\r\nFoundation
  (PRL) and European Research Council (ERC) under the EU Horizon 2020 research and
  Innovation Programme Grant Agreement No. 851288 (EH)."
article_number: e3002315
article_processing_charge: No
article_type: original
author:
- first_name: Iris A.
  full_name: Unterweger, Iris A.
  last_name: Unterweger
- first_name: Julie
  full_name: Klepstad, Julie
  last_name: Klepstad
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Pia R.
  full_name: Lundegaard, Pia R.
  last_name: Lundegaard
- first_name: Ala
  full_name: Trusina, Ala
  last_name: Trusina
- first_name: Elke A.
  full_name: Ober, Elke A.
  last_name: Ober
citation:
  ama: Unterweger IA, Klepstad J, Hannezo EB, Lundegaard PR, Trusina A, Ober EA. Lineage
    tracing identifies heterogeneous hepatoblast contribution to cell lineages and
    postembryonic organ growth dynamics. <i>PLoS Biology</i>. 2023;21(10). doi:<a
    href="https://doi.org/10.1371/journal.pbio.3002315">10.1371/journal.pbio.3002315</a>
  apa: Unterweger, I. A., Klepstad, J., Hannezo, E. B., Lundegaard, P. R., Trusina,
    A., &#38; Ober, E. A. (2023). Lineage tracing identifies heterogeneous hepatoblast
    contribution to cell lineages and postembryonic organ growth dynamics. <i>PLoS
    Biology</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pbio.3002315">https://doi.org/10.1371/journal.pbio.3002315</a>
  chicago: Unterweger, Iris A., Julie Klepstad, Edouard B Hannezo, Pia R. Lundegaard,
    Ala Trusina, and Elke A. Ober. “Lineage Tracing Identifies Heterogeneous Hepatoblast
    Contribution to Cell Lineages and Postembryonic Organ Growth Dynamics.” <i>PLoS
    Biology</i>. Public Library of Science, 2023. <a href="https://doi.org/10.1371/journal.pbio.3002315">https://doi.org/10.1371/journal.pbio.3002315</a>.
  ieee: I. A. Unterweger, J. Klepstad, E. B. Hannezo, P. R. Lundegaard, A. Trusina,
    and E. A. Ober, “Lineage tracing identifies heterogeneous hepatoblast contribution
    to cell lineages and postembryonic organ growth dynamics,” <i>PLoS Biology</i>,
    vol. 21, no. 10. Public Library of Science, 2023.
  ista: Unterweger IA, Klepstad J, Hannezo EB, Lundegaard PR, Trusina A, Ober EA.
    2023. Lineage tracing identifies heterogeneous hepatoblast contribution to cell
    lineages and postembryonic organ growth dynamics. PLoS Biology. 21(10), e3002315.
  mla: Unterweger, Iris A., et al. “Lineage Tracing Identifies Heterogeneous Hepatoblast
    Contribution to Cell Lineages and Postembryonic Organ Growth Dynamics.” <i>PLoS
    Biology</i>, vol. 21, no. 10, e3002315, Public Library of Science, 2023, doi:<a
    href="https://doi.org/10.1371/journal.pbio.3002315">10.1371/journal.pbio.3002315</a>.
  short: I.A. Unterweger, J. Klepstad, E.B. Hannezo, P.R. Lundegaard, A. Trusina,
    E.A. Ober, PLoS Biology 21 (2023).
date_created: 2023-10-15T22:01:10Z
date_published: 2023-10-04T00:00:00Z
date_updated: 2025-04-14T07:52:27Z
day: '04'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1371/journal.pbio.3002315
ec_funded: 1
file:
- access_level: open_access
  checksum: 40a2b11b41d70a0e5939f8a52b66e389
  content_type: application/pdf
  creator: dernst
  date_created: 2023-10-16T07:20:49Z
  date_updated: 2023-10-16T07:20:49Z
  file_id: '14431'
  file_name: 2023_PloSBiology_Unterweger.pdf
  file_size: 6193110
  relation: main_file
  success: 1
file_date_updated: 2023-10-16T07:20:49Z
fulldoi: https://doi.org/10.1371/journal.pbio.3002315
has_accepted_license: '1'
intvolume: '        21'
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: PLoS Biology
publication_identifier:
  eissn:
  - 1545-7885
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/JulieKlepstad/LiverDevelopment
scopus_import: '1'
status: public
title: Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages
  and postembryonic organ growth dynamics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2023'
...
---
_id: '14427'
abstract:
- lang: eng
  text: In the paper, we establish Squash Rigidity Theorem—the dynamical spectral
    rigidity for piecewise analytic Bunimovich squash-type stadia whose convex arcs
    are homothetic. We also establish Stadium Rigidity Theorem—the dynamical spectral
    rigidity for piecewise analytic Bunimovich stadia whose flat boundaries are a
    priori fixed. In addition, for smooth Bunimovich squash-type stadia we compute
    the Lyapunov exponents along the maximal period two orbit, as well as the value
    of the Peierls’ Barrier function from the maximal marked length spectrum associated
    to the rotation number 2n/4n+1.
acknowledgement: 'VK acknowledges a partial support by the NSF grant DMS-1402164 and
  ERC Grant #885707. Discussions with Martin Leguil and Jacopo De Simoi were very
  useful. JC visited the University of Maryland and thanks for the hospitality. Also,
  JC was partially supported by the National Key Research and Development Program
  of China (No.2022YFA1005802), the NSFC Grant 12001392 and NSF of Jiangsu BK20200850.
  H.-K. Zhang is partially supported by the National Science Foundation (DMS-2220211),
  as well as Simons Foundation Collaboration Grants for Mathematicians (706383).'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Jianyu
  full_name: Chen, Jianyu
  last_name: Chen
- first_name: Vadim
  full_name: Kaloshin, Vadim
  id: FE553552-CDE8-11E9-B324-C0EBE5697425
  last_name: Kaloshin
  orcid: 0000-0002-6051-2628
- first_name: Hong Kun
  full_name: Zhang, Hong Kun
  last_name: Zhang
citation:
  ama: Chen J, Kaloshin V, Zhang HK. Length spectrum rigidity for piecewise analytic
    Bunimovich billiards. <i>Communications in Mathematical Physics</i>. 2023;404:1-50.
    doi:<a href="https://doi.org/10.1007/s00220-023-04837-z">10.1007/s00220-023-04837-z</a>
  apa: Chen, J., Kaloshin, V., &#38; Zhang, H. K. (2023). Length spectrum rigidity
    for piecewise analytic Bunimovich billiards. <i>Communications in Mathematical
    Physics</i>. Springer Nature. <a href="https://doi.org/10.1007/s00220-023-04837-z">https://doi.org/10.1007/s00220-023-04837-z</a>
  chicago: Chen, Jianyu, Vadim Kaloshin, and Hong Kun Zhang. “Length Spectrum Rigidity
    for Piecewise Analytic Bunimovich Billiards.” <i>Communications in Mathematical
    Physics</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00220-023-04837-z">https://doi.org/10.1007/s00220-023-04837-z</a>.
  ieee: J. Chen, V. Kaloshin, and H. K. Zhang, “Length spectrum rigidity for piecewise
    analytic Bunimovich billiards,” <i>Communications in Mathematical Physics</i>,
    vol. 404. Springer Nature, pp. 1–50, 2023.
  ista: Chen J, Kaloshin V, Zhang HK. 2023. Length spectrum rigidity for piecewise
    analytic Bunimovich billiards. Communications in Mathematical Physics. 404, 1–50.
  mla: Chen, Jianyu, et al. “Length Spectrum Rigidity for Piecewise Analytic Bunimovich
    Billiards.” <i>Communications in Mathematical Physics</i>, vol. 404, Springer
    Nature, 2023, pp. 1–50, doi:<a href="https://doi.org/10.1007/s00220-023-04837-z">10.1007/s00220-023-04837-z</a>.
  short: J. Chen, V. Kaloshin, H.K. Zhang, Communications in Mathematical Physics
    404 (2023) 1–50.
corr_author: '1'
date_created: 2023-10-15T22:01:11Z
date_published: 2023-11-01T00:00:00Z
date_updated: 2025-04-14T07:53:45Z
day: '01'
department:
- _id: VaKa
doi: 10.1007/s00220-023-04837-z
ec_funded: 1
external_id:
  arxiv:
  - '1902.07330'
  isi:
  - '001073177200001'
fulldoi: https://doi.org/10.1007/s00220-023-04837-z
intvolume: '       404'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1902.07330
month: '11'
oa: 1
oa_version: Preprint
page: 1-50
project:
- _id: 9B8B92DE-BA93-11EA-9121-9846C619BF3A
  call_identifier: H2020
  grant_number: '885707'
  name: Spectral rigidity and integrability for billiards and geodesic flows
publication: Communications in Mathematical Physics
publication_identifier:
  eissn:
  - 1432-0916
  issn:
  - 0010-3616
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Length spectrum rigidity for piecewise analytic Bunimovich billiards
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 404
year: '2023'
...
