---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20404'
abstract:
- lang: eng
  text: Collagens are fundamental components of extracellular matrices, requiring
    precise intracellular post-translational modifications for proper function. Among
    the modifications, prolyl 4-hydroxylation is critical to stabilise the collagen
    triple helix. In humans, this reaction is mediated by collagen prolyl 4-hydroxylases
    (P4Hs). While humans possess three genes encoding these enzymes (P4H⍺s), Drosophila
    melanogaster harbour at least 26 candidates for collagen P4H⍺s despite its simple
    genome, and it is poorly understood which of them are actually working on collagen
    in the fly. In this study, we addressed this question by carrying out thorough
    bioinformatic and biochemical analyses. We demonstrate that among the 26 potential
    collagen P4H⍺s, PH4⍺EFB shares the highest homology with vertebrate collagen P4H⍺s.
    Furthermore, while collagen P4Hs and their substrates must exist in the same cells,
    our transcriptomic analyses at the tissue and single cell levels showed a global
    co-expression of PH4⍺EFB but not the other P4H⍺-related genes with the collagen
    IV genes. Moreover, expression of PH4⍺EFB during embryogenesis was found to precede
    that of collagen IV, presumably enabling efficient collagen modification by PH4⍺EFB.
    Finally, biochemical assays confirm that PH4⍺EFB binds collagen, supporting its
    direct role in collagen IV modification. Collectively, we identify PH4⍺EFB as
    the primary and potentially constitutive prolyl 4-hydroxylase responsible for
    collagen IV biosynthesis in Drosophila. Our findings highlight the remarkably
    simple nature of Drosophila collagen IV biosynthesis, which may serve as a blueprint
    for defining the minimal requirements for collagen engineering.
acknowledgement: "This project was supported by the All May See Foundation 7031,182
  to YI, the Louisiana Board of Regents Support Fund: Research Competitiveness Subprogram
  to MAT, Austrian science fund (FWF) as part of the SFB Meiosis consortium FWF SFB
  F88-10 to Beatriz Vicoso (supported ME), American Heart Association 16POST2726018
  and American Cancer Society 132,123-PF-18–025–01-CSM postdoctoral fellowships to
  ALZ, National Institutes of Health R01 GM136961 and R35 GM148485 to SH-B, and the
  Academy of Medical Sciences/the Wellcome Trust/ the Government Department of Business,
  Energy and Industrial Strategy/the British Heart Foundation/Diabetes UK Springboard
  Award SBF008\\1115 to YM. \r\nComputational analyses of single-nucleus transcriptome
  data were performed on the high performance computer (HPC) at Bournemouth University,
  the HPC at Institute of Science and Technology Austria, and the high-performance
  computational resources provided by the Louisiana Optical Network Infrastructure
  (http://www.loni.org). The authors are grateful to the researchers who published
  the transcriptome datasets [48,49,52,55] that became the essential bases for this
  study, to FlyBase for curating the datasets in an easily accessible format, and
  the Drosophila Genomics Resource Center (DGRC), supported by NIH grant 2P40OD010949,
  for providing the D17 cell line used in this research. The authors thank Kristian
  Koski (University of Oulu, Finland) for crucial advice on the domain structure of
  collagen P4H⍺s, and Ryusuke Niwa and Ryo Hoshino (University of Tsukuba, Japan)
  for helpful discussions on SP."
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Yoshihiro
  full_name: Ishikawa, Yoshihiro
  last_name: Ishikawa
- first_name: Melissa A
  full_name: Toups, Melissa A
  id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
  last_name: Toups
  orcid: 0000-0002-9752-7380
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
- first_name: Allison L.
  full_name: Zajac, Allison L.
  last_name: Zajac
- first_name: Sally
  full_name: Horne-Badovinac, Sally
  last_name: Horne-Badovinac
- first_name: Yutaka
  full_name: Matsubayashi, Yutaka
  last_name: Matsubayashi
citation:
  ama: Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi
    Y. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila
    collagen IV. <i>Matrix Biology</i>. 2025;141(11):101-113. doi:<a href="https://doi.org/10.1016/j.matbio.2025.09.002">10.1016/j.matbio.2025.09.002</a>
  apa: Ishikawa, Y., Toups, M. A., Elkrewi, M. N., Zajac, A. L., Horne-Badovinac,
    S., &#38; Matsubayashi, Y. (2025). Evidence for the major role of PH4⍺EFB in the
    prolyl 4-hydroxylation of Drosophila collagen IV. <i>Matrix Biology</i>. Springer
    Nature. <a href="https://doi.org/10.1016/j.matbio.2025.09.002">https://doi.org/10.1016/j.matbio.2025.09.002</a>
  chicago: Ishikawa, Yoshihiro, Melissa A Toups, Marwan N Elkrewi, Allison L. Zajac,
    Sally Horne-Badovinac, and Yutaka Matsubayashi. “Evidence for the Major Role of
    PH4⍺EFB in the Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>.
    Springer Nature, 2025. <a href="https://doi.org/10.1016/j.matbio.2025.09.002">https://doi.org/10.1016/j.matbio.2025.09.002</a>.
  ieee: Y. Ishikawa, M. A. Toups, M. N. Elkrewi, A. L. Zajac, S. Horne-Badovinac,
    and Y. Matsubayashi, “Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation
    of Drosophila collagen IV,” <i>Matrix Biology</i>, vol. 141, no. 11. Springer
    Nature, pp. 101–113, 2025.
  ista: Ishikawa Y, Toups MA, Elkrewi MN, Zajac AL, Horne-Badovinac S, Matsubayashi
    Y. 2025. Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation
    of Drosophila collagen IV. Matrix Biology. 141(11), 101–113.
  mla: Ishikawa, Yoshihiro, et al. “Evidence for the Major Role of PH4⍺EFB in the
    Prolyl 4-Hydroxylation of Drosophila Collagen IV.” <i>Matrix Biology</i>, vol.
    141, no. 11, Springer Nature, 2025, pp. 101–13, doi:<a href="https://doi.org/10.1016/j.matbio.2025.09.002">10.1016/j.matbio.2025.09.002</a>.
  short: Y. Ishikawa, M.A. Toups, M.N. Elkrewi, A.L. Zajac, S. Horne-Badovinac, Y.
    Matsubayashi, Matrix Biology 141 (2025) 101–113.
date_created: 2025-09-28T22:01:26Z
date_published: 2025-11-01T00:00:00Z
date_updated: 2026-01-05T13:09:08Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1016/j.matbio.2025.09.002
external_id:
  isi:
  - '001583892100002'
  pmid:
  - '40946811'
file:
- access_level: open_access
  checksum: 764257db41865d19daec1935788f72d7
  content_type: application/pdf
  creator: dernst
  date_created: 2026-01-05T13:09:01Z
  date_updated: 2026-01-05T13:09:01Z
  file_id: '20948'
  file_name: 2025_MatrixBiology_Ishikawa.pdf
  file_size: 5844254
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  success: 1
file_date_updated: 2026-01-05T13:09:01Z
has_accepted_license: '1'
intvolume: '       141'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 101-113
pmid: 1
project:
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publication: Matrix Biology
publication_identifier:
  eissn:
  - 1569-1802
  issn:
  - 0945-053X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evidence for the major role of PH4⍺EFB in the prolyl 4-hydroxylation of Drosophila
  collagen IV
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 141
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20405'
abstract:
- lang: eng
  text: Dielectric breakdown of physical vacuum (Schwinger effect) is the textbook
    demonstration of compatibility of Relativity and Quantum theory. Although observing
    this effect is still practically unachievable, its analogue generalizations have
    been shown to be more readily attainable. This paper demonstrates that a gapped
    Dirac semiconductor, methylammonium lead-bromide perovskite (MAPbBr3), exhibits
    analogue dynamic Schwinger effect. Tunneling ionization under deep subgap mid-infrared
    irradiation leads to intense photoluminescence in the visible range, in full agreement
    with quasi-adiabatic theory. In addition to revealing a gapped extended system
    suitable for studying the analogue Schwinger effect, this observation holds great
    potential for nonperturbative field sensing, i.e., sensing electric fields through
    nonperturbative light-matter interactions. First, this paper illustrates this
    by measuring the local deviation from the nominally cubic phase of a perovskite
    single crystal, which can be interpreted in terms of frozen-in fields. Next, it
    is shown that analogue dynamic Schwinger effect can be used for nonperturbative
    amplification of nonparametric upconversion process in perovskites driven simultaneously
    by multiple optical fields. This discovery demonstrates the potential for material
    response beyond perturbation theory in the tunneling regime, offering extremely
    sensitive light detection and amplification across an ultrabroad spectral range
    not accessible by conventional devices.
acknowledged_ssus:
- _id: EM-Fac
acknowledgement: A.G.V. thanks Peter Balling for useful discussions. This research
  was supported by the Scientific Service Units (SSU) of ISTA through resources provided
  by the Electron Microscopy Facility (EMF), and by the Werner Siemens Foundation
  (WSS) for financial support.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Dusan
  full_name: Lorenc, Dusan
  id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87
  last_name: Lorenc
- first_name: Artem
  full_name: Volosniev, Artem
  id: 37D278BC-F248-11E8-B48F-1D18A9856A87
  last_name: Volosniev
  orcid: 0000-0003-0393-5525
- first_name: Ayan A.
  full_name: Zhumekenov, Ayan A.
  last_name: Zhumekenov
- first_name: Seungho
  full_name: Lee, Seungho
  id: BB243B88-D767-11E9-B658-BC13E6697425
  last_name: Lee
  orcid: 0000-0002-6962-8598
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Osman M.
  full_name: Bakr, Osman M.
  last_name: Bakr
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Zhanybek
  full_name: Alpichshev, Zhanybek
  id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Alpichshev
  orcid: 0000-0002-7183-5203
citation:
  ama: Lorenc D, Volosniev A, Zhumekenov AA, et al. Observation of analogue dynamic
    Schwinger effect and non-perturbative light sensing in lead halide perovskites.
    <i>ACS Photonics</i>. 2025;12(9):5220-5230. doi:<a href="https://doi.org/10.1021/acsphotonics.5c01360">10.1021/acsphotonics.5c01360</a>
  apa: Lorenc, D., Volosniev, A., Zhumekenov, A. A., Lee, S., Ibáñez, M., Bakr, O.
    M., … Alpichshev, Z. (2025). Observation of analogue dynamic Schwinger effect
    and non-perturbative light sensing in lead halide perovskites. <i>ACS Photonics</i>.
    American Chemical Society. <a href="https://doi.org/10.1021/acsphotonics.5c01360">https://doi.org/10.1021/acsphotonics.5c01360</a>
  chicago: Lorenc, Dusan, Artem Volosniev, Ayan A. Zhumekenov, Seungho Lee, Maria
    Ibáñez, Osman M. Bakr, Mikhail Lemeshko, and Zhanybek Alpichshev. “Observation
    of Analogue Dynamic Schwinger Effect and Non-Perturbative Light Sensing in Lead
    Halide Perovskites.” <i>ACS Photonics</i>. American Chemical Society, 2025. <a
    href="https://doi.org/10.1021/acsphotonics.5c01360">https://doi.org/10.1021/acsphotonics.5c01360</a>.
  ieee: D. Lorenc <i>et al.</i>, “Observation of analogue dynamic Schwinger effect
    and non-perturbative light sensing in lead halide perovskites,” <i>ACS Photonics</i>,
    vol. 12, no. 9. American Chemical Society, pp. 5220–5230, 2025.
  ista: Lorenc D, Volosniev A, Zhumekenov AA, Lee S, Ibáñez M, Bakr OM, Lemeshko M,
    Alpichshev Z. 2025. Observation of analogue dynamic Schwinger effect and non-perturbative
    light sensing in lead halide perovskites. ACS Photonics. 12(9), 5220–5230.
  mla: Lorenc, Dusan, et al. “Observation of Analogue Dynamic Schwinger Effect and
    Non-Perturbative Light Sensing in Lead Halide Perovskites.” <i>ACS Photonics</i>,
    vol. 12, no. 9, American Chemical Society, 2025, pp. 5220–30, doi:<a href="https://doi.org/10.1021/acsphotonics.5c01360">10.1021/acsphotonics.5c01360</a>.
  short: D. Lorenc, A. Volosniev, A.A. Zhumekenov, S. Lee, M. Ibáñez, O.M. Bakr, M.
    Lemeshko, Z. Alpichshev, ACS Photonics 12 (2025) 5220–5230.
corr_author: '1'
date_created: 2025-09-28T22:01:26Z
date_published: 2025-08-11T00:00:00Z
date_updated: 2025-12-01T12:59:51Z
day: '11'
ddc:
- '540'
- '530'
department:
- _id: MaIb
- _id: MiLe
- _id: ZhAl
doi: 10.1021/acsphotonics.5c01360
external_id:
  arxiv:
  - '2406.05032'
  isi:
  - '001547359300001'
file:
- access_level: open_access
  checksum: d42476279287a9a2f8aeafaef032f4a7
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-20T11:02:21Z
  date_updated: 2025-10-20T11:02:21Z
  file_id: '20502'
  file_name: 2025_ACSPhotonics_Lorenc.pdf
  file_size: 6609950
  relation: main_file
  success: 1
file_date_updated: 2025-10-20T11:02:21Z
has_accepted_license: '1'
intvolume: '        12'
isi: 1
issue: '9'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 5220-5230
project:
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
publication: ACS Photonics
publication_identifier:
  eissn:
  - 2330-4022
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Observation of analogue dynamic Schwinger effect and non-perturbative light
  sensing in lead halide perovskites
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '20406'
abstract:
- lang: eng
  text: 'The origin of the rest-optical emission of compact, red, high-redshift sources
    known as little red dots (LRDs) poses a major puzzle. If interpreted as starlight,
    it would imply that LRDs constitute the densest stellar systems in the Universe.
    However, alternative models suggest active galactic nuclei (AGN) may instead power
    the rest-optical continuum. Here, we present JWST/NIRSpec, NIRCam, and MIRI observations
    from the RUBIES and PRIMER programs of The Cliff: a bright LRD at z = 3.55 with
    an exceptional Balmer break, twice as strong as that of any high-redshift source
    previously observed. The spectra also reveal broad hydrogen (Hα FWHM ∼ 1500 km s−1)
    and He I emission, but no significant metal lines. We demonstrate that massive
    evolved stellar populations cannot explain the observed spectrum, even when considering
    unusually steep and strong dust attenuation or reasonable variations in the initial
    mass function. Moreover, the formally best-fit stellar mass and compact size (M* ∼ 1010.5 M⊙, 
    re ∼ 40 pc) would imply densities at which near-monthly stellar collisions might
    lead to significant X-ray emission. We argue that the Balmer break, emission lines,
    and Hα absorption line are instead most plausibly explained by a black hole star
    (BH*) scenario, in which dense gas surrounds a powerful ionising source. In contrast
    to recently proposed BH* models of dust-reddened AGN, we show that spectral fits
    in the rest UV to near-infrared favour an intrinsically redder continuum over
    strong dust reddening. This may point to a super-Eddington accreting massive black
    hole or, possibly, the presence of (super)massive stars in a nuclear star cluster.
    The Cliff is the clearest evidence to date that at least some LRDs are not ultra-dense
    massive galaxies, and are instead powered by a central ionising source embedded
    in dense, absorbing gas.'
acknowledgement: 'We thank the PRIMER team for making their imaging data publicly
  available immediately. We thank Jaime Villaseñor and Friedrich Röpke for helpful
  discussions. This work is based on observations made with the NASA/ESA/CSA James
  Webb Space Telescope. The data were obtained from the Mikulski Archive for Space
  Telescopes at the Space Telescope Science Institute, which is operated by the Association
  of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127
  for JWST. These observations are associated with programs #1837 and #4233. Support
  for program #4233 was provided by NASA through a grant from the Space Telescope
  Science Institute, which is operated by the Association of Universities for Research
  in Astronomy, Inc., under NASA contract NAS 5-03127. REH acknowledges support by
  the German Aerospace Center (DLR) and the Federal Ministry for Economic Affairs
  and Energy (BMWi) through program 50OR2403 ‘RUBIES’. This research was supported
  by the International Space Science Institute (ISSI) in Bern, through ISSI International
  Team project #562. The Cosmic Dawn Center is funded by the Danish National Research
  Foundation (DNRF) under grant #140. This work has received funding from the Swiss
  State Secretariat for Education, Research and Innovation (SERI) under contract number
  MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through
  project grant 200020_207349. Support for this work for RPN was provided by NASA
  through the NASA Hubble Fellowship grant HST-HF2-51515.001-A awarded by the Space
  Telescope Science Institute, which is operated by the Association of Universities
  for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. TBM was
  supported by a CIERA fellowship. Open Access funding provided by Max Planck Society.'
article_number: A168
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Anna
  full_name: De Graaff, Anna
  last_name: De Graaff
- first_name: Hans Walter
  full_name: Rix, Hans Walter
  last_name: Rix
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Ivo
  full_name: Labbé, Ivo
  last_name: Labbé
- first_name: Bingjie
  full_name: Wang, Bingjie
  last_name: Wang
- first_name: Joel
  full_name: Leja, Joel
  last_name: Leja
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Harley
  full_name: Katz, Harley
  last_name: Katz
- first_name: Jenny E.
  full_name: Greene, Jenny E.
  last_name: Greene
- first_name: Raphael E.
  full_name: Hviding, Raphael E.
  last_name: Hviding
- first_name: Josephine
  full_name: Baggen, Josephine
  last_name: Baggen
- first_name: Rachel
  full_name: Bezanson, Rachel
  last_name: Bezanson
- first_name: Leindert A.
  full_name: Boogaard, Leindert A.
  last_name: Boogaard
- first_name: Gabriel
  full_name: Brammer, Gabriel
  last_name: Brammer
- first_name: Pratika
  full_name: Dayal, Pratika
  last_name: Dayal
- first_name: Pieter
  full_name: Van Dokkum, Pieter
  last_name: Van Dokkum
- first_name: Andy D.
  full_name: Goulding, Andy D.
  last_name: Goulding
- first_name: Michaela
  full_name: Hirschmann, Michaela
  last_name: Hirschmann
- first_name: Michael V.
  full_name: Maseda, Michael V.
  last_name: Maseda
- first_name: Ian
  full_name: Mcconachie, Ian
  last_name: Mcconachie
- first_name: Tim B.
  full_name: Miller, Tim B.
  last_name: Miller
- first_name: Erica
  full_name: Nelson, Erica
  last_name: Nelson
- first_name: Pascal A.
  full_name: Oesch, Pascal A.
  last_name: Oesch
- first_name: David J.
  full_name: Setton, David J.
  last_name: Setton
- first_name: Irene
  full_name: Shivaei, Irene
  last_name: Shivaei
- first_name: Andrea
  full_name: Weibel, Andrea
  last_name: Weibel
- first_name: Katherine E.
  full_name: Whitaker, Katherine E.
  last_name: Whitaker
- first_name: Christina C.
  full_name: Williams, Christina C.
  last_name: Williams
citation:
  ama: 'De Graaff A, Rix HW, Naidu RP, et al. A remarkable ruby: Absorption in dense
    gas, rather than evolved stars, drives the extreme Balmer break of a little red
    dot at z = 3.5. <i>Astronomy &#38; Astrophysics</i>. 2025;701. doi:<a href="https://doi.org/10.1051/0004-6361/202554681">10.1051/0004-6361/202554681</a>'
  apa: 'De Graaff, A., Rix, H. W., Naidu, R. P., Labbé, I., Wang, B., Leja, J., …
    Williams, C. C. (2025). A remarkable ruby: Absorption in dense gas, rather than
    evolved stars, drives the extreme Balmer break of a little red dot at z = 3.5.
    <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202554681">https://doi.org/10.1051/0004-6361/202554681</a>'
  chicago: 'De Graaff, Anna, Hans Walter Rix, Rohan P. Naidu, Ivo Labbé, Bingjie Wang,
    Joel Leja, Jorryt J Matthee, et al. “A Remarkable Ruby: Absorption in Dense Gas,
    Rather than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot
    at z = 3.5.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025. <a href="https://doi.org/10.1051/0004-6361/202554681">https://doi.org/10.1051/0004-6361/202554681</a>.'
  ieee: 'A. De Graaff <i>et al.</i>, “A remarkable ruby: Absorption in dense gas,
    rather than evolved stars, drives the extreme Balmer break of a little red dot
    at z = 3.5,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.'
  ista: 'De Graaff A, Rix HW, Naidu RP, Labbé I, Wang B, Leja J, Matthee JJ, Katz
    H, Greene JE, Hviding RE, Baggen J, Bezanson R, Boogaard LA, Brammer G, Dayal
    P, Van Dokkum P, Goulding AD, Hirschmann M, Maseda MV, Mcconachie I, Miller TB,
    Nelson E, Oesch PA, Setton DJ, Shivaei I, Weibel A, Whitaker KE, Williams CC.
    2025. A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives
    the extreme Balmer break of a little red dot at z = 3.5. Astronomy &#38; Astrophysics.
    701, A168.'
  mla: 'De Graaff, Anna, et al. “A Remarkable Ruby: Absorption in Dense Gas, Rather
    than Evolved Stars, Drives the Extreme Balmer Break of a Little Red Dot at z =
    3.5.” <i>Astronomy &#38; Astrophysics</i>, vol. 701, A168, EDP Sciences, 2025,
    doi:<a href="https://doi.org/10.1051/0004-6361/202554681">10.1051/0004-6361/202554681</a>.'
  short: A. De Graaff, H.W. Rix, R.P. Naidu, I. Labbé, B. Wang, J. Leja, J.J. Matthee,
    H. Katz, J.E. Greene, R.E. Hviding, J. Baggen, R. Bezanson, L.A. Boogaard, G.
    Brammer, P. Dayal, P. Van Dokkum, A.D. Goulding, M. Hirschmann, M.V. Maseda, I.
    Mcconachie, T.B. Miller, E. Nelson, P.A. Oesch, D.J. Setton, I. Shivaei, A. Weibel,
    K.E. Whitaker, C.C. Williams, Astronomy &#38; Astrophysics 701 (2025).
date_created: 2025-09-28T22:01:27Z
date_published: 2025-09-01T00:00:00Z
date_updated: 2026-02-16T12:13:12Z
day: '01'
ddc:
- '520'
department:
- _id: JoMa
doi: 10.1051/0004-6361/202554681
external_id:
  arxiv:
  - '2503.16600'
  isi:
  - '001570450900004'
file:
- access_level: open_access
  checksum: cf93d635121dbf4865fd080c517927d0
  content_type: application/pdf
  creator: dernst
  date_created: 2025-09-29T06:59:14Z
  date_updated: 2025-09-29T06:59:14Z
  file_id: '20409'
  file_name: 2025_AstronomyAstrophysics_deGraaff2.pdf
  file_size: 1218479
  relation: main_file
  success: 1
file_date_updated: 2025-09-29T06:59:14Z
has_accepted_license: '1'
intvolume: '       701'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A remarkable ruby: Absorption in dense gas, rather than evolved stars, drives
  the extreme Balmer break of a little red dot at z = 3.5'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 701
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20407'
abstract:
- lang: eng
  text: We suggest a new algorithm to estimate representations of compact Lie groups
    from finite samples of their orbits. Different from other reported techniques,
    our method allows the retrieval of the precise representation type as a direct
    sum of irreducible representations. Moreover, the knowledge of the representation
    type permits the reconstruction of its orbit, which is useful for identifying
    the Lie group that generates the action, from a finite list of candidates. Our
    algorithm is general for any compact Lie group, but only instantiations for SO(2),
    T^d, SU(2), and SO(3) are considered. Theoretical guarantees of robustness in
    terms of Hausdorff and Wasserstein distances are derived. Our tools are drawn
    from geometric measure theory, computational geometry, and optimization on matrix
    manifolds. The algorithm is tested for synthetic data up to dimension 32, as well
    as real-life applications in image analysis, harmonic analysis, density estimation,
    equivariant neural networks, chemical conformational spaces, and classical mechanics
    systems, achieving very accurate results.
acknowledgement: The original work behind this article was developed for HE’s master’s
  thesis, supervised by RT. We are mostly in debt to César Camacho, who was HE’s co-advisor,
  as well as the members of the thesis jury, Clément Maria, Eduardo Mendes, and Jameson
  Cahill, not only for agreeing to evaluate the original work but also for many valuable
  inputs. Finally, we are indebted to the anonymous reviewers for their important
  feedback and suggestions. Open access funding provided by Institute of Science and
  Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Henrique
  full_name: Ennes, Henrique
  last_name: Ennes
- first_name: Raphaël
  full_name: Tinarrage, Raphaël
  id: 40ebcc9d-905f-11ef-bf0a-dc475da8a04e
  last_name: Tinarrage
  orcid: 0000-0002-1404-1095
citation:
  ama: 'Ennes H, Tinarrage R. LieDetect: Detection of representation orbits of compact
    Lie groups from point clouds. <i>Foundations of Computational Mathematics</i>.
    2025. doi:<a href="https://doi.org/10.1007/s10208-025-09728-4">10.1007/s10208-025-09728-4</a>'
  apa: 'Ennes, H., &#38; Tinarrage, R. (2025). LieDetect: Detection of representation
    orbits of compact Lie groups from point clouds. <i>Foundations of Computational
    Mathematics</i>. Springer Nature. <a href="https://doi.org/10.1007/s10208-025-09728-4">https://doi.org/10.1007/s10208-025-09728-4</a>'
  chicago: 'Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation
    Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational
    Mathematics</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s10208-025-09728-4">https://doi.org/10.1007/s10208-025-09728-4</a>.'
  ieee: 'H. Ennes and R. Tinarrage, “LieDetect: Detection of representation orbits
    of compact Lie groups from point clouds,” <i>Foundations of Computational Mathematics</i>.
    Springer Nature, 2025.'
  ista: 'Ennes H, Tinarrage R. 2025. LieDetect: Detection of representation orbits
    of compact Lie groups from point clouds. Foundations of Computational Mathematics.'
  mla: 'Ennes, Henrique, and Raphaël Tinarrage. “LieDetect: Detection of Representation
    Orbits of Compact Lie Groups from Point Clouds.” <i>Foundations of Computational
    Mathematics</i>, Springer Nature, 2025, doi:<a href="https://doi.org/10.1007/s10208-025-09728-4">10.1007/s10208-025-09728-4</a>.'
  short: H. Ennes, R. Tinarrage, Foundations of Computational Mathematics (2025).
corr_author: '1'
date_created: 2025-09-28T22:01:27Z
date_published: 2025-09-15T00:00:00Z
date_updated: 2025-09-30T14:44:53Z
day: '15'
department:
- _id: UlWa
doi: 10.1007/s10208-025-09728-4
external_id:
  arxiv:
  - '2309.03086'
  isi:
  - '001571197200001'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s10208-025-09728-4
month: '09'
oa: 1
oa_version: Published Version
publication: Foundations of Computational Mathematics
publication_identifier:
  eissn:
  - 1615-3383
  issn:
  - 1615-3375
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'LieDetect: Detection of representation orbits of compact Lie groups from point
  clouds'
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20423'
abstract:
- lang: eng
  text: "For any d  2, we prove that there exists an integer n0(d) such that there
    exists an n × n\r\nmagic square of dth powers for all n  n0(d). In particular,
    we establish the existence of\r\nan n × n magic square of squares for all n  4,
    which settles a conjecture of\r\nVárilly-Alvarado. All previous approaches had
    been based on constructive methods and\r\nthe existence of n × n magic squares
    of dth powers had only been known for sparse\r\nvalues of n. We prove our result
    by the Hardy-Littlewood circle method, which in this\r\nsetting essentially reduces
    the problem to finding a sufficient number of disjoint linearly\r\nindependent
    subsets of the columns of the coefficient matrix of the equations defining\r\nmagic
    squares. We prove an optimal (up to a constant) lower bound for this quantity."
acknowledgement: "The authors are grateful to Tim Browning for his constant encouragement
  and enthusiasm, Jörg Brüdern for very helpful discussion regarding his paper [1]
  and Diyuan Wu for turning the proof of Theorem 2.4 in the original version into
  an algorithm and running the computation for us, for which the results are available
  in the appendix of the original version. They would also like to thank Christian
  Boyer for maintaining his website [4] which contains a comprehensive list of various
  magic squares discovered, Brady Haran and Tony Várilly-Alvarado for their public
  engagement activity of mathematics and magic squares of squares (A YouTube video
  “Magic Squares of Squares (are PROBABLY impossible)” of the Numberphile channel
  by Brady Haran, in which Tony Várilly-Alvarado appears as a guest speaker: https://www.youtube.com/watch?v=Kdsj84UdeYg.),
  and all the magic squares enthusiasts who have contributed to [4] which made this
  paper possible. Finally, the authors would like to thank the anonymous referees
  for their helpful comments, Daniel Flores for his work [11] which inspired them
  to optimise the proof of Theorem 2.4 and Trevor Wooley for very helpful discussion
  regarding recent developments in Waring’s problem and his comments on the original
  version of this paper.\r\nOpen access funding provided by Institute of Science and
  Technology (IST Austria). NR was supported by FWF project ESP 441-NBL while SY by
  a FWF grant (DOI 10.55776/P32428)."
article_number: '91'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Nick
  full_name: Rome, Nick
  last_name: Rome
- first_name: Shuntaro
  full_name: Yamagishi, Shuntaro
  id: 0c3fbc5c-f7a6-11ec-8d70-9485e75b416b
  last_name: Yamagishi
citation:
  ama: Rome N, Yamagishi S. On the existence of magic squares of powers. <i>Research
    in Number Theory</i>. 2025;11(4). doi:<a href="https://doi.org/10.1007/s40993-025-00671-5">10.1007/s40993-025-00671-5</a>
  apa: Rome, N., &#38; Yamagishi, S. (2025). On the existence of magic squares of
    powers. <i>Research in Number Theory</i>. Springer Nature. <a href="https://doi.org/10.1007/s40993-025-00671-5">https://doi.org/10.1007/s40993-025-00671-5</a>
  chicago: Rome, Nick, and Shuntaro Yamagishi. “On the Existence of Magic Squares
    of Powers.” <i>Research in Number Theory</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s40993-025-00671-5">https://doi.org/10.1007/s40993-025-00671-5</a>.
  ieee: N. Rome and S. Yamagishi, “On the existence of magic squares of powers,” <i>Research
    in Number Theory</i>, vol. 11, no. 4. Springer Nature, 2025.
  ista: Rome N, Yamagishi S. 2025. On the existence of magic squares of powers. Research
    in Number Theory. 11(4), 91.
  mla: Rome, Nick, and Shuntaro Yamagishi. “On the Existence of Magic Squares of Powers.”
    <i>Research in Number Theory</i>, vol. 11, no. 4, 91, Springer Nature, 2025, doi:<a
    href="https://doi.org/10.1007/s40993-025-00671-5">10.1007/s40993-025-00671-5</a>.
  short: N. Rome, S. Yamagishi, Research in Number Theory 11 (2025).
corr_author: '1'
date_created: 2025-10-05T22:01:34Z
date_published: 2025-09-23T00:00:00Z
date_updated: 2025-10-13T12:30:40Z
day: '23'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1007/s40993-025-00671-5
external_id:
  arxiv:
  - '2406.09364'
file:
- access_level: open_access
  checksum: d41fbdc0cfc1fbceb519eb49b20a3ec2
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T11:28:49Z
  date_updated: 2025-10-13T11:28:49Z
  file_id: '20463'
  file_name: 2025_ResearchNumberTheory_Rome.pdf
  file_size: 428531
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T11:28:49Z
has_accepted_license: '1'
intvolume: '        11'
issue: '4'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 26AEDAB2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P32428
  name: New frontiers of the Manin conjecture
publication: Research in Number Theory
publication_identifier:
  eissn:
  - 2363-9555
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the existence of magic squares of powers
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
_id: '20424'
abstract:
- lang: eng
  text: Homeostasis relies on a precise balance of fate choices between renewal and
    differentiation. Although progress has been done to characterize the dynamics
    of single-cell fate choices, their underlying mechanistic basis often remains
    unclear. Concentrating on skin epidermis as a paradigm for multilayered tissues
    with complex fate choices, we develop a 3D vertex-based model with proliferation
    in the basal layer, showing that mechanical competition for space naturally gives
    rise to homeostasis and neutral drift dynamics that are seen experimentally. We
    then explore the effect of introducing mechanical heterogeneities between cellular
    subpopulations. We uncover that relatively small tension heterogeneities, reflected
    by distinct morphological changes in single-cell shapes, can be sufficient to
    heavily tilt cellular dynamics towards exponential growth. We thus derive a master
    relationship between cell shape and long-term clonal dynamics, which we validated
    during basal cell carcinoma initiation in mouse epidermis. Altogether, we propose
    a theoretical framework to link mechanical forces, quantitative cellular morphologies
    and cellular fate outcomes in complex tissues.
acknowledged_ssus:
- _id: Bio
acknowledgement: We thank Alois Schlögl, Paula Sanematsu, Susana Moreno Flores, Bernat
  Corominas-Murtra, Stefania Tavano, Gayathri Singharaju, and Hannezo group members
  for helpful discussions, the Bioimaging facility at ISTA, as well as Matthias Merkel
  and Lisa Manning for sharing the 3D Voronoi code. We also thank the Champalimaud
  animal facility, Anna Pezzarossa and the Champalimaud ABBE platform for the help
  with microscopy and image processing. This work was supported by EMBO (ALTF 522-2021),
  a Fundação para a Ciência e Tecnologia grant to A.S.D. (PTDC/MED-ONC/5553/2020),
  as well as the European Research Council (grant 851288 to EH). A.S.D., S.C., and
  R.M.S. are supported by QuantOCancer Project Horizon European Union’s Horizon 2020
  program (grant agreement No 810653).
article_number: '8440'
article_processing_charge: Yes
article_type: original
author:
- first_name: Preeti
  full_name: Sahu, Preeti
  id: 55BA52EE-A185-11EA-88FD-18AD3DDC885E
  last_name: Sahu
- first_name: Sara
  full_name: Monteiro-Ferreira, Sara
  last_name: Monteiro-Ferreira
- first_name: Sara
  full_name: Canato, Sara
  last_name: Canato
- first_name: Raquel Maia
  full_name: Soares, Raquel Maia
  last_name: Soares
- first_name: Adriana
  full_name: Sánchez-Danés, Adriana
  last_name: Sánchez-Danés
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
citation:
  ama: Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo
    EB. Mechanical control of cell fate decisions in the skin epidermis. <i>Nature
    Communications</i>. 2025;16. doi:<a href="https://doi.org/10.1038/s41467-025-62882-9">10.1038/s41467-025-62882-9</a>
  apa: Sahu, P., Monteiro-Ferreira, S., Canato, S., Soares, R. M., Sánchez-Danés,
    A., &#38; Hannezo, E. B. (2025). Mechanical control of cell fate decisions in
    the skin epidermis. <i>Nature Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-025-62882-9">https://doi.org/10.1038/s41467-025-62882-9</a>
  chicago: Sahu, Preeti, Sara Monteiro-Ferreira, Sara Canato, Raquel Maia Soares,
    Adriana Sánchez-Danés, and Edouard B Hannezo. “Mechanical Control of Cell Fate
    Decisions in the Skin Epidermis.” <i>Nature Communications</i>. Springer Nature,
    2025. <a href="https://doi.org/10.1038/s41467-025-62882-9">https://doi.org/10.1038/s41467-025-62882-9</a>.
  ieee: P. Sahu, S. Monteiro-Ferreira, S. Canato, R. M. Soares, A. Sánchez-Danés,
    and E. B. Hannezo, “Mechanical control of cell fate decisions in the skin epidermis,”
    <i>Nature Communications</i>, vol. 16. Springer Nature, 2025.
  ista: Sahu P, Monteiro-Ferreira S, Canato S, Soares RM, Sánchez-Danés A, Hannezo
    EB. 2025. Mechanical control of cell fate decisions in the skin epidermis. Nature
    Communications. 16, 8440.
  mla: Sahu, Preeti, et al. “Mechanical Control of Cell Fate Decisions in the Skin
    Epidermis.” <i>Nature Communications</i>, vol. 16, 8440, Springer Nature, 2025,
    doi:<a href="https://doi.org/10.1038/s41467-025-62882-9">10.1038/s41467-025-62882-9</a>.
  short: P. Sahu, S. Monteiro-Ferreira, S. Canato, R.M. Soares, A. Sánchez-Danés,
    E.B. Hannezo, Nature Communications 16 (2025).
corr_author: '1'
date_created: 2025-10-05T22:01:34Z
date_published: 2025-09-26T00:00:00Z
date_updated: 2025-12-01T12:54:59Z
day: '26'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1038/s41467-025-62882-9
ec_funded: 1
external_id:
  isi:
  - '001582555200011'
  pmid:
  - '41006218'
file:
- access_level: open_access
  checksum: d1656576883b23902545328e2d640234
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T12:37:04Z
  date_updated: 2025-10-13T12:37:04Z
  file_id: '20464'
  file_name: 2025_NatureComm_Sahu.pdf
  file_size: 2816813
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T12:37:04Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 628f3fb1-2b32-11ec-9570-83ce778803f7
  grant_number: ALTF 522-2021
  name: Biomechanics of stem cell fate determination
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanical control of cell fate decisions in the skin epidermis
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20425'
abstract:
- lang: eng
  text: Ultraviolet (UV) radiation from accreting black holes ionizes the intergalactic
    gas around early quasars, carving out highly ionized bubbles in their surroundings.
    Any changes in a quasar’s luminosity are therefore predicted to produce outward-propagating
    ionization gradients, affecting the Lyα absorption opacity near the quasar’s systemic
    redshift. This “proximity effect” is well-documented in rest-UV quasar spectra
    but only provides a one-dimensional probe along our line of sight. Here we present
    deep spectroscopic observations with the James Webb Space Telescope (JWST) of
    galaxies in the background of a superluminous quasar at zQSO ≈ 6.3, which reveal
    the quasar’s “light echo” with Lyα tomography in the transverse direction. This
    transverse proximity effect is detected for the first time toward multiple galaxy
    sightlines, allowing us to map the extent and geometry of the quasar’s ionization
    cone. We obtain constraints on the orientation and inclination of the cone, as
    well as an upper limit on the obscured solid angle fraction of fobsc < 91%. Additionally,
    we find a timescale of the quasar’s UV radiation of tqso = 10^5.6+0.1-0.3 yr,
    which is significantly shorter than would be required to build up the central
    supermassive black hole (SMBH) with conventional growth models, but is consistent
    with independent measurements of the quasars’ duty cycle. Our inferred obscured
    fraction disfavors a scenario where short quasar lifetimes can be explained exclusively
    by geometric obscuration, and instead supports the idea that radiatively inefficient
    accretion or growth in initially heavily enshrouded cocoons plays a pivotal role
    in early SMBH growth. Our results pave the way for novel studies of quasars’ ionizing
    geometries and radiative histories at early cosmic times.
acknowledgement: "This work is based on observations made with the NASA/ESA/CSA James
  Webb Space Telescope. The data were obtained from the Mikulski Archive for Space
  Telescopes at the Space Telescope Science Institute, which is operated by the Association
  of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127
  for JWST. These observations are associated with programs #1243 and #4713.\r\n\r\nAll
  of the data presented in this Letter were obtained from the Mikulski Archive for
  Space Telescopes (MAST) at the Space Telescope Science Institute. The specific observations
  analyzed can be accessed via doi:10.17909/w7hm-qb39.\r\nJ.M. is supported by the
  European Union (ERC, AGENTS, 101076224)."
article_number: L40
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Anna Christina
  full_name: Eilers, Anna Christina
  last_name: Eilers
- first_name: Minghao
  full_name: Yue, Minghao
  last_name: Yue
- first_name: Jorryt J
  full_name: Matthee, Jorryt J
  id: 7439a258-f3c0-11ec-9501-9df22fe06720
  last_name: Matthee
  orcid: 0000-0003-2871-127X
- first_name: Joseph F.
  full_name: Hennawi, Joseph F.
  last_name: Hennawi
- first_name: Frederick B.
  full_name: Davies, Frederick B.
  last_name: Davies
- first_name: Robert A.
  full_name: Simcoe, Robert A.
  last_name: Simcoe
- first_name: Richard
  full_name: Teague, Richard
  last_name: Teague
- first_name: Rongmon
  full_name: Bordoloi, Rongmon
  last_name: Bordoloi
- first_name: Gabriel
  full_name: Brammer, Gabriel
  last_name: Brammer
- first_name: Yi
  full_name: Kang, Yi
  last_name: Kang
- first_name: Daichi
  full_name: Kashino, Daichi
  last_name: Kashino
- first_name: Ruari
  full_name: Mackenzie, Ruari
  last_name: Mackenzie
- first_name: Rohan P.
  full_name: Naidu, Rohan P.
  last_name: Naidu
- first_name: Benjamín
  full_name: Navarrete, Benjamín
  id: aa14a535-50c9-11ef-b52e-e0c373d10148
  last_name: Navarrete
citation:
  ama: Eilers AC, Yue M, Matthee JJ, et al. The light echo of a high-redshift quasar
    mapped with Lyα tomography. <i>The Astrophysical Journal Letters</i>. 2025;991(2).
    doi:<a href="https://doi.org/10.3847/2041-8213/ae057a">10.3847/2041-8213/ae057a</a>
  apa: Eilers, A. C., Yue, M., Matthee, J. J., Hennawi, J. F., Davies, F. B., Simcoe,
    R. A., … Navarrete, B. (2025). The light echo of a high-redshift quasar mapped
    with Lyα tomography. <i>The Astrophysical Journal Letters</i>. IOP Publishing.
    <a href="https://doi.org/10.3847/2041-8213/ae057a">https://doi.org/10.3847/2041-8213/ae057a</a>
  chicago: Eilers, Anna Christina, Minghao Yue, Jorryt J Matthee, Joseph F. Hennawi,
    Frederick B. Davies, Robert A. Simcoe, Richard Teague, et al. “The Light Echo
    of a High-Redshift Quasar Mapped with Lyα Tomography.” <i>The Astrophysical Journal
    Letters</i>. IOP Publishing, 2025. <a href="https://doi.org/10.3847/2041-8213/ae057a">https://doi.org/10.3847/2041-8213/ae057a</a>.
  ieee: A. C. Eilers <i>et al.</i>, “The light echo of a high-redshift quasar mapped
    with Lyα tomography,” <i>The Astrophysical Journal Letters</i>, vol. 991, no.
    2. IOP Publishing, 2025.
  ista: Eilers AC, Yue M, Matthee JJ, Hennawi JF, Davies FB, Simcoe RA, Teague R,
    Bordoloi R, Brammer G, Kang Y, Kashino D, Mackenzie R, Naidu RP, Navarrete B.
    2025. The light echo of a high-redshift quasar mapped with Lyα tomography. The
    Astrophysical Journal Letters. 991(2), L40.
  mla: Eilers, Anna Christina, et al. “The Light Echo of a High-Redshift Quasar Mapped
    with Lyα Tomography.” <i>The Astrophysical Journal Letters</i>, vol. 991, no.
    2, L40, IOP Publishing, 2025, doi:<a href="https://doi.org/10.3847/2041-8213/ae057a">10.3847/2041-8213/ae057a</a>.
  short: A.C. Eilers, M. Yue, J.J. Matthee, J.F. Hennawi, F.B. Davies, R.A. Simcoe,
    R. Teague, R. Bordoloi, G. Brammer, Y. Kang, D. Kashino, R. Mackenzie, R.P. Naidu,
    B. Navarrete, The Astrophysical Journal Letters 991 (2025).
date_created: 2025-10-05T22:01:35Z
date_published: 2025-09-25T00:00:00Z
date_updated: 2026-02-16T12:44:42Z
day: '25'
ddc:
- '520'
department:
- _id: JoMa
- _id: GradSch
doi: 10.3847/2041-8213/ae057a
external_id:
  arxiv:
  - '2509.05417'
  isi:
  - '001581023000001'
file:
- access_level: open_access
  checksum: 3cb8099b9a915755164e5675b33f8a03
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T09:25:12Z
  date_updated: 2025-10-13T09:25:12Z
  file_id: '20461'
  file_name: 2025_AstrophysicalJour_Eilers.pdf
  file_size: 23585591
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T09:25:12Z
has_accepted_license: '1'
intvolume: '       991'
isi: 1
issue: '2'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: bd9b2118-d553-11ed-ba76-db24564edfea
  grant_number: '101076224'
  name: Young galaxies as tracers and agents of cosmic reionization
publication: The Astrophysical Journal Letters
publication_identifier:
  eissn:
  - 2041-8213
  issn:
  - 2041-8205
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: The light echo of a high-redshift quasar mapped with Lyα tomography
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 991
year: '2025'
...
---
OA_type: closed access
_id: '20426'
abstract:
- lang: eng
  text: SnTe has attracted significant research interest as a lead-free alternative
    to PbTe; however, its intrinsically high hole concentration results in an undesirably
    low Seebeck coefficient and elevated electronic thermal conductivity, thus significantly
    limiting its thermoelectric (TE) performance. Herein, we present a cost-effective,
    binary thiol-amine-mediated colloidal synthesis method to synthesize Bi-doped
    SnTe nanoparticles, eliminating the use of tri-n-octylphosphine-based precursors.
    The introduction of an electron-rich Bi dopant reduces the hole concentration
    and increases the Seebeck coefficient. Furthermore, post-synthetic surface treatment
    with chalcogenidocadmate complexes promotes atomic interdiffusion during annealing
    and consolidation, leading to compositional redistribution and modulation of the
    electronic band structure. Density functional theory (DFT) calculations reveal
    that co-modification via Bi doping and CdSe-derived chalcogen incorporation reduces
    the energy offset at the valence band maxima from 0.30 eV to 0.10 eV, thereby
    enhancing valence band degeneracy. The synergistic structural and electronic band
    structure modulations produce an SnTe-based material with a record high power
    factor of 2.1 mW m–1 K–2 at 900 K, a maximum TE figure of merit (zT) of 1.2, and
    a promising theoretical conversion efficiency of 8.3%. This study reports a versatile
    and scalable colloidal synthesis strategy that integrates hierarchical structural
    modulation with electronic band engineering, offering a synergistic route to significantly
    enhance the TE performance.
acknowledgement: Y.L. acknowledges funding from the National Natural Science Foundation
  of China (NSFC) (Grant No. 22209034), the Innovation and Entrepreneurship Project
  of Overseas Returnees in Anhui Province (Grant No. 2022LCX002), and the Fundamental
  Research Funds for the Central Universities (JZ2024HGTB0239). K.H.L. acknowledges
  financial support from the National Natural Science Foundation of China (NSFC) (Grant
  No. 22208293) and the National Foreign Expert Project (Y20240175). Y.Z. acknowledges
  funding from the NSFC (Grant No. 52502313) and Wenzhou Basic Scientific Research
  Project (Grant No. G20240034). Q.W. acknowledges the financial support from the
  NSFC (Grant No. 22208292) and the “Pioneer” and “Leading Goose” R&D Program of Zhejiang
  (2025C04021). K.H.L. and Q.W. also acknowledge the Research Funds of the Institute
  of Zhejiang University-Quzhou (Nos. IZQ2022RCZX101, IZQ2021RCZX003, and IZQ2021RCZX002).
  M.H. acknowledges the funding from the Australian Research Council and the iLAuNCH
  Trailblazer, Department of Education, Australia. M.H. acknowledges the computational
  support from the National Computational Infrastructure (NCI), Australia and Pawsey
  Supercomputing Centre, Australia. The author also thanks Dr. Lijian Huang and Mr.
  Mincheng Yu at the Institute of Zhejiang University for the swift technical assistance
  during XPS characterization and quantification.
article_processing_charge: No
article_type: original
author:
- first_name: Weite
  full_name: Meng, Weite
  last_name: Meng
- first_name: Lixiang
  full_name: Xu, Lixiang
  last_name: Xu
- first_name: Shaoqing
  full_name: Lu, Shaoqing
  last_name: Lu
- first_name: Mingquan
  full_name: Li, Mingquan
  last_name: Li
- first_name: Mengyao
  full_name: Li, Mengyao
  last_name: Li
- first_name: Yu
  full_name: Zhang, Yu
  last_name: Zhang
- first_name: Qingyue
  full_name: Wang, Qingyue
  last_name: Wang
- first_name: Wen Jun
  full_name: Wang, Wen Jun
  last_name: Wang
- first_name: Siqi
  full_name: Huo, Siqi
  last_name: Huo
- first_name: Miguel A.
  full_name: Bañares, Miguel A.
  last_name: Bañares
- first_name: Marisol
  full_name: Martin-Gonzalez, Marisol
  last_name: Martin-Gonzalez
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
- first_name: Andreu
  full_name: Cabot, Andreu
  last_name: Cabot
- first_name: Min
  full_name: Hong, Min
  last_name: Hong
- first_name: Yu
  full_name: Liu, Yu
  id: 2A70014E-F248-11E8-B48F-1D18A9856A87
  last_name: Liu
  orcid: 0000-0001-7313-6740
- first_name: Khak Ho
  full_name: Lim, Khak Ho
  last_name: Lim
citation:
  ama: Meng W, Xu L, Lu S, et al. Thiol-Amine complexes for the synthesis and surface
    engineering of SnTe nanomaterials toward high thermoelectric performance. <i>ACS
    Nano</i>. 2025;19(38):34395-34407. doi:<a href="https://doi.org/10.1021/acsnano.5c12627">10.1021/acsnano.5c12627</a>
  apa: Meng, W., Xu, L., Lu, S., Li, M., Li, M., Zhang, Y., … Lim, K. H. (2025). Thiol-Amine
    complexes for the synthesis and surface engineering of SnTe nanomaterials toward
    high thermoelectric performance. <i>ACS Nano</i>. American Chemical Society. <a
    href="https://doi.org/10.1021/acsnano.5c12627">https://doi.org/10.1021/acsnano.5c12627</a>
  chicago: Meng, Weite, Lixiang Xu, Shaoqing Lu, Mingquan Li, Mengyao Li, Yu Zhang,
    Qingyue Wang, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering
    of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>.
    American Chemical Society, 2025. <a href="https://doi.org/10.1021/acsnano.5c12627">https://doi.org/10.1021/acsnano.5c12627</a>.
  ieee: W. Meng <i>et al.</i>, “Thiol-Amine complexes for the synthesis and surface
    engineering of SnTe nanomaterials toward high thermoelectric performance,” <i>ACS
    Nano</i>, vol. 19, no. 38. American Chemical Society, pp. 34395–34407, 2025.
  ista: Meng W, Xu L, Lu S, Li M, Li M, Zhang Y, Wang Q, Wang WJ, Huo S, Bañares MA,
    Martin-Gonzalez M, Ibáñez M, Cabot A, Hong M, Liu Y, Lim KH. 2025. Thiol-Amine
    complexes for the synthesis and surface engineering of SnTe nanomaterials toward
    high thermoelectric performance. ACS Nano. 19(38), 34395–34407.
  mla: Meng, Weite, et al. “Thiol-Amine Complexes for the Synthesis and Surface Engineering
    of SnTe Nanomaterials toward High Thermoelectric Performance.” <i>ACS Nano</i>,
    vol. 19, no. 38, American Chemical Society, 2025, pp. 34395–407, doi:<a href="https://doi.org/10.1021/acsnano.5c12627">10.1021/acsnano.5c12627</a>.
  short: W. Meng, L. Xu, S. Lu, M. Li, M. Li, Y. Zhang, Q. Wang, W.J. Wang, S. Huo,
    M.A. Bañares, M. Martin-Gonzalez, M. Ibáñez, A. Cabot, M. Hong, Y. Liu, K.H. Lim,
    ACS Nano 19 (2025) 34395–34407.
date_created: 2025-10-05T22:01:35Z
date_published: 2025-09-30T00:00:00Z
date_updated: 2025-12-01T12:50:24Z
day: '30'
department:
- _id: MaIb
doi: 10.1021/acsnano.5c12627
external_id:
  isi:
  - '001575398100001'
  pmid:
  - '40974325'
intvolume: '        19'
isi: 1
issue: '38'
language:
- iso: eng
month: '09'
oa_version: None
page: 34395-34407
pmid: 1
publication: ACS Nano
publication_identifier:
  eissn:
  - 1936-086X
  issn:
  - 1936-0851
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Thiol-Amine complexes for the synthesis and surface engineering of SnTe nanomaterials
  toward high thermoelectric performance
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 19
year: '2025'
...
---
OA_type: closed access
_id: '20427'
abstract:
- lang: eng
  text: Animal cells migrating up chemotactic gradients often show speed oscillations.
    A new study describes a molecular circuit that switches zebrafish germ cells between
    phases of straight runs, tumbling and directional reorientation.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Ziqiang
  full_name: Li, Ziqiang
  id: 922e68bb-1727-11ee-857c-966e8cc1b6c3
  last_name: Li
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: 'LI Z, Sixt MK. Cell migration: How animal cells run and tumble. <i>Current
    Biology</i>. 2025;35(18):R890-R892. doi:<a href="https://doi.org/10.1016/j.cub.2025.08.016">10.1016/j.cub.2025.08.016</a>'
  apa: 'LI, Z., &#38; Sixt, M. K. (2025). Cell migration: How animal cells run and
    tumble. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2025.08.016">https://doi.org/10.1016/j.cub.2025.08.016</a>'
  chicago: 'LI, ZIQIANG, and Michael K Sixt. “Cell Migration: How Animal Cells Run
    and Tumble.” <i>Current Biology</i>. Elsevier, 2025. <a href="https://doi.org/10.1016/j.cub.2025.08.016">https://doi.org/10.1016/j.cub.2025.08.016</a>.'
  ieee: 'Z. LI and M. K. Sixt, “Cell migration: How animal cells run and tumble,”
    <i>Current Biology</i>, vol. 35, no. 18. Elsevier, pp. R890–R892, 2025.'
  ista: 'LI Z, Sixt MK. 2025. Cell migration: How animal cells run and tumble. Current
    Biology. 35(18), R890–R892.'
  mla: 'LI, ZIQIANG, and Michael K. Sixt. “Cell Migration: How Animal Cells Run and
    Tumble.” <i>Current Biology</i>, vol. 35, no. 18, Elsevier, 2025, pp. R890–92,
    doi:<a href="https://doi.org/10.1016/j.cub.2025.08.016">10.1016/j.cub.2025.08.016</a>.'
  short: Z. LI, M.K. Sixt, Current Biology 35 (2025) R890–R892.
corr_author: '1'
date_created: 2025-10-05T22:01:35Z
date_published: 2025-09-22T00:00:00Z
date_updated: 2025-12-01T12:54:02Z
day: '22'
department:
- _id: MiSi
doi: 10.1016/j.cub.2025.08.016
external_id:
  isi:
  - '001592664700001'
  pmid:
  - '40987270'
intvolume: '        35'
isi: 1
issue: '18'
language:
- iso: eng
month: '09'
oa_version: None
page: R890-R892
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Cell migration: How animal cells run and tumble'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '20428'
acknowledgement: The Graphical Abstract was created with the AI tool https://wordart.com.
  This content is not subject to CC BY 4.0.
article_processing_charge: No
article_type: editorial
author:
- first_name: Timothy
  full_name: Noël, Timothy
  last_name: Noël
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
citation:
  ama: Noël T, Pieber B. Photocatalysis and photochemistry in organic synthesis. <i>Beilstein
    Journal of Organic Chemistry</i>. 2025;21:1645-1647. doi:<a href="https://doi.org/10.3762/bjoc.21.128">10.3762/bjoc.21.128</a>
  apa: Noël, T., &#38; Pieber, B. (2025). Photocatalysis and photochemistry in organic
    synthesis. <i>Beilstein Journal of Organic Chemistry</i>. Beilstein Institut.
    <a href="https://doi.org/10.3762/bjoc.21.128">https://doi.org/10.3762/bjoc.21.128</a>
  chicago: Noël, Timothy, and Bartholomäus Pieber. “Photocatalysis and Photochemistry
    in Organic Synthesis.” <i>Beilstein Journal of Organic Chemistry</i>. Beilstein
    Institut, 2025. <a href="https://doi.org/10.3762/bjoc.21.128">https://doi.org/10.3762/bjoc.21.128</a>.
  ieee: T. Noël and B. Pieber, “Photocatalysis and photochemistry in organic synthesis,”
    <i>Beilstein Journal of Organic Chemistry</i>, vol. 21. Beilstein Institut, pp.
    1645–1647, 2025.
  ista: Noël T, Pieber B. 2025. Photocatalysis and photochemistry in organic synthesis.
    Beilstein Journal of Organic Chemistry. 21, 1645–1647.
  mla: Noël, Timothy, and Bartholomäus Pieber. “Photocatalysis and Photochemistry
    in Organic Synthesis.” <i>Beilstein Journal of Organic Chemistry</i>, vol. 21,
    Beilstein Institut, 2025, pp. 1645–47, doi:<a href="https://doi.org/10.3762/bjoc.21.128">10.3762/bjoc.21.128</a>.
  short: T. Noël, B. Pieber, Beilstein Journal of Organic Chemistry 21 (2025) 1645–1647.
corr_author: '1'
date_created: 2025-10-05T22:01:35Z
date_published: 2025-08-18T00:00:00Z
date_updated: 2025-10-13T11:21:01Z
day: '18'
ddc:
- '540'
department:
- _id: BaPi
doi: 10.3762/bjoc.21.128
external_id:
  pmid:
  - '40927207'
file:
- access_level: open_access
  checksum: 45a4ac237e55fdcad168aeb5bd5be61d
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T11:18:02Z
  date_updated: 2025-10-13T11:18:02Z
  file_id: '20462'
  file_name: 2025_BeilsteinJourOrgChemistry_Noel.pdf
  file_size: 117869
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T11:18:02Z
has_accepted_license: '1'
intvolume: '        21'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 1645-1647
pmid: 1
publication: Beilstein Journal of Organic Chemistry
publication_identifier:
  eissn:
  - 1860-5397
publication_status: published
publisher: Beilstein Institut
quality_controlled: '1'
scopus_import: '1'
status: public
title: Photocatalysis and photochemistry in organic synthesis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2025'
...
---
OA_type: closed access
_id: '20429'
abstract:
- lang: eng
  text: Plant–plant interactions are key to understanding ecosystem services and shaping
    restoration strategies, as they can produce either negative or positive effects,
    determining species establishment and growth. Recognizing these interactions during
    early-life stages provides valuable insights for restoration in human-disturbed
    areas. One promising approach is nucleation planting, which establishes small
    clusters of native species in strategically selected sites, being particularly
    useful in sites with large herbivores. In southern Patagonia, livestock production
    has historically been the main economic activity, severely impacting extensive
    areas of Nothofagus antarctica forest through grazing and intentional burning
    to increase forage. In this context, nucleation planting with Berberis microphylla,
    a non-palatable shrub, could foster forest recovery in degraded sites. To evaluate
    this, we conducted an experiment testing the response of trees to varying shrub
    number, while also assessing intraspecific effects in both species. We measured
    survival, biomass, and functional traits. Results showed that the combination
    of four shrubs surrounding a single tree maintained tree survival at levels comparable
    to trees growing alone, while seedlings exhibited conspecific negative plant number
    dependence. Additionally, B. microphylla increased its below- to above-ground
    biomass ratio under higher plant number, indicating resource reallocation and
    niche differentiation through spatial separation of root systems.
article_processing_charge: No
article_type: original
author:
- first_name: Gimena Noemí
  full_name: Bustamante, Gimena Noemí
  last_name: Bustamante
- first_name: Miriam Elisabet
  full_name: Arena, Miriam Elisabet
  last_name: Arena
- first_name: Luciano
  full_name: Selzer, Luciano
  last_name: Selzer
- first_name: Matthew
  full_name: Ruggirello, Matthew
  last_name: Ruggirello
- first_name: Paula
  full_name: Rodríguez, Paula
  last_name: Rodríguez
- first_name: Samuele
  full_name: Pedrazzani, Samuele
  last_name: Pedrazzani
- first_name: Jose Antonio
  full_name: Navarro-Cano, Jose Antonio
  last_name: Navarro-Cano
- first_name: Rosina Matilde
  full_name: Soler Schaller, Rosina Matilde
  id: 9e668447-8c32-11ed-b0c7-8dc2d7b80803
  last_name: Soler Schaller
citation:
  ama: 'Bustamante GN, Arena ME, Selzer L, et al. Biotic interactions between trees
    and colonizing shrubs: Implications for active restoration in southern Patagonian
    forests. <i>Plant Ecology</i>. 2025;226:1301-1313. doi:<a href="https://doi.org/10.1007/s11258-025-01568-0">10.1007/s11258-025-01568-0</a>'
  apa: 'Bustamante, G. N., Arena, M. E., Selzer, L., Ruggirello, M., Rodríguez, P.,
    Pedrazzani, S., … Soler Schaller, R. M. (2025). Biotic interactions between trees
    and colonizing shrubs: Implications for active restoration in southern Patagonian
    forests. <i>Plant Ecology</i>. Springer Nature. <a href="https://doi.org/10.1007/s11258-025-01568-0">https://doi.org/10.1007/s11258-025-01568-0</a>'
  chicago: 'Bustamante, Gimena Noemí, Miriam Elisabet Arena, Luciano Selzer, Matthew
    Ruggirello, Paula Rodríguez, Samuele Pedrazzani, Jose Antonio Navarro-Cano, and
    Rosina Matilde Soler Schaller. “Biotic Interactions between Trees and Colonizing
    Shrubs: Implications for Active Restoration in Southern Patagonian Forests.” <i>Plant
    Ecology</i>. Springer Nature, 2025. <a href="https://doi.org/10.1007/s11258-025-01568-0">https://doi.org/10.1007/s11258-025-01568-0</a>.'
  ieee: 'G. N. Bustamante <i>et al.</i>, “Biotic interactions between trees and colonizing
    shrubs: Implications for active restoration in southern Patagonian forests,” <i>Plant
    Ecology</i>, vol. 226. Springer Nature, pp. 1301–1313, 2025.'
  ista: 'Bustamante GN, Arena ME, Selzer L, Ruggirello M, Rodríguez P, Pedrazzani
    S, Navarro-Cano JA, Soler Schaller RM. 2025. Biotic interactions between trees
    and colonizing shrubs: Implications for active restoration in southern Patagonian
    forests. Plant Ecology. 226, 1301–1313.'
  mla: 'Bustamante, Gimena Noemí, et al. “Biotic Interactions between Trees and Colonizing
    Shrubs: Implications for Active Restoration in Southern Patagonian Forests.” <i>Plant
    Ecology</i>, vol. 226, Springer Nature, 2025, pp. 1301–13, doi:<a href="https://doi.org/10.1007/s11258-025-01568-0">10.1007/s11258-025-01568-0</a>.'
  short: G.N. Bustamante, M.E. Arena, L. Selzer, M. Ruggirello, P. Rodríguez, S. Pedrazzani,
    J.A. Navarro-Cano, R.M. Soler Schaller, Plant Ecology 226 (2025) 1301–1313.
date_created: 2025-10-05T22:01:36Z
date_published: 2025-12-01T00:00:00Z
date_updated: 2026-01-05T13:23:57Z
day: '01'
department:
- _id: NiBa
doi: 10.1007/s11258-025-01568-0
external_id:
  isi:
  - '001581599800001'
intvolume: '       226'
isi: 1
language:
- iso: eng
month: '12'
oa_version: None
page: 1301-1313
publication: Plant Ecology
publication_identifier:
  eissn:
  - 1573-5052
  issn:
  - 1385-0237
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Biotic interactions between trees and colonizing shrubs: Implications for
  active restoration in southern Patagonian forests'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 226
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20430'
abstract:
- lang: eng
  text: Protein design has focused on the design of ground states, ensuring that they
    are sufficiently low energy to be highly populated1. Designing the kinetics and
    dynamics of a system requires, in addition, the design of excited states that
    are traversed in transitions from one low-lying state to another2,3. This is a
    challenging task because such states must be sufficiently strained to be poorly
    populated, but not so strained that they are not populated at all, and because
    protein design methods have focused on generating near-ideal structures4,5,6,7.
    Here we describe a general approach for designing systems that use an induced-fit
    power stroke8 to generate a structurally frustrated9 and strained excited state,
    allosterically driving protein complex dissociation. X-ray crystallography, double
    electron–electron resonance spectroscopy and kinetic binding measurements show
    that incorporating excited states enables the design of effector-induced increases
    in dissociation rates as high as 5,700-fold. We highlight the power of this approach
    by designing rapid biosensors, kinetically controlled circuits and cytokine mimics
    that can be dissociated from their receptors within seconds, enabling dissection
    of the temporal dynamics of interleukin-2 signalling.
acknowledgement: We thank P. J. Y. Leung, K. L. Shelley, A. Pillai, C. Demakis, M.
  Exposit, K. Thompson, C. Savvides, R. J. Ragotte, G. Ahn and M. Glögl for discussions
  and technical support; K. VanWormer and L. Goldschmidt for technical support; S.
  R. Gerben and A. Murray for protein production support; and X. Li, M. Lamb, Z. Taylor
  and V. Adebomi for LC–MS support. This work was supported by the Audacious Project
  at the Institute for Protein Design (A.J.B., A.K., J.D.L.C., E.B. and A.K.B.); by
  a gift from Microsoft (A.J.B.); by the Nordstrom Barrier Institute for Protein Design
  Directors Fund (M.H.A. and F.P.); by Bill and Melinda Gates Foundation OPP1156262
  (A.K. and J.D.L.C.); by the Open Philanthropy Project Improving Protein Design Fund
  (E.B. and A.K.B.); by the National Institutes of Health (NIH) National Institute
  of Allergy and Infectious Disease grant R0AI160052 (A.K.B.); by CRI Irvington Postdoctoral
  Fellowship 315511 (Y.Z.); by National Cancer Institute K00 award 4K00CA274708 (M.O.);
  by National Science Foundation grant MCB 2119837 and NIH grant GM115805 (W.H.R.
  and D.M.Z.); by NIH grant GM151956 (S.S.); by NIH AI-51321 (K.C.G.); by the DFG
  grants PI 405/15 and SFB 1557 (C.P. and J.P.); and by the Howard Hughes Medical
  Institute (A.K.B., K.C.G. and D.B.). The EPR spectrometer used for the DEER experiments
  was in part supported by NIH grant S10OD021557. This research used resources (FMX/AMX)
  of the National Synchrotron Light Source II, a US Department of Energy (DoE) Office
  of Science User Facility operated for the DOE Office of Science by Brookhaven National
  Laboratory under contract DE-SC0012704. The Center for BioMolecular Structure (CBMS)
  is supported mainly by the NIH National Institute of General Medical Sciences (NIGMS)
  through a Center Core P30 Grant (P30GM133893), and by the DoE Office of Biological
  and Environmental Research (KP1607011). This work is based on research performed
  at the Northeastern Collaborative Access Team beamlines, which are funded by the
  NIGMS (P30 GM124165). The research used resources of the Advanced Photon Source,
  a US DoE Office of Science User Facility operated for the DoE Office of Science
  by Argonne National Laboratory under contract DE-AC02-06CH11357. The Berkeley Center
  for Structural Biology is supported by the NIH, NIGMS and the Howard Hughes Medical
  Institute. The Advanced Light Source is supported by the Director, Office of Science,
  Office of Basic Energy Sciences and US DoE (DE-AC02-05CH11231).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Adam J.
  full_name: Broerman, Adam J.
  last_name: Broerman
- first_name: Christoph
  full_name: Pollmann, Christoph
  last_name: Pollmann
- first_name: Yang
  full_name: Zhao, Yang
  last_name: Zhao
- first_name: Mauriz A.
  full_name: Lichtenstein, Mauriz A.
  last_name: Lichtenstein
- first_name: Mark D.
  full_name: Jackson, Mark D.
  last_name: Jackson
- first_name: Maxx H.
  full_name: Tessmer, Maxx H.
  last_name: Tessmer
- first_name: Won Hee
  full_name: Ryu, Won Hee
  last_name: Ryu
- first_name: Masato
  full_name: Ogishi, Masato
  last_name: Ogishi
- first_name: Mohamad H.
  full_name: Abedi, Mohamad H.
  last_name: Abedi
- first_name: Danny D.
  full_name: Sahtoe, Danny D.
  last_name: Sahtoe
- first_name: Aza
  full_name: Allen, Aza
  last_name: Allen
- first_name: Alex
  full_name: Kang, Alex
  last_name: Kang
- first_name: Joshmyn
  full_name: De La Cruz, Joshmyn
  last_name: De La Cruz
- first_name: Evans
  full_name: Brackenbrough, Evans
  last_name: Brackenbrough
- first_name: Banumathi
  full_name: Sankaran, Banumathi
  last_name: Sankaran
- first_name: Asim K.
  full_name: Bera, Asim K.
  last_name: Bera
- first_name: Daniel M.
  full_name: Zuckerman, Daniel M.
  last_name: Zuckerman
- first_name: Stefan
  full_name: Stoll, Stefan
  last_name: Stoll
- first_name: K. Christopher
  full_name: Garcia, K. Christopher
  last_name: Garcia
- first_name: Florian M
  full_name: Praetorius, Florian M
  id: dfec9381-4341-11ee-8fd8-faa02bba7d62
  last_name: Praetorius
  orcid: 0000-0002-0806-8101
- first_name: Jacob
  full_name: Piehler, Jacob
  last_name: Piehler
- first_name: David
  full_name: Baker, David
  last_name: Baker
citation:
  ama: Broerman AJ, Pollmann C, Zhao Y, et al. Design of facilitated dissociation
    enables timing of cytokine signalling. <i>Nature</i>. 2025;647:528-535. doi:<a
    href="https://doi.org/10.1038/s41586-025-09549-z">10.1038/s41586-025-09549-z</a>
  apa: Broerman, A. J., Pollmann, C., Zhao, Y., Lichtenstein, M. A., Jackson, M. D.,
    Tessmer, M. H., … Baker, D. (2025). Design of facilitated dissociation enables
    timing of cytokine signalling. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/s41586-025-09549-z">https://doi.org/10.1038/s41586-025-09549-z</a>
  chicago: Broerman, Adam J., Christoph Pollmann, Yang Zhao, Mauriz A. Lichtenstein,
    Mark D. Jackson, Maxx H. Tessmer, Won Hee Ryu, et al. “Design of Facilitated Dissociation
    Enables Timing of Cytokine Signalling.” <i>Nature</i>. Springer Nature, 2025.
    <a href="https://doi.org/10.1038/s41586-025-09549-z">https://doi.org/10.1038/s41586-025-09549-z</a>.
  ieee: A. J. Broerman <i>et al.</i>, “Design of facilitated dissociation enables
    timing of cytokine signalling,” <i>Nature</i>, vol. 647. Springer Nature, pp.
    528–535, 2025.
  ista: Broerman AJ, Pollmann C, Zhao Y, Lichtenstein MA, Jackson MD, Tessmer MH,
    Ryu WH, Ogishi M, Abedi MH, Sahtoe DD, Allen A, Kang A, De La Cruz J, Brackenbrough
    E, Sankaran B, Bera AK, Zuckerman DM, Stoll S, Garcia KC, Praetorius FM, Piehler
    J, Baker D. 2025. Design of facilitated dissociation enables timing of cytokine
    signalling. Nature. 647, 528–535.
  mla: Broerman, Adam J., et al. “Design of Facilitated Dissociation Enables Timing
    of Cytokine Signalling.” <i>Nature</i>, vol. 647, Springer Nature, 2025, pp. 528–35,
    doi:<a href="https://doi.org/10.1038/s41586-025-09549-z">10.1038/s41586-025-09549-z</a>.
  short: A.J. Broerman, C. Pollmann, Y. Zhao, M.A. Lichtenstein, M.D. Jackson, M.H.
    Tessmer, W.H. Ryu, M. Ogishi, M.H. Abedi, D.D. Sahtoe, A. Allen, A. Kang, J. De
    La Cruz, E. Brackenbrough, B. Sankaran, A.K. Bera, D.M. Zuckerman, S. Stoll, K.C.
    Garcia, F.M. Praetorius, J. Piehler, D. Baker, Nature 647 (2025) 528–535.
corr_author: '1'
date_created: 2025-10-05T22:01:36Z
date_published: 2025-11-13T00:00:00Z
date_updated: 2026-01-05T13:18:17Z
day: '13'
ddc:
- '570'
department:
- _id: FlPr
doi: 10.1038/s41586-025-09549-z
external_id:
  isi:
  - '001577755600001'
  pmid:
  - '40993395'
file:
- access_level: open_access
  checksum: b4ec44134e2eb320a724dc29158dfda2
  content_type: application/pdf
  creator: dernst
  date_created: 2026-01-05T13:17:47Z
  date_updated: 2026-01-05T13:17:47Z
  file_id: '20951'
  file_name: 2025_Nature_Broerman.pdf
  file_size: 22099921
  relation: main_file
  success: 1
file_date_updated: 2026-01-05T13:17:47Z
has_accepted_license: '1'
intvolume: '       647'
isi: 1
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 528-535
pmid: 1
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Design of facilitated dissociation enables timing of cytokine signalling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 647
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20431'
abstract:
- lang: eng
  text: Haptotaxis is the process of directed cell migration along gradients of extracellular
    matrix density and is central to morphogenesis, immune responses and cancer invasion.
    It is commonly assumed that cells respond to these gradients by migrating directionally
    towards the regions of highest ligand density. In contrast with this view, here
    we show that cells exposed to micropatterned fibronectin gradients exhibit a wide
    range of complex trajectories, including directed haptotactic migration up the
    gradient but also linear oscillations and circles with extended periods of migration
    down the gradient. To explain this behaviour, we developed a biophysical model
    of haptotactic cell migration based on a coarse-grained molecular clutch model
    coupled to persistent stochastic polarity dynamics. Although initial haptotactic
    migration is explained by the differential friction at the front and back of the
    cell, the observed complex trajectories over longer timescales arise from the
    interplay between differential friction, persistence and physical confinement.
    Overall, our study reveals that confinement and persistence modulate the ability
    of cells to sense and respond to haptotactic cues and provides a framework for
    understanding how cells navigate complex environments.
acknowledgement: We thank all the members of our groups for discussions and support.
  We thank A. Menéndez, S. Usieto, M. Purciolas and E. Coderch for technical assistance.
  We thank G. Charras (London Centre for Nanotechnology, UK) and M. Sheetz (Columbia
  University, USA) for sharing cells used in this work. We thank J. Ivaska (University
  of Turku, Finland) for sharing integrin α5-GFP DNA plasmid. We thank P. Guillamat
  for technical advice and A. Labernardie for providing the microfluidic channels.
  We thank M. Gómez-González for sharing the 2D traction microscopy algorithm. Finally,
  we thank P. Guillamat, J. Abenza, G. Ceada, L. Faure, E. Dalaka, M. Matejčić, A.
  Beedle, I. Granero, O. Baguer, A. Albajar and N. Chahare for discussions. This paper
  was funded by the Generalitat de Catalunya (Grant Nos. AGAUR SGR-2017-01602 to X.T.
  and 2021 SGR 00523 to R.S. and the CERCA Programme and ICREA Academia awards to
  P.R.-C.), the Spanish Ministry for Science and Innovation MICCINN/FEDER (Grant Nos.
  PID2021-128635NB-I00, MCIN/AEI/10.13039/501100011033 and ERDF-EU A way of making
  Europe to X.T., PID2021-128674OB-I00 and CNS2022-135533 to R.S. and PID2019-110298GB-I00
  to P.R.-C.), the European Research Council (Grant Nos. 101097753 to P.R.-C. and
  Adv-883739 to X.T.), Fundació la Marató de TV3 (Project Award 201903-30-31-32 to
  X.T.), the European Commission (Grant No. H2020-FETPROACT-01-2016-731957 to P.R.-C.
  and X.T.) and La Caixa Foundation (Grant No. LCF/PR/HR20/52400004 to P.R.-C. and
  X.T.). R.S. is a Serra-Hunter fellow. D.B.B. was supported by the NOMIS foundation
  as a NOMIS fellow, by the European Molecular Biology Organization (Postdoctoral
  Fellowship ALTF 343-2022) and by the Austrian Academy of Sciences through an APART-MINT
  Fellowship. I.C.F. acknowledges support from the European Foundation for the Study
  of Chronic Liver Failure. IBEC is recipient of a Severo Ochoa Award of Excellence
  from MINECO.
article_processing_charge: No
article_type: original
author:
- first_name: Isabela Corina
  full_name: Fortunato, Isabela Corina
  last_name: Fortunato
- first_name: David
  full_name: Brückner, David
  id: e1e86031-6537-11eb-953a-f7ab92be508d
  last_name: Brückner
  orcid: 0000-0001-7205-2975
- first_name: Steffen
  full_name: Grosser, Steffen
  last_name: Grosser
- first_name: Rohit
  full_name: Nautiyal, Rohit
  last_name: Nautiyal
- first_name: Leone
  full_name: Rossetti, Leone
  last_name: Rossetti
- first_name: Miquel
  full_name: Bosch-Padrós, Miquel
  last_name: Bosch-Padrós
- first_name: Jonel
  full_name: Trebicka, Jonel
  last_name: Trebicka
- first_name: Pere
  full_name: Roca-Cusachs, Pere
  last_name: Roca-Cusachs
- first_name: Raimon
  full_name: Sunyer, Raimon
  last_name: Sunyer
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
- first_name: Xavier
  full_name: Trepat, Xavier
  last_name: Trepat
citation:
  ama: Fortunato IC, Brückner D, Grosser S, et al. Single-cell migration along and
    against confined haptotactic gradients. <i>Nature Physics</i>. 2025;21:1638-1647.
    doi:<a href="https://doi.org/10.1038/s41567-025-03015-3">10.1038/s41567-025-03015-3</a>
  apa: Fortunato, I. C., Brückner, D., Grosser, S., Nautiyal, R., Rossetti, L., Bosch-Padrós,
    M., … Trepat, X. (2025). Single-cell migration along and against confined haptotactic
    gradients. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-025-03015-3">https://doi.org/10.1038/s41567-025-03015-3</a>
  chicago: Fortunato, Isabela Corina, David Brückner, Steffen Grosser, Rohit Nautiyal,
    Leone Rossetti, Miquel Bosch-Padrós, Jonel Trebicka, et al. “Single-Cell Migration
    along and against Confined Haptotactic Gradients.” <i>Nature Physics</i>. Springer
    Nature, 2025. <a href="https://doi.org/10.1038/s41567-025-03015-3">https://doi.org/10.1038/s41567-025-03015-3</a>.
  ieee: I. C. Fortunato <i>et al.</i>, “Single-cell migration along and against confined
    haptotactic gradients,” <i>Nature Physics</i>, vol. 21. Springer Nature, pp. 1638–1647,
    2025.
  ista: Fortunato IC, Brückner D, Grosser S, Nautiyal R, Rossetti L, Bosch-Padrós
    M, Trebicka J, Roca-Cusachs P, Sunyer R, Hannezo EB, Trepat X. 2025. Single-cell
    migration along and against confined haptotactic gradients. Nature Physics. 21,
    1638–1647.
  mla: Fortunato, Isabela Corina, et al. “Single-Cell Migration along and against
    Confined Haptotactic Gradients.” <i>Nature Physics</i>, vol. 21, Springer Nature,
    2025, pp. 1638–47, doi:<a href="https://doi.org/10.1038/s41567-025-03015-3">10.1038/s41567-025-03015-3</a>.
  short: I.C. Fortunato, D. Brückner, S. Grosser, R. Nautiyal, L. Rossetti, M. Bosch-Padrós,
    J. Trebicka, P. Roca-Cusachs, R. Sunyer, E.B. Hannezo, X. Trepat, Nature Physics
    21 (2025) 1638–1647.
corr_author: '1'
date_created: 2025-10-05T22:01:36Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2026-01-05T14:26:28Z
day: '01'
department:
- _id: EdHa
doi: 10.1038/s41567-025-03015-3
external_id:
  isi:
  - '001581659900001'
intvolume: '        21'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2024.12.02.626413
month: '10'
oa: 1
oa_version: Preprint
page: 1638-1647
project:
- _id: 34e2a5b5-11ca-11ed-8bc3-b2265616ef0b
  grant_number: ALTF 343-2022
  name: A mechano-chemical theory for stem cell fate decisions in organoid development
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Single-cell migration along and against confined haptotactic gradients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2025'
...
---
OA_type: closed access
_id: '20432'
abstract:
- lang: eng
  text: A rapidly increasing body of work reporting phenomena associated with lattice
    vibrations carrying angular momentum has led to the emergence of the field of
    chiral phonons. Some of these properties, such as the phonon magnetic moment,
    also occur in achiral phonons that are circularly or elliptically polarized, while
    the presence of chirality has additional implications for the types of interaction
    allowed between the phonons and light, electrons and other quasiparticles. In
    this Perspective we introduce a framework for classifying phonons with angular
    momentum, and provide illustrations of the different types using examples from
    the recent literature. Specifically, we suggest the term ‘axial phonon’ to encompass
    all phonons that carry angular momentum, real or pseudo, and reserve the term
    ‘chiral phonon’ for those phonons that break improper rotational symmetry. We
    hope that this scheme provides clarification on the matter of phonon chirality
    and will serve as a guide for future research.
acknowledgement: We thank A. V. Balatsky, E. Bousquet, A. Disa, S. Kamba, L. Klebl,
  R. Merlin, A. Srivastava, A. Stroppa, M. Udina, P. Wong and D. Xiao for valuable
  discussions. M.B. acknowledges support from SNSF Ambizione project number PZ00P2_216089.
  P.B. and U.N. acknowledge funding from the Deutsche Forschungsgemeinschaft (grant
  number 541503763). B.F. acknowledges support from the National Science Foundation
  under grant number NSF DMR-2144086. G.G. acknowledges support from STeP2 number
  ANR-22-EXES-0013, QuantExt number ANR-23-CE30-0001-01, Audace CEA number ANR-24-RRII-0004
  and the École Polytechnique foundation. A.I.K. acknowledges the Nederlandse Organisatie
  voor Wetenschappelijk Onderzoek (NWO-I) for their financial contribution, including
  the support of the HFML-FELIX Laboratory. D.M.J. acknowledges support from Tel Aviv
  University and ERC Starting Grant CHIRALPHONONICS grant number 101166037. S.F.M.
  acknowledges funding from the Deutsche Forschungsgemeinschaft (grant number 469405347).
  C.P.R. and N.A.S. were supported by ETH Zurich and by the European Union and Horizon
  2020, grant agreement numbers 810451 and 101030352. R.M.G. acknowledges support
  from the Swedish Research Council (VR starting grant number 2022-03350), the Olle
  Engkvist Foundation (grant number 229-0443), the Royal Physiographic Society in
  Lund (Horisont), the Knut and Alice Wallenberg Foundation (grant number 2023.0087)
  and Chalmers University of Technology via the Department of Physics and the Areas
  of Advance Nano and Materials Science. Q.N. is supported by the National Natural
  Science Foundation of China (grant number 12234017) and the National Key Research
  and Development Program of China (grant number 2023YFA1406300). H.R. acknowledges
  funding from the Engineering and Physical Sciences Research Council (grant number
  UKRI122) and Royal Society (grant number IES\R2\242309). T.S. acknowledges support
  from MEXT X-NICS (grant number JPJ011438), NINS OML Project (grant number OML012301)
  and JST CREST (grant number JPMJCR24R5). H.Z. acknowledges support from the Welch
  Foundation (grant number C-2128) and the National Science Foundation (grant number
  DMR-2240106). We acknowledge support from the Centre Européen de Calcul Atomique
  et Moléculaire (CECAM) in connection to organizing the workshop "Chiral Phonons
  in Quantum Materials", held in 2023, where the idea for this paper emerged.
article_processing_charge: No
article_type: original
author:
- first_name: Dominik M.
  full_name: Juraschek, Dominik M.
  last_name: Juraschek
- first_name: R. Matthias
  full_name: Geilhufe, R. Matthias
  last_name: Geilhufe
- first_name: Hanyu
  full_name: Zhu, Hanyu
  last_name: Zhu
- first_name: Martina
  full_name: Basini, Martina
  last_name: Basini
- first_name: Peter
  full_name: Baum, Peter
  last_name: Baum
- first_name: Andrey
  full_name: Baydin, Andrey
  last_name: Baydin
- first_name: Swati
  full_name: Chaudhary, Swati
  last_name: Chaudhary
- first_name: Michael
  full_name: Fechner, Michael
  last_name: Fechner
- first_name: Benedetta
  full_name: Flebus, Benedetta
  last_name: Flebus
- first_name: Gael
  full_name: Grissonnanche, Gael
  last_name: Grissonnanche
- first_name: Andrei I.
  full_name: Kirilyuk, Andrei I.
  last_name: Kirilyuk
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Sebastian F.
  full_name: Maehrlein, Sebastian F.
  last_name: Maehrlein
- first_name: Maxime
  full_name: Mignolet, Maxime
  last_name: Mignolet
- first_name: Shuichi
  full_name: Murakami, Shuichi
  last_name: Murakami
- first_name: Qian
  full_name: Niu, Qian
  last_name: Niu
- first_name: Ulrich
  full_name: Nowak, Ulrich
  last_name: Nowak
- first_name: Carl P.
  full_name: Romao, Carl P.
  last_name: Romao
- first_name: Habib
  full_name: Rostami, Habib
  last_name: Rostami
- first_name: Takuya
  full_name: Satoh, Takuya
  last_name: Satoh
- first_name: Nicola A.
  full_name: Spaldin, Nicola A.
  last_name: Spaldin
- first_name: Hiroki
  full_name: Ueda, Hiroki
  last_name: Ueda
- first_name: Lifa
  full_name: Zhang, Lifa
  last_name: Zhang
citation:
  ama: Juraschek DM, Geilhufe RM, Zhu H, et al. Chiral phonons. <i>Nature Physics</i>.
    2025;21:1532-1540. doi:<a href="https://doi.org/10.1038/s41567-025-03001-9">10.1038/s41567-025-03001-9</a>
  apa: Juraschek, D. M., Geilhufe, R. M., Zhu, H., Basini, M., Baum, P., Baydin, A.,
    … Zhang, L. (2025). Chiral phonons. <i>Nature Physics</i>. Springer Nature. <a
    href="https://doi.org/10.1038/s41567-025-03001-9">https://doi.org/10.1038/s41567-025-03001-9</a>
  chicago: Juraschek, Dominik M., R. Matthias Geilhufe, Hanyu Zhu, Martina Basini,
    Peter Baum, Andrey Baydin, Swati Chaudhary, et al. “Chiral Phonons.” <i>Nature
    Physics</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s41567-025-03001-9">https://doi.org/10.1038/s41567-025-03001-9</a>.
  ieee: D. M. Juraschek <i>et al.</i>, “Chiral phonons,” <i>Nature Physics</i>, vol.
    21. Springer Nature, pp. 1532–1540, 2025.
  ista: Juraschek DM, Geilhufe RM, Zhu H, Basini M, Baum P, Baydin A, Chaudhary S,
    Fechner M, Flebus B, Grissonnanche G, Kirilyuk AI, Lemeshko M, Maehrlein SF, Mignolet
    M, Murakami S, Niu Q, Nowak U, Romao CP, Rostami H, Satoh T, Spaldin NA, Ueda
    H, Zhang L. 2025. Chiral phonons. Nature Physics. 21, 1532–1540.
  mla: Juraschek, Dominik M., et al. “Chiral Phonons.” <i>Nature Physics</i>, vol.
    21, Springer Nature, 2025, pp. 1532–40, doi:<a href="https://doi.org/10.1038/s41567-025-03001-9">10.1038/s41567-025-03001-9</a>.
  short: D.M. Juraschek, R.M. Geilhufe, H. Zhu, M. Basini, P. Baum, A. Baydin, S.
    Chaudhary, M. Fechner, B. Flebus, G. Grissonnanche, A.I. Kirilyuk, M. Lemeshko,
    S.F. Maehrlein, M. Mignolet, S. Murakami, Q. Niu, U. Nowak, C.P. Romao, H. Rostami,
    T. Satoh, N.A. Spaldin, H. Ueda, L. Zhang, Nature Physics 21 (2025) 1532–1540.
date_created: 2025-10-05T22:01:37Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2026-01-05T13:25:59Z
day: '01'
department:
- _id: MiLe
doi: 10.1038/s41567-025-03001-9
external_id:
  isi:
  - '001575765100001'
intvolume: '        21'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 1532-1540
publication: Nature Physics
publication_identifier:
  eissn:
  - 1745-2481
  issn:
  - 1745-2473
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Chiral phonons
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2025'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '20452'
abstract:
- lang: eng
  text: Accurate modeling of long-range forces is critical in atomistic simulations,
    as they play a central role in determining the properties of material and chemical
    systems. However, standard machine learning interatomic potentials (MLIPs) often
    rely on short-range approximations, limiting their applicability to systems with
    significant electrostatics and dispersion forces. We recently introduced the Latent
    Ewald Summation (LES) method, which captures long-range electrostatics without
    explicitly learning atomic charges or charge equilibration. We benchmark LES on
    diverse and challenging systems, including charged molecules, ionic liquids, electrolyte
    solutions, polar dipeptides, surface adsorption, electrolyte/solid interfaces,
    and solid-solid interfaces. Here we show that LES can reproduce the exact atomic
    charges for classical systems with fixed charges and can infer dipole and quadrupole
    moments, as well as the dipole derivative with respect to atomic positions, for
    quantum mechanical systems. Moreover, LES can achieve better accuracy in energy
    and force predictions compared to methods that explicitly learn from charges.
acknowledgement: We thank Chunyi Zhang for providing the TiO2(101)/NaCl+NaOH+HCl(aq)
  dataset and for useful discussions. We thank Jia-Xin Zhu for providing the Pt(111)/KF(aq)
  dataset. We thank Tsz Wai Ko and Jonas Finkler for useful discussions and for the
  DFT-optimized Au2-MgO(001) structures. We thank Junmin Chen for discussions. D.K
  and B.C. acknowledge funding from Toyota Research Institute Synthesis Advanced Research
  Challenge. D.S.K. and P.Z. acknowledge funding from BIDMaP Postdoctoral Fellowship.
article_number: '8763'
article_processing_charge: Yes
article_type: original
author:
- first_name: Daniel S.
  full_name: King, Daniel S.
  last_name: King
- first_name: Dongjin
  full_name: Kim, Dongjin
  last_name: Kim
- first_name: Peichen
  full_name: Zhong, Peichen
  last_name: Zhong
- first_name: Bingqing
  full_name: Cheng, Bingqing
  id: cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9
  last_name: Cheng
  orcid: 0000-0002-3584-9632
citation:
  ama: King DS, Kim D, Zhong P, Cheng B. Machine learning of charges and long-range
    interactions from energies and forces. <i>Nature Communications</i>. 2025;16.
    doi:<a href="https://doi.org/10.1038/s41467-025-63852-x">10.1038/s41467-025-63852-x</a>
  apa: King, D. S., Kim, D., Zhong, P., &#38; Cheng, B. (2025). Machine learning of
    charges and long-range interactions from energies and forces. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-025-63852-x">https://doi.org/10.1038/s41467-025-63852-x</a>
  chicago: King, Daniel S., Dongjin Kim, Peichen Zhong, and Bingqing Cheng. “Machine
    Learning of Charges and Long-Range Interactions from Energies and Forces.” <i>Nature
    Communications</i>. Springer Nature, 2025. <a href="https://doi.org/10.1038/s41467-025-63852-x">https://doi.org/10.1038/s41467-025-63852-x</a>.
  ieee: D. S. King, D. Kim, P. Zhong, and B. Cheng, “Machine learning of charges and
    long-range interactions from energies and forces,” <i>Nature Communications</i>,
    vol. 16. Springer Nature, 2025.
  ista: King DS, Kim D, Zhong P, Cheng B. 2025. Machine learning of charges and long-range
    interactions from energies and forces. Nature Communications. 16, 8763.
  mla: King, Daniel S., et al. “Machine Learning of Charges and Long-Range Interactions
    from Energies and Forces.” <i>Nature Communications</i>, vol. 16, 8763, Springer
    Nature, 2025, doi:<a href="https://doi.org/10.1038/s41467-025-63852-x">10.1038/s41467-025-63852-x</a>.
  short: D.S. King, D. Kim, P. Zhong, B. Cheng, Nature Communications 16 (2025).
corr_author: '1'
date_created: 2025-10-12T22:01:25Z
date_published: 2025-10-01T00:00:00Z
date_updated: 2026-02-16T12:21:50Z
day: '01'
ddc:
- '000'
department:
- _id: BiCh
doi: 10.1038/s41467-025-63852-x
external_id:
  isi:
  - '001586620700015'
  pmid:
  - '41034200'
file:
- access_level: open_access
  checksum: 34b6005d349bbff85839c4e51d6c8725
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T07:54:51Z
  date_updated: 2025-10-13T07:54:51Z
  file_id: '20460'
  file_name: 2025_NatureComm_King.pdf
  file_size: 4907055
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  success: 1
file_date_updated: 2025-10-13T07:54:51Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Machine learning of charges and long-range interactions from energies and forces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20453'
abstract:
- lang: eng
  text: 'Magnetotropic susceptibility is the thermodynamic coefficient that maps the
    curvature of free energy with respect to an applied magnetic field orientation,
    providing a means to quantify the magnetic anisotropy of a crystal. In this context,
    non-linear magnetic torque behavior has been reported in FePS3, motivating the
    investigation of similar non-linear characteristics in its magnetotropic susceptibility.
    In this work, we derive the non-linear magnetotropic susceptibility expressions
    for FePS3 in both ac*-and bc*-planes using complementary approaches: by taking
    the first derivative of torque and through the formal calculation of the magnetotropic
    susceptibility. Higher-order terms in the magnetization are included, and the
    final equations are obtained by applying symmetry constraints imposed by the C2h
    point group of the material. We analyze the behavior of the resulting non-linear
    expressions and identify the contributions of each parameter. Our theoretical
    results show good agreement with preliminary, unpublished experimental data, offering
    meaningful guidance for ongoing and future experimental work.'
acknowledgement: We thank Kimberly A. Modic for her support and discussions regarding
  the technique in the context of a project indirectly related to, but distinct from,
  the present work. We also thank Brad J. Ramshaw and Arkady Shekhter for scientific
  discussions not directly related to this study, but whose insights proved helpful.
  We are grateful to Valeska Zambra, Amit Nathwani, Hamza Nasir, and Tayyaba Hussain
  for informal discussions on various aspects of the technique, and to Naoya Iwahara
  for his thoughtful and constructive feedback. The experimental curve shown in figures
  3(b) and 6, from the Thermodynamics of Quantum Materials (TQM) group at ISTA, was
  measured by Muhammad Nauman for an unrelated project. We thank Kimberly Modic for
  granting access to the laboratory facilities. Je Geun Park provided the crystal
  used for that measurement via Younjung Jo, whose contribution we gratefully acknowledge.
  Institutional support from the Institute of Science and Technology Austria (ISTA)
  is also gratefully acknowledged.
article_number: '405801'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Hamza
  full_name: Farooq, Hamza
  last_name: Farooq
- first_name: Muhammad
  full_name: Nauman, Muhammad
  id: 32c21954-2022-11eb-9d5f-af9f93c24e71
  last_name: Nauman
  orcid: 0000-0002-2111-4846
citation:
  ama: Farooq H, Nauman M. Non-linear magnetotropic susceptibility in FePS3. <i>Journal
    of Physics Condensed Matter</i>. 2025;37(40). doi:<a href="https://doi.org/10.1088/1361-648X/ae0913">10.1088/1361-648X/ae0913</a>
  apa: Farooq, H., &#38; Nauman, M. (2025). Non-linear magnetotropic susceptibility
    in FePS3. <i>Journal of Physics Condensed Matter</i>. IOP Publishing. <a href="https://doi.org/10.1088/1361-648X/ae0913">https://doi.org/10.1088/1361-648X/ae0913</a>
  chicago: Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility
    in FePS3.” <i>Journal of Physics Condensed Matter</i>. IOP Publishing, 2025. <a
    href="https://doi.org/10.1088/1361-648X/ae0913">https://doi.org/10.1088/1361-648X/ae0913</a>.
  ieee: H. Farooq and M. Nauman, “Non-linear magnetotropic susceptibility in FePS3,”
    <i>Journal of Physics Condensed Matter</i>, vol. 37, no. 40. IOP Publishing, 2025.
  ista: Farooq H, Nauman M. 2025. Non-linear magnetotropic susceptibility in FePS3.
    Journal of Physics Condensed Matter. 37(40), 405801.
  mla: Farooq, Hamza, and Muhammad Nauman. “Non-Linear Magnetotropic Susceptibility
    in FePS3.” <i>Journal of Physics Condensed Matter</i>, vol. 37, no. 40, 405801,
    IOP Publishing, 2025, doi:<a href="https://doi.org/10.1088/1361-648X/ae0913">10.1088/1361-648X/ae0913</a>.
  short: H. Farooq, M. Nauman, Journal of Physics Condensed Matter 37 (2025).
corr_author: '1'
date_created: 2025-10-12T22:01:26Z
date_published: 2025-10-06T00:00:00Z
date_updated: 2025-12-01T12:43:33Z
day: '06'
ddc:
- '530'
department:
- _id: KiMo
doi: 10.1088/1361-648X/ae0913
external_id:
  isi:
  - '001585824100001'
  pmid:
  - '40967257'
file:
- access_level: open_access
  checksum: b182856a5a655496e149afa49ec464f3
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T06:34:15Z
  date_updated: 2025-10-13T06:34:15Z
  file_id: '20458'
  file_name: 2025_JourPhysicsCondMatter_Farooq.pdf
  file_size: 1709516
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T06:34:15Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '40'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Physics Condensed Matter
publication_identifier:
  eissn:
  - 1361-648X
  issn:
  - 0953-8984
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-linear magnetotropic susceptibility in FePS3
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2025'
...
---
OA_place: publisher
OA_type: diamond
PlanS_conform: '1'
_id: '20454'
abstract:
- lang: eng
  text: "Context. γ Dor stars are ideal targets for studies of the innermost dynamical
    properties of stars, due to their rich asteroseismic spectrum of gravity modes.
    Integrating internal magnetism to the picture appears as the next milestone of
    detailed asteroseismic studies, for its prime importance on stellar evolution.
    The inertial dip in prograde dipole modes period-spacing pattern of γ Dors stands
    out as a unique window on the convective core structure and dynamics. Recent studies
    have highlighted the dependence of the dip structure on core density stratification,
    the contrast of the near-core Brunt-Väisälä frequency and rotation rate, as well
    as the core-to-near-core differential rotation. In addition, the effect of envelope
    magnetism has been derived on low-frequency magneto-gravito-inertial waves.\r\n\r\nAims.
    We revisited the inertial dip formation including core and envelope magnetism,
    and explored the probing power of this feature on dynamo-generated core fields.\r\n\r\nMethods.
    We considered as a first step a toroidal magnetic field with a bi-layer (core
    and envelope) Alfvén frequency. This configuration allowed us to revisit the coupling
    problem using our knowledge on both core magneto-inertial modes and envelope magneto-gravito-inertial
    modes. Using this configuration, we were able to stay in an analytical framework
    to exhibit the magnetic effects on the inertial dip shape and location. This configuration
    allowed a laboratory to be set up that moves us towards the comprehension of magnetic
    effects on the dip structure.\r\n\r\nResults. We show a shift of the inertial
    dip towards lower spin parameter values and a thinner dip with increasing core
    magnetic field’s strength, quite similar to the signature of differential rotation.
    The magnetic effects become sizeable when the ratio of the magnetic to the Coriolis
    effects is high enough. We explored the potential degeneracy of the magnetic effects
    with differential rotation. We studied the detectability of core magnetism, considering
    both observational constraints on the periods of the modes and potential gravito-inertial
    mode suppression."
acknowledgement: 'We thank the referee for their comments and suggestions which allowed
  us to improve the quality of this manuscript. L. Barrault and L. Bugnet gratefully
  acknowledge support from the European Research Council (ERC) under the Horizon Europe
  programme (Calcifer; Starting Grant agreement N°101165631). S. Mathis acknowledges
  support from the PLATO CNES grant at CEA/DAp. S. Mathis and J.S.G. Mombarg acknowledge
  support from the European Research Council through HORIZON ERC SyG Grant 4D-STAR
  101071505. While partially funded by the European Union, views and opinions expressed
  are however those of the authors only and do not necessarily reflect those of the
  European Union or the European Research Council. Neither the European Union nor
  the granting authority can be held responsible for them. L. Barrault thanks T. Van
  Reeth and C. Aerts for their invaluable teachings. The authors thank also the members
  of the Asteroseismology and Stellar Dynamics group of the Institute of Science and
  Technology Austria (ISTA) for very useful discussion: A. Cristea, L. Einramhof,
  K. M. Smith, S. Torres.'
article_number: A253
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Lucas
  full_name: Barrault, Lucas
  id: 4471a8fd-32c1-11ee-a9a4-fb670d398f64
  last_name: Barrault
- first_name: Lisa Annabelle
  full_name: Bugnet, Lisa Annabelle
  id: d9edb345-f866-11ec-9b37-d119b5234501
  last_name: Bugnet
  orcid: 0000-0003-0142-4000
- first_name: S.
  full_name: Mathis, S.
  last_name: Mathis
- first_name: J. S.G.
  full_name: Mombarg, J. S.G.
  last_name: Mombarg
citation:
  ama: 'Barrault L, Bugnet LA, Mathis S, Mombarg JSG. Exploring the probing power
    of γ Dor’s inertial dip for core magnetism: The case of a toroidal field. <i>Astronomy
    &#38; Astrophysics</i>. 2025;701. doi:<a href="https://doi.org/10.1051/0004-6361/202555213">10.1051/0004-6361/202555213</a>'
  apa: 'Barrault, L., Bugnet, L. A., Mathis, S., &#38; Mombarg, J. S. G. (2025). Exploring
    the probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal
    field. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href="https://doi.org/10.1051/0004-6361/202555213">https://doi.org/10.1051/0004-6361/202555213</a>'
  chicago: 'Barrault, Lucas, Lisa Annabelle Bugnet, S. Mathis, and J. S.G. Mombarg.
    “Exploring the Probing Power of γ Dor’s Inertial Dip for Core Magnetism: The Case
    of a Toroidal Field.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2025.
    <a href="https://doi.org/10.1051/0004-6361/202555213">https://doi.org/10.1051/0004-6361/202555213</a>.'
  ieee: 'L. Barrault, L. A. Bugnet, S. Mathis, and J. S. G. Mombarg, “Exploring the
    probing power of γ Dor’s inertial dip for core magnetism: The case of a toroidal
    field,” <i>Astronomy &#38; Astrophysics</i>, vol. 701. EDP Sciences, 2025.'
  ista: 'Barrault L, Bugnet LA, Mathis S, Mombarg JSG. 2025. Exploring the probing
    power of γ Dor’s inertial dip for core magnetism: The case of a toroidal field.
    Astronomy &#38; Astrophysics. 701, A253.'
  mla: 'Barrault, Lucas, et al. “Exploring the Probing Power of γ Dor’s Inertial Dip
    for Core Magnetism: The Case of a Toroidal Field.” <i>Astronomy &#38; Astrophysics</i>,
    vol. 701, A253, EDP Sciences, 2025, doi:<a href="https://doi.org/10.1051/0004-6361/202555213">10.1051/0004-6361/202555213</a>.'
  short: L. Barrault, L.A. Bugnet, S. Mathis, J.S.G. Mombarg, Astronomy &#38; Astrophysics
    701 (2025).
corr_author: '1'
date_created: 2025-10-12T22:01:26Z
date_published: 2025-09-01T00:00:00Z
date_updated: 2026-02-19T09:32:04Z
day: '01'
ddc:
- '520'
department:
- _id: LiBu
- _id: GradSch
doi: 10.1051/0004-6361/202555213
external_id:
  arxiv:
  - '2507.00308'
  isi:
  - '001585834500002'
file:
- access_level: open_access
  checksum: 2c209b33119af4a251bab4a418a21075
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-13T07:05:55Z
  date_updated: 2025-10-13T07:05:55Z
  file_id: '20459'
  file_name: 2025_AstronomyAstrophysics_BarraultL.pdf
  file_size: 2503149
  relation: main_file
  success: 1
file_date_updated: 2025-10-13T07:05:55Z
has_accepted_license: '1'
intvolume: '       701'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 914d8549-16d5-11f0-9cad-bbe6324c93a9
  grant_number: '101165631'
  name: 'Unveiling the mysteries of stellar dynamics: a pioneering journey in magnetoasteroseismology'
publication: Astronomy & Astrophysics
publication_identifier:
  eissn:
  - 1432-0746
  issn:
  - 0004-6361
publication_status: published
publisher: EDP Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Exploring the probing power of γ Dor''s inertial dip for core magnetism: The
  case of a toroidal field'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 701
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '20455'
abstract:
- lang: eng
  text: Despite extensive research since the community learned about adversarial examples
    10 years ago, we still do not know how to train high-accuracy classifiers that
    are guaranteed to be robust to small perturbations of their inputs. Previous works
    often argued that this might be because no classifier exists that is robust and
    accurate at the same time. However, in computer vision this assumption does not
    match reality where humans are usually accurate and robust on most tasks of interest.
    We offer an alternative explanation and show that in certain settings robust generalization
    is only possible with unrealistically large amounts of data. Specifically, we
    find a setting where a robust classifier exists, it is easy to learn an accurate
    classifier, yet it requires an exponential amount of data to learn a robust classifier.
    Based on this theoretical result, we evaluate the influence of the amount of training
    data on datasets such as CIFAR10. Our findings indicate that the the amount of
    training data is the main factor determining the robust performance. Furthermore
    we show that that there are low magnitude directions in the data which are useful
    for non-robust generalization but are not available for robust classifiers. This
    implies that robust classification is a strictly harder tasks than normal classification,
    thereby providing an explanation why robust classification requires more data.
article_processing_charge: No
arxiv: 1
author:
- first_name: Bernd
  full_name: Prach, Bernd
  id: 2D561D42-C427-11E9-89B4-9C1AE6697425
  last_name: Prach
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: 'Prach B, Lampert C. Intriguing properties of robust classification. In: <i>2025
    IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>.
    IEEE; 2025:660-669. doi:<a href="https://doi.org/10.1109/CVPRW67362.2025.00071">10.1109/CVPRW67362.2025.00071</a>'
  apa: 'Prach, B., &#38; Lampert, C. (2025). Intriguing properties of robust classification.
    In <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>
    (pp. 660–669). Nashville, TN, United States: IEEE. <a href="https://doi.org/10.1109/CVPRW67362.2025.00071">https://doi.org/10.1109/CVPRW67362.2025.00071</a>'
  chicago: Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.”
    In <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>,
    660–69. IEEE, 2025. <a href="https://doi.org/10.1109/CVPRW67362.2025.00071">https://doi.org/10.1109/CVPRW67362.2025.00071</a>.
  ieee: B. Prach and C. Lampert, “Intriguing properties of robust classification,”
    in <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>,
    Nashville, TN, United States, 2025, pp. 660–669.
  ista: 'Prach B, Lampert C. 2025. Intriguing properties of robust classification.
    2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops.
    CVPR: Conference on Computer Vision and Pattern Recognition, 660–669.'
  mla: Prach, Bernd, and Christoph Lampert. “Intriguing Properties of Robust Classification.”
    <i>2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops</i>,
    IEEE, 2025, pp. 660–69, doi:<a href="https://doi.org/10.1109/CVPRW67362.2025.00071">10.1109/CVPRW67362.2025.00071</a>.
  short: B. Prach, C. Lampert, in:, 2025 IEEE/CVF Conference on Computer Vision and
    Pattern Recognition Workshops, IEEE, 2025, pp. 660–669.
conference:
  end_date: 2025-06-12
  location: Nashville, TN, United States
  name: 'CVPR: Conference on Computer Vision and Pattern Recognition'
  start_date: 2025-06-11
corr_author: '1'
date_created: 2025-10-12T22:01:26Z
date_published: 2025-06-15T00:00:00Z
date_updated: 2025-10-13T07:18:26Z
day: '15'
department:
- _id: ChLa
doi: 10.1109/CVPRW67362.2025.00071
external_id:
  arxiv:
  - '2412.04245'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2412.04245
month: '06'
oa: 1
oa_version: Preprint
page: 660-669
publication: 2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops
publication_identifier:
  eissn:
  - 2160-7516
  isbn:
  - '9798331599942'
  issn:
  - 2160-7508
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '18874'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Intriguing properties of robust classification
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20457'
abstract:
- lang: eng
  text: Patch-clamp recording of miniature postsynaptic currents (mPSCs, or ‘minis’)
    is used extensively to investigate the functional properties of synapses. With
    this approach, spontaneous synaptic transmission events are recorded in an attempt
    to determine quantal synaptic parameters or the effect of synaptic manipulations.
    However, at the majority of brain synapses these events are small, with many undetectable
    due to recording noise. The effects of incomplete detection were well appreciated
    in the early years of synaptic physiology analysis, but appear to be increasingly
    forgotten. Here we sought to characterise the consequences of incomplete detection
    on the interpretability of mini analysis, using simulated mPSC data to give full
    control over event parameters. We demonstrate that commonly reported measures
    such as mean event amplitude and frequency, are misrepresented by the loss of
    undetected events. Probabilistic loss of small events results in detected event
    amplitude distributions that appear biologically complete, yet do not reflect
    the underlying synaptic properties. With both simulated and experimental datasets,
    we demonstrate that specific changes in event amplitude are primarily detected
    as changes in frequency, compromising classical biological interpretations. To
    facilitate more robust data analysis and interpretation, we detail a means for
    experimental estimation of the event detection limit and provide practical recommendations
    for data analysis. Together, our study highlights how mini analysis is prone to
    falsely reporting synaptic changes, raising awareness of these considerations,
    and provides a framework for more robust data analysis and interpretation.
acknowledgement: This work was supported by Biological Services teams at both the
  Laboratory of Molecular Biology and Ares facilities. The authors are very grateful
  to Prof. Helmut Kessels and Dr. Hinze Ho for initial discussions that led to this
  study, Dr. Andrew Penn for constructive feedback on the project, Xinyao Dou for
  comments on the study, and Profs. Peter Jonas and Roger Nicoll for feedback on the
  manuscript. Funding was provided by the Medical Research Council (MRC – MC_U105174197
  to I.H.G.) and the European Union's Horizon 2020 programme through a Marie Skłodowska-Curie
  Actions Individual Fellowship (MSCA-IF 101026635 to J.F.W.).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Ingo H.
  full_name: Greger, Ingo H.
  last_name: Greger
- first_name: Jake
  full_name: Watson, Jake
  id: 63836096-4690-11EA-BD4E-32803DDC885E
  last_name: Watson
  orcid: 0000-0002-8698-3823
citation:
  ama: Greger IH, Watson J. ‘Mini analysis’ misrepresents changes in synaptic properties
    due to incomplete event detection. <i>Journal of Physiology</i>. 2025;603(22):7189-7205.
    doi:<a href="https://doi.org/10.1113/JP288183">10.1113/JP288183</a>
  apa: Greger, I. H., &#38; Watson, J. (2025). ‘Mini analysis’ misrepresents changes
    in synaptic properties due to incomplete event detection. <i>Journal of Physiology</i>.
    Wiley. <a href="https://doi.org/10.1113/JP288183">https://doi.org/10.1113/JP288183</a>
  chicago: Greger, Ingo H., and Jake Watson. “‘Mini Analysis’ Misrepresents Changes
    in Synaptic Properties Due to Incomplete Event Detection.” <i>Journal of Physiology</i>.
    Wiley, 2025. <a href="https://doi.org/10.1113/JP288183">https://doi.org/10.1113/JP288183</a>.
  ieee: I. H. Greger and J. Watson, “‘Mini analysis’ misrepresents changes in synaptic
    properties due to incomplete event detection,” <i>Journal of Physiology</i>, vol.
    603, no. 22. Wiley, pp. 7189–7205, 2025.
  ista: Greger IH, Watson J. 2025. ‘Mini analysis’ misrepresents changes in synaptic
    properties due to incomplete event detection. Journal of Physiology. 603(22),
    7189–7205.
  mla: Greger, Ingo H., and Jake Watson. “‘Mini Analysis’ Misrepresents Changes in
    Synaptic Properties Due to Incomplete Event Detection.” <i>Journal of Physiology</i>,
    vol. 603, no. 22, Wiley, 2025, pp. 7189–205, doi:<a href="https://doi.org/10.1113/JP288183">10.1113/JP288183</a>.
  short: I.H. Greger, J. Watson, Journal of Physiology 603 (2025) 7189–7205.
corr_author: '1'
date_created: 2025-10-12T22:01:27Z
date_published: 2025-11-15T00:00:00Z
date_updated: 2026-01-05T13:13:32Z
day: '15'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1113/JP288183
ec_funded: 1
external_id:
  isi:
  - '001581924700001'
  pmid:
  - '41015537'
file:
- access_level: open_access
  checksum: 3326e49795f44a7c51c16ecbcce58cde
  content_type: application/pdf
  creator: dernst
  date_created: 2026-01-05T13:13:06Z
  date_updated: 2026-01-05T13:13:06Z
  file_id: '20949'
  file_name: 2025_JourPhysiology_Greger.pdf
  file_size: 10875254
  relation: main_file
  success: 1
file_date_updated: 2026-01-05T13:13:06Z
has_accepted_license: '1'
intvolume: '       603'
isi: 1
issue: '22'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 7189-7205
pmid: 1
project:
- _id: fc2be41b-9c52-11eb-aca3-faa90aa144e9
  call_identifier: H2020
  grant_number: '101026635'
  name: Synaptic computations of the hippocampal CA3 circuitry
publication: Journal of Physiology
publication_identifier:
  eissn:
  - 1469-7793
  issn:
  - 0022-3751
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/jakefwatson/miniplace
scopus_import: '1'
status: public
title: ‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete
  event detection
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 603
year: '2025'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '20477'
abstract:
- lang: eng
  text: An electric double-layer capacitor (EDLC) stores energy by modulating the
    spatial distribution of ions in the electrolytic solution that it contains. We
    determine the mean-field timescales for planar EDLC relaxation to equilibrium
    after a potential difference is applied. We tackle first the fully symmetric case,
    where positive and negative ionic species have the same valence and diffusivity,
    and then the general, more complex, asymmetric case. Depending on the applied
    voltage and salt concentration, different regimes appear, revealing a remarkably
    rich phenomenology relevant for nanocapacitors.
acknowledgement: This work has received funding from the European Union’s Horizon
  2020 and Horizon Europe research and innovation programs under the Marie Skłodowska-Curie
  Grants No. 674979-NANOTRANS (I. P., P. B. W., B. R., E. T.), No. 101034413 (I. P.),
  and No. 101119598-FLUXIONIC (M. D., B. R., E. T.), as well as from the European
  Research Council under Grant No. 863473 (B. R.). B. R. acknowledges financial support
  from the French Agence Nationale de la Recherche (ANR) under Grant No. ANR-21-CE29-0021-02
  (DIADEM). I. P. thanks Anđela Šarić for further support at ISTA.
article_number: '148002'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Ivan
  full_name: Palaia, Ivan
  id: 9c805cd2-4b75-11ec-a374-db6dd0ed57fa
  last_name: Palaia
  orcid: ' 0000-0002-8843-9485 '
- first_name: Adelchi J.
  full_name: Asta, Adelchi J.
  last_name: Asta
- first_name: Megh
  full_name: Dutta, Megh
  last_name: Dutta
- first_name: Patrick B.
  full_name: Warren, Patrick B.
  last_name: Warren
- first_name: Benjamin
  full_name: Rotenberg, Benjamin
  last_name: Rotenberg
- first_name: Emmanuel
  full_name: Trizac, Emmanuel
  last_name: Trizac
citation:
  ama: Palaia I, Asta AJ, Dutta M, Warren PB, Rotenberg B, Trizac E. Charging dynamics
    of electric double-layer nanocapacitors in mean field. <i>Physical Review Letters</i>.
    2025;135(14). doi:<a href="https://doi.org/10.1103/72b9-c8cq">10.1103/72b9-c8cq</a>
  apa: Palaia, I., Asta, A. J., Dutta, M., Warren, P. B., Rotenberg, B., &#38; Trizac,
    E. (2025). Charging dynamics of electric double-layer nanocapacitors in mean field.
    <i>Physical Review Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/72b9-c8cq">https://doi.org/10.1103/72b9-c8cq</a>
  chicago: Palaia, Ivan, Adelchi J. Asta, Megh Dutta, Patrick B. Warren, Benjamin
    Rotenberg, and Emmanuel Trizac. “Charging Dynamics of Electric Double-Layer Nanocapacitors
    in Mean Field.” <i>Physical Review Letters</i>. American Physical Society, 2025.
    <a href="https://doi.org/10.1103/72b9-c8cq">https://doi.org/10.1103/72b9-c8cq</a>.
  ieee: I. Palaia, A. J. Asta, M. Dutta, P. B. Warren, B. Rotenberg, and E. Trizac,
    “Charging dynamics of electric double-layer nanocapacitors in mean field,” <i>Physical
    Review Letters</i>, vol. 135, no. 14. American Physical Society, 2025.
  ista: Palaia I, Asta AJ, Dutta M, Warren PB, Rotenberg B, Trizac E. 2025. Charging
    dynamics of electric double-layer nanocapacitors in mean field. Physical Review
    Letters. 135(14), 148002.
  mla: Palaia, Ivan, et al. “Charging Dynamics of Electric Double-Layer Nanocapacitors
    in Mean Field.” <i>Physical Review Letters</i>, vol. 135, no. 14, 148002, American
    Physical Society, 2025, doi:<a href="https://doi.org/10.1103/72b9-c8cq">10.1103/72b9-c8cq</a>.
  short: I. Palaia, A.J. Asta, M. Dutta, P.B. Warren, B. Rotenberg, E. Trizac, Physical
    Review Letters 135 (2025).
corr_author: '1'
date_created: 2025-10-16T13:09:30Z
date_published: 2025-09-29T00:00:00Z
date_updated: 2025-12-01T15:02:16Z
day: '29'
ddc:
- '530'
department:
- _id: AnSa
doi: 10.1103/72b9-c8cq
ec_funded: 1
external_id:
  arxiv:
  - '2301.00610'
  isi:
  - '001587121300010'
file:
- access_level: open_access
  checksum: e29809fea48b18217d1779980f7117c4
  content_type: application/pdf
  creator: dernst
  date_created: 2025-10-23T11:57:20Z
  date_updated: 2025-10-23T11:57:20Z
  file_id: '20526'
  file_name: 2025_PhysReviewLetters_Palaia.pdf
  file_size: 480414
  relation: main_file
  success: 1
file_date_updated: 2025-10-23T11:57:20Z
has_accepted_license: '1'
intvolume: '       135'
isi: 1
issue: '14'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Charging dynamics of electric double-layer nanocapacitors in mean field
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 135
year: '2025'
...
