--- _id: '21145' abstract: - lang: eng text: 'Protein conformational energy landscapes are shaped not only by intramolecular interactions but also by their environment. In protein crystals and protein-protein complexes, intermolecular contacts alter this energy landscape, but the exact nature of this alteration is difficult to decipher. Understanding how the crystal lattice affects protein dynamics is crucial for crystallography-based studies of motion, yet its influence on collective motions remains unclear. Aromatic ring flips in the hydrophobic core represent sensitive probes of such dynamics. Here, we compare the kinetics of aromatic ring flips in the protein GB1 in crystals, in complex with its binding partner IgG, and in solution, combining advanced isotope labeling with quantitative NMR methods. We show that rings in the core flip nearly a thousand times less frequently in crystals than in solution. Enhanced-sampling molecular dynamics simulations, based on a new crystal structure, reproduce these elevated barriers and reveal how the crystal restrains motions. ' acknowledged_ssus: - _id: NMR - _id: LifeSc acknowledgement: "We thank Nikolai R. Skrynnikov and Olga O. Lebedenko (St. Petersburg) for insightful discussions and for performing exploratory MD simulations. We are grateful to Tobias Schubeis (Lyon) for advice with GB1 crystallization, and Rebecca Schmid for initial crystallization trials.\r\nWe thank Sebastian Falkner for assistance with constructing the structural model of the IgG:GB1 complex.\r\nThis research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance and the Lab Support Facilities. We thank Petra Rovó and Margarita Valhondo Falcón for excellent support of the NMR facility.\r\nLea M. Becker is recipient of a DOC fellowship of the Austrian Academy of Sciences at the Institute of Science and Technology Austria (grant no. PR10660EAW01). Christophe Chipot acknowledges the European Research Council (grant project 101097272 ``MilliInMicro'') and the Métropole du Grand Nancy (grant project ``ARC''). BM07-FIP2 is supported by the French ANR PIA3 (France 2030) EquipEx+ project MAGNIFIX under grant agreement ANR-21-ESRE-0011." article_processing_charge: No author: - first_name: Lea Marie full_name: Becker, Lea Marie id: 36336939-eb97-11eb-a6c2-c83f1214ca79 last_name: Becker orcid: 0000-0002-6401-5151 - first_name: Paul full_name: Schanda, Paul id: 7B541462-FAF6-11E9-A490-E8DFE5697425 last_name: Schanda orcid: 0000-0002-9350-7606 - first_name: Christophe full_name: Chipot, Christophe last_name: Chipot citation: ama: Becker LM, Schanda P, Chipot C. Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” 2026. doi:10.15479/AT-ISTA-21145 apa: Becker, L. M., Schanda, P., & Chipot, C. (2026). Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21145 chicago: Becker, Lea Marie, Paul Schanda, and Christophe Chipot. “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21145. ieee: L. M. Becker, P. Schanda, and C. Chipot, “Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.’” Institute of Science and Technology Austria, 2026. ista: Becker LM, Schanda P, Chipot C. 2026. Additional Data for ‘Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21145. mla: Becker, Lea Marie, et al. Additional Data for “Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21145. short: L.M. Becker, P. Schanda, C. Chipot, (2026). contributor: - contributor_type: researcher first_name: Haohao last_name: Fu - contributor_type: researcher first_name: Benjamin id: 71cda2f3-e604-11ee-a1df-da10587eda3f last_name: Tatman - contributor_type: researcher first_name: Matthias last_name: Dreydoppel - contributor_type: researcher first_name: Anna id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471 last_name: Kapitonova - contributor_type: researcher first_name: Daniel id: 302BADF6-85FC-11EA-9E3B-B9493DDC885E last_name: Balazs orcid: 0000-0001-7597-043X - contributor_type: researcher first_name: Ulrich last_name: Weininger - contributor_type: researcher first_name: Sylvain last_name: Engilberge corr_author: '1' date_created: 2026-02-05T13:54:39Z date_published: 2026-02-09T00:00:00Z date_updated: 2026-02-18T10:04:44Z day: '09' ddc: - '572' department: - _id: GradSch - _id: PaSc doi: 10.15479/AT-ISTA-21145 file: - access_level: open_access checksum: 02a419cce8cea450bc952f35488d2df5 content_type: text/plain creator: lbecker date_created: 2026-02-05T13:52:37Z date_updated: 2026-02-05T13:52:37Z file_id: '21146' file_name: README.txt file_size: 4263 relation: table_of_contents - access_level: open_access checksum: b0b82b1aa73985b0b308a3fa52d21aea content_type: application/zip creator: lbecker date_created: 2026-02-05T13:52:41Z date_updated: 2026-02-05T13:52:41Z file_id: '21147' file_name: Research_Data.zip file_size: 50647107 relation: main_file success: 1 file_date_updated: 2026-02-05T13:52:41Z has_accepted_license: '1' month: '02' oa: 1 oa_version: Published Version project: - _id: 7be609c4-9f16-11ee-852c-85015ce2b9b0 grant_number: '26777' name: Exploring protein dynamics by solid-state MAS NMR through specific labeling approaches publisher: Institute of Science and Technology Austria related_material: record: - id: '20641' relation: earlier_version status: public status: public title: Additional Data for "Aromatic Ring Flips Reveal Reshaping of Protein Dynamics in Crystals and Complexes" tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: research_data user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '21149' abstract: - lang: eng text: We present a general theoretical framework for helical dichroism (HD), establishing an explicit link between chiral resolution and orbital angular momentum (OAM) exchange in light–matter interaction. Tracing microscopic mechanisms of the OAM transfer, we derive rotational selection rules, which establish that HD emerges only from the spin–orbit coupling of light, even for beams without the far-field OAM. Our findings refine the conditions for observing HD, provide a tool to re-examine the outcome of prior experiments, and guide future designs for chiral sensing with structured light. acknowledgement: This research was funded in whole or in part by the Austrian Science Fund (FWF) [10.55776/F1004]. article_number: '053204' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Mateja full_name: Hrast, Mateja id: 48dbb294-2a9c-11ef-905d-f56be71f0e5d last_name: Hrast - first_name: Georgios full_name: Koutentakis, Georgios id: d7b23d3a-9e21-11ec-b482-f76739596b95 last_name: Koutentakis - first_name: Mikhail full_name: Maslov, Mikhail id: 2E65BB0E-F248-11E8-B48F-1D18A9856A87 last_name: Maslov orcid: 0000-0003-4074-2570 - first_name: Mikhail full_name: Lemeshko, Mikhail id: 37CB05FA-F248-11E8-B48F-1D18A9856A87 last_name: Lemeshko orcid: 0000-0002-6990-7802 citation: ama: Hrast M, Koutentakis G, Maslov M, Lemeshko M. Bottom-up analysis of rovibrational helical dichroism. Physical Review Letters. 2026;136(5). doi:10.1103/fkf1-1jml apa: Hrast, M., Koutentakis, G., Maslov, M., & Lemeshko, M. (2026). Bottom-up analysis of rovibrational helical dichroism. Physical Review Letters. American Physical Society. https://doi.org/10.1103/fkf1-1jml chicago: Hrast, Mateja, Georgios Koutentakis, Mikhail Maslov, and Mikhail Lemeshko. “Bottom-up Analysis of Rovibrational Helical Dichroism.” Physical Review Letters. American Physical Society, 2026. https://doi.org/10.1103/fkf1-1jml. ieee: M. Hrast, G. Koutentakis, M. Maslov, and M. Lemeshko, “Bottom-up analysis of rovibrational helical dichroism,” Physical Review Letters, vol. 136, no. 5. American Physical Society, 2026. ista: Hrast M, Koutentakis G, Maslov M, Lemeshko M. 2026. Bottom-up analysis of rovibrational helical dichroism. Physical Review Letters. 136(5), 053204. mla: Hrast, Mateja, et al. “Bottom-up Analysis of Rovibrational Helical Dichroism.” Physical Review Letters, vol. 136, no. 5, 053204, American Physical Society, 2026, doi:10.1103/fkf1-1jml. short: M. Hrast, G. Koutentakis, M. Maslov, M. Lemeshko, Physical Review Letters 136 (2026). corr_author: '1' date_created: 2026-02-06T10:53:17Z date_published: 2026-02-05T00:00:00Z date_updated: 2026-02-10T11:30:37Z day: '05' ddc: - '530' department: - _id: MiLe doi: 10.1103/fkf1-1jml external_id: arxiv: - '2505.16393' file: - access_level: open_access checksum: 805c929fff9fd4d0e733293eaace67b8 content_type: application/pdf creator: dernst date_created: 2026-02-10T11:25:46Z date_updated: 2026-02-10T11:25:46Z file_id: '21210' file_name: 2026_PhysicalReviewLetters_Hrast.pdf file_size: 511312 relation: main_file success: 1 file_date_updated: 2026-02-10T11:25:46Z has_accepted_license: '1' intvolume: ' 136' issue: '5' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ month: '02' oa: 1 oa_version: Published Version project: - _id: 7c040762-9f16-11ee-852c-dd79eeee4ab3 grant_number: F100403 name: Coherent Optical Metrology Beyond Electric-Dipole-Allowed Transitions publication: Physical Review Letters publication_identifier: eissn: - 1079-7114 issn: - 0031-9007 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: Bottom-up analysis of rovibrational helical dichroism tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 136 year: '2026' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '21158' abstract: - lang: eng text: Vernalization-regulated flowering is vital for wheat yield and geographical distribution, and the diversity of flowering time genes is essential for the breeding of climate-resilient varieties. Sugars have long been recognized in regulating flowering; however, the intrinsic connection between carbohydrate metabolism and vernalization response remains largely unexplored. Here, we identify a fructose 1,6-bisphosphate aldolase (FBA) encoding gene, HtL1/FBA10, as a modulator of heading time variation based on a genome-wide association study utilizing wheat core germplasm collections. Evolutionary analysis shows a decrease in the proportion of haplotype-2 of HtL1, which is linked to delayed flowering, in Chinese and American wheat varieties compared to landraces. Vernalization reduces HtL1/FBA10 phosphorylation levels and increases its O-GlcNAcylation, which in turn enhances its enzymatic activity and facilitates VERNALIZATION 1 (VRN1) transcription by regulating histone acetylation at the VRN1 locus. Our findings provide mechanistic insights into the interplay between glucose metabolism and the epigenetic regulation of vernalization in winter wheat. acknowledgement: This work was supported by the Basic Science Center Project of National Natural Science Foundation of China (32388201) to K.C and the National Natural Science Foundation of China (31970331) to L.X. We thank Dr. Zhuang Lu, Dr. Bin Han and Ms. Jingquan Li (Plant Science Facility of the Institute of Botany, Chinese Academy of Sciences) for their technical assistance in LC-MS/MS assay, small molecule compound analysis and the subcellular localization assay, respectively. We thank Dr. Wei Luo and Dr. Dongfeng Liu for helpful discussions. article_number: '999' article_processing_charge: Yes article_type: original author: - first_name: Pengfang full_name: Yang, Pengfang last_name: Yang - first_name: Yangyang full_name: Liu, Yangyang last_name: Liu - first_name: Qi full_name: Dong, Qi last_name: Dong - first_name: Yuting full_name: Miao, Yuting last_name: Miao - first_name: Jianlong full_name: Zhang, Jianlong last_name: Zhang - first_name: Shujuan full_name: Xu, Shujuan id: 9724dd9d-f591-11ee-bd51-e97ed0652286 last_name: Xu - first_name: Hong full_name: Zhao, Hong last_name: Zhao - first_name: Yuda full_name: Niu, Yuda last_name: Niu - first_name: Xueyong full_name: Zhang, Xueyong last_name: Zhang - first_name: Yunyuan full_name: Xu, Yunyuan last_name: Xu - first_name: Zifeng full_name: Guo, Zifeng last_name: Guo - first_name: Lijing full_name: Xing, Lijing last_name: Xing - first_name: Kang full_name: Chong, Kang last_name: Chong citation: ama: Yang P, Liu Y, Dong Q, et al. O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. Nature Communications. 2026;17. doi:10.1038/s41467-025-67734-0 apa: Yang, P., Liu, Y., Dong, Q., Miao, Y., Zhang, J., Xu, S., … Chong, K. (2026). O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-025-67734-0 chicago: Yang, Pengfang, Yangyang Liu, Qi Dong, Yuting Miao, Jianlong Zhang, Shujuan Xu, Hong Zhao, et al. “O-GlcNAc and Phosphorylation Modifications on HtL1/FBA10 Regulate Wheat Vernalization for Flowering.” Nature Communications. Springer Nature, 2026. https://doi.org/10.1038/s41467-025-67734-0. ieee: P. Yang et al., “O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering,” Nature Communications, vol. 17. Springer Nature, 2026. ista: Yang P, Liu Y, Dong Q, Miao Y, Zhang J, Xu S, Zhao H, Niu Y, Zhang X, Xu Y, Guo Z, Xing L, Chong K. 2026. O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering. Nature Communications. 17, 999. mla: Yang, Pengfang, et al. “O-GlcNAc and Phosphorylation Modifications on HtL1/FBA10 Regulate Wheat Vernalization for Flowering.” Nature Communications, vol. 17, 999, Springer Nature, 2026, doi:10.1038/s41467-025-67734-0. short: P. Yang, Y. Liu, Q. Dong, Y. Miao, J. Zhang, S. Xu, H. Zhao, Y. Niu, X. Zhang, Y. Xu, Z. Guo, L. Xing, K. Chong, Nature Communications 17 (2026). date_created: 2026-02-08T23:02:48Z date_published: 2026-01-27T00:00:00Z date_updated: 2026-02-12T14:34:24Z day: '27' ddc: - '580' department: - _id: XiFe doi: 10.1038/s41467-025-67734-0 external_id: pmid: - '41455723' file: - access_level: open_access checksum: 9ae170ec70ba1ab56b6f1ffe67d1de7f content_type: application/pdf creator: dernst date_created: 2026-02-12T14:33:14Z date_updated: 2026-02-12T14:33:14Z file_id: '21223' file_name: 2026_NatureComm_Yang.pdf file_size: 4685882 relation: main_file success: 1 file_date_updated: 2026-02-12T14:33:14Z has_accepted_license: '1' intvolume: ' 17' language: - iso: eng month: '01' oa: 1 oa_version: Published Version pmid: 1 publication: Nature Communications publication_identifier: eissn: - 2041-1723 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: O-GlcNAc and phosphorylation modifications on HtL1/FBA10 regulate wheat vernalization for flowering tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 17 year: '2026' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '21159' abstract: - lang: eng text: "One of the foundational theorems of extremal graph theory is Dirac’s theorem, which\r\nsays that if an n-vertex graph G has minimum degree at least n/2, then G has a\r\nHamilton cycle, and therefore a perfect matching (if n is even). Later work by Sárközy,\r\nSelkow and Szemerédi showed that in fact Dirac graphs have many Hamilton cycles\r\nand perfect matchings, culminating in a result of Cuckler and Kahn that gives a precise\r\ndescription of the numbers of Hamilton cycles and perfect matchings in a Dirac graph\r\nG (in terms of an entropy-like parameter of G). In this paper we extend Cuckler\r\nand Kahn’s result to perfect matchings in hypergraphs. For positive integers d < k,\r\nand for n divisible by k, let md (k, n) be the minimum d-degree that ensures the\r\nexistence of a perfect matching in an n-vertex k-uniform hypergraph. In general, it is\r\nan open question to determine (even asymptotically) the values of md (k, n), but we are\r\nnonetheless able to prove an analogue of the Cuckler–Kahn theorem, showing that if\r\nan n-vertex k-uniform hypergraph G has minimum d-degree at least (1+γ )md (k, n)\r\n(for any constantγ > 0), then the number of perfect matchings in G is controlled by\r\nan entropy-like parameter of G. This strengthens cruder estimates arising from work\r\nof Kang–Kelly–Kühn–Osthus–Pfenninger and Pham–Sah–Sawhney–Simkin." acknowledgement: We would like to thank the referees for a number of helpful comments and suggestions, which have substantially improved the paper. Open access funding provided by Institute of Science and Technology (IST Austria). article_number: '5' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Matthew Alan full_name: Kwan, Matthew Alan id: 5fca0887-a1db-11eb-95d1-ca9d5e0453b3 last_name: Kwan orcid: 0000-0002-4003-7567 - first_name: Roodabeh full_name: Safavi Hemami, Roodabeh id: 72ed2640-8972-11ed-ae7b-f9c81ec75154 last_name: Safavi Hemami - first_name: Yiting full_name: Wang, Yiting id: 1917d194-076e-11ed-97cd-837255f88785 last_name: Wang orcid: 0000-0002-2856-767X citation: ama: Kwan MA, Safavi Hemami R, Wang Y. Counting perfect matchings in Dirac hypergraphs. Combinatorica. 2026;46. doi:10.1007/s00493-025-00194-8 apa: Kwan, M. A., Safavi Hemami, R., & Wang, Y. (2026). Counting perfect matchings in Dirac hypergraphs. Combinatorica. Springer Nature. https://doi.org/10.1007/s00493-025-00194-8 chicago: Kwan, Matthew Alan, Roodabeh Safavi Hemami, and Yiting Wang. “Counting Perfect Matchings in Dirac Hypergraphs.” Combinatorica. Springer Nature, 2026. https://doi.org/10.1007/s00493-025-00194-8. ieee: M. A. Kwan, R. Safavi Hemami, and Y. Wang, “Counting perfect matchings in Dirac hypergraphs,” Combinatorica, vol. 46. Springer Nature, 2026. ista: Kwan MA, Safavi Hemami R, Wang Y. 2026. Counting perfect matchings in Dirac hypergraphs. Combinatorica. 46, 5. mla: Kwan, Matthew Alan, et al. “Counting Perfect Matchings in Dirac Hypergraphs.” Combinatorica, vol. 46, 5, Springer Nature, 2026, doi:10.1007/s00493-025-00194-8. short: M.A. Kwan, R. Safavi Hemami, Y. Wang, Combinatorica 46 (2026). corr_author: '1' date_created: 2026-02-08T23:02:49Z date_published: 2026-02-01T00:00:00Z date_updated: 2026-02-16T09:55:17Z day: '01' ddc: - '510' department: - _id: MaKw - _id: MoHe doi: 10.1007/s00493-025-00194-8 external_id: arxiv: - '2408.09589' file: - access_level: open_access checksum: 47b0031d90b0e6b9a843f422a1486089 content_type: application/pdf creator: dernst date_created: 2026-02-16T09:52:38Z date_updated: 2026-02-16T09:52:38Z file_id: '21228' file_name: 2026_Combinatorica_Kwan.pdf file_size: 539646 relation: main_file success: 1 file_date_updated: 2026-02-16T09:52:38Z has_accepted_license: '1' intvolume: ' 46' language: - iso: eng month: '02' oa: 1 oa_version: Published Version publication: Combinatorica publication_identifier: eissn: - 1439-6912 issn: - 0209-9683 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Counting perfect matchings in Dirac hypergraphs tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 46 year: '2026' ... --- OA_place: publisher OA_type: diamond PlanS_conform: '1' _id: '21160' abstract: - lang: eng text: "Context. AM Canum Venaticorum (AM CVn) stars are ultra-compact binary systems composed of a white dwarf primary accreting from a hydrogen-deficient donor. They play a crucial role in astrophysics as potential progenitors of Type Ia supernovae and as laboratories for gravitational wave studies. However, their formation and evolutionary history remain incomplete. Three formation channels have been discussed in the literature: the white dwarf, He-star, and cataclysmic variable channels.\r\n\r\nAims. The chemical composition of the accretor atmosphere reflects the material transferred from the donor. In this work we took the first accurate measurements of the fundamental parameters of the accreting white dwarf in ZTF J225237.05−051917.4, including the abundances of key elements such as carbon, nitrogen, and silicon, by analysing ultraviolet spectra obtained with the Hubble Space Telescope (HST). These measurements provide new insight into the evolutionary history of the system and, together with existing optical observations, establish it as a benchmark to develop our pipeline, paving the way for its application to a larger sample of AM CVn systems.\r\n\r\nMethods. We determined the binary parameters through photometric analysis and constrained the atmospheric parameters of the white dwarf accretor, including its effective temperature, surface gravity, and chemical abundances, by fitting the HST ultraviolet spectrum with synthetic spectral models. We then inferred the system’s formation channel by comparing the results with theoretical evolutionary models.\r\n\r\nResults. According to our measurements, the accretor’s effective temperature (Teff) is 23 300 ± 600 K and the surface gravity (log g) is 8.4 ± 0.3, which imply an accretor mass (MWD) of 0.86 ± 0.16 M⊙. We find a high nitrogen-to-carbon abundance ratio by mass of > 153.\r\n\r\nConclusions. The accretor is significantly hotter than previous estimates based on simplified blackbody fits to the spectral energy distribution, underscoring the importance of detailed spectral modelling for accurately determining system parameters. Our results show that ultraviolet spectroscopy is well suited to constraining the formation channels of AM CVn systems. Of the three proposed formation channels, the He-star channel can be excluded given the high nitrogen-to-carbon ratio. Our results are consistent with both the white dwarf and cataclysmic variable channels." acknowledgement: "We thank Lars Bildsten for valuable insights and discussions. We acknowledge with thanks the variable star observations from the\r\nAAVSO International Database contributed by observers worldwide and used in this research. We thank the members of the Spanish Observers of Supernovae\r\n(ObSN) group for their valuable photometric contributions. This research was\r\nsupported by Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC 2121 “Quantum Universe”\r\n– 390833306. Co-funded by the European Union (ERC, CompactBINARIES,\r\n101078773). Views and opinions expressed are however those of the author(s)\r\nonly and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority\r\ncan be held responsible for them. DB acknowledges support from the São Paulo\r\nResearch Foundation (FAPESP), Brazil, Process Numbers #2024/03736-2 and\r\n#2025/00817-4. MRS is supported by Fondecyt (grant 1221059). MJG acknowledges support from the European Research Council through ERC Advanced\r\nGrant No. 101054731, from the National Aeronautics and Space Administration under grants 80NSSC24K0436, 80NSSC22K0479, and 80NSSC24K0380,\r\nand from the National Science Foundation under grant AST-2205736. PJG\r\nis supported by NRF SARChI grant 111692. PR-G acknowledges support by\r\nthe Agencia Estatal de Investigación del Ministerio de Ciencia e Innovación\r\n(MCIN/AEI) and the European Regional Development Fund (ERDF) under grant\r\nPID2021–124879NB–I00. DS is supported by the UK Science and Technology Facilities Council (STFC, grant numbers ST/T007184/1, ST/T003103/1,\r\nand ST/T000406/1). OT acknowledges Proyectos Internos USM 2025, PI-LII2025-03. GT was supported by grants IN109723 from the Programa de Apoyo a\r\nProyectos de Investigación e Innovación Tecnológica (PAPIIT). This project has\r\nreceived funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101020057)." article_number: A14 article_processing_charge: No article_type: original arxiv: 1 author: - first_name: W. full_name: Yu, W. last_name: Yu - first_name: A. F. full_name: Pala, A. F. last_name: Pala - first_name: T. full_name: Kupfer, T. last_name: Kupfer - first_name: B. T. full_name: Gänsicke, B. T. last_name: Gänsicke - first_name: D. full_name: Koester, D. last_name: Koester - first_name: D. full_name: Belloni, D. last_name: Belloni - first_name: T. L.S. full_name: Wong, T. L.S. last_name: Wong - first_name: M. R. full_name: Schreiber, M. R. last_name: Schreiber - first_name: Joannes C full_name: van Roestel, Joannes C id: 4d122fc8-6083-11f0-87a5-97d68b860333 last_name: van Roestel - first_name: A. J. full_name: Brown, A. J. last_name: Brown - first_name: E. O. full_name: Waagen, E. O. last_name: Waagen - first_name: J. L. full_name: González-Carballo, J. L. last_name: González-Carballo - first_name: S. full_name: Bednarz, S. last_name: Bednarz - first_name: K. full_name: Bernacki, K. last_name: Bernacki - first_name: D. full_name: De Martino, D. last_name: De Martino - first_name: E. full_name: Fernández Mañanes, E. last_name: Fernández Mañanes - first_name: R. full_name: González Farfán, R. last_name: González Farfán - first_name: M. J. full_name: Green, M. J. last_name: Green - first_name: P. J. full_name: Groot, P. J. last_name: Groot - first_name: F. J. full_name: Hambsch, F. J. last_name: Hambsch - first_name: C. full_name: Knigge, C. last_name: Knigge - first_name: J. L. full_name: Martin-Velasco, J. L. last_name: Martin-Velasco - first_name: M. full_name: Morales-Aimar, M. last_name: Morales-Aimar - first_name: G. full_name: Myers, G. last_name: Myers - first_name: R. full_name: Naves Nogues, R. last_name: Naves Nogues - first_name: R. full_name: Poggiani, R. last_name: Poggiani - first_name: A. full_name: Popowicz, A. last_name: Popowicz - first_name: G. full_name: Ramsay, G. last_name: Ramsay - first_name: E. full_name: Reina-Lorenz, E. last_name: Reina-Lorenz - first_name: P. full_name: Rodríguez-Gil, P. last_name: Rodríguez-Gil - first_name: J. L. full_name: Salto-González, J. L. last_name: Salto-González - first_name: E. M. full_name: Sion, E. M. last_name: Sion - first_name: D. full_name: Steeghs, D. last_name: Steeghs - first_name: P. full_name: Szkody, P. last_name: Szkody - first_name: O. full_name: Toloza, O. last_name: Toloza - first_name: G. full_name: Tovmassian, G. last_name: Tovmassian citation: ama: 'Yu W, Pala AF, Kupfer T, et al. The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and Astrophysics. 2026;706. doi:10.1051/0004-6361/202557568' apa: 'Yu, W., Pala, A. F., Kupfer, T., Gänsicke, B. T., Koester, D., Belloni, D., … Tovmassian, G. (2026). The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and Astrophysics. EDP Sciences. https://doi.org/10.1051/0004-6361/202557568' chicago: 'Yu, W., A. F. Pala, T. Kupfer, B. T. Gänsicke, D. Koester, D. Belloni, T. L.S. Wong, et al. “The Evolutionary History of Ultra-Compact Accreting Binaries: I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System ZTF J225237.05-051917.4 from HST Spectroscopy.” Astronomy and Astrophysics. EDP Sciences, 2026. https://doi.org/10.1051/0004-6361/202557568.' ieee: 'W. Yu et al., “The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy,” Astronomy and Astrophysics, vol. 706. EDP Sciences, 2026.' ista: 'Yu W, Pala AF, Kupfer T, Gänsicke BT, Koester D, Belloni D, Wong TLS, Schreiber MR, van Roestel JC, Brown AJ, Waagen EO, González-Carballo JL, Bednarz S, Bernacki K, De Martino D, Fernández Mañanes E, González Farfán R, Green MJ, Groot PJ, Hambsch FJ, Knigge C, Martin-Velasco JL, Morales-Aimar M, Myers G, Naves Nogues R, Poggiani R, Popowicz A, Ramsay G, Reina-Lorenz E, Rodríguez-Gil P, Salto-González JL, Sion EM, Steeghs D, Szkody P, Toloza O, Tovmassian G. 2026. The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy. Astronomy and Astrophysics. 706, A14.' mla: 'Yu, W., et al. “The Evolutionary History of Ultra-Compact Accreting Binaries: I. Chemical Abundances and the Formation Channel of the Eclipsing AM CVn System ZTF J225237.05-051917.4 from HST Spectroscopy.” Astronomy and Astrophysics, vol. 706, A14, EDP Sciences, 2026, doi:10.1051/0004-6361/202557568.' short: W. Yu, A.F. Pala, T. Kupfer, B.T. Gänsicke, D. Koester, D. Belloni, T.L.S. Wong, M.R. Schreiber, J.C. van Roestel, A.J. Brown, E.O. Waagen, J.L. González-Carballo, S. Bednarz, K. Bernacki, D. De Martino, E. Fernández Mañanes, R. González Farfán, M.J. Green, P.J. Groot, F.J. Hambsch, C. Knigge, J.L. Martin-Velasco, M. Morales-Aimar, G. Myers, R. Naves Nogues, R. Poggiani, A. Popowicz, G. Ramsay, E. Reina-Lorenz, P. Rodríguez-Gil, J.L. Salto-González, E.M. Sion, D. Steeghs, P. Szkody, O. Toloza, G. Tovmassian, Astronomy and Astrophysics 706 (2026). date_created: 2026-02-08T23:02:49Z date_published: 2026-02-01T00:00:00Z date_updated: 2026-02-16T09:36:24Z day: '01' ddc: - '520' department: - _id: IlCa doi: 10.1051/0004-6361/202557568 external_id: arxiv: - '2512.04147' file: - access_level: open_access checksum: 2faec710fd04f927aa43deb57e35c9b2 content_type: application/pdf creator: dernst date_created: 2026-02-16T09:33:56Z date_updated: 2026-02-16T09:33:56Z file_id: '21227' file_name: 2026_AstronomyAstrophysics_Yu.pdf file_size: 4020466 relation: main_file success: 1 file_date_updated: 2026-02-16T09:33:56Z has_accepted_license: '1' intvolume: ' 706' language: - iso: eng month: '02' oa: 1 oa_version: Published Version publication: Astronomy and Astrophysics publication_identifier: eissn: - 1432-0746 issn: - 0004-6361 publication_status: published publisher: EDP Sciences quality_controlled: '1' scopus_import: '1' status: public title: 'The evolutionary history of ultra-compact accreting binaries: I. Chemical abundances and the formation channel of the eclipsing AM CVn system ZTF J225237.05-051917.4 from HST spectroscopy' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 706 year: '2026' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '21161' abstract: - lang: eng text: In many species, sex-biased expression is widespread and thought to contribute to sexual dimorphism. While bulk RNA-sequencing has been instrumental in identifying strongly sex-biased genes, it lacks resolution to assess variation across cell-types and tissue compartments. Using single-nucleus expression data from the Fly Cell Atlas, we investigate sex differences in adult Drosophila melanogaster. We find that differences in cell-type composition between the sexes are not a major source of sex-bias, as for the vast majority of genes, the degree of sex-bias is similar regardless of whether sex differences in cell-type composition are controlled for or not. Our analysis confirms a deficit of X-linked male-biased genes in the body’s somatic tissues that is widespread across cell-types. We also find the excess of X-linked female-biased genes to be associated with nervous system cells in the head but with epithelial cells in the body’s somatic tissues, showing that single-nucleus data crucially resolves sex-bias at the cell-type level. We investigate dosage compensation (DC) across 15 tissues and 17 cell-types. We observe that it varies throughout the body. Surprisingly, we observe a lack of DC in a cluster of main cells within the male accessory glands. This result highlights the importance of understanding context-dependent DC. acknowledged_ssus: - _id: ScienComp - _id: Bio acknowledgement: This work was partly funded by an Austrian Science Foundation FWF ESPRIT fellowship (10.55776/ESP6331524) to C.B. We would like to thank the Vicoso group for their invaluable input and discussions throughout this work. We thank Filip Ruzicka for his insightful comments on the manuscript. All computational resources were provided by the Scientific Computing Unit at ISTA. This research was also supported through resources provided by the Imaging & Optics Facility (IOF) at ISTA. article_number: '20252471' article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Carolina full_name: De Castro Barbosa Rodrigues Barata, Carolina id: 20565186-803f-11ed-ab7e-96a4ff7694ef last_name: De Castro Barbosa Rodrigues Barata orcid: 0000-0003-1945-2245 - first_name: Beatriz full_name: Vicoso, Beatriz id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87 last_name: Vicoso orcid: 0000-0002-4579-8306 citation: ama: de Castro Barbosa Rodrigues Barata C, Vicoso B. Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings of the Royal Society B Biological Sciences. 2026;293(2063). doi:10.1098/rspb.2025.2471 apa: de Castro Barbosa Rodrigues Barata, C., & Vicoso, B. (2026). Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings of the Royal Society B Biological Sciences. Royal Society of London. https://doi.org/10.1098/rspb.2025.2471 chicago: Castro Barbosa Rodrigues Barata, Carolina de, and Beatriz Vicoso. “Single-Nucleus Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.” Proceedings of the Royal Society B Biological Sciences. Royal Society of London, 2026. https://doi.org/10.1098/rspb.2025.2471. ieee: C. de Castro Barbosa Rodrigues Barata and B. Vicoso, “Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster,” Proceedings of the Royal Society B Biological Sciences, vol. 293, no. 2063. Royal Society of London, 2026. ista: de Castro Barbosa Rodrigues Barata C, Vicoso B. 2026. Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster. Proceedings of the Royal Society B Biological Sciences. 293(2063), 20252471. mla: de Castro Barbosa Rodrigues Barata, Carolina, and Beatriz Vicoso. “Single-Nucleus Resolution of Sex-Biased Expression and Dosage Compensation in Drosophila Melanogaster.” Proceedings of the Royal Society B Biological Sciences, vol. 293, no. 2063, 20252471, Royal Society of London, 2026, doi:10.1098/rspb.2025.2471. short: C. de Castro Barbosa Rodrigues Barata, B. Vicoso, Proceedings of the Royal Society B Biological Sciences 293 (2026). corr_author: '1' date_created: 2026-02-08T23:02:49Z date_published: 2026-01-28T00:00:00Z date_updated: 2026-02-16T09:27:33Z day: '28' ddc: - '570' department: - _id: BeVi doi: 10.1098/rspb.2025.2471 external_id: pmid: - '41592777' file: - access_level: open_access checksum: d76afebca0a6f112df0146ae2d929f36 content_type: application/pdf creator: dernst date_created: 2026-02-16T09:26:02Z date_updated: 2026-02-16T09:26:02Z file_id: '21226' file_name: 2026_RoyalSocPubProceedingsB_Barata.pdf file_size: 2230841 relation: main_file success: 1 file_date_updated: 2026-02-16T09:26:02Z has_accepted_license: '1' intvolume: ' 293' issue: '2063' language: - iso: eng month: '01' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 90ef7108-16d5-11f0-9cad-e6e116913473 grant_number: ESP 6331524 name: Does genetic drift set a limit on the adaptive evolution of sex-biased expression? publication: Proceedings of the Royal Society B Biological Sciences publication_identifier: eissn: - 1471-2954 publication_status: published publisher: Royal Society of London quality_controlled: '1' scopus_import: '1' status: public title: Single-nucleus resolution of sex-biased expression and dosage compensation in Drosophila melanogaster tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 293 year: '2026' ... --- _id: '21164' abstract: - lang: eng text: 'Global emission inventories often fail to capture the complexities of vehicular pollution in regions with unique fuel mixes, such as Brazil’s extensive biofuel use, leading to significant uncertainties in atmospheric modeling. This study presents a century-long (1960–2100) bottom-up vehicular emission inventory for Brazil, leveraging locally derived emission factors. Our estimates reveal substantial discrepancies in magnitude, timing, and speciation of non-CO2 pollutants (CO, NMHC, PM2.5) compared to leading global inventories (EDGAR, CEDS, CAMS), highlighting critical inaccuracies in widely used data sets. More critically, future projections under Shared Socioeconomic Pathways (SSPs) uncover a novel positive feedback mechanism: rising temperatures significantly enhance vehicular evaporative nonmethane hydrocarbon (NMHC) emissions. This temperature-dependent increase and subsequent NMHC oxidation to CO2 suggest an overlooked pathway that could amplify climate warming and air pollution globally, particularly after a breakpoint around 2050 (p < 0.05). While historical emissions peaked in the 1990s–2000s, nonexhaust PM becomes increasingly important. Air quality simulations using our inventory in the MUSICA model show good regional PM2.5 agreement but highlight challenges in resolving local primary pollutant peaks. This comprehensive inventory provides crucial data for Brazil and uncovers globally relevant climate–chemistry interactions, urging a re-evaluation of regional specificities in global emission assessments.' acknowledgement: Part of this material is based upon work supported by the NSF National Center for Atmospheric Research, which is a major facility sponsored by the National Science Foundation under Cooperative Agreement No. 1852977. Casallas was supported by the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 101034413. E. D. Freitas thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 313210/2022–5). Silva gratefully acknowledges the financial support from the National Council for Scientific and Technological Development (CNPq), process number 140512/2021–7. P. Lichtig was supported by base funding from the National Commission for Atomic Energy (CNEA, Arg.) and by NSF NCAR. R.Y. Ynoue thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 406728/2022–4). M. A. Franco thanks the support provided by the National Council for Scientific and Technological Development (CNPq, Process number 407752/2023–4). G. M. Pereira thanks the support by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP; Process numbers 2018/07848–9, 2016/18438–0, and 2019/01316–80) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES; Process number 88887.103225/2025–00). M.F. Andrade thanks the support by FAPESP (Process number 2016/18438–0) and CNPQ (Klimapolis INCT). article_number: 5c08400 article_processing_charge: No article_type: original author: - first_name: Sergio full_name: Ibarra-Espinosa, Sergio last_name: Ibarra-Espinosa - first_name: Edmilson full_name: Dias de Freitas, Edmilson last_name: Dias de Freitas - first_name: Benjamin full_name: Gaubert, Benjamin last_name: Gaubert - first_name: Pablo full_name: Lichtig, Pablo last_name: Lichtig - first_name: Karl full_name: Ropkins, Karl last_name: Ropkins - first_name: Iara full_name: da Silva, Iara last_name: da Silva - first_name: Guilherme full_name: Martins Pereira, Guilherme last_name: Martins Pereira - first_name: Daniel full_name: Schuch, Daniel last_name: Schuch - first_name: Janaina full_name: Nascimento, Janaina last_name: Nascimento - first_name: Leonardo full_name: Hoinaski, Leonardo last_name: Hoinaski - first_name: Leila Droprinchinski full_name: Martins, Leila Droprinchinski last_name: Martins - first_name: Mario full_name: Gavidia-Calderón, Mario last_name: Gavidia-Calderón - first_name: Angel full_name: Vara-Vela, Angel last_name: Vara-Vela - first_name: Taciana full_name: Toledo de Almeida Albuquerque, Taciana last_name: Toledo de Almeida Albuquerque - first_name: Rita Yuri full_name: Ynoue, Rita Yuri last_name: Ynoue - first_name: Sebastian full_name: Diez, Sebastian last_name: Diez - first_name: Zamir full_name: Mera, Zamir last_name: Mera - first_name: Alejandro full_name: Casallas Garcia, Alejandro id: 92081129-2d75-11ef-a48d-b04dd7a2385a last_name: Casallas Garcia orcid: 0000-0002-1988-5035 - first_name: Fidel full_name: Vallejo, Fidel last_name: Vallejo - first_name: Valeria full_name: Diaz, Valeria last_name: Diaz - first_name: Rizzieri full_name: Pedruzzi, Rizzieri last_name: Pedruzzi - first_name: Rosana full_name: Abrutzky, Rosana last_name: Abrutzky - first_name: Marco A. full_name: Franco, Marco A. last_name: Franco - first_name: Nicolas full_name: Huneeus, Nicolas last_name: Huneeus - first_name: Hector full_name: Jorquera, Hector last_name: Jorquera - first_name: Luis Carlos full_name: Belalcázar-Cerón, Luis Carlos last_name: Belalcázar-Cerón - first_name: Néstor Y. full_name: Rojas, Néstor Y. last_name: Rojas - first_name: Maria full_name: de Fatima Andrade, Maria last_name: de Fatima Andrade - first_name: Louisa full_name: Emmons, Louisa last_name: Emmons - first_name: Guy full_name: Brasseur, Guy last_name: Brasseur citation: ama: 'Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, et al. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology. 2026. doi:10.1021/acs.est.5c08400' apa: 'Ibarra-Espinosa, S., Dias de Freitas, E., Gaubert, B., Lichtig, P., Ropkins, K., da Silva, I., … Brasseur, G. (2026). A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology. American Chemical Society. https://doi.org/10.1021/acs.est.5c08400' chicago: 'Ibarra-Espinosa, Sergio, Edmilson Dias de Freitas, Benjamin Gaubert, Pablo Lichtig, Karl Ropkins, Iara da Silva, Guilherme Martins Pereira, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” Environmental Science &amp; Technology. American Chemical Society, 2026. https://doi.org/10.1021/acs.est.5c08400.' ieee: 'S. Ibarra-Espinosa et al., “A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality,” Environmental Science &amp; Technology. American Chemical Society, 2026.' ista: 'Ibarra-Espinosa S, Dias de Freitas E, Gaubert B, Lichtig P, Ropkins K, da Silva I, Martins Pereira G, Schuch D, Nascimento J, Hoinaski L, Martins LD, Gavidia-Calderón M, Vara-Vela A, Toledo de Almeida Albuquerque T, Ynoue RY, Diez S, Mera Z, Casallas Garcia A, Vallejo F, Diaz V, Pedruzzi R, Abrutzky R, Franco MA, Huneeus N, Jorquera H, Belalcázar-Cerón LC, Rojas NY, de Fatima Andrade M, Emmons L, Brasseur G. 2026. A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality. Environmental Science &amp; Technology., 5c08400.' mla: 'Ibarra-Espinosa, Sergio, et al. “A Century of Vehicular Emissions in Brazil: Unveiling the Impacts of Unique Fuel Mix on Air Quality.” Environmental Science &amp; Technology, 5c08400, American Chemical Society, 2026, doi:10.1021/acs.est.5c08400.' short: S. Ibarra-Espinosa, E. Dias de Freitas, B. Gaubert, P. Lichtig, K. Ropkins, I. da Silva, G. Martins Pereira, D. Schuch, J. Nascimento, L. Hoinaski, L.D. Martins, M. Gavidia-Calderón, A. Vara-Vela, T. Toledo de Almeida Albuquerque, R.Y. Ynoue, S. Diez, Z. Mera, A. Casallas Garcia, F. Vallejo, V. Diaz, R. Pedruzzi, R. Abrutzky, M.A. Franco, N. Huneeus, H. Jorquera, L.C. Belalcázar-Cerón, N.Y. Rojas, M. de Fatima Andrade, L. Emmons, G. Brasseur, Environmental Science &amp; Technology (2026). date_created: 2026-02-09T06:54:10Z date_published: 2026-02-04T00:00:00Z date_updated: 2026-02-16T10:33:07Z day: '04' ddc: - '550' department: - _id: CaMu doi: 10.1021/acs.est.5c08400 ec_funded: 1 external_id: pmid: - '41636708' has_accepted_license: '1' language: - iso: eng month: '02' oa_version: None pmid: 1 project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: Environmental Science & Technology publication_identifier: eissn: - 1520-5851 issn: - 0013-936X publication_status: epub_ahead publisher: American Chemical Society quality_controlled: '1' scopus_import: '1' status: public title: 'A century of vehicular emissions in Brazil: Unveiling the impacts of unique fuel mix on air quality' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ... --- OA_place: repository OA_type: free access _id: '21174' abstract: - lang: eng text: UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby the zero-resistance state reappears above 40 tesla after being suppressed with a field of around 10 tesla. One potential pairing mechanism, invoked in the related re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of a ferromagnetic order parameter. However, the requisite ferromagnetic order - present in both UCoGe and URhGe - is absent in UTe2, and magnetization measurements show no sign of strong fluctuations. Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle planes. This quantity is sensitive to the magnetic susceptibility in a direction transverse to the applied magnetic field - a quantity that is not accessed in conventional magnetization measurements. We observe a very large decrease in the magnetotropic susceptibility over a broad range of field orientations, indicating a large increase in the transverse magnetic susceptibility. The three superconducting phases of UTe2, including the high-field re-entrant phase, surround this region of enhanced susceptibility in the field-angle phase diagram. The strongest transverse susceptibility is found near the critical end point of the high-field metamagnetic transition, suggesting that quantum critical fluctuations of a field-induced magnetic order parameter may be responsible for the large transverse susceptibility, and may provide a pairing mechanism for field-induced superconductivity in UTe2. acknowledged_ssus: - _id: NanoFab acknowledgement: Thanks to Salvatore Bagiante, Evgeniia Volobueva, Lubuna Shafeek, Ali Bangura and Zoltan Kollo. article_processing_charge: Yes author: - first_name: Kimberly A full_name: Modic, Kimberly A id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425 last_name: Modic orcid: 0000-0001-9760-3147 citation: ama: Modic KA. Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” 2026. doi:10.15479/AT-ISTA-21174 apa: Modic, K. A. (2026). Research data for “Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21174 chicago: Modic, Kimberly A. “Research Data for ‘Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21174. ieee: K. A. Modic, “Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2.’” Institute of Science and Technology Austria, 2026. ista: Modic KA. 2026. Research data for ‘Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21174. mla: Modic, Kimberly A. Research Data for “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity in UTe2.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21174. short: K.A. Modic, (2026). contributor: - contributor_type: project_member first_name: Valeska id: 467ed36b-dc96-11ea-b7c8-b043a380b282 last_name: Zambra orcid: 0000-0002-8806-5719 corr_author: '1' date_created: 2026-02-09T12:04:20Z date_published: 2026-02-19T00:00:00Z date_updated: 2026-02-19T10:13:30Z day: '19' ddc: - '530' department: - _id: KiMo doi: 10.15479/AT-ISTA-21174 file: - access_level: open_access checksum: 53157d908fba663275c2b8dc6ee84fdb content_type: text/plain creator: kmodic date_created: 2026-02-19T07:38:15Z date_updated: 2026-02-19T07:38:15Z file_id: '21332' file_name: README.txt file_size: 1347 relation: main_file success: 1 - access_level: open_access checksum: b2c8ca5620ee9c181a42082068d3d73c content_type: application/zip creator: kmodic date_created: 2026-02-19T07:39:03Z date_updated: 2026-02-19T07:39:03Z file_id: '21333' file_name: processed_data_bc_plane_Fig2d.zip file_size: 534853 relation: main_file success: 1 - access_level: open_access checksum: 976bf113da4b1133313f0b292e71289f content_type: application/zip creator: kmodic date_created: 2026-02-19T07:39:07Z date_updated: 2026-02-19T07:39:07Z file_id: '21334' file_name: processed_data_ac_plane_Fig2c.zip file_size: 427144 relation: main_file success: 1 file_date_updated: 2026-02-19T07:39:07Z has_accepted_license: '1' keyword: - transverse magnetic susceptibility - magnetotropic - superconductivity - magnetic fluctuations month: '02' oa: 1 oa_version: Published Version project: - _id: bd968c70-d553-11ed-ba76-cde40b0aba64 grant_number: '101078696' name: Gaining leverage with spin liquids and superconductors publisher: Institute of Science and Technology Austria related_material: link: - relation: preprint url: https://arxiv.org/pdf/2506.08984 status: public title: Research data for "Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity in UTe2" tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: research_data user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d year: '2026' ... --- OA_place: repository OA_type: green _id: '21212' abstract: - lang: eng text: "Malignant glioma is incurable. Using a mouse genetic mosaic system to generate sporadic Trp53,Nf1-null OPCs, we previously identified oligodendrocyte precursor cell (OPC) as a cell-of-origin of glioma. Here, we report that pre-malignant Trp53,Nf1-null OPCs outcompete wildtype counterparts during their expansion. Blocking competition by mutating/strengthening wildtype OPCs impeded both pre-malignant progression and malignant expansion of glioma.\r\n\r\n“In-tissue” phosphoproteomic profiling revealed an enrichment of phosphopeptides related to RNA splicing and protein translation at the peak of cell competition, suggesting that competitiveness may stem from unique protein species. Among candidates was mTORC1, whose pharmacological inhibition or genetic disruption resulted in a loss of competitiveness in our mouse model. Finally, analysis of patient biopsies and interrogating the role of individual gliomagenic mutations in OPC competition supported its relevance in human gliomas. Together, these findings identified the driving role of competitive interactions among OPCs in gliomagenesis, and suggest unconventional therapeutic strategies to target this process." acknowledgement: "We thank Dr. Wenjie Liu for providing critical feedback on the manuscript. We also thank Dr.\r\nPat Pramoonjago at the Biorepository and Tissue Research Facility, and Hope Davis at the\r\nvivarium for their assistance on the project. These Core Facilities are supported by UVA Cancer\r\nCenter grant #P30-CA044579. We are grateful to Dr. Jonathan A. Epstein for providing the\r\nNf1GRD/+ mouse strain (https://pubmed.ncbi.nlm.nih.gov/26460546/). This work was partly\r\nsupported by the National Institute of Neurological Diseases and Stroke R21 NS125479-01A1\r\n(H.Z.), American Cancer Society Institutional Research Grant to the University of Virginia\r\n(Y.J.), the National Natural Science Foundation of China #82072787 (M.Y.), the National\r\nCancer Institute U54 CA238114 (F.W.), U01 CA284193 (K.M.N.), and U54 CA274499 (K.A.J.,\r\nM.F-S.), the National institute of General Medical Sciences R35 GM133404 (M.F-S.), the Dr.\r\nMiriam and Sheldon G. Adelson Medical Research Foundation (H.I.K., S.A.G.), the National\r\nCenter for Advancing Translational Sciences KL2TR001882 (K.S.P.), Tower Cancer Career Development Grant (K.S.P.), McKnight Neurobiology of Brain Disorders Grant (K.S.P.). The\r\ncontent is solely the responsibility of the authors and does not necessarily represent the official\r\nviews of the National Institutes of Health. Illustrations in this manuscript were created with\r\nBioRender (BioRender.com)." article_processing_charge: No author: - first_name: Ying full_name: Jiang, Ying last_name: Jiang - first_name: Ryuhjin full_name: Ahn, Ryuhjin last_name: Ahn - first_name: Arthur full_name: Huang, Arthur last_name: Huang - first_name: Phillippe P. full_name: Gonzalez, Phillippe P. last_name: Gonzalez - first_name: Jungeun full_name: Kim, Jungeun last_name: Kim - first_name: Guoxin full_name: Zhang, Guoxin last_name: Zhang - first_name: Zihao full_name: Liu, Zihao last_name: Liu - first_name: Zhenqiang full_name: He, Zhenqiang last_name: He - first_name: Lindsey full_name: Dudley, Lindsey last_name: Dudley - first_name: Kunal S. full_name: Patel, Kunal S. last_name: Patel - first_name: Godfrey A. full_name: Dzhivhuho, Godfrey A. last_name: Dzhivhuho - first_name: Sam full_name: Crowl, Sam last_name: Crowl - first_name: Piotr full_name: Przanowski, Piotr last_name: Przanowski - first_name: Luisa Quesada full_name: Camacho, Luisa Quesada last_name: Camacho - first_name: Sijie full_name: Hao, Sijie last_name: Hao - first_name: Jianhao full_name: Zeng, Jianhao last_name: Zeng - first_name: Simon full_name: Hippenmeyer, Simon id: 37B36620-F248-11E8-B48F-1D18A9856A87 last_name: Hippenmeyer orcid: 0000-0003-2279-1061 - first_name: Mohammad full_name: Fallahi-Sichani, Mohammad last_name: Fallahi-Sichani - first_name: Kevin A. full_name: Janes, Kevin A. last_name: Janes - first_name: Kristen M. full_name: Naegle, Kristen M. last_name: Naegle - first_name: Marie-Louise full_name: Hammarskjold, Marie-Louise last_name: Hammarskjold - first_name: Steven A. full_name: Goldman, Steven A. last_name: Goldman - first_name: Harley I. full_name: Kornblum, Harley I. last_name: Kornblum - first_name: Maojin full_name: Yao, Maojin last_name: Yao - first_name: Forest full_name: White, Forest last_name: White - first_name: Hui full_name: Zong, Hui last_name: Zong citation: ama: Jiang Y, Ahn R, Huang A, et al. Critical role of cell competition in gliomagenesis. bioRxiv. 2026. doi:10.64898/2026.01.15.699808 apa: Jiang, Y., Ahn, R., Huang, A., Gonzalez, P. P., Kim, J., Zhang, G., … Zong, H. (2026). Critical role of cell competition in gliomagenesis. bioRxiv. https://doi.org/10.64898/2026.01.15.699808 chicago: Jiang, Ying, Ryuhjin Ahn, Arthur Huang, Phillippe P. Gonzalez, Jungeun Kim, Guoxin Zhang, Zihao Liu, et al. “Critical Role of Cell Competition in Gliomagenesis.” BioRxiv, 2026. https://doi.org/10.64898/2026.01.15.699808. ieee: Y. Jiang et al., “Critical role of cell competition in gliomagenesis,” bioRxiv. 2026. ista: Jiang Y, Ahn R, Huang A, Gonzalez PP, Kim J, Zhang G, Liu Z, He Z, Dudley L, Patel KS, Dzhivhuho GA, Crowl S, Przanowski P, Camacho LQ, Hao S, Zeng J, Hippenmeyer S, Fallahi-Sichani M, Janes KA, Naegle KM, Hammarskjold M-L, Goldman SA, Kornblum HI, Yao M, White F, Zong H. 2026. Critical role of cell competition in gliomagenesis. bioRxiv, 10.64898/2026.01.15.699808. mla: Jiang, Ying, et al. “Critical Role of Cell Competition in Gliomagenesis.” BioRxiv, 2026, doi:10.64898/2026.01.15.699808. short: Y. Jiang, R. Ahn, A. Huang, P.P. Gonzalez, J. Kim, G. Zhang, Z. Liu, Z. He, L. Dudley, K.S. Patel, G.A. Dzhivhuho, S. Crowl, P. Przanowski, L.Q. Camacho, S. Hao, J. Zeng, S. Hippenmeyer, M. Fallahi-Sichani, K.A. Janes, K.M. Naegle, M.-L. Hammarskjold, S.A. Goldman, H.I. Kornblum, M. Yao, F. White, H. Zong, BioRxiv (2026). date_created: 2026-02-10T12:55:55Z date_published: 2026-01-16T00:00:00Z date_updated: 2026-02-16T10:12:42Z day: '16' ddc: - '570' department: - _id: SiHi doi: 10.64898/2026.01.15.699808 has_accepted_license: '1' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ main_file_link: - open_access: '1' url: https://doi.org/10.64898/2026.01.15.699808 month: '01' oa: 1 oa_version: Preprint publication: bioRxiv publication_status: published status: public title: Critical role of cell competition in gliomagenesis tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ... --- OA_place: publisher OA_type: hybrid _id: '21217' abstract: - lang: eng text: This study investigates the mechanisms driving clustered convection and the breakdown of the Intertropical Convergence Zone (ITCZ) over the Western Pacific Warm Pool using high‐resolution cloud‐resolving simulations and machine‐learning sensitivity experiments. Results show that ITCZ breakdown episodes, marked by spatially homogeneous convection and weakened meridional moisture gradients, are triggered primarily by anomalous moisture advection linked to the equatorial Rossby‐wave activity. While large‐scale moisture advection regulates the background convective state strongly, it is the surface and low‐level meridional winds that dominate transitions between clustered and random convection. Simulations demonstrate that moisture alone can sustain convective clustering, but breakdown episodes are more persistent and widespread when coupled with southerly meridional advection. These findings confirm that wave‐driven advection acts as a regulatory mechanism, periodically disrupting convective clustering and reshaping the meridional moisture gradient. This modulation of organization by wave‐induced breakdown events is critical for understanding tropical convection variability and its implications for the climate system. acknowledgement: This article is based on chapter 5 of the PhD thesis of A. Casallas. The authors thank Graziano Giuliani for discussions on the boundary-condition experiments. A. Casallas was supported by a PhD fellowship awarded by the Abdus Salam International Centre for Theoretical Physics. A. Casallas also acknowledges support by the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 101034413. C. Muller acknowledges funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). The authors gratefully acknowledge Daniel Hernández-Deckers, Lokahith Agasthya, Chris Holloway, and Paolina Cerlini for their valuable feedback and insightful discussions. They are especially thankful to Bety Pechacova for suggesting the use of SHAP to complement their analysis. They also thank the two anonymous reviewers for their constructive comments, which improved the quality and clarity of the article significantly. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ. article_number: e70131 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Alejandro full_name: Casallas Garcia, Alejandro id: 92081129-2d75-11ef-a48d-b04dd7a2385a last_name: Casallas Garcia orcid: 0000-0002-1988-5035 - first_name: Adrian full_name: Mark Tompkins, Adrian last_name: Mark Tompkins - first_name: Caroline J full_name: Muller, Caroline J id: f978ccb0-3f7f-11eb-b193-b0e2bd13182b last_name: Muller orcid: 0000-0001-5836-5350 citation: ama: Casallas Garcia A, Mark Tompkins A, Muller CJ. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society. 2026. doi:10.1002/qj.70131 apa: Casallas Garcia, A., Mark Tompkins, A., & Muller, C. J. (2026). Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society. Wiley. https://doi.org/10.1002/qj.70131 chicago: Casallas Garcia, Alejandro, Adrian Mark Tompkins, and Caroline J Muller. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” Quarterly Journal of the Royal Meteorological Society. Wiley, 2026. https://doi.org/10.1002/qj.70131. ieee: A. Casallas Garcia, A. Mark Tompkins, and C. J. Muller, “Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events,” Quarterly Journal of the Royal Meteorological Society. Wiley, 2026. ista: Casallas Garcia A, Mark Tompkins A, Muller CJ. 2026. Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events. Quarterly Journal of the Royal Meteorological Society., e70131. mla: Casallas Garcia, Alejandro, et al. “Moisture and Wind Effects of Rossby Waves on Western Pacific Intertropical Convergence Zone Breakdown Events.” Quarterly Journal of the Royal Meteorological Society, e70131, Wiley, 2026, doi:10.1002/qj.70131. short: A. Casallas Garcia, A. Mark Tompkins, C.J. Muller, Quarterly Journal of the Royal Meteorological Society (2026). corr_author: '1' date_created: 2026-02-12T10:13:02Z date_published: 2026-02-12T00:00:00Z date_updated: 2026-02-16T10:19:52Z day: '12' ddc: - '550' department: - _id: CaMu doi: 10.1002/qj.70131 ec_funded: 1 has_accepted_license: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1002/qj.70131 month: '02' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' - _id: 629205d8-2b32-11ec-9570-e1356ff73576 call_identifier: H2020 grant_number: '805041' name: Organization of CLoUdS, and implications of Tropical cyclones and for the Energetics of the tropics, in current and waRming climate publication: Quarterly Journal of the Royal Meteorological Society publication_identifier: eissn: - 1477-870X issn: - 0035-9009 publication_status: epub_ahead publisher: Wiley quality_controlled: '1' scopus_import: '1' status: public title: Moisture and wind effects of Rossby waves on Western Pacific Intertropical Convergence Zone breakdown events tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ... --- OA_place: repository OA_type: green _id: '21230' abstract: - lang: eng text: Asteroseismology is the study of the interior physics and structure of stars using their pulsations. It is applicable to stars across the Hertzsprung–Russell (HR) diagram and a powerful technique not only to measure masses, radii, and ages but also directly constrain interior rotation, chemical mixing, and magnetism. This is because a star's self-excited pulsation modes are sensitive to its structure. Asteroseismology generally requires long-duration and high-precision time-series data. The method of forward asteroseismic modeling, which is the statistical comparison of observed pulsation mode frequencies to theoretically predicted pulsation frequencies calculated from a grid of models, provides precise constraints for calibrating various transport phenomena. In this introduction to asteroseismology, we provide an overview of its principles, and the typical data sets and methodologies used to constrain stellar interiors. Finally, we present key highlights of asteroseismic results from across the HR diagram, and conclude with ongoing challenges and future prospects for this ever-expanding field within stellar astrophysics. article_processing_charge: No arxiv: 1 author: - first_name: Dominic M. full_name: Bowman, Dominic M. last_name: Bowman - first_name: Lisa Annabelle full_name: Bugnet, Lisa Annabelle id: d9edb345-f866-11ec-9b37-d119b5234501 last_name: Bugnet orcid: 0000-0003-0142-4000 citation: ama: 'Bowman DM, Bugnet LA. Asteroseismology. In: Mandel I, ed. Encyclopedia of Astrophysics. Vol 2. Elsevier; 2026:133-153. doi:10.1016/b978-0-443-21439-4.00036-5' apa: Bowman, D. M., & Bugnet, L. A. (2026). Asteroseismology. In I. Mandel (Ed.), Encyclopedia of Astrophysics (Vol. 2, pp. 133–153). Elsevier. https://doi.org/10.1016/b978-0-443-21439-4.00036-5 chicago: Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” In Encyclopedia of Astrophysics, edited by Ilya Mandel, 2:133–53. Elsevier, 2026. https://doi.org/10.1016/b978-0-443-21439-4.00036-5. ieee: D. M. Bowman and L. A. Bugnet, “Asteroseismology,” in Encyclopedia of Astrophysics, vol. 2, I. Mandel, Ed. Elsevier, 2026, pp. 133–153. ista: 'Bowman DM, Bugnet LA. 2026.Asteroseismology. In: Encyclopedia of Astrophysics. vol. 2, 133–153.' mla: Bowman, Dominic M., and Lisa Annabelle Bugnet. “Asteroseismology.” Encyclopedia of Astrophysics, edited by Ilya Mandel, vol. 2, Elsevier, 2026, pp. 133–53, doi:10.1016/b978-0-443-21439-4.00036-5. short: D.M. Bowman, L.A. Bugnet, in:, I. Mandel (Ed.), Encyclopedia of Astrophysics, Elsevier, 2026, pp. 133–153. date_created: 2026-02-16T10:43:01Z date_published: 2026-01-01T00:00:00Z date_updated: 2026-02-17T11:05:20Z day: '01' department: - _id: LiBu doi: 10.1016/b978-0-443-21439-4.00036-5 editor: - first_name: Ilya full_name: Mandel, Ilya last_name: Mandel external_id: arxiv: - '2410.01715' intvolume: ' 2' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2410.01715 month: '01' oa: 1 oa_version: Preprint page: 133-153 publication: Encyclopedia of Astrophysics publication_identifier: isbn: - '9780443214400' publication_status: published publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: Asteroseismology type: book_chapter user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 2 year: '2026' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '21232' abstract: - lang: eng text: "Abstract\r\n In this paper, we consider a simple class of stratified spaces – 2-complexes. We present an algorithm that learns the abstract structure of an embedded 2-complex from a point cloud sampled from it. We use tools and inspiration from computational geometry, algebraic topology, and topological data analysis and prove the correctness of the identified abstract structure under assumptions on the embedding." acknowledgement: The author would like to thank Kate Turner, Chris Williams, Jonathan Spreer, Stephan Tillmann, Vanessa Robins, Vigleik Angeltveit, Martin Helmer, and James Morgan for very helpful discussions; and thanks Sara Kališnik Hintz and Paul Bendich for comments on an earlier version. Additonally, the author would like to thank both reviewers for their very insightful and helpful comments, without which the paper would be infinitely less coherent than it currently is. Open access funding provided by Institute of Science and Technology (IST Austria). The work in this paper was supported by an Australian Federal Government Grant, 2019-2022, Stratified Space Learning. article_number: '17' article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Yossi full_name: Bleile, Yossi id: 920a7385-7995-11ef-9bfd-8c434cd8f3c2 last_name: Bleile orcid: 0000-0002-4861-9174 citation: ama: 'Bleile Y. Towards stratified space learning: 2-complexes. La Matematica. 2026;5. doi:10.1007/s44007-025-00183-9' apa: 'Bleile, Y. (2026). Towards stratified space learning: 2-complexes. La Matematica. Springer Nature. https://doi.org/10.1007/s44007-025-00183-9' chicago: 'Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” La Matematica. Springer Nature, 2026. https://doi.org/10.1007/s44007-025-00183-9.' ieee: 'Y. Bleile, “Towards stratified space learning: 2-complexes,” La Matematica, vol. 5. Springer Nature, 2026.' ista: 'Bleile Y. 2026. Towards stratified space learning: 2-complexes. La Matematica. 5, 17.' mla: 'Bleile, Yossi. “Towards Stratified Space Learning: 2-Complexes.” La Matematica, vol. 5, 17, Springer Nature, 2026, doi:10.1007/s44007-025-00183-9.' short: Y. Bleile, La Matematica 5 (2026). corr_author: '1' date_created: 2026-02-16T10:44:44Z date_published: 2026-02-08T00:00:00Z date_updated: 2026-02-23T10:20:10Z day: '08' ddc: - '510' department: - _id: HeEd doi: 10.1007/s44007-025-00183-9 external_id: arxiv: - '2305.02724' file: - access_level: open_access checksum: 6cae2efb47b025af22a8539c606a4e09 content_type: application/pdf creator: dernst date_created: 2026-02-23T10:18:52Z date_updated: 2026-02-23T10:18:52Z file_id: '21347' file_name: 2026_LaMatematica_Bleile.pdf file_size: 15051582 relation: main_file success: 1 file_date_updated: 2026-02-23T10:18:52Z has_accepted_license: '1' intvolume: ' 5' language: - iso: eng month: '02' oa: 1 oa_version: Published Version publication: La Matematica publication_identifier: issn: - 2730-9657 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: 'Towards stratified space learning: 2-complexes' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 5 year: '2026' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '21233' abstract: - lang: eng text: Potential self-perpetuating dieback of the Amazon rain forest has been a topic of concern. The concern is that initial deforestation could critically impair the forest’s water recycling capacities, further harming the remaining forest through reduced annual precipitation. Many studies have focused on annual mean precipitation changes, due to its widespread perception as a central control on the Amazon rain forest’s stability. However, the impact of deforestation goes beyond changes in the annual mean precipitation. Yet, global coarse-resolution climate models are not well suited to investigate changes in short-duration and localized events due to their coarse resolution. Here, we circumvent these issues by analyzing a full-deforestation scenario simulated by a global storm-resolving model. We focus on changes in the tail of the hourly distribution of precipitation, temperature, and wind. Hourly precipitation becomes more extreme in the absence of the forest than in an intact forest, with an increased occurrence of both no rain and intense rainfall. These changes are driven by enhanced moisture convergence that strengthens vertical velocity. On average, the near-surface temperature rises significantly by about 3.84 °C, and the daily minimum temperature after deforestation becomes similar to the daily maximum temperature before deforestation. Except for wet-bulb temperature, human heat stress indicators shift to more severe levels, with implications for health and a significant reduction in work productivity. Finally, the mean 10 m wind speed intensifies by a factor of four, with the 99th percentile wind speed doubling. To summarize, our findings, while based on an idealized case, provide a stark warning of the effects of continuing deforestation of the Amazon. acknowledgement: AY acknowledges funding by the CLICCS centre of excellence subproject A3 funded by DFG. We thank the German Climate Computing Center DKRZ for providing computing resources and the Integrated Climate Data Center (ICDC), the Center for Earth System Research and Sustainability (CEN), University of Hamburg, for supporting the IMERG data. In addition, we would like to thank Jana Sillmann for suggesting the analysis of heat stress indices and Keno Riechers for providing a thorough internal review of the initial manuscript at the Max Planck Institute for Meteorology. Open Access funding is enabled and organized by Projekt DEAL. This research has been supported by the Deutsche Forschungsgemeinschaft (grant no. CLICCS 390683824 (A3)). The article processing charges for this open-access publication were covered by the Max Planck Society. article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Arim full_name: Yoon, Arim last_name: Yoon - first_name: Cathy full_name: Hohenegger, Cathy last_name: Hohenegger - first_name: Jiawei full_name: Bao, Jiawei id: bb9a7399-fefd-11ed-be3c-ae648fd1d160 last_name: Bao - first_name: Lukas full_name: Brunner, Lukas last_name: Brunner citation: ama: Yoon A, Hohenegger C, Bao J, Brunner L. Extreme events in the Amazon after deforestation. Earth System Dynamics. 2026;17(1):167-179. doi:10.5194/esd-17-167-2026 apa: Yoon, A., Hohenegger, C., Bao, J., & Brunner, L. (2026). Extreme events in the Amazon after deforestation. Earth System Dynamics. Copernicus GmbH. https://doi.org/10.5194/esd-17-167-2026 chicago: Yoon, Arim, Cathy Hohenegger, Jiawei Bao, and Lukas Brunner. “Extreme Events in the Amazon after Deforestation.” Earth System Dynamics. Copernicus GmbH, 2026. https://doi.org/10.5194/esd-17-167-2026. ieee: A. Yoon, C. Hohenegger, J. Bao, and L. Brunner, “Extreme events in the Amazon after deforestation,” Earth System Dynamics, vol. 17, no. 1. Copernicus GmbH, pp. 167–179, 2026. ista: Yoon A, Hohenegger C, Bao J, Brunner L. 2026. Extreme events in the Amazon after deforestation. Earth System Dynamics. 17(1), 167–179. mla: Yoon, Arim, et al. “Extreme Events in the Amazon after Deforestation.” Earth System Dynamics, vol. 17, no. 1, Copernicus GmbH, 2026, pp. 167–79, doi:10.5194/esd-17-167-2026. short: A. Yoon, C. Hohenegger, J. Bao, L. Brunner, Earth System Dynamics 17 (2026) 167–179. date_created: 2026-02-16T10:44:58Z date_published: 2026-02-04T00:00:00Z date_updated: 2026-02-23T10:28:48Z day: '04' ddc: - '550' department: - _id: CaMu doi: 10.5194/esd-17-167-2026 file: - access_level: open_access checksum: 6c3669c463731ad7c484b2990eb8ee0d content_type: application/pdf creator: dernst date_created: 2026-02-23T10:26:29Z date_updated: 2026-02-23T10:26:29Z file_id: '21348' file_name: 2026_EarthSystDynam_Yoon.pdf file_size: 2068229 relation: main_file success: 1 file_date_updated: 2026-02-23T10:26:29Z has_accepted_license: '1' intvolume: ' 17' issue: '1' language: - iso: eng month: '02' oa: 1 oa_version: Published Version page: 167-179 publication: Earth System Dynamics publication_identifier: eissn: - 2190-4987 publication_status: published publisher: Copernicus GmbH quality_controlled: '1' scopus_import: '1' status: public title: Extreme events in the Amazon after deforestation tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 17 year: '2026' ... --- OA_place: repository OA_type: green _id: '21242' abstract: - lang: eng text: We obtain an asymptotic formula for the number of integral solutions to a system of diagonal equations. We obtain an asymptotic formula for the number of solutions with variables restricted to smooth numbers as well. We improve the required number of variables compared to previous results by incorporating recent progress on Waring’s problem and the resolution of the main conjecture in Vinogradov’s mean value theorem. article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Nick full_name: Rome, Nick last_name: Rome - first_name: Shuntaro full_name: Yamagishi, Shuntaro id: 0c3fbc5c-f7a6-11ec-8d70-9485e75b416b last_name: Yamagishi citation: ama: Rome N, Yamagishi S. Integral solutions to systems of diagonal equations. Pacific Journal of Mathematics. 2026;340(1):179-198. doi:10.2140/pjm.2026.340.179 apa: Rome, N., & Yamagishi, S. (2026). Integral solutions to systems of diagonal equations. Pacific Journal of Mathematics. Mathematical Sciences Publishers. https://doi.org/10.2140/pjm.2026.340.179 chicago: Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal Equations.” Pacific Journal of Mathematics. Mathematical Sciences Publishers, 2026. https://doi.org/10.2140/pjm.2026.340.179. ieee: N. Rome and S. Yamagishi, “Integral solutions to systems of diagonal equations,” Pacific Journal of Mathematics, vol. 340, no. 1. Mathematical Sciences Publishers, pp. 179–198, 2026. ista: Rome N, Yamagishi S. 2026. Integral solutions to systems of diagonal equations. Pacific Journal of Mathematics. 340(1), 179–198. mla: Rome, Nick, and Shuntaro Yamagishi. “Integral Solutions to Systems of Diagonal Equations.” Pacific Journal of Mathematics, vol. 340, no. 1, Mathematical Sciences Publishers, 2026, pp. 179–98, doi:10.2140/pjm.2026.340.179. short: N. Rome, S. Yamagishi, Pacific Journal of Mathematics 340 (2026) 179–198. date_created: 2026-02-16T15:17:27Z date_published: 2026-01-01T00:00:00Z date_updated: 2026-02-17T11:43:14Z day: '01' department: - _id: TiBr doi: 10.2140/pjm.2026.340.179 external_id: arxiv: - '2406.09256' intvolume: ' 340' issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2406.09256 month: '01' oa: 1 oa_version: Preprint page: 179-198 publication: Pacific Journal of Mathematics publication_identifier: eissn: - 1945-5844 issn: - 0030-8730 publication_status: published publisher: Mathematical Sciences Publishers quality_controlled: '1' status: public title: Integral solutions to systems of diagonal equations type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 340 year: '2026' ... --- OA_place: repository OA_type: green _id: '21273' abstract: - lang: eng text: In this paper we examine how porosity fluctuations affect the hydrodynamic permeability of a porous matrix or membrane. We introduce a fluctuating Darcy model, which couples the Navier-Stokes equation to the space- and time-dependent porosity fluctuations via a Darcy friction term. Using a perturbative approach, a Dyson equation for hydrodynamic fluctuations is derived and solved to express the permeability in terms of the matrix fluctuation spectrum. Surprisingly, the model reveals strong modifications of the fluid permeability in fluctuating matrices compared to static ones. Applications to various matrix excitation models, the breathing matrix, phonons, and active forcing, highlight the significant influence of matrix fluctuations on fluid transport, offering insights for optimizing membrane design for separation applications. acknowledgement: "The authors acknowledge support from ERC project n-AQUA, Grant Agreement No. 101071937.\r\nB.C. and A.S. acknowledge support from the CFM Foundation. B.C. acknowledges support from\r\nthe NOMIS Foundation." article_number: '014201' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Albert full_name: Dombret, Albert last_name: Dombret - first_name: Adrien full_name: Sutter, Adrien last_name: Sutter - first_name: Baptiste full_name: Coquinot, Baptiste id: f8417bd4-f599-11ee-a482-b927e3ed1e8e last_name: Coquinot orcid: 0000-0001-5524-596X - first_name: Nikita full_name: Kavokine, Nikita last_name: Kavokine - first_name: Benoit full_name: Coasne, Benoit last_name: Coasne - first_name: Lydéric full_name: Bocquet, Lydéric last_name: Bocquet citation: ama: Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. Hydrodynamic permeability of fluctuating porous membranes. Physical Review Fluids. 2026;11(1). doi:10.1103/m8h6-1wfk apa: Dombret, A., Sutter, A., Coquinot, B., Kavokine, N., Coasne, B., & Bocquet, L. (2026). Hydrodynamic permeability of fluctuating porous membranes. Physical Review Fluids. American Physical Society. https://doi.org/10.1103/m8h6-1wfk chicago: Dombret, Albert, Adrien Sutter, Baptiste Coquinot, Nikita Kavokine, Benoit Coasne, and Lydéric Bocquet. “Hydrodynamic Permeability of Fluctuating Porous Membranes.” Physical Review Fluids. American Physical Society, 2026. https://doi.org/10.1103/m8h6-1wfk. ieee: A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, and L. Bocquet, “Hydrodynamic permeability of fluctuating porous membranes,” Physical Review Fluids, vol. 11, no. 1. American Physical Society, 2026. ista: Dombret A, Sutter A, Coquinot B, Kavokine N, Coasne B, Bocquet L. 2026. Hydrodynamic permeability of fluctuating porous membranes. Physical Review Fluids. 11(1), 014201. mla: Dombret, Albert, et al. “Hydrodynamic Permeability of Fluctuating Porous Membranes.” Physical Review Fluids, vol. 11, no. 1, 014201, American Physical Society, 2026, doi:10.1103/m8h6-1wfk. short: A. Dombret, A. Sutter, B. Coquinot, N. Kavokine, B. Coasne, L. Bocquet, Physical Review Fluids 11 (2026). corr_author: '1' date_created: 2026-02-17T08:10:09Z date_published: 2026-01-21T00:00:00Z date_updated: 2026-02-23T12:01:57Z day: '21' department: - _id: MiLe doi: 10.1103/m8h6-1wfk external_id: arxiv: - '2512.11368' intvolume: ' 11' issue: '1' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2512.11368 month: '01' oa: 1 oa_version: Preprint publication: Physical Review Fluids publication_identifier: eissn: - 2469-990X publication_status: published publisher: American Physical Society quality_controlled: '1' status: public title: Hydrodynamic permeability of fluctuating porous membranes type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 11 year: '2026' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '21275' abstract: - lang: eng text: DNA methylation is a primary layer of epigenetic modification that plays a pivotal role in the regulation of development, aging, and cancer. The concurrent activity of opposing enzymes that mediate DNA methylation and demethylation gives rise to a biochemical cycle and active turnover of DNA methylation. While the ensuing biochemical oscillations have been implicated in the regulation of cell differentiation, their functional role and spatiotemporal dynamics are unknown. In this work, we demonstrate that chromatin-mediated coupling between these local biochemical cycles can lead to the emergence of phase-locked domains, regions of locally synchronized turnover activity, whose coarsening is arrested by genomic heterogeneity. We introduce a minimal model based on stochastic oscillators with constrained long-range and nonreciprocal interactions, shaped by the local chromatin organization. Through a combination of analytical theory and stochastic simulations, we predict both the degree of synchronization and the typical size of emergent phase-locked domains. We qualitatively test these predictions using single-cell sequencing data. Our results show that DNA methylation turnover exhibits surprisingly rich spatiotemporal patterns that may be used by cells to control cell differentiation. acknowledgement: This project has received funding from the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 950349 and the Marie Skłodowska-Curie Grant Agreement No. 101034413. The computations in this paper were run in part on the the FASRC Cannon cluster supported by the FAS Division of Science Research Computing Group at Harvard University and the cluster of the Max Planck Institute for the Physics of Complex Systems. article_number: '013018' article_processing_charge: Yes article_type: original author: - first_name: Fabrizio full_name: Olmeda, Fabrizio id: 69dbf5fb-8a76-11ed-866b-fb486d8b5689 last_name: Olmeda - first_name: Misha full_name: Gupta, Misha last_name: Gupta - first_name: Onurcan full_name: Bektas, Onurcan last_name: Bektas - first_name: Steffen full_name: Rulands, Steffen last_name: Rulands citation: ama: Olmeda F, Gupta M, Bektas O, Rulands S. Spatiotemporal patterns of active epigenetic turnover. PRX Life. 2026;4. doi:10.1103/89bj-79g5 apa: Olmeda, F., Gupta, M., Bektas, O., & Rulands, S. (2026). Spatiotemporal patterns of active epigenetic turnover. PRX Life. American Physical Society. https://doi.org/10.1103/89bj-79g5 chicago: Olmeda, Fabrizio, Misha Gupta, Onurcan Bektas, and Steffen Rulands. “Spatiotemporal Patterns of Active Epigenetic Turnover.” PRX Life. American Physical Society, 2026. https://doi.org/10.1103/89bj-79g5. ieee: F. Olmeda, M. Gupta, O. Bektas, and S. Rulands, “Spatiotemporal patterns of active epigenetic turnover,” PRX Life, vol. 4. American Physical Society, 2026. ista: Olmeda F, Gupta M, Bektas O, Rulands S. 2026. Spatiotemporal patterns of active epigenetic turnover. PRX Life. 4, 013018. mla: Olmeda, Fabrizio, et al. “Spatiotemporal Patterns of Active Epigenetic Turnover.” PRX Life, vol. 4, 013018, American Physical Society, 2026, doi:10.1103/89bj-79g5. short: F. Olmeda, M. Gupta, O. Bektas, S. Rulands, PRX Life 4 (2026). corr_author: '1' date_created: 2026-02-17T08:17:53Z date_published: 2026-02-09T00:00:00Z date_updated: 2026-02-24T06:54:32Z day: '09' ddc: - '570' department: - _id: EdHa doi: 10.1103/89bj-79g5 ec_funded: 1 file: - access_level: open_access checksum: df9776422862d1d02c66d98e2d620849 content_type: application/pdf creator: dernst date_created: 2026-02-24T06:53:05Z date_updated: 2026-02-24T06:53:05Z file_id: '21351' file_name: 2026_PRXLife_Olmeda.pdf file_size: 5857833 relation: main_file success: 1 file_date_updated: 2026-02-24T06:53:05Z has_accepted_license: '1' intvolume: ' 4' language: - iso: eng month: '02' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: PRX Life publication_identifier: eissn: - 2835-8279 publication_status: published publisher: American Physical Society quality_controlled: '1' status: public title: Spatiotemporal patterns of active epigenetic turnover tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 4 year: '2026' ... --- DOAJ_listed: '1' OA_place: publisher OA_type: gold PlanS_conform: '1' _id: '21282' abstract: - lang: eng text: 'Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge autonomously through cellular interactions. We propose that both extremes—as well as the continuum of intermediate cases—can be conceptualized as information-processing systems, whose operation can be described using “Marr''s three levels of analysis”: the computational problem being solved, the algorithms employed, and their molecular implementation. At the first level, we argue that normative theories, such as information-theoretic optimization principles, provide a formalization of the computational problem. At the second level, we show how simplified information-processing architectures provide a framework for developmental algorithms, which are formalized mathematically using dynamical systems theory. At the third level, the implementation of developmental algorithms is described by mechanistic biophysical and gene regulatory network models.' acknowledgement: We thank Edouard Hannezo, Anna Kicheva, Fridtjof Brauns, and all members of the Brückner and Tkačik groups for feedback and inspiring discussions. This work was supported in part by European Research Council ERC-2023-SyG “Dynatrans” Grant No. 101118866 (G.T.). This work was conducted while visiting the Okinawa Institute of Science and Technology (OIST) through the Theoretical Sciences Visiting Program (TSVP); at the Kavli Institute for Theoretical Physics (KITP) Santa Barbara, supported by NSF Grant No. PHY-1748958 and the Gordon and Betty Moore Foundation Grant No. 2919.02; and at Lucullus, Vienna. article_number: '017001' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: David full_name: Brückner, David id: e1e86031-6537-11eb-953a-f7ab92be508d last_name: Brückner orcid: 0000-0001-7205-2975 - first_name: Gašper full_name: Tkačik, Gašper id: 3D494DCA-F248-11E8-B48F-1D18A9856A87 last_name: Tkačik orcid: 0000-0002-6699-1455 citation: ama: 'Brückner D, Tkačik G. Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. PRX Life. 2026;4. doi:10.1103/fdcf-dkws' apa: 'Brückner, D., & Tkačik, G. (2026). Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. PRX Life. American Physical Society. https://doi.org/10.1103/fdcf-dkws' chicago: 'Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic Development: Information, Dynamical Systems, Gene Networks.” PRX Life. American Physical Society, 2026. https://doi.org/10.1103/fdcf-dkws.' ieee: 'D. Brückner and G. Tkačik, “Marr’s three levels for embryonic development: Information, dynamical systems, gene networks,” PRX Life, vol. 4. American Physical Society, 2026.' ista: 'Brückner D, Tkačik G. 2026. Marr’s three levels for embryonic development: Information, dynamical systems, gene networks. PRX Life. 4, 017001.' mla: 'Brückner, David, and Gašper Tkačik. “Marr’s Three Levels for Embryonic Development: Information, Dynamical Systems, Gene Networks.” PRX Life, vol. 4, 017001, American Physical Society, 2026, doi:10.1103/fdcf-dkws.' short: D. Brückner, G. Tkačik, PRX Life 4 (2026). corr_author: '1' date_created: 2026-02-17T08:29:10Z date_published: 2026-01-23T00:00:00Z date_updated: 2026-02-24T07:00:16Z day: '23' ddc: - '570' department: - _id: GaTk doi: 10.1103/fdcf-dkws external_id: arxiv: - '2510.24536' file: - access_level: open_access checksum: 99ef02dd741c4536eeefd12d409d5269 content_type: application/pdf creator: dernst date_created: 2026-02-24T06:57:44Z date_updated: 2026-02-24T06:57:44Z file_id: '21352' file_name: 2026_PRXLife_Brueckner.pdf file_size: 1147994 relation: main_file success: 1 file_date_updated: 2026-02-24T06:57:44Z has_accepted_license: '1' intvolume: ' 4' language: - iso: eng month: '01' oa: 1 oa_version: Published Version project: - _id: 7bfe6a29-9f16-11ee-852c-c0da5e2045d9 grant_number: '101118866' name: 'Transcription in 4D: the dynamic interplay between chromatin architecture and gene expression in developing pseudo-embryos' publication: PRX Life publication_identifier: eissn: - 2835-8279 publication_status: published publisher: American Physical Society quality_controlled: '1' status: public title: 'Marr''s three levels for embryonic development: Information, dynamical systems, gene networks' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 4 year: '2026' ... --- OA_place: repository OA_type: free access _id: '21284' abstract: - lang: eng text: The advantageous characteristics attributed to the 19F nucleus have made it a popular target for NMR once again in recent years. Aside from solution NMR, an increasing number of studies have been conducted applying solid-state magic-angle-spinning NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and strong dipolar couplings can be utilized to get structural insights into proteins and measure long distances. Despite increasing popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and 13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially reduces measurement times of 19F MAS NMR experiments without compromising resolution. Additionally, we report the chemical-shift assignments of all four fluorotryptophan signals in the 12 × 39 kDa large protein using a mutagenesis approach. acknowledged_ssus: - _id: NMR - _id: LifeSc acknowledgement: We thank Ben P. Tatman for insightful discussions. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support Facility. article_processing_charge: No author: - first_name: Lea Marie full_name: Becker, Lea Marie id: 36336939-eb97-11eb-a6c2-c83f1214ca79 last_name: Becker orcid: 0000-0002-6401-5151 - first_name: Paul full_name: Schanda, Paul id: 7B541462-FAF6-11E9-A490-E8DFE5697425 last_name: Schanda orcid: 0000-0002-9350-7606 citation: ama: Becker LM, Schanda P. Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” 2026. doi:10.15479/AT-ISTA-21284 apa: Becker, L. M., & Schanda, P. (2026). Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” Institute of Science and Technology Austria. https://doi.org/10.15479/AT-ISTA-21284 chicago: Becker, Lea Marie, and Paul Schanda. “Research Data for ‘Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.’” Institute of Science and Technology Austria, 2026. https://doi.org/10.15479/AT-ISTA-21284. ieee: L. M. Becker and P. Schanda, “Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.’” Institute of Science and Technology Austria, 2026. ista: Becker LM, Schanda P. 2026. Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants’, Institute of Science and Technology Austria, 10.15479/AT-ISTA-21284. mla: Becker, Lea Marie, and Paul Schanda. Research Data for “Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.” Institute of Science and Technology Austria, 2026, doi:10.15479/AT-ISTA-21284. short: L.M. Becker, P. Schanda, (2026). contributor: - contributor_type: researcher first_name: Giorgia id: 334a5e40-8747-11f0-b671-ba1f5154b4b4 last_name: Toscano - contributor_type: researcher first_name: Anna id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471 last_name: Kapitonova - contributor_type: researcher first_name: Rajkumar id: a3089acd-6806-11ee-bacc-f0c7d500ad20 last_name: Singh - contributor_type: researcher first_name: Undina id: bb74f472-ae54-11eb-9835-bc9c22fb1183 last_name: Guillerm - contributor_type: researcher first_name: Roman last_name: Lichtenecker corr_author: '1' date_created: 2026-02-17T10:17:14Z date_published: 2026-02-18T00:00:00Z date_updated: 2026-02-18T10:12:49Z day: '18' ddc: - '541' department: - _id: GradSch - _id: PaSc doi: 10.15479/AT-ISTA-21284 file: - access_level: open_access checksum: 2d3105f26be578073b88ee1f2ea0bdb1 content_type: application/zip creator: lbecker date_created: 2026-02-17T10:11:14Z date_updated: 2026-02-17T10:11:14Z file_id: '21285' file_name: Research_data.zip file_size: 36996027 relation: main_file success: 1 - access_level: open_access checksum: e24aebcdb8856cb181cbaa02de020ddb content_type: text/plain creator: lbecker date_created: 2026-02-17T10:11:14Z date_updated: 2026-02-17T10:11:14Z file_id: '21286' file_name: README.txt file_size: 1993 relation: table_of_contents file_date_updated: 2026-02-17T10:11:14Z has_accepted_license: '1' month: '2' oa: 1 oa_version: None publisher: Institute of Science and Technology Austria status: public title: Research data for "Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants" tmp: image: /images/cc_by_nc.png legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) short: CC BY-NC (4.0) type: research_data user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d year: '2026' ... --- OA_place: repository OA_type: green _id: '21290' abstract: - lang: eng text: Gene duplication underlies evolutionary innovation, yet many paralogues remain highly similar, raising questions about their functional divergence and physiological relevance. The spliceosomal Sm core protein SNRPB and its mammalian-specific paralogue SNRPN share over 90% sequence identity, but their distinct expression patterns - SNRPB being ubiquitous and SNRPN confined to the brain - suggest specialized functions. Why mammals have two different spliceosomes has remained obscure. Here, we generated isogenic human cell lines expressing ectopically either SNRPB or SNRPN exclusively and found that SNRPN stabilizes transcripts involved in energy metabolism and mitochondrial function, leading to increased mitochondrial abundance and oxygen consumption. Despite similar spliceosomal interactomes, SNRPN more strongly associates with the PRMT5 methylosome complex and exhibits dynamic arginine methylation in its C-terminal region that is sensitive to translation inhibition and amino acid availability. The SNRPN-dependent transcriptome responds to translation inhibition by stabilizing long, intron-rich genes involved in amino acid and energy metabolism. Our findings reveal a nutrient-sensitive, methylation-dependent mechanism that differentiates the two paralogues. This suggests that SNRPN functions as a metabolic-specialized spliceosomal subunit thereby providing tissue-specific adaptation of RNA processing in mammals. acknowledgement: "We thank Oliver Mühlemann and Alex Hofer (University of Bern) for sharing SMG inhibitors\r\nand for their expertise in nonsense-mediated mRNA decay and Maria Hondele for critical\r\nreading of the manuscript draft. We also thank the IMB Genomics Core Facility for assistance\r\nwith library preparation and sequencing, Martin Möckel and the IMB Protein Production Core\r\nFacility for providing enzymes used in this work, Marton Gelleri together with the IMB\r\nMicroscopy Core Facility for support with microscopy and FRAP experiments, Jasmin Cartano\r\nfor proteomics sample processing and the IMB Flow Cytometry Core Facility for support. In\r\naddition, we thank the Imaging Core Facility (IMCF) and the FACS Core Facility at the\r\nBiozentrum, University of Basel, for technical assistance. CIKV acknowledges funding by the\r\nDeutsche Forschungsgemeinschaft (DFG, German Research Foundation) - Individual Grant\r\nProject no. 513744403, Scientific Network Grant Project no. 531902894, GRK2526 “Genevo”\r\n- Project no. 407023052”, GRK2859 (“4R”) - Project no. 491145305, Forschungsinitiative\r\nRheinland-Pfalz (ReALity), the EMBO Young Investigator Program (5795), institutional\r\nfunding from the Institute of Molecular Biology and funds from the Kanton Basel-Stadt and\r\nBasel-Land provided to the Biozentrum of the University Basel. J.H.G.F.G. was part of the\r\n‘Science of Healthy Ageing Research Programme’ (SHARP) initiative funded by RhinelandPalatinate’s Ministry of Science, Education and Culture. PR is funded by the Biozentrum PhD\r\nFellowships Program. MFB received financial support from the intramural High Potentials\r\nGrant program of the University Medical Center Mainz, Forschungsinitiative Rheinland-Pfalz\r\n(ReALity) and Stiftungen zugunsten der Medizinischen Fakultät der LMU Klinikum (26069).\r\nInstruments in the IMB core facilities were supported by funds from the DFG: Laser Scanning\r\nConfocal (Leica Stellaris 8 Falcon, funded by the DFG - Project #497669232), Orbitrap Astral system (funded by the DFG - Project #524805621) and BD LSRFortessa SOPR is funded by\r\nthe DFG - Project #210253511.\r\n" article_processing_charge: No author: - first_name: Feyza full_name: Polat Haas, Feyza last_name: Polat Haas - first_name: Ana full_name: Villalba Requena, Ana id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247 last_name: Villalba Requena orcid: 0000-0002-5615-5277 - first_name: Polina full_name: Rusina, Polina last_name: Rusina - first_name: Anusha full_name: Gopalan, Anusha last_name: Gopalan - first_name: Hector full_name: Fritz, Hector last_name: Fritz - first_name: Azamat full_name: Akhmetkaliyev, Azamat last_name: Akhmetkaliyev - first_name: Frank full_name: Ruehle, Frank last_name: Ruehle - first_name: Anna full_name: Einsiedel, Anna last_name: Einsiedel - first_name: Anna full_name: Szczepinska, Anna last_name: Szczepinska - first_name: Fridolin full_name: Kielisch, Fridolin last_name: Kielisch - first_name: Jia-Xuan full_name: Chen, Jia-Xuan last_name: Chen - first_name: Susanne full_name: Nguyen, Susanne last_name: Nguyen - first_name: Thierry full_name: Schmidlin, Thierry last_name: Schmidlin - first_name: Simon full_name: Hippenmeyer, Simon id: 37B36620-F248-11E8-B48F-1D18A9856A87 last_name: Hippenmeyer orcid: 0000-0003-2279-1061 - first_name: M. Felicia full_name: Bailicata, M. Felicia last_name: Bailicata - first_name: Claudia Isabelle full_name: Keller Valsecchi, Claudia Isabelle last_name: Keller Valsecchi citation: ama: Polat Haas F, Villalba Requena A, Rusina P, et al. The splicing paralogues SNRPB and SNRPN control differential metabolic states. bioRxiv. doi:10.64898/2026.02.11.705284 apa: Polat Haas, F., Villalba Requena, A., Rusina, P., Gopalan, A., Fritz, H., Akhmetkaliyev, A., … Keller Valsecchi, C. I. (n.d.). The splicing paralogues SNRPB and SNRPN control differential metabolic states. bioRxiv. https://doi.org/10.64898/2026.02.11.705284 chicago: Polat Haas, Feyza, Ana Villalba Requena, Polina Rusina, Anusha Gopalan, Hector Fritz, Azamat Akhmetkaliyev, Frank Ruehle, et al. “The Splicing Paralogues SNRPB and SNRPN Control Differential Metabolic States.” BioRxiv, n.d. https://doi.org/10.64898/2026.02.11.705284. ieee: F. Polat Haas et al., “The splicing paralogues SNRPB and SNRPN control differential metabolic states.,” bioRxiv. . ista: Polat Haas F, Villalba Requena A, Rusina P, Gopalan A, Fritz H, Akhmetkaliyev A, Ruehle F, Einsiedel A, Szczepinska A, Kielisch F, Chen J-X, Nguyen S, Schmidlin T, Hippenmeyer S, Bailicata MF, Keller Valsecchi CI. The splicing paralogues SNRPB and SNRPN control differential metabolic states. bioRxiv, 10.64898/2026.02.11.705284. mla: Polat Haas, Feyza, et al. “The Splicing Paralogues SNRPB and SNRPN Control Differential Metabolic States.” BioRxiv, doi:10.64898/2026.02.11.705284. short: F. Polat Haas, A. Villalba Requena, P. Rusina, A. Gopalan, H. Fritz, A. Akhmetkaliyev, F. Ruehle, A. Einsiedel, A. Szczepinska, F. Kielisch, J.-X. Chen, S. Nguyen, T. Schmidlin, S. Hippenmeyer, M.F. Bailicata, C.I. Keller Valsecchi, BioRxiv (n.d.). date_created: 2026-02-17T11:35:59Z date_published: 2026-02-11T00:00:00Z date_updated: 2026-02-23T11:03:33Z day: '11' department: - _id: SiHi doi: 10.64898/2026.02.11.705284 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.64898/2026.02.11.705284 month: '02' oa: 1 oa_version: Preprint publication: bioRxiv publication_status: submitted status: public title: The splicing paralogues SNRPB and SNRPN control differential metabolic states. type: preprint user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ... --- OA_place: publisher OA_type: hybrid PlanS_conform: '1' _id: '21295' abstract: - lang: eng text: 'Depending on the type of flow, the transition to turbulence can take one of two forms: either turbulence arises from a sequence of instabilities or from the spatial proliferation of transiently chaotic domains, a process analogous to directed percolation. The former scenario is commonly referred to as a supercritical transition and frequently encountered in flows destabilized by body forces, whereas the latter subcritical transition is common in shear flows. Both cases are inherently continuous in a sense that the transformation from ordered laminar to fully turbulent fluid motion is only accomplished gradually with flow speed. Here we show that these established transition types do not account for the more general setting of shear flows subject to body forces. The combination of the two continuous scenarios leads to the attenuation of spatial coupling; with increasing forcing amplitude, the transition becomes increasingly sharp and eventually discontinuous. We argue that the suppression of laminar–turbulent coexistence and the approach towards a discontinuous phase transition potentially apply to a broad range of situations including flows subject to, for example, buoyancy, centrifugal or electromagnetic forces.' acknowledgement: The work was supported by the Simons Foundation (grant number 662960, to B.H.). Open access funding provided by Institute of Science and Technology (IST Austria). article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Bowen full_name: Yang, Bowen id: 71b6ff4b-15b2-11ec-abd3-aef6b028cf7e last_name: Yang orcid: 0000-0002-4843-6853 - first_name: Yi full_name: Zhuang, Yi id: 3677B57C-F248-11E8-B48F-1D18A9856A87 last_name: Zhuang - first_name: Gökhan full_name: Yalniz, Gökhan id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425 last_name: Yalniz orcid: 0000-0002-8490-9312 - first_name: Mukund full_name: Vasudevan, Mukund id: 3C5A959A-F248-11E8-B48F-1D18A9856A87 last_name: Vasudevan - first_name: Elena full_name: Marensi, Elena id: 0BE7553A-1004-11EA-B805-18983DDC885E last_name: Marensi orcid: 0000-0001-7173-4923 - first_name: Björn full_name: Hof, Björn id: 3A374330-F248-11E8-B48F-1D18A9856A87 last_name: Hof orcid: 0000-0003-2057-2754 citation: ama: Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. Discontinuous transition to shear flow turbulence. Nature Physics. 2026. doi:10.1038/s41567-025-03166-3 apa: Yang, B., Zhuang, Y., Yalniz, G., Vasudevan, M., Marensi, E., & Hof, B. (2026). Discontinuous transition to shear flow turbulence. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-025-03166-3 chicago: Yang, Bowen, Yi Zhuang, Gökhan Yalniz, Mukund Vasudevan, Elena Marensi, and Björn Hof. “Discontinuous Transition to Shear Flow Turbulence.” Nature Physics. Springer Nature, 2026. https://doi.org/10.1038/s41567-025-03166-3. ieee: B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, and B. Hof, “Discontinuous transition to shear flow turbulence,” Nature Physics. Springer Nature, 2026. ista: Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. 2026. Discontinuous transition to shear flow turbulence. Nature Physics. mla: Yang, Bowen, et al. “Discontinuous Transition to Shear Flow Turbulence.” Nature Physics, Springer Nature, 2026, doi:10.1038/s41567-025-03166-3. short: B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, B. Hof, Nature Physics (2026). corr_author: '1' date_created: 2026-02-17T11:38:41Z date_published: 2026-02-17T00:00:00Z date_updated: 2026-02-23T11:36:46Z day: '17' ddc: - '532' department: - _id: GradSch - _id: BjHo doi: 10.1038/s41567-025-03166-3 external_id: arxiv: - '2311.11474' has_accepted_license: '1' language: - iso: eng month: '02' oa_version: Published Version project: - _id: 238598C6-32DE-11EA-91FC-C7463DDC885E grant_number: '662960' name: Revisiting the Turbulence Problem Using Statistical Mechanics publication: Nature Physics publication_identifier: eissn: - 1745-2481 issn: - 1745-2473 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Discontinuous transition to shear flow turbulence tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2026' ...