---
_id: '6366'
abstract:
- lang: eng
text: Plants have a remarkable capacity to adjust their growth and development to
elevated ambient temperatures. Increased elongation growth of roots, hypocotyls
and petioles in warm temperatures are hallmarks of seedling thermomorphogenesis.
In the last decade, significant progress has been made to identify the molecular
signaling components regulating these growth responses. Increased ambient temperature
utilizes diverse components of the light sensing and signal transduction network
to trigger growth adjustments. However, it remains unknown whether temperature
sensing and responses are universal processes that occur uniformly in all plant
organs. Alternatively, temperature sensing may be confined to specific tissues
or organs, which would require a systemic signal that mediates responses in distal
parts of the plant. Here we show that Arabidopsis (Arabidopsis thaliana) seedlings
show organ-specific transcriptome responses to elevated temperatures, and that
thermomorphogenesis involves both autonomous and organ-interdependent temperature
sensing and signaling. Seedling roots can sense and respond to temperature in
a shoot-independent manner, whereas shoot temperature responses require both local
and systemic processes. The induction of cell elongation in hypocotyls requires
temperature sensing in cotyledons, followed by generation of a mobile auxin signal.
Subsequently, auxin travels to the hypocotyl where it triggers local brassinosteroid-induced
cell elongation in seedling stems, which depends upon a distinct, permissive temperature
sensor in the hypocotyl.
article_processing_charge: No
article_type: original
author:
- first_name: Julia
full_name: Bellstaedt, Julia
last_name: Bellstaedt
- first_name: Jana
full_name: Trenner, Jana
last_name: Trenner
- first_name: Rebecca
full_name: Lippmann, Rebecca
last_name: Lippmann
- first_name: Yvonne
full_name: Poeschl, Yvonne
last_name: Poeschl
- first_name: Xixi
full_name: Zhang, Xixi
id: 61A66458-47E9-11EA-85BA-8AEAAF14E49A
last_name: Zhang
orcid: 0000-0001-7048-4627
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Marcel
full_name: Quint, Marcel
last_name: Quint
- first_name: Carolin
full_name: Delker, Carolin
last_name: Delker
citation:
ama: Bellstaedt J, Trenner J, Lippmann R, et al. A mobile auxin signal connects
temperature sensing in cotyledons with growth responses in hypocotyls. Plant
Physiology. 2019;180(2):757-766. doi:10.1104/pp.18.01377
apa: Bellstaedt, J., Trenner, J., Lippmann, R., Poeschl, Y., Zhang, X., Friml, J.,
… Delker, C. (2019). A mobile auxin signal connects temperature sensing in cotyledons
with growth responses in hypocotyls. Plant Physiology. ASPB. https://doi.org/10.1104/pp.18.01377
chicago: Bellstaedt, Julia, Jana Trenner, Rebecca Lippmann, Yvonne Poeschl, Xixi
Zhang, Jiří Friml, Marcel Quint, and Carolin Delker. “A Mobile Auxin Signal Connects
Temperature Sensing in Cotyledons with Growth Responses in Hypocotyls.” Plant
Physiology. ASPB, 2019. https://doi.org/10.1104/pp.18.01377.
ieee: J. Bellstaedt et al., “A mobile auxin signal connects temperature sensing
in cotyledons with growth responses in hypocotyls,” Plant Physiology, vol.
180, no. 2. ASPB, pp. 757–766, 2019.
ista: Bellstaedt J, Trenner J, Lippmann R, Poeschl Y, Zhang X, Friml J, Quint M,
Delker C. 2019. A mobile auxin signal connects temperature sensing in cotyledons
with growth responses in hypocotyls. Plant Physiology. 180(2), 757–766.
mla: Bellstaedt, Julia, et al. “A Mobile Auxin Signal Connects Temperature Sensing
in Cotyledons with Growth Responses in Hypocotyls.” Plant Physiology, vol.
180, no. 2, ASPB, 2019, pp. 757–66, doi:10.1104/pp.18.01377.
short: J. Bellstaedt, J. Trenner, R. Lippmann, Y. Poeschl, X. Zhang, J. Friml, M.
Quint, C. Delker, Plant Physiology 180 (2019) 757–766.
date_created: 2019-04-30T15:24:22Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2026-06-18T19:03:49Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1104/pp.18.01377
external_id:
isi:
- '000470086100019'
pmid:
- '31000634'
intvolume: ' 180'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: www.doi.org/10.1104/pp.18.01377
month: '06'
oa: 1
oa_version: Published Version
page: 757-766
pmid: 1
publication: Plant Physiology
publication_identifier:
eissn:
- 1532-2548
issn:
- 0032-0889
publication_status: published
publisher: ASPB
quality_controlled: '1'
scopus_import: '1'
status: public
title: A mobile auxin signal connects temperature sensing in cotyledons with growth
responses in hypocotyls
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 180
year: '2019'
...
---
_id: '6377'
abstract:
- lang: eng
text: Clathrin-mediated endocytosis (CME) is a highly conserved and essential cellular
process in eukaryotic cells, but its dynamic and vital nature makes it challenging
to study using classical genetics tools. In contrast, although small molecules
can acutely and reversibly perturb CME, the few chemical CME inhibitors that have
been applied to plants are either ineffective or show undesirable side effects.
Here, we identify the previously described endosidin9 (ES9) as an inhibitor of
clathrin heavy chain (CHC) function in both Arabidopsis and human cells through
affinity-based target isolation, in vitro binding studies and X-ray crystallography.
Moreover, we present a chemically improved ES9 analog, ES9-17, which lacks the
undesirable side effects of ES9 while retaining the ability to target CHC. ES9
and ES9-17 have expanded the chemical toolbox used to probe CHC function, and
present chemical scaffolds for further design of more specific and potent CHC
inhibitors across different systems.
article_processing_charge: No
article_type: original
author:
- first_name: Wim
full_name: Dejonghe, Wim
last_name: Dejonghe
- first_name: Isha
full_name: Sharma, Isha
last_name: Sharma
- first_name: Bram
full_name: Denoo, Bram
last_name: Denoo
- first_name: Steven
full_name: De Munck, Steven
last_name: De Munck
- first_name: Qing
full_name: Lu, Qing
last_name: Lu
- first_name: Kiril
full_name: Mishev, Kiril
last_name: Mishev
- first_name: Haydar
full_name: Bulut, Haydar
last_name: Bulut
- first_name: Evelien
full_name: Mylle, Evelien
last_name: Mylle
- first_name: Riet
full_name: De Rycke, Riet
last_name: De Rycke
- first_name: Mina K
full_name: Vasileva, Mina K
id: 3407EB18-F248-11E8-B48F-1D18A9856A87
last_name: Vasileva
- first_name: Daniel V.
full_name: Savatin, Daniel V.
last_name: Savatin
- first_name: Wim
full_name: Nerinckx, Wim
last_name: Nerinckx
- first_name: An
full_name: Staes, An
last_name: Staes
- first_name: Andrzej
full_name: Drozdzecki, Andrzej
last_name: Drozdzecki
- first_name: Dominique
full_name: Audenaert, Dominique
last_name: Audenaert
- first_name: Klaas
full_name: Yperman, Klaas
last_name: Yperman
- first_name: Annemieke
full_name: Madder, Annemieke
last_name: Madder
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Daniël
full_name: Van Damme, Daniël
last_name: Van Damme
- first_name: Kris
full_name: Gevaert, Kris
last_name: Gevaert
- first_name: Volker
full_name: Haucke, Volker
last_name: Haucke
- first_name: Savvas N.
full_name: Savvides, Savvas N.
last_name: Savvides
- first_name: Johan
full_name: Winne, Johan
last_name: Winne
- first_name: Eugenia
full_name: Russinova, Eugenia
last_name: Russinova
citation:
ama: Dejonghe W, Sharma I, Denoo B, et al. Disruption of endocytosis through chemical
inhibition of clathrin heavy chain function. Nature Chemical Biology. 2019;15(6):641–649.
doi:10.1038/s41589-019-0262-1
apa: Dejonghe, W., Sharma, I., Denoo, B., De Munck, S., Lu, Q., Mishev, K., … Russinova,
E. (2019). Disruption of endocytosis through chemical inhibition of clathrin heavy
chain function. Nature Chemical Biology. Springer Nature. https://doi.org/10.1038/s41589-019-0262-1
chicago: Dejonghe, Wim, Isha Sharma, Bram Denoo, Steven De Munck, Qing Lu, Kiril
Mishev, Haydar Bulut, et al. “Disruption of Endocytosis through Chemical Inhibition
of Clathrin Heavy Chain Function.” Nature Chemical Biology. Springer Nature,
2019. https://doi.org/10.1038/s41589-019-0262-1.
ieee: W. Dejonghe et al., “Disruption of endocytosis through chemical inhibition
of clathrin heavy chain function,” Nature Chemical Biology, vol. 15, no.
6. Springer Nature, pp. 641–649, 2019.
ista: Dejonghe W, Sharma I, Denoo B, De Munck S, Lu Q, Mishev K, Bulut H, Mylle
E, De Rycke R, Vasileva MK, Savatin DV, Nerinckx W, Staes A, Drozdzecki A, Audenaert
D, Yperman K, Madder A, Friml J, Van Damme D, Gevaert K, Haucke V, Savvides SN,
Winne J, Russinova E. 2019. Disruption of endocytosis through chemical inhibition
of clathrin heavy chain function. Nature Chemical Biology. 15(6), 641–649.
mla: Dejonghe, Wim, et al. “Disruption of Endocytosis through Chemical Inhibition
of Clathrin Heavy Chain Function.” Nature Chemical Biology, vol. 15, no.
6, Springer Nature, 2019, pp. 641–649, doi:10.1038/s41589-019-0262-1.
short: W. Dejonghe, I. Sharma, B. Denoo, S. De Munck, Q. Lu, K. Mishev, H. Bulut,
E. Mylle, R. De Rycke, M.K. Vasileva, D.V. Savatin, W. Nerinckx, A. Staes, A.
Drozdzecki, D. Audenaert, K. Yperman, A. Madder, J. Friml, D. Van Damme, K. Gevaert,
V. Haucke, S.N. Savvides, J. Winne, E. Russinova, Nature Chemical Biology 15 (2019)
641–649.
date_created: 2019-05-05T21:59:11Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2026-04-08T13:54:44Z
day: '01'
department:
- _id: JiFr
doi: 10.1038/s41589-019-0262-1
external_id:
isi:
- '000468195600018'
intvolume: ' 15'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 641–649
publication: Nature Chemical Biology
publication_identifier:
eissn:
- 1552-4469
issn:
- 1552-4450
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '7172'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Disruption of endocytosis through chemical inhibition of clathrin heavy chain
function
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2019'
...
---
_id: '6412'
abstract:
- lang: eng
text: Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance
of cell fate. The Polycomb Repressive Complexes PRC1 and PRC2 catalyse distinct
chromatin modifications to enforce gene silencing, but how transcriptional repression
is propagated through mitotic cell divisions remains a key unresolved question.
Using reversible tethering of PcG proteins to ectopic sites in mouse embryonic
stem cells, here we show that PRC1 can trigger transcriptional repression and
Polycomb-dependent chromatin modifications. We find that canonical PRC1 (cPRC1),
but not variant PRC1, maintains gene silencing through cell division upon reversal
of tethering. Propagation of gene repression is sustained by cis-acting histone
modifications, PRC2-mediated H3K27me3 and cPRC1-mediated H2AK119ub1, promoting
a sequence-independent feedback mechanism for PcG protein recruitment. Thus, the
distinct PRC1 complexes present in vertebrates can differentially regulate epigenetic
maintenance of gene silencing, potentially enabling dynamic heritable responses
to complex stimuli. Our findings reveal how PcG repression is potentially inherited
in vertebrates.
article_number: '1931'
article_processing_charge: No
author:
- first_name: Hagar F.
full_name: Moussa, Hagar F.
last_name: Moussa
- first_name: Daniel
full_name: Bsteh, Daniel
last_name: Bsteh
- first_name: Ramesh
full_name: Yelagandula, Ramesh
last_name: Yelagandula
- first_name: Carina
full_name: Pribitzer, Carina
last_name: Pribitzer
- first_name: Karin
full_name: Stecher, Karin
last_name: Stecher
- first_name: Katarina
full_name: Bartalska, Katarina
id: 4D883232-F248-11E8-B48F-1D18A9856A87
last_name: Bartalska
- first_name: Luca
full_name: Michetti, Luca
last_name: Michetti
- first_name: Jingkui
full_name: Wang, Jingkui
last_name: Wang
- first_name: Jorge A.
full_name: Zepeda-Martinez, Jorge A.
last_name: Zepeda-Martinez
- first_name: Ulrich
full_name: Elling, Ulrich
last_name: Elling
- first_name: Jacob I.
full_name: Stuckey, Jacob I.
last_name: Stuckey
- first_name: Lindsey I.
full_name: James, Lindsey I.
last_name: James
- first_name: Stephen V.
full_name: Frye, Stephen V.
last_name: Frye
- first_name: Oliver
full_name: Bell, Oliver
last_name: Bell
citation:
ama: Moussa HF, Bsteh D, Yelagandula R, et al. Canonical PRC1 controls sequence-independent
propagation of Polycomb-mediated gene silencing. Nature Communications.
2019;10(1). doi:10.1038/s41467-019-09628-6
apa: Moussa, H. F., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska,
K., … Bell, O. (2019). Canonical PRC1 controls sequence-independent propagation
of Polycomb-mediated gene silencing. Nature Communications. Springer Nature.
https://doi.org/10.1038/s41467-019-09628-6
chicago: Moussa, Hagar F., Daniel Bsteh, Ramesh Yelagandula, Carina Pribitzer, Karin
Stecher, Katarina Bartalska, Luca Michetti, et al. “Canonical PRC1 Controls Sequence-Independent
Propagation of Polycomb-Mediated Gene Silencing.” Nature Communications.
Springer Nature, 2019. https://doi.org/10.1038/s41467-019-09628-6.
ieee: H. F. Moussa et al., “Canonical PRC1 controls sequence-independent
propagation of Polycomb-mediated gene silencing,” Nature Communications,
vol. 10, no. 1. Springer Nature, 2019.
ista: Moussa HF, Bsteh D, Yelagandula R, Pribitzer C, Stecher K, Bartalska K, Michetti
L, Wang J, Zepeda-Martinez JA, Elling U, Stuckey JI, James LI, Frye SV, Bell O.
2019. Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated
gene silencing. Nature Communications. 10(1), 1931.
mla: Moussa, Hagar F., et al. “Canonical PRC1 Controls Sequence-Independent Propagation
of Polycomb-Mediated Gene Silencing.” Nature Communications, vol. 10, no.
1, 1931, Springer Nature, 2019, doi:10.1038/s41467-019-09628-6.
short: H.F. Moussa, D. Bsteh, R. Yelagandula, C. Pribitzer, K. Stecher, K. Bartalska,
L. Michetti, J. Wang, J.A. Zepeda-Martinez, U. Elling, J.I. Stuckey, L.I. James,
S.V. Frye, O. Bell, Nature Communications 10 (2019).
date_created: 2019-05-13T07:58:35Z
date_published: 2019-04-29T00:00:00Z
date_updated: 2026-04-03T09:38:23Z
day: '29'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1038/s41467-019-09628-6
external_id:
isi:
- '000466118700002'
file:
- access_level: open_access
checksum: 6550a328335396c856db4cbdda7d2994
content_type: application/pdf
creator: dernst
date_created: 2019-05-14T08:45:51Z
date_updated: 2020-07-14T12:47:29Z
file_id: '6448'
file_name: 2019_NatureComm_Moussa.pdf
file_size: 1223647
relation: main_file
file_date_updated: 2020-07-14T12:47:29Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Nature Communications
publication_identifier:
eissn:
- 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated
gene silencing
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 10
year: '2019'
...
---
_id: '6413'
abstract:
- lang: eng
text: Phase-field methods have long been used to model the flow of immiscible fluids.
Their ability to naturally capture interface topological changes is widely recognized,
but their accuracy in simulating flows of real fluids in practical geometries
is not established. We here quantitatively investigate the convergence of the
phase-field method to the sharp-interface limit with simulations of two-phase
pipe flow. We focus on core-annular flows, in which a highly viscous fluid is
lubricated by a less viscous fluid, and validate our simulations with an analytic
laminar solution, a formal linear stability analysis and also in the fully nonlinear
regime. We demonstrate the ability of the phase-field method to accurately deal
with non-rectangular geometry, strong advection, unsteady fluctuations and large
viscosity contrast. We argue that phase-field methods are very promising for quantitatively
studying moderately turbulent flows, especially at high concentrations of the
disperse phase.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Baofang
full_name: Song, Baofang
last_name: Song
- first_name: Carlos
full_name: Plana, Carlos
last_name: Plana
- first_name: Jose M
full_name: Lopez Alonso, Jose M
id: 40770848-F248-11E8-B48F-1D18A9856A87
last_name: Lopez Alonso
orcid: 0000-0002-0384-2022
- first_name: Marc
full_name: Avila, Marc
last_name: Avila
citation:
ama: Song B, Plana C, Lopez Alonso JM, Avila M. Phase-field simulation of core-annular
pipe flow. International Journal of Multiphase Flow. 2019;117:14-24. doi:10.1016/j.ijmultiphaseflow.2019.04.027
apa: Song, B., Plana, C., Lopez Alonso, J. M., & Avila, M. (2019). Phase-field
simulation of core-annular pipe flow. International Journal of Multiphase Flow.
Elsevier. https://doi.org/10.1016/j.ijmultiphaseflow.2019.04.027
chicago: Song, Baofang, Carlos Plana, Jose M Lopez Alonso, and Marc Avila. “Phase-Field
Simulation of Core-Annular Pipe Flow.” International Journal of Multiphase
Flow. Elsevier, 2019. https://doi.org/10.1016/j.ijmultiphaseflow.2019.04.027.
ieee: B. Song, C. Plana, J. M. Lopez Alonso, and M. Avila, “Phase-field simulation
of core-annular pipe flow,” International Journal of Multiphase Flow, vol.
117. Elsevier, pp. 14–24, 2019.
ista: Song B, Plana C, Lopez Alonso JM, Avila M. 2019. Phase-field simulation of
core-annular pipe flow. International Journal of Multiphase Flow. 117, 14–24.
mla: Song, Baofang, et al. “Phase-Field Simulation of Core-Annular Pipe Flow.” International
Journal of Multiphase Flow, vol. 117, Elsevier, 2019, pp. 14–24, doi:10.1016/j.ijmultiphaseflow.2019.04.027.
short: B. Song, C. Plana, J.M. Lopez Alonso, M. Avila, International Journal of
Multiphase Flow 117 (2019) 14–24.
date_created: 2019-05-13T07:58:35Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2026-04-16T09:49:27Z
day: '01'
department:
- _id: BjHo
doi: 10.1016/j.ijmultiphaseflow.2019.04.027
external_id:
arxiv:
- '1902.07351'
isi:
- '000474496000002'
intvolume: ' 117'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1902.07351
month: '08'
oa: 1
oa_version: Preprint
page: 14-24
publication: International Journal of Multiphase Flow
publication_identifier:
issn:
- 0301-9322
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Phase-field simulation of core-annular pipe flow
type: journal_article
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 117
year: '2019'
...
---
_id: '6415'
abstract:
- lang: eng
text: Ant invasions are often harmful to native species communities. Their pathogens
and host disease defense mechanisms may be one component of their devastating
success. First, they can introduce harmful diseases to their competitors in the
introduced range, to which they themselves are tolerant. Second, their supercolonial
social structure of huge multi-queen nest networks means that they will harbor
a broad pathogen spectrum and high pathogen load while remaining resilient, unlike
the smaller, territorial colonies of the native species. Thus, it is likely that
invasive ants act as a disease reservoir, promoting their competitive advantage
and invasive success.
article_processing_charge: No
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
citation:
ama: Cremer S. Pathogens and disease defense of invasive ants. Current Opinion
in Insect Science. 2019;33:63-68. doi:10.1016/j.cois.2019.03.011
apa: Cremer, S. (2019). Pathogens and disease defense of invasive ants. Current
Opinion in Insect Science. Elsevier. https://doi.org/10.1016/j.cois.2019.03.011
chicago: Cremer, Sylvia. “Pathogens and Disease Defense of Invasive Ants.” Current
Opinion in Insect Science. Elsevier, 2019. https://doi.org/10.1016/j.cois.2019.03.011.
ieee: S. Cremer, “Pathogens and disease defense of invasive ants,” Current Opinion
in Insect Science, vol. 33. Elsevier, pp. 63–68, 2019.
ista: Cremer S. 2019. Pathogens and disease defense of invasive ants. Current Opinion
in Insect Science. 33, 63–68.
mla: Cremer, Sylvia. “Pathogens and Disease Defense of Invasive Ants.” Current
Opinion in Insect Science, vol. 33, Elsevier, 2019, pp. 63–68, doi:10.1016/j.cois.2019.03.011.
short: S. Cremer, Current Opinion in Insect Science 33 (2019) 63–68.
date_created: 2019-05-13T07:58:36Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2025-07-10T11:53:22Z
day: '01'
department:
- _id: SyCr
doi: 10.1016/j.cois.2019.03.011
external_id:
isi:
- '000477666000012'
intvolume: ' 33'
isi: 1
language:
- iso: eng
month: '06'
oa_version: None
page: 63-68
publication: Current Opinion in Insect Science
publication_identifier:
eissn:
- 2214-5753
issn:
- 2214-5745
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Pathogens and disease defense of invasive ants
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2019'
...
---
_id: '6418'
abstract:
- lang: eng
text: Males and females of Artemia franciscana, a crustacean commonly used in the
aquarium trade, are highly dimorphic. Sex is determined by a pair of ZW chromosomes,
but the nature and extent of differentiation of these chromosomes is unknown.
Here, we characterize the Z chromosome by detecting genomic regions that show
lower genomic coverage in female than in male samples, and regions that harbor
an excess of female-specific SNPs. We detect many Z-specific genes, which no longer
have homologs on the W, but also Z-linked genes that appear to have diverged very
recently from their existing W-linked homolog. We assess patterns of male and
female expression in two tissues with extensive morphological dimorphism, gonads,
and heads. In agreement with their morphology, sex-biased expression is common
in both tissues. Interestingly, the Z chromosome is not enriched for sex-biased
genes, and seems to in fact have a mechanism of dosage compensation that leads
to equal expression in males and in females. Both of these patterns are contrary
to most ZW systems studied so far, making A. franciscana an excellent model for
investigating the interplay between the evolution of sexual dimorphism and dosage
compensation, as well as Z chromosome evolution in general.
acknowledged_ssus:
- _id: ScienComp
article_processing_charge: No
author:
- first_name: Ann K
full_name: Huylmans, Ann K
id: 4C0A3874-F248-11E8-B48F-1D18A9856A87
last_name: Huylmans
orcid: 0000-0001-8871-4961
- first_name: Melissa A
full_name: Toups, Melissa A
id: 4E099E4E-F248-11E8-B48F-1D18A9856A87
last_name: Toups
orcid: 0000-0002-9752-7380
- first_name: Ariana
full_name: Macon, Ariana
id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
last_name: Macon
- first_name: William J
full_name: Gammerdinger, William J
id: 3A7E01BC-F248-11E8-B48F-1D18A9856A87
last_name: Gammerdinger
orcid: 0000-0001-9638-1220
- first_name: Beatriz
full_name: Vicoso, Beatriz
id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
last_name: Vicoso
orcid: 0000-0002-4579-8306
citation:
ama: Huylmans AK, Toups MA, Macon A, Gammerdinger WJ, Vicoso B. Sex-biased gene
expression and dosage compensation on the Artemia franciscana Z-chromosome. Genome
biology and evolution. 2019;11(4):1033-1044. doi:10.1093/gbe/evz053
apa: Huylmans, A. K., Toups, M. A., Macon, A., Gammerdinger, W. J., & Vicoso,
B. (2019). Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome. Genome Biology and Evolution. Oxford University Press. https://doi.org/10.1093/gbe/evz053
chicago: Huylmans, Ann K, Melissa A Toups, Ariana Macon, William J Gammerdinger,
and Beatriz Vicoso. “Sex-Biased Gene Expression and Dosage Compensation on the
Artemia Franciscana Z-Chromosome.” Genome Biology and Evolution. Oxford
University Press, 2019. https://doi.org/10.1093/gbe/evz053.
ieee: A. K. Huylmans, M. A. Toups, A. Macon, W. J. Gammerdinger, and B. Vicoso,
“Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome,” Genome biology and evolution, vol. 11, no. 4. Oxford University
Press, pp. 1033–1044, 2019.
ista: Huylmans AK, Toups MA, Macon A, Gammerdinger WJ, Vicoso B. 2019. Sex-biased
gene expression and dosage compensation on the Artemia franciscana Z-chromosome.
Genome biology and evolution. 11(4), 1033–1044.
mla: Huylmans, Ann K., et al. “Sex-Biased Gene Expression and Dosage Compensation
on the Artemia Franciscana Z-Chromosome.” Genome Biology and Evolution,
vol. 11, no. 4, Oxford University Press, 2019, pp. 1033–44, doi:10.1093/gbe/evz053.
short: A.K. Huylmans, M.A. Toups, A. Macon, W.J. Gammerdinger, B. Vicoso, Genome
Biology and Evolution 11 (2019) 1033–1044.
date_created: 2019-05-13T07:58:38Z
date_published: 2019-04-01T00:00:00Z
date_updated: 2025-04-14T07:41:21Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evz053
ec_funded: 1
external_id:
isi:
- '000476569800003'
file:
- access_level: open_access
checksum: 7d0ede297b6741f3dc89cd59017c7642
content_type: application/pdf
creator: dernst
date_created: 2019-05-14T08:29:38Z
date_updated: 2020-07-14T12:47:29Z
file_id: '6446'
file_name: 2019_GBE_Huylmans.pdf
file_size: 1256303
relation: main_file
file_date_updated: 2020-07-14T12:47:29Z
has_accepted_license: '1'
intvolume: ' 11'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 1033-1044
project:
- _id: 250BDE62-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715257'
name: Prevalence and Influence of Sexual Antagonism on Genome Evolution
publication: Genome biology and evolution
publication_identifier:
eissn:
- 1759-6653
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
record:
- id: '6060'
relation: popular_science
status: public
scopus_import: '1'
status: public
title: Sex-biased gene expression and dosage compensation on the Artemia franciscana
Z-chromosome
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2019'
...
---
OA_place: repository
OA_type: green
_id: '19987'
abstract:
- lang: eng
text: 'These lecture notes are based on Yang’s talk at the MATRIX program Geometric
R-Matrices: from Geometry to Probability, at the University of Melbourne, Dec.
18–22, 2017, and Zhao’s talk at Perimeter Institute for Theoretical Physics in
January 2018. We give an introductory survey of the results in Yang and Zhao (Quiver
varieties and elliptic quantum groups, 2017. arxiv1708.01418). We discuss a sheafified
elliptic quantum group associated to any symmetric Kac-Moody Lie algebra. The
sheafification is obtained by applying the equivariant elliptic cohomological
theory to the moduli space of representations of a preprojective algebra. By construction,
the elliptic quantum group naturally acts on the equivariant elliptic cohomology
of Nakajima quiver varieties. As an application, we obtain a relation between
the sheafified elliptic quantum group and the global affine Grassmannian over
an elliptic curve.'
acknowledgement: 'Y.Y. would like to thank the organizers of the MATRIX program Geometric
R-Matrices: from Geometry to Probability for their kind invitation, and many participants
of the program for useful discussions, including Vassily Gorbounov, Andrei Okounkov,
Allen Knutson, Hitoshi Konno, Paul Zinn-Justin. Proposition 1 and Sect. 3.3 are
new, for which we thank Hitoshi Konno for interesting discussions and communications.
These notes were written when both authors were visiting the Perimeter Institute
for Theoretical Physics (PI). We are grateful to PI for the hospitality.'
alternative_title:
- MATRIX Book Series
article_processing_charge: No
arxiv: 1
author:
- first_name: Yaping
full_name: Yang, Yaping
id: 360D8648-F248-11E8-B48F-1D18A9856A87
last_name: Yang
- first_name: Gufang
full_name: Zhao, Gufang
id: 2BC2AC5E-F248-11E8-B48F-1D18A9856A87
last_name: Zhao
citation:
ama: 'Yang Y, Zhao G. How to Sheafify an Elliptic Quantum Group. In: 2017 MATRIX
Annals. Vol 2. MXBS. Cham: Springer International Publishing; 2019:675-691.
doi:10.1007/978-3-030-04161-8_54'
apa: 'Yang, Y., & Zhao, G. (2019). How to Sheafify an Elliptic Quantum Group.
In 2017 MATRIX Annals (Vol. 2, pp. 675–691). Cham: Springer International
Publishing. https://doi.org/10.1007/978-3-030-04161-8_54'
chicago: 'Yang, Yaping, and Gufang Zhao. “How to Sheafify an Elliptic Quantum Group.”
In 2017 MATRIX Annals, 2:675–91. MXBS. Cham: Springer International Publishing,
2019. https://doi.org/10.1007/978-3-030-04161-8_54.'
ieee: 'Y. Yang and G. Zhao, “How to Sheafify an Elliptic Quantum Group,” in 2017
MATRIX Annals, vol. 2, Cham: Springer International Publishing, 2019, pp.
675–691.'
ista: 'Yang Y, Zhao G. 2019.How to Sheafify an Elliptic Quantum Group. In: 2017
MATRIX Annals. MATRIX Book Series, vol. 2, 675–691.'
mla: Yang, Yaping, and Gufang Zhao. “How to Sheafify an Elliptic Quantum Group.”
2017 MATRIX Annals, vol. 2, Springer International Publishing, 2019, pp.
675–91, doi:10.1007/978-3-030-04161-8_54.
short: Y. Yang, G. Zhao, in:, 2017 MATRIX Annals, Springer International Publishing,
Cham, 2019, pp. 675–691.
date_created: 2025-07-10T13:31:38Z
date_published: 2019-03-25T00:00:00Z
date_updated: 2025-09-23T11:59:52Z
day: '25'
department:
- _id: TaHa
doi: 10.1007/978-3-030-04161-8_54
external_id:
arxiv:
- '1803.06627'
intvolume: ' 2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1803.06627
month: '03'
oa: 1
oa_version: Preprint
page: 675-691
place: Cham
publication: 2017 MATRIX Annals
publication_identifier:
eisbn:
- '9783030041618'
eissn:
- 2523-305X
isbn:
- '9783030041601'
issn:
- 2523-3041
publication_status: published
publisher: Springer International Publishing
quality_controlled: '1'
series_title: MXBS
status: public
title: How to Sheafify an Elliptic Quantum Group
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2019'
...
---
OA_place: repository
OA_type: green
_id: '19988'
abstract:
- lang: eng
text: Quantitative studies of cell metabolism are often based on large chemical
reaction network models. A steady-state approach is suited to analyze phenomena
on the timescale of cell growth and circumvents the problem of incomplete experimental
knowledge on kinetic laws and parameters, but it should be supported by a correct
implementation of thermodynamic constraints. In this chapter, we review the latter
aspect, highlighting its computational challenges and physical insights. The simple
introduction of Gibbs inequalities avoids the presence of unfeasible loops allowing
for correct timescale analysis, but leads to possibly non-convex feasible flux
spaces whose exploration needs efficient algorithms. We briefly review the implementation
of thermodynamics through variational principles in constraint-based models of
metabolic networks.
article_processing_charge: No
arxiv: 1
author:
- first_name: A
full_name: De Martino, A
last_name: De Martino
- first_name: Daniele
full_name: De Martino, Daniele
id: 3FF5848A-F248-11E8-B48F-1D18A9856A87
last_name: De Martino
orcid: 0000-0002-5214-4706
- first_name: E
full_name: Marinari, E
last_name: Marinari
citation:
ama: 'De Martino A, De Martino D, Marinari E. The Essential Role of Thermodynamics
in Metabolic Network Modeling: Physical Insights and Computational Challenges.
In: Chemical Kinetics. World Scientific Publishing; 2019:455-471. doi:10.1142/9781786347015_0018'
apa: 'De Martino, A., De Martino, D., & Marinari, E. (2019). The Essential Role
of Thermodynamics in Metabolic Network Modeling: Physical Insights and Computational
Challenges. In Chemical Kinetics (pp. 455–471). World Scientific Publishing.
https://doi.org/10.1142/9781786347015_0018'
chicago: 'De Martino, A, Daniele De Martino, and E Marinari. “The Essential Role
of Thermodynamics in Metabolic Network Modeling: Physical Insights and Computational
Challenges.” In Chemical Kinetics, 455–71. World Scientific Publishing,
2019. https://doi.org/10.1142/9781786347015_0018.'
ieee: 'A. De Martino, D. De Martino, and E. Marinari, “The Essential Role of Thermodynamics
in Metabolic Network Modeling: Physical Insights and Computational Challenges,”
in Chemical Kinetics, World Scientific Publishing, 2019, pp. 455–471.'
ista: 'De Martino A, De Martino D, Marinari E. 2019.The Essential Role of Thermodynamics
in Metabolic Network Modeling: Physical Insights and Computational Challenges.
In: Chemical Kinetics. , 455–471.'
mla: 'De Martino, A., et al. “The Essential Role of Thermodynamics in Metabolic
Network Modeling: Physical Insights and Computational Challenges.” Chemical
Kinetics, World Scientific Publishing, 2019, pp. 455–71, doi:10.1142/9781786347015_0018.'
short: A. De Martino, D. De Martino, E. Marinari, in:, Chemical Kinetics, World
Scientific Publishing, 2019, pp. 455–471.
date_created: 2025-07-10T13:34:01Z
date_published: 2019-09-01T00:00:00Z
date_updated: 2025-09-23T11:53:34Z
day: '01'
department:
- _id: GaTk
doi: 10.1142/9781786347015_0018
external_id:
arxiv:
- '1902.07129'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.48550/arXiv.1902.07129
month: '09'
oa: 1
oa_version: Preprint
page: 455-471
publication: Chemical Kinetics
publication_identifier:
eisbn:
- '9781786347022'
isbn:
- '9781786347008'
publication_status: published
publisher: World Scientific Publishing
quality_controlled: '1'
status: public
title: 'The Essential Role of Thermodynamics in Metabolic Network Modeling: Physical
Insights and Computational Challenges'
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
OA_type: closed access
_id: '19989'
abstract:
- lang: ger
text: Neurone empfangen Eingangssignale, konvertieren diese in Aktionspotenziale
und generieren schließlich Ausgangssignale auf ihren Zielzellen. Dabei sind die
zu überwindenden räumlichen Distanzen oft groß. Daher ist entscheidend, dass elektrische
Signale in Nervenzellen schnell von einem zum anderen Ort geleitet werden können.
Diese wichtige Aufgabe erfüllt das Axon, der „Ausgangsfortsatz“ der Nervenzelle.
Für die schnelle Leitung des Aktionspotenzials sind sowohl die passiven Eigenschaften
des axonalen Kabels als auch die aktiven Eigenschaften der Zellmembran von entscheidender
Bedeutung. Die Evolution bedient sich zweier Tricks, um die Leitungsgeschwindigkeit
des Aktionspotenzials zu maximieren. Der eine Trick ist die Zunahme des Axondurchmessers.
Der andere Trick ist die Ausbildung von Markscheiden. Dies führt bei nahezu gleichem
Platzbedarf zu einer Zunahme der Leistungsgeschwindigkeit um fast zwei Größenordnungen.
Die Aktionspotenzialleitung an myelinisierten Axonen erfolgt „saltatorisch“.
article_processing_charge: No
author:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Jonas PM. Aktionspotenzial: Fortleitung im Axon. In: Physiologie des Menschen.
32nd ed. Springer-Lehrbuch. Berlin, Heidelberg: Springer Nature; 2019:72-82. doi:10.1007/978-3-662-56468-4_7'
apa: 'Jonas, P. M. (2019). Aktionspotenzial: Fortleitung im Axon. In Physiologie
des Menschen (32nd ed., pp. 72–82). Berlin, Heidelberg: Springer Nature. https://doi.org/10.1007/978-3-662-56468-4_7'
chicago: 'Jonas, Peter M. “Aktionspotenzial: Fortleitung im Axon.” In Physiologie
des Menschen, 32nd ed., 72–82. Springer-Lehrbuch. Berlin, Heidelberg: Springer
Nature, 2019. https://doi.org/10.1007/978-3-662-56468-4_7.'
ieee: 'P. M. Jonas, “Aktionspotenzial: Fortleitung im Axon,” in Physiologie des
Menschen, 32nd ed., Berlin, Heidelberg: Springer Nature, 2019, pp. 72–82.'
ista: 'Jonas PM. 2019.Aktionspotenzial: Fortleitung im Axon. In: Physiologie des
Menschen. , 72–82.'
mla: 'Jonas, Peter M. “Aktionspotenzial: Fortleitung im Axon.” Physiologie des
Menschen, 32nd ed., Springer Nature, 2019, pp. 72–82, doi:10.1007/978-3-662-56468-4_7.'
short: P.M. Jonas, in:, Physiologie des Menschen, 32nd ed., Springer Nature, Berlin,
Heidelberg, 2019, pp. 72–82.
corr_author: '1'
date_created: 2025-07-10T13:36:36Z
date_published: 2019-04-02T00:00:00Z
date_updated: 2025-09-23T11:44:57Z
day: '02'
department:
- _id: PeJo
doi: 10.1007/978-3-662-56468-4_7
edition: '32'
language:
- iso: ger
month: '04'
oa_version: None
page: 72-82
place: Berlin, Heidelberg
publication: Physiologie des Menschen
publication_identifier:
eisbn:
- '9783662564684'
eissn:
- 2512-5214
isbn:
- '9783662564677'
issn:
- 0937-7433
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
series_title: Springer-Lehrbuch
status: public
title: 'Aktionspotenzial: Fortleitung im Axon'
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
OA_place: publisher
OA_type: hybrid
_id: '10190'
abstract:
- lang: eng
text: 'The verification of concurrent programs remains an open challenge, as thread
interaction has to be accounted for, which leads to state-space explosion. Stateless
model checking battles this problem by exploring traces rather than states of
the program. As there are exponentially many traces, dynamic partial-order reduction
(DPOR) techniques are used to partition the trace space into equivalence classes,
and explore a few representatives from each class. The standard equivalence that
underlies most DPOR techniques is the happens-before equivalence, however recent
works have spawned a vivid interest towards coarser equivalences. The efficiency
of such approaches is a product of two parameters: (i) the size of the partitioning
induced by the equivalence, and (ii) the time spent by the exploration algorithm
in each class of the partitioning. In this work, we present a new equivalence,
called value-happens-before and show that it has two appealing features. First,
value-happens-before is always at least as coarse as the happens-before equivalence,
and can be even exponentially coarser. Second, the value-happens-before partitioning
is efficiently explorable when the number of threads is bounded. We present an
algorithm called value-centric DPOR (VCDPOR), which explores the underlying partitioning
using polynomial time per class. Finally, we perform an experimental evaluation
of VCDPOR on various benchmarks, and compare it against other state-of-the-art
approaches. Our results show that value-happens-before typically induces a significant
reduction in the size of the underlying partitioning, which leads to a considerable
reduction in the running time for exploring the whole partitioning.'
acknowledgement: "The authors would also like to thank anonymous referees for their
valuable comments and helpful suggestions. This work is supported by the Austrian
Science Fund (FWF) NFN grants S11407-N23 (RiSE/SHiNE) and S11402-N23 (RiSE/SHiNE),
by the Vienna Science and Technology Fund (WWTF) Project ICT15-003, and by the Austrian
Science Fund (FWF) Schrodinger grant J-4220.\r\n"
article_number: '124'
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
- first_name: Viktor
full_name: Toman, Viktor
id: 3AF3DA7C-F248-11E8-B48F-1D18A9856A87
last_name: Toman
orcid: 0000-0001-9036-063X
citation:
ama: 'Chatterjee K, Pavlogiannis A, Toman V. Value-centric dynamic partial order
reduction. In: Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications. Vol 3. ACM; 2019. doi:10.1145/3360550'
apa: 'Chatterjee, K., Pavlogiannis, A., & Toman, V. (2019). Value-centric dynamic
partial order reduction. In Proceedings of the 34th ACM International Conference
on Object-Oriented Programming, Systems, Languages, and Applications (Vol.
3). Athens, Greece: ACM. https://doi.org/10.1145/3360550'
chicago: Chatterjee, Krishnendu, Andreas Pavlogiannis, and Viktor Toman. “Value-Centric
Dynamic Partial Order Reduction.” In Proceedings of the 34th ACM International
Conference on Object-Oriented Programming, Systems, Languages, and Applications,
Vol. 3. ACM, 2019. https://doi.org/10.1145/3360550.
ieee: K. Chatterjee, A. Pavlogiannis, and V. Toman, “Value-centric dynamic partial
order reduction,” in Proceedings of the 34th ACM International Conference on
Object-Oriented Programming, Systems, Languages, and Applications, Athens,
Greece, 2019, vol. 3.
ista: 'Chatterjee K, Pavlogiannis A, Toman V. 2019. Value-centric dynamic partial
order reduction. Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications. OOPSLA: Object-oriented Programming,
Systems, Languages and Applications vol. 3, 124.'
mla: Chatterjee, Krishnendu, et al. “Value-Centric Dynamic Partial Order Reduction.”
Proceedings of the 34th ACM International Conference on Object-Oriented Programming,
Systems, Languages, and Applications, vol. 3, 124, ACM, 2019, doi:10.1145/3360550.
short: K. Chatterjee, A. Pavlogiannis, V. Toman, in:, Proceedings of the 34th ACM
International Conference on Object-Oriented Programming, Systems, Languages, and
Applications, ACM, 2019.
conference:
end_date: 2019-10-25
location: Athens, Greece
name: 'OOPSLA: Object-oriented Programming, Systems, Languages and Applications'
start_date: 2019-10-23
corr_author: '1'
date_created: 2021-10-27T14:57:06Z
date_published: 2019-10-10T00:00:00Z
date_updated: 2026-04-08T07:00:31Z
day: '10'
ddc:
- '000'
department:
- _id: GradSch
- _id: KrCh
doi: 10.1145/3360550
external_id:
arxiv:
- '1909.00989'
file:
- access_level: open_access
checksum: 2149979c46964c4d117af06ccb6c0834
content_type: application/pdf
creator: cchlebak
date_created: 2021-11-12T11:41:56Z
date_updated: 2021-11-12T11:41:56Z
file_id: '10278'
file_name: 2019_ACM_Chatterjee.pdf
file_size: 570829
relation: main_file
success: 1
file_date_updated: 2021-11-12T11:41:56Z
has_accepted_license: '1'
intvolume: ' 3'
keyword:
- safety
- risk
- reliability and quality
- software
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
grant_number: ICT15-003
name: Efficient Algorithms for Computer Aided Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11402-N23
name: Moderne Concurrency Paradigms
publication: Proceedings of the 34th ACM International Conference on Object-Oriented
Programming, Systems, Languages, and Applications
publication_identifier:
eissn:
- 2475-1421
publication_status: published
publisher: ACM
quality_controlled: '1'
related_material:
record:
- id: '10199'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: Value-centric dynamic partial order reduction
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2019'
...
---
_id: '105'
abstract:
- lang: eng
text: 'Clinical Utility Gene Card. 1. Name of Disease (Synonyms): Pontocerebellar
hypoplasia type 9 (PCH9) and spastic paraplegia-63 (SPG63). 2. OMIM# of the Disease:
615809 and 615686. 3. Name of the Analysed Genes or DNA/Chromosome Segments: AMPD2
at 1p13.3. 4. OMIM# of the Gene(s): 102771.'
acknowledgement: 'This work was supported by EuroGentest2 (Unit 2: “Genetic testing
as part of health care”), a Coordination Action under FP7 (Grant Agreement Number
261469) and the European Society of Human Genetics. We acknowledge the participation
of the patients and their families in these studies, as well as the generous financial
support of the Lefroy and Handbury families. APLM was supported by an Australian
Postgraduate Award. PJL is supported by an NHMRC Career Development Fellowship (GNT1032364).
RJL is supported by a Melbourne Children’s Clinician Scientist Fellowship.'
article_processing_charge: No
article_type: original
author:
- first_name: Ashley
full_name: Marsh, Ashley
last_name: Marsh
- first_name: Gaia
full_name: Novarino, Gaia
id: 3E57A680-F248-11E8-B48F-1D18A9856A87
last_name: Novarino
orcid: 0000-0002-7673-7178
- first_name: Paul
full_name: Lockhart, Paul
last_name: Lockhart
- first_name: Richard
full_name: Leventer, Richard
last_name: Leventer
citation:
ama: Marsh A, Novarino G, Lockhart P, Leventer R. CUGC for pontocerebellar hypoplasia
type 9 and spastic paraplegia-63. European Journal of Human Genetics. 2019;27:161-166.
doi:10.1038/s41431-018-0231-2
apa: Marsh, A., Novarino, G., Lockhart, P., & Leventer, R. (2019). CUGC for
pontocerebellar hypoplasia type 9 and spastic paraplegia-63. European Journal
of Human Genetics. Springer Nature. https://doi.org/10.1038/s41431-018-0231-2
chicago: Marsh, Ashley, Gaia Novarino, Paul Lockhart, and Richard Leventer. “CUGC
for Pontocerebellar Hypoplasia Type 9 and Spastic Paraplegia-63.” European
Journal of Human Genetics. Springer Nature, 2019. https://doi.org/10.1038/s41431-018-0231-2.
ieee: A. Marsh, G. Novarino, P. Lockhart, and R. Leventer, “CUGC for pontocerebellar
hypoplasia type 9 and spastic paraplegia-63,” European Journal of Human Genetics,
vol. 27. Springer Nature, pp. 161–166, 2019.
ista: Marsh A, Novarino G, Lockhart P, Leventer R. 2019. CUGC for pontocerebellar
hypoplasia type 9 and spastic paraplegia-63. European Journal of Human Genetics.
27, 161–166.
mla: Marsh, Ashley, et al. “CUGC for Pontocerebellar Hypoplasia Type 9 and Spastic
Paraplegia-63.” European Journal of Human Genetics, vol. 27, Springer Nature,
2019, pp. 161–66, doi:10.1038/s41431-018-0231-2.
short: A. Marsh, G. Novarino, P. Lockhart, R. Leventer, European Journal of Human
Genetics 27 (2019) 161–166.
date_created: 2018-12-11T11:44:39Z
date_published: 2019-01-01T00:00:00Z
date_updated: 2026-06-18T08:42:55Z
day: '01'
ddc:
- '570'
department:
- _id: GaNo
doi: 10.1038/s41431-018-0231-2
external_id:
isi:
- '000454111500019'
pmid:
- '30089829'
intvolume: ' 27'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41431-018-0231-2
month: '01'
oa: 1
oa_version: Published Version
page: 161-166
pmid: 1
publication: European Journal of Human Genetics
publication_status: published
publisher: Springer Nature
publist_id: '7949'
quality_controlled: '1'
scopus_import: '1'
status: public
title: CUGC for pontocerebellar hypoplasia type 9 and spastic paraplegia-63
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2019'
...
---
_id: '7576'
abstract:
- lang: eng
text: We present the results of a friendly competition for formal verification of
continuous and hybrid systems with nonlinear continuous dynamics. The friendly
competition took place as part of the workshop Applied Verification for Continuous
and Hybrid Systems (ARCH) in 2019. In this year, 6 tools Ariadne, CORA, DynIbex,
Flow*, Isabelle/HOL, and JuliaReach (in alphabetic order) participated. They are
applied to solve reachability analysis problems on four benchmark problems, one
of them with hybrid dynamics. We do not rank the tools based on the results, but
show the current status and discover the potential advantages of different tools.
article_processing_charge: No
author:
- first_name: Fabian
full_name: Immler, Fabian
last_name: Immler
- first_name: Matthias
full_name: Althoff, Matthias
last_name: Althoff
- first_name: Luis
full_name: Benet, Luis
last_name: Benet
- first_name: Alexandre
full_name: Chapoutot, Alexandre
last_name: Chapoutot
- first_name: Xin
full_name: Chen, Xin
last_name: Chen
- first_name: Marcelo
full_name: Forets, Marcelo
last_name: Forets
- first_name: Luca
full_name: Geretti, Luca
last_name: Geretti
- first_name: Niklas
full_name: Kochdumper, Niklas
last_name: Kochdumper
- first_name: David P.
full_name: Sanders, David P.
last_name: Sanders
- first_name: Christian
full_name: Schilling, Christian
id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
last_name: Schilling
orcid: 0000-0003-3658-1065
citation:
ama: 'Immler F, Althoff M, Benet L, et al. ARCH-COMP19 Category Report: Continuous
and hybrid systems with nonlinear dynamics. In: EPiC Series in Computing.
Vol 61. EasyChair; 2019:41-61. doi:10.29007/m75b'
apa: 'Immler, F., Althoff, M., Benet, L., Chapoutot, A., Chen, X., Forets, M., …
Schilling, C. (2019). ARCH-COMP19 Category Report: Continuous and hybrid systems
with nonlinear dynamics. In EPiC Series in Computing (Vol. 61, pp. 41–61).
Montreal, Canada: EasyChair. https://doi.org/10.29007/m75b'
chicago: 'Immler, Fabian, Matthias Althoff, Luis Benet, Alexandre Chapoutot, Xin
Chen, Marcelo Forets, Luca Geretti, Niklas Kochdumper, David P. Sanders, and Christian
Schilling. “ARCH-COMP19 Category Report: Continuous and Hybrid Systems with Nonlinear
Dynamics.” In EPiC Series in Computing, 61:41–61. EasyChair, 2019. https://doi.org/10.29007/m75b.'
ieee: 'F. Immler et al., “ARCH-COMP19 Category Report: Continuous and hybrid
systems with nonlinear dynamics,” in EPiC Series in Computing, Montreal,
Canada, 2019, vol. 61, pp. 41–61.'
ista: 'Immler F, Althoff M, Benet L, Chapoutot A, Chen X, Forets M, Geretti L, Kochdumper
N, Sanders DP, Schilling C. 2019. ARCH-COMP19 Category Report: Continuous and
hybrid systems with nonlinear dynamics. EPiC Series in Computing. ARCH: International
Workshop on Applied Verification on Continuous and Hybrid Systems vol. 61, 41–61.'
mla: 'Immler, Fabian, et al. “ARCH-COMP19 Category Report: Continuous and Hybrid
Systems with Nonlinear Dynamics.” EPiC Series in Computing, vol. 61, EasyChair,
2019, pp. 41–61, doi:10.29007/m75b.'
short: F. Immler, M. Althoff, L. Benet, A. Chapoutot, X. Chen, M. Forets, L. Geretti,
N. Kochdumper, D.P. Sanders, C. Schilling, in:, EPiC Series in Computing, EasyChair,
2019, pp. 41–61.
conference:
end_date: 2019-04-15
location: Montreal, Canada
name: 'ARCH: International Workshop on Applied Verification on Continuous and Hybrid
Systems'
start_date: 2019-04-15
corr_author: '1'
date_created: 2020-03-08T23:00:49Z
date_published: 2019-05-25T00:00:00Z
date_updated: 2026-04-03T09:51:13Z
day: '25'
ddc:
- '000'
department:
- _id: ToHe
doi: 10.29007/m75b
file:
- access_level: open_access
checksum: 9138977a06fcd6a95976eb4bca875f0c
content_type: application/pdf
creator: dernst
date_created: 2020-03-24T07:36:36Z
date_updated: 2020-07-14T12:48:00Z
file_id: '7617'
file_name: 2019_ARCH19_Immler.pdf
file_size: 1934830
relation: main_file
file_date_updated: 2020-07-14T12:48:00Z
has_accepted_license: '1'
intvolume: ' 61'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 41-61
publication: EPiC Series in Computing
publication_identifier:
eissn:
- 2398-7340
publication_status: published
publisher: EasyChair
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'ARCH-COMP19 Category Report: Continuous and hybrid systems with nonlinear
dynamics'
type: conference
user_id: ba8df636-2132-11f1-aed0-ed93e2281fdd
volume: 61
year: '2019'
...
---
_id: '7606'
abstract:
- lang: eng
text: We derive a tight lower bound on equivocation (conditional entropy), or equivalently
a tight upper bound on mutual information between a signal variable and channel
outputs. The bound is in terms of the joint distribution of the signals and maximum
a posteriori decodes (most probable signals given channel output). As part of
our derivation, we describe the key properties of the distribution of signals,
channel outputs and decodes, that minimizes equivocation and maximizes mutual
information. This work addresses a problem in data analysis, where mutual information
between signals and decodes is sometimes used to lower bound the mutual information
between signals and channel outputs. Our result provides a corresponding upper
bound.
article_number: '8989292'
article_processing_charge: No
arxiv: 1
author:
- first_name: Michal
full_name: Hledik, Michal
id: 4171253A-F248-11E8-B48F-1D18A9856A87
last_name: Hledik
- first_name: Thomas R
full_name: Sokolowski, Thomas R
id: 3E999752-F248-11E8-B48F-1D18A9856A87
last_name: Sokolowski
orcid: 0000-0002-1287-3779
- first_name: Gašper
full_name: Tkačik, Gašper
id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
last_name: Tkačik
orcid: 0000-0002-6699-1455
citation:
ama: 'Hledik M, Sokolowski TR, Tkačik G. A tight upper bound on mutual information.
In: IEEE Information Theory Workshop, ITW 2019. IEEE; 2019. doi:10.1109/ITW44776.2019.8989292'
apa: 'Hledik, M., Sokolowski, T. R., & Tkačik, G. (2019). A tight upper bound
on mutual information. In IEEE Information Theory Workshop, ITW 2019. Visby,
Sweden: IEEE. https://doi.org/10.1109/ITW44776.2019.8989292'
chicago: Hledik, Michal, Thomas R Sokolowski, and Gašper Tkačik. “A Tight Upper
Bound on Mutual Information.” In IEEE Information Theory Workshop, ITW 2019.
IEEE, 2019. https://doi.org/10.1109/ITW44776.2019.8989292.
ieee: M. Hledik, T. R. Sokolowski, and G. Tkačik, “A tight upper bound on mutual
information,” in IEEE Information Theory Workshop, ITW 2019, Visby, Sweden,
2019.
ista: Hledik M, Sokolowski TR, Tkačik G. 2019. A tight upper bound on mutual information.
IEEE Information Theory Workshop, ITW 2019. Information Theory Workshop, 8989292.
mla: Hledik, Michal, et al. “A Tight Upper Bound on Mutual Information.” IEEE
Information Theory Workshop, ITW 2019, 8989292, IEEE, 2019, doi:10.1109/ITW44776.2019.8989292.
short: M. Hledik, T.R. Sokolowski, G. Tkačik, in:, IEEE Information Theory Workshop,
ITW 2019, IEEE, 2019.
conference:
end_date: 2019-08-28
location: Visby, Sweden
name: Information Theory Workshop
start_date: 2019-08-25
date_created: 2020-03-22T23:00:47Z
date_published: 2019-08-01T00:00:00Z
date_updated: 2026-04-07T12:59:24Z
day: '01'
department:
- _id: GaTk
doi: 10.1109/ITW44776.2019.8989292
ec_funded: 1
external_id:
arxiv:
- '1812.01475'
isi:
- '000540384500015'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1812.01475
month: '08'
oa: 1
oa_version: Preprint
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '665385'
name: International IST Doctoral Program
publication: IEEE Information Theory Workshop, ITW 2019
publication_identifier:
isbn:
- '9781538669006'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
record:
- id: '15020'
relation: dissertation_contains
status: public
scopus_import: '1'
status: public
title: A tight upper bound on mutual information
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '7639'
abstract:
- lang: eng
text: Deep neural networks (DNNs) have become increasingly important due to their
excellent empirical performance on a wide range of problems. However, regularization
is generally achieved by indirect means, largely due to the complex set of functions
defined by a network and the difficulty in measuring function complexity. There
exists no method in the literature for additive regularization based on a norm
of the function, as is classically considered in statistical learning theory.
In this work, we study the tractability of function norms for deep neural networks
with ReLU activations. We provide, to the best of our knowledge, the first proof
in the literature of the NP-hardness of computing function norms of DNNs of 3
or more layers. We also highlight a fundamental difference between shallow and
deep networks. In the light on these results, we propose a new regularization
strategy based on approximate function norms, and show its efficiency on a segmentation
task with a DNN.
article_number: 748-752
article_processing_charge: No
author:
- first_name: Amal
full_name: Rannen-Triki, Amal
last_name: Rannen-Triki
- first_name: Maxim
full_name: Berman, Maxim
last_name: Berman
- first_name: Vladimir
full_name: Kolmogorov, Vladimir
id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
last_name: Kolmogorov
- first_name: Matthew B.
full_name: Blaschko, Matthew B.
last_name: Blaschko
citation:
ama: 'Rannen-Triki A, Berman M, Kolmogorov V, Blaschko MB. Function norms for neural
networks. In: Proceedings of the 2019 International Conference on Computer
Vision Workshop. IEEE; 2019. doi:10.1109/ICCVW.2019.00097'
apa: 'Rannen-Triki, A., Berman, M., Kolmogorov, V., & Blaschko, M. B. (2019).
Function norms for neural networks. In Proceedings of the 2019 International
Conference on Computer Vision Workshop. Seoul, South Korea: IEEE. https://doi.org/10.1109/ICCVW.2019.00097'
chicago: Rannen-Triki, Amal, Maxim Berman, Vladimir Kolmogorov, and Matthew B. Blaschko.
“Function Norms for Neural Networks.” In Proceedings of the 2019 International
Conference on Computer Vision Workshop. IEEE, 2019. https://doi.org/10.1109/ICCVW.2019.00097.
ieee: A. Rannen-Triki, M. Berman, V. Kolmogorov, and M. B. Blaschko, “Function norms
for neural networks,” in Proceedings of the 2019 International Conference on
Computer Vision Workshop, Seoul, South Korea, 2019.
ista: 'Rannen-Triki A, Berman M, Kolmogorov V, Blaschko MB. 2019. Function norms
for neural networks. Proceedings of the 2019 International Conference on Computer
Vision Workshop. ICCVW: International Conference on Computer Vision Workshop,
748–752.'
mla: Rannen-Triki, Amal, et al. “Function Norms for Neural Networks.” Proceedings
of the 2019 International Conference on Computer Vision Workshop, 748–752,
IEEE, 2019, doi:10.1109/ICCVW.2019.00097.
short: A. Rannen-Triki, M. Berman, V. Kolmogorov, M.B. Blaschko, in:, Proceedings
of the 2019 International Conference on Computer Vision Workshop, IEEE, 2019.
conference:
end_date: 2019-10-28
location: Seoul, South Korea
name: 'ICCVW: International Conference on Computer Vision Workshop'
start_date: 2019-10-27
date_created: 2020-04-05T22:00:50Z
date_published: 2019-10-01T00:00:00Z
date_updated: 2023-09-08T11:19:12Z
day: '01'
department:
- _id: VlKo
doi: 10.1109/ICCVW.2019.00097
external_id:
isi:
- '000554591600090'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
publication: Proceedings of the 2019 International Conference on Computer Vision Workshop
publication_identifier:
isbn:
- '9781728150239'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Function norms for neural networks
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '7640'
abstract:
- lang: eng
text: We propose a new model for detecting visual relationships, such as "person
riding motorcycle" or "bottle on table". This task is an important step towards
comprehensive structured mage understanding, going beyond detecting individual
objects. Our main novelty is a Box Attention mechanism that allows to model pairwise
interactions between objects using standard object detection pipelines. The resulting
model is conceptually clean, expressive and relies on well-justified training
and prediction procedures. Moreover, unlike previously proposed approaches, our
model does not introduce any additional complex components or hyperparameters
on top of those already required by the underlying detection model. We conduct
an experimental evaluation on two datasets, V-COCO and Open Images, demonstrating
strong quantitative and qualitative results.
article_number: 1749-1753
article_processing_charge: No
arxiv: 1
author:
- first_name: Alexander
full_name: Kolesnikov, Alexander
id: 2D157DB6-F248-11E8-B48F-1D18A9856A87
last_name: Kolesnikov
- first_name: Alina
full_name: Kuznetsova, Alina
last_name: Kuznetsova
- first_name: Christoph
full_name: Lampert, Christoph
id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
last_name: Lampert
orcid: 0000-0001-8622-7887
- first_name: Vittorio
full_name: Ferrari, Vittorio
last_name: Ferrari
citation:
ama: 'Kolesnikov A, Kuznetsova A, Lampert C, Ferrari V. Detecting visual relationships
using box attention. In: Proceedings of the 2019 International Conference on
Computer Vision Workshop. IEEE; 2019. doi:10.1109/ICCVW.2019.00217'
apa: 'Kolesnikov, A., Kuznetsova, A., Lampert, C., & Ferrari, V. (2019). Detecting
visual relationships using box attention. In Proceedings of the 2019 International
Conference on Computer Vision Workshop. Seoul, South Korea: IEEE. https://doi.org/10.1109/ICCVW.2019.00217'
chicago: Kolesnikov, Alexander, Alina Kuznetsova, Christoph Lampert, and Vittorio
Ferrari. “Detecting Visual Relationships Using Box Attention.” In Proceedings
of the 2019 International Conference on Computer Vision Workshop. IEEE, 2019.
https://doi.org/10.1109/ICCVW.2019.00217.
ieee: A. Kolesnikov, A. Kuznetsova, C. Lampert, and V. Ferrari, “Detecting visual
relationships using box attention,” in Proceedings of the 2019 International
Conference on Computer Vision Workshop, Seoul, South Korea, 2019.
ista: 'Kolesnikov A, Kuznetsova A, Lampert C, Ferrari V. 2019. Detecting visual
relationships using box attention. Proceedings of the 2019 International Conference
on Computer Vision Workshop. ICCVW: International Conference on Computer Vision
Workshop, 1749–1753.'
mla: Kolesnikov, Alexander, et al. “Detecting Visual Relationships Using Box Attention.”
Proceedings of the 2019 International Conference on Computer Vision Workshop,
1749–1753, IEEE, 2019, doi:10.1109/ICCVW.2019.00217.
short: A. Kolesnikov, A. Kuznetsova, C. Lampert, V. Ferrari, in:, Proceedings of
the 2019 International Conference on Computer Vision Workshop, IEEE, 2019.
conference:
end_date: 2019-10-28
location: Seoul, South Korea
name: 'ICCVW: International Conference on Computer Vision Workshop'
start_date: 2019-10-27
date_created: 2020-04-05T22:00:51Z
date_published: 2019-10-01T00:00:00Z
date_updated: 2025-04-15T07:10:23Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/ICCVW.2019.00217
ec_funded: 1
external_id:
arxiv:
- '1807.02136'
isi:
- '000554591601098'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1807.02136
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 2532554C-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '308036'
name: Lifelong Learning of Visual Scene Understanding
publication: Proceedings of the 2019 International Conference on Computer Vision Workshop
publication_identifier:
isbn:
- '9781728150239'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Detecting visual relationships using box attention
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '7950'
abstract:
- lang: eng
text: "The input to the token swapping problem is a graph with vertices v1, v2,
. . . , vn, and n tokens with labels 1,2, . . . , n, one on each vertex. The
goal is to get token i to vertex vi for all i= 1, . . . , n using a minimum number
of swaps, where a swap exchanges the tokens on the endpoints of an edge.Token
swapping on a tree, also known as “sorting with a transposition tree,” is not
known to be in P nor NP-complete. We present some partial results:\r\n1. An
optimum swap sequence may need to perform a swap on a leaf vertex that has the
correct token (a “happy leaf”), disproving a conjecture of Vaughan.\r\n2. Any
algorithm that fixes happy leaves—as all known approximation algorithms for the
problem do—has approximation factor at least 4/3. Furthermore, the two best-known
2-approximation algorithms have approximation factor exactly 2.\r\n3. A generalized
problem—weighted coloured token swapping—is NP-complete on trees, but solvable
in polynomial time on paths and stars. In this version, tokens and vertices
\ have colours, and colours have weights. The goal is to get every
token to a vertex of the same colour, and the cost of a swap is the sum of the
weights of the two tokens involved."
article_number: '1903.06981'
article_processing_charge: No
arxiv: 1
author:
- first_name: Ahmad
full_name: Biniaz, Ahmad
last_name: Biniaz
- first_name: Kshitij
full_name: Jain, Kshitij
last_name: Jain
- first_name: Anna
full_name: Lubiw, Anna
last_name: Lubiw
- first_name: Zuzana
full_name: Masárová, Zuzana
id: 45CFE238-F248-11E8-B48F-1D18A9856A87
last_name: Masárová
orcid: 0000-0002-6660-1322
- first_name: Tillmann
full_name: Miltzow, Tillmann
last_name: Miltzow
- first_name: Debajyoti
full_name: Mondal, Debajyoti
last_name: Mondal
- first_name: Anurag Murty
full_name: Naredla, Anurag Murty
last_name: Naredla
- first_name: Josef
full_name: Tkadlec, Josef
id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
last_name: Tkadlec
orcid: 0000-0002-1097-9684
- first_name: Alexi
full_name: Turcotte, Alexi
last_name: Turcotte
citation:
ama: Biniaz A, Jain K, Lubiw A, et al. Token swapping on trees. arXiv. doi:10.48550/arXiv.1903.06981
apa: Biniaz, A., Jain, K., Lubiw, A., Masárová, Z., Miltzow, T., Mondal, D., … Turcotte,
A. (n.d.). Token swapping on trees. arXiv. https://doi.org/10.48550/arXiv.1903.06981
chicago: Biniaz, Ahmad, Kshitij Jain, Anna Lubiw, Zuzana Masárová, Tillmann Miltzow,
Debajyoti Mondal, Anurag Murty Naredla, Josef Tkadlec, and Alexi Turcotte. “Token
Swapping on Trees.” ArXiv, n.d. https://doi.org/10.48550/arXiv.1903.06981.
ieee: A. Biniaz et al., “Token swapping on trees,” arXiv. .
ista: Biniaz A, Jain K, Lubiw A, Masárová Z, Miltzow T, Mondal D, Naredla AM, Tkadlec
J, Turcotte A. Token swapping on trees. arXiv, 1903.06981.
mla: Biniaz, Ahmad, et al. “Token Swapping on Trees.” ArXiv, 1903.06981,
doi:10.48550/arXiv.1903.06981.
short: A. Biniaz, K. Jain, A. Lubiw, Z. Masárová, T. Miltzow, D. Mondal, A.M. Naredla,
J. Tkadlec, A. Turcotte, ArXiv (n.d.).
date_created: 2020-06-08T12:25:25Z
date_published: 2019-03-16T00:00:00Z
date_updated: 2026-04-08T07:23:00Z
day: '16'
department:
- _id: HeEd
- _id: UlWa
- _id: KrCh
doi: 10.48550/arXiv.1903.06981
external_id:
arxiv:
- '1903.06981'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1903.06981
month: '03'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: draft
related_material:
record:
- id: '12833'
relation: later_version
status: public
- id: '7944'
relation: dissertation_contains
status: public
status: public
title: Token swapping on trees
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '8'
abstract:
- lang: eng
text: Despite their different origins, Drosophila glia and hemocytes are related
cell populations that provide an immune function. Drosophila hemocytes patrol
the body cavity and act as macrophages outside the nervous system whereas glia
originate from the neuroepithelium and provide the scavenger population of the
nervous system. Drosophila glia are hence the functional orthologs of vertebrate
microglia, even though the latter are cells of immune origin that subsequently
move into the brain during development. Interestingly, the Drosophila immune cells
within (glia) and outside the nervous system (hemocytes) require the same transcription
factor Glide/Gcm for their development. This raises the issue of how do glia specifically
differentiate in the nervous system and hemocytes in the procephalic mesoderm.
The Repo homeodomain transcription factor and pan-glial direct target of Glide/Gcm
is known to ensure glial terminal differentiation. Here we show that Repo also
takes center stage in the process that discriminates between glia and hemocytes.
First, Repo expression is repressed in the hemocyte anlagen by mesoderm-specific
factors. Second, Repo ectopic activation in the procephalic mesoderm is sufficient
to repress the expression of hemocyte-specific genes. Third, the lack of Repo
triggers the expression of hemocyte markers in glia. Thus, a complex network of
tissue-specific cues biases the potential of Glide/Gcm. These data allow us to
revise the concept of fate determinants and help us understand the bases of cell
specification. Both sexes were analyzed.SIGNIFICANCE STATEMENTDistinct cell types
often require the same pioneer transcription factor, raising the issue of how
does one factor trigger different fates. In Drosophila, glia and hemocytes provide
a scavenger activity within and outside the nervous system, respectively. While
they both require the Glide/Gcm transcription factor, glia originate from the
ectoderm, hemocytes from the mesoderm. Here we show that tissue-specific factors
inhibit the gliogenic potential of Glide/Gcm in the mesoderm by repressing the
expression of the homeodomain protein Repo, a major glial-specific target of Glide/Gcm.
Repo expression in turn inhibits the expression of hemocyte-specific genes in
the nervous system. These cell-specific networks secure the establishment of the
glial fate only in the nervous system and allow cell diversification.
acknowledgement: This work was supported by INSERM, CNRS, UDS, Ligue Régionale contre
le Cancer, Hôpital de Strasbourg, Association pour la Recherche sur le Cancer (ARC)
and Agence Nationale de la Recherche (ANR) grants. P.B.C. was funded by the ANR
and by the ARSEP (Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques),
and G.T. by governmental and ARC fellowships. This work was also supported by grants
from the Ataxia UK (2491) and the NC3R (NC/L000199/1) awarded to M.F. The Institut
de Génétique et de Biologie Moléculaire et Cellulaire was also supported by a French
state fund through the ANR labex. D.E.S. was funded by Marie Curie Grant CIG 334077/IRTIM.
We thank B. Altenhein, K. Brückner, M. Crozatier, L. Waltzer, M. Logan, E. Kurant,
R. Reuter, E. Kurucz, J.L Dimarcq, J. Hoffmann, C. Goodman, the DHSB, and the BDSC
for reagents and flies. We also thank all of the laboratory members for comments
on the manuscript; C. Diebold, C. Delaporte, M. Pezze, the fly, and imaging and
antibody facilities for technical assistance; and D. Dembele for help with statistics.
In addition, we thank Alison Brewer for help with Luciferase assays.
article_processing_charge: No
article_type: original
author:
- first_name: Guillaume
full_name: Trébuchet, Guillaume
last_name: Trébuchet
- first_name: Pierre B
full_name: Cattenoz, Pierre B
last_name: Cattenoz
- first_name: János
full_name: Zsámboki, János
last_name: Zsámboki
- first_name: David
full_name: Mazaud, David
last_name: Mazaud
- first_name: Daria E
full_name: Siekhaus, Daria E
id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
last_name: Siekhaus
orcid: 0000-0001-8323-8353
- first_name: Manolis
full_name: Fanto, Manolis
last_name: Fanto
- first_name: Angela
full_name: Giangrande, Angela
last_name: Giangrande
citation:
ama: Trébuchet G, Cattenoz PB, Zsámboki J, et al. The Repo homeodomain transcription
factor suppresses hematopoiesis in Drosophila and preserves the glial fate. Journal
of Neuroscience. 2019;39(2):238-255. doi:10.1523/JNEUROSCI.1059-18.2018
apa: Trébuchet, G., Cattenoz, P. B., Zsámboki, J., Mazaud, D., Siekhaus, D. E.,
Fanto, M., & Giangrande, A. (2019). The Repo homeodomain transcription factor
suppresses hematopoiesis in Drosophila and preserves the glial fate. Journal
of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.1059-18.2018
chicago: Trébuchet, Guillaume, Pierre B Cattenoz, János Zsámboki, David Mazaud,
Daria E Siekhaus, Manolis Fanto, and Angela Giangrande. “The Repo Homeodomain
Transcription Factor Suppresses Hematopoiesis in Drosophila and Preserves the
Glial Fate.” Journal of Neuroscience. Society for Neuroscience, 2019. https://doi.org/10.1523/JNEUROSCI.1059-18.2018.
ieee: G. Trébuchet et al., “The Repo homeodomain transcription factor suppresses
hematopoiesis in Drosophila and preserves the glial fate,” Journal of Neuroscience,
vol. 39, no. 2. Society for Neuroscience, pp. 238–255, 2019.
ista: Trébuchet G, Cattenoz PB, Zsámboki J, Mazaud D, Siekhaus DE, Fanto M, Giangrande
A. 2019. The Repo homeodomain transcription factor suppresses hematopoiesis in
Drosophila and preserves the glial fate. Journal of Neuroscience. 39(2), 238–255.
mla: Trébuchet, Guillaume, et al. “The Repo Homeodomain Transcription Factor Suppresses
Hematopoiesis in Drosophila and Preserves the Glial Fate.” Journal of Neuroscience,
vol. 39, no. 2, Society for Neuroscience, 2019, pp. 238–55, doi:10.1523/JNEUROSCI.1059-18.2018.
short: G. Trébuchet, P.B. Cattenoz, J. Zsámboki, D. Mazaud, D.E. Siekhaus, M. Fanto,
A. Giangrande, Journal of Neuroscience 39 (2019) 238–255.
date_created: 2018-12-11T11:44:07Z
date_published: 2019-01-09T00:00:00Z
date_updated: 2025-04-15T06:52:10Z
day: '09'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.1523/JNEUROSCI.1059-18.2018
ec_funded: 1
external_id:
isi:
- '000455189900006'
pmid:
- '30504274'
file:
- access_level: open_access
checksum: 8f6925eb4cd1e8747d8ea25929c68de6
content_type: application/pdf
creator: dernst
date_created: 2020-10-02T09:33:28Z
date_updated: 2020-10-02T09:33:28Z
file_id: '8596'
file_name: 2019_JournNeuroscience_Trebuchet.pdf
file_size: 9455414
relation: main_file
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file_date_updated: 2020-10-02T09:33:28Z
has_accepted_license: '1'
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month: '01'
oa: 1
oa_version: Published Version
page: 238-255
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project:
- _id: 2536F660-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '334077'
name: Investigating the role of transporters in invasive migration through junctions
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '8048'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Repo homeodomain transcription factor suppresses hematopoiesis in Drosophila
and preserves the glial fate
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 39
year: '2019'
...
---
_id: '80'
abstract:
- lang: eng
text: 'We consider an interacting, dilute Bose gas trapped in a harmonic potential
at a positive temperature. The system is analyzed in a combination of a thermodynamic
and a Gross–Pitaevskii (GP) limit where the trap frequency ω, the temperature
T, and the particle number N are related by N∼ (T/ ω) 3→ ∞ while the scattering
length is so small that the interaction energy per particle around the center
of the trap is of the same order of magnitude as the spectral gap in the trap.
We prove that the difference between the canonical free energy of the interacting
gas and the one of the noninteracting system can be obtained by minimizing the
GP energy functional. We also prove Bose–Einstein condensation in the following
sense: The one-particle density matrix of any approximate minimizer of the canonical
free energy functional is to leading order given by that of the noninteracting
gas but with the free condensate wavefunction replaced by the GP minimizer.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Andreas
full_name: Deuchert, Andreas
id: 4DA65CD0-F248-11E8-B48F-1D18A9856A87
last_name: Deuchert
orcid: 0000-0003-3146-6746
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
- first_name: Jakob
full_name: Yngvason, Jakob
last_name: Yngvason
citation:
ama: Deuchert A, Seiringer R, Yngvason J. Bose–Einstein condensation in a dilute,
trapped gas at positive temperature. Communications in Mathematical Physics.
2019;368(2):723-776. doi:10.1007/s00220-018-3239-0
apa: Deuchert, A., Seiringer, R., & Yngvason, J. (2019). Bose–Einstein condensation
in a dilute, trapped gas at positive temperature. Communications in Mathematical
Physics. Springer. https://doi.org/10.1007/s00220-018-3239-0
chicago: Deuchert, Andreas, Robert Seiringer, and Jakob Yngvason. “Bose–Einstein
Condensation in a Dilute, Trapped Gas at Positive Temperature.” Communications
in Mathematical Physics. Springer, 2019. https://doi.org/10.1007/s00220-018-3239-0.
ieee: A. Deuchert, R. Seiringer, and J. Yngvason, “Bose–Einstein condensation in
a dilute, trapped gas at positive temperature,” Communications in Mathematical
Physics, vol. 368, no. 2. Springer, pp. 723–776, 2019.
ista: Deuchert A, Seiringer R, Yngvason J. 2019. Bose–Einstein condensation in a
dilute, trapped gas at positive temperature. Communications in Mathematical Physics.
368(2), 723–776.
mla: Deuchert, Andreas, et al. “Bose–Einstein Condensation in a Dilute, Trapped
Gas at Positive Temperature.” Communications in Mathematical Physics, vol.
368, no. 2, Springer, 2019, pp. 723–76, doi:10.1007/s00220-018-3239-0.
short: A. Deuchert, R. Seiringer, J. Yngvason, Communications in Mathematical Physics
368 (2019) 723–776.
date_created: 2018-12-11T11:44:31Z
date_published: 2019-06-01T00:00:00Z
date_updated: 2025-04-14T07:27:00Z
day: '01'
ddc:
- '530'
department:
- _id: RoSe
doi: 10.1007/s00220-018-3239-0
ec_funded: 1
external_id:
isi:
- '000467796800007'
file:
- access_level: open_access
checksum: c7e9880b43ac726712c1365e9f2f73a6
content_type: application/pdf
creator: dernst
date_created: 2018-12-17T10:34:06Z
date_updated: 2020-07-14T12:48:07Z
file_id: '5688'
file_name: 2018_CommunMathPhys_Deuchert.pdf
file_size: 893902
relation: main_file
file_date_updated: 2020-07-14T12:48:07Z
has_accepted_license: '1'
intvolume: ' 368'
isi: 1
issue: '2'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 723-776
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P27533_N27
name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication: Communications in Mathematical Physics
publication_status: published
publisher: Springer
publist_id: '7974'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Bose–Einstein condensation in a dilute, trapped gas at positive temperature
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 368
year: '2019'
...
---
_id: '8175'
abstract:
- lang: eng
text: We study edge asymptotics of poissonized Plancherel-type measures on skew
Young diagrams (integer partitions). These measures can be seen as generalizations
of those studied by Baik--Deift--Johansson and Baik--Rains in resolving Ulam's
problem on longest increasing subsequences of random permutations and the last
passage percolation (corner growth) discrete versions thereof. Moreover they interpolate
between said measures and the uniform measure on partitions. In the new KPZ-like
1/3 exponent edge scaling limit with logarithmic corrections, we find new probability
distributions generalizing the classical Tracy--Widom GUE, GOE and GSE distributions
from the theory of random matrices.
acknowledgement: "D.B. is especially grateful to Patrik Ferrari for suggesting simplifications
in Section 3 and\r\nto Alessandra Occelli for suggesting the name for the models
of Section 2.\r\n"
article_number: '34'
article_processing_charge: No
arxiv: 1
author:
- first_name: Dan
full_name: Betea, Dan
last_name: Betea
- first_name: Jérémie
full_name: Bouttier, Jérémie
last_name: Bouttier
- first_name: Peter
full_name: Nejjar, Peter
id: 4BF426E2-F248-11E8-B48F-1D18A9856A87
last_name: Nejjar
- first_name: Mirjana
full_name: Vuletíc, Mirjana
last_name: Vuletíc
citation:
ama: 'Betea D, Bouttier J, Nejjar P, Vuletíc M. New edge asymptotics of skew Young
diagrams via free boundaries. In: Proceedings on the 31st International Conference
on Formal Power Series and Algebraic Combinatorics. Formal Power Series and
Algebraic Combinatorics; 2019.'
apa: 'Betea, D., Bouttier, J., Nejjar, P., & Vuletíc, M. (2019). New edge asymptotics
of skew Young diagrams via free boundaries. In Proceedings on the 31st International
Conference on Formal Power Series and Algebraic Combinatorics. Ljubljana,
Slovenia: Formal Power Series and Algebraic Combinatorics.'
chicago: Betea, Dan, Jérémie Bouttier, Peter Nejjar, and Mirjana Vuletíc. “New Edge
Asymptotics of Skew Young Diagrams via Free Boundaries.” In Proceedings on
the 31st International Conference on Formal Power Series and Algebraic Combinatorics.
Formal Power Series and Algebraic Combinatorics, 2019.
ieee: D. Betea, J. Bouttier, P. Nejjar, and M. Vuletíc, “New edge asymptotics of
skew Young diagrams via free boundaries,” in Proceedings on the 31st International
Conference on Formal Power Series and Algebraic Combinatorics, Ljubljana,
Slovenia, 2019.
ista: 'Betea D, Bouttier J, Nejjar P, Vuletíc M. 2019. New edge asymptotics of skew
Young diagrams via free boundaries. Proceedings on the 31st International Conference
on Formal Power Series and Algebraic Combinatorics. FPSAC: International Conference
on Formal Power Series and Algebraic Combinatorics, 34.'
mla: Betea, Dan, et al. “New Edge Asymptotics of Skew Young Diagrams via Free Boundaries.”
Proceedings on the 31st International Conference on Formal Power Series and
Algebraic Combinatorics, 34, Formal Power Series and Algebraic Combinatorics,
2019.
short: D. Betea, J. Bouttier, P. Nejjar, M. Vuletíc, in:, Proceedings on the 31st
International Conference on Formal Power Series and Algebraic Combinatorics, Formal
Power Series and Algebraic Combinatorics, 2019.
conference:
end_date: 2019-07-05
location: Ljubljana, Slovenia
name: 'FPSAC: International Conference on Formal Power Series and Algebraic Combinatorics'
start_date: 2019-07-01
date_created: 2020-07-26T22:01:04Z
date_published: 2019-07-01T00:00:00Z
date_updated: 2021-01-12T08:17:18Z
day: '01'
department:
- _id: LaEr
ec_funded: 1
external_id:
arxiv:
- '1902.08750'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1902.08750
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '716117'
name: Optimal Transport and Stochastic Dynamics
publication: Proceedings on the 31st International Conference on Formal Power Series
and Algebraic Combinatorics
publication_status: published
publisher: Formal Power Series and Algebraic Combinatorics
quality_controlled: '1'
scopus_import: '1'
status: public
title: New edge asymptotics of skew Young diagrams via free boundaries
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '8182'
abstract:
- lang: eng
text: "Suppose that $n\\neq p^k$ and $n\\neq 2p^k$ for all $k$ and all primes $p$.
We prove that for any Hausdorff compactum $X$ with a free action of the symmetric
group $\\mathfrak S_n$ there exists an $\\mathfrak S_n$-equivariant map $X \\to\r\n{\\mathbb
R}^n$ whose image avoids the diagonal $\\{(x,x\\dots,x)\\in {\\mathbb R}^n|x\\in
{\\mathbb R}\\}$.\r\n Previously, the special cases of this statement for certain
$X$ were usually proved using the equivartiant obstruction theory. Such calculations
are difficult and may become infeasible past the first (primary) obstruction.
We\r\ntake a different approach which allows us to prove the vanishing of all
obstructions simultaneously. The essential step in the proof is classifying the
possible degrees of $\\mathfrak S_n$-equivariant maps from the boundary\r\n$\\partial\\Delta^{n-1}$
of $(n-1)$-simplex to itself. Existence of equivariant maps between spaces is
important for many questions arising from discrete mathematics and geometry, such
as Kneser's conjecture, the Square Peg conjecture, the Splitting Necklace problem,
and the Topological Tverberg conjecture, etc. We demonstrate the utility of our
result applying it to one such question, a specific instance of envy-free division
problem."
article_number: '1910.12628'
article_processing_charge: No
arxiv: 1
author:
- first_name: Sergey
full_name: Avvakumov, Sergey
id: 3827DAC8-F248-11E8-B48F-1D18A9856A87
last_name: Avvakumov
orcid: 0000-0002-7840-5062
- first_name: Sergey
full_name: Kudrya, Sergey
id: ecf01965-d252-11ea-95a5-8ada5f6c6a67
last_name: Kudrya
citation:
ama: Avvakumov S, Kudrya S. Vanishing of all equivariant obstructions and the mapping
degree. arXiv. doi:10.48550/arXiv.1910.12628
apa: Avvakumov, S., & Kudrya, S. (n.d.). Vanishing of all equivariant obstructions
and the mapping degree. arXiv. https://doi.org/10.48550/arXiv.1910.12628
chicago: Avvakumov, Sergey, and Sergey Kudrya. “Vanishing of All Equivariant Obstructions
and the Mapping Degree.” ArXiv, n.d. https://doi.org/10.48550/arXiv.1910.12628.
ieee: S. Avvakumov and S. Kudrya, “Vanishing of all equivariant obstructions and
the mapping degree,” arXiv. .
ista: Avvakumov S, Kudrya S. Vanishing of all equivariant obstructions and the mapping
degree. arXiv, 1910.12628.
mla: Avvakumov, Sergey, and Sergey Kudrya. “Vanishing of All Equivariant Obstructions
and the Mapping Degree.” ArXiv, 1910.12628, doi:10.48550/arXiv.1910.12628.
short: S. Avvakumov, S. Kudrya, ArXiv (n.d.).
corr_author: '1'
date_created: 2020-07-30T10:45:08Z
date_published: 2019-10-28T00:00:00Z
date_updated: 2026-04-08T07:25:54Z
day: '28'
department:
- _id: UlWa
doi: 10.48550/arXiv.1910.12628
external_id:
arxiv:
- '1910.12628'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1910.12628
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 26611F5C-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P31312
name: Algorithms for Embeddings and Homotopy Theory
publication: arXiv
publication_status: draft
related_material:
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relation: dissertation_contains
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status: public
title: Vanishing of all equivariant obstructions and the mapping degree
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...