---
_id: '316'
abstract:
- lang: eng
  text: 'Self-incompatibility (SI) is a genetically based recognition system that
    functions to prevent self-fertilization and mating among related plants. An enduring
    puzzle in SI is how the high diversity observed in nature arises and is maintained.
    Based on the underlying recognition mechanism, SI can be classified into two main
    groups: self- and non-self recognition. Most work has focused on diversification
    within self-recognition systems despite expected differences between the two groups
    in the evolutionary pathways and outcomes of diversification. Here, we use a deterministic
    population genetic model and stochastic simulations to investigate how novel S-haplotypes
    evolve in a gametophytic non-self recognition (SRNase/S Locus F-box (SLF)) SI
    system. For this model the pathways for diversification involve either the maintenance
    or breakdown of SI and can vary in the order of mutations of the female (SRNase)
    and male (SLF) components. We show analytically that diversification can occur
    with high inbreeding depression and self-pollination, but this varies with evolutionary
    pathway and level of completeness (which determines the number of potential mating
    partners in the population), and in general is more likely for lower haplotype
    number. The conditions for diversification are broader in stochastic simulations
    of finite population size. However, the number of haplotypes observed under high
    inbreeding and moderate to high self-pollination is less than that commonly observed
    in nature. Diversification was observed through pathways that maintain SI as well
    as through self-compatible intermediates. Yet the lifespan of diversified haplotypes
    was sensitive to their level of completeness. By examining diversification in
    a non-self recognition SI system, this model extends our understanding of the
    evolution and maintenance of haplotype diversity observed in a self recognition
    system common in flowering plants.'
article_processing_charge: No
article_type: original
author:
- first_name: Katarina
  full_name: Bodova, Katarina
  id: 2BA24EA0-F248-11E8-B48F-1D18A9856A87
  last_name: Bodova
  orcid: 0000-0002-7214-0171
- first_name: Tadeas
  full_name: Priklopil, Tadeas
  id: 3C869AA0-F248-11E8-B48F-1D18A9856A87
  last_name: Priklopil
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Melinda
  full_name: Pickup, Melinda
  id: 2C78037E-F248-11E8-B48F-1D18A9856A87
  last_name: Pickup
  orcid: 0000-0001-6118-0541
citation:
  ama: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. Evolutionary pathways
    for the generation of new self-incompatibility haplotypes in a non-self recognition
    system. <i>Genetics</i>. 2018;209(3):861-883. doi:<a href="https://doi.org/10.1534/genetics.118.300748">10.1534/genetics.118.300748</a>
  apa: Bodova, K., Priklopil, T., Field, D., Barton, N. H., &#38; Pickup, M. (2018).
    Evolutionary pathways for the generation of new self-incompatibility haplotypes
    in a non-self recognition system. <i>Genetics</i>. Genetics Society of America.
    <a href="https://doi.org/10.1534/genetics.118.300748">https://doi.org/10.1534/genetics.118.300748</a>
  chicago: Bodova, Katarina, Tadeas Priklopil, David Field, Nicholas H Barton, and
    Melinda Pickup. “Evolutionary Pathways for the Generation of New Self-Incompatibility
    Haplotypes in a Non-Self Recognition System.” <i>Genetics</i>. Genetics Society
    of America, 2018. <a href="https://doi.org/10.1534/genetics.118.300748">https://doi.org/10.1534/genetics.118.300748</a>.
  ieee: K. Bodova, T. Priklopil, D. Field, N. H. Barton, and M. Pickup, “Evolutionary
    pathways for the generation of new self-incompatibility haplotypes in a non-self
    recognition system,” <i>Genetics</i>, vol. 209, no. 3. Genetics Society of America,
    pp. 861–883, 2018.
  ista: Bodova K, Priklopil T, Field D, Barton NH, Pickup M. 2018. Evolutionary pathways
    for the generation of new self-incompatibility haplotypes in a non-self recognition
    system. Genetics. 209(3), 861–883.
  mla: Bodova, Katarina, et al. “Evolutionary Pathways for the Generation of New Self-Incompatibility
    Haplotypes in a Non-Self Recognition System.” <i>Genetics</i>, vol. 209, no. 3,
    Genetics Society of America, 2018, pp. 861–83, doi:<a href="https://doi.org/10.1534/genetics.118.300748">10.1534/genetics.118.300748</a>.
  short: K. Bodova, T. Priklopil, D. Field, N.H. Barton, M. Pickup, Genetics 209 (2018)
    861–883.
date_created: 2018-12-11T11:45:47Z
date_published: 2018-07-01T00:00:00Z
date_updated: 2025-04-15T06:50:00Z
day: '01'
department:
- _id: NiBa
- _id: GaTk
doi: 10.1534/genetics.118.300748
ec_funded: 1
external_id:
  isi:
  - '000437171700017'
intvolume: '       209'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.biorxiv.org/node/80098.abstract
month: '07'
oa: 1
oa_version: Preprint
page: 861-883
project:
- _id: 25B36484-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '329960'
  name: Mating system and the evolutionary dynamics of hybrid zones
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Genetics
publication_status: published
publisher: Genetics Society of America
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/recognizing-others-but-not-yourself-new-insights-into-the-evolution-of-plant-mating/
  record:
  - id: '9813'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Evolutionary pathways for the generation of new self-incompatibility haplotypes
  in a non-self recognition system
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 209
year: '2018'
...
---
_id: '317'
abstract:
- lang: eng
  text: We replace the established aluminium gates for the formation of quantum dots
    in silicon with gates made from palladium. We study the morphology of both aluminium
    and palladium gates with transmission electron microscopy. The native aluminium
    oxide is found to be formed all around the aluminium gates, which could lead to
    the formation of unintentional dots. Therefore, we report on a novel fabrication
    route that replaces aluminium and its native oxide by palladium with atomic-layer-deposition-grown
    aluminium oxide. Using this approach, we show the formation of low-disorder gate-defined
    quantum dots, which are reproducibly fabricated. Furthermore, palladium enables
    us to further shrink the gate design, allowing us to perform electron transport
    measurements in the few-electron regime in devices comprising only two gate layers,
    a major technological advancement. It remains to be seen, whether the introduction
    of palladium gates can improve the excellent results on electron and nuclear spin
    qubits defined with an aluminium gate stack.
article_number: '5690'
article_processing_charge: No
author:
- first_name: Matthias
  full_name: Brauns, Matthias
  id: 33F94E3C-F248-11E8-B48F-1D18A9856A87
  last_name: Brauns
- first_name: Sergey
  full_name: Amitonov, Sergey
  last_name: Amitonov
- first_name: Paul
  full_name: Spruijtenburg, Paul
  last_name: Spruijtenburg
- first_name: Floris
  full_name: Zwanenburg, Floris
  last_name: Zwanenburg
citation:
  ama: Brauns M, Amitonov S, Spruijtenburg P, Zwanenburg F. Palladium gates for reproducible
    quantum dots in silicon. <i>Scientific Reports</i>. 2018;8(1). doi:<a href="https://doi.org/10.1038/s41598-018-24004-y">10.1038/s41598-018-24004-y</a>
  apa: Brauns, M., Amitonov, S., Spruijtenburg, P., &#38; Zwanenburg, F. (2018). Palladium
    gates for reproducible quantum dots in silicon. <i>Scientific Reports</i>. Nature
    Publishing Group. <a href="https://doi.org/10.1038/s41598-018-24004-y">https://doi.org/10.1038/s41598-018-24004-y</a>
  chicago: Brauns, Matthias, Sergey Amitonov, Paul Spruijtenburg, and Floris Zwanenburg.
    “Palladium Gates for Reproducible Quantum Dots in Silicon.” <i>Scientific Reports</i>.
    Nature Publishing Group, 2018. <a href="https://doi.org/10.1038/s41598-018-24004-y">https://doi.org/10.1038/s41598-018-24004-y</a>.
  ieee: M. Brauns, S. Amitonov, P. Spruijtenburg, and F. Zwanenburg, “Palladium gates
    for reproducible quantum dots in silicon,” <i>Scientific Reports</i>, vol. 8,
    no. 1. Nature Publishing Group, 2018.
  ista: Brauns M, Amitonov S, Spruijtenburg P, Zwanenburg F. 2018. Palladium gates
    for reproducible quantum dots in silicon. Scientific Reports. 8(1), 5690.
  mla: Brauns, Matthias, et al. “Palladium Gates for Reproducible Quantum Dots in
    Silicon.” <i>Scientific Reports</i>, vol. 8, no. 1, 5690, Nature Publishing Group,
    2018, doi:<a href="https://doi.org/10.1038/s41598-018-24004-y">10.1038/s41598-018-24004-y</a>.
  short: M. Brauns, S. Amitonov, P. Spruijtenburg, F. Zwanenburg, Scientific Reports
    8 (2018).
corr_author: '1'
date_created: 2018-12-11T11:45:47Z
date_published: 2018-04-09T00:00:00Z
date_updated: 2024-10-09T20:58:34Z
day: '09'
ddc:
- '539'
department:
- _id: GeKa
doi: 10.1038/s41598-018-24004-y
external_id:
  isi:
  - '000429404300013'
file:
- access_level: open_access
  checksum: 20af238ca4ba6491b77270be8d826bf5
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:04Z
  date_updated: 2020-07-14T12:46:02Z
  file_id: '5256'
  file_name: IST-2018-1016-v1+1_2018_Brauns_Palladium_gates.pdf
  file_size: 1850530
  relation: main_file
file_date_updated: 2020-07-14T12:46:02Z
has_accepted_license: '1'
intvolume: '         8'
isi: 1
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_status: published
publisher: Nature Publishing Group
publist_id: '7548'
pubrep_id: '1016'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Palladium gates for reproducible quantum dots in silicon
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8
year: '2018'
...
---
_id: '318'
abstract:
- lang: eng
  text: The insect’s fat body combines metabolic and immunological functions. In this
    issue of Developmental Cell, Franz et al. (2018) show that in Drosophila, cells
    of the fat body are not static, but can actively “swim” toward sites of epithelial
    injury, where they physically clog the wound and locally secrete antimicrobial
    peptides.
acknowledgement: Short Survey
article_processing_charge: No
author:
- first_name: Alessandra M
  full_name: Casano, Alessandra M
  id: 3DBA3F4E-F248-11E8-B48F-1D18A9856A87
  last_name: Casano
  orcid: 0000-0002-6009-6804
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Casano AM, Sixt MK. A fat lot of good for wound healing. <i>Developmental Cell</i>.
    2018;44(4):405-406. doi:<a href="https://doi.org/10.1016/j.devcel.2018.02.009">10.1016/j.devcel.2018.02.009</a>
  apa: Casano, A. M., &#38; Sixt, M. K. (2018). A fat lot of good for wound healing.
    <i>Developmental Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.devcel.2018.02.009">https://doi.org/10.1016/j.devcel.2018.02.009</a>
  chicago: Casano, Alessandra M, and Michael K Sixt. “A Fat Lot of Good for Wound
    Healing.” <i>Developmental Cell</i>. Cell Press, 2018. <a href="https://doi.org/10.1016/j.devcel.2018.02.009">https://doi.org/10.1016/j.devcel.2018.02.009</a>.
  ieee: A. M. Casano and M. K. Sixt, “A fat lot of good for wound healing,” <i>Developmental
    Cell</i>, vol. 44, no. 4. Cell Press, pp. 405–406, 2018.
  ista: Casano AM, Sixt MK. 2018. A fat lot of good for wound healing. Developmental
    Cell. 44(4), 405–406.
  mla: Casano, Alessandra M., and Michael K. Sixt. “A Fat Lot of Good for Wound Healing.”
    <i>Developmental Cell</i>, vol. 44, no. 4, Cell Press, 2018, pp. 405–06, doi:<a
    href="https://doi.org/10.1016/j.devcel.2018.02.009">10.1016/j.devcel.2018.02.009</a>.
  short: A.M. Casano, M.K. Sixt, Developmental Cell 44 (2018) 405–406.
corr_author: '1'
date_created: 2018-12-11T11:45:47Z
date_published: 2018-02-26T00:00:00Z
date_updated: 2024-10-09T20:58:17Z
day: '26'
department:
- _id: MiSi
doi: 10.1016/j.devcel.2018.02.009
external_id:
  isi:
  - '000426150700002'
  pmid:
  - '29486189'
intvolume: '        44'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/29486189
month: '02'
oa: 1
oa_version: Published Version
page: 405 - 406
pmid: 1
publication: Developmental Cell
publication_status: published
publisher: Cell Press
publist_id: '7547'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A fat lot of good for wound healing
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 44
year: '2018'
...
---
_id: '32'
abstract:
- lang: eng
  text: The functional role of AMPA receptor (AMPAR)-mediated synaptic signaling between
    neurons and oligodendrocyte precursor cells (OPCs) remains enigmatic. We modified
    the properties of AMPARs at axon-OPC synapses in the mouse corpus callosum in
    vivo during the peak of myelination by targeting the GluA2 subunit. Expression
    of the unedited (Ca2+ permeable) or the pore-dead GluA2 subunit of AMPARs triggered
    proliferation of OPCs and reduced their differentiation into oligodendrocytes.
    Expression of the cytoplasmic C-terminal (GluA2(813-862)) of the GluA2 subunit
    (C-tail), a modification designed to affect the interaction between GluA2 and
    AMPAR-binding proteins and to perturb trafficking of GluA2-containing AMPARs,
    decreased the differentiation of OPCs without affecting their proliferation. These
    findings suggest that ionotropic and non-ionotropic properties of AMPARs in OPCs,
    as well as specific aspects of AMPAR-mediated signaling at axon-OPC synapses in
    the mouse corpus callosum, are important for balancing the response of OPCs to
    proliferation and differentiation cues. In the brain, oligodendrocyte precursor
    cells (OPCs) receive glutamatergic AMPA-receptor-mediated synaptic input from
    neurons. Chen et al. show that modifying AMPA-receptor properties at axon-OPC
    synapses alters proliferation and differentiation of OPCs. This expands the traditional
    view of synaptic transmission by suggesting neurons also use synapses to modulate
    behavior of glia.
acknowledgement: This work was supported by Deutsche Forschungsgemeinschaft (DFG)
  grant KU2569/1-1 (to M.K.); DFG project EXC307Centre for Integrative Neuroscience
  (CIN), including grant Pool Project 2011-12 (jointly to M.K. and I.E.); and the
  Charitable Hertie Foundation (to I.E.). CIN is an Excellence Cluster funded by the
  DFG within the framework of the Excellence Initiative for 2008–2018. M.K. is supported
  by the Tistou & Charlotte Kerstan Foundation.
article_processing_charge: No
author:
- first_name: Ting
  full_name: Chen, Ting
  last_name: Chen
- first_name: Bartosz
  full_name: Kula, Bartosz
  last_name: Kula
- first_name: Balint
  full_name: Nagy, Balint
  id: 30F830CE-02D1-11E9-9BAA-DAF4881429F2
  last_name: Nagy
  orcid: 0000-0002-4002-4686
- first_name: Ruxandra
  full_name: Barzan, Ruxandra
  last_name: Barzan
- first_name: Andrea
  full_name: Gall, Andrea
  last_name: Gall
- first_name: Ingrid
  full_name: Ehrlich, Ingrid
  last_name: Ehrlich
- first_name: Maria
  full_name: Kukley, Maria
  last_name: Kukley
citation:
  ama: Chen T, Kula B, Nagy B, et al. In Vivo regulation of Oligodendrocyte processor
    cell proliferation and differentiation by the AMPA-receptor Subunit GluA2. <i>Cell
    Reports</i>. 2018;25(4):852-861.e7. doi:<a href="https://doi.org/10.1016/j.celrep.2018.09.066">10.1016/j.celrep.2018.09.066</a>
  apa: Chen, T., Kula, B., Nagy, B., Barzan, R., Gall, A., Ehrlich, I., &#38; Kukley,
    M. (2018). In Vivo regulation of Oligodendrocyte processor cell proliferation
    and differentiation by the AMPA-receptor Subunit GluA2. <i>Cell Reports</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.celrep.2018.09.066">https://doi.org/10.1016/j.celrep.2018.09.066</a>
  chicago: Chen, Ting, Bartosz Kula, Balint Nagy, Ruxandra Barzan, Andrea Gall, Ingrid
    Ehrlich, and Maria Kukley. “In Vivo Regulation of Oligodendrocyte Processor Cell
    Proliferation and Differentiation by the AMPA-Receptor Subunit GluA2.” <i>Cell
    Reports</i>. Elsevier, 2018. <a href="https://doi.org/10.1016/j.celrep.2018.09.066">https://doi.org/10.1016/j.celrep.2018.09.066</a>.
  ieee: T. Chen <i>et al.</i>, “In Vivo regulation of Oligodendrocyte processor cell
    proliferation and differentiation by the AMPA-receptor Subunit GluA2,” <i>Cell
    Reports</i>, vol. 25, no. 4. Elsevier, p. 852–861.e7, 2018.
  ista: Chen T, Kula B, Nagy B, Barzan R, Gall A, Ehrlich I, Kukley M. 2018. In Vivo
    regulation of Oligodendrocyte processor cell proliferation and differentiation
    by the AMPA-receptor Subunit GluA2. Cell Reports. 25(4), 852–861.e7.
  mla: Chen, Ting, et al. “In Vivo Regulation of Oligodendrocyte Processor Cell Proliferation
    and Differentiation by the AMPA-Receptor Subunit GluA2.” <i>Cell Reports</i>,
    vol. 25, no. 4, Elsevier, 2018, p. 852–861.e7, doi:<a href="https://doi.org/10.1016/j.celrep.2018.09.066">10.1016/j.celrep.2018.09.066</a>.
  short: T. Chen, B. Kula, B. Nagy, R. Barzan, A. Gall, I. Ehrlich, M. Kukley, Cell
    Reports 25 (2018) 852–861.e7.
date_created: 2018-12-11T11:44:16Z
date_published: 2018-10-23T00:00:00Z
date_updated: 2023-09-11T14:13:32Z
day: '23'
ddc:
- '570'
department:
- _id: SaSi
doi: 10.1016/j.celrep.2018.09.066
external_id:
  isi:
  - '000448219500005'
file:
- access_level: open_access
  checksum: d9f74277fd57176e04732707d575cf08
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T12:42:57Z
  date_updated: 2020-07-14T12:46:03Z
  file_id: '5703'
  file_name: 2018_CellReports_Chen.pdf
  file_size: 4461997
  relation: main_file
file_date_updated: 2020-07-14T12:46:03Z
has_accepted_license: '1'
intvolume: '        25'
isi: 1
issue: '4'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 852 - 861.e7
publication: Cell Reports
publication_status: published
publisher: Elsevier
publist_id: '8023'
quality_controlled: '1'
scopus_import: '1'
status: public
title: In Vivo regulation of Oligodendrocyte processor cell proliferation and differentiation
  by the AMPA-receptor Subunit GluA2
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 25
year: '2018'
...
---
_id: '320'
abstract:
- lang: eng
  text: 'Fast-spiking, parvalbumin-expressing GABAergic interneurons (PV+-BCs) express
    a complex machinery of rapid signaling mechanisms, including specialized voltage-gated
    ion channels to generate brief action potentials (APs). However, short APs are
    associated with overlapping Na+ and K+ fluxes and are therefore energetically
    expensive. How the potentially vicious combination of high AP frequency and inefficient
    spike generation can be reconciled with limited energy supply is presently unclear.
    To address this question, we performed direct recordings from the PV+-BC axon,
    the subcellular structure where active conductances for AP initiation and propagation
    are located. Surprisingly, the energy required for the AP was, on average, only
    ∼1.6 times the theoretical minimum. High energy efficiency emerged from the combination
    of fast inactivation of Na+ channels and delayed activation of Kv3-type K+ channels,
    which minimized ion flux overlap during APs. Thus, the complementary tuning of
    axonal Na+ and K+ channel gating optimizes both fast signaling properties and
    metabolic efficiency. Hu et al. demonstrate that action potentials in parvalbumin-expressing
    GABAergic interneuron axons are energetically efficient, which is highly unexpected
    given their brief duration. High energy efficiency emerges from the combination
    of fast inactivation of voltage-gated Na+ channels and delayed activation of Kv3
    channels in the axon. '
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Hua
  full_name: Hu, Hua
  id: 4AC0145C-F248-11E8-B48F-1D18A9856A87
  last_name: Hu
- first_name: Fabian
  full_name: Roth, Fabian
  last_name: Roth
- first_name: David H
  full_name: Vandael, David H
  id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
  last_name: Vandael
  orcid: 0000-0001-7577-1676
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Hu H, Roth F, Vandael DH, Jonas PM. Complementary tuning of Na+ and K+ channel
    gating underlies fast and energy-efficient action potentials in GABAergic interneuron
    axons. <i>Neuron</i>. 2018;98(1):156-165. doi:<a href="https://doi.org/10.1016/j.neuron.2018.02.024">10.1016/j.neuron.2018.02.024</a>
  apa: Hu, H., Roth, F., Vandael, D. H., &#38; Jonas, P. M. (2018). Complementary
    tuning of Na+ and K+ channel gating underlies fast and energy-efficient action
    potentials in GABAergic interneuron axons. <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2018.02.024">https://doi.org/10.1016/j.neuron.2018.02.024</a>
  chicago: Hu, Hua, Fabian Roth, David H Vandael, and Peter M Jonas. “Complementary
    Tuning of Na+ and K+ Channel Gating Underlies Fast and Energy-Efficient Action
    Potentials in GABAergic Interneuron Axons.” <i>Neuron</i>. Elsevier, 2018. <a
    href="https://doi.org/10.1016/j.neuron.2018.02.024">https://doi.org/10.1016/j.neuron.2018.02.024</a>.
  ieee: H. Hu, F. Roth, D. H. Vandael, and P. M. Jonas, “Complementary tuning of Na+
    and K+ channel gating underlies fast and energy-efficient action potentials in
    GABAergic interneuron axons,” <i>Neuron</i>, vol. 98, no. 1. Elsevier, pp. 156–165,
    2018.
  ista: Hu H, Roth F, Vandael DH, Jonas PM. 2018. Complementary tuning of Na+ and
    K+ channel gating underlies fast and energy-efficient action potentials in GABAergic
    interneuron axons. Neuron. 98(1), 156–165.
  mla: Hu, Hua, et al. “Complementary Tuning of Na+ and K+ Channel Gating Underlies
    Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons.” <i>Neuron</i>,
    vol. 98, no. 1, Elsevier, 2018, pp. 156–65, doi:<a href="https://doi.org/10.1016/j.neuron.2018.02.024">10.1016/j.neuron.2018.02.024</a>.
  short: H. Hu, F. Roth, D.H. Vandael, P.M. Jonas, Neuron 98 (2018) 156–165.
corr_author: '1'
date_created: 2018-12-11T11:45:48Z
date_published: 2018-04-04T00:00:00Z
date_updated: 2025-04-15T08:29:04Z
day: '04'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1016/j.neuron.2018.02.024
ec_funded: 1
external_id:
  isi:
  - '000429192100016'
file:
- access_level: open_access
  checksum: 76070f3729f9c603e1080d0151aa2b11
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T10:37:50Z
  date_updated: 2020-07-14T12:46:03Z
  file_id: '5690'
  file_name: 2018_Neuron_Hu.pdf
  file_size: 3180444
  relation: main_file
file_date_updated: 2020-07-14T12:46:03Z
has_accepted_license: '1'
intvolume: '        98'
isi: 1
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 156 - 165
project:
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '268548'
  name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '692692'
  name: Biophysics and circuit function of a giant cortical glutamatergic synapse
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P24909-B24
  name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00312
  name: Synaptic communication in neuronal microcircuits
publication: Neuron
publication_status: published
publisher: Elsevier
publist_id: '7545'
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/a-certain-type-of-neurons-is-more-energy-efficient-than-previously-assumed/
scopus_import: '1'
status: public
title: Complementary tuning of Na+ and K+ channel gating underlies fast and energy-efficient
  action potentials in GABAergic interneuron axons
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 98
year: '2018'
...
---
_id: '321'
abstract:
- lang: eng
  text: The twelve papers in this special section focus on learning systems with shared
    information for computer vision and multimedia communication analysis. In the
    real world, a realistic setting for computer vision or multimedia recognition
    problems is that we have some classes containing lots of training data and many
    classes containing a small amount of training data. Therefore, how to use frequent
    classes to help learning rare classes for which it is harder to collect the training
    data is an open question. Learning with shared information is an emerging topic
    in machine learning, computer vision and multimedia analysis. There are different
    levels of components that can be shared during concept modeling and machine learning
    stages, such as sharing generic object parts, sharing attributes, sharing transformations,
    sharing regularization parameters and sharing training examples, etc. Regarding
    the specific methods, multi-task learning, transfer learning and deep learning
    can be seen as using different strategies to share information. These learning
    with shared information methods are very effective in solving real-world large-scale
    problems.
article_processing_charge: No
article_type: original
author:
- first_name: Trevor
  full_name: Darrell, Trevor
  last_name: Darrell
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
- first_name: Nico
  full_name: Sebe, Nico
  last_name: Sebe
- first_name: Ying
  full_name: Wu, Ying
  last_name: Wu
- first_name: Yan
  full_name: Yan, Yan
  last_name: Yan
citation:
  ama: Darrell T, Lampert C, Sebe N, Wu Y, Yan Y. Guest editors’ introduction to the
    special section on learning with Shared information for computer vision and multimedia
    analysis. <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>.
    2018;40(5):1029-1031. doi:<a href="https://doi.org/10.1109/TPAMI.2018.2804998">10.1109/TPAMI.2018.2804998</a>
  apa: Darrell, T., Lampert, C., Sebe, N., Wu, Y., &#38; Yan, Y. (2018). Guest editors’
    introduction to the special section on learning with Shared information for computer
    vision and multimedia analysis. <i>IEEE Transactions on Pattern Analysis and Machine
    Intelligence</i>. IEEE. <a href="https://doi.org/10.1109/TPAMI.2018.2804998">https://doi.org/10.1109/TPAMI.2018.2804998</a>
  chicago: Darrell, Trevor, Christoph Lampert, Nico Sebe, Ying Wu, and Yan Yan. “Guest
    Editors’ Introduction to the Special Section on Learning with Shared Information
    for Computer Vision and Multimedia Analysis.” <i>IEEE Transactions on Pattern
    Analysis and Machine Intelligence</i>. IEEE, 2018. <a href="https://doi.org/10.1109/TPAMI.2018.2804998">https://doi.org/10.1109/TPAMI.2018.2804998</a>.
  ieee: T. Darrell, C. Lampert, N. Sebe, Y. Wu, and Y. Yan, “Guest editors’ introduction
    to the special section on learning with Shared information for computer vision
    and multimedia analysis,” <i>IEEE Transactions on Pattern Analysis and Machine
    Intelligence</i>, vol. 40, no. 5. IEEE, pp. 1029–1031, 2018.
  ista: Darrell T, Lampert C, Sebe N, Wu Y, Yan Y. 2018. Guest editors’ introduction
    to the special section on learning with Shared information for computer vision
    and multimedia analysis. IEEE Transactions on Pattern Analysis and Machine Intelligence.
    40(5), 1029–1031.
  mla: Darrell, Trevor, et al. “Guest Editors’ Introduction to the Special Section
    on Learning with Shared Information for Computer Vision and Multimedia Analysis.”
    <i>IEEE Transactions on Pattern Analysis and Machine Intelligence</i>, vol. 40,
    no. 5, IEEE, 2018, pp. 1029–31, doi:<a href="https://doi.org/10.1109/TPAMI.2018.2804998">10.1109/TPAMI.2018.2804998</a>.
  short: T. Darrell, C. Lampert, N. Sebe, Y. Wu, Y. Yan, IEEE Transactions on Pattern
    Analysis and Machine Intelligence 40 (2018) 1029–1031.
corr_author: '1'
date_created: 2018-12-11T11:45:48Z
date_published: 2018-05-01T00:00:00Z
date_updated: 2024-10-09T20:58:26Z
day: '01'
ddc:
- '000'
department:
- _id: ChLa
doi: 10.1109/TPAMI.2018.2804998
external_id:
  isi:
  - '000428901200001'
file:
- access_level: open_access
  checksum: b19c75da06faf3291a3ca47dfa50ef63
  content_type: application/pdf
  creator: dernst
  date_created: 2020-05-14T12:50:48Z
  date_updated: 2020-07-14T12:46:03Z
  file_id: '7835'
  file_name: 2018_IEEE_Darrell.pdf
  file_size: 141724
  relation: main_file
file_date_updated: 2020-07-14T12:46:03Z
has_accepted_license: '1'
intvolume: '        40'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 1029 - 1031
publication: IEEE Transactions on Pattern Analysis and Machine Intelligence
publication_status: published
publisher: IEEE
publist_id: '7544'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Guest editors' introduction to the special section on learning with Shared
  information for computer vision and multimedia analysis
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 40
year: '2018'
...
---
_id: '322'
abstract:
- lang: eng
  text: We construct quantizations of multiplicative hypertoric varieties using an
    algebra of q-difference operators on affine space, where q is a root of unity
    in C. The quantization defines a matrix bundle (i.e. Azumaya algebra) over the
    multiplicative hypertoric variety and admits an explicit finite étale splitting.
    The global sections of this Azumaya algebra is a hypertoric quantum group, and
    we prove a localization theorem. We introduce a general framework of Frobenius
    quantum moment maps and their Hamiltonian reductions; our results shed light on
    an instance of this framework.
acknowledgement: "National Science Foundation: Graduate Research Fellowship and grant
  No.0932078000; ERC Advanced Grant “Arithmetic and Physics of Higgs moduli spaces”
  No. 320593 \r\nThe author is grateful to David Jordan for suggesting this project
  and providing guidance throughout, particularly for the formulation of Frobenius
  quantum moment maps and key ideas in the proofs of Theorems 3.12 and 4.8. Special
  thanks to David Ben-Zvi (the author's PhD advisor) for numerous discussions and
  constant encouragement, and for suggesting the term ‘hypertoric quantum group.’
  Many results appearing in the current paper were proven independently by Nicholas
  Cooney; the author is grateful to Nicholas for sharing his insight on various topics,
  including Proposition 3.8. The author also thanks Nicholas Proudfoot for relating
  the definition of multiplicative hypertoric varieties, as well as the content of
  Remark 2.14. The author also benefited immensely from the close reading and detailed
  comments of an anonymous referee, and from conversations with Justin Hilburn, Kobi
  Kremnitzer, Michael McBreen, Tom Nevins, Travis Schedler, and Ben Webster. \r\n\r\n\r\n\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Iordan V
  full_name: Ganev, Iordan V
  id: 447491B8-F248-11E8-B48F-1D18A9856A87
  last_name: Ganev
citation:
  ama: Ganev IV. Quantizations of multiplicative hypertoric varieties at a root of
    unity. <i>Journal of Algebra</i>. 2018;506:92-128. doi:<a href="https://doi.org/10.1016/j.jalgebra.2018.03.015">10.1016/j.jalgebra.2018.03.015</a>
  apa: Ganev, I. V. (2018). Quantizations of multiplicative hypertoric varieties at
    a root of unity. <i>Journal of Algebra</i>. World Scientific Publishing. <a href="https://doi.org/10.1016/j.jalgebra.2018.03.015">https://doi.org/10.1016/j.jalgebra.2018.03.015</a>
  chicago: Ganev, Iordan V. “Quantizations of Multiplicative Hypertoric Varieties
    at a Root of Unity.” <i>Journal of Algebra</i>. World Scientific Publishing, 2018.
    <a href="https://doi.org/10.1016/j.jalgebra.2018.03.015">https://doi.org/10.1016/j.jalgebra.2018.03.015</a>.
  ieee: I. V. Ganev, “Quantizations of multiplicative hypertoric varieties at a root
    of unity,” <i>Journal of Algebra</i>, vol. 506. World Scientific Publishing, pp.
    92–128, 2018.
  ista: Ganev IV. 2018. Quantizations of multiplicative hypertoric varieties at a
    root of unity. Journal of Algebra. 506, 92–128.
  mla: Ganev, Iordan V. “Quantizations of Multiplicative Hypertoric Varieties at a
    Root of Unity.” <i>Journal of Algebra</i>, vol. 506, World Scientific Publishing,
    2018, pp. 92–128, doi:<a href="https://doi.org/10.1016/j.jalgebra.2018.03.015">10.1016/j.jalgebra.2018.03.015</a>.
  short: I.V. Ganev, Journal of Algebra 506 (2018) 92–128.
corr_author: '1'
date_created: 2018-12-11T11:45:49Z
date_published: 2018-07-15T00:00:00Z
date_updated: 2025-04-14T09:12:46Z
day: '15'
department:
- _id: TaHa
doi: 10.1016/j.jalgebra.2018.03.015
ec_funded: 1
external_id:
  arxiv:
  - '1412.7211'
  isi:
  - '000433270600005'
intvolume: '       506'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1412.7211
month: '07'
oa: 1
oa_version: Preprint
page: 92 - 128
project:
- _id: 25E549F4-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '320593'
  name: Arithmetic and physics of Higgs moduli spaces
publication: Journal of Algebra
publication_status: published
publisher: World Scientific Publishing
publist_id: '7543'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantizations of multiplicative hypertoric varieties at a root of unity
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 506
year: '2018'
...
---
_id: '325'
abstract:
- lang: eng
  text: Probabilistic programs extend classical imperative programs with real-valued
    random variables and random branching. The most basic liveness property for such
    programs is the termination property. The qualitative (aka almost-sure) termination
    problem asks whether a given program program terminates with probability 1. While
    ranking functions provide a sound and complete method for non-probabilistic programs,
    the extension of them to probabilistic programs is achieved via ranking supermartingales
    (RSMs). Although deep theoretical results have been established about RSMs, their
    application to probabilistic programs with nondeterminism has been limited only
    to programs of restricted control-flow structure. For non-probabilistic programs,
    lexicographic ranking functions provide a compositional and practical approach
    for termination analysis of real-world programs. In this work we introduce lexicographic
    RSMs and show that they present a sound method for almost-sure termination of
    probabilistic programs with nondeterminism. We show that lexicographic RSMs provide
    a tool for compositional reasoning about almost-sure termination, and for probabilistic
    programs with linear arithmetic they can be synthesized efficiently (in polynomial
    time). We also show that with additional restrictions even asymptotic bounds on
    expected termination time can be obtained through lexicographic RSMs. Finally,
    we present experimental results on benchmarks adapted from previous work to demonstrate
    the effectiveness of our approach.
article_number: '34'
arxiv: 1
author:
- first_name: Sheshansh
  full_name: Agrawal, Sheshansh
  last_name: Agrawal
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Petr
  full_name: Novotny, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotny
citation:
  ama: 'Agrawal S, Chatterjee K, Novotný P. Lexicographic ranking supermartingales:
    an efficient approach to termination of probabilistic programs. In: Vol 2. ACM;
    2018. doi:<a href="https://doi.org/10.1145/3158122">10.1145/3158122</a>'
  apa: 'Agrawal, S., Chatterjee, K., &#38; Novotný, P. (2018). Lexicographic ranking
    supermartingales: an efficient approach to termination of probabilistic programs
    (Vol. 2). Presented at the POPL: Principles of Programming Languages, Los Angeles,
    CA, USA: ACM. <a href="https://doi.org/10.1145/3158122">https://doi.org/10.1145/3158122</a>'
  chicago: 'Agrawal, Sheshansh, Krishnendu Chatterjee, and Petr Novotný. “Lexicographic
    Ranking Supermartingales: An Efficient Approach to Termination of Probabilistic
    Programs,” Vol. 2. ACM, 2018. <a href="https://doi.org/10.1145/3158122">https://doi.org/10.1145/3158122</a>.'
  ieee: 'S. Agrawal, K. Chatterjee, and P. Novotný, “Lexicographic ranking supermartingales:
    an efficient approach to termination of probabilistic programs,” presented at
    the POPL: Principles of Programming Languages, Los Angeles, CA, USA, 2018, vol.
    2, no. POPL.'
  ista: 'Agrawal S, Chatterjee K, Novotný P. 2018. Lexicographic ranking supermartingales:
    an efficient approach to termination of probabilistic programs. POPL: Principles
    of Programming Languages vol. 2, 34.'
  mla: 'Agrawal, Sheshansh, et al. <i>Lexicographic Ranking Supermartingales: An Efficient
    Approach to Termination of Probabilistic Programs</i>. Vol. 2, no. POPL, 34, ACM,
    2018, doi:<a href="https://doi.org/10.1145/3158122">10.1145/3158122</a>.'
  short: S. Agrawal, K. Chatterjee, P. Novotný, in:, ACM, 2018.
conference:
  end_date: 2018-01-13
  location: Los Angeles, CA, USA
  name: 'POPL: Principles of Programming Languages'
  start_date: 2018-01-07
date_created: 2018-12-11T11:45:50Z
date_published: 2018-01-01T00:00:00Z
date_updated: 2024-10-21T06:02:40Z
day: '01'
department:
- _id: KrCh
doi: 10.1145/3158122
external_id:
  arxiv:
  - '1709.04037'
intvolume: '         2'
issue: POPL
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1709.04037
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication_status: published
publisher: ACM
publist_id: '7540'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Lexicographic ranking supermartingales: an efficient approach to termination
  of probabilistic programs'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2
year: '2018'
...
---
_id: '326'
abstract:
- lang: eng
  text: Three-dimensional (3D) super-resolution microscopy technique structured illumination
    microscopy (SIM) imaging of dendritic spines along the dendrite has not been previously
    performed in fixed tissues, mainly due to deterioration of the stripe pattern
    of the excitation laser induced by light scattering and optical aberrations. To
    address this issue and solve these optical problems, we applied a novel clearing
    reagent, LUCID, to fixed brains. In SIM imaging, the penetration depth and the
    spatial resolution were improved in LUCID-treated slices, and 160-nm spatial resolution
    was obtained in a large portion of the imaging volume on a single apical dendrite.
    Furthermore, in a morphological analysis of spine heads of layer V pyramidal neurons
    (L5PNs) in the medial prefrontal cortex (mPFC) of chronic dexamethasone (Dex)-treated
    mice, SIM imaging revealed an altered distribution of spine forms that could not
    be detected by high-NA confocal imaging. Thus, super-resolution SIM imaging represents
    a promising high-throughput method for revealing spine morphologies in single
    dendrites.
acknowledged_ssus:
- _id: EM-Fac
article_processing_charge: No
author:
- first_name: Kazuaki
  full_name: Sawada, Kazuaki
  last_name: Sawada
- first_name: Ryosuke
  full_name: Kawakami, Ryosuke
  last_name: Kawakami
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Tomomi
  full_name: Nemoto, Tomomi
  last_name: Nemoto
citation:
  ama: Sawada K, Kawakami R, Shigemoto R, Nemoto T. Super resolution structural analysis
    of dendritic spines using three-dimensional structured illumination microscopy
    in cleared mouse brain slices. <i>European Journal of Neuroscience</i>. 2018;47(9):1033-1042.
    doi:<a href="https://doi.org/10.1111/ejn.13901">10.1111/ejn.13901</a>
  apa: Sawada, K., Kawakami, R., Shigemoto, R., &#38; Nemoto, T. (2018). Super resolution
    structural analysis of dendritic spines using three-dimensional structured illumination
    microscopy in cleared mouse brain slices. <i>European Journal of Neuroscience</i>.
    Wiley. <a href="https://doi.org/10.1111/ejn.13901">https://doi.org/10.1111/ejn.13901</a>
  chicago: Sawada, Kazuaki, Ryosuke Kawakami, Ryuichi Shigemoto, and Tomomi Nemoto.
    “Super Resolution Structural Analysis of Dendritic Spines Using Three-Dimensional
    Structured Illumination Microscopy in Cleared Mouse Brain Slices.” <i>European
    Journal of Neuroscience</i>. Wiley, 2018. <a href="https://doi.org/10.1111/ejn.13901">https://doi.org/10.1111/ejn.13901</a>.
  ieee: K. Sawada, R. Kawakami, R. Shigemoto, and T. Nemoto, “Super resolution structural
    analysis of dendritic spines using three-dimensional structured illumination microscopy
    in cleared mouse brain slices,” <i>European Journal of Neuroscience</i>, vol.
    47, no. 9. Wiley, pp. 1033–1042, 2018.
  ista: Sawada K, Kawakami R, Shigemoto R, Nemoto T. 2018. Super resolution structural
    analysis of dendritic spines using three-dimensional structured illumination microscopy
    in cleared mouse brain slices. European Journal of Neuroscience. 47(9), 1033–1042.
  mla: Sawada, Kazuaki, et al. “Super Resolution Structural Analysis of Dendritic
    Spines Using Three-Dimensional Structured Illumination Microscopy in Cleared Mouse
    Brain Slices.” <i>European Journal of Neuroscience</i>, vol. 47, no. 9, Wiley,
    2018, pp. 1033–42, doi:<a href="https://doi.org/10.1111/ejn.13901">10.1111/ejn.13901</a>.
  short: K. Sawada, R. Kawakami, R. Shigemoto, T. Nemoto, European Journal of Neuroscience
    47 (2018) 1033–1042.
date_created: 2018-12-11T11:45:50Z
date_published: 2018-03-07T00:00:00Z
date_updated: 2023-09-19T09:58:40Z
day: '07'
ddc:
- '570'
department:
- _id: RySh
doi: 10.1111/ejn.13901
external_id:
  isi:
  - '000431496400001'
file:
- access_level: open_access
  checksum: 98e901d8229e44aa8f3b51d248dedd09
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T16:16:50Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '5721'
  file_name: 2018_EJN_Sawada.pdf
  file_size: 4850261
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
intvolume: '        47'
isi: 1
issue: '9'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1033 - 1042
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley
publist_id: '7539'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Super resolution structural analysis of dendritic spines using three-dimensional
  structured illumination microscopy in cleared mouse brain slices
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 47
year: '2018'
...
---
_id: '327'
abstract:
- lang: eng
  text: Many-body quantum systems typically display fast dynamics and ballistic spreading
    of information. Here we address the open problem of how slow the dynamics can
    be after a generic breaking of integrability by local interactions. We develop
    a method based on degenerate perturbation theory that reveals slow dynamical regimes
    and delocalization processes in general translation invariant models, along with
    accurate estimates of their delocalization time scales. Our results shed light
    on the fundamental questions of the robustness of quantum integrable systems and
    the possibility of many-body localization without disorder. As an example, we
    construct a large class of one-dimensional lattice models where, despite the absence
    of asymptotic localization, the transient dynamics is exceptionally slow, i.e.,
    the dynamics is indistinguishable from that of many-body localized systems for
    the system sizes and time scales accessible in experiments and numerical simulations.
acknowledgement: 'We thank F. Huveneers for useful discussions. Z.P. and A.M. acknowledge
  support by EPSRC Grant No. EP/P009409/1 and and the Royal Society Research Grant
  No. RG160635. Statement of compliance with EPSRC policy framework on research data:
  This publication is theoretical work that does not require supporting research data.
  D.A. acknowledges support by the Swiss National Science Foundation. M.Z., M.M. and
  T.P. acknowledge Grants J1-7279 (M.Z.) and N1-0025 (M.M. and T.P.) of Slovenian
  Research Agency, and Advanced Grant of European Research Council, Grant No. 694544
  - OMNES (T.P.).'
article_number: '104307'
article_processing_charge: No
arxiv: 1
author:
- first_name: Alexios
  full_name: Michailidis, Alexios
  id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
  last_name: Michailidis
  orcid: 0000-0002-8443-1064
- first_name: Marko
  full_name: Žnidarič, Marko
  last_name: Žnidarič
- first_name: Mariya
  full_name: Medvedyeva, Mariya
  last_name: Medvedyeva
- first_name: Dmitry
  full_name: Abanin, Dmitry
  last_name: Abanin
- first_name: Tomaž
  full_name: Prosen, Tomaž
  last_name: Prosen
- first_name: Zlatko
  full_name: Papić, Zlatko
  last_name: Papić
citation:
  ama: Michailidis A, Žnidarič M, Medvedyeva M, Abanin D, Prosen T, Papić Z. Slow
    dynamics in translation-invariant quantum lattice models. <i>Physical Review B</i>.
    2018;97(10). doi:<a href="https://doi.org/10.1103/PhysRevB.97.104307">10.1103/PhysRevB.97.104307</a>
  apa: Michailidis, A., Žnidarič, M., Medvedyeva, M., Abanin, D., Prosen, T., &#38;
    Papić, Z. (2018). Slow dynamics in translation-invariant quantum lattice models.
    <i>Physical Review B</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevB.97.104307">https://doi.org/10.1103/PhysRevB.97.104307</a>
  chicago: Michailidis, Alexios, Marko Žnidarič, Mariya Medvedyeva, Dmitry Abanin,
    Tomaž Prosen, and Zlatko Papić. “Slow Dynamics in Translation-Invariant Quantum
    Lattice Models.” <i>Physical Review B</i>. American Physical Society, 2018. <a
    href="https://doi.org/10.1103/PhysRevB.97.104307">https://doi.org/10.1103/PhysRevB.97.104307</a>.
  ieee: A. Michailidis, M. Žnidarič, M. Medvedyeva, D. Abanin, T. Prosen, and Z. Papić,
    “Slow dynamics in translation-invariant quantum lattice models,” <i>Physical Review
    B</i>, vol. 97, no. 10. American Physical Society, 2018.
  ista: Michailidis A, Žnidarič M, Medvedyeva M, Abanin D, Prosen T, Papić Z. 2018.
    Slow dynamics in translation-invariant quantum lattice models. Physical Review
    B. 97(10), 104307.
  mla: Michailidis, Alexios, et al. “Slow Dynamics in Translation-Invariant Quantum
    Lattice Models.” <i>Physical Review B</i>, vol. 97, no. 10, 104307, American Physical
    Society, 2018, doi:<a href="https://doi.org/10.1103/PhysRevB.97.104307">10.1103/PhysRevB.97.104307</a>.
  short: A. Michailidis, M. Žnidarič, M. Medvedyeva, D. Abanin, T. Prosen, Z. Papić,
    Physical Review B 97 (2018).
date_created: 2018-12-11T11:45:50Z
date_published: 2018-03-19T00:00:00Z
date_updated: 2025-06-04T07:50:22Z
day: '19'
department:
- _id: MaSe
doi: 10.1103/PhysRevB.97.104307
external_id:
  arxiv:
  - '1706.05026'
  isi:
  - '000427798800005'
intvolume: '        97'
isi: 1
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1706.05026
month: '03'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_status: published
publisher: American Physical Society
publist_id: '7538'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Slow dynamics in translation-invariant quantum lattice models
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 97
year: '2018'
...
---
_id: '328'
abstract:
- lang: eng
  text: The drag of turbulent flows can be drastically decreased by adding small amounts
    of high molecular weight polymers. While drag reduction initially increases with
    polymer concentration, it eventually saturates to what is known as the maximum
    drag reduction (MDR) asymptote; this asymptote is generally attributed to the
    dynamics being reduced to a marginal yet persistent state of subdued turbulent
    motion. Contrary to this accepted view, we show that, for an appropriate choice
    of parameters, polymers can reduce the drag beyond the suggested asymptotic limit,
    eliminating turbulence and giving way to laminar flow. At higher polymer concentrations,
    however, the laminar state becomes unstable, resulting in a fluctuating flow with
    the characteristic drag of the MDR asymptote. Our findings indicate that the asymptotic
    state is hence dynamically disconnected from ordinary turbulence. © 2018 American
    Physical Society.
acknowledged_ssus:
- _id: SSU
acknowledgement: The authors thank Philipp Maier and the IST Austria workshop for
  their dedicated technical support.
article_number: '124501'
article_processing_charge: No
arxiv: 1
author:
- first_name: George H
  full_name: Choueiri, George H
  id: 448BD5BC-F248-11E8-B48F-1D18A9856A87
  last_name: Choueiri
- first_name: Jose M
  full_name: Lopez Alonso, Jose M
  id: 40770848-F248-11E8-B48F-1D18A9856A87
  last_name: Lopez Alonso
  orcid: 0000-0002-0384-2022
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Choueiri GH, Lopez Alonso JM, Hof B. Exceeding the asymptotic limit of polymer
    drag reduction. <i>Physical Review Letters</i>. 2018;120(12). doi:<a href="https://doi.org/10.1103/PhysRevLett.120.124501">10.1103/PhysRevLett.120.124501</a>
  apa: Choueiri, G. H., Lopez Alonso, J. M., &#38; Hof, B. (2018). Exceeding the asymptotic
    limit of polymer drag reduction. <i>Physical Review Letters</i>. American Physical
    Society. <a href="https://doi.org/10.1103/PhysRevLett.120.124501">https://doi.org/10.1103/PhysRevLett.120.124501</a>
  chicago: Choueiri, George H, Jose M Lopez Alonso, and Björn Hof. “Exceeding the
    Asymptotic Limit of Polymer Drag Reduction.” <i>Physical Review Letters</i>. American
    Physical Society, 2018. <a href="https://doi.org/10.1103/PhysRevLett.120.124501">https://doi.org/10.1103/PhysRevLett.120.124501</a>.
  ieee: G. H. Choueiri, J. M. Lopez Alonso, and B. Hof, “Exceeding the asymptotic
    limit of polymer drag reduction,” <i>Physical Review Letters</i>, vol. 120, no.
    12. American Physical Society, 2018.
  ista: Choueiri GH, Lopez Alonso JM, Hof B. 2018. Exceeding the asymptotic limit
    of polymer drag reduction. Physical Review Letters. 120(12), 124501.
  mla: Choueiri, George H., et al. “Exceeding the Asymptotic Limit of Polymer Drag
    Reduction.” <i>Physical Review Letters</i>, vol. 120, no. 12, 124501, American
    Physical Society, 2018, doi:<a href="https://doi.org/10.1103/PhysRevLett.120.124501">10.1103/PhysRevLett.120.124501</a>.
  short: G.H. Choueiri, J.M. Lopez Alonso, B. Hof, Physical Review Letters 120 (2018).
corr_author: '1'
date_created: 2018-12-11T11:45:51Z
date_published: 2018-03-19T00:00:00Z
date_updated: 2025-06-04T07:52:00Z
day: '19'
department:
- _id: BjHo
doi: 10.1103/PhysRevLett.120.124501
ec_funded: 1
external_id:
  arxiv:
  - '1703.06271'
  isi:
  - '000427804000005'
intvolume: '       120'
isi: 1
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1703.06271
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 25152F3A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '306589'
  name: Decoding the complexity of turbulence at its origin
publication: Physical Review Letters
publication_status: published
publisher: American Physical Society
publist_id: '7537'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Exceeding the asymptotic limit of polymer drag reduction
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 120
year: '2018'
...
---
_id: '33'
abstract:
- lang: eng
  text: Secondary contact is the reestablishment of gene flow between sister populations
    that have diverged. For instance, at the end of the Quaternary glaciations in
    Europe, secondary contact occurred during the northward expansion of the populations
    which had found refugia in the southern peninsulas. With the advent of multi-locus
    markers, secondary contact can be investigated using various molecular signatures
    including gradients of allele frequency, admixture clines, and local increase
    of genetic differentiation. We use coalescent simulations to investigate if molecular
    data provide enough information to distinguish between secondary contact following
    range expansion and an alternative evolutionary scenario consisting of a barrier
    to gene flow in an isolation-by-distance model. We find that an excess of linkage
    disequilibrium and of genetic diversity at the suture zone is a unique signature
    of secondary contact. We also find that the directionality index ψ, which was
    proposed to study range expansion, is informative to distinguish between the two
    hypotheses. However, although evidence for secondary contact is usually conveyed
    by statistics related to admixture coefficients, we find that they can be confounded
    by isolation-by-distance. We recommend to account for the spatial repartition
    of individuals when investigating secondary contact in order to better reflect
    the complex spatio-temporal evolution of populations and species.
acknowledgement: 'Johanna Bertl was supported by the Vienna Graduate School of Population
  Genetics (Austrian Science Fund (FWF): W1225-B20) and worked on this project while
  employed at the Department of Statistics and Operations Research, University of
  Vienna, Austria. This article was developed in the framework of the Grenoble Alpes
  Data Institute, which is supported by the French National Research Agency under
  the “Investissments d’avenir” program (ANR-15-IDEX-02).'
article_number: e5325
article_processing_charge: No
author:
- first_name: Johanna
  full_name: Bertl, Johanna
  last_name: Bertl
- first_name: Harald
  full_name: Ringbauer, Harald
  id: 417FCFF4-F248-11E8-B48F-1D18A9856A87
  last_name: Ringbauer
  orcid: 0000-0002-4884-9682
- first_name: Michaël
  full_name: Blum, Michaël
  last_name: Blum
citation:
  ama: Bertl J, Ringbauer H, Blum M. Can secondary contact following range expansion
    be distinguished from barriers to gene flow? <i>PeerJ</i>. 2018;2018(10). doi:<a
    href="https://doi.org/10.7717/peerj.5325">10.7717/peerj.5325</a>
  apa: Bertl, J., Ringbauer, H., &#38; Blum, M. (2018). Can secondary contact following
    range expansion be distinguished from barriers to gene flow? <i>PeerJ</i>. PeerJ.
    <a href="https://doi.org/10.7717/peerj.5325">https://doi.org/10.7717/peerj.5325</a>
  chicago: Bertl, Johanna, Harald Ringbauer, and Michaël Blum. “Can Secondary Contact
    Following Range Expansion Be Distinguished from Barriers to Gene Flow?” <i>PeerJ</i>.
    PeerJ, 2018. <a href="https://doi.org/10.7717/peerj.5325">https://doi.org/10.7717/peerj.5325</a>.
  ieee: J. Bertl, H. Ringbauer, and M. Blum, “Can secondary contact following range
    expansion be distinguished from barriers to gene flow?,” <i>PeerJ</i>, vol. 2018,
    no. 10. PeerJ, 2018.
  ista: Bertl J, Ringbauer H, Blum M. 2018. Can secondary contact following range
    expansion be distinguished from barriers to gene flow? PeerJ. 2018(10), e5325.
  mla: Bertl, Johanna, et al. “Can Secondary Contact Following Range Expansion Be
    Distinguished from Barriers to Gene Flow?” <i>PeerJ</i>, vol. 2018, no. 10, e5325,
    PeerJ, 2018, doi:<a href="https://doi.org/10.7717/peerj.5325">10.7717/peerj.5325</a>.
  short: J. Bertl, H. Ringbauer, M. Blum, PeerJ 2018 (2018).
date_created: 2018-12-11T11:44:16Z
date_published: 2018-10-01T00:00:00Z
date_updated: 2023-10-17T12:24:43Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.7717/peerj.5325
external_id:
  isi:
  - '000447204400001'
  pmid:
  - '30294507'
file:
- access_level: open_access
  checksum: 3334886c4b39678db4c4b74299ca14ba
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T10:46:06Z
  date_updated: 2020-07-14T12:46:06Z
  file_id: '5692'
  file_name: 2018_PeerJ_Bertl.pdf
  file_size: 1328344
  relation: main_file
file_date_updated: 2020-07-14T12:46:06Z
has_accepted_license: '1'
intvolume: '      2018'
isi: 1
issue: '10'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: PeerJ
publication_status: published
publisher: PeerJ
publist_id: '8022'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Can secondary contact following range expansion be distinguished from barriers
  to gene flow?
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2018
year: '2018'
...
---
_id: '3300'
abstract:
- lang: eng
  text: "This book first explores the origins of this idea, grounded in theoretical
    work on temporal logic and automata. The editors and authors are among the world's
    leading researchers in this domain, and they contributed 32 chapters representing
    a thorough view of the development and application of the technique. Topics covered
    include binary decision diagrams, symbolic model checking, satisfiability modulo
    theories, partial-order reduction, abstraction, interpolation, concurrency, security
    protocols, games, probabilistic model checking, and process algebra, and chapters
    on the transfer of theory to industrial practice, property specification languages
    for hardware, and verification of real-time systems and hybrid systems.\r\n\r\nThe
    book will be valuable for researchers and graduate students engaged with the development
    of formal methods and verification tools."
article_processing_charge: No
author:
- first_name: Edmund M.
  full_name: Clarke, Edmund M.
  last_name: Clarke
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Helmut
  full_name: Veith, Helmut
  last_name: Veith
- first_name: Roderick
  full_name: Bloem, Roderick
  last_name: Bloem
citation:
  ama: 'Clarke EM, Henzinger TA, Veith H, Bloem R. <i>Handbook of Model Checking</i>.
    1st ed. Cham: Springer Nature; 2018. doi:<a href="https://doi.org/10.1007/978-3-319-10575-8">10.1007/978-3-319-10575-8</a>'
  apa: 'Clarke, E. M., Henzinger, T. A., Veith, H., &#38; Bloem, R. (2018). <i>Handbook
    of Model Checking</i> (1st ed.). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-319-10575-8">https://doi.org/10.1007/978-3-319-10575-8</a>'
  chicago: 'Clarke, Edmund M., Thomas A Henzinger, Helmut Veith, and Roderick Bloem.
    <i>Handbook of Model Checking</i>. 1st ed. Cham: Springer Nature, 2018. <a href="https://doi.org/10.1007/978-3-319-10575-8">https://doi.org/10.1007/978-3-319-10575-8</a>.'
  ieee: 'E. M. Clarke, T. A. Henzinger, H. Veith, and R. Bloem, <i>Handbook of Model
    Checking</i>, 1st ed. Cham: Springer Nature, 2018.'
  ista: 'Clarke EM, Henzinger TA, Veith H, Bloem R. 2018. Handbook of Model Checking
    1st ed., Cham: Springer Nature, XLVIII, 1212p.'
  mla: Clarke, Edmund M., et al. <i>Handbook of Model Checking</i>. 1st ed., Springer
    Nature, 2018, doi:<a href="https://doi.org/10.1007/978-3-319-10575-8">10.1007/978-3-319-10575-8</a>.
  short: E.M. Clarke, T.A. Henzinger, H. Veith, R. Bloem, Handbook of Model Checking,
    1st ed., Springer Nature, Cham, 2018.
date_created: 2018-12-11T12:02:32Z
date_published: 2018-06-08T00:00:00Z
date_updated: 2021-12-21T10:49:36Z
day: '08'
department:
- _id: ToHe
doi: 10.1007/978-3-319-10575-8
edition: '1'
language:
- iso: eng
month: '06'
oa_version: None
page: XLVIII, 1212
place: Cham
publication_identifier:
  eisbn:
  - 978-3-319-10575-8
  isbn:
  - 978-3-319-10574-1
publication_status: published
publisher: Springer Nature
publist_id: '3340'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Handbook of Model Checking
type: book
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2018'
...
---
_id: '34'
abstract:
- lang: eng
  text: Partially observable Markov decision processes (POMDPs) are widely used in
    probabilistic planning problems in which an agent interacts with an environment
    using noisy and imprecise sensors. We study a setting in which the sensors are
    only partially defined and the goal is to synthesize “weakest” additional sensors,
    such that in the resulting POMDP, there is a small-memory policy for the agent
    that almost-surely (with probability 1) satisfies a reachability objective. We
    show that the problem is NP-complete, and present a symbolic algorithm by encoding
    the problem into SAT instances. We illustrate trade-offs between the amount of
    memory of the policy and the number of additional sensors on a simple example.
    We have implemented our approach and consider three classical POMDP examples from
    the literature, and show that in all the examples the number of sensors can be
    significantly decreased (as compared to the existing solutions in the literature)
    without increasing the complexity of the policies.
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Chemlík, Martin
  last_name: Chemlík
- first_name: Ufuk
  full_name: Topcu, Ufuk
  last_name: Topcu
citation:
  ama: 'Chatterjee K, Chemlík M, Topcu U. Sensor synthesis for POMDPs with reachability
    objectives. In: <i>28th International Conference on Automated Planning and Scheduling</i>.
    Vol 2018. AAAI Press; 2018:47-55. doi:<a href="https://doi.org/10.1609/icaps.v28i1.13875">10.1609/icaps.v28i1.13875</a>'
  apa: 'Chatterjee, K., Chemlík, M., &#38; Topcu, U. (2018). Sensor synthesis for
    POMDPs with reachability objectives. In <i>28th International Conference on Automated
    Planning and Scheduling</i> (Vol. 2018, pp. 47–55). Delft, Netherlands: AAAI Press.
    <a href="https://doi.org/10.1609/icaps.v28i1.13875">https://doi.org/10.1609/icaps.v28i1.13875</a>'
  chicago: Chatterjee, Krishnendu, Martin Chemlík, and Ufuk Topcu. “Sensor Synthesis
    for POMDPs with Reachability Objectives.” In <i>28th International Conference
    on Automated Planning and Scheduling</i>, 2018:47–55. AAAI Press, 2018. <a href="https://doi.org/10.1609/icaps.v28i1.13875">https://doi.org/10.1609/icaps.v28i1.13875</a>.
  ieee: K. Chatterjee, M. Chemlík, and U. Topcu, “Sensor synthesis for POMDPs with
    reachability objectives,” in <i>28th International Conference on Automated Planning
    and Scheduling</i>, Delft, Netherlands, 2018, vol. 2018, pp. 47–55.
  ista: 'Chatterjee K, Chemlík M, Topcu U. 2018. Sensor synthesis for POMDPs with
    reachability objectives. 28th International Conference on Automated Planning and
    Scheduling. ICAPS: International Conference on Automated Planning and Scheduling
    vol. 2018, 47–55.'
  mla: Chatterjee, Krishnendu, et al. “Sensor Synthesis for POMDPs with Reachability
    Objectives.” <i>28th International Conference on Automated Planning and Scheduling</i>,
    vol. 2018, AAAI Press, 2018, pp. 47–55, doi:<a href="https://doi.org/10.1609/icaps.v28i1.13875">10.1609/icaps.v28i1.13875</a>.
  short: K. Chatterjee, M. Chemlík, U. Topcu, in:, 28th International Conference on
    Automated Planning and Scheduling, AAAI Press, 2018, pp. 47–55.
conference:
  end_date: 2018-06-29
  location: Delft, Netherlands
  name: 'ICAPS: International Conference on Automated Planning and Scheduling'
  start_date: 2018-06-24
date_created: 2018-12-11T11:44:16Z
date_published: 2018-06-01T00:00:00Z
date_updated: 2025-04-15T07:23:29Z
day: '01'
department:
- _id: KrCh
doi: 10.1609/icaps.v28i1.13875
ec_funded: 1
external_id:
  arxiv:
  - '1710.00675'
  isi:
  - '000492986200006'
intvolume: '      2018'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1710.00675
month: '06'
oa: 1
oa_version: Preprint
page: 47 - 55
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication: 28th International Conference on Automated Planning and Scheduling
publication_status: published
publisher: AAAI Press
publist_id: '8021'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sensor synthesis for POMDPs with reachability objectives
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2018
year: '2018'
...
---
_id: '134'
abstract:
- lang: eng
  text: "The current state of the art in real-time two-dimensional water wave simulation
    requires developers to choose between efficient Fourier-based methods, which lack
    interactions with moving obstacles, and finite-difference or finite element methods,
    which handle environmental interactions but are significantly more expensive.
    This paper attempts to bridge this long-standing gap between complexity and performance,
    by proposing a new wave simulation method that can faithfully simulate wave interactions
    with moving obstacles in real time while simultaneously preserving minute details
    and accommodating very large simulation domains.\r\n\r\nPrevious methods for simulating
    2D water waves directly compute the change in height of the water surface, a strategy
    which imposes limitations based on the CFL condition (fast moving waves require
    small time steps) and Nyquist's limit (small wave details require closely-spaced
    simulation variables). This paper proposes a novel wavelet transformation that
    discretizes the liquid motion in terms of amplitude-like functions that vary over
    space, frequency, and direction, effectively generalizing Fourier-based methods
    to handle local interactions. Because these new variables change much more slowly
    over space than the original water height function, our change of variables drastically
    reduces the limitations of the CFL condition and Nyquist limit, allowing us to
    simulate highly detailed water waves at very large visual resolutions. Our discretization
    is amenable to fast summation and easy to parallelize. We also present basic extensions
    like pre-computed wave paths and two-way solid fluid coupling. Finally, we argue
    that our discretization provides a convenient set of variables for artistic manipulation,
    which we illustrate with a novel wave-painting interface."
acknowledged_ssus:
- _id: ScienComp
alternative_title:
- SIGGRAPH
article_number: '94'
article_processing_charge: No
author:
- first_name: Stefan
  full_name: Jeschke, Stefan
  id: 44D6411A-F248-11E8-B48F-1D18A9856A87
  last_name: Jeschke
- first_name: Tomas
  full_name: Skrivan, Tomas
  id: 486A5A46-F248-11E8-B48F-1D18A9856A87
  last_name: Skrivan
- first_name: Matthias
  full_name: Mueller Fischer, Matthias
  last_name: Mueller Fischer
- first_name: Nuttapong
  full_name: Chentanez, Nuttapong
  last_name: Chentanez
- first_name: Miles
  full_name: Macklin, Miles
  last_name: Macklin
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Jeschke S, Skrivan T, Mueller Fischer M, Chentanez N, Macklin M, Wojtan C.
    Water surface wavelets. <i>ACM Transactions on Graphics</i>. 2018;37(4). doi:<a
    href="https://doi.org/10.1145/3197517.3201336">10.1145/3197517.3201336</a>
  apa: Jeschke, S., Skrivan, T., Mueller Fischer, M., Chentanez, N., Macklin, M.,
    &#38; Wojtan, C. (2018). Water surface wavelets. <i>ACM Transactions on Graphics</i>.
    ACM. <a href="https://doi.org/10.1145/3197517.3201336">https://doi.org/10.1145/3197517.3201336</a>
  chicago: Jeschke, Stefan, Tomas Skrivan, Matthias Mueller Fischer, Nuttapong Chentanez,
    Miles Macklin, and Chris Wojtan. “Water Surface Wavelets.” <i>ACM Transactions
    on Graphics</i>. ACM, 2018. <a href="https://doi.org/10.1145/3197517.3201336">https://doi.org/10.1145/3197517.3201336</a>.
  ieee: S. Jeschke, T. Skrivan, M. Mueller Fischer, N. Chentanez, M. Macklin, and
    C. Wojtan, “Water surface wavelets,” <i>ACM Transactions on Graphics</i>, vol.
    37, no. 4. ACM, 2018.
  ista: Jeschke S, Skrivan T, Mueller Fischer M, Chentanez N, Macklin M, Wojtan C.
    2018. Water surface wavelets. ACM Transactions on Graphics. 37(4), 94.
  mla: Jeschke, Stefan, et al. “Water Surface Wavelets.” <i>ACM Transactions on Graphics</i>,
    vol. 37, no. 4, 94, ACM, 2018, doi:<a href="https://doi.org/10.1145/3197517.3201336">10.1145/3197517.3201336</a>.
  short: S. Jeschke, T. Skrivan, M. Mueller Fischer, N. Chentanez, M. Macklin, C.
    Wojtan, ACM Transactions on Graphics 37 (2018).
date_created: 2018-12-11T11:44:48Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2024-10-22T09:58:20Z
day: '30'
ddc:
- '000'
department:
- _id: ChWo
doi: 10.1145/3197517.3201336
ec_funded: 1
external_id:
  isi:
  - '000448185000055'
file:
- access_level: open_access
  checksum: db75ebabe2ec432bf41389e614d6ef62
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T09:59:23Z
  date_updated: 2020-07-14T12:44:45Z
  file_id: '5744'
  file_name: 2018_ACM_Jeschke.pdf
  file_size: 22185016
  relation: main_file
file_date_updated: 2020-07-14T12:44:45Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '4'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '638176'
  name: 'Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large
    Scales'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: ACM Transactions on Graphics
publication_status: published
publisher: ACM
publist_id: '7789'
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/new-water-simulation-captures-small-details-even-in-large-scenes/
scopus_import: '1'
status: public
title: Water surface wavelets
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: journal_article
user_id: 2EBD1598-F248-11E8-B48F-1D18A9856A87
volume: 37
year: '2018'
...
---
_id: '135'
abstract:
- lang: eng
  text: The Fluid Implicit Particle method (FLIP) reduces numerical dissipation by
    combining particles with grids. To improve performance, the subsequent narrow
    band FLIP method (NB‐FLIP) uses a FLIP‐based fluid simulation only near the liquid
    surface and a traditional grid‐based fluid simulation away from the surface. This
    spatially‐limited FLIP simulation significantly reduces the number of particles
    and alleviates a computational bottleneck. In this paper, we extend the NB‐FLIP
    idea even further, by allowing a simulation to transition between a FLIP‐like
    fluid simulation and a grid‐based simulation in arbitrary locations, not just
    near the surface. This approach leads to even more savings in memory and computation,
    because we can concentrate the particles only in areas where they are needed.
    More importantly, this new method allows us to seamlessly transition to smooth
    implicit surface geometry wherever the particle‐based simulation is unnecessary.
    Consequently, our method leads to a practical algorithm for avoiding the noisy
    surface artifacts associated with particle‐based liquid simulations, while simultaneously
    maintaining the benefits of a FLIP simulation in regions of dynamic motion.
alternative_title:
- Eurographics
article_processing_charge: No
article_type: original
author:
- first_name: Takahiro
  full_name: Sato, Takahiro
  last_name: Sato
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Nils
  full_name: Thuerey, Nils
  last_name: Thuerey
- first_name: Takeo
  full_name: Igarashi, Takeo
  last_name: Igarashi
- first_name: Ryoichi
  full_name: Ando, Ryoichi
  last_name: Ando
citation:
  ama: Sato T, Wojtan C, Thuerey N, Igarashi T, Ando R. Extended narrow band FLIP
    for liquid simulations. <i>Computer Graphics Forum</i>. 2018;37(2):169-177. doi:<a
    href="https://doi.org/10.1111/cgf.13351">10.1111/cgf.13351</a>
  apa: Sato, T., Wojtan, C., Thuerey, N., Igarashi, T., &#38; Ando, R. (2018). Extended
    narrow band FLIP for liquid simulations. <i>Computer Graphics Forum</i>. Wiley.
    <a href="https://doi.org/10.1111/cgf.13351">https://doi.org/10.1111/cgf.13351</a>
  chicago: Sato, Takahiro, Chris Wojtan, Nils Thuerey, Takeo Igarashi, and Ryoichi
    Ando. “Extended Narrow Band FLIP for Liquid Simulations.” <i>Computer Graphics
    Forum</i>. Wiley, 2018. <a href="https://doi.org/10.1111/cgf.13351">https://doi.org/10.1111/cgf.13351</a>.
  ieee: T. Sato, C. Wojtan, N. Thuerey, T. Igarashi, and R. Ando, “Extended narrow
    band FLIP for liquid simulations,” <i>Computer Graphics Forum</i>, vol. 37, no.
    2. Wiley, pp. 169–177, 2018.
  ista: Sato T, Wojtan C, Thuerey N, Igarashi T, Ando R. 2018. Extended narrow band
    FLIP for liquid simulations. Computer Graphics Forum. 37(2), 169–177.
  mla: Sato, Takahiro, et al. “Extended Narrow Band FLIP for Liquid Simulations.”
    <i>Computer Graphics Forum</i>, vol. 37, no. 2, Wiley, 2018, pp. 169–77, doi:<a
    href="https://doi.org/10.1111/cgf.13351">10.1111/cgf.13351</a>.
  short: T. Sato, C. Wojtan, N. Thuerey, T. Igarashi, R. Ando, Computer Graphics Forum
    37 (2018) 169–177.
date_created: 2018-12-11T11:44:49Z
date_published: 2018-05-22T00:00:00Z
date_updated: 2024-10-22T09:58:20Z
day: '22'
ddc:
- '006'
department:
- _id: ChWo
doi: 10.1111/cgf.13351
ec_funded: 1
external_id:
  isi:
  - '000434085600016'
file:
- access_level: open_access
  checksum: 8edb90da8a72395eb5d970580e0925b6
  content_type: application/pdf
  creator: wojtan
  date_created: 2020-10-08T08:38:23Z
  date_updated: 2020-10-08T08:38:23Z
  file_id: '8627'
  file_name: exnbflip.pdf
  file_size: 54309947
  relation: main_file
  success: 1
file_date_updated: 2020-10-08T08:38:23Z
has_accepted_license: '1'
intvolume: '        37'
isi: 1
issue: '2'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 169 - 177
project:
- _id: 2533E772-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '638176'
  name: 'Big Splash: Efficient Simulation of Natural Phenomena at Extremely Large
    Scales'
publication: Computer Graphics Forum
publication_identifier:
  issn:
  - 0167-7055
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extended narrow band FLIP for liquid simulations
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 37
year: '2018'
...
---
_id: '136'
abstract:
- lang: eng
  text: Recent studies suggest that unstable, nonchaotic solutions of the Navier-Stokes
    equation may provide deep insights into fluid turbulence. In this article, we
    present a combined experimental and numerical study exploring the dynamical role
    of unstable equilibrium solutions and their invariant manifolds in a weakly turbulent,
    electromagnetically driven, shallow fluid layer. Identifying instants when turbulent
    evolution slows down, we compute 31 unstable equilibria of a realistic two-dimensional
    model of the flow. We establish the dynamical relevance of these unstable equilibria
    by showing that they are closely visited by the turbulent flow. We also establish
    the dynamical relevance of unstable manifolds by verifying that they are shadowed
    by turbulent trajectories departing from the neighborhoods of unstable equilibria
    over large distances in state space.
article_processing_charge: No
arxiv: 1
author:
- first_name: Balachandra
  full_name: Suri, Balachandra
  id: 47A5E706-F248-11E8-B48F-1D18A9856A87
  last_name: Suri
- first_name: Jeffrey
  full_name: Tithof, Jeffrey
  last_name: Tithof
- first_name: Roman
  full_name: Grigoriev, Roman
  last_name: Grigoriev
- first_name: Michael
  full_name: Schatz, Michael
  last_name: Schatz
citation:
  ama: Suri B, Tithof J, Grigoriev R, Schatz M. Unstable equilibria and invariant
    manifolds in quasi-two-dimensional Kolmogorov-like flow. <i>Physical Review E</i>.
    2018;98(2). doi:<a href="https://doi.org/10.1103/PhysRevE.98.023105">10.1103/PhysRevE.98.023105</a>
  apa: Suri, B., Tithof, J., Grigoriev, R., &#38; Schatz, M. (2018). Unstable equilibria
    and invariant manifolds in quasi-two-dimensional Kolmogorov-like flow. <i>Physical
    Review E</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevE.98.023105">https://doi.org/10.1103/PhysRevE.98.023105</a>
  chicago: Suri, Balachandra, Jeffrey Tithof, Roman Grigoriev, and Michael Schatz.
    “Unstable Equilibria and Invariant Manifolds in Quasi-Two-Dimensional Kolmogorov-like
    Flow.” <i>Physical Review E</i>. American Physical Society, 2018. <a href="https://doi.org/10.1103/PhysRevE.98.023105">https://doi.org/10.1103/PhysRevE.98.023105</a>.
  ieee: B. Suri, J. Tithof, R. Grigoriev, and M. Schatz, “Unstable equilibria and
    invariant manifolds in quasi-two-dimensional Kolmogorov-like flow,” <i>Physical
    Review E</i>, vol. 98, no. 2. American Physical Society, 2018.
  ista: Suri B, Tithof J, Grigoriev R, Schatz M. 2018. Unstable equilibria and invariant
    manifolds in quasi-two-dimensional Kolmogorov-like flow. Physical Review E. 98(2).
  mla: Suri, Balachandra, et al. “Unstable Equilibria and Invariant Manifolds in Quasi-Two-Dimensional
    Kolmogorov-like Flow.” <i>Physical Review E</i>, vol. 98, no. 2, American Physical
    Society, 2018, doi:<a href="https://doi.org/10.1103/PhysRevE.98.023105">10.1103/PhysRevE.98.023105</a>.
  short: B. Suri, J. Tithof, R. Grigoriev, M. Schatz, Physical Review E 98 (2018).
date_created: 2018-12-11T11:44:49Z
date_published: 2018-08-13T00:00:00Z
date_updated: 2023-10-10T13:29:10Z
day: '13'
department:
- _id: BjHo
doi: 10.1103/PhysRevE.98.023105
external_id:
  arxiv:
  - '1808.02088'
  isi:
  - '000441466800010'
intvolume: '        98'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1808.02088
month: '08'
oa: 1
oa_version: Submitted Version
publication: Physical Review E
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Unstable equilibria and invariant manifolds in quasi-two-dimensional Kolmogorov-like
  flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 98
year: '2018'
...
---
_id: '137'
abstract:
- lang: eng
  text: Fluorescent sensors are an essential part of the experimental toolbox of the
    life sciences, where they are used ubiquitously to visualize intra- and extracellular
    signaling. In the brain, optical neurotransmitter sensors can shed light on temporal
    and spatial aspects of signal transmission by directly observing, for instance,
    neurotransmitter release and spread. Here we report the development and application
    of the first optical sensor for the amino acid glycine, which is both an inhibitory
    neurotransmitter and a co-agonist of the N-methyl-d-aspartate receptors (NMDARs)
    involved in synaptic plasticity. Computational design of a glycine-specific binding
    protein allowed us to produce the optical glycine FRET sensor (GlyFS), which can
    be used with single and two-photon excitation fluorescence microscopy. We took
    advantage of this newly developed sensor to test predictions about the uneven
    spatial distribution of glycine in extracellular space and to demonstrate that
    extracellular glycine levels are controlled by plasticity-inducing stimuli.
article_processing_charge: No
article_type: original
author:
- first_name: William
  full_name: Zhang, William
  last_name: Zhang
- first_name: Michel
  full_name: Herde, Michel
  last_name: Herde
- first_name: Joshua
  full_name: Mitchell, Joshua
  last_name: Mitchell
- first_name: Jason
  full_name: Whitfield, Jason
  last_name: Whitfield
- first_name: Andreas
  full_name: Wulff, Andreas
  last_name: Wulff
- first_name: Vanessa
  full_name: Vongsouthi, Vanessa
  last_name: Vongsouthi
- first_name: Inmaculada
  full_name: Sanchez Romero, Inmaculada
  id: 3D9C5D30-F248-11E8-B48F-1D18A9856A87
  last_name: Sanchez Romero
- first_name: Polina
  full_name: Gulakova, Polina
  last_name: Gulakova
- first_name: Daniel
  full_name: Minge, Daniel
  last_name: Minge
- first_name: Björn
  full_name: Breithausen, Björn
  last_name: Breithausen
- first_name: Susanne
  full_name: Schoch, Susanne
  last_name: Schoch
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
- first_name: Colin
  full_name: Jackson, Colin
  last_name: Jackson
- first_name: Christian
  full_name: Henneberger, Christian
  last_name: Henneberger
citation:
  ama: Zhang W, Herde M, Mitchell J, et al. Monitoring hippocampal glycine with the
    computationally designed optical sensor GlyFS. <i>Nature Chemical Biology</i>.
    2018;14(9):861-869. doi:<a href="https://doi.org/10.1038/s41589-018-0108-2">10.1038/s41589-018-0108-2</a>
  apa: Zhang, W., Herde, M., Mitchell, J., Whitfield, J., Wulff, A., Vongsouthi, V.,
    … Henneberger, C. (2018). Monitoring hippocampal glycine with the computationally
    designed optical sensor GlyFS. <i>Nature Chemical Biology</i>. Nature Publishing
    Group. <a href="https://doi.org/10.1038/s41589-018-0108-2">https://doi.org/10.1038/s41589-018-0108-2</a>
  chicago: Zhang, William, Michel Herde, Joshua Mitchell, Jason Whitfield, Andreas
    Wulff, Vanessa Vongsouthi, Inmaculada Sanchez-Romero, et al. “Monitoring Hippocampal
    Glycine with the Computationally Designed Optical Sensor GlyFS.” <i>Nature Chemical
    Biology</i>. Nature Publishing Group, 2018. <a href="https://doi.org/10.1038/s41589-018-0108-2">https://doi.org/10.1038/s41589-018-0108-2</a>.
  ieee: W. Zhang <i>et al.</i>, “Monitoring hippocampal glycine with the computationally
    designed optical sensor GlyFS,” <i>Nature Chemical Biology</i>, vol. 14, no. 9.
    Nature Publishing Group, pp. 861–869, 2018.
  ista: Zhang W, Herde M, Mitchell J, Whitfield J, Wulff A, Vongsouthi V, Sanchez-Romero
    I, Gulakova P, Minge D, Breithausen B, Schoch S, Janovjak HL, Jackson C, Henneberger
    C. 2018. Monitoring hippocampal glycine with the computationally designed optical
    sensor GlyFS. Nature Chemical Biology. 14(9), 861–869.
  mla: Zhang, William, et al. “Monitoring Hippocampal Glycine with the Computationally
    Designed Optical Sensor GlyFS.” <i>Nature Chemical Biology</i>, vol. 14, no. 9,
    Nature Publishing Group, 2018, pp. 861–69, doi:<a href="https://doi.org/10.1038/s41589-018-0108-2">10.1038/s41589-018-0108-2</a>.
  short: W. Zhang, M. Herde, J. Mitchell, J. Whitfield, A. Wulff, V. Vongsouthi, I.
    Sanchez-Romero, P. Gulakova, D. Minge, B. Breithausen, S. Schoch, H.L. Janovjak,
    C. Jackson, C. Henneberger, Nature Chemical Biology 14 (2018) 861–869.
date_created: 2018-12-11T11:44:49Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2025-04-15T06:43:11Z
day: '30'
department:
- _id: HaJa
doi: 10.1038/s41589-018-0108-2
external_id:
  isi:
  - '000442174500013'
  pmid:
  - '30061718 '
intvolume: '        14'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pubmed/30061718
month: '07'
oa: 1
oa_version: Submitted Version
page: 861 - 869
pmid: 1
project:
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
  grant_number: RGY0084/2012
  name: In situ real-time imaging of neurotransmitter signaling using designer optical
    sensors
publication: Nature Chemical Biology
publication_status: published
publisher: Nature Publishing Group
publist_id: '7786'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Monitoring hippocampal glycine with the computationally designed optical sensor
  GlyFS
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 14
year: '2018'
...
---
_id: '139'
abstract:
- lang: eng
  text: 'Genome-scale diversity data are increasingly available in a variety of biological
    systems, and can be used to reconstruct the past evolutionary history of species
    divergence. However, extracting the full demographic information from these data
    is not trivial, and requires inferential methods that account for the diversity
    of coalescent histories throughout the genome. Here, we evaluate the potential
    and limitations of one such approach. We reexamine a well-known system of mussel
    sister species, using the joint site frequency spectrum (jSFS) of synonymousmutations
    computed either fromexome capture or RNA-seq, in an Approximate Bayesian Computation
    (ABC) framework. We first assess the best sampling strategy (number of: individuals,
    loci, and bins in the jSFS), and show that model selection is robust to variation
    in the number of individuals and loci. In contrast, different binning choices
    when summarizing the jSFS, strongly affect the results: including classes of low
    and high frequency shared polymorphisms can more effectively reveal recent migration
    events. We then take advantage of the flexibility of ABC to compare more realistic
    models of speciation, including variation in migration rates through time (i.e.,
    periodic connectivity) and across genes (i.e., genome-wide heterogeneity in migration
    rates). We show that these models were consistently selected as the most probable,
    suggesting that mussels have experienced a complex history of gene flow during
    divergence and that the species boundary is semi-permeable. Our work provides
    a comprehensive evaluation of ABC demographic inference in mussels based on the
    coding jSFS, and supplies guidelines for employing different sequencing techniques
    and sampling strategies. We emphasize, perhaps surprisingly, that inferences are
    less limited by the volume of data, than by the way in which they are analyzed.'
article_number: '30083438'
article_processing_charge: No
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Camille
  full_name: Roux, Camille
  last_name: Roux
- first_name: Pierre
  full_name: Gagnaire, Pierre
  last_name: Gagnaire
- first_name: Jonathan
  full_name: Romiguier, Jonathan
  last_name: Romiguier
- first_name: Nicolas
  full_name: Faivre, Nicolas
  last_name: Faivre
- first_name: John
  full_name: Welch, John
  last_name: Welch
- first_name: Nicolas
  full_name: Bierne, Nicolas
  last_name: Bierne
citation:
  ama: 'Fraisse C, Roux C, Gagnaire P, et al. The divergence history of European blue
    mussel species reconstructed from Approximate Bayesian Computation: The effects
    of sequencing techniques and sampling strategies. <i>PeerJ</i>. 2018;2018(7).
    doi:<a href="https://doi.org/10.7717/peerj.5198">10.7717/peerj.5198</a>'
  apa: 'Fraisse, C., Roux, C., Gagnaire, P., Romiguier, J., Faivre, N., Welch, J.,
    &#38; Bierne, N. (2018). The divergence history of European blue mussel species
    reconstructed from Approximate Bayesian Computation: The effects of sequencing
    techniques and sampling strategies. <i>PeerJ</i>. PeerJ. <a href="https://doi.org/10.7717/peerj.5198">https://doi.org/10.7717/peerj.5198</a>'
  chicago: 'Fraisse, Christelle, Camille Roux, Pierre Gagnaire, Jonathan Romiguier,
    Nicolas Faivre, John Welch, and Nicolas Bierne. “The Divergence History of European
    Blue Mussel Species Reconstructed from Approximate Bayesian Computation: The Effects
    of Sequencing Techniques and Sampling Strategies.” <i>PeerJ</i>. PeerJ, 2018.
    <a href="https://doi.org/10.7717/peerj.5198">https://doi.org/10.7717/peerj.5198</a>.'
  ieee: 'C. Fraisse <i>et al.</i>, “The divergence history of European blue mussel
    species reconstructed from Approximate Bayesian Computation: The effects of sequencing
    techniques and sampling strategies,” <i>PeerJ</i>, vol. 2018, no. 7. PeerJ, 2018.'
  ista: 'Fraisse C, Roux C, Gagnaire P, Romiguier J, Faivre N, Welch J, Bierne N.
    2018. The divergence history of European blue mussel species reconstructed from
    Approximate Bayesian Computation: The effects of sequencing techniques and sampling
    strategies. PeerJ. 2018(7), 30083438.'
  mla: 'Fraisse, Christelle, et al. “The Divergence History of European Blue Mussel
    Species Reconstructed from Approximate Bayesian Computation: The Effects of Sequencing
    Techniques and Sampling Strategies.” <i>PeerJ</i>, vol. 2018, no. 7, 30083438,
    PeerJ, 2018, doi:<a href="https://doi.org/10.7717/peerj.5198">10.7717/peerj.5198</a>.'
  short: C. Fraisse, C. Roux, P. Gagnaire, J. Romiguier, N. Faivre, J. Welch, N. Bierne,
    PeerJ 2018 (2018).
date_created: 2018-12-11T11:44:50Z
date_published: 2018-07-30T00:00:00Z
date_updated: 2023-10-17T12:25:28Z
day: '30'
ddc:
- '576'
department:
- _id: BeVi
- _id: NiBa
doi: 10.7717/peerj.5198
external_id:
  isi:
  - '000440484800002'
file:
- access_level: open_access
  checksum: 7d55ae22598a1c70759cd671600cff53
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T09:42:11Z
  date_updated: 2020-07-14T12:44:48Z
  file_id: '5739'
  file_name: 2018_PeerJ_Fraisse.pdf
  file_size: 1480792
  relation: main_file
file_date_updated: 2020-07-14T12:44:48Z
has_accepted_license: '1'
intvolume: '      2018'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: PeerJ
publication_status: published
publisher: PeerJ
publist_id: '7784'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The divergence history of European blue mussel species reconstructed from
  Approximate Bayesian Computation: The effects of sequencing techniques and sampling
  strategies'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2018
year: '2018'
...
---
_id: '14'
abstract:
- lang: eng
  text: The intercellular transport of auxin is driven by PIN-formed (PIN) auxin efflux
    carriers. PINs are localized at the plasma membrane (PM) and on constitutively
    recycling endomembrane vesicles. Therefore, PINs can mediate auxin transport either
    by direct translocation across the PM or by pumping auxin into secretory vesicles
    (SVs), leading to its secretory release upon fusion with the PM. Which of these
    two mechanisms dominates is a matter of debate. Here, we addressed the issue with
    a mathematical modeling approach. We demonstrate that the efficiency of secretory
    transport depends on SV size, half-life of PINs on the PM, pH, exocytosis frequency
    and PIN density. 3D structured illumination microscopy (SIM) was used to determine
    PIN density on the PM. Combining this data with published values of the other
    parameters, we show that the transport activity of PINs in SVs would have to be
    at least 1000× greater than on the PM in order to produce a comparable macroscopic
    auxin transport. If both transport mechanisms operated simultaneously and PINs
    were equally active on SVs and PM, the contribution of secretion to the total
    auxin flux would be negligible. In conclusion, while secretory vesicle-mediated
    transport of auxin is an intriguing and theoretically possible model, it is unlikely
    to be a major mechanism of auxin transport inplanta.
acknowledgement: 'European Research Council (ERC): 742985 to Jiri Friml; M.A. was
  supported by the Austrian Science Fund (FWF) (M2379-B28); AJ was supported by the
  Austria Science Fund (FWF): I03630 to Jiri Friml.'
article_processing_charge: No
article_type: original
author:
- first_name: Sander
  full_name: Hille, Sander
  last_name: Hille
- first_name: Maria
  full_name: Akhmanova, Maria
  id: 3425EC26-F248-11E8-B48F-1D18A9856A87
  last_name: Akhmanova
  orcid: 0000-0003-1522-3162
- first_name: Matous
  full_name: Glanc, Matous
  id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
  last_name: Glanc
  orcid: 0000-0003-0619-7783
- first_name: Alexander J
  full_name: Johnson, Alexander J
  id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
  last_name: Johnson
  orcid: 0000-0002-2739-8843
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Hille S, Akhmanova M, Glanc M, Johnson AJ, Friml J. Relative contribution
    of PIN-containing secretory vesicles and plasma membrane PINs to the directed
    auxin transport: Theoretical estimation. <i>International Journal of Molecular
    Sciences</i>. 2018;19(11). doi:<a href="https://doi.org/10.3390/ijms19113566">10.3390/ijms19113566</a>'
  apa: 'Hille, S., Akhmanova, M., Glanc, M., Johnson, A. J., &#38; Friml, J. (2018).
    Relative contribution of PIN-containing secretory vesicles and plasma membrane
    PINs to the directed auxin transport: Theoretical estimation. <i>International
    Journal of Molecular Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms19113566">https://doi.org/10.3390/ijms19113566</a>'
  chicago: 'Hille, Sander, Maria Akhmanova, Matous Glanc, Alexander J Johnson, and
    Jiří Friml. “Relative Contribution of PIN-Containing Secretory Vesicles and Plasma
    Membrane PINs to the Directed Auxin Transport: Theoretical Estimation.” <i>International
    Journal of Molecular Sciences</i>. MDPI, 2018. <a href="https://doi.org/10.3390/ijms19113566">https://doi.org/10.3390/ijms19113566</a>.'
  ieee: 'S. Hille, M. Akhmanova, M. Glanc, A. J. Johnson, and J. Friml, “Relative
    contribution of PIN-containing secretory vesicles and plasma membrane PINs to
    the directed auxin transport: Theoretical estimation,” <i>International Journal
    of Molecular Sciences</i>, vol. 19, no. 11. MDPI, 2018.'
  ista: 'Hille S, Akhmanova M, Glanc M, Johnson AJ, Friml J. 2018. Relative contribution
    of PIN-containing secretory vesicles and plasma membrane PINs to the directed
    auxin transport: Theoretical estimation. International Journal of Molecular Sciences.
    19(11).'
  mla: 'Hille, Sander, et al. “Relative Contribution of PIN-Containing Secretory Vesicles
    and Plasma Membrane PINs to the Directed Auxin Transport: Theoretical Estimation.”
    <i>International Journal of Molecular Sciences</i>, vol. 19, no. 11, MDPI, 2018,
    doi:<a href="https://doi.org/10.3390/ijms19113566">10.3390/ijms19113566</a>.'
  short: S. Hille, M. Akhmanova, M. Glanc, A.J. Johnson, J. Friml, International Journal
    of Molecular Sciences 19 (2018).
date_created: 2018-12-11T11:44:09Z
date_published: 2018-11-12T00:00:00Z
date_updated: 2025-04-14T07:45:00Z
day: '12'
ddc:
- '580'
department:
- _id: DaSi
- _id: JiFr
doi: 10.3390/ijms19113566
ec_funded: 1
external_id:
  isi:
  - '000451528500282'
file:
- access_level: open_access
  checksum: e4b59c2599b0ca26ebf5b8434bcde94a
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-17T16:04:11Z
  date_updated: 2020-07-14T12:44:50Z
  file_id: '5719'
  file_name: 2018_IJMS_Hille.pdf
  file_size: 2200593
  relation: main_file
file_date_updated: 2020-07-14T12:44:50Z
has_accepted_license: '1'
intvolume: '        19'
isi: 1
issue: '11'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - 1422-0067
publication_status: published
publisher: MDPI
publist_id: '8042'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Relative contribution of PIN-containing secretory vesicles and plasma membrane
  PINs to the directed auxin transport: Theoretical estimation'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 19
year: '2018'
...
