---
_id: '2974'
abstract:
- lang: eng
  text: "We construct a perfectly binding string commitment scheme whose security
    is based on the learning parity with noise (LPN) assumption, or equivalently,
    the hardness of decoding random linear codes. Our scheme not only allows for a
    simple and efficient zero-knowledge proof of knowledge for committed values (essentially
    a Σ-protocol), but also for such proofs showing any kind of relation amongst committed
    values, i.e. proving that messages m_0,...,m_u, are such that m_0=C(m_1,...,m_u)
    for any circuit C.\r\n\r\nTo get soundness which is exponentially small in a security
    parameter t, and when the zero-knowledge property relies on the LPN problem with
    secrets of length l, our 3 round protocol has communication complexity O(t|C|l
    log(l)) and computational complexity of O(t|C|l) bit operations. The hidden constants
    are small, and the computation consists mostly of computing inner products of
    bit-vectors."
acknowledgement: "We are grateful to Petros Mol for helpful discussions on the reduction
  for the hardness of the xLPN problem.\r\n"
alternative_title:
- LNCS
author:
- first_name: Abhishek
  full_name: Jain, Abhishek
  last_name: Jain
- first_name: Stephan
  full_name: Krenn, Stephan
  id: 329FCCF0-F248-11E8-B48F-1D18A9856A87
  last_name: Krenn
  orcid: 0000-0003-2835-9093
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Aris
  full_name: Tentes, Aris
  last_name: Tentes
citation:
  ama: 'Jain A, Krenn S, Pietrzak KZ, Tentes A. Commitments and efficient zero knowledge
    proofs from learning parity with noise. In: Wang X, Sako K, eds. Vol 7658. Springer;
    2012:663-680. doi:<a href="https://doi.org/10.1007/978-3-642-34961-4_40">10.1007/978-3-642-34961-4_40</a>'
  apa: 'Jain, A., Krenn, S., Pietrzak, K. Z., &#38; Tentes, A. (2012). Commitments
    and efficient zero knowledge proofs from learning parity with noise. In X. Wang
    &#38; K. Sako (Eds.) (Vol. 7658, pp. 663–680). Presented at the ASIACRYPT: Theory
    and Application of Cryptology and Information Security, Beijing, China: Springer.
    <a href="https://doi.org/10.1007/978-3-642-34961-4_40">https://doi.org/10.1007/978-3-642-34961-4_40</a>'
  chicago: Jain, Abhishek, Stephan Krenn, Krzysztof Z Pietrzak, and Aris Tentes. “Commitments
    and Efficient Zero Knowledge Proofs from Learning Parity with Noise.” edited by
    Xiaoyun Wang and Kazue Sako, 7658:663–80. Springer, 2012. <a href="https://doi.org/10.1007/978-3-642-34961-4_40">https://doi.org/10.1007/978-3-642-34961-4_40</a>.
  ieee: 'A. Jain, S. Krenn, K. Z. Pietrzak, and A. Tentes, “Commitments and efficient
    zero knowledge proofs from learning parity with noise,” presented at the ASIACRYPT:
    Theory and Application of Cryptology and Information Security, Beijing, China,
    2012, vol. 7658, pp. 663–680.'
  ista: 'Jain A, Krenn S, Pietrzak KZ, Tentes A. 2012. Commitments and efficient zero
    knowledge proofs from learning parity with noise. ASIACRYPT: Theory and Application
    of Cryptology and Information Security, LNCS, vol. 7658, 663–680.'
  mla: Jain, Abhishek, et al. <i>Commitments and Efficient Zero Knowledge Proofs from
    Learning Parity with Noise</i>. Edited by Xiaoyun Wang and Kazue Sako, vol. 7658,
    Springer, 2012, pp. 663–80, doi:<a href="https://doi.org/10.1007/978-3-642-34961-4_40">10.1007/978-3-642-34961-4_40</a>.
  short: A. Jain, S. Krenn, K.Z. Pietrzak, A. Tentes, in:, X. Wang, K. Sako (Eds.),
    Springer, 2012, pp. 663–680.
conference:
  end_date: 2012-12-06
  location: Beijing, China
  name: 'ASIACRYPT: Theory and Application of Cryptology and Information Security'
  start_date: 2012-12-02
date_created: 2018-12-11T12:00:38Z
date_published: 2012-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:11Z
day: '01'
ddc:
- '004'
- '005'
department:
- _id: KrPi
doi: 10.1007/978-3-642-34961-4_40
ec_funded: 1
editor:
- first_name: Xiaoyun
  full_name: Wang, Xiaoyun
  last_name: Wang
- first_name: Kazue
  full_name: Sako, Kazue
  last_name: Sako
file:
- access_level: open_access
  checksum: ab879537385efc4cb4203e7ef0fea17b
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:00Z
  date_updated: 2020-07-14T12:45:58Z
  file_id: '5048'
  file_name: IST-2016-721-v1+1_513.pdf
  file_size: 482570
  relation: main_file
file_date_updated: 2020-07-14T12:45:58Z
fulldoi: https://doi.org/10.1007/978-3-642-34961-4_40
has_accepted_license: '1'
intvolume: '      7658'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Submitted Version
page: 663 - 680
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '259668'
  name: Provable Security for Physical Cryptography
publication_status: published
publisher: Springer
publist_id: '3730'
pubrep_id: '721'
scopus_import: 1
status: public
title: Commitments and efficient zero knowledge proofs from learning parity with noise
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7658
year: '2012'
...
---
_id: '12198'
abstract:
- lang: eng
  text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes
    DNA demethylation before fertilization, but the targeting preferences, mechanism,
    and biological significance of this process remain unclear. Here, we show that
    active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for
    all of the demethylation in the central cell and preferentially targets small,
    AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative
    cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation
    of similar sequences, and lack of DEMETER in vegetative cells causes reduced small
    RNA–directed DNA methylation of transposons in sperm. Our results demonstrate
    that demethylation in companion cells reinforces transposon methylation in plant
    gametes and likely contributes to stable silencing of transposable elements across
    generations.
acknowledgement: We thank S. Harmer for assistance with the analysis of histone modifications,
  the BioOptics team at the Vienna Biocenter Campus for sorting sperm and vegetative
  cell nuclei, K. Slotkin for the LAT52p-amiRNA=GFP plasmid, and G. Drews for the
  DD45p-GFP transgenic line. This work was partially funded by an NIH grant (GM69415)
  to R.L.F., NSF grants (MCB-0918821 and IOS-1025890) to R.L.F. and D.Z., a Young
  Investigator Grant from the Arnold and Mabel Beckman Foundation to D.Z., an Austrian
  Science Fund (FWF) grant P21389-B03 to H.T., a Ruth L. Kirschstein NIH Predoctoral
  Fellowship (GM093633) to C.A.I., a Fulbright Scholarship to J.A.R., a fellowship
  from the Jane Coffin Childs Memorial Fund to A.Z., and a Robert and Colleen Haas
  Scholarship to D.R. Sequencing data are deposited in GEO (GSE38935).
article_processing_charge: No
article_type: original
author:
- first_name: Christian A.
  full_name: Ibarra, Christian A.
  last_name: Ibarra
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Vera K.
  full_name: Schoft, Vera K.
  last_name: Schoft
- first_name: Tzung-Fu
  full_name: Hsieh, Tzung-Fu
  last_name: Hsieh
- first_name: Rie
  full_name: Uzawa, Rie
  last_name: Uzawa
- first_name: Jessica A.
  full_name: Rodrigues, Jessica A.
  last_name: Rodrigues
- first_name: Assaf
  full_name: Zemach, Assaf
  last_name: Zemach
- first_name: Nina
  full_name: Chumak, Nina
  last_name: Chumak
- first_name: Adriana
  full_name: Machlicova, Adriana
  last_name: Machlicova
- first_name: Toshiro
  full_name: Nishimura, Toshiro
  last_name: Nishimura
- first_name: Denisse
  full_name: Rojas, Denisse
  last_name: Rojas
- first_name: Robert L.
  full_name: Fischer, Robert L.
  last_name: Fischer
- first_name: Hisashi
  full_name: Tamaru, Hisashi
  last_name: Tamaru
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion
    cells reinforces transposon methylation in gametes. <i>Science</i>. 2012;337(6100):1360-1364.
    doi:<a href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>
  apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues,
    J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>
  chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie
    Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in
    Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>.
    American Association for the Advancement of Science, 2012. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>.
  ieee: C. A. Ibarra <i>et al.</i>, “Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes,” <i>Science</i>, vol. 337, no. 6100.
    American Association for the Advancement of Science, pp. 1360–1364, 2012.
  ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A,
    Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman
    D. 2012. Active DNA demethylation in plant companion cells reinforces transposon
    methylation in gametes. Science. 337(6100), 1360–1364.
  mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells
    Reinforces Transposon Methylation in Gametes.” <i>Science</i>, vol. 337, no. 6100,
    American Association for the Advancement of Science, 2012, pp. 1360–64, doi:<a
    href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>.
  short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues,
    A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H.
    Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.
date_created: 2023-01-16T09:21:24Z
date_published: 2012-09-14T00:00:00Z
date_updated: 2025-01-14T12:37:28Z
day: '14'
department:
- _id: XiFe
doi: 10.1126/science.1224839
extern: '1'
external_id:
  pmid:
  - '22984074'
fulldoi: https://doi.org/10.1126/science.1224839
intvolume: '       337'
issue: '6100'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/
month: '09'
oa: 1
oa_version: Published Version
page: 1360-1364
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active DNA demethylation in plant companion cells reinforces transposon methylation
  in gametes
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 337
year: '2012'
...
---
_id: '13075'
abstract:
- lang: eng
  text: Little is known about the stability of trophic relationships in complex natural
    communities over evolutionary timescales. Here, we use sequence data from 18 nuclear
    loci to reconstruct and compare the intraspecific histories of major Pleistocene
    refugial populations in the Middle East, the Balkans and Iberia in a guild of
    four Chalcid parasitoids (Cecidostiba fungosa, C. semifascia, Hobbya stenonota
    and Mesopolobus amaenus) all attacking Cynipid oak galls. We develop a likelihood
    method to numerically estimate models of divergence between three populations
    from multilocus data. We investigate the power of this framework on simulated
    data, and - using triplet alignments of intronic loci - quantify the support for
    all possible divergence relationships between refugial populations in the four
    parasitoids. Although an East to West order of population divergence has highest
    support in all but one species, we cannot rule out alternative population tree
    topologies. Comparing the estimated times of population splits between species,
    we find that one species, M. amaenus, has a significantly older history than the
    rest of the guild and must have arrived in central Europe at least one glacial
    cycle prior to other guild members. This suggests that although all four species
    may share a common origin in the East, they expanded westwards into Europe at
    different times.
article_processing_charge: No
author:
- first_name: Konrad
  full_name: Lohse, Konrad
  last_name: Lohse
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Graham
  full_name: Stone, Graham
  last_name: Stone
- first_name: George
  full_name: Melika, George
  last_name: Melika
citation:
  ama: 'Lohse K, Barton NH, Stone G, Melika G. Data from: A likelihood-based comparison
    of population histories in a parasitoid guild. 2012. doi:<a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>'
  apa: 'Lohse, K., Barton, N. H., Stone, G., &#38; Melika, G. (2012). Data from: A
    likelihood-based comparison of population histories in a parasitoid guild. Dryad.
    <a href="https://doi.org/10.5061/DRYAD.0G0FS">https://doi.org/10.5061/DRYAD.0G0FS</a>'
  chicago: 'Lohse, Konrad, Nicholas H Barton, Graham Stone, and George Melika. “Data
    from: A Likelihood-Based Comparison of Population Histories in a Parasitoid Guild.”
    Dryad, 2012. <a href="https://doi.org/10.5061/DRYAD.0G0FS">https://doi.org/10.5061/DRYAD.0G0FS</a>.'
  ieee: 'K. Lohse, N. H. Barton, G. Stone, and G. Melika, “Data from: A likelihood-based
    comparison of population histories in a parasitoid guild.” Dryad, 2012.'
  ista: 'Lohse K, Barton NH, Stone G, Melika G. 2012. Data from: A likelihood-based
    comparison of population histories in a parasitoid guild, Dryad, <a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>.'
  mla: 'Lohse, Konrad, et al. <i>Data from: A Likelihood-Based Comparison of Population
    Histories in a Parasitoid Guild</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/DRYAD.0G0FS">10.5061/DRYAD.0G0FS</a>.'
  short: K. Lohse, N.H. Barton, G. Stone, G. Melika, (2012).
date_created: 2023-05-23T17:01:02Z
date_published: 2012-06-08T00:00:00Z
date_updated: 2025-09-30T08:04:02Z
day: '08'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.0G0FS
fulldoi: https://doi.org/10.5061/DRYAD.0G0FS
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.0g0fs
month: '06'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '2968'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: A likelihood-based comparison of population histories in a parasitoid
  guild'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '1384'
abstract:
- lang: eng
  text: 'Software model checking, as an undecidable problem, has three possible outcomes:
    (1) the program satisfies the specification, (2) the program does not satisfy
    the specification, and (3) the model checker fails. The third outcome usually
    manifests itself in a space-out, time-out, or one component of the verification
    tool giving up; in all of these failing cases, significant computation is performed
    by the verification tool before the failure, but no result is reported. We propose
    to reformulate the model-checking problem as follows, in order to have the verification
    tool report a summary of the performed work even in case of failure: given a program
    and a specification, the model checker returns a condition Ψ - usually a state
    predicate - such that the program satisfies the specification under the condition
    Ψ - that is, as long as the program does not leave the states in which Ψ is satisfied.
    In our experiments, we investigated as one major application of conditional model
    checking the sequential combination of model checkers with information passing.
    We give the condition that one model checker produces, as input to a second conditional
    model checker, such that the verification problem for the second is restricted
    to the part of the state space that is not covered by the condition, i.e., the
    second model checker works on the problems that the first model checker could
    not solve. Our experiments demonstrate that repeated application of conditional
    model checkers, passing information from one model checker to the next, can significantly
    improve the verification results and performance, i.e., we can now verify programs
    that we could not verify before.'
acknowledgement: This  research  was  supported  by  the  Canadian  NSERC grant   RGPIN   341819-07,    the   ERC   Advanced   Grant
  QUAREM, and the Austrian Science Fund NFN RiSE.
article_number: '57'
article_processing_charge: No
arxiv: 1
author:
- first_name: Dirk
  full_name: Beyer, Dirk
  last_name: Beyer
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Mehmet
  full_name: Keremoglu, Mehmet
  last_name: Keremoglu
- first_name: Philipp
  full_name: Wendler, Philipp
  last_name: Wendler
citation:
  ama: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. Conditional model checking:
    A technique to pass information between verifiers. In: <i>Proceedings of the ACM
    SIGSOFT 20th International Symposium on the Foundations of Software Engineering</i>.
    ACM; 2012. doi:<a href="https://doi.org/10.1145/2393596.2393664">10.1145/2393596.2393664</a>'
  apa: 'Beyer, D., Henzinger, T. A., Keremoglu, M., &#38; Wendler, P. (2012). Conditional
    model checking: A technique to pass information between verifiers. In <i>Proceedings
    of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
    Engineering</i>. Cary, NC, USA: ACM. <a href="https://doi.org/10.1145/2393596.2393664">https://doi.org/10.1145/2393596.2393664</a>'
  chicago: 'Beyer, Dirk, Thomas A Henzinger, Mehmet Keremoglu, and Philipp Wendler.
    “Conditional Model Checking: A Technique to Pass Information between Verifiers.”
    In <i>Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
    of Software Engineering</i>. ACM, 2012. <a href="https://doi.org/10.1145/2393596.2393664">https://doi.org/10.1145/2393596.2393664</a>.'
  ieee: 'D. Beyer, T. A. Henzinger, M. Keremoglu, and P. Wendler, “Conditional model
    checking: A technique to pass information between verifiers,” in <i>Proceedings
    of the ACM SIGSOFT 20th International Symposium on the Foundations of Software
    Engineering</i>, Cary, NC, USA, 2012.'
  ista: 'Beyer D, Henzinger TA, Keremoglu M, Wendler P. 2012. Conditional model checking:
    A technique to pass information between verifiers. Proceedings of the ACM SIGSOFT
    20th International Symposium on the Foundations of Software Engineering. FSE:
    Foundations of Software Engineering, 57.'
  mla: 'Beyer, Dirk, et al. “Conditional Model Checking: A Technique to Pass Information
    between Verifiers.” <i>Proceedings of the ACM SIGSOFT 20th International Symposium
    on the Foundations of Software Engineering</i>, 57, ACM, 2012, doi:<a href="https://doi.org/10.1145/2393596.2393664">10.1145/2393596.2393664</a>.'
  short: D. Beyer, T.A. Henzinger, M. Keremoglu, P. Wendler, in:, Proceedings of the
    ACM SIGSOFT 20th International Symposium on the Foundations of Software Engineering,
    ACM, 2012.
conference:
  end_date: 2012-11-16
  location: Cary, NC, USA
  name: 'FSE: Foundations of Software Engineering'
  start_date: 2012-11-11
date_created: 2018-12-11T11:51:42Z
date_published: 2012-11-01T00:00:00Z
date_updated: 2025-06-11T08:07:37Z
day: '01'
department:
- _id: ToHe
doi: 10.1145/2393596.2393664
ec_funded: 1
external_id:
  arxiv:
  - '1109.6926'
fulldoi: https://doi.org/10.1145/2393596.2393664
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1109.6926
month: '11'
oa: 1
oa_version: Preprint
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication: Proceedings of the ACM SIGSOFT 20th International Symposium on the Foundations
  of Software Engineering
publication_status: published
publisher: ACM
publist_id: '5826'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Conditional model checking: A technique to pass information between verifiers'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '493'
abstract:
- lang: eng
  text: 'The BCI competition IV stands in the tradition of prior BCI competitions
    that aim to provide high quality neuroscientific data for open access to the scientific
    community. As experienced already in prior competitions not only scientists from
    the narrow field of BCI compete, but scholars with a broad variety of backgrounds
    and nationalities. They include high specialists as well as students.The goals
    of all BCI competitions have always been to challenge with respect to novel paradigms
    and complex data. We report on the following challenges: (1) asynchronous data,
    (2) synthetic, (3) multi-class continuous data, (4) sessionto-session transfer,
    (5) directionally modulated MEG, (6) finger movements recorded by ECoG. As after
    past competitions, our hope is that winning entries may enhance the analysis methods
    of future BCIs.'
acknowledgement: "The studies were in part or completely supported by the Bundesministerium
  für Bildung und Forschung (BMBF), Fkz 01IB001A, 01GQ0850, by the German Science
  Foundation (DFG, contract MU 987/3-2), by the European ICT Programme Projects FP7-224631
  and 216886, the World Class University Program through the National Research Foundation
  of Korea funded by the Ministry of Education, Science, and Technology (Grant R31-10008),
  the US Army Research Office [W911NF-08-1-0216 (Gerwin Schalk) and W911NF-07-1-0415
  (Gerwin Schalk)] and the NIH [EB006356 (Gerwin Schalk) and EB000856 (Gerwin Schalk),
  the WIN-Kolleg of the Heidelberg Academy of Sciences and Humanities, German Federal
  Ministry of Education and Research grants 01GQ0420, 01GQ0761, 01GQ0762, and 01GQ0830,
  German Research Foundation grants 550/B5 and C6, and by a scholarship from the German
  National Academic Foundation. This paper only reflects the authors’ views and funding
  agencies are not liable for any use that may be made of the information contained
  herein.\r\n"
article_number: '55'
article_processing_charge: No
author:
- first_name: Michael
  full_name: Tangermann, Michael
  last_name: Tangermann
- first_name: Klaus
  full_name: Müller, Klaus
  last_name: Müller
- first_name: Ad
  full_name: Aertsen, Ad
  last_name: Aertsen
- first_name: Niels
  full_name: Birbaumer, Niels
  last_name: Birbaumer
- first_name: Christoph
  full_name: Braun, Christoph
  last_name: Braun
- first_name: Clemens
  full_name: Brunner, Clemens
  last_name: Brunner
- first_name: Robert
  full_name: Leeb, Robert
  last_name: Leeb
- first_name: Carsten
  full_name: Mehring, Carsten
  last_name: Mehring
- first_name: Kai
  full_name: Miller, Kai
  last_name: Miller
- first_name: Gernot
  full_name: Müller Putz, Gernot
  last_name: Müller Putz
- first_name: Guido
  full_name: Nolte, Guido
  last_name: Nolte
- first_name: Gert
  full_name: Pfurtscheller, Gert
  last_name: Pfurtscheller
- first_name: Hubert
  full_name: Preissl, Hubert
  last_name: Preissl
- first_name: Gerwin
  full_name: Schalk, Gerwin
  last_name: Schalk
- first_name: Alois
  full_name: Schlögl, Alois
  id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
  last_name: Schlögl
  orcid: 0000-0002-5621-8100
- first_name: Carmen
  full_name: Vidaurre, Carmen
  last_name: Vidaurre
- first_name: Stephan
  full_name: Waldert, Stephan
  last_name: Waldert
- first_name: Benjamin
  full_name: Blankertz, Benjamin
  last_name: Blankertz
citation:
  ama: Tangermann M, Müller K, Aertsen A, et al. Review of the BCI competition IV.
    <i>Frontiers in Neuroscience</i>. 2012;6. doi:<a href="https://doi.org/10.3389/fnins.2012.00055">10.3389/fnins.2012.00055</a>
  apa: Tangermann, M., Müller, K., Aertsen, A., Birbaumer, N., Braun, C., Brunner,
    C., … Blankertz, B. (2012). Review of the BCI competition IV. <i>Frontiers in
    Neuroscience</i>. Frontiers Research Foundation. <a href="https://doi.org/10.3389/fnins.2012.00055">https://doi.org/10.3389/fnins.2012.00055</a>
  chicago: Tangermann, Michael, Klaus Müller, Ad Aertsen, Niels Birbaumer, Christoph
    Braun, Clemens Brunner, Robert Leeb, et al. “Review of the BCI Competition IV.”
    <i>Frontiers in Neuroscience</i>. Frontiers Research Foundation, 2012. <a href="https://doi.org/10.3389/fnins.2012.00055">https://doi.org/10.3389/fnins.2012.00055</a>.
  ieee: M. Tangermann <i>et al.</i>, “Review of the BCI competition IV,” <i>Frontiers
    in Neuroscience</i>, vol. 6. Frontiers Research Foundation, 2012.
  ista: Tangermann M, Müller K, Aertsen A, Birbaumer N, Braun C, Brunner C, Leeb R,
    Mehring C, Miller K, Müller Putz G, Nolte G, Pfurtscheller G, Preissl H, Schalk
    G, Schlögl A, Vidaurre C, Waldert S, Blankertz B. 2012. Review of the BCI competition
    IV. Frontiers in Neuroscience. 6, 55.
  mla: Tangermann, Michael, et al. “Review of the BCI Competition IV.” <i>Frontiers
    in Neuroscience</i>, vol. 6, 55, Frontiers Research Foundation, 2012, doi:<a href="https://doi.org/10.3389/fnins.2012.00055">10.3389/fnins.2012.00055</a>.
  short: M. Tangermann, K. Müller, A. Aertsen, N. Birbaumer, C. Braun, C. Brunner,
    R. Leeb, C. Mehring, K. Miller, G. Müller Putz, G. Nolte, G. Pfurtscheller, H.
    Preissl, G. Schalk, A. Schlögl, C. Vidaurre, S. Waldert, B. Blankertz, Frontiers
    in Neuroscience 6 (2012).
date_created: 2018-12-11T11:46:46Z
date_published: 2012-07-13T00:00:00Z
date_updated: 2025-09-30T08:35:59Z
day: '13'
ddc:
- '004'
department:
- _id: ScienComp
- _id: PeJo
doi: 10.3389/fnins.2012.00055
external_id:
  isi:
  - '000209165300066'
file:
- access_level: open_access
  checksum: 195238221c4b0b0f4035f6f6c16ea17c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:18:34Z
  date_updated: 2020-07-14T12:46:35Z
  file_id: '5356'
  file_name: IST-2018-945-v1+1_2012_Schloegl_Review_of.pdf
  file_size: 2693701
  relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
fulldoi: https://doi.org/10.3389/fnins.2012.00055
has_accepted_license: '1'
intvolume: '         6'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Frontiers in Neuroscience
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '7327'
pubrep_id: '945'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Review of the BCI competition IV
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 6
year: '2012'
...
---
_id: '495'
abstract:
- lang: eng
  text: An automaton with advice is a finite state automaton which has access to an
    additional fixed infinite string called an advice tape. We refine the Myhill-Nerode
    theorem to characterize the languages of finite strings that are accepted by automata
    with advice. We do the same for tree automata with advice.
alternative_title:
- EPTCS
author:
- first_name: Alex
  full_name: Kruckman, Alex
  last_name: Kruckman
- first_name: Sasha
  full_name: Rubin, Sasha
  id: 2EC51194-F248-11E8-B48F-1D18A9856A87
  last_name: Rubin
- first_name: John
  full_name: Sheridan, John
  last_name: Sheridan
- first_name: Ben
  full_name: Zax, Ben
  last_name: Zax
citation:
  ama: 'Kruckman A, Rubin S, Sheridan J, Zax B. A Myhill Nerode theorem for automata
    with advice. In: <i>Proceedings GandALF 2012</i>. Vol 96. Open Publishing Association;
    2012:238-246. doi:<a href="https://doi.org/10.4204/EPTCS.96.18">10.4204/EPTCS.96.18</a>'
  apa: 'Kruckman, A., Rubin, S., Sheridan, J., &#38; Zax, B. (2012). A Myhill Nerode
    theorem for automata with advice. In <i>Proceedings GandALF 2012</i> (Vol. 96,
    pp. 238–246). Napoli, Italy: Open Publishing Association. <a href="https://doi.org/10.4204/EPTCS.96.18">https://doi.org/10.4204/EPTCS.96.18</a>'
  chicago: Kruckman, Alex, Sasha Rubin, John Sheridan, and Ben Zax. “A Myhill Nerode
    Theorem for Automata with Advice.” In <i>Proceedings GandALF 2012</i>, 96:238–46.
    Open Publishing Association, 2012. <a href="https://doi.org/10.4204/EPTCS.96.18">https://doi.org/10.4204/EPTCS.96.18</a>.
  ieee: A. Kruckman, S. Rubin, J. Sheridan, and B. Zax, “A Myhill Nerode theorem for
    automata with advice,” in <i>Proceedings GandALF 2012</i>, Napoli, Italy, 2012,
    vol. 96, pp. 238–246.
  ista: 'Kruckman A, Rubin S, Sheridan J, Zax B. 2012. A Myhill Nerode theorem for
    automata with advice. Proceedings GandALF 2012. GandALF: Games, Automata, Logics
    and Formal Verification, EPTCS, vol. 96, 238–246.'
  mla: Kruckman, Alex, et al. “A Myhill Nerode Theorem for Automata with Advice.”
    <i>Proceedings GandALF 2012</i>, vol. 96, Open Publishing Association, 2012, pp.
    238–46, doi:<a href="https://doi.org/10.4204/EPTCS.96.18">10.4204/EPTCS.96.18</a>.
  short: A. Kruckman, S. Rubin, J. Sheridan, B. Zax, in:, Proceedings GandALF 2012,
    Open Publishing Association, 2012, pp. 238–246.
conference:
  end_date: 2012-09-08
  location: Napoli, Italy
  name: 'GandALF: Games, Automata, Logics and Formal Verification'
  start_date: 2012-09-06
corr_author: '1'
date_created: 2018-12-11T11:46:47Z
date_published: 2012-10-07T00:00:00Z
date_updated: 2024-10-09T20:55:00Z
day: '07'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.4204/EPTCS.96.18
ec_funded: 1
file:
- access_level: open_access
  checksum: 56277f95edc9d531fa3bdc5f9579fda8
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:15:31Z
  date_updated: 2020-07-14T12:46:35Z
  file_id: '5152'
  file_name: IST-2018-944-v1+1_2012_Rubin_A_Myhill.pdf
  file_size: 97736
  relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
fulldoi: https://doi.org/10.4204/EPTCS.96.18
has_accepted_license: '1'
intvolume: '        96'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 238 - 246
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication: Proceedings GandALF 2012
publication_status: published
publisher: Open Publishing Association
publist_id: '7325'
pubrep_id: '944'
quality_controlled: '1'
scopus_import: 1
status: public
title: A Myhill Nerode theorem for automata with advice
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 96
year: '2012'
...
---
_id: '496'
abstract:
- lang: eng
  text: 'We study the expressive power of logical interpretations on the class of
    scattered trees, namely those with countably many infinite branches. Scattered
    trees can be thought of as the tree analogue of scattered linear orders. Every
    scattered tree has an ordinal rank that reflects the structure of its infinite
    branches. We prove, roughly, that trees and orders of large rank cannot be interpreted
    in scattered trees of small rank. We consider a quite general notion of interpretation:
    each element of the interpreted structure is represented by a set of tuples of
    subsets of the interpreting tree. Our trees are countable, not necessarily finitely
    branching, and may have finitely many unary predicates as labellings. We also
    show how to replace injective set-interpretations in (not necessarily scattered)
    trees by ''finitary'' set-interpretations.'
alternative_title:
- LICS
article_number: '6280474'
article_processing_charge: No
author:
- first_name: Alexander
  full_name: Rabinovich, Alexander
  last_name: Rabinovich
- first_name: Sasha
  full_name: Rubin, Sasha
  id: 2EC51194-F248-11E8-B48F-1D18A9856A87
  last_name: Rubin
citation:
  ama: 'Rabinovich A, Rubin S. Interpretations in trees with countably many branches.
    In: IEEE; 2012. doi:<a href="https://doi.org/10.1109/LICS.2012.65">10.1109/LICS.2012.65</a>'
  apa: 'Rabinovich, A., &#38; Rubin, S. (2012). Interpretations in trees with countably
    many branches. Presented at the LICS: Logic in Computer Science, Dubrovnik, Croatia:
    IEEE. <a href="https://doi.org/10.1109/LICS.2012.65">https://doi.org/10.1109/LICS.2012.65</a>'
  chicago: Rabinovich, Alexander, and Sasha Rubin. “Interpretations in Trees with
    Countably Many Branches.” IEEE, 2012. <a href="https://doi.org/10.1109/LICS.2012.65">https://doi.org/10.1109/LICS.2012.65</a>.
  ieee: 'A. Rabinovich and S. Rubin, “Interpretations in trees with countably many
    branches,” presented at the LICS: Logic in Computer Science, Dubrovnik, Croatia,
    2012.'
  ista: 'Rabinovich A, Rubin S. 2012. Interpretations in trees with countably many
    branches. LICS: Logic in Computer Science, LICS, , 6280474.'
  mla: Rabinovich, Alexander, and Sasha Rubin. <i>Interpretations in Trees with Countably
    Many Branches</i>. 6280474, IEEE, 2012, doi:<a href="https://doi.org/10.1109/LICS.2012.65">10.1109/LICS.2012.65</a>.
  short: A. Rabinovich, S. Rubin, in:, IEEE, 2012.
conference:
  end_date: 2012-06-28
  location: Dubrovnik, Croatia
  name: 'LICS: Logic in Computer Science'
  start_date: 2012-06-25
date_created: 2018-12-11T11:46:47Z
date_published: 2012-01-01T00:00:00Z
date_updated: 2025-09-30T08:34:47Z
day: '01'
department:
- _id: KrCh
doi: 10.1109/LICS.2012.65
ec_funded: 1
external_id:
  isi:
  - '000309059900061'
fulldoi: https://doi.org/10.1109/LICS.2012.65
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arise.or.at/pubpdf/Interpretations_in_Trees_with_Countably_Many_Branches.pdf
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication_status: published
publisher: IEEE
publist_id: '7324'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Interpretations in trees with countably many branches
type: conference
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
year: '2012'
...
---
_id: '497'
abstract:
- lang: eng
  text: 'One central issue in the formal design and analysis of reactive systems is
    the notion of refinement that asks whether all behaviors of the implementation
    is allowed by the specification. The local interpretation of behavior leads to
    the notion of simulation. Alternating transition systems (ATSs) provide a general
    model for composite reactive systems, and the simulation relation for ATSs is
    known as alternating simulation. The simulation relation for fair transition systems
    is called fair simulation. In this work our main contributions are as follows:
    (1) We present an improved algorithm for fair simulation with Büchi fairness constraints;
    our algorithm requires O(n 3·m) time as compared to the previous known O(n 6)-time
    algorithm, where n is the number of states and m is the number of transitions.
    (2) We present a game based algorithm for alternating simulation that requires
    O(m2)-time as compared to the previous known O((n·m)2)-time algorithm, where n
    is the number of states and m is the size of transition relation. (3) We present
    an iterative algorithm for alternating simulation that matches the time complexity
    of the game based algorithm, but is more space efficient than the game based algorithm.
    © Krishnendu Chatterjee, Siddhesh Chaubal, and Pritish Kamath.'
alternative_title:
- LIPIcs
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Siddhesh
  full_name: Chaubal, Siddhesh
  last_name: Chaubal
- first_name: Pritish
  full_name: Kamath, Pritish
  last_name: Kamath
citation:
  ama: 'Chatterjee K, Chaubal S, Kamath P. Faster algorithms for alternating refinement
    relations. In: Vol 16. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2012:167-182.
    doi:<a href="https://doi.org/10.4230/LIPIcs.CSL.2012.167">10.4230/LIPIcs.CSL.2012.167</a>'
  apa: 'Chatterjee, K., Chaubal, S., &#38; Kamath, P. (2012). Faster algorithms for
    alternating refinement relations (Vol. 16, pp. 167–182). Presented at the EACSL:
    European Association for Computer Science Logic, Fontainebleau, France: Schloss
    Dagstuhl - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.CSL.2012.167">https://doi.org/10.4230/LIPIcs.CSL.2012.167</a>'
  chicago: Chatterjee, Krishnendu, Siddhesh Chaubal, and Pritish Kamath. “Faster Algorithms
    for Alternating Refinement Relations,” 16:167–82. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2012. <a href="https://doi.org/10.4230/LIPIcs.CSL.2012.167">https://doi.org/10.4230/LIPIcs.CSL.2012.167</a>.
  ieee: 'K. Chatterjee, S. Chaubal, and P. Kamath, “Faster algorithms for alternating
    refinement relations,” presented at the EACSL: European Association for Computer
    Science Logic, Fontainebleau, France, 2012, vol. 16, pp. 167–182.'
  ista: 'Chatterjee K, Chaubal S, Kamath P. 2012. Faster algorithms for alternating
    refinement relations. EACSL: European Association for Computer Science Logic,
    LIPIcs, vol. 16, 167–182.'
  mla: Chatterjee, Krishnendu, et al. <i>Faster Algorithms for Alternating Refinement
    Relations</i>. Vol. 16, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2012,
    pp. 167–82, doi:<a href="https://doi.org/10.4230/LIPIcs.CSL.2012.167">10.4230/LIPIcs.CSL.2012.167</a>.
  short: K. Chatterjee, S. Chaubal, P. Kamath, in:, Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2012, pp. 167–182.
conference:
  end_date: 2012-09-06
  location: Fontainebleau, France
  name: 'EACSL: European Association for Computer Science Logic'
  start_date: 2012-09-03
date_created: 2018-12-11T11:46:48Z
date_published: 2012-09-01T00:00:00Z
date_updated: 2025-01-14T12:24:50Z
day: '01'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.4230/LIPIcs.CSL.2012.167
ec_funded: 1
file:
- access_level: open_access
  checksum: f1b0dd99240800db2d7dbf9b5131fe5e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:50Z
  date_updated: 2020-07-14T12:46:35Z
  file_id: '4712'
  file_name: IST-2018-943-v1+1_2012_Chatterjee_Faster_Algorithms.pdf
  file_size: 471236
  relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
fulldoi: https://doi.org/10.4230/LIPIcs.CSL.2012.167
has_accepted_license: '1'
intvolume: '        16'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 167 - 182
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '7323'
pubrep_id: '943'
quality_controlled: '1'
related_material:
  record:
  - id: '5378'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: Faster algorithms for alternating refinement relations
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 16
year: '2012'
...
---
_id: '498'
abstract:
- lang: eng
  text: Understanding patterns and correlates of local adaptation in heterogeneous
    landscapes can provide important information in the selection of appropriate seed
    sources for restoration. We assessed the extent of local adaptation of fitness
    components in 12 population pairs of the perennial herb Rutidosis leptorrhynchoides
    (Asteraceae) and examined whether spatial scale (0.7-600 km), environmental distance,
    quantitative (QST) and neutral (FST) genetic differentiation, and size of the
    local and foreign populations could predict patterns of adaptive differentiation.
    Local adaptation varied among populations and fitness components. Including all
    population pairs, local adaptation was observed for seedling survival, but not
    for biomass, while foreign genotype advantage was observed for reproduction (number
    of inflorescences). Among population pairs, local adaptation increased with QST
    and local population size for biomass. QST was associated with environmental distance,
    suggesting ecological selection for phenotypic divergence. However, low FST and
    variation in population structure in small populations demonstrates the interaction
    of gene flow and drift in constraining local adaptation in R. leptorrhynchoides.
    Our study indicates that for species in heterogeneous landscapes, collecting seed
    from large populations from similar environments to candidate sites is likely
    to provide the most appropriate seed sources for restoration.
acknowledgement: "We thank Graham Pickup, David Steer, Linda Broadhurst, Lan Li and
  Carole Elliott for technical assistance. The New\r\nSouth Wales Department of Environment
  and Climate Change, ACT Parks, Conservation and Lands and the\r\nDepartment of Sustainability
  and Environment in Victoria provided permits for seed and soil collection. We thank\r\nSpencer
  C. H. Barrett for comments that improved the quality of the manuscript.\r\n"
article_processing_charge: No
author:
- first_name: Melinda
  full_name: Pickup, Melinda
  id: 2C78037E-F248-11E8-B48F-1D18A9856A87
  last_name: Pickup
  orcid: 0000-0001-6118-0541
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: David
  full_name: Rowell, David
  last_name: Rowell
- first_name: Andrew
  full_name: Young, Andrew
  last_name: Young
citation:
  ama: 'Pickup M, Field D, Rowell D, Young A. Predicting local adaptation in fragmented
    plant populations: Implications for restoration genetics. <i>Evolutionary Applications</i>.
    2012;5(8):913-924. doi:<a href="https://doi.org/10.1111/j.1752-4571.2012.00284.x">10.1111/j.1752-4571.2012.00284.x</a>'
  apa: 'Pickup, M., Field, D., Rowell, D., &#38; Young, A. (2012). Predicting local
    adaptation in fragmented plant populations: Implications for restoration genetics.
    <i>Evolutionary Applications</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1752-4571.2012.00284.x">https://doi.org/10.1111/j.1752-4571.2012.00284.x</a>'
  chicago: 'Pickup, Melinda, David Field, David Rowell, and Andrew Young. “Predicting
    Local Adaptation in Fragmented Plant Populations: Implications for Restoration
    Genetics.” <i>Evolutionary Applications</i>. Wiley-Blackwell, 2012. <a href="https://doi.org/10.1111/j.1752-4571.2012.00284.x">https://doi.org/10.1111/j.1752-4571.2012.00284.x</a>.'
  ieee: 'M. Pickup, D. Field, D. Rowell, and A. Young, “Predicting local adaptation
    in fragmented plant populations: Implications for restoration genetics,” <i>Evolutionary
    Applications</i>, vol. 5, no. 8. Wiley-Blackwell, pp. 913–924, 2012.'
  ista: 'Pickup M, Field D, Rowell D, Young A. 2012. Predicting local adaptation in
    fragmented plant populations: Implications for restoration genetics. Evolutionary
    Applications. 5(8), 913–924.'
  mla: 'Pickup, Melinda, et al. “Predicting Local Adaptation in Fragmented Plant Populations:
    Implications for Restoration Genetics.” <i>Evolutionary Applications</i>, vol.
    5, no. 8, Wiley-Blackwell, 2012, pp. 913–24, doi:<a href="https://doi.org/10.1111/j.1752-4571.2012.00284.x">10.1111/j.1752-4571.2012.00284.x</a>.'
  short: M. Pickup, D. Field, D. Rowell, A. Young, Evolutionary Applications 5 (2012)
    913–924.
corr_author: '1'
date_created: 2018-12-11T11:46:48Z
date_published: 2012-12-01T00:00:00Z
date_updated: 2025-09-30T08:33:55Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1111/j.1752-4571.2012.00284.x
external_id:
  isi:
  - '000312808900013'
file:
- access_level: open_access
  checksum: 233007138606aca5a2f75f7ae1742f43
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:33Z
  date_updated: 2020-07-14T12:46:35Z
  file_id: '4821'
  file_name: IST-2018-942-v1+1_Pickup_et_al-2012-Evolutionary_Applications.pdf
  file_size: 396136
  relation: main_file
file_date_updated: 2020-07-14T12:46:35Z
fulldoi: https://doi.org/10.1111/j.1752-4571.2012.00284.x
has_accepted_license: '1'
intvolume: '         5'
isi: 1
issue: '8'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 913 - 924
publication: Evolutionary Applications
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7322'
pubrep_id: '942'
quality_controlled: '1'
status: public
title: 'Predicting local adaptation in fragmented plant populations: Implications
  for restoration genetics'
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 5
year: '2012'
...
---
_id: '5377'
abstract:
- lang: eng
  text: 'Two-player games on graphs are central in many problems in formal verification
    and program analysis such as synthesis and verification of open systems. In this
    work we consider solving recursive game graphs (or pushdown game graphs) that
    can model the control flow of sequential programs with recursion. While pushdown
    games have been studied before with qualitative objectives, such as reachability
    and ω-regular objectives, in this work we study for the first time such games
    with the most well-studied quantitative objective, namely, mean-payoff objectives.
    In pushdown games two types of strategies are relevant: (1) global strategies,
    that depend on the entire global history; and (2) modular strategies, that have
    only local memory and thus do not depend on the context of invocation, but only
    on the history of the current invocation of the module. Our main results are as
    follows: (1) One-player pushdown games with mean-payoff objectives under global
    strategies are decidable in polynomial time. (2) Two- player pushdown games with
    mean-payoff objectives under global strategies are undecidable. (3) One-player
    pushdown games with mean-payoff objectives under modular strategies are NP- hard.
    (4) Two-player pushdown games with mean-payoff objectives under modular strategies
    can be solved in NP (i.e., both one-player and two-player pushdown games with
    mean-payoff objectives under modular strategies are NP-complete). We also establish
    the optimal strategy complexity showing that global strategies for mean-payoff
    objectives require infinite memory even in one-player pushdown games; and memoryless
    modular strategies are sufficient in two- player pushdown games. Finally we also
    show that all the problems have the same complexity if the stack boundedness condition
    is added, where along with the mean-payoff objective the player must also ensure
    that the stack height is bounded.'
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Yaron
  full_name: Velner, Yaron
  last_name: Velner
citation:
  ama: Chatterjee K, Velner Y. <i>Mean-Payoff Pushdown Games</i>. IST Austria; 2012.
    doi:<a href="https://doi.org/10.15479/AT:IST-2012-0002">10.15479/AT:IST-2012-0002</a>
  apa: Chatterjee, K., &#38; Velner, Y. (2012). <i>Mean-payoff pushdown games</i>.
    IST Austria. <a href="https://doi.org/10.15479/AT:IST-2012-0002">https://doi.org/10.15479/AT:IST-2012-0002</a>
  chicago: Chatterjee, Krishnendu, and Yaron Velner. <i>Mean-Payoff Pushdown Games</i>.
    IST Austria, 2012. <a href="https://doi.org/10.15479/AT:IST-2012-0002">https://doi.org/10.15479/AT:IST-2012-0002</a>.
  ieee: K. Chatterjee and Y. Velner, <i>Mean-payoff pushdown games</i>. IST Austria,
    2012.
  ista: Chatterjee K, Velner Y. 2012. Mean-payoff pushdown games, IST Austria, 33p.
  mla: Chatterjee, Krishnendu, and Yaron Velner. <i>Mean-Payoff Pushdown Games</i>.
    IST Austria, 2012, doi:<a href="https://doi.org/10.15479/AT:IST-2012-0002">10.15479/AT:IST-2012-0002</a>.
  short: K. Chatterjee, Y. Velner, Mean-Payoff Pushdown Games, IST Austria, 2012.
corr_author: '1'
date_created: 2018-12-12T11:38:59Z
date_published: 2012-07-02T00:00:00Z
date_updated: 2025-09-30T08:08:12Z
day: '02'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2012-0002
file:
- access_level: open_access
  checksum: a03c08c1589dbb0c96183a8bcf3ab240
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:00Z
  date_updated: 2020-07-14T12:46:38Z
  file_id: '5522'
  file_name: IST-2012-002_IST-2012-0002.pdf
  file_size: 592098
  relation: main_file
file_date_updated: 2020-07-14T12:46:38Z
fulldoi: https://doi.org/10.15479/AT:IST-2012-0002
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '33'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '10'
related_material:
  record:
  - id: '2956'
    relation: later_version
    status: public
status: public
title: Mean-payoff pushdown games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5378'
abstract:
- lang: eng
  text: 'One central issue in the formal design and analysis of reactive systems is
    the notion of refinement that asks whether all behaviors of the implementation
    is allowed by the specification. The local interpretation of behavior leads to
    the notion of simulation. Alternating transition systems (ATSs) provide a general
    model for composite reactive systems, and the simulation relation for ATSs is
    known as alternating simulation. The simulation relation for fair transition systems
    is called fair simulation. In this work our main contributions are as follows:
    (1) We present an improved algorithm for fair simulation with Büchi fairness constraints;
    our algorithm requires O(n3 · m) time as compared to the previous known O(n6)-time
    algorithm, where n is the number of states and m is the number of transitions.
    (2) We present a game based algorithm for alternating simulation that requires
    O(m2)-time as compared to the previous known O((n · m)2)-time algorithm, where
    n is the number of states and m is the size of transition relation. (3) We present
    an iterative algorithm for alternating simulation that matches the time complexity
    of the game based algorithm, but is more space efficient than the game based algorithm.'
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Siddhesh
  full_name: Chaubal, Siddhesh
  last_name: Chaubal
- first_name: Pritish
  full_name: Kamath, Pritish
  last_name: Kamath
citation:
  ama: Chatterjee K, Chaubal S, Kamath P. <i>Faster Algorithms for Alternating Refinement
    Relations</i>. IST Austria; 2012. doi:<a href="https://doi.org/10.15479/AT:IST-2012-0001">10.15479/AT:IST-2012-0001</a>
  apa: Chatterjee, K., Chaubal, S., &#38; Kamath, P. (2012). <i>Faster algorithms
    for alternating refinement relations</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2012-0001">https://doi.org/10.15479/AT:IST-2012-0001</a>
  chicago: Chatterjee, Krishnendu, Siddhesh Chaubal, and Pritish Kamath. <i>Faster
    Algorithms for Alternating Refinement Relations</i>. IST Austria, 2012. <a href="https://doi.org/10.15479/AT:IST-2012-0001">https://doi.org/10.15479/AT:IST-2012-0001</a>.
  ieee: K. Chatterjee, S. Chaubal, and P. Kamath, <i>Faster algorithms for alternating
    refinement relations</i>. IST Austria, 2012.
  ista: Chatterjee K, Chaubal S, Kamath P. 2012. Faster algorithms for alternating
    refinement relations, IST Austria, 21p.
  mla: Chatterjee, Krishnendu, et al. <i>Faster Algorithms for Alternating Refinement
    Relations</i>. IST Austria, 2012, doi:<a href="https://doi.org/10.15479/AT:IST-2012-0001">10.15479/AT:IST-2012-0001</a>.
  short: K. Chatterjee, S. Chaubal, P. Kamath, Faster Algorithms for Alternating Refinement
    Relations, IST Austria, 2012.
corr_author: '1'
date_created: 2018-12-12T11:38:59Z
date_published: 2012-07-04T00:00:00Z
date_updated: 2025-04-15T08:12:24Z
day: '04'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2012-0001
file:
- access_level: open_access
  checksum: ec8d1857cc7095d3de5107a0162ced37
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:28Z
  date_updated: 2020-07-14T12:46:39Z
  file_id: '5489'
  file_name: IST-2012-0001_IST-2012-0001.pdf
  file_size: 394256
  relation: main_file
file_date_updated: 2020-07-14T12:46:39Z
fulldoi: https://doi.org/10.15479/AT:IST-2012-0001
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '21'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '14'
related_material:
  record:
  - id: '497'
    relation: later_version
    status: public
status: public
title: Faster algorithms for alternating refinement relations
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '5396'
abstract:
- lang: eng
  text: We consider the problem of inference in agraphical model with binary variables.
    While in theory it is arguably preferable to compute marginal probabilities, in
    practice researchers often use MAP inference due to the availability of efficient
    discrete optimization algorithms. We bridge the gap between the two approaches
    by introducing the Discrete  Marginals technique in which approximate marginals
    are obtained by minimizing an objective function with unary and pair-wise terms
    over a discretized domain. This allows the use of techniques originally devel-oped
    for MAP-MRF inference and learning. We explore two ways to set up the objective
    function - by discretizing the Bethe free energy and by learning it  from training
    data. Experimental results show that for certain types of graphs a learned function
    can out-perform the  Bethe approximation. We also establish a link between the
    Bethe free energy and submodular functions.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Filip
  full_name: Korc, Filip
  id: 476A2FD6-F248-11E8-B48F-1D18A9856A87
  last_name: Korc
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Christoph
  full_name: Lampert, Christoph
  id: 40C20FD2-F248-11E8-B48F-1D18A9856A87
  last_name: Lampert
  orcid: 0000-0001-8622-7887
citation:
  ama: Korc F, Kolmogorov V, Lampert C. <i>Approximating Marginals Using Discrete
    Energy Minimization</i>. IST Austria; 2012. doi:<a href="https://doi.org/10.15479/AT:IST-2012-0003">10.15479/AT:IST-2012-0003</a>
  apa: Korc, F., Kolmogorov, V., &#38; Lampert, C. (2012). <i>Approximating marginals
    using discrete energy minimization</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2012-0003">https://doi.org/10.15479/AT:IST-2012-0003</a>
  chicago: Korc, Filip, Vladimir Kolmogorov, and Christoph Lampert. <i>Approximating
    Marginals Using Discrete Energy Minimization</i>. IST Austria, 2012. <a href="https://doi.org/10.15479/AT:IST-2012-0003">https://doi.org/10.15479/AT:IST-2012-0003</a>.
  ieee: F. Korc, V. Kolmogorov, and C. Lampert, <i>Approximating marginals using discrete
    energy minimization</i>. IST Austria, 2012.
  ista: Korc F, Kolmogorov V, Lampert C. 2012. Approximating marginals using discrete
    energy minimization, IST Austria, 13p.
  mla: Korc, Filip, et al. <i>Approximating Marginals Using Discrete Energy Minimization</i>.
    IST Austria, 2012, doi:<a href="https://doi.org/10.15479/AT:IST-2012-0003">10.15479/AT:IST-2012-0003</a>.
  short: F. Korc, V. Kolmogorov, C. Lampert, Approximating Marginals Using Discrete
    Energy Minimization, IST Austria, 2012.
date_created: 2018-12-12T11:39:06Z
date_published: 2012-07-23T00:00:00Z
date_updated: 2024-10-09T20:54:48Z
day: '23'
ddc:
- '000'
department:
- _id: VlKo
- _id: ChLa
doi: 10.15479/AT:IST-2012-0003
file:
- access_level: open_access
  checksum: 7e0ba85ad123b13223aaf6cdde2d288c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:29Z
  date_updated: 2020-07-14T12:46:44Z
  file_id: '5490'
  file_name: IST-2012-0003_IST-2012-0003.pdf
  file_size: 618744
  relation: main_file
file_date_updated: 2020-07-14T12:46:44Z
fulldoi: https://doi.org/10.15479/AT:IST-2012-0003
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '13'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '36'
related_material:
  record:
  - id: '3124'
    relation: earlier_version
    status: public
status: public
title: Approximating marginals using discrete energy minimization
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
OA_place: repository
_id: '5745'
abstract:
- lang: eng
  text: Unsatisfiability proofs find many applications in verification. Today, many
    SAT solvers are capable of producing resolution proofs of unsatisfiability. For
    efficiency smaller proofs are preferred over bigger ones. The solvers apply proof
    reduction methods to remove redundant parts of the proofs while and after generating
    the proofs. One method of reducing resolution proofs is redundant resolution reduction,
    i.e., removing repeated pivots in the paths of resolution proofs (aka Pivot recycle).
    The known single pass algorithm only tries to remove redundancies in the parts
    of the proof that are trees. In this paper, we present three modifications to
    improve the algorithm such that the redundancies can be found in the parts of
    the proofs that are DAGs. The first modified algorithm covers greater number of
    redundancies as compared to the known algorithm without incurring any additional
    cost. The second modified algorithm covers even greater number of the redundancies
    but it may have longer run times. Our third modified algorithm is parametrized
    and can trade off between run times and the coverage of the redundancies. We have
    implemented our algorithms in OpenSMT and applied them on unsatisfiability proofs
    of 198 examples from plain MUS track of SAT11 competition. The first and second
    algorithm additionally remove 0.89% and 10.57% of clauses respectively as compared
    to the original algorithm. For certain value of the parameter, the third algorithm
    removes almost as many clauses as the second algorithm but is significantly faster.
acknowledgement: "This work was supported by the ERC Advanced Investigator grant on
  Quantitative\r\nReactive Modeling (QUAREM)."
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ashutosh
  full_name: Gupta, Ashutosh
  id: 335E5684-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
citation:
  ama: 'Gupta A. Improved single pass algorithms for resolution proof reduction. In:
    <i>10th International Symposium on Automated Technology for Verification and Analysis</i>.
    Vol 7561. Springer Nature; 2012:107-121. doi:<a href="https://doi.org/10.1007/978-3-642-33386-6_10">10.1007/978-3-642-33386-6_10</a>'
  apa: 'Gupta, A. (2012). Improved single pass algorithms for resolution proof reduction.
    In <i>10th International Symposium on Automated Technology for Verification and
    Analysis</i> (Vol. 7561, pp. 107–121). Thiruvananthapuram, Kerala, India: Springer
    Nature. <a href="https://doi.org/10.1007/978-3-642-33386-6_10">https://doi.org/10.1007/978-3-642-33386-6_10</a>'
  chicago: Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof
    Reduction.” In <i>10th International Symposium on Automated Technology for Verification
    and Analysis</i>, 7561:107–21. Springer Nature, 2012. <a href="https://doi.org/10.1007/978-3-642-33386-6_10">https://doi.org/10.1007/978-3-642-33386-6_10</a>.
  ieee: A. Gupta, “Improved single pass algorithms for resolution proof reduction,”
    in <i>10th International Symposium on Automated Technology for Verification and
    Analysis</i>, Thiruvananthapuram, Kerala, India, 2012, vol. 7561, pp. 107–121.
  ista: 'Gupta A. 2012. Improved single pass algorithms for resolution proof reduction.
    10th International Symposium on Automated Technology for Verification and Analysis.
    ATVA: Automated Technology for Verification and Analysis, LNCS, vol. 7561, 107–121.'
  mla: Gupta, Ashutosh. “Improved Single Pass Algorithms for Resolution Proof Reduction.”
    <i>10th International Symposium on Automated Technology for Verification and Analysis</i>,
    vol. 7561, Springer Nature, 2012, pp. 107–21, doi:<a href="https://doi.org/10.1007/978-3-642-33386-6_10">10.1007/978-3-642-33386-6_10</a>.
  short: A. Gupta, in:, 10th International Symposium on Automated Technology for Verification
    and Analysis, Springer Nature, 2012, pp. 107–121.
conference:
  end_date: 2012-10-06
  location: Thiruvananthapuram, Kerala, India
  name: 'ATVA: Automated Technology for Verification and Analysis'
  start_date: 2012-10-03
corr_author: '1'
date_created: 2018-12-18T13:01:46Z
date_published: 2012-09-28T00:00:00Z
date_updated: 2025-04-15T07:56:27Z
day: '28'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-33386-6_10
ec_funded: 1
file:
- access_level: open_access
  checksum: 68415837a315de3cc4d120f6019d752c
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T13:07:35Z
  date_updated: 2020-07-14T12:47:10Z
  file_id: '5746'
  file_name: 2012_ATVA_Gupta.pdf
  file_size: 465502
  relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
fulldoi: https://doi.org/10.1007/978-3-642-33386-6_10
has_accepted_license: '1'
intvolume: '      7561'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 107-121
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
publication: 10th International Symposium on Automated Technology for Verification
  and Analysis
publication_identifier:
  eisbn:
  - '9783642333866'
  eissn:
  - 1611-3349
  isbn:
  - '9783642333859'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
pubrep_id: '180'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improved single pass algorithms for resolution proof reduction
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7561
year: '2012'
...
---
_id: '9451'
abstract:
- lang: eng
  text: The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes
    DNA demethylation before fertilization, but the targeting preferences, mechanism,
    and biological significance of this process remain unclear. Here, we show that
    active DNA demethylation mediated by the DEMETER DNA glycosylase accounts for
    all of the demethylation in the central cell and preferentially targets small,
    AT-rich, and nucleosome-depleted euchromatic transposable elements. The vegetative
    cell, the companion cell of sperm, also undergoes DEMETER-dependent demethylation
    of similar sequences, and lack of DEMETER in vegetative cells causes reduced small
    RNA–directed DNA methylation of transposons in sperm. Our results demonstrate
    that demethylation in companion cells reinforces transposon methylation in plant
    gametes and likely contributes to stable silencing of transposable elements across
    generations.
article_processing_charge: No
article_type: original
author:
- first_name: Christian A.
  full_name: Ibarra, Christian A.
  last_name: Ibarra
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  last_name: Feng
- first_name: Vera K.
  full_name: Schoft, Vera K.
  last_name: Schoft
- first_name: Tzung-Fu
  full_name: Hsieh, Tzung-Fu
  last_name: Hsieh
- first_name: Rie
  full_name: Uzawa, Rie
  last_name: Uzawa
- first_name: Jessica A.
  full_name: Rodrigues, Jessica A.
  last_name: Rodrigues
- first_name: Assaf
  full_name: Zemach, Assaf
  last_name: Zemach
- first_name: Nina
  full_name: Chumak, Nina
  last_name: Chumak
- first_name: Adriana
  full_name: Machlicova, Adriana
  last_name: Machlicova
- first_name: Toshiro
  full_name: Nishimura, Toshiro
  last_name: Nishimura
- first_name: Denisse
  full_name: Rojas, Denisse
  last_name: Rojas
- first_name: Robert L.
  full_name: Fischer, Robert L.
  last_name: Fischer
- first_name: Hisashi
  full_name: Tamaru, Hisashi
  last_name: Tamaru
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Ibarra CA, Feng X, Schoft VK, et al. Active DNA demethylation in plant companion
    cells reinforces transposon methylation in gametes. <i>Science</i>. 2012;337(6100):1360-1364.
    doi:<a href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>
  apa: Ibarra, C. A., Feng, X., Schoft, V. K., Hsieh, T.-F., Uzawa, R., Rodrigues,
    J. A., … Zilberman, D. (2012). Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes. <i>Science</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>
  chicago: Ibarra, Christian A., Xiaoqi Feng, Vera K. Schoft, Tzung-Fu Hsieh, Rie
    Uzawa, Jessica A. Rodrigues, Assaf Zemach, et al. “Active DNA Demethylation in
    Plant Companion Cells Reinforces Transposon Methylation in Gametes.” <i>Science</i>.
    American Association for the Advancement of Science, 2012. <a href="https://doi.org/10.1126/science.1224839">https://doi.org/10.1126/science.1224839</a>.
  ieee: C. A. Ibarra <i>et al.</i>, “Active DNA demethylation in plant companion cells
    reinforces transposon methylation in gametes,” <i>Science</i>, vol. 337, no. 6100.
    American Association for the Advancement of Science, pp. 1360–1364, 2012.
  ista: Ibarra CA, Feng X, Schoft VK, Hsieh T-F, Uzawa R, Rodrigues JA, Zemach A,
    Chumak N, Machlicova A, Nishimura T, Rojas D, Fischer RL, Tamaru H, Zilberman
    D. 2012. Active DNA demethylation in plant companion cells reinforces transposon
    methylation in gametes. Science. 337(6100), 1360–1364.
  mla: Ibarra, Christian A., et al. “Active DNA Demethylation in Plant Companion Cells
    Reinforces Transposon Methylation in Gametes.” <i>Science</i>, vol. 337, no. 6100,
    American Association for the Advancement of Science, 2012, pp. 1360–64, doi:<a
    href="https://doi.org/10.1126/science.1224839">10.1126/science.1224839</a>.
  short: C.A. Ibarra, X. Feng, V.K. Schoft, T.-F. Hsieh, R. Uzawa, J.A. Rodrigues,
    A. Zemach, N. Chumak, A. Machlicova, T. Nishimura, D. Rojas, R.L. Fischer, H.
    Tamaru, D. Zilberman, Science 337 (2012) 1360–1364.
date_created: 2021-06-04T07:51:31Z
date_published: 2012-09-14T00:00:00Z
date_updated: 2021-12-14T08:28:51Z
day: '14'
ddc:
- '580'
department:
- _id: DaZi
doi: 10.1126/science.1224839
extern: '1'
external_id:
  pmid:
  - '22984074'
fulldoi: https://doi.org/10.1126/science.1224839
has_accepted_license: '1'
intvolume: '       337'
issue: '6100'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034762/
month: '09'
oa: 1
oa_version: Published Version
page: 1360-1364
pmid: 1
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Active DNA demethylation in plant companion cells reinforces transposon methylation
  in gametes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 337
year: '2012'
...
---
_id: '9497'
abstract:
- lang: eng
  text: The regulation of eukaryotic chromatin relies on interactions between many
    epigenetic factors, including histone modifications, DNA methylation, and the
    incorporation of histone variants. H2A.Z, one of the most conserved but enigmatic
    histone variants that is enriched at the transcriptional start sites of genes,
    has been implicated in a variety of chromosomal processes. Recently, we reported
    a genome-wide anticorrelation between H2A.Z and DNA methylation, an epigenetic
    hallmark of heterochromatin that has also been found in the bodies of active genes
    in plants and animals. Here, we investigate the basis of this anticorrelation
    using a novel h2a.z loss-of-function line in Arabidopsis thaliana. Through genome-wide
    bisulfite sequencing, we demonstrate that loss of H2A.Z in Arabidopsis has only
    a minor effect on the level or profile of DNA methylation in genes, and we propose
    that the global anticorrelation between DNA methylation and H2A.Z is primarily
    caused by the exclusion of H2A.Z from methylated DNA. RNA sequencing and genomic
    mapping of H2A.Z show that H2A.Z enrichment across gene bodies, rather than at
    the TSS, is correlated with lower transcription levels and higher measures of
    gene responsiveness. Loss of H2A.Z causes misregulation of many genes that are
    disproportionately associated with response to environmental and developmental
    stimuli. We propose that H2A.Z deposition in gene bodies promotes variability
    in levels and patterns of gene expression, and that a major function of genic
    DNA methylation is to exclude H2A.Z from constitutively expressed genes.
article_number: e1002988
article_processing_charge: No
article_type: original
author:
- first_name: Devin
  full_name: Coleman-Derr, Devin
  last_name: Coleman-Derr
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Coleman-Derr D, Zilberman D. Deposition of histone variant H2A.Z within gene
    bodies regulates responsive genes. <i>PLoS Genetics</i>. 2012;8(10). doi:<a href="https://doi.org/10.1371/journal.pgen.1002988">10.1371/journal.pgen.1002988</a>
  apa: Coleman-Derr, D., &#38; Zilberman, D. (2012). Deposition of histone variant
    H2A.Z within gene bodies regulates responsive genes. <i>PLoS Genetics</i>. Public
    Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1002988">https://doi.org/10.1371/journal.pgen.1002988</a>
  chicago: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant
    H2A.Z within Gene Bodies Regulates Responsive Genes.” <i>PLoS Genetics</i>. Public
    Library of Science, 2012. <a href="https://doi.org/10.1371/journal.pgen.1002988">https://doi.org/10.1371/journal.pgen.1002988</a>.
  ieee: D. Coleman-Derr and D. Zilberman, “Deposition of histone variant H2A.Z within
    gene bodies regulates responsive genes,” <i>PLoS Genetics</i>, vol. 8, no. 10.
    Public Library of Science, 2012.
  ista: Coleman-Derr D, Zilberman D. 2012. Deposition of histone variant H2A.Z within
    gene bodies regulates responsive genes. PLoS Genetics. 8(10), e1002988.
  mla: Coleman-Derr, Devin, and Daniel Zilberman. “Deposition of Histone Variant H2A.Z
    within Gene Bodies Regulates Responsive Genes.” <i>PLoS Genetics</i>, vol. 8,
    no. 10, e1002988, Public Library of Science, 2012, doi:<a href="https://doi.org/10.1371/journal.pgen.1002988">10.1371/journal.pgen.1002988</a>.
  short: D. Coleman-Derr, D. Zilberman, PLoS Genetics 8 (2012).
date_created: 2021-06-07T10:55:27Z
date_published: 2012-10-11T00:00:00Z
date_updated: 2021-12-14T08:29:57Z
day: '11'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002988
extern: '1'
external_id:
  pmid:
  - '23071449'
fulldoi: https://doi.org/10.1371/journal.pgen.1002988
intvolume: '         8'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1371/journal.pgen.1002988
month: '10'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deposition of histone variant H2A.Z within gene bodies regulates responsive
  genes
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9499'
abstract:
- lang: eng
  text: EMBRYONIC FLOWER1 (EMF1) is a plant-specific gene crucial to Arabidopsis vegetative
    development. Loss of function mutants in the EMF1 gene mimic the phenotype caused
    by mutations in Polycomb Group protein (PcG) genes, which encode epigenetic repressors
    that regulate many aspects of eukaryotic development. In Arabidopsis, Polycomb
    Repressor Complex 2 (PRC2), made of PcG proteins, catalyzes trimethylation of
    lysine 27 on histone H3 (H3K27me3) and PRC1-like proteins catalyze H2AK119 ubiquitination.
    Despite functional similarity to PcG proteins, EMF1 lacks sequence homology with
    known PcG proteins; thus, its role in the PcG mechanism is unclear. To study the
    EMF1 functions and its mechanism of action, we performed genome-wide mapping of
    EMF1 binding and H3K27me3 modification sites in Arabidopsis seedlings. The EMF1
    binding pattern is similar to that of H3K27me3 modification on the chromosomal
    and genic level. ChIPOTLe peak finding and clustering analyses both show that
    the highly trimethylated genes also have high enrichment levels of EMF1 binding,
    termed EMF1_K27 genes. EMF1 interacts with regulatory genes, which are silenced
    to allow vegetative growth, and with genes specifying cell fates during growth
    and differentiation. H3K27me3 marks not only these genes but also some genes that
    are involved in endosperm development and maternal effects. Transcriptome analysis,
    coupled with the H3K27me3 pattern, of EMF1_K27 genes in emf1 and PRC2 mutants
    showed that EMF1 represses gene activities via diverse mechanisms and plays a
    novel role in the PcG mechanism.
article_number: e1002512
article_processing_charge: No
article_type: original
author:
- first_name: Sang Yeol
  full_name: Kim, Sang Yeol
  last_name: Kim
- first_name: Jungeun
  full_name: Lee, Jungeun
  last_name: Lee
- first_name: Leor
  full_name: Eshed-Williams, Leor
  last_name: Eshed-Williams
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
- first_name: Z. Renee
  full_name: Sung, Z. Renee
  last_name: Sung
citation:
  ama: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. EMF1 and PRC2 cooperate
    to repress key regulators of Arabidopsis development. <i>PLoS Genetics</i>. 2012;8(3).
    doi:<a href="https://doi.org/10.1371/journal.pgen.1002512">10.1371/journal.pgen.1002512</a>
  apa: Kim, S. Y., Lee, J., Eshed-Williams, L., Zilberman, D., &#38; Sung, Z. R. (2012).
    EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development.
    <i>PLoS Genetics</i>. Public Library of Science. <a href="https://doi.org/10.1371/journal.pgen.1002512">https://doi.org/10.1371/journal.pgen.1002512</a>
  chicago: Kim, Sang Yeol, Jungeun Lee, Leor Eshed-Williams, Daniel Zilberman, and
    Z. Renee Sung. “EMF1 and PRC2 Cooperate to Repress Key Regulators of Arabidopsis
    Development.” <i>PLoS Genetics</i>. Public Library of Science, 2012. <a href="https://doi.org/10.1371/journal.pgen.1002512">https://doi.org/10.1371/journal.pgen.1002512</a>.
  ieee: S. Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, and Z. R. Sung, “EMF1
    and PRC2 cooperate to repress key regulators of Arabidopsis development,” <i>PLoS
    Genetics</i>, vol. 8, no. 3. Public Library of Science, 2012.
  ista: Kim SY, Lee J, Eshed-Williams L, Zilberman D, Sung ZR. 2012. EMF1 and PRC2
    cooperate to repress key regulators of Arabidopsis development. PLoS Genetics.
    8(3), e1002512.
  mla: Kim, Sang Yeol, et al. “EMF1 and PRC2 Cooperate to Repress Key Regulators of
    Arabidopsis Development.” <i>PLoS Genetics</i>, vol. 8, no. 3, e1002512, Public
    Library of Science, 2012, doi:<a href="https://doi.org/10.1371/journal.pgen.1002512">10.1371/journal.pgen.1002512</a>.
  short: S.Y. Kim, J. Lee, L. Eshed-Williams, D. Zilberman, Z.R. Sung, PLoS Genetics
    8 (2012).
date_created: 2021-06-07T11:07:56Z
date_published: 2012-03-22T00:00:00Z
date_updated: 2021-12-14T08:31:14Z
day: '22'
department:
- _id: DaZi
doi: 10.1371/journal.pgen.1002512
extern: '1'
external_id:
  pmid:
  - '22457632'
fulldoi: https://doi.org/10.1371/journal.pgen.1002512
intvolume: '         8'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1371/journal.pgen.1002512
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Genetics
publication_identifier:
  eissn:
  - 1553-7404
  issn:
  - 1553-7390
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2012'
...
---
_id: '9528'
abstract:
- lang: eng
  text: Accumulating evidence points toward diverse functions for plant chromatin.
    Remarkable progress has been made over the last few years in elucidating the mechanisms
    for a number of these functions. Activity of the histone demethylase IBM1 accurately
    targets DNA methylation to silent repeats and transposable elements, not to genes.
    A genetic screen uncovered the surprising role of H2A.Z-containing nucleosomes
    in sensing precise differences in ambient temperature and consequent gene regulation.
    Precise maintenance of chromosome number is assured by a histone modification
    that suppresses inappropriate DNA replication and by centromeric histone H3 regulation
    of chromosome segregation. Histones and noncoding RNAs regulate FLOWERING LOCUS
    C, the expression of which quantitatively measures the duration of cold exposure,
    functioning as memory of winter. These findings are a testament to the power of
    using plants to research chromatin organization, and demonstrate examples of how
    chromatin functions to achieve biological accuracy, precision, and memory.
article_processing_charge: No
article_type: review
author:
- first_name: Jason T.
  full_name: Huff, Jason T.
  last_name: Huff
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Huff JT, Zilberman D. Regulation of biological accuracy, precision, and memory
    by plant chromatin organization. <i>Current Opinion in Genetics and Development</i>.
    2012;22(2):132-138. doi:<a href="https://doi.org/10.1016/j.gde.2012.01.007">10.1016/j.gde.2012.01.007</a>
  apa: Huff, J. T., &#38; Zilberman, D. (2012). Regulation of biological accuracy,
    precision, and memory by plant chromatin organization. <i>Current Opinion in Genetics
    and Development</i>. Elsevier. <a href="https://doi.org/10.1016/j.gde.2012.01.007">https://doi.org/10.1016/j.gde.2012.01.007</a>
  chicago: Huff, Jason T., and Daniel Zilberman. “Regulation of Biological Accuracy,
    Precision, and Memory by Plant Chromatin Organization.” <i>Current Opinion in
    Genetics and Development</i>. Elsevier, 2012. <a href="https://doi.org/10.1016/j.gde.2012.01.007">https://doi.org/10.1016/j.gde.2012.01.007</a>.
  ieee: J. T. Huff and D. Zilberman, “Regulation of biological accuracy, precision,
    and memory by plant chromatin organization,” <i>Current Opinion in Genetics and
    Development</i>, vol. 22, no. 2. Elsevier, pp. 132–138, 2012.
  ista: Huff JT, Zilberman D. 2012. Regulation of biological accuracy, precision,
    and memory by plant chromatin organization. Current Opinion in Genetics and Development.
    22(2), 132–138.
  mla: Huff, Jason T., and Daniel Zilberman. “Regulation of Biological Accuracy, Precision,
    and Memory by Plant Chromatin Organization.” <i>Current Opinion in Genetics and
    Development</i>, vol. 22, no. 2, Elsevier, 2012, pp. 132–38, doi:<a href="https://doi.org/10.1016/j.gde.2012.01.007">10.1016/j.gde.2012.01.007</a>.
  short: J.T. Huff, D. Zilberman, Current Opinion in Genetics and Development 22 (2012)
    132–138.
date_created: 2021-06-08T08:58:52Z
date_published: 2012-04-01T00:00:00Z
date_updated: 2021-12-14T08:32:38Z
department:
- _id: DaZi
doi: 10.1016/j.gde.2012.01.007
extern: '1'
external_id:
  pmid:
  - '22336527'
fulldoi: https://doi.org/10.1016/j.gde.2012.01.007
intvolume: '        22'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 132-138
pmid: 1
publication: Current Opinion in Genetics and Development
publication_identifier:
  issn:
  - 0959-437X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Regulation of biological accuracy, precision, and memory by plant chromatin
  organization
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 22
year: '2012'
...
---
_id: '9535'
abstract:
- lang: eng
  text: The most well-studied function of DNA methylation in eukaryotic cells is the
    transcriptional silencing of genes and transposons. More recent results showed
    that many eukaryotes methylate the bodies of genes as well and that this methylation
    correlates with transcriptional activity rather than repression. The purpose of
    gene body methylation remains mysterious, but is potentially related to the histone
    variant H2A.Z. Studies in plants and animals have shown that the genome-wide distributions
    of H2A.Z and DNA methylation are strikingly anticorrelated. Furthermore, we and
    other investigators have shown that this relationship is likely to be the result
    of an ancient but unknown mechanism by which DNA methylation prevents the incorporation
    of H2A.Z. Recently, we discovered strong correlations between the presence of
    H2A.Z within gene bodies, the degree to which a gene's expression varies across
    tissue types or environmental conditions, and transcriptional misregulation in
    an h2a.z mutant. We propose that one basal function of gene body methylation is
    the establishment of constitutive expression patterns within housekeeping genes
    by excluding H2A.Z from their bodies.
article_processing_charge: No
article_type: review
author:
- first_name: D.
  full_name: Coleman-Derr, D.
  last_name: Coleman-Derr
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Coleman-Derr D, Zilberman D. DNA methylation, H2A.Z, and the regulation of
    constitutive expression. <i>Cold Spring Harbor Symposia on Quantitative Biology</i>.
    2012;77:147-154. doi:<a href="https://doi.org/10.1101/sqb.2012.77.014944">10.1101/sqb.2012.77.014944</a>
  apa: Coleman-Derr, D., &#38; Zilberman, D. (2012). DNA methylation, H2A.Z, and the
    regulation of constitutive expression. <i>Cold Spring Harbor Symposia on Quantitative
    Biology</i>. Cold Spring Harbor Laboratory Press. <a href="https://doi.org/10.1101/sqb.2012.77.014944">https://doi.org/10.1101/sqb.2012.77.014944</a>
  chicago: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the
    Regulation of Constitutive Expression.” <i>Cold Spring Harbor Symposia on Quantitative
    Biology</i>. Cold Spring Harbor Laboratory Press, 2012. <a href="https://doi.org/10.1101/sqb.2012.77.014944">https://doi.org/10.1101/sqb.2012.77.014944</a>.
  ieee: D. Coleman-Derr and D. Zilberman, “DNA methylation, H2A.Z, and the regulation
    of constitutive expression,” <i>Cold Spring Harbor Symposia on Quantitative Biology</i>,
    vol. 77. Cold Spring Harbor Laboratory Press, pp. 147–154, 2012.
  ista: Coleman-Derr D, Zilberman D. 2012. DNA methylation, H2A.Z, and the regulation
    of constitutive expression. Cold Spring Harbor Symposia on Quantitative Biology.
    77, 147–154.
  mla: Coleman-Derr, D., and Daniel Zilberman. “DNA Methylation, H2A.Z, and the Regulation
    of Constitutive Expression.” <i>Cold Spring Harbor Symposia on Quantitative Biology</i>,
    vol. 77, Cold Spring Harbor Laboratory Press, 2012, pp. 147–54, doi:<a href="https://doi.org/10.1101/sqb.2012.77.014944">10.1101/sqb.2012.77.014944</a>.
  short: D. Coleman-Derr, D. Zilberman, Cold Spring Harbor Symposia on Quantitative
    Biology 77 (2012) 147–154.
date_created: 2021-06-08T13:01:23Z
date_published: 2012-12-18T00:00:00Z
date_updated: 2021-12-14T08:33:09Z
day: '18'
department:
- _id: DaZi
doi: 10.1101/sqb.2012.77.014944
extern: '1'
external_id:
  pmid:
  - '23250988'
fulldoi: https://doi.org/10.1101/sqb.2012.77.014944
intvolume: '        77'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/sqb.2012.77.014944
month: '12'
oa: 1
oa_version: Published Version
page: 147-154
pmid: 1
publication: Cold Spring Harbor Symposia on Quantitative Biology
publication_identifier:
  eissn:
  - 1943-4456
  issn:
  - 0091-7451
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: DNA methylation, H2A.Z, and the regulation of constitutive expression
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 77
year: '2012'
...
---
_id: '9755'
abstract:
- lang: eng
  text: Due to the omnipresent risk of epidemics, insect societies have evolved sophisticated
    disease defences at the individual and colony level. An intriguing yet little
    understood phenomenon is that social contact to pathogen-exposed individuals reduces
    susceptibility of previously naive nestmates to this pathogen. We tested whether
    such social immunisation in Lasius ants against the entomopathogenic fungus Metarhizium
    anisopliae is based on active upregulation of the immune system of nestmates following
    contact to an infectious individual or passive protection via transfer of immune
    effectors among group members—that is, active versus passive immunisation. We
    found no evidence for involvement of passive immunisation via transfer of antimicrobials
    among colony members. Instead, intensive allogrooming behaviour between naive
    and pathogen-exposed ants before fungal conidia firmly attached to their cuticle
    suggested passage of the pathogen from the exposed individuals to their nestmates.
    By tracing fluorescence-labelled conidia we indeed detected frequent pathogen
    transfer to the nestmates, where they caused low-level infections as revealed
    by growth of small numbers of fungal colony forming units from their dissected
    body content. These infections rarely led to death, but instead promoted an enhanced
    ability to inhibit fungal growth and an active upregulation of immune genes involved
    in antifungal defences (defensin and prophenoloxidase, PPO). Contrarily, there
    was no upregulation of the gene cathepsin L, which is associated with antibacterial
    and antiviral defences, and we found no increased antibacterial activity of nestmates
    of fungus-exposed ants. This indicates that social immunisation after fungal exposure
    is specific, similar to recent findings for individual-level immune priming in
    invertebrates. Epidemiological modeling further suggests that active social immunisation
    is adaptive, as it leads to faster elimination of the disease and lower death
    rates than passive immunisation. Interestingly, humans have also utilised the
    protective effect of low-level infections to fight smallpox by intentional transfer
    of low pathogen doses (“variolation” or “inoculation”).
article_processing_charge: No
author:
- first_name: Matthias
  full_name: Konrad, Matthias
  id: 46528076-F248-11E8-B48F-1D18A9856A87
  last_name: Konrad
- first_name: Meghan
  full_name: Vyleta, Meghan
  id: 418901AA-F248-11E8-B48F-1D18A9856A87
  last_name: Vyleta
- first_name: Fabian
  full_name: Theis, Fabian
  last_name: Theis
- first_name: Miriam
  full_name: Stock, Miriam
  id: 42462816-F248-11E8-B48F-1D18A9856A87
  last_name: Stock
- first_name: Martina
  full_name: Klatt, Martina
  id: E60F29C6-E9AE-11E9-AF6E-D190C7302F38
  last_name: Klatt
- first_name: Verena
  full_name: Drescher, Verena
  last_name: Drescher
- first_name: Carsten
  full_name: Marr, Carsten
  last_name: Marr
- first_name: Line V
  full_name: Ugelvig, Line V
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Konrad M, Vyleta M, Theis F, et al. Data from: Social transfer of pathogenic
    fungus promotes active immunisation in ant colonies. 2012. doi:<a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>'
  apa: 'Konrad, M., Vyleta, M., Theis, F., Stock, M., Klatt, M., Drescher, V., … Cremer,
    S. (2012). Data from: Social transfer of pathogenic fungus promotes active immunisation
    in ant colonies. Dryad. <a href="https://doi.org/10.5061/dryad.sv37s">https://doi.org/10.5061/dryad.sv37s</a>'
  chicago: 'Konrad, Matthias, Meghan Vyleta, Fabian Theis, Miriam Stock, Martina Klatt,
    Verena Drescher, Carsten Marr, Line V Ugelvig, and Sylvia Cremer. “Data from:
    Social Transfer of Pathogenic Fungus Promotes Active Immunisation in Ant Colonies.”
    Dryad, 2012. <a href="https://doi.org/10.5061/dryad.sv37s">https://doi.org/10.5061/dryad.sv37s</a>.'
  ieee: 'M. Konrad <i>et al.</i>, “Data from: Social transfer of pathogenic fungus
    promotes active immunisation in ant colonies.” Dryad, 2012.'
  ista: 'Konrad M, Vyleta M, Theis F, Stock M, Klatt M, Drescher V, Marr C, Ugelvig
    LV, Cremer S. 2012. Data from: Social transfer of pathogenic fungus promotes active
    immunisation in ant colonies, Dryad, <a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>.'
  mla: 'Konrad, Matthias, et al. <i>Data from: Social Transfer of Pathogenic Fungus
    Promotes Active Immunisation in Ant Colonies</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/dryad.sv37s">10.5061/dryad.sv37s</a>.'
  short: M. Konrad, M. Vyleta, F. Theis, M. Stock, M. Klatt, V. Drescher, C. Marr,
    L.V. Ugelvig, S. Cremer, (2012).
date_created: 2021-07-30T08:39:13Z
date_published: 2012-09-27T00:00:00Z
date_updated: 2025-09-30T07:50:00Z
day: '27'
department:
- _id: SyCr
doi: 10.5061/dryad.sv37s
fulldoi: https://doi.org/10.5061/dryad.sv37s
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.sv37s
month: '09'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '3242'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Social transfer of pathogenic fungus promotes active immunisation
  in ant colonies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...
---
_id: '9757'
abstract:
- lang: eng
  text: To fight infectious diseases, host immune defences are employed at multiple
    levels. Sanitary behaviour, such as pathogen avoidance and removal, acts as a
    first line of defence to prevent infection [1] before activation of the physiological
    immune system. Insect societies have evolved a wide range of collective hygiene
    measures and intensive health care towards pathogen-exposed group members [2].
    One of the most common behaviours is allogrooming, in which nestmates remove infectious
    particles from the body surfaces of exposed individuals [3]. Here we show that,
    in invasive garden ants, grooming of fungus-exposed brood is effective beyond
    the sheer mechanical removal of fungal conidiospores as it also includes chemical
    disinfection through the application of poison produced by the ants themselves.
    Formic acid is the main active component of the poison. It inhibits fungal growth
    of conidiospores remaining on the brood surface after grooming and also those
    collected in the mouth of the grooming ant. This dual function is achieved by
    uptake of the poison droplet into the mouth through acidopore self-grooming and
    subsequent application onto the infectious brood via brood grooming. This extraordinary
    behaviour extends current understanding of grooming and the establishment of social
    immunity in insect societies.
article_processing_charge: No
author:
- first_name: Simon
  full_name: Tragust, Simon
  id: 35A7A418-F248-11E8-B48F-1D18A9856A87
  last_name: Tragust
- first_name: Barbara
  full_name: Mitteregger, Barbara
  id: 479DDAAC-E9CD-11E9-9B5F-82450873F7A1
  last_name: Mitteregger
- first_name: Vanessa
  full_name: Barone, Vanessa
  id: 419EECCC-F248-11E8-B48F-1D18A9856A87
  last_name: Barone
  orcid: 0000-0003-2676-3367
- first_name: Matthias
  full_name: Konrad, Matthias
  id: 46528076-F248-11E8-B48F-1D18A9856A87
  last_name: Konrad
- first_name: Line V
  full_name: Ugelvig, Line V
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Tragust S, Mitteregger B, Barone V, Konrad M, Ugelvig LV, Cremer S. Data from:
    Ants disinfect fungus-exposed brood by oral uptake and spread of their poison.
    2012. doi:<a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>'
  apa: 'Tragust, S., Mitteregger, B., Barone, V., Konrad, M., Ugelvig, L. V., &#38;
    Cremer, S. (2012). Data from: Ants disinfect fungus-exposed brood by oral uptake
    and spread of their poison. Dryad. <a href="https://doi.org/10.5061/dryad.61649">https://doi.org/10.5061/dryad.61649</a>'
  chicago: 'Tragust, Simon, Barbara Mitteregger, Vanessa Barone, Matthias Konrad,
    Line V Ugelvig, and Sylvia Cremer. “Data from: Ants Disinfect Fungus-Exposed Brood
    by Oral Uptake and Spread of Their Poison.” Dryad, 2012. <a href="https://doi.org/10.5061/dryad.61649">https://doi.org/10.5061/dryad.61649</a>.'
  ieee: 'S. Tragust, B. Mitteregger, V. Barone, M. Konrad, L. V. Ugelvig, and S. Cremer,
    “Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of their
    poison.” Dryad, 2012.'
  ista: 'Tragust S, Mitteregger B, Barone V, Konrad M, Ugelvig LV, Cremer S. 2012.
    Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of their
    poison, Dryad, <a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>.'
  mla: 'Tragust, Simon, et al. <i>Data from: Ants Disinfect Fungus-Exposed Brood by
    Oral Uptake and Spread of Their Poison</i>. Dryad, 2012, doi:<a href="https://doi.org/10.5061/dryad.61649">10.5061/dryad.61649</a>.'
  short: S. Tragust, B. Mitteregger, V. Barone, M. Konrad, L.V. Ugelvig, S. Cremer,
    (2012).
date_created: 2021-07-30T12:31:31Z
date_published: 2012-12-14T00:00:00Z
date_updated: 2025-09-30T08:15:49Z
day: '14'
department:
- _id: SyCr
doi: 10.5061/dryad.61649
fulldoi: https://doi.org/10.5061/dryad.61649
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.61649
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '2926'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Ants disinfect fungus-exposed brood by oral uptake and spread of
  their poison'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2012'
...
