[{"citation":{"short":"N.N. Machnik, Algorithms for Causal Learning and Comparative Analysis for Genomic Data, Institute of Science and Technology Austria, 2024.","ama":"Machnik NN. Algorithms for causal learning and comparative analysis for genomic data. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:18642\">10.15479/at:ista:18642</a>","ieee":"N. N. Machnik, “Algorithms for causal learning and comparative analysis for genomic data,” Institute of Science and Technology Austria, 2024.","chicago":"Machnik, Nick N. “Algorithms for Causal Learning and Comparative Analysis for Genomic Data.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:18642\">https://doi.org/10.15479/at:ista:18642</a>.","apa":"Machnik, N. N. (2024). <i>Algorithms for causal learning and comparative analysis for genomic data</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:18642\">https://doi.org/10.15479/at:ista:18642</a>","mla":"Machnik, Nick N. <i>Algorithms for Causal Learning and Comparative Analysis for Genomic Data</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:18642\">10.15479/at:ista:18642</a>.","ista":"Machnik NN. 2024. Algorithms for causal learning and comparative analysis for genomic data. Institute of Science and Technology Austria."},"author":[{"full_name":"Machnik, Nick N","orcid":"0000-0001-6617-9742","id":"3591A0AA-F248-11E8-B48F-1D18A9856A87","first_name":"Nick N","last_name":"Machnik"}],"file_date_updated":"2025-06-12T22:30:02Z","type":"dissertation","publication_identifier":{"issn":["2663-337X"]},"acknowledgement":"I would like to thank the Swiss National Science Foundation for funding parts of this work\r\nthrough the Eccellenza Grant \"Improving estimation and prediction of common complex\r\ndisease risk\" with grant number PCEGP3_181181.","file":[{"access_level":"open_access","date_created":"2024-12-11T11:59:54Z","content_type":"application/pdf","checksum":"d45e4d170f9a70a1f69b44b99bd058e4","embargo":"2025-06-12","relation":"main_file","creator":"nmachnik","file_id":"18649","file_size":12845009,"file_name":"NickMachnikThesisFinal_pdfa_conv.pdf","date_updated":"2025-06-12T22:30:02Z"},{"checksum":"f88c9acc62002395ec4dcbdb5eea8b82","relation":"source_file","access_level":"closed","content_type":"application/zip","date_created":"2024-12-11T11:59:34Z","file_size":14189810,"file_name":"thesis.zip","date_updated":"2025-06-12T22:30:02Z","embargo_to":"open_access","creator":"nmachnik","file_id":"18650"}],"publisher":"Institute of Science and Technology Austria","supplementarymaterial":"unclear","researchdata_availability":"unclear","ddc":["576"],"oa":1,"language":[{"iso":"eng"}],"page":"138","department":[{"_id":"GradSch"},{"_id":"MaRo"}],"project":[{"grant_number":"PCEGP3_181181","_id":"9B8D11D6-BA93-11EA-9121-9846C619BF3A","name":"Improving estimation and prediction of common complex disease risk"}],"abstract":[{"lang":"eng","text":"This thesis consists of two pieces of work in the broader field of computational biology,\r\nboth of which are methods for the analysis of large scale biological data, implemented in\r\nefficient software.\r\nChapter 2 introduces a statistical software for causal discovery and inference from observed\r\ngenetic marker and phenotypic trait data. We explore in simulation how well the method\r\ncan fine-map genetic effects, find the correct causal structure among tens of traits and\r\nmillions of genetic markers, and infer the causal effect size for the discovered causal\r\nrelations. We then apply the method to 8 million markers and 17 traits from the UK\r\nBiobank and show that many relationships found with other methods are likely due to\r\nthe effects of hidden confounders.\r\nChapter 3 describes how this method can be applied to longitudinal data. I show how one\r\ncan incorporate the background knowledge present in the known order of measurements to\r\nimprove the accuracy of the causal discovery process, and explore the method’s ability to\r\nidentify age specific genetic effects, and how the error rates of this recovery are influenced\r\nby missing data due to different censoring mechanisms.\r\nChapter 4 introduces a statistical software for the comparison of chromatin contact maps\r\nbased on the structural similarity index. We explore the robustness of the method to\r\nnoise and size differences of the compared maps, show how it can measure evolutionary\r\nconservation of topological features by providing a similarity ranking of syntenic regions,\r\nand finally how it can detect alterations in 3D genome structure due to genetic mutations\r\nin samples of medical relevance.\r\n"}],"_id":"18642","oa_version":"Published Version","alternative_title":["ISTA Thesis"],"title":"Algorithms for causal learning and comparative analysis for genomic data","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","has_accepted_license":"1","degree_awarded":"PhD","OA_place":"publisher","related_material":{"record":[{"status":"public","id":"18648","relation":"part_of_dissertation"},{"id":"8707","relation":"part_of_dissertation","status":"public"}]},"day":"11","month":"12","status":"public","corr_author":"1","fulldoi":"https://doi.org/10.15479/at:ista:18642","doi":"10.15479/at:ista:18642","supervisor":[{"first_name":"Matthew Richard","orcid":"0000-0001-8982-8813","full_name":"Robinson, Matthew Richard","id":"E5D42276-F5DA-11E9-8E24-6303E6697425","last_name":"Robinson"}],"article_processing_charge":"No","year":"2024","publication_status":"published","date_created":"2024-12-10T13:49:15Z","doi_confirm":"1","date_updated":"2026-10-02T11:35:40Z","date_published":"2024-12-11T00:00:00Z"},{"alternative_title":["ISTA Thesis"],"oa_version":"Published Version","_id":"15101","ec_funded":1,"abstract":[{"lang":"eng","text":"The coupling between presynaptic Ca2+ channels and release sensors is a key factor that\r\ndetermines speed and efficacy of synapse transmission. At some excitatory synapses,\r\nchannel–sensor coupling becomes tighter during development, and tightening is often\r\nassociated with a switch in the reliance on different Ca2+ channel subtypes. However, the\r\ncoupling topography at many synapses remains unknown, and it is unclear how it changes\r\nduring development. To address this question, we analyzed the coupling configuration at the\r\ncerebellar basket cell (BC) to Purkinje cell (PC) synapse at different developmental stages,\r\ncombining biophysical analysis, structural analysis, and modeling.\r\nQuantal analysis of BC–PC indicated that release probability decreased, while the\r\nnumber of functional sites increased during development. Although transmitter release\r\npersistently relied on P/Q-type Ca2+ channels in the time period postnatal day 7–23, effects\r\nof the Ca2+ chelator EGTA and BAPTA applied by intracellular pipette perfusion decreased\r\nduring development, indicative of tightening of source-sensor coupling. Furthermore,\r\npresynaptic action potentials became shorter during development, suggesting reduced\r\nefficacy of Ca2+ channel activation.\r\nStructural analysis by freeze-fracture replica labeling (FRL) and transmission electron\r\nmicroscopy (EM) indicated that presynaptic P/Q-type Ca2+ channels formed nanoclusters\r\nthroughout development, whereas docked vesicles were only clustered at later\r\ndevelopmental stages. The number of functional release sites correlated better with the AZ\r\nnumber early in development, but match better with the Ca2+ channel cluster number at later\r\nstages.\r\nModeling suggested a developmental transformation from a more random to a more\r\nclustered coupling nanotopography. Thus, presynaptic signaling developmentally approaches\r\na point-to-point configuration, optimizing speed, reliability, and energy efficiency of synaptic\r\ntransmission."}],"project":[{"call_identifier":"H2020","name":"Biophysics and circuit function of a giant cortical glutamatergic synapse","grant_number":"692692","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425"},{"grant_number":"Z00312","_id":"25C5A090-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Synaptic communication in neuronal microcircuits"},{"grant_number":"P36232","_id":"bd88be38-d553-11ed-ba76-81d5a70a6ef5","name":"Mechanisms of GABA release in hippocampal circuits"},{"name":"Development of nanodomain coupling between Ca2+ channels and release sensors at a central inhibitory synapse","_id":"26B66A3E-B435-11E9-9278-68D0E5697425","grant_number":"25383"}],"department":[{"_id":"GradSch"},{"_id":"PeJo"}],"corr_author":"1","status":"public","month":"03","related_material":{"record":[{"status":"public","id":"14843","relation":"part_of_dissertation"}]},"day":"11","degree_awarded":"PhD","has_accepted_license":"1","OA_place":"publisher","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Developmental transformation of nanodomain coupling between Ca2+ channels and release sensors at a central GABAergic synapse","date_created":"2024-03-11T10:09:54Z","publication_status":"published","year":"2024","article_processing_charge":"No","supervisor":[{"last_name":"Jonas","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M"}],"doi":"10.15479/at:ista:15101","fulldoi":"https://doi.org/10.15479/at:ista:15101","date_published":"2024-03-11T00:00:00Z","date_updated":"2026-10-02T11:42:02Z","doi_confirm":"1","acknowledged_ssus":[{"_id":"EM-Fac"}],"file_date_updated":"2024-04-02T22:30:03Z","author":[{"last_name":"Chen","first_name":"JingJing","id":"2C4E65C8-F248-11E8-B48F-1D18A9856A87","full_name":"Chen, JingJing"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"citation":{"short":"J. Chen, Developmental Transformation of Nanodomain Coupling between Ca2+ Channels and Release Sensors at a Central GABAergic Synapse, Institute of Science and Technology Austria, 2024.","ieee":"J. Chen, “Developmental transformation of nanodomain coupling between Ca2+ channels and release sensors at a central GABAergic synapse,” Institute of Science and Technology Austria, 2024.","ama":"Chen J. Developmental transformation of nanodomain coupling between Ca2+ channels and release sensors at a central GABAergic synapse. 2024. doi:<a href=\"https://doi.org/10.15479/at:ista:15101\">10.15479/at:ista:15101</a>","chicago":"Chen, JingJing. “Developmental Transformation of Nanodomain Coupling between Ca2+ Channels and Release Sensors at a Central GABAergic Synapse.” Institute of Science and Technology Austria, 2024. <a href=\"https://doi.org/10.15479/at:ista:15101\">https://doi.org/10.15479/at:ista:15101</a>.","mla":"Chen, JingJing. <i>Developmental Transformation of Nanodomain Coupling between Ca2+ Channels and Release Sensors at a Central GABAergic Synapse</i>. Institute of Science and Technology Austria, 2024, doi:<a href=\"https://doi.org/10.15479/at:ista:15101\">10.15479/at:ista:15101</a>.","ista":"Chen J. 2024. Developmental transformation of nanodomain coupling between Ca2+ channels and release sensors at a central GABAergic synapse. Institute of Science and Technology Austria.","apa":"Chen, J. (2024). <i>Developmental transformation of nanodomain coupling between Ca2+ channels and release sensors at a central GABAergic synapse</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:15101\">https://doi.org/10.15479/at:ista:15101</a>"},"das_tickbox":"0","type":"dissertation","file":[{"access_level":"closed","date_created":"2024-03-11T14:10:58Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","checksum":"db4947474ffa271e66c254b6fe876a55","relation":"source_file","embargo_to":"open_access","file_id":"15104","creator":"jchen","file_size":11271363,"file_name":"Thesis_Jingjing CHEN.docx","date_updated":"2024-04-02T22:30:03Z"},{"file_size":16627311,"file_name":"Thesis_Jingjing CHEN_merged.pdf","date_updated":"2024-04-02T22:30:03Z","file_id":"15105","creator":"jchen","checksum":"a5eeae8b5702cd540f5d03469bc33dde","embargo":"2024-04-01","relation":"main_file","date_created":"2024-03-11T14:11:06Z","content_type":"application/pdf","access_level":"open_access"}],"publication_identifier":{"issn":["2663-337X"]},"page":"84","language":[{"iso":"eng"}],"oa":1,"researchdata_availability":"no","ddc":["570"],"publisher":"Institute of Science and Technology Austria","supplementarymaterial":"no"},{"doi":"10.1007/978-1-0716-3969-6_19","fulldoi":"https://doi.org/10.1007/978-1-0716-3969-6_19","article_processing_charge":"No","scopus_import":"1","year":"2024","date_created":"2024-08-13T12:16:41Z","publication_status":"published","intvolume":"      2831","quality_controlled":"1","date_updated":"2026-10-04T22:31:27Z","pmid":1,"publication":"Neuronal Morphogenesis","place":"New York, NY","date_published":"2024-08-13T00:00:00Z","department":[{"_id":"GradSch"},{"_id":"SiHi"}],"project":[{"_id":"34c9fbcb-11ca-11ed-8bc3-98fa5658610d","grant_number":"26253","name":"Molecular Mechanisms Regulating Cortical Neural Stem Cell Lineage Progression and Astrocyte Development"},{"name":"Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular Mechanisms of Neural Stem Cell Lineage Progression","_id":"059F6AB4-7A3F-11EA-A408-12923DDC885E","grant_number":"F7805"}],"oa_version":"None","_id":"17425","abstract":[{"lang":"eng","text":"Mosaic Analysis with Double Markers (MADM) is a powerful genetic method typically used for lineage tracing and to disentangle cell autonomous and tissue-wide roles of candidate genes with single cell resolution. Given the relatively sparse labeling, depending on which of the 19 MADM chromosomes one chooses, the MADM approach represents the perfect opportunity for cell morphology analysis. Various MADM studies include reports of morphological anomalies and phenotypes in the central nervous system (CNS). MADM for any candidate gene can easily incorporate morphological analysis within the experimental workflow. Here, we describe the methods of morphological cell analysis which we developed in the course of diverse recent MADM studies. This chapter will specifically focus on methods to quantify aspects of the morphology of neurons and astrocytes within the CNS, but these methods can broadly be applied to any MADM-labeled cells throughout the entire organism. We will cover two analyses—soma volume and dendrite characterization—of physical characteristics of pyramidal neurons in the somatosensory cortex, and two analyses—volume and Sholl analysis—of astrocyte morphology."}],"external_id":{"pmid":["39134857"]},"alternative_title":["Methods in Molecular Biology"],"editor":[{"last_name":"Toyooka","full_name":"Toyooka, Kazuhito","first_name":"Kazuhito"}],"user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers","status":"public","day":"13","related_material":{"record":[{"relation":"dissertation_contains","id":"20212","status":"public"}]},"month":"08","corr_author":"1","series_title":"MIMB","publication_identifier":{"eissn":["1940-6029"],"isbn":["9781071639689"],"issn":["1064-3745"],"eisbn":["9781071639696"]},"volume":2831,"acknowledgement":"We thank all Hippenmeyer lab members for support and discussions. This work was supported by the Scientific Service Units (SSU) at ISTA through resources provided by the Imaging & Optics Facility (IOF). O.A.M was a recipient of a DOC Fellowship (26253) of the Austrian Academy of Sciences. This work was supported by ISTA institutional funds, and The Austrian Science Fund Special Research Programmes (FWF SFB F78 Neuro Stem Modulation) to S.H.","publisher":"Springer Nature","supplementarymaterial":"yes","researchdata_availability":"no","language":[{"iso":"eng"}],"page":"283-299","citation":{"ieee":"O. Miranda, G. T. Cheung, and S. Hippenmeyer, “Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers,” in <i>Neuronal Morphogenesis</i>, 1st ed., vol. 2831, K. Toyooka, Ed. New York, NY: Springer Nature, 2024, pp. 283–299.","ama":"Miranda O, Cheung GT, Hippenmeyer S. Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers. In: Toyooka K, ed. <i>Neuronal Morphogenesis</i>. Vol 2831. 1st ed. MIMB. New York, NY: Springer Nature; 2024:283-299. doi:<a href=\"https://doi.org/10.1007/978-1-0716-3969-6_19\">10.1007/978-1-0716-3969-6_19</a>","short":"O. Miranda, G.T. Cheung, S. Hippenmeyer, in:, K. Toyooka (Ed.), Neuronal Morphogenesis, 1st ed., Springer Nature, New York, NY, 2024, pp. 283–299.","mla":"Miranda, Osvaldo, et al. “Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers.” <i>Neuronal Morphogenesis</i>, edited by Kazuhito Toyooka, 1st ed., vol. 2831, Springer Nature, 2024, pp. 283–99, doi:<a href=\"https://doi.org/10.1007/978-1-0716-3969-6_19\">10.1007/978-1-0716-3969-6_19</a>.","ista":"Miranda O, Cheung GT, Hippenmeyer S. 2024.Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers. In: Neuronal Morphogenesis. Methods in Molecular Biology, vol. 2831, 283–299.","apa":"Miranda, O., Cheung, G. T., &#38; Hippenmeyer, S. (2024). Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers. In K. Toyooka (Ed.), <i>Neuronal Morphogenesis</i> (1st ed., Vol. 2831, pp. 283–299). New York, NY: Springer Nature. <a href=\"https://doi.org/10.1007/978-1-0716-3969-6_19\">https://doi.org/10.1007/978-1-0716-3969-6_19</a>","chicago":"Miranda, Osvaldo, Giselle T Cheung, and Simon Hippenmeyer. “Morphological Analysis of Neurons and Glia Using Mosaic Analysis with Double Markers.” In <i>Neuronal Morphogenesis</i>, edited by Kazuhito Toyooka, 1st ed., 2831:283–99. MIMB. New York, NY: Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-1-0716-3969-6_19\">https://doi.org/10.1007/978-1-0716-3969-6_19</a>."},"author":[{"last_name":"Miranda","first_name":"Osvaldo","orcid":"0000-0001-6618-6889","full_name":"Miranda, Osvaldo","id":"862A3C56-A8BF-11E9-B4FA-D9E3E5697425"},{"last_name":"Cheung","id":"471195F6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8457-2572","full_name":"Cheung, Giselle T","first_name":"Giselle T"},{"full_name":"Hippenmeyer, Simon","orcid":"0000-0003-2279-1061","id":"37B36620-F248-11E8-B48F-1D18A9856A87","first_name":"Simon","last_name":"Hippenmeyer"}],"acknowledged_ssus":[{"_id":"Bio"}],"das_tickbox":"0","type":"book_chapter","edition":"1"},{"type":"journal_article","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2103.08268"}],"citation":{"ama":"Diao Y. Density of the union of positive diagonal binary quadratic forms. <i>Acta Arithmetica</i>. 2023;207:1-17. doi:<a href=\"https://doi.org/10.4064/aa210830-24-11\">10.4064/aa210830-24-11</a>","ieee":"Y. Diao, “Density of the union of positive diagonal binary quadratic forms,” <i>Acta Arithmetica</i>, vol. 207. Instytut Matematyczny, pp. 1–17, 2023.","short":"Y. Diao, Acta Arithmetica 207 (2023) 1–17.","apa":"Diao, Y. (2023). Density of the union of positive diagonal binary quadratic forms. <i>Acta Arithmetica</i>. Instytut Matematyczny. <a href=\"https://doi.org/10.4064/aa210830-24-11\">https://doi.org/10.4064/aa210830-24-11</a>","ista":"Diao Y. 2023. Density of the union of positive diagonal binary quadratic forms. Acta Arithmetica. 207, 1–17.","mla":"Diao, Yijie. “Density of the Union of Positive Diagonal Binary Quadratic Forms.” <i>Acta Arithmetica</i>, vol. 207, Instytut Matematyczny, 2023, pp. 1–17, doi:<a href=\"https://doi.org/10.4064/aa210830-24-11\">10.4064/aa210830-24-11</a>.","chicago":"Diao, Yijie. “Density of the Union of Positive Diagonal Binary Quadratic Forms.” <i>Acta Arithmetica</i>. Instytut Matematyczny, 2023. <a href=\"https://doi.org/10.4064/aa210830-24-11\">https://doi.org/10.4064/aa210830-24-11</a>."},"author":[{"full_name":"Diao, Yijie","orcid":"0000-0002-4989-5330","id":"7b7eb4ca-eb2c-11ec-b98b-accec0b20c3b","first_name":"Yijie","last_name":"Diao"}],"arxiv":1,"oa":1,"language":[{"iso":"eng"}],"page":"1-17","publisher":"Instytut Matematyczny","acknowledgement":"This article is a version the author’s master thesis at the University of Bonn. The author would like to thank his advisor Valentin Blomer for introducing the problem, and giving generous feedback and encouragement along the way, especially during the global pandemic.\r\nThe author thanks Edgar Assing for his lectures on analytic number theory. Finally, the author is grateful to the anonymous referees for their valuable time and comments.\r\n","publication_identifier":{"eissn":["1730-6264"],"issn":["0065-1036"]},"volume":207,"month":"01","day":"09","isi":1,"status":"public","corr_author":"1","keyword":["Algebra","Number Theory"],"title":"Density of the union of positive diagonal binary quadratic forms","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","external_id":{"isi":["000912903000001"],"arxiv":["2103.08268"]},"department":[{"_id":"GradSch"}],"_id":"12406","abstract":[{"lang":"eng","text":"Let X be a sufficiently large positive integer. We prove that one may choose a subset S of primes with cardinality O(logX) such that a positive proportion of integers less than X can be represented by x2+py2 for at least one p∈S."}],"oa_version":"Preprint","publication":"Acta Arithmetica","date_published":"2023-01-09T00:00:00Z","intvolume":"       207","quality_controlled":"1","date_updated":"2024-10-21T06:01:30Z","year":"2023","date_created":"2023-01-26T21:17:04Z","article_type":"original","publication_status":"published","fulldoi":"https://doi.org/10.4064/aa210830-24-11","doi":"10.4064/aa210830-24-11","article_processing_charge":"No","scopus_import":"1"},{"ddc":["000"],"publisher":"Springer Nature","page":"349-370","language":[{"iso":"eng"}],"oa":1,"arxiv":1,"volume":13992,"publication_identifier":{"issn":["0302-9743"],"eissn":["1611-3349"],"isbn":["9783031308284"]},"file":[{"file_id":"12468","creator":"esarac","success":1,"file_size":449027,"date_updated":"2023-01-31T07:22:21Z","file_name":"qsl.pdf","content_type":"application/pdf","access_level":"open_access","date_created":"2023-01-31T07:22:21Z","checksum":"981025aed580b6b27c426cb8856cf63e","relation":"main_file"},{"checksum":"f16e2af1e0eb243158ab0f0fe74e7d5a","relation":"main_file","content_type":"application/pdf","date_created":"2023-06-19T10:28:09Z","access_level":"open_access","file_size":1048171,"file_name":"2023_LNCS_HenzingerT.pdf","date_updated":"2023-06-19T10:28:09Z","creator":"dernst","file_id":"13153","success":1}],"acknowledgement":"We thank the anonymous reviewers for their helpful comments. This work was supported in part by the ERC-2020-AdG 101020093.","type":"conference","file_date_updated":"2023-06-19T10:28:09Z","author":[{"last_name":"Henzinger","first_name":"Thomas A","full_name":"Henzinger, Thomas A","orcid":"0000-0002-2985-7724","id":"40876CD8-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Mazzocchi","first_name":"Nicolas Adrien","full_name":"Mazzocchi, Nicolas Adrien","id":"b26baa86-3308-11ec-87b0-8990f34baa85"},{"last_name":"Sarac","first_name":"Naci E","id":"8C6B42F8-C8E6-11E9-A03A-F2DCE5697425","full_name":"Sarac, Naci E"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"conference":{"end_date":"2023-04-27","name":"FOSSACS: Foundations of Software Science and Computation Structures","start_date":"2023-04-22","location":"Paris, France"},"citation":{"ama":"Henzinger TA, Mazzocchi NA, Sarac NE. Quantitative safety and liveness. In: <i>26th International Conference Foundations of Software Science and Computation Structures</i>. Vol 13992. Springer Nature; 2023:349-370. doi:<a href=\"https://doi.org/10.1007/978-3-031-30829-1_17\">10.1007/978-3-031-30829-1_17</a>","ieee":"T. A. Henzinger, N. A. Mazzocchi, and N. E. Sarac, “Quantitative safety and liveness,” in <i>26th International Conference Foundations of Software Science and Computation Structures</i>, Paris, France, 2023, vol. 13992, pp. 349–370.","short":"T.A. Henzinger, N.A. Mazzocchi, N.E. Sarac, in:, 26th International Conference Foundations of Software Science and Computation Structures, Springer Nature, 2023, pp. 349–370.","mla":"Henzinger, Thomas A., et al. “Quantitative Safety and Liveness.” <i>26th International Conference Foundations of Software Science and Computation Structures</i>, vol. 13992, Springer Nature, 2023, pp. 349–70, doi:<a href=\"https://doi.org/10.1007/978-3-031-30829-1_17\">10.1007/978-3-031-30829-1_17</a>.","ista":"Henzinger TA, Mazzocchi NA, Sarac NE. 2023. Quantitative safety and liveness. 26th International Conference Foundations of Software Science and Computation Structures. FOSSACS: Foundations of Software Science and Computation Structures, LNCS, vol. 13992, 349–370.","apa":"Henzinger, T. A., Mazzocchi, N. A., &#38; Sarac, N. E. (2023). Quantitative safety and liveness. In <i>26th International Conference Foundations of Software Science and Computation Structures</i> (Vol. 13992, pp. 349–370). Paris, France: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-30829-1_17\">https://doi.org/10.1007/978-3-031-30829-1_17</a>","chicago":"Henzinger, Thomas A, Nicolas Adrien Mazzocchi, and Naci E Sarac. “Quantitative Safety and Liveness.” In <i>26th International Conference Foundations of Software Science and Computation Structures</i>, 13992:349–70. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/978-3-031-30829-1_17\">https://doi.org/10.1007/978-3-031-30829-1_17</a>."},"quality_controlled":"1","date_updated":"2025-09-09T12:21:08Z","intvolume":"     13992","date_published":"2023-04-21T00:00:00Z","publication":"26th International Conference Foundations of Software Science and Computation Structures","article_processing_charge":"No","scopus_import":"1","doi":"10.1007/978-3-031-30829-1_17","fulldoi":"https://doi.org/10.1007/978-3-031-30829-1_17","date_created":"2023-01-31T07:23:56Z","publication_status":"published","year":"2023","has_accepted_license":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Quantitative safety and liveness","corr_author":"1","status":"public","isi":1,"month":"04","day":"21","oa_version":"Published Version","_id":"12467","ec_funded":1,"abstract":[{"text":"Safety and liveness are elementary concepts of computation, and the foundation of many verification paradigms. The safety-liveness classification of boolean properties characterizes whether a given property can be falsified by observing a finite prefix of an infinite computation trace (always for safety, never for liveness). In quantitative specification and verification, properties assign not truth values, but quantitative values to infinite traces (e.g., a cost, or the distance to a boolean property). We introduce quantitative safety and liveness, and we prove that our definitions induce conservative quantitative generalizations of both (1)~the safety-progress hierarchy of boolean properties and (2)~the safety-liveness decomposition of boolean properties. In particular, we show that every quantitative property can be written as the pointwise minimum of a quantitative safety property and a quantitative liveness property. Consequently, like boolean properties, also quantitative properties can be min-decomposed into safety and liveness parts, or alternatively, max-decomposed into co-safety and co-liveness parts. Moreover, quantitative properties can be approximated naturally. We prove that every quantitative property that has both safe and co-safe approximations can be monitored arbitrarily precisely by a monitor that uses only a finite number of states.","lang":"eng"}],"department":[{"_id":"GradSch"},{"_id":"ToHe"}],"project":[{"_id":"62781420-2b32-11ec-9570-8d9b63373d4d","grant_number":"101020093","name":"Vigilant Algorithmic Monitoring of Software","call_identifier":"H2020"}],"alternative_title":["LNCS"],"external_id":{"arxiv":["2301.11175"],"isi":["001288609300017"]}},{"publisher":"Institute of Science and Technology Austria","date_updated":"2024-10-21T06:01:38Z","ddc":["572"],"oa":1,"date_published":"2023-03-23T00:00:00Z","fulldoi":"https://doi.org/10.15479/AT:ISTA:12497","doi":"10.15479/AT:ISTA:12497","article_processing_charge":"No","year":"2023","file":[{"checksum":"fd9a28620a81a82991fb70f4fd6591d9","relation":"main_file","date_created":"2023-03-23T10:03:16Z","access_level":"open_access","content_type":"application/zip","file_size":87018103,"date_updated":"2023-03-24T09:34:20Z","file_name":"Research_Data.zip","creator":"lbecker","file_id":"12743"},{"access_level":"open_access","date_created":"2023-03-24T07:13:55Z","content_type":"text/plain","checksum":"30ebdfb600af118fcf8518b6efe0b7e9","relation":"main_file","file_id":"12755","creator":"dernst","file_size":747,"file_name":"README.txt","date_updated":"2023-03-24T09:42:03Z"}],"date_created":"2023-02-03T08:08:02Z","title":"Research data to: The rigid core and flexible surface of amyloid fibrils probed by magic-angle-spinning NMR spectroscopy of aromatic residues","type":"research_data","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","has_accepted_license":"1","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"12675"}]},"day":"23","month":"03","status":"public","corr_author":"1","keyword":["aromatic side chains","isotopic labeling","protein dynamics","ring flips","spin relaxation"],"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","short":"CC BY-NC (4.0)","image":"/images/cc_by_nc.png"},"citation":{"short":"L.M. Becker, P. Schanda, (2023).","ama":"Becker LM, Schanda P. Research data to: The rigid core and flexible surface of amyloid fibrils probed by magic-angle-spinning NMR spectroscopy of aromatic residues. 2023. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12497\">10.15479/AT:ISTA:12497</a>","ieee":"L. M. Becker and P. Schanda, “Research data to: The rigid core and flexible surface of amyloid fibrils probed by magic-angle-spinning NMR spectroscopy of aromatic residues.” Institute of Science and Technology Austria, 2023.","chicago":"Becker, Lea Marie, and Paul Schanda. “Research Data to: The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic-Angle-Spinning NMR Spectroscopy of Aromatic Residues.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/AT:ISTA:12497\">https://doi.org/10.15479/AT:ISTA:12497</a>.","mla":"Becker, Lea Marie, and Paul Schanda. <i>Research Data to: The Rigid Core and Flexible Surface of Amyloid Fibrils Probed by Magic-Angle-Spinning NMR Spectroscopy of Aromatic Residues</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12497\">10.15479/AT:ISTA:12497</a>.","ista":"Becker LM, Schanda P. 2023. Research data to: The rigid core and flexible surface of amyloid fibrils probed by magic-angle-spinning NMR spectroscopy of aromatic residues, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:12497\">10.15479/AT:ISTA:12497</a>.","apa":"Becker, L. M., &#38; Schanda, P. (2023). Research data to: The rigid core and flexible surface of amyloid fibrils probed by magic-angle-spinning NMR spectroscopy of aromatic residues. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:12497\">https://doi.org/10.15479/AT:ISTA:12497</a>"},"department":[{"_id":"GradSch"},{"_id":"PaSc"}],"abstract":[{"text":"Aromatic side chains are important reporters of the plasticity of proteins, and often form important contacts in protein–protein interactions. We studied aromatic residues in the two structurally homologous cross-β amyloid fibrils HET-s, and  HELLF by employing a specific isotope-labeling approach and magic-angle-spinning NMR. The dynamic behavior of the aromatic residues Phe and Tyr indicates that the hydrophobic amyloid core is rigid, without any sign of \"breathing motions\" over hundreds of milliseconds at least. Aromatic residues exposed at the fibril surface have a rigid ring axis but undergo ring flips on a variety of time scales from nanoseconds to microseconds. Our approach provides direct insight into hydrophobic-core motions, enabling a better evaluation of the conformational heterogeneity generated from an NMR structural ensemble of such amyloid cross-β architecture.","lang":"eng"}],"_id":"12497","author":[{"first_name":"Lea Marie","orcid":"0000-0002-6401-5151","full_name":"Becker, Lea Marie","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","last_name":"Becker"},{"id":"7B541462-FAF6-11E9-A490-E8DFE5697425","full_name":"Schanda, Paul","orcid":"0000-0002-9350-7606","first_name":"Paul","last_name":"Schanda"}],"oa_version":"Published Version","file_date_updated":"2023-03-24T09:42:03Z","contributor":[{"contributor_type":"researcher","last_name":"Berbon","first_name":"Mélanie"},{"last_name":"Vallet","contributor_type":"researcher","first_name":"Alicia"},{"last_name":"Grelard","contributor_type":"researcher","first_name":"Axelle"},{"first_name":"Estelle","contributor_type":"researcher","last_name":"Morvan"},{"first_name":"Benjamin","contributor_type":"researcher","last_name":"Bardiaux"},{"last_name":"Lichtenecker","contributor_type":"researcher","first_name":"Roman"},{"last_name":"Ernst","contributor_type":"researcher","first_name":"Matthias"},{"first_name":"Antoine","contributor_type":"researcher","last_name":"Loquet"},{"contributor_type":"contact_person","last_name":"Schanda","first_name":"Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","orcid":"0000-0002-9350-7606"},{"contributor_type":"researcher","last_name":"Becker","first_name":"Lea Marie","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","orcid":"0000-0002-6401-5151"}]},{"article_type":"original","date_created":"2023-02-12T23:00:59Z","publication_status":"published","year":"2023","article_processing_charge":"No","scopus_import":"1","doi":"10.1103/PhysRevE.107.014608","fulldoi":"https://doi.org/10.1103/PhysRevE.107.014608","date_published":"2023-01-24T00:00:00Z","pmid":1,"publication":"Physical Review E","date_updated":"2025-03-06T14:01:47Z","quality_controlled":"1","intvolume":"       107","external_id":{"isi":["000963909800006"],"pmid":["36797971"],"arxiv":["2301.01856"]},"oa_version":"Preprint","_id":"12545","abstract":[{"lang":"eng","text":"We study active surface wetting using a minimal model of bacteria that takes into account the intrinsic motility diversity of living matter. A mixture of “fast” and “slow” self-propelled Brownian particles is considered in the presence of a wall. The evolution of the wetting layer thickness shows an overshoot before stationarity and its composition evolves in two stages, equilibrating after a slow elimination of excess particles. Nonmonotonic evolutions are shown to arise from delayed avalanches towards the dilute phase combined with the emergence of a transient particle front."}],"department":[{"_id":"GradSch"}],"status":"public","isi":1,"month":"01","day":"24","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Wetting dynamics by mixtures of fast and slow self-propelled particles","acknowledgement":"MR-V and RS are supported by Fondecyt Grant No. 1220536 and ANID – Millennium Science Initiative Program – NCN19 170D, Chile. PdC is supported by grant #2021/10139-2, Sao Paulo Research Foundation (FAPESP), Brazil.","volume":107,"publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"oa":1,"language":[{"iso":"eng"}],"arxiv":1,"publisher":"American Physical Society","author":[{"last_name":"Rojas Vega","first_name":"Mauricio Nicolas","full_name":"Rojas Vega, Mauricio Nicolas","id":"441e7207-f91f-11ec-b67c-9e6fe3d8fd6d"},{"full_name":"De Castro, Pablo","first_name":"Pablo","last_name":"De Castro"},{"last_name":"Soto","full_name":"Soto, Rodrigo","first_name":"Rodrigo"}],"citation":{"chicago":"Rojas Vega, Mauricio Nicolas, Pablo De Castro, and Rodrigo Soto. “Wetting Dynamics by Mixtures of Fast and Slow Self-Propelled Particles.” <i>Physical Review E</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/PhysRevE.107.014608\">https://doi.org/10.1103/PhysRevE.107.014608</a>.","apa":"Rojas Vega, M. N., De Castro, P., &#38; Soto, R. (2023). Wetting dynamics by mixtures of fast and slow self-propelled particles. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevE.107.014608\">https://doi.org/10.1103/PhysRevE.107.014608</a>","ista":"Rojas Vega MN, De Castro P, Soto R. 2023. Wetting dynamics by mixtures of fast and slow self-propelled particles. Physical Review E. 107(1), 014608.","mla":"Rojas Vega, Mauricio Nicolas, et al. “Wetting Dynamics by Mixtures of Fast and Slow Self-Propelled Particles.” <i>Physical Review E</i>, vol. 107, no. 1, 014608, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/PhysRevE.107.014608\">10.1103/PhysRevE.107.014608</a>.","short":"M.N. Rojas Vega, P. De Castro, R. Soto, Physical Review E 107 (2023).","ieee":"M. N. Rojas Vega, P. De Castro, and R. Soto, “Wetting dynamics by mixtures of fast and slow self-propelled particles,” <i>Physical Review E</i>, vol. 107, no. 1. American Physical Society, 2023.","ama":"Rojas Vega MN, De Castro P, Soto R. Wetting dynamics by mixtures of fast and slow self-propelled particles. <i>Physical Review E</i>. 2023;107(1). doi:<a href=\"https://doi.org/10.1103/PhysRevE.107.014608\">10.1103/PhysRevE.107.014608</a>"},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2301.01856","open_access":"1"}],"article_number":"014608","type":"journal_article","issue":"1"},{"date_created":"2023-02-24T12:20:47Z","publication_status":"published","year":"2023","article_processing_charge":"No","doi":"10.1137/1.9781611977554.ch173","fulldoi":"https://doi.org/10.1137/1.9781611977554.ch173","date_published":"2023-02-01T00:00:00Z","publication":"Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms","quality_controlled":"1","date_updated":"2026-06-18T17:28:38Z","oa_version":"Published Version","ec_funded":1,"_id":"12676","abstract":[{"text":"Turn-based stochastic games (aka simple stochastic games) are two-player zero-sum games played on directed graphs with probabilistic transitions. The goal of player-max is to maximize the probability to reach a target state against the adversarial player-min. These games lie in NP ∩ coNP and are among the rare combinatorial problems that belong to this complexity class for which the existence of polynomial-time algorithm is a major open question. While randomized sub-exponential time algorithm exists, all known deterministic algorithms require exponential time in the worst-case. An important open question has been whether faster algorithms can be obtained parametrized by the treewidth of the game graph. Even deterministic sub-exponential time algorithm for constant treewidth turn-based stochastic games has remain elusive. In this work our main result is a deterministic algorithm to solve turn-based stochastic games that, given a game with n states, treewidth at most t, and the bit-complexity of the probabilistic transition function log D, has running time O ((tn2 log D)t log n). In particular, our algorithm is quasi-polynomial time for games with constant or poly-logarithmic treewidth.","lang":"eng"}],"project":[{"call_identifier":"H2020","name":"Formal Methods for Stochastic Models: Algorithms and Applications","grant_number":"863818","_id":"0599E47C-7A3F-11EA-A408-12923DDC885E"}],"department":[{"_id":"GradSch"},{"_id":"KrCh"}],"corr_author":"1","status":"public","month":"02","day":"01","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Faster algorithm for turn-based stochastic games with bounded treewidth","acknowledgement":"This research was partially supported by the ERC CoG 863818 (ForM-SMArt) grant.","publication_identifier":{"isbn":["9781611977554"]},"page":"4590-4605","language":[{"iso":"eng"}],"oa":1,"ddc":["000"],"publisher":"Society for Industrial and Applied Mathematics","author":[{"first_name":"Krishnendu","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee"},{"last_name":"Meggendorfer","first_name":"Tobias","id":"b21b0c15-30a2-11eb-80dc-f13ca25802e1","full_name":"Meggendorfer, Tobias","orcid":"0000-0002-1712-2165"},{"last_name":"Saona Urmeneta","orcid":"0000-0001-5103-038X","full_name":"Saona Urmeneta, Raimundo J","id":"BD1DF4C4-D767-11E9-B658-BC13E6697425","first_name":"Raimundo J"},{"last_name":"Svoboda","full_name":"Svoboda, Jakub","orcid":"0000-0002-1419-3267","id":"130759D2-D7DD-11E9-87D2-DE0DE6697425","first_name":"Jakub"}],"conference":{"end_date":"2023-01-25","location":"Florence, Italy","start_date":"2023-01-22","name":"SODA: Symposium on Discrete Algorithms"},"citation":{"mla":"Chatterjee, Krishnendu, et al. “Faster Algorithm for Turn-Based Stochastic Games with Bounded Treewidth.” <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Society for Industrial and Applied Mathematics, 2023, pp. 4590–605, doi:<a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">10.1137/1.9781611977554.ch173</a>.","ista":"Chatterjee K, Meggendorfer T, Saona Urmeneta RJ, Svoboda J. 2023. Faster algorithm for turn-based stochastic games with bounded treewidth. Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 4590–4605.","apa":"Chatterjee, K., Meggendorfer, T., Saona Urmeneta, R. J., &#38; Svoboda, J. (2023). Faster algorithm for turn-based stochastic games with bounded treewidth. In <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i> (pp. 4590–4605). Florence, Italy: Society for Industrial and Applied Mathematics. <a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">https://doi.org/10.1137/1.9781611977554.ch173</a>","chicago":"Chatterjee, Krishnendu, Tobias Meggendorfer, Raimundo J Saona Urmeneta, and Jakub Svoboda. “Faster Algorithm for Turn-Based Stochastic Games with Bounded Treewidth.” In <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 4590–4605. Society for Industrial and Applied Mathematics, 2023. <a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">https://doi.org/10.1137/1.9781611977554.ch173</a>.","ama":"Chatterjee K, Meggendorfer T, Saona Urmeneta RJ, Svoboda J. Faster algorithm for turn-based stochastic games with bounded treewidth. In: <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>. Society for Industrial and Applied Mathematics; 2023:4590-4605. doi:<a href=\"https://doi.org/10.1137/1.9781611977554.ch173\">10.1137/1.9781611977554.ch173</a>","ieee":"K. Chatterjee, T. Meggendorfer, R. J. Saona Urmeneta, and J. Svoboda, “Faster algorithm for turn-based stochastic games with bounded treewidth,” in <i>Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms</i>, Florence, Italy, 2023, pp. 4590–4605.","short":"K. Chatterjee, T. Meggendorfer, R.J. Saona Urmeneta, J. Svoboda, in:, Proceedings of the 2023 Annual ACM-SIAM Symposium on Discrete Algorithms, Society for Industrial and Applied Mathematics, 2023, pp. 4590–4605."},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1137/1.9781611977554.ch173"}],"type":"conference"},{"external_id":{"arxiv":["2201.10892"],"isi":["001189844500001"]},"department":[{"_id":"UlWa"},{"_id":"GradSch"}],"abstract":[{"text":"The celebrated Erdős–Ko–Rado theorem about the maximal size of an intersecting family of r-element subsets of  was extended to the setting of exterior algebra in [5, Theorem 2.3] and in [6, Theorem 1.4]. However, the equality case has not been settled yet. In this short note, we show that the extension of the Erdős–Ko–Rado theorem and the characterization of the equality case therein, as well as those of the Hilton–Milner theorem to the setting of exterior algebra in the simplest non-trivial case of two-forms follow from a folklore puzzle about possible arrangements of an intersecting family of lines.","lang":"eng"}],"_id":"12680","oa_version":"Preprint","month":"06","day":"01","related_material":{"record":[{"status":"public","id":"13331","relation":"dissertation_contains"}]},"isi":1,"status":"public","corr_author":"1","title":"Erdős-Ko-Rado and Hilton-Milner theorems for two-forms","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","year":"2023","date_created":"2023-02-26T23:01:00Z","article_type":"letter_note","publication_status":"published","fulldoi":"https://doi.org/10.1016/j.disc.2023.113363","doi":"10.1016/j.disc.2023.113363","scopus_import":"1","article_processing_charge":"No","publication":"Discrete Mathematics","date_published":"2023-06-01T00:00:00Z","intvolume":"       346","date_updated":"2026-04-07T13:29:28Z","quality_controlled":"1","citation":{"short":"G. Ivanov, S. Köse, Discrete Mathematics 346 (2023).","ieee":"G. Ivanov and S. Köse, “Erdős-Ko-Rado and Hilton-Milner theorems for two-forms,” <i>Discrete Mathematics</i>, vol. 346, no. 6. Elsevier, 2023.","ama":"Ivanov G, Köse S. Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. <i>Discrete Mathematics</i>. 2023;346(6). doi:<a href=\"https://doi.org/10.1016/j.disc.2023.113363\">10.1016/j.disc.2023.113363</a>","chicago":"Ivanov, Grigory, and Seyda Köse. “Erdős-Ko-Rado and Hilton-Milner Theorems for Two-Forms.” <i>Discrete Mathematics</i>. Elsevier, 2023. <a href=\"https://doi.org/10.1016/j.disc.2023.113363\">https://doi.org/10.1016/j.disc.2023.113363</a>.","apa":"Ivanov, G., &#38; Köse, S. (2023). Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. <i>Discrete Mathematics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.disc.2023.113363\">https://doi.org/10.1016/j.disc.2023.113363</a>","mla":"Ivanov, Grigory, and Seyda Köse. “Erdős-Ko-Rado and Hilton-Milner Theorems for Two-Forms.” <i>Discrete Mathematics</i>, vol. 346, no. 6, 113363, Elsevier, 2023, doi:<a href=\"https://doi.org/10.1016/j.disc.2023.113363\">10.1016/j.disc.2023.113363</a>.","ista":"Ivanov G, Köse S. 2023. Erdős-Ko-Rado and Hilton-Milner theorems for two-forms. Discrete Mathematics. 346(6), 113363."},"author":[{"last_name":"Ivanov","first_name":"Grigory","orcid":"0000-0002-5021-3982","full_name":"Ivanov, Grigory","id":"87744F66-5C6F-11EA-AFE0-D16B3DDC885E"},{"last_name":"Köse","orcid":"0009-0008-0457-9730","full_name":"Köse, Seyda","id":"8ba3170d-dc85-11ea-9058-c4251c96a6eb","first_name":"Seyda"}],"type":"journal_article","issue":"6","article_number":"113363","main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2201.10892","open_access":"1"}],"publication_identifier":{"issn":["0012-365X"]},"volume":346,"arxiv":1,"oa":1,"language":[{"iso":"eng"}],"publisher":"Elsevier"},{"alternative_title":["ISTA Thesis"],"department":[{"_id":"GradSch"},{"_id":"MaJö"}],"project":[{"call_identifier":"H2020","name":"Circuits of Visual Attention","grant_number":"756502","_id":"2634E9D2-B435-11E9-9278-68D0E5697425"}],"ec_funded":1,"_id":"12716","abstract":[{"text":"The process of detecting and evaluating sensory information to guide behaviour is termed perceptual decision-making (PDM), and is critical for the ability of an organism to interact with its external world. Individuals with autism, a neurodevelopmental condition primarily characterised by social and communication difficulties, frequently exhibit altered sensory processing and PDM difficulties are widely reported. Recent technological advancements have pushed forward our understanding of the genetic changes accompanying this condition, however our understanding of how these mutations affect the function of specific neuronal circuits and bring about the corresponding behavioural changes remains limited. Here, we use an innate PDM task, the looming avoidance response (LAR) paradigm, to identify a convergent behavioural abnormality across three molecularly distinct genetic mouse models of autism (Cul3, Setd5 and Ptchd1). Although mutant mice can rapidly detect threatening visual stimuli, their responses are consistently delayed, requiring longer to initiate an appropriate response than their wild-type siblings. Mutant animals show abnormal adaptation in both their stimulus- evoked escape responses and exploratory dynamics following repeated stimulus presentations. Similarly delayed behavioural responses are observed in wild-type animals when faced with more ambiguous threats, suggesting the mutant phenotype could arise from a dysfunction in the flexible control of this PDM process.\r\nOur knowledge of the core neuronal circuitry mediating the LAR facilitated a detailed dissection of the neuronal mechanisms underlying the behavioural impairment. In vivo extracellular recording revealed that visual responses were unaffected within a key brain region for the rapid processing of visual threats, the superior colliculus (SC), indicating that the behavioural delay was unlikely to originate from sensory impairments. Delayed behavioural responses were recapitulated in the Setd5 model following optogenetic stimulation of the excitatory output neurons of the SC, which are known to mediate escape initiation through the activation of cells in the underlying dorsal periaqueductal grey (dPAG). In vitro patch-clamp recordings of dPAG cells uncovered a stark hypoexcitability phenotype in two out of the three genetic models investigated (Setd5 and Ptchd1), that in Setd5, is mediated by the misregulation of voltage-gated potassium channels. Overall, our results show that the ability to use visual information to drive efficient escape responses is impaired in three diverse genetic mouse models of autism and that, in one of the models studied, this behavioural delay likely originates from differences in the intrinsic excitability of a key subcortical node, the dPAG. Furthermore, this work showcases the use of an innate behavioural paradigm to mechanistically dissect PDM processes in autism.","lang":"eng"}],"oa_version":"Published Version","day":"10","month":"03","status":"public","corr_author":"1","title":"To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","OA_place":"publisher","degree_awarded":"PhD","has_accepted_license":"1","year":"2023","publication_status":"published","date_created":"2023-03-08T15:19:45Z","fulldoi":"https://doi.org/10.15479/at:ista:12716","doi":"10.15479/at:ista:12716","supervisor":[{"last_name":"Jösch","full_name":"Jösch, Maximilian A","orcid":"0000-0002-3937-1330","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","first_name":"Maximilian A"}],"article_processing_charge":"No","date_published":"2023-03-10T00:00:00Z","date_updated":"2026-04-07T13:25:15Z","acknowledged_ssus":[{"_id":"PreCl"},{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"M-Shop"},{"_id":"CampIT"}],"citation":{"ama":"Burnett L. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>","ieee":"L. Burnett, “To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism,” Institute of Science and Technology Austria, 2023.","short":"L. Burnett, To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism, Institute of Science and Technology Austria, 2023.","mla":"Burnett, Laura. <i>To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12716\">10.15479/at:ista:12716</a>.","ista":"Burnett L. 2023. To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism. Institute of Science and Technology Austria.","apa":"Burnett, L. (2023). <i>To flee, or not to flee? Using innate defensive behaviours to investigate rapid perceptual decision-making through subcortical circuits in mouse models of autism</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>","chicago":"Burnett, Laura. “To Flee, or Not to Flee? Using Innate Defensive Behaviours to Investigate Rapid Perceptual Decision-Making through Subcortical Circuits in Mouse Models of Autism.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12716\">https://doi.org/10.15479/at:ista:12716</a>."},"author":[{"last_name":"Burnett","orcid":"0000-0002-8937-410X","full_name":"Burnett, Laura","id":"3B717F68-F248-11E8-B48F-1D18A9856A87","first_name":"Laura"}],"file_date_updated":"2023-03-08T15:08:46Z","type":"dissertation","file":[{"file_size":23029260,"date_updated":"2023-03-08T15:08:46Z","file_name":"Burnett_Thesis_2023.docx","file_id":"12717","creator":"lburnett","checksum":"6c6d9cc2c4cdacb74e6b1047a34d7332","relation":"source_file","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","date_created":"2023-03-08T15:08:46Z"},{"file_size":11959869,"file_name":"Burnett_Thesis_2023_pdfA.pdf","date_updated":"2023-03-08T15:08:46Z","creator":"lburnett","file_id":"12718","success":1,"checksum":"cebc77705288bf4382db9b3541483cd0","relation":"main_file","date_created":"2023-03-08T15:08:46Z","access_level":"open_access","content_type":"application/pdf"}],"publication_identifier":{"issn":["2663-337X"]},"language":[{"iso":"eng"}],"oa":1,"page":"178","publisher":"Institute of Science and Technology Austria","ddc":["599","573"]},{"oa_version":"Preprint","abstract":[{"text":"Lead halide perovskites enjoy a number of remarkable optoelectronic properties. To explain their origin, it is necessary to study how electromagnetic fields interact with these systems. We address this problem here by studying two classical quantities: Faraday rotation and the complex refractive index in a paradigmatic perovskite CH3NH3PbBr3 in a broad wavelength range. We find that the minimal coupling of electromagnetic fields to the k⋅p Hamiltonian is insufficient to describe the observed data even on the qualitative level. To amend this, we demonstrate that there exists a relevant atomic-level coupling between electromagnetic fields and the spin degree of freedom. This spin-electric coupling allows for quantitative description of a number of previous as well as present experimental data. In particular, we use it here to show that the Faraday effect in lead halide perovskites is dominated by the Zeeman splitting of the energy levels and has a substantial beyond-Becquerel contribution. Finally, we present general symmetry-based phenomenological arguments that in the low-energy limit our effective model includes all basis coupling terms to the electromagnetic field in the linear order.","lang":"eng"}],"_id":"12723","department":[{"_id":"GradSch"},{"_id":"ZhAl"},{"_id":"MiLe"}],"external_id":{"pmid":["36962044"],"isi":["000982435900002"],"arxiv":["2203.09443"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","title":"Spin-electric coupling in lead halide perovskites","keyword":["General Physics and Astronomy"],"corr_author":"1","isi":1,"status":"public","day":"10","month":"03","article_processing_charge":"No","scopus_import":"1","doi":"10.1103/physrevlett.130.106901","fulldoi":"https://doi.org/10.1103/physrevlett.130.106901","article_type":"original","date_created":"2023-03-14T13:11:59Z","publication_status":"published","year":"2023","date_updated":"2025-04-23T08:53:33Z","quality_controlled":"1","intvolume":"       130","date_published":"2023-03-10T00:00:00Z","pmid":1,"publication":"Physical Review Letters","author":[{"last_name":"Volosniev","first_name":"Artem","id":"37D278BC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0393-5525","full_name":"Volosniev, Artem"},{"full_name":"Shiva Kumar, Abhishek","id":"5e9a6931-eb97-11eb-a6c2-e96f7058d77a","first_name":"Abhishek","last_name":"Shiva Kumar"},{"last_name":"Lorenc","full_name":"Lorenc, Dusan","id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87","first_name":"Dusan"},{"last_name":"Ashourishokri","first_name":"Younes","full_name":"Ashourishokri, Younes","id":"e32c111f-f6e0-11ea-865d-eb955baea334"},{"full_name":"Zhumekenov, Ayan A.","first_name":"Ayan A.","last_name":"Zhumekenov"},{"last_name":"Bakr","full_name":"Bakr, Osman M.","first_name":"Osman M."},{"first_name":"Mikhail","orcid":"0000-0002-6990-7802","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","last_name":"Lemeshko"},{"id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","full_name":"Alpichshev, Zhanybek","orcid":"0000-0002-7183-5203","first_name":"Zhanybek","last_name":"Alpichshev"}],"citation":{"ieee":"A. Volosniev <i>et al.</i>, “Spin-electric coupling in lead halide perovskites,” <i>Physical Review Letters</i>, vol. 130, no. 10. American Physical Society, 2023.","ama":"Volosniev A, Shiva Kumar A, Lorenc D, et al. Spin-electric coupling in lead halide perovskites. <i>Physical Review Letters</i>. 2023;130(10). doi:<a href=\"https://doi.org/10.1103/physrevlett.130.106901\">10.1103/physrevlett.130.106901</a>","short":"A. Volosniev, A. Shiva Kumar, D. Lorenc, Y. Ashourishokri, A.A. Zhumekenov, O.M. Bakr, M. Lemeshko, Z. Alpichshev, Physical Review Letters 130 (2023).","mla":"Volosniev, Artem, et al. “Spin-Electric Coupling in Lead Halide Perovskites.” <i>Physical Review Letters</i>, vol. 130, no. 10, 106901, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/physrevlett.130.106901\">10.1103/physrevlett.130.106901</a>.","ista":"Volosniev A, Shiva Kumar A, Lorenc D, Ashourishokri Y, Zhumekenov AA, Bakr OM, Lemeshko M, Alpichshev Z. 2023. Spin-electric coupling in lead halide perovskites. Physical Review Letters. 130(10), 106901.","apa":"Volosniev, A., Shiva Kumar, A., Lorenc, D., Ashourishokri, Y., Zhumekenov, A. A., Bakr, O. M., … Alpichshev, Z. (2023). Spin-electric coupling in lead halide perovskites. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevlett.130.106901\">https://doi.org/10.1103/physrevlett.130.106901</a>","chicago":"Volosniev, Artem, Abhishek Shiva Kumar, Dusan Lorenc, Younes Ashourishokri, Ayan A. Zhumekenov, Osman M. Bakr, Mikhail Lemeshko, and Zhanybek Alpichshev. “Spin-Electric Coupling in Lead Halide Perovskites.” <i>Physical Review Letters</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/physrevlett.130.106901\">https://doi.org/10.1103/physrevlett.130.106901</a>."},"main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2203.09443","open_access":"1"}],"article_number":"106901","type":"journal_article","issue":"10","volume":130,"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"publisher":"American Physical Society","oa":1,"language":[{"iso":"eng"}],"arxiv":1},{"article_processing_charge":"No","scopus_import":"1","fulldoi":"https://doi.org/10.1103/physrevb.107.125201","doi":"10.1103/physrevb.107.125201","date_created":"2023-03-14T13:13:05Z","publication_status":"published","article_type":"original","year":"2023","quality_controlled":"1","date_updated":"2024-10-09T21:04:46Z","intvolume":"       107","date_published":"2023-03-15T00:00:00Z","publication":"Physical Review B","abstract":[{"lang":"eng","text":"We use general symmetry-based arguments to construct an effective model suitable for studying optical properties of lead halide perovskites. To build the model, we identify an atomic-level interaction between electromagnetic fields and the spin degree of freedom that should be added to a minimally coupled k⋅p Hamiltonian. As a first application, we study two basic optical characteristics of the material: the Verdet constant and the refractive index. Beyond these linear characteristics of the material, the model is suitable for calculating nonlinear effects such as the third-order optical susceptibility. Analysis of this quantity shows that the geometrical properties of the spin-electric term imply isotropic optical response of the system, and that optical anisotropy of lead halide perovskites is a manifestation of hopping of charge carriers. To illustrate this, we discuss third-harmonic generation."}],"_id":"12724","oa_version":"Preprint","department":[{"_id":"GradSch"},{"_id":"ZhAl"},{"_id":"MiLe"}],"external_id":{"arxiv":["2204.04022"],"isi":["000972602200006"]},"title":"Effective model for studying optical properties of lead halide perovskites","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","corr_author":"1","month":"03","day":"15","isi":1,"status":"public","volume":107,"publication_identifier":{"issn":["2469-9950"],"eissn":["2469-9969"]},"publisher":"American Physical Society","arxiv":1,"language":[{"iso":"eng"}],"oa":1,"author":[{"first_name":"Artem","id":"37D278BC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-0393-5525","full_name":"Volosniev, Artem","last_name":"Volosniev"},{"last_name":"Shiva Kumar","id":"5e9a6931-eb97-11eb-a6c2-e96f7058d77a","full_name":"Shiva Kumar, Abhishek","first_name":"Abhishek"},{"last_name":"Lorenc","id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87","full_name":"Lorenc, Dusan","first_name":"Dusan"},{"full_name":"Ashourishokri, Younes","id":"e32c111f-f6e0-11ea-865d-eb955baea334","first_name":"Younes","last_name":"Ashourishokri"},{"first_name":"Ayan","full_name":"Zhumekenov, Ayan","last_name":"Zhumekenov"},{"full_name":"Bakr, Osman M.","first_name":"Osman M.","last_name":"Bakr"},{"last_name":"Lemeshko","first_name":"Mikhail","orcid":"0000-0002-6990-7802","full_name":"Lemeshko, Mikhail","id":"37CB05FA-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Alpichshev","full_name":"Alpichshev, Zhanybek","orcid":"0000-0002-7183-5203","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","first_name":"Zhanybek"}],"citation":{"short":"A. Volosniev, A. Shiva Kumar, D. Lorenc, Y. Ashourishokri, A. Zhumekenov, O.M. Bakr, M. Lemeshko, Z. Alpichshev, Physical Review B 107 (2023).","ama":"Volosniev A, Shiva Kumar A, Lorenc D, et al. Effective model for studying optical properties of lead halide perovskites. <i>Physical Review B</i>. 2023;107(12). doi:<a href=\"https://doi.org/10.1103/physrevb.107.125201\">10.1103/physrevb.107.125201</a>","ieee":"A. Volosniev <i>et al.</i>, “Effective model for studying optical properties of lead halide perovskites,” <i>Physical Review B</i>, vol. 107, no. 12. American Physical Society, 2023.","chicago":"Volosniev, Artem, Abhishek Shiva Kumar, Dusan Lorenc, Younes Ashourishokri, Ayan Zhumekenov, Osman M. Bakr, Mikhail Lemeshko, and Zhanybek Alpichshev. “Effective Model for Studying Optical Properties of Lead Halide Perovskites.” <i>Physical Review B</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/physrevb.107.125201\">https://doi.org/10.1103/physrevb.107.125201</a>.","apa":"Volosniev, A., Shiva Kumar, A., Lorenc, D., Ashourishokri, Y., Zhumekenov, A., Bakr, O. M., … Alpichshev, Z. (2023). Effective model for studying optical properties of lead halide perovskites. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevb.107.125201\">https://doi.org/10.1103/physrevb.107.125201</a>","ista":"Volosniev A, Shiva Kumar A, Lorenc D, Ashourishokri Y, Zhumekenov A, Bakr OM, Lemeshko M, Alpichshev Z. 2023. Effective model for studying optical properties of lead halide perovskites. Physical Review B. 107(12), 125201.","mla":"Volosniev, Artem, et al. “Effective Model for Studying Optical Properties of Lead Halide Perovskites.” <i>Physical Review B</i>, vol. 107, no. 12, 125201, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/physrevb.107.125201\">10.1103/physrevb.107.125201</a>."},"article_number":"125201","main_file_link":[{"url":"https://doi.org/10.48550/arXiv.2204.04022","open_access":"1"}],"issue":"12","type":"journal_article"},{"department":[{"_id":"GradSch"},{"_id":"BjHo"}],"oa_version":"None","abstract":[{"lang":"eng","text":"Most motions of many-body systems at any scale in nature with sufficient degrees\r\nof freedom tend to be chaotic; reaching from the orbital motion of planets, the air\r\ncurrents in our atmosphere, down to the water flowing through our pipelines or\r\nthe movement of a population of bacteria. To the observer it is therefore intriguing\r\nwhen a moving collective exhibits order. Collective motion of flocks of birds, schools\r\nof fish or swarms of self-propelled particles or robots have been studied extensively\r\nover the past decades but the mechanisms involved in the transition from chaos to\r\norder remain unclear. Here, the interactions, that in most systems give rise to chaos,\r\nsustain order. In this thesis we investigate mechanisms that preserve, destabilize\r\nor lead to the ordered state. We show that endothelial cells migrating in circular\r\nconfinements transition to a collective rotating state and concomitantly synchronize\r\nthe frequencies of nucleating actin waves within individual cells. Consequently,\r\nthe frequency dependent cell migration speed uniformizes across the population.\r\nComplementary to the WAVE dependent nucleation of traveling actin waves, we\r\nshow that in leukocytes the actin polymerization depending on WASp generates\r\npushing forces locally at stationary patches. Next, in pipe flows, we study methods\r\nto disrupt the self–sustaining cycle of turbulence and therefore relaminarize the\r\nflow. While we find in pulsating flow conditions that turbulence emerges through a\r\nhelical instability during the decelerating phase. Finally, we show quantitatively in\r\nbrain slices of mice that wild-type control neurons can compensate the migratory\r\ndeficits of a genetically modified neuronal sub–population in the developing cortex."}],"_id":"12726","alternative_title":["ISTA Thesis"],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Synchronization in collectively moving active matter","has_accepted_license":"1","OA_place":"publisher","degree_awarded":"PhD","status":"public","month":"03","related_material":{"record":[{"id":"461","relation":"part_of_dissertation","status":"public"},{"id":"10791","relation":"part_of_dissertation","status":"public"},{"status":"public","id":"7932","relation":"part_of_dissertation"},{"status":"public","relation":"part_of_dissertation","id":"10703"},{"relation":"new_edition","id":"14530","status":"public"}]},"day":"23","corr_author":"1","doi":"10.15479/at:ista:12726","fulldoi":"https://doi.org/10.15479/at:ista:12726","supervisor":[{"last_name":"Hof","id":"3A374330-F248-11E8-B48F-1D18A9856A87","full_name":"Hof, Björn","orcid":"0000-0003-2057-2754","first_name":"Björn"}],"article_processing_charge":"No","year":"2023","publication_status":"published","date_created":"2023-03-15T13:22:13Z","date_updated":"2026-04-07T13:29:13Z","date_published":"2023-03-23T00:00:00Z","citation":{"short":"M. Riedl, Synchronization in Collectively Moving Active Matter, Institute of Science and Technology Austria, 2023.","ieee":"M. Riedl, “Synchronization in collectively moving active matter,” Institute of Science and Technology Austria, 2023.","ama":"Riedl M. Synchronization in collectively moving active matter. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12726\">10.15479/at:ista:12726</a>","chicago":"Riedl, Michael. “Synchronization in Collectively Moving Active Matter.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12726\">https://doi.org/10.15479/at:ista:12726</a>.","mla":"Riedl, Michael. <i>Synchronization in Collectively Moving Active Matter</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12726\">10.15479/at:ista:12726</a>.","ista":"Riedl M. 2023. Synchronization in collectively moving active matter. Institute of Science and Technology Austria.","apa":"Riedl, M. (2023). <i>Synchronization in collectively moving active matter</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12726\">https://doi.org/10.15479/at:ista:12726</a>"},"file_date_updated":"2023-11-24T11:57:46Z","author":[{"last_name":"Riedl","full_name":"Riedl, Michael","orcid":"0000-0003-4844-6311","id":"3BE60946-F248-11E8-B48F-1D18A9856A87","first_name":"Michael"}],"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"Bio"}],"type":"dissertation","publication_identifier":{"issn":["2663-337X"]},"file":[{"description":"the main file is missing the bibliography. See new thesis record 14530 for updated files.","content_type":"application/pdf","access_level":"closed","date_created":"2023-03-23T12:49:23Z","relation":"main_file","checksum":"eba0e19fe57a8c15e7aeab55a845efb7","file_id":"12745","creator":"cchlebak","file_name":"Thesis_Riedl_2023.pdf","date_updated":"2023-11-24T11:57:46Z","file_size":63734746},{"relation":"source_file","checksum":"0eb7b650cc8ae843bcec7c8a6109ae03","access_level":"closed","content_type":"application/octet-stream","date_created":"2023-03-23T12:54:34Z","date_updated":"2023-09-24T22:30:03Z","file_name":"Thesis_Riedl_2023_source.rar","file_size":339473651,"creator":"cchlebak","file_id":"12746","embargo_to":"open_access"}],"publisher":"Institute of Science and Technology Austria","ddc":["530"],"language":[{"iso":"eng"}],"page":"260"},{"publication_identifier":{"issn":["2663-337X"]},"file":[{"file_size":42167561,"file_name":"Thesis_sub_PBrighi.zip","date_updated":"2023-03-23T16:42:56Z","file_id":"12753","creator":"pbrighi","checksum":"5d2de651ef9449c1b8dc27148ca74777","relation":"source_file","date_created":"2023-03-23T16:42:56Z","content_type":"application/zip","access_level":"closed"},{"creator":"pbrighi","file_id":"12754","success":1,"file_size":13977000,"date_updated":"2023-03-23T16:43:14Z","file_name":"Thesis_PBrighi.pdf","content_type":"application/pdf","date_created":"2023-03-23T16:43:14Z","access_level":"open_access","checksum":"7caa153d4a5b0873a79358787d2dfe1e","relation":"main_file"}],"ddc":["530"],"publisher":"Institute of Science and Technology Austria","page":"158","language":[{"iso":"eng"}],"oa":1,"file_date_updated":"2023-03-23T16:43:14Z","author":[{"first_name":"Pietro","full_name":"Brighi, Pietro","orcid":"0000-0002-7969-2729","id":"4115AF5C-F248-11E8-B48F-1D18A9856A87","last_name":"Brighi"}],"tmp":{"image":"/images/cc_by_nc_sa.png","short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode"},"citation":{"short":"P. Brighi, Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems, Institute of Science and Technology Austria, 2023.","ama":"Brighi P. Ergodicity breaking in disordered and kinetically constrained quantum many-body systems. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12732\">10.15479/at:ista:12732</a>","ieee":"P. Brighi, “Ergodicity breaking in disordered and kinetically constrained quantum many-body systems,” Institute of Science and Technology Austria, 2023.","chicago":"Brighi, Pietro. “Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12732\">https://doi.org/10.15479/at:ista:12732</a>.","apa":"Brighi, P. (2023). <i>Ergodicity breaking in disordered and kinetically constrained quantum many-body systems</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12732\">https://doi.org/10.15479/at:ista:12732</a>","mla":"Brighi, Pietro. <i>Ergodicity Breaking in Disordered and Kinetically Constrained Quantum Many-Body Systems</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12732\">10.15479/at:ista:12732</a>.","ista":"Brighi P. 2023. Ergodicity breaking in disordered and kinetically constrained quantum many-body systems. Institute of Science and Technology Austria."},"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","acknowledged_ssus":[{"_id":"ScienComp"}],"type":"dissertation","article_processing_charge":"No","supervisor":[{"last_name":"Serbyn","first_name":"Maksym","full_name":"Serbyn, Maksym","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"}],"doi":"10.15479/at:ista:12732","fulldoi":"https://doi.org/10.15479/at:ista:12732","date_created":"2023-03-17T13:30:48Z","publication_status":"published","year":"2023","date_updated":"2026-04-07T13:26:32Z","date_published":"2023-03-21T00:00:00Z","oa_version":"Published Version","_id":"12732","ec_funded":1,"abstract":[{"text":"Nonergodic systems, whose out-of-equilibrium dynamics fail to thermalize, provide a fascinating research direction both for fundamental reasons and for application in state of the art quantum devices.\r\nGoing beyond the description of statistical mechanics, ergodicity breaking yields a new paradigm in quantum many-body physics, introducing novel phases of matter with no counterpart at equilibrium.\r\nIn this Thesis, we address different open questions in the field, focusing on disorder-induced many-body localization (MBL) and on weak ergodicity breaking in kinetically constrained models.\r\nIn particular, we contribute to the debate about transport in kinetically constrained models, studying the effect of $U(1)$ conservation and inversion-symmetry breaking in a family of quantum East models.\r\nUsing tensor network techniques, we analyze the dynamics of large MBL systems beyond the limit of exact numerical methods.\r\nIn this setting, we approach the debated topic of the coexistence of localized and thermal eigenstates separated by energy thresholds known as many-body mobility edges.\r\nInspired by recent experiments, our work further investigates the localization of a small bath induced by the coupling to a large localized chain, the so-called MBL proximity effect.\r\n\r\nIn the first Chapter, we introduce a family of particle-conserving kinetically constrained models, inspired by the quantum East model.\r\nThe system we study features strong inversion-symmetry breaking, due to the nature of the correlated hopping.\r\nWe show that these models host so-called quantum Hilbert space fragmentation, consisting of disconnected subsectors in an entangled basis, and further provide an analytical description of this phenomenon.\r\nWe further probe its effect on dynamics of simple product states, showing revivals in fidelity and local observalbes.\r\nThe study of dynamics within the largest subsector reveals an anomalous transient superdiffusive behavior crossing over to slow logarithmic dynamics at later times.\r\nThis work suggests that particle conserving constrained models with inversion-symmetry breaking realize new universality classes of dynamics and invite their further theoretical and experimental studies.\r\n\r\nNext, we use kinetic constraints and disorder to design a model with many-body mobility edges in particle density.\r\nThis feature allows to study the dynamics of localized and thermal states in large systems beyond the limitations of previous studies.\r\nThe time-evolution shows typical signatures of localization at small densities, replaced by thermal behavior at larger densities.\r\nOur results provide evidence in favor of the stability of many-body mobility edges, which was recently challenged by a theoretical argument.\r\nTo support our findings, we probe the mechanism proposed as a cause of delocalization in many-body localized systems with mobility edges suggesting its ineffectiveness in the model studied.\r\n\r\nIn the last Chapter of this Thesis, we address the topic of many-body localization proximity effect.\r\nWe study a model inspired by recent experiments, featuring Anderson localized coupled to a small bath of free hard-core bosons.\r\nThe interaction among the two particle species results in non-trivial dynamics, which we probe using tensor network techniques.\r\nOur simulations show convincing evidence of many-body localization proximity effect when the bath is composed by a single free particle and interactions are strong.\r\nWe furthter observe an anomalous entanglement dynamics, which we explain through a phenomenological theory.\r\nFinally, we extract highly excited eigenstates of large systems, providing supplementary evidence in favor of our findings.","lang":"eng"}],"project":[{"grant_number":"850899","_id":"23841C26-32DE-11EA-91FC-C7463DDC885E","call_identifier":"H2020","name":"Non-Ergodic Quantum Matter: Universality, Dynamics and Control"}],"department":[{"_id":"GradSch"},{"_id":"MaSe"}],"alternative_title":["ISTA Thesis"],"OA_place":"publisher","degree_awarded":"PhD","has_accepted_license":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Ergodicity breaking in disordered and kinetically constrained quantum many-body systems","corr_author":"1","status":"public","day":"21","month":"03","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"12750"},{"status":"public","id":"11470","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","id":"8308","status":"public"},{"id":"11469","relation":"part_of_dissertation","status":"public"}]}},{"main_file_link":[{"url":"https://doi.org/10.1145/3572848.3577512","open_access":"1"}],"type":"conference_poster","author":[{"last_name":"Aksenov","full_name":"Aksenov, Vitaly","first_name":"Vitaly"},{"full_name":"Brown, Trevor A","id":"3569F0A0-F248-11E8-B48F-1D18A9856A87","first_name":"Trevor A","last_name":"Brown"},{"last_name":"Fedorov","id":"2e711909-896a-11ed-bdf8-eb0f5a2984c6","full_name":"Fedorov, Alexander","first_name":"Alexander"},{"first_name":"Ilya","full_name":"Kokorin, Ilya","last_name":"Kokorin"}],"conference":{"end_date":"2023-03-01","location":"Montreal, QB, Canada","start_date":"2023-02-25","name":"PPoPP: Sympopsium on Principles and Practice of Parallel Programming"},"citation":{"ama":"Aksenov V, Brown TA, Fedorov A, Kokorin I. <i>Unexpected Scaling in Path Copying Trees</i>. Association for Computing Machinery; 2023:438-440. doi:<a href=\"https://doi.org/10.1145/3572848.3577512\">10.1145/3572848.3577512</a>","ieee":"V. Aksenov, T. A. Brown, A. Fedorov, and I. Kokorin, <i>Unexpected scaling in path copying trees</i>. Association for Computing Machinery, 2023, pp. 438–440.","short":"V. Aksenov, T.A. Brown, A. Fedorov, I. Kokorin, Unexpected Scaling in Path Copying Trees, Association for Computing Machinery, 2023.","mla":"Aksenov, Vitaly, et al. “Unexpected Scaling in Path Copying Trees.” <i>Proceedings of the ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming</i>, Association for Computing Machinery, 2023, pp. 438–40, doi:<a href=\"https://doi.org/10.1145/3572848.3577512\">10.1145/3572848.3577512</a>.","ista":"Aksenov V, Brown TA, Fedorov A, Kokorin I. 2023. Unexpected scaling in path copying trees, Association for Computing Machinery,p.","apa":"Aksenov, V., Brown, T. A., Fedorov, A., &#38; Kokorin, I. (2023). <i>Unexpected scaling in path copying trees</i>. <i>Proceedings of the ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming</i> (pp. 438–440). Montreal, QB, Canada: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3572848.3577512\">https://doi.org/10.1145/3572848.3577512</a>","chicago":"Aksenov, Vitaly, Trevor A Brown, Alexander Fedorov, and Ilya Kokorin. <i>Unexpected Scaling in Path Copying Trees</i>. <i>Proceedings of the ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming</i>. Association for Computing Machinery, 2023. <a href=\"https://doi.org/10.1145/3572848.3577512\">https://doi.org/10.1145/3572848.3577512</a>."},"ddc":["000"],"publisher":"Association for Computing Machinery","page":"438-440","oa":1,"language":[{"iso":"eng"}],"publication_identifier":{"isbn":["9798400700156"]},"acknowledgement":"This work was supported by: the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Program grant: RGPIN-2019-04227, and the Canada Foundation for Innovation John R. Evans Leaders Fund (CFI-JELF) with equal support from the Ontario Research Fund CFI Leaders Opportunity Fund: 38512.","title":"Unexpected scaling in path copying trees","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","month":"02","day":"25","status":"public","abstract":[{"lang":"eng","text":"Although a wide variety of handcrafted concurrent data structures have been proposed, there is considerable interest in universal approaches (Universal Constructions or UCs) for building concurrent data structures. UCs (semi-)automatically convert a sequential data structure into a concurrent one. The simplest approach uses locks [3, 6] that protect a sequential data structure and allow only one process to access it at a time. However, the resulting data structure is blocking. Most work on UCs instead focuses on obtaining non-blocking progress guarantees such as obstruction-freedom, lock-freedom or wait-freedom. Many non-blocking UCs have appeared. Key examples include the seminal wait-free UC [2] by Herlihy, a NUMA-aware UC [10] by Yi et al., and an efficient UC for large objects [1] by Fatourou et al."}],"_id":"12736","oa_version":"Published Version","department":[{"_id":"DaAl"},{"_id":"GradSch"}],"quality_controlled":"1","date_updated":"2026-06-18T17:29:03Z","date_published":"2023-02-25T00:00:00Z","publication":"Proceedings of the ACM SIGPLAN Symposium on Principles and Practice of Parallel Programming","article_processing_charge":"No","scopus_import":"1","fulldoi":"https://doi.org/10.1145/3572848.3577512","doi":"10.1145/3572848.3577512","publication_status":"published","date_created":"2023-03-19T23:00:58Z","year":"2023"},{"alternative_title":["ISTA Thesis"],"_id":"12826","ec_funded":1,"abstract":[{"lang":"eng","text":"During navigation, animals can infer the structure of the environment by computing the optic flow cues elicited by their own movements, and subsequently use this information to instruct proper locomotor actions. These computations require a panoramic assessment of the visual environment in order to disambiguate similar sensory experiences that may require distinct behavioral responses. The estimation of the global motion patterns is therefore essential for successful navigation. Yet, our understanding of the algorithms and implementations that enable coherent panoramic visual perception remains scarce. Here I pursue this problem by dissecting the functional aspects of interneuronal communication in the lobula plate tangential cell network in Drosophila melanogaster. The results presented in the thesis demonstrate that the basis for effective interpretation of the optic flow in this circuit are stereotyped synaptic connections that mediate the formation of distinct subnetworks, each extracting a particular pattern of global motion. \r\nFirstly, I show that gap junctions are essential for a correct interpretation of binocular motion cues by horizontal motion-sensitive cells. HS cells form electrical synapses with contralateral H2 neurons that are involved in detecting yaw rotation and translation. I developed an FlpStop-mediated mutant of a gap junction protein ShakB that disrupts these electrical synapses. While the loss of electrical synapses does not affect the tuning of the direction selectivity in HS neurons, it severely alters their sensitivity to horizontal motion in the contralateral side. These physiological changes result in an inappropriate integration of binocular motion cues in walking animals. While wild-type flies form a binocular perception of visual motion by non-linear integration of monocular optic flow cues, the mutant flies sum the monocular inputs linearly. These results indicate that rather than averaging signals in neighboring neurons, gap-junctions operate in conjunction with chemical synapses to mediate complex non-linear optic flow computations.\r\nSecondly, I show that stochastic manipulation of neuronal activity in the lobula plate tangential cell network is a powerful approach to study the neuronal implementation of optic flow-based navigation in flies. Tangential neurons form multiple subnetworks, each mediating course-stabilizing response to a particular global pattern of visual motion. Application of genetic mosaic techniques can provide sparse optogenetic activation of HS cells in numerous combinations. These distinct combinations of activated neurons drive an array of distinct behavioral responses, providing important insights into how visuomotor transformation is performed in the lobula plate tangential cell network. This approach can be complemented by stochastic silencing of tangential neurons, enabling direct assessment of the functional role of individual tangential neurons in the processing of specific visual motion patterns.\r\n\tTaken together, the findings presented in this thesis suggest that establishing specific activity patterns of tangential cells via stereotyped synaptic connectivity is a key to efficient optic flow-based navigation in Drosophila melanogaster."}],"oa_version":"Published Version","department":[{"_id":"MaJö"},{"_id":"GradSch"}],"project":[{"name":"International IST Doctoral Program","call_identifier":"H2020","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","grant_number":"665385"}],"corr_author":"1","day":"18","month":"04","status":"public","has_accepted_license":"1","OA_place":"publisher","degree_awarded":"PhD","title":"Neural control of optic flow-based navigation in Drosophila melanogaster","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","date_created":"2023-04-14T14:56:04Z","publication_status":"published","year":"2023","supervisor":[{"last_name":"Jösch","full_name":"Jösch, Maximilian A","orcid":"0000-0002-3937-1330","id":"2BD278E6-F248-11E8-B48F-1D18A9856A87","first_name":"Maximilian A"}],"article_processing_charge":"No","fulldoi":"https://doi.org/10.15479/at:ista:12826","doi":"10.15479/at:ista:12826","date_published":"2023-04-18T00:00:00Z","date_updated":"2026-04-07T13:26:49Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"}],"author":[{"last_name":"Pokusaeva","id":"3184041C-F248-11E8-B48F-1D18A9856A87","full_name":"Pokusaeva, Victoria","orcid":"0000-0001-7660-444X","first_name":"Victoria"}],"file_date_updated":"2023-04-20T09:26:51Z","citation":{"short":"V. Pokusaeva, Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster, Institute of Science and Technology Austria, 2023.","ieee":"V. Pokusaeva, “Neural control of optic flow-based navigation in Drosophila melanogaster,” Institute of Science and Technology Austria, 2023.","ama":"Pokusaeva V. Neural control of optic flow-based navigation in Drosophila melanogaster. 2023. doi:<a href=\"https://doi.org/10.15479/at:ista:12826\">10.15479/at:ista:12826</a>","chicago":"Pokusaeva, Victoria. “Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/at:ista:12826\">https://doi.org/10.15479/at:ista:12826</a>.","apa":"Pokusaeva, V. (2023). <i>Neural control of optic flow-based navigation in Drosophila melanogaster</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:12826\">https://doi.org/10.15479/at:ista:12826</a>","ista":"Pokusaeva V. 2023. Neural control of optic flow-based navigation in Drosophila melanogaster. Institute of Science and Technology Austria.","mla":"Pokusaeva, Victoria. <i>Neural Control of Optic Flow-Based Navigation in Drosophila Melanogaster</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/at:ista:12826\">10.15479/at:ista:12826</a>."},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"type":"dissertation","file":[{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","access_level":"closed","date_created":"2023-04-20T09:14:38Z","relation":"source_file","checksum":"5f589a9af025f7eeebfd0c186209913e","file_id":"12857","creator":"vpokusae","date_updated":"2023-04-20T09:26:51Z","file_name":"Thesis_Pokusaeva.docx","file_size":14507243},{"file_name":"Thesis_Pokusaeva.pdf","date_updated":"2023-04-20T09:14:44Z","file_size":10090711,"success":1,"file_id":"12858","creator":"vpokusae","relation":"main_file","checksum":"bbeed76db45a996b4c91a9abe12ce0ec","content_type":"application/pdf","date_created":"2023-04-20T09:14:44Z","access_level":"open_access"}],"publication_identifier":{"issn":["2663-337X"]},"page":"106","language":[{"iso":"eng"}],"oa":1,"ddc":["570","571"],"publisher":"Institute of Science and Technology Austria"},{"status":"public","related_material":{"record":[{"relation":"used_in_publication","id":"14505","status":"deleted"},{"relation":"used_in_publication","id":"12890","status":"public"}]},"day":"26","month":"04","corr_author":"1","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"research_data","title":"Research data for: A stochastic cellular automaton model of culture formation","has_accepted_license":"1","license":"https://creativecommons.org/publicdomain/zero/1.0/","department":[{"_id":"GradSch"},{"_id":"RoSe"}],"citation":{"apa":"Klausen, F. R., &#38; Lauritsen, A. B. (2023). Research data for: A stochastic cellular automaton model of culture formation. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:12869\">https://doi.org/10.15479/AT:ISTA:12869</a>","ista":"Klausen FR, Lauritsen AB. 2023. Research data for: A stochastic cellular automaton model of culture formation, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:12869\">10.15479/AT:ISTA:12869</a>.","mla":"Klausen, Frederik Ravn, and Asbjørn Bækgaard Lauritsen. <i>Research Data for: A Stochastic Cellular Automaton Model of Culture Formation</i>. Institute of Science and Technology Austria, 2023, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12869\">10.15479/AT:ISTA:12869</a>.","chicago":"Klausen, Frederik Ravn, and Asbjørn Bækgaard Lauritsen. “Research Data for: A Stochastic Cellular Automaton Model of Culture Formation.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/AT:ISTA:12869\">https://doi.org/10.15479/AT:ISTA:12869</a>.","ama":"Klausen FR, Lauritsen AB. Research data for: A stochastic cellular automaton model of culture formation. 2023. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12869\">10.15479/AT:ISTA:12869</a>","ieee":"F. R. Klausen and A. B. Lauritsen, “Research data for: A stochastic cellular automaton model of culture formation.” Institute of Science and Technology Austria, 2023.","short":"F.R. Klausen, A.B. Lauritsen, (2023)."},"tmp":{"name":"Creative Commons Public Domain Dedication (CC0 1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","image":"/images/cc_0.png","short":"CC0 (1.0)"},"oa_version":"Published Version","file_date_updated":"2023-04-26T12:30:06Z","_id":"12869","abstract":[{"text":"We introduce a stochastic cellular automaton as a model for culture and border formation. The model can be conceptualized as a game where the expansion rate of cultures is quantified in terms of their area and perimeter in such a way that approximately round cultures get a competitive advantage.  We first analyse the model  with periodic boundary conditions, where we study how the model can end up in a fixed state, i.e. freezes. Then we implement the model on the European geography with mountains and rivers. We see how the model reproduces some qualitative features of European culture formation, namely that rivers and mountains are more frequently borders between cultures, mountainous regions tend to have higher cultural diversity and the central European plain has less clear cultural borders. ","lang":"eng"}],"author":[{"last_name":"Klausen","first_name":"Frederik Ravn","full_name":"Klausen, Frederik Ravn"},{"last_name":"Lauritsen","first_name":"Asbjørn Bækgaard","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","orcid":"0000-0003-4476-2288","full_name":"Lauritsen, Asbjørn Bækgaard"}],"oa":1,"date_published":"2023-04-26T00:00:00Z","publisher":"Institute of Science and Technology Austria","ddc":["000"],"date_updated":"2025-09-09T12:26:01Z","acknowledgement":"FRK acknowledges support from the Villum Foundation for support through the QMATH center of Excellence (Grant No. 10059) and the Villum Young Investigator (Grant No. 25452) programs. ","year":"2023","date_created":"2023-04-26T12:34:49Z","file":[{"file_name":"README.md","date_updated":"2023-04-26T12:30:06Z","file_size":4567,"success":1,"file_id":"12870","creator":"alaurits","relation":"main_file","checksum":"85ede12d38bb8d944022a8cba4d719f5","access_level":"open_access","date_created":"2023-04-26T12:30:06Z","content_type":"application/octet-stream"},{"success":1,"file_id":"12871","creator":"alaurits","date_updated":"2023-04-26T12:27:34Z","file_name":"simulations_era=10_flux_varied_europe.zip","file_size":732586731,"date_created":"2023-04-26T12:27:34Z","content_type":"application/x-zip-compressed","access_level":"open_access","relation":"main_file","checksum":"25bf79452ae895f9c8a20571a096b4c3"},{"file_size":1743893150,"date_updated":"2023-04-26T12:29:53Z","file_name":"simulations_era=10_flux_varied_torus.zip","creator":"alaurits","file_id":"12872","success":1,"checksum":"bca48d80ece73eb169aee7211a4a751a","relation":"main_file","access_level":"open_access","date_created":"2023-04-26T12:29:53Z","content_type":"application/x-zip-compressed"},{"file_name":"simulations_era=10_R_varied_torus.zip","date_updated":"2023-04-26T12:29:19Z","file_size":878391851,"success":1,"file_id":"12873","creator":"alaurits","relation":"main_file","checksum":"e77a655db15486a387a36362fbf0b665","access_level":"open_access","date_created":"2023-04-26T12:29:19Z","content_type":"application/x-zip-compressed"},{"file_size":201652478,"date_updated":"2023-04-26T12:30:05Z","file_name":"simulations_era=100.zip","creator":"alaurits","file_id":"12874","success":1,"checksum":"8556406513adc4aa2e0417f46680f627","relation":"main_file","access_level":"open_access","content_type":"application/x-zip-compressed","date_created":"2023-04-26T12:30:05Z"}],"doi":"10.15479/AT:ISTA:12869","fulldoi":"https://doi.org/10.15479/AT:ISTA:12869","article_processing_charge":"No"},{"status":"public","isi":1,"day":"08","month":"11","related_material":{"link":[{"url":"https://github.com/FrederikRavnKlausen/model-for-culture-formation","relation":"software"}],"record":[{"status":"public","id":"12869","relation":"research_data"}]},"corr_author":"1","user_id":"317138e5-6ab7-11ef-aa6d-ffef3953e345","title":"Stochastic cellular automaton model of culture formation","external_id":{"arxiv":["2305.02153"],"isi":["001106396300005"],"pmid":["38115445"]},"department":[{"_id":"GradSch"},{"_id":"RoSe"}],"oa_version":"Preprint","abstract":[{"text":"We introduce a stochastic cellular automaton as a model for culture and border formation. The model can be conceptualized as a game where the expansion rate of cultures is quantified in terms of their area and perimeter in such a way that approximately geometrically round cultures get a competitive advantage. We first analyze the model with periodic boundary conditions, where we study how the model can end up in a fixed state, i.e., freezes. Then we implement the model on the European geography with mountains and rivers. We see how the model reproduces some qualitative features of European culture formation, namely, that rivers and mountains are more frequently borders between cultures, mountainous regions tend to have higher cultural diversity, and the central European plain has less clear cultural borders.","lang":"eng"}],"_id":"12890","pmid":1,"publication":"Physical Review E","date_published":"2023-11-08T00:00:00Z","intvolume":"       108","quality_controlled":"1","date_updated":"2025-09-09T12:26:01Z","year":"2023","article_type":"original","publication_status":"published","date_created":"2023-05-04T08:35:01Z","doi":"10.1103/PhysRevE.108.054307","fulldoi":"https://doi.org/10.1103/PhysRevE.108.054307","scopus_import":"1","article_processing_charge":"No","type":"journal_article","issue":"5","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2305.02153"}],"article_number":"054307","citation":{"ieee":"F. R. Klausen and A. B. Lauritsen, “Stochastic cellular automaton model of culture formation,” <i>Physical Review E</i>, vol. 108, no. 5. American Physical Society, 2023.","ama":"Klausen FR, Lauritsen AB. Stochastic cellular automaton model of culture formation. <i>Physical Review E</i>. 2023;108(5). doi:<a href=\"https://doi.org/10.1103/PhysRevE.108.054307\">10.1103/PhysRevE.108.054307</a>","short":"F.R. Klausen, A.B. Lauritsen, Physical Review E 108 (2023).","apa":"Klausen, F. R., &#38; Lauritsen, A. B. (2023). Stochastic cellular automaton model of culture formation. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevE.108.054307\">https://doi.org/10.1103/PhysRevE.108.054307</a>","mla":"Klausen, Frederik Ravn, and Asbjørn Bækgaard Lauritsen. “Stochastic Cellular Automaton Model of Culture Formation.” <i>Physical Review E</i>, vol. 108, no. 5, 054307, American Physical Society, 2023, doi:<a href=\"https://doi.org/10.1103/PhysRevE.108.054307\">10.1103/PhysRevE.108.054307</a>.","ista":"Klausen FR, Lauritsen AB. 2023. Stochastic cellular automaton model of culture formation. Physical Review E. 108(5), 054307.","chicago":"Klausen, Frederik Ravn, and Asbjørn Bækgaard Lauritsen. “Stochastic Cellular Automaton Model of Culture Formation.” <i>Physical Review E</i>. American Physical Society, 2023. <a href=\"https://doi.org/10.1103/PhysRevE.108.054307\">https://doi.org/10.1103/PhysRevE.108.054307</a>."},"author":[{"full_name":"Klausen, Frederik Ravn","first_name":"Frederik Ravn","last_name":"Klausen"},{"first_name":"Asbjørn Bækgaard","orcid":"0000-0003-4476-2288","full_name":"Lauritsen, Asbjørn Bækgaard","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","last_name":"Lauritsen"}],"oa":1,"language":[{"iso":"eng"}],"arxiv":1,"publisher":"American Physical Society","acknowledgement":"Thanks to Kim Sneppen, Svend Krøjer, Peter Wildemann, Peter Rasmussen and Kent Bækgaard Lauritsen for discussions and suggestions. FRK acknowledges support from the Villum Foundation for support through the QMATH center of Excellence (Grant No. 10059) and the Villum Young Investigator (Grant No. 25452) programs.","publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"volume":108},{"status":"public","month":"05","day":"05","related_material":{"record":[{"status":"public","id":"13175","relation":"new_edition"},{"relation":"part_of_dissertation","id":"10924","status":"public"},{"status":"public","id":"9114","relation":"part_of_dissertation"}]},"keyword":["quantum optics","electrooptics","quantum networks","quantum communication","transduction"],"corr_author":"1","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","title":"Cavity quantum electrooptics","has_accepted_license":"1","degree_awarded":"PhD","OA_place":"publisher","alternative_title":["ISTA Thesis"],"project":[{"grant_number":"758053","_id":"26336814-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"A Fiber Optic Transceiver for Superconducting Qubits"},{"grant_number":"899354","_id":"9B868D20-BA93-11EA-9121-9846C619BF3A","call_identifier":"H2020","name":"Quantum Local Area Networks with Superconducting Qubits"},{"_id":"bdb108fd-d553-11ed-ba76-83dc74a9864f","grant_number":"F07105","name":"QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration of Superconducting Quantum Circuits"}],"department":[{"_id":"GradSch"},{"_id":"JoFi"}],"oa_version":"Published Version","_id":"12900","ec_funded":1,"abstract":[{"lang":"eng","text":"About a 100 years ago, we discovered that our universe is inherently noisy, that is, measuring any physical quantity with a precision beyond a certain point is not possible because of an omnipresent inherent noise. We call this - the quantum noise. Certain physical processes allow this quantum noise to get correlated in conjugate physical variables. These quantum correlations can be used to go beyond the potential of our inherently noisy universe and obtain a quantum advantage over the classical applications. \r\n\r\nQuantum noise being inherent also means that, at the fundamental level, the physical quantities are not well defined and therefore, objects can stay in multiple states at the same time. For example, the position of a particle not being well defined means that the particle is in multiple positions at the same time. About 4 decades ago, we started exploring the possibility of using objects which can be in multiple states at the same time to increase the dimensionality in computation. Thus, the field of quantum computing was born. We discovered that using quantum entanglement, a property closely related to quantum correlations, can be used to speed up computation of certain problems, such as factorisation of large numbers, faster than any known classical algorithm. Thus began the pursuit to make quantum computers a reality. \r\n\r\nTill date, we have explored quantum control over many physical systems including photons, spins, atoms, ions and even simple circuits made up of superconducting material. However, there persists one ubiquitous theme. The more readily a system interacts with an external field or matter, the more easily we can control it. But this also means that such a system can easily interact with a noisy environment and quickly lose its coherence. Consequently, such systems like electron spins need to be protected from the environment to ensure the longevity of their coherence. Other systems like nuclear spins are naturally protected as they do not interact easily with the environment. But, due to the same reason, it is harder to interact with such systems. \r\n\r\nAfter decades of experimentation with various systems, we are convinced that no one type of quantum system would be the best for all the quantum applications. We would need hybrid systems which are all interconnected - much like the current internet where all sorts of devices can all talk to each other - but now for quantum devices. A quantum internet. \r\n\r\nOptical photons are the best contenders to carry information for the quantum internet. They can carry quantum information cheaply and without much loss - the same reasons which has made them the backbone of our current internet. Following this direction, many systems, like trapped ions, have already demonstrated successful quantum links over a large distances using optical photons. However, some of the most promising contenders for quantum computing which are based on microwave frequencies have been left behind. This is because high energy optical photons can adversely affect fragile low-energy microwave systems. \r\n\r\nIn this thesis, we present substantial progress on this missing quantum link between microwave and optics using electrooptical nonlinearities in lithium niobate. The nonlinearities are enhanced by using resonant cavities for all the involved modes leading to observation of strong direct coupling between optical and microwave frequencies. With this strong coupling we are not only able to achieve almost 100\\% internal conversion efficiency with low added noise, thus presenting a quantum-enabled transducer, but also we are able to observe novel effects such as cooling of a microwave mode using optics. The strong coupling regime also leads to direct observation of dynamical backaction effect between microwave and optical frequencies which are studied in detail here. Finally, we also report first observation of microwave-optics entanglement in form of two-mode squeezed vacuum squeezed 0.7dB below vacuum level. \r\nWith this new bridge between microwave and optics, the microwave-based quantum technologies can finally be a part of a quantum network which is based on optical photons - putting us one step closer to a future with quantum internet. 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Institute of Science and Technology Austria."},"file_date_updated":"2023-07-06T11:37:40Z","author":[{"last_name":"Sahu","full_name":"Sahu, Rishabh","orcid":"0000-0001-6264-2162","id":"47D26E34-F248-11E8-B48F-1D18A9856A87","first_name":"Rishabh"}],"language":[{"iso":"eng"}],"page":"190","publisher":"Institute of Science and Technology Austria","ddc":["537","535","539"],"file":[{"date_created":"2023-05-09T08:45:14Z","access_level":"closed","content_type":"application/x-zip-compressed","relation":"source_file","checksum":"8cbdab9c37ee55e591092a6f66b272c4","embargo_to":"open_access","creator":"rsahu","file_id":"12928","file_name":"thesis.zip","date_updated":"2023-06-06T22:30:03Z","file_size":36767177},{"file_size":17501990,"date_updated":"2023-07-06T11:37:40Z","file_name":"thesis_pdfa_final.pdf","file_id":"12929","creator":"rsahu","checksum":"439659ead46618147309be39d9dd5a8c","relation":"main_file","access_level":"closed","content_type":"application/pdf","date_created":"2023-05-09T08:51:17Z"}],"publication_identifier":{"issn":["2663-337X"],"isbn":["978-3-99078-030-5"]}},{"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","short":"CC BY (4.0)"},"citation":{"short":"G. Puixeu Sala, (2023).","ieee":"G. Puixeu Sala, “Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster.” Institute of Science and Technology Austria, 2023.","ama":"Puixeu Sala G. Data from: Sex-specific estimation of cis and trans regulation of gene expression in heads and gonads of Drosophila melanogaster. 2023. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:12933\">10.15479/AT:ISTA:12933</a>","chicago":"Puixeu Sala, Gemma. “Data from: Sex-Specific Estimation of Cis and Trans Regulation of Gene Expression in Heads and Gonads of Drosophila Melanogaster.” Institute of Science and Technology Austria, 2023. <a href=\"https://doi.org/10.15479/AT:ISTA:12933\">https://doi.org/10.15479/AT:ISTA:12933</a>.","ista":"Puixeu Sala G. 2023. 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