[{"article_number":"L053502","_id":"21982","intvolume":"       113","date_published":"2026-05-14T00:00:00Z","acknowledgement":"This research was supported by the Scientific Service Units of The Institute of Science and Technology Austria (ISTA) through resources provided by the Miba Machine Shop and the Scientific Computing Facility. J.B. acknowledges funding from the European Union's Horizon research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No. 101106500.","language":[{"iso":"eng"}],"scopus_import":"1","OA_place":"publisher","issue":"5","date_created":"2026-06-10T07:36:41Z","publisher":"American Physical Society","article_type":"letter_note","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","abstract":[{"lang":"eng","text":"A floating Leidenfrost droplet exhibits curvature inversion of its underside, due to the balance of vapor pressure and surface tension. Using interferometric imaging, we find different behavior for a levitated hydrogel sphere. Curvature inversion is observed briefly just after deposition, but quickly gives way to a steady state with no inversion. We show the essential role of vaporization in shaping the underbelly of the hydrogel, where changes due to direct mass loss are more significant than the balance of vapor pressure and elastic forces."}],"quality_controlled":"1","author":[{"full_name":"Diaz Melian, Vicente L","id":"b6798902-eea0-11ea-9cbc-a8e14286c631","first_name":"Vicente L","last_name":"Diaz Melian"},{"orcid":"0000-0002-5010-6984","first_name":"Isaac C","id":"a550210f-223c-11ec-8182-e2d45e817efb","last_name":"Lenton","full_name":"Lenton, Isaac C"},{"full_name":"Binysh, Jack","first_name":"Jack","last_name":"Binysh"},{"full_name":"Souslov, Anton","last_name":"Souslov","first_name":"Anton"},{"last_name":"Waitukaitis","id":"3A1FFC16-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2299-3176","first_name":"Scott R","full_name":"Waitukaitis, Scott R"}],"department":[{"_id":"ScWa"},{"_id":"GradSch"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Geometry of the vapor layer under a Leidenfrost hydrogel sphere","publication_identifier":{"issn":["2470-0045"],"eissn":["2470-0053"]},"arxiv":1,"corr_author":"1","type":"journal_article","publication":"Physical Review E","month":"05","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"ScienComp"}],"has_accepted_license":"1","external_id":{"arxiv":["2507.04982"]},"citation":{"ieee":"V. L. Diaz Melian, I. C. Lenton, J. Binysh, A. Souslov, and S. R. Waitukaitis, “Geometry of the vapor layer under a Leidenfrost hydrogel sphere,” <i>Physical Review E</i>, vol. 113, no. 5. American Physical Society, 2026.","chicago":"Diaz Melian, Vicente L, Isaac C Lenton, Jack Binysh, Anton Souslov, and Scott R Waitukaitis. “Geometry of the Vapor Layer under a Leidenfrost Hydrogel Sphere.” <i>Physical Review E</i>. American Physical Society, 2026. <a href=\"https://doi.org/10.1103/m7gr-2t6j\">https://doi.org/10.1103/m7gr-2t6j</a>.","ista":"Diaz Melian VL, Lenton IC, Binysh J, Souslov A, Waitukaitis SR. 2026. Geometry of the vapor layer under a Leidenfrost hydrogel sphere. Physical Review E. 113(5), L053502.","short":"V.L. Diaz Melian, I.C. Lenton, J. Binysh, A. Souslov, S.R. Waitukaitis, Physical Review E 113 (2026).","mla":"Diaz Melian, Vicente L., et al. “Geometry of the Vapor Layer under a Leidenfrost Hydrogel Sphere.” <i>Physical Review E</i>, vol. 113, no. 5, L053502, American Physical Society, 2026, doi:<a href=\"https://doi.org/10.1103/m7gr-2t6j\">10.1103/m7gr-2t6j</a>.","apa":"Diaz Melian, V. L., Lenton, I. C., Binysh, J., Souslov, A., &#38; Waitukaitis, S. R. (2026). Geometry of the vapor layer under a Leidenfrost hydrogel sphere. <i>Physical Review E</i>. American Physical Society. <a href=\"https://doi.org/10.1103/m7gr-2t6j\">https://doi.org/10.1103/m7gr-2t6j</a>","ama":"Diaz Melian VL, Lenton IC, Binysh J, Souslov A, Waitukaitis SR. Geometry of the vapor layer under a Leidenfrost hydrogel sphere. <i>Physical Review E</i>. 2026;113(5). doi:<a href=\"https://doi.org/10.1103/m7gr-2t6j\">10.1103/m7gr-2t6j</a>"},"year":"2026","file":[{"checksum":"902cc8d177c8d3ae9cfe07c30375c9a9","access_level":"open_access","relation":"main_file","date_created":"2026-06-16T11:21:53Z","success":1,"file_id":"22014","file_name":"2026_PhysicalReviewE_DiazMelian.pdf","content_type":"application/pdf","creator":"dernst","date_updated":"2026-06-16T11:21:53Z","file_size":3173197}],"file_date_updated":"2026-06-16T11:21:53Z","day":"14","article_processing_charge":"Yes (via OA deal)","volume":113,"oa_version":"Published Version","OA_type":"hybrid","oa":1,"doi":"10.1103/m7gr-2t6j","publication_status":"published","status":"public","PlanS_conform":"1","ddc":["530"],"date_updated":"2026-06-16T11:24:18Z"},{"publication":"Current Opinion in Genetics & Development","month":"05","has_accepted_license":"1","year":"2026","citation":{"ama":"Mascolo E, Körei RE, Herrera-Álvarez S, Guet CC, Crocker J, Tkačik G. Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. <i>Current Opinion in Genetics &#38; Development</i>. 2026;99. doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102483\">10.1016/j.gde.2026.102483</a>","apa":"Mascolo, E., Körei, R. E., Herrera-Álvarez, S., Guet, C. C., Crocker, J., &#38; Tkačik, G. (2026). Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. <i>Current Opinion in Genetics &#38; Development</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.gde.2026.102483\">https://doi.org/10.1016/j.gde.2026.102483</a>","mla":"Mascolo, Elia, et al. “Long-Term Evolution of Regulatory DNA Sequences. Part 1: Simulations on Global, Biophysically-Realistic Genotype–Phenotype Maps.” <i>Current Opinion in Genetics &#38; Development</i>, vol. 99, 102483, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.gde.2026.102483\">10.1016/j.gde.2026.102483</a>.","ista":"Mascolo E, Körei RE, Herrera-Álvarez S, Guet CC, Crocker J, Tkačik G. 2026. Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps. Current Opinion in Genetics &#38; Development. 99, 102483.","short":"E. Mascolo, R.E. Körei, S. Herrera-Álvarez, C.C. Guet, J. Crocker, G. Tkačik, Current Opinion in Genetics &#38; Development 99 (2026).","chicago":"Mascolo, Elia, Reka E Körei, Santiago Herrera-Álvarez, Calin C Guet, Justin Crocker, and Gašper Tkačik. “Long-Term Evolution of Regulatory DNA Sequences. Part 1: Simulations on Global, Biophysically-Realistic Genotype–Phenotype Maps.” <i>Current Opinion in Genetics &#38; Development</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.gde.2026.102483\">https://doi.org/10.1016/j.gde.2026.102483</a>.","ieee":"E. Mascolo, R. E. Körei, S. Herrera-Álvarez, C. C. Guet, J. Crocker, and G. Tkačik, “Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps,” <i>Current Opinion in Genetics &#38; Development</i>, vol. 99. Elsevier, 2026."},"external_id":{"arxiv":["2601.19681"]},"volume":99,"article_processing_charge":"Yes (via OA deal)","day":"09","oa":1,"OA_type":"hybrid","oa_version":"Published Version","ddc":["570"],"PlanS_conform":"1","status":"public","publication_status":"published","doi":"10.1016/j.gde.2026.102483","date_updated":"2026-06-16T12:37:02Z","date_published":"2026-05-09T00:00:00Z","intvolume":"        99","_id":"21983","article_number":"102483","date_created":"2026-06-10T07:37:12Z","OA_place":"publisher","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"We thank Nick Barton and Noa Ottilie Borst for essential contributions to this manuscript.\r\nE.M. acknowledges support from the APART-USA fellowship, jointly funded by the Austrian Academy of Sciences (ÖAW) and the Institute of Science and Technology Austria (ISTA).\r\nThis study was supported by the European Molecular Biology Laboratory (J.C.); the European Molecular Biology Laboratory Interdisciplinary Postdoc Programme (EIPOD) under the Marie Skłodowska-Curie Actions cofund (S.H.A.).","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_type":"original","publisher":"Elsevier","quality_controlled":"1","abstract":[{"lang":"eng","text":"Promoters and enhancers are cis-regulatory elements (CREs), DNA sequences that bind transcription factor (TF) proteins to up- or down-regulate target genes. Decades-long efforts yielded TF-DNA interaction models that predict how strongly an individual TF binds arbitrary DNA sequences and how individual binding events on the CRE combine to affect gene expression. These insights can be synthesized into a global, biophysically realistic, and quantitative genotype–phenotype map for gene regulation, a ‘holy grail’ for the application of evolutionary theory. A global map provides a rare opportunity to simulate the long-term evolution of regulatory sequences and pose several fundamental questions: How long does it take to evolve CREs de novo? How many non-trivial regulatory functions exist in sequence space? How connected are they? For which regulatory architecture is CRE evolution most rapid and evolvable? In this article, the first of a two-part series, we briefly review the pertinent modeling and simulation efforts for a unique system that enables close, quantitative, and mechanistic links between biophysics, as well as systems, synthetic, and evolutionary biology."}],"department":[{"_id":"GradSch"},{"_id":"CaGu"},{"_id":"GaTk"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"author":[{"last_name":"Mascolo","id":"776a6ed0-a053-11f0-8635-80b95e0e0d53","orcid":"0000-0003-2977-7844","first_name":"Elia","full_name":"Mascolo, Elia"},{"last_name":"Körei","id":"50FDE43E-AA30-11E9-A72B-8A12E6697425","first_name":"Reka E","full_name":"Körei, Reka E"},{"first_name":"Santiago","last_name":"Herrera-Álvarez","full_name":"Herrera-Álvarez, Santiago"},{"last_name":"Guet","first_name":"Calin C","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","full_name":"Guet, Calin C"},{"first_name":"Justin","last_name":"Crocker","full_name":"Crocker, Justin"},{"id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6699-1455","first_name":"Gašper","last_name":"Tkačik","full_name":"Tkačik, Gašper"}],"title":"Long-term evolution of regulatory DNA sequences. Part 1: Simulations on global, biophysically-realistic genotype–phenotype maps","main_file_link":[{"url":"https://doi.org/10.1016/j.gde.2026.102483","open_access":"1"}],"corr_author":"1","type":"journal_article","arxiv":1,"publication_identifier":{"eissn":["1879-0380"],"issn":["0959-437X"]}},{"has_accepted_license":"1","year":"2026","citation":{"apa":"Ge, Z., Koczka, L., Mazur, E., Molnar, G., Vladimirtsev, D., Kassem, N., … Friml, J. (n.d.). MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. <i>bioRxiv</i>. <a href=\"https://doi.org/10.1101/2025.10.07.680881\">https://doi.org/10.1101/2025.10.07.680881</a>","ama":"Ge Z, Koczka L, Mazur E, et al. MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>","ista":"Ge Z, Koczka L, Mazur E, Molnar G, Vladimirtsev D, Kassem N, Ait Ikene S, Fiedler L, Friml J. MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis. bioRxiv, <a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>.","mla":"Ge, Zengxiang, et al. “MAKR6 Integrates TMK and CAMEL/CANAR Signalling for Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>, doi:<a href=\"https://doi.org/10.1101/2025.10.07.680881\">10.1101/2025.10.07.680881</a>.","short":"Z. Ge, L. Koczka, E. Mazur, G. Molnar, D. Vladimirtsev, N. Kassem, S. Ait Ikene, L. Fiedler, J. Friml, BioRxiv (n.d.).","chicago":"Ge, Zengxiang, Lilla Koczka, Ewa Mazur, Gergely Molnar, Dmitrii Vladimirtsev, Nada Kassem, Sara Ait Ikene, Lukas Fiedler, and Jiří Friml. “MAKR6 Integrates TMK and CAMEL/CANAR Signalling for Auxin Canalization in Arabidopsis.” <i>BioRxiv</i>, n.d. <a href=\"https://doi.org/10.1101/2025.10.07.680881\">https://doi.org/10.1101/2025.10.07.680881</a>.","ieee":"Z. Ge <i>et al.</i>, “MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis,” <i>bioRxiv</i>. ."},"publication":"bioRxiv","month":"05","ddc":["580"],"doi":"10.1101/2025.10.07.680881","status":"public","publication_status":"submitted","date_updated":"2026-06-19T07:14:01Z","day":"30","article_processing_charge":"No","project":[{"grant_number":"101142681","name":"Cyclic nucleotides as second messengers in plants","_id":"8f347782-16d5-11f0-9cad-8c19706ee739"},{"grant_number":"I06123","name":"Peptide receptors for auxin canalization in Arabidopsis","_id":"bd76d395-d553-11ed-ba76-f678c14f9033"},{"grant_number":"P37051","name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors","_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6"}],"oa":1,"oa_version":"Preprint","OA_type":"green","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2026-05-30T00:00:00Z","_id":"21994","scopus_import":"1","OA_place":"repository","date_created":"2026-06-13T16:57:07Z","acknowledgement":"We would like to thank Dr. Yvon Jaillais (ENS, Lyon) for sharing MAKR2 materials. This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by the Imaging & Optics Facility (IOF) and the Lab Support Facility (LSF). The research in the Friml group leading to these results was funded by the European Research Council (ERC): 101142681 CYNIPS; and the Austrian Science Fund (FWF): I 6123-B and P 37051-B. Ewa Mazur was supported by the National Science Centre (NCN), Poland, under the OPUS call in the WEAVE programme: 2021/43/I/NZ1/01835.","language":[{"iso":"eng"}],"title":"MAKR6 integrates TMK and CAMEL/CANAR signalling for auxin canalization in Arabidopsis","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2025.10.07.680881"}],"type":"preprint","corr_author":"1","abstract":[{"text":"Adaptive plant development is orchestrated, among others, by directional, intercellular transport of the phytohormone auxin. Self-organizing development, such as flexible vasculature formation, depends on so-called auxin canalization, manifested by the gradual formation of auxin transport channels through feedback between auxin signalling and transport. Herein, we identify MAKR6 as an important, novel component in this feedback. MAKR6 expression accumulates strongly in vascular cells and is tightly regulated by auxin via the Aux/IAA-ARF-WRKY23 transcriptional network. MAKR6 is required for auxin canalization-dependent processes, including leaf venation, vasculature regeneration, and de novo auxin channel formation from local auxin sources. Mechanistically, MAKR6 interacts with the PIN1 auxin transporter, modulating its trafficking and polarization. MAKR6 also associates with and integrates two key receptor-like kinase complexes involved in canalization, TMK1/4 and the CAMEL-CANAR. Together, our study establishes MAKR6 as a multifaceted regulator that couples transcriptional auxin signalling to PIN1 repolarization and coordinates multiple RLK-mediated signalling pathways during canalization. This provides mechanistic insights into auxin canalization and exemplifies a framework for exploring similar regulatory nodes in other developmental contexts.","lang":"eng"}],"department":[{"_id":"GradSch"},{"_id":"JiFr"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"author":[{"last_name":"Ge","id":"f43371a3-09ff-11eb-8013-bd0c6a2f6de8","orcid":"0000-0001-9381-3577","first_name":"Zengxiang","full_name":"Ge, Zengxiang"},{"last_name":"Koczka","first_name":"Lilla","full_name":"Koczka, Lilla"},{"full_name":"Mazur, Ewa","last_name":"Mazur","first_name":"Ewa"},{"full_name":"Molnar, Gergely","last_name":"Molnar","id":"34F1AF46-F248-11E8-B48F-1D18A9856A87","first_name":"Gergely"},{"first_name":"Dmitrii","id":"60466724-5355-11ee-ae5a-fa55e8f99c3d","last_name":"Vladimirtsev","full_name":"Vladimirtsev, Dmitrii"},{"full_name":"Kassem, Nada","last_name":"Kassem","first_name":"Nada"},{"full_name":"Ait Ikene, Sara","last_name":"Ait Ikene","id":"6a0bb896-6bad-11f1-9bef-906e9eb76034","first_name":"Sara"},{"full_name":"Fiedler, Lukas","first_name":"Lukas","id":"7c417475-8972-11ed-ae7b-8b674ca26986","last_name":"Fiedler"},{"full_name":"Friml, Jiří","first_name":"Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml"}]},{"project":[{"_id":"34bc2376-11ca-11ed-8bc3-9a3b3961a088","name":"Computational Discovery of Numerical Algorithms for Animation and Simulation of Natural Phenomena","grant_number":"101045083"}],"file_date_updated":"2026-06-23T09:07:22Z","file":[{"access_level":"open_access","checksum":"365f986db34e3fbce74089207599253b","relation":"main_file","date_created":"2026-06-23T09:07:22Z","file_name":"document(3).pdf","file_id":"22132","success":1,"content_type":"application/pdf","creator":"mly","file_size":14536575,"date_updated":"2026-06-23T09:07:22Z"}],"volume":45,"day":"24","article_processing_charge":"No","OA_type":"hybrid","oa_version":"Published Version","oa":1,"status":"public","publication_status":"accepted","doi":"10.1111/cgf.70516","ddc":["005"],"date_updated":"2026-06-24T05:49:08Z","month":"06","publication":"Computer Graphics Forum","has_accepted_license":"1","year":"2026","citation":{"chicago":"Wei, Ziyu , Christian Hafner, Aleksei Kalinov, Peter Synak, and Chris Wojtan. “Circles of Confidence for Multi-Label Geometry Completion.” In <i>Computer Graphics Forum</i>, Vol. 45. Wiley, n.d. <a href=\"https://doi.org/10.1111/cgf.70516\">https://doi.org/10.1111/cgf.70516</a>.","mla":"Wei, Ziyu, et al. “Circles of Confidence for Multi-Label Geometry Completion.” <i>Computer Graphics Forum</i>, vol. 45, no. 5, Wiley, doi:<a href=\"https://doi.org/10.1111/cgf.70516\">10.1111/cgf.70516</a>.","ista":"Wei Z, Hafner C, Kalinov A, Synak P, Wojtan C. Circles of confidence for multi-label geometry completion. Computer Graphics Forum. Eurographics: Symposium on Geometry Processing vol. 45.","short":"Z. Wei, C. Hafner, A. Kalinov, P. Synak, C. Wojtan, in:, Computer Graphics Forum, Wiley, n.d.","ama":"Wei Z, Hafner C, Kalinov A, Synak P, Wojtan C. Circles of confidence for multi-label geometry completion. In: <i>Computer Graphics Forum</i>. Vol 45. Wiley. doi:<a href=\"https://doi.org/10.1111/cgf.70516\">10.1111/cgf.70516</a>","apa":"Wei, Z., Hafner, C., Kalinov, A., Synak, P., &#38; Wojtan, C. (n.d.). Circles of confidence for multi-label geometry completion. In <i>Computer Graphics Forum</i> (Vol. 45). Bern, Switzerland: Wiley. <a href=\"https://doi.org/10.1111/cgf.70516\">https://doi.org/10.1111/cgf.70516</a>","ieee":"Z. Wei, C. Hafner, A. Kalinov, P. Synak, and C. Wojtan, “Circles of confidence for multi-label geometry completion,” in <i>Computer Graphics Forum</i>, Bern, Switzerland, vol. 45, no. 5."},"quality_controlled":"1","abstract":[{"text":"Inside–outside classification is widely used for geometry processing tasks such as surface reconstruction, geometry completion,\r\nand calculating signed distance fields. We introduce a new integral formulation of this problem, which assigns confidence\r\nscores that points are inside or outside, given incomplete boundary geometry. Even though our geometric construction does\r\nnot appear in previous work, we show that it is unexpectedly linked to both the well-established generalized winding number\r\n(GWN) and pseudonormal methods for geometry completion, and it provably reduces to either one of them for specific values\r\nof a control parameter. The results obtained with our method frequently outperform screened Poisson surface reconstruction\r\n(PSR), GWN, and the pseudonormal method in terms of quality, and are at least on par with them on all of our examples. Unlike\r\nthese methods, our algorithm naturally extends to the multi-label setting, in which regions with an arbitrary number of colors\r\nor physical materials can be reconstructed, and non-manifold features such as T-junctions may appear in the interface and\r\nboundary geometry","lang":"eng"}],"author":[{"last_name":"Wei","first_name":"Ziyu ","full_name":"Wei, Ziyu "},{"last_name":"Hafner","first_name":"Christian","id":"400429CC-F248-11E8-B48F-1D18A9856A87","full_name":"Hafner, Christian"},{"last_name":"Kalinov","id":"44b7120e-eb97-11eb-a6c2-e1557aa81d02","first_name":"Aleksei","orcid":"0000-0003-2189-3904","full_name":"Kalinov, Aleksei"},{"full_name":"Synak, Peter","last_name":"Synak","first_name":"Peter","id":"331776E2-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Wojtan","orcid":"0000-0001-6646-5546","id":"3C61F1D2-F248-11E8-B48F-1D18A9856A87","first_name":"Christopher J","full_name":"Wojtan, Christopher J"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"department":[{"_id":"ChWo"},{"_id":"GradSch"}],"title":"Circles of confidence for multi-label geometry completion","type":"conference","corr_author":"1","intvolume":"        45","_id":"22129","date_published":"2026-06-24T00:00:00Z","language":[{"iso":"eng"}],"OA_place":"publisher","issue":"5","date_created":"2026-06-23T09:08:41Z","conference":{"end_date":"2026-07-03","start_date":"2026-07-01","name":"Eurographics: Symposium on Geometry Processing","location":"Bern, Switzerland"},"publisher":"Wiley","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"publisher":"Springer Nature","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","intvolume":"         9","_id":"20840","article_number":"80","date_published":"2026-03-04T00:00:00Z","language":[{"iso":"eng"}],"acknowledgement":"We thank Gerard Higgins, Andrei Militaru, Nikolai Kiesel, and Markus Aspelmeyer for useful discussions on the topic of the figure-of-merit. We thank Teodor Strömberg for helping with the additional characterizations of the optical lever noise. We thank Johannes Fink and Scott Waitukaitis for their helpful feedback on the manuscript. This work was supported by Institute of Science and Technology Austria and the European Research Council under Grant No. 101087907 (ERC CoG QuHAMP).","OA_place":"publisher","date_created":"2025-12-21T11:39:04Z","scopus_import":"1","title":"One-milligram torsional pendulum toward experiments at the quantum-gravity interface","related_material":{"record":[{"id":"20842","relation":"research_data","status":"public"}]},"corr_author":"1","type":"journal_article","arxiv":1,"publication_identifier":{"eissn":["2399-3650"]},"abstract":[{"text":"Probing the possibility of entanglement generation through gravity offers a path to tackle the question of whether gravitational fields possess a quantum mechanical nature. A potential realization necessitates systems with low-frequency dynamics at an optimal mass scale, for which the microgram-to-milligram range is a strong contender. Here, after refining a figure-of-merit for the problem, we present a 1-milligram torsional pendulum operating at 18 Hz. We demonstrate laser cooling its motion from room temperature to 240 microkelvins, surpassing by over 20-fold the coldest motions attained for oscillators ranging from micrograms to kilograms. We quantify and contrast the utility of the current approach with other platforms. The achieved performance and large improvement potential highlight milligram-scale torsional pendulums as a powerful platform for precision measurements relevant to future studies at the quantum-gravity interface.","lang":"eng"}],"quality_controlled":"1","author":[{"first_name":"Sofya","id":"09501ff6-dca7-11ea-a8ae-b3e0b9166e80","orcid":"0000-0003-0582-2946","last_name":"Agafonova","full_name":"Agafonova, Sofya"},{"full_name":"Rosello, Pere","last_name":"Rosello","first_name":"Pere"},{"last_name":"Mekonnen","first_name":"Manuel","full_name":"Mekonnen, Manuel"},{"last_name":"Hosten","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","first_name":"Onur","orcid":"0000-0002-2031-204X","full_name":"Hosten, Onur"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"department":[{"_id":"GradSch"},{"_id":"OnHo"}],"has_accepted_license":"1","citation":{"ieee":"S. Agafonova, P. Rosello, M. Mekonnen, and O. Hosten, “One-milligram torsional pendulum toward experiments at the quantum-gravity interface,” <i>Communications Physics</i>, vol. 9. Springer Nature, 2026.","chicago":"Agafonova, Sofia, Pere Rosello, Manuel Mekonnen, and Onur Hosten. “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.” <i>Communications Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s42005-026-02514-w\">https://doi.org/10.1038/s42005-026-02514-w</a>.","ista":"Agafonova S, Rosello P, Mekonnen M, Hosten O. 2026. One-milligram torsional pendulum toward experiments at the quantum-gravity interface. Communications Physics. 9, 80.","mla":"Agafonova, Sofia, et al. “One-Milligram Torsional Pendulum toward Experiments at the Quantum-Gravity Interface.” <i>Communications Physics</i>, vol. 9, 80, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s42005-026-02514-w\">10.1038/s42005-026-02514-w</a>.","short":"S. Agafonova, P. Rosello, M. Mekonnen, O. Hosten, Communications Physics 9 (2026).","apa":"Agafonova, S., Rosello, P., Mekonnen, M., &#38; Hosten, O. (2026). One-milligram torsional pendulum toward experiments at the quantum-gravity interface. <i>Communications Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s42005-026-02514-w\">https://doi.org/10.1038/s42005-026-02514-w</a>","ama":"Agafonova S, Rosello P, Mekonnen M, Hosten O. One-milligram torsional pendulum toward experiments at the quantum-gravity interface. <i>Communications Physics</i>. 2026;9. doi:<a href=\"https://doi.org/10.1038/s42005-026-02514-w\">10.1038/s42005-026-02514-w</a>"},"year":"2026","external_id":{"arxiv":["2408.09445"]},"publication":"Communications Physics","month":"03","PlanS_conform":"1","status":"public","publication_status":"published","doi":"10.1038/s42005-026-02514-w","ddc":["530"],"date_updated":"2026-06-10T08:36:06Z","DOAJ_listed":"1","project":[{"name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics","_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6","grant_number":"101087907"}],"file_date_updated":"2026-03-16T10:07:46Z","file":[{"success":1,"file_name":"2026_CommunicationsPhysics_Agafonova.pdf","file_id":"21457","date_created":"2026-03-16T10:07:46Z","relation":"main_file","access_level":"open_access","checksum":"62e2175e7e3ad49260ae6a7b4e0860a2","date_updated":"2026-03-16T10:07:46Z","file_size":1901772,"creator":"dernst","content_type":"application/pdf"}],"volume":9,"day":"04","article_processing_charge":"Yes","OA_type":"gold","oa_version":"Published Version","oa":1},{"acknowledged_ssus":[{"_id":"LifeSc"},{"_id":"Bio"}],"month":"01","degree_awarded":"MS","citation":{"ieee":"D. Vladimirtsev, “Armadillo repeat only proteins are master regulators of plant cyclic-nucleotide gated channels,” Institute of Science and Technology Austria, 2026.","chicago":"Vladimirtsev, Dmitrii. “Armadillo Repeat Only Proteins Are Master Regulators of Plant Cyclic-Nucleotide Gated Channels.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-20964\">https://doi.org/10.15479/AT-ISTA-20964</a>.","short":"D. Vladimirtsev, Armadillo Repeat Only Proteins Are Master Regulators of Plant Cyclic-Nucleotide Gated Channels, Institute of Science and Technology Austria, 2026.","mla":"Vladimirtsev, Dmitrii. <i>Armadillo Repeat Only Proteins Are Master Regulators of Plant Cyclic-Nucleotide Gated Channels</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20964\">10.15479/AT-ISTA-20964</a>.","ista":"Vladimirtsev D. 2026. Armadillo repeat only proteins are master regulators of plant cyclic-nucleotide gated channels. Institute of Science and Technology Austria.","ama":"Vladimirtsev D. Armadillo repeat only proteins are master regulators of plant cyclic-nucleotide gated channels. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20964\">10.15479/AT-ISTA-20964</a>","apa":"Vladimirtsev, D. (2026). <i>Armadillo repeat only proteins are master regulators of plant cyclic-nucleotide gated channels</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20964\">https://doi.org/10.15479/AT-ISTA-20964</a>"},"supervisor":[{"first_name":"Jiří","orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","last_name":"Friml","full_name":"Friml, Jiří"}],"year":"2026","has_accepted_license":"1","oa_version":"Published Version","article_processing_charge":"No","day":"14","project":[{"name":"Cyclic nucleotides as second messengers in plants","_id":"8f347782-16d5-11f0-9cad-8c19706ee739","grant_number":"101142681"}],"file":[{"creator":"dvladimi","file_size":2867531,"date_updated":"2026-01-21T14:12:13Z","content_type":"application/pdf","embargo":"2027-01-01","embargo_to":"open_access","date_created":"2026-01-21T14:12:13Z","file_id":"21033","file_name":"2026_Vladimirtsev_Dmitrii_Thesis.pdf","access_level":"closed","checksum":"812857b2fbe3f6113bef22fd04bccd3e","relation":"main_file"},{"date_created":"2026-01-21T14:41:58Z","file_id":"21034","file_name":"Source Files.zip","access_level":"closed","checksum":"2b969f97f8d7461bea3d255f48c2219c","relation":"source_file","creator":"dvladimi","date_updated":"2026-01-28T12:38:19Z","file_size":25023066,"content_type":"application/x-zip-compressed"}],"file_date_updated":"2026-01-28T12:38:19Z","date_updated":"2026-04-07T11:41:44Z","ddc":["570"],"publication_status":"published","status":"public","doi":"10.15479/AT-ISTA-20964","OA_place":"publisher","date_created":"2026-01-09T09:22:48Z","language":[{"iso":"eng"}],"date_published":"2026-01-14T00:00:00Z","alternative_title":["ISTA Master’s Thesis"],"_id":"20964","page":"22","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Institute of Science and Technology Austria","department":[{"_id":"GradSch"},{"_id":"JiFr"}],"author":[{"first_name":"Dmitrii","id":"60466724-5355-11ee-ae5a-fa55e8f99c3d","last_name":"Vladimirtsev","full_name":"Vladimirtsev, Dmitrii"}],"corr_author":"1","type":"dissertation","publication_identifier":{"issn":["2791-4585"]},"related_material":{"record":[{"id":"20982","status":"public","relation":"part_of_dissertation"}]},"title":"Armadillo repeat only proteins are master regulators of plant cyclic-nucleotide gated channels"},{"date_updated":"2026-01-20T07:33:32Z","PlanS_conform":"1","status":"public","publication_status":"epub_ahead","doi":"10.1016/j.cub.2025.12.025","ddc":["570","577"],"OA_type":"hybrid","oa_version":"Published Version","oa":1,"project":[{"grant_number":"819603","call_identifier":"H2020","_id":"0aacfa84-070f-11eb-9043-d7eb2c709234","name":"Learning the shape of synaptic plasticity rules for neuronal architectures and function through machine learning."}],"article_processing_charge":"Yes (in subscription journal)","day":"12","citation":{"ieee":"J. S. Calderon Garcia, G. Costalunga, T. P. Vogels, and D. Vallentin, “Interplay between syllable duration and pitch during whistle matching in wild nightingales,” <i>Current Biology</i>. Elsevier, 2026.","apa":"Calderon Garcia, J. S., Costalunga, G., Vogels, T. P., &#38; Vallentin, D. (2026). Interplay between syllable duration and pitch during whistle matching in wild nightingales. <i>Current Biology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">https://doi.org/10.1016/j.cub.2025.12.025</a>","ama":"Calderon Garcia JS, Costalunga G, Vogels TP, Vallentin D. Interplay between syllable duration and pitch during whistle matching in wild nightingales. <i>Current Biology</i>. 2026. doi:<a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">10.1016/j.cub.2025.12.025</a>","chicago":"Calderon Garcia, Juan Sebastian, Giacomo Costalunga, Tim P Vogels, and Daniela Vallentin. “Interplay between Syllable Duration and Pitch during Whistle Matching in Wild Nightingales.” <i>Current Biology</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">https://doi.org/10.1016/j.cub.2025.12.025</a>.","ista":"Calderon Garcia JS, Costalunga G, Vogels TP, Vallentin D. 2026. Interplay between syllable duration and pitch during whistle matching in wild nightingales. Current Biology.","mla":"Calderon Garcia, Juan Sebastian, et al. “Interplay between Syllable Duration and Pitch during Whistle Matching in Wild Nightingales.” <i>Current Biology</i>, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.cub.2025.12.025\">10.1016/j.cub.2025.12.025</a>.","short":"J.S. Calderon Garcia, G. Costalunga, T.P. Vogels, D. Vallentin, Current Biology (2026)."},"year":"2026","has_accepted_license":"1","publication":"Current Biology","month":"01","ec_funded":1,"type":"journal_article","publication_identifier":{"eissn":["1879-0445"],"issn":["0960-9822"]},"main_file_link":[{"url":"https://doi.org/10.1016/j.cub.2025.12.025","open_access":"1"}],"title":"Interplay between syllable duration and pitch during whistle matching in wild nightingales","author":[{"id":"1271b54b-dbcd-11ea-9d1d-d92da838fe2c","first_name":"Juan Sebastian","last_name":"Calderon Garcia","full_name":"Calderon Garcia, Juan Sebastian"},{"first_name":"Giacomo","last_name":"Costalunga","full_name":"Costalunga, Giacomo"},{"first_name":"Tim P","id":"CB6FF8D2-008F-11EA-8E08-2637E6697425","orcid":"0000-0003-3295-6181","last_name":"Vogels","full_name":"Vogels, Tim P"},{"full_name":"Vallentin, Daniela","first_name":"Daniela","last_name":"Vallentin"}],"department":[{"_id":"GradSch"},{"_id":"TiVo"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"abstract":[{"lang":"eng","text":"During complex vocal interactions, different features of acoustic stimuli are integrated to produce appropriate vocal responses,1 such as copying sounds during vocal matching behavior in some animals.2,3,4,5,6,7,8,9,10,11,12 However, little is known about the interplay and possible trade-offs between the different temporal and spectral acoustic features during these vocal exchanges.2,13,14 Nightingales can flexibly match the pitch of their tonal “whistle songs” in real time during counter-singing duels.15,16 Here, we show that the syllable duration of whistle playbacks could alter the song responses of wild nightingales, causing their whistle duration distribution to shift toward the presented stimulus duration. When exposed to whistle playbacks featuring unnatural combinations of pitch and duration, nightingales demonstrate a flexible trade-off between pitch matching and temporal imitation, yet they are constrained by their vocal repertoire. They selectively adapted their vocal responses to approximate these novel stimuli, aligning them with their natural whistle repertoire. We developed a computational model of nightingale whistle-matching behavior that revealed a hierarchical organization of acoustic feature production. During whistle matching, the feature integration process is constrained by the duration of syllables, and pitch matching follows within this temporal framework, forcing a trade-off between the two features. Our findings reveal a complex interplay between the spectral and temporal domains that shapes song-matching behavior."}],"quality_controlled":"1","publisher":"Elsevier","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","language":[{"iso":"eng"}],"acknowledgement":"We would like to thank J. Benichov and N. Hein for their help with fieldwork; M. Ramadas for helping with the segmentation analysis; T. Eliav, C. Chintaluri, G. Tkacik, and A. Navas for providing helpful comments to the project and manuscript; and A. Costalunga for the drawings of nightingales. Funding sources: The Joachim Herz Stiftung Add-on Fellowships for Interdisciplinary Life Science, awarded to G.C.; the ERC Consolidator Grant 819603 SYNAPSEEK, awarded to T.P.V.; and DFG Research Unit 5768–532521431, DFG Research Grant-547921981, DFG SFB 1315–327654276, and the ERC Starting Grant 757459 MIDNIGHT, awarded to D.V.","date_created":"2026-01-14T12:00:29Z","OA_place":"publisher","scopus_import":"1","_id":"20986","date_published":"2026-01-12T00:00:00Z"},{"publication_identifier":{"isbn":["978-3-99078-077-0"],"issn":["2663-337X"]},"license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","type":"dissertation","corr_author":"1","related_material":{"record":[{"relation":"research_data","status":"public","id":"18498"},{"relation":"part_of_dissertation","status":"public","id":"18491"}]},"title":"The genomic architecture of local adaptation in introduced populations","department":[{"_id":"GradSch"},{"_id":"NiBa"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","image":"/images/cc_by_nc_sa.png","short":"CC BY-NC-SA (4.0)","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"author":[{"last_name":"Garcia Castillo","id":"ae681a14-dc74-11ea-a0a7-c6ef18161701","first_name":"Diego Fernando","full_name":"Garcia Castillo, Diego Fernando"}],"abstract":[{"text":"Rapid local adaptation to new environments is critical for species persistence, especially in introduced populations. The evolutionary success of these populations is fundamentally dictated by the organization of genetic variation—the genomic architecture—in the face of severe demographic constraints, such as the founder effects and genetic bottlenecks that frequently accompany colonization. A central question in evolutionary biology is whether rapid adaptation relies on major-effect loci, such as chromosomal inversions, or on many small-effect loci dispersed across the genome. Furthermore, the genomic architecture strongly influences the extent to which evolutionary outcomes are predictable. Using introduced populations of the marine snail, Littorina saxatilis, as a model, this thesis investigates how genetic variation and genomic structure drive adaptation following introduction. We employed a population genomics approach on experimentally and accidentally introduced populations to dissect the specific genomic features that underpin divergence in newly colonized environments.\r\n\r\nIn Chapter 2, we tested the predictability of local adaptation through an uncommon 30-year transplant experiment in nature. By distinguishing allele and chromosomal inversion frequency changes from neutral expectations, we found that evolutionary change was highly predictable at the macro-scale (phenotypes and chromosomal inversions), but less robust at the level of individual collinear loci. This result demonstrates that evolution can be predictable when a population possesses sufficient standing genetic variation (SGV), with chromosomal inversions acting as key integrated units that facilitate a rapid response to selection. Building on this, Chapter 3 applied whole-genome sequencing to three accidentally introduced populations (Venice, San Francisco, and Redwood City) to investigate their likely source and genomic patterns of divergence. We identified genomic regions of remarkable divergence potentially associated with local adaptation, and likely fuelled by SGV, while explicitly acknowledging the difficulty in disentangling selection signals from the genome-wide effects of demographic processes. Furthermore, we found that the divergence patterns relied extensively on the collinear genome in these introduced populations, and less clearly on the chromosomal inversions. This observation contrasts with local adaptation observed in the experimental system that relied on both collinear loci and highly selected chromosomal inversions, highlighting how demographic history and genomic architecture influence the detectable signature of local adaptation.\r\n\r\nA major limitation to conducting large-scale comparative evolutionary studies is the lack of data standardization, which prevents the integration of community knowledge and high-resolution environmental and genetic data. Chapter 4 addresses this by developing a community database for the Littorina system. This platform implements standardized protocols for the integration of diverse phenotypic and environmental data from multiple Littorina species. Likewise, the platform also centralizes the availability of associated genomic data through links to external repositories. This database represents a crucial tool to test complex, large-scale evolutionary hypotheses.\r\n\r\nCollectively, this thesis strongly reinforces the fundamental importance of SGV as the raw material for successful local adaptation, a conclusion supported by evidence in both experimental and accidental introductions. Furthermore, this work highlights the critical role of the genomic architecture—specifically chromosomal inversions—in driving the predictability and effectiveness of adaptive responses. Our findings underscore how the interplay between SGV and genomic architecture dictates the trajectory and detectability of evolution in colonizing populations, while simultaneously providing a necessary tool to advance comparative evolutionary genomics in emerging model organisms.","lang":"eng"}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Institute of Science and Technology Austria","date_created":"2026-01-16T09:47:59Z","OA_place":"publisher","acknowledgement":"I acknowledge the funding agencies 1Norwegian Research Council RCN project 315287.\r\n2The FIASCO project \"Illuminating range shifts through evolutionary FIASCO: contrasting\r\nFaIling And Successful ColOnizations in replicated wild populations\", funded by the\r\nEuropean Union - Next Generation EU (Piano Nazionale di Ripresa e Resilienza - MUR\r\ncode: P202229JBC, CUP: C53D23007100001). 3Ecotypic formation in Littorina saxatilis\r\nin the Western Atlantic and comparisons across the North Atlantic. University of\r\nGothenburg Research Travel Grant, Tjarno Marine Laboratory, Sweden. $3023 (2018).\r\n4JIN project (Young Researchers, Spanish Ministry of Science, RTI2018-101274-J-I00)","language":[{"iso":"eng"}],"date_published":"2026-01-16T00:00:00Z","page":"199","_id":"20991","alternative_title":["ISTA Thesis"],"date_updated":"2026-04-16T12:20:37Z","ddc":["576"],"doi":"10.15479/AT-ISTA-20991","publication_status":"published","status":"public","oa":1,"oa_version":"Published Version","article_processing_charge":"No","day":"16","file":[{"content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","creator":"dgarciac","date_updated":"2026-01-16T12:25:13Z","file_size":22456421,"access_level":"closed","checksum":"841f1bc073d667125729b2a017f8c37a","relation":"source_file","date_created":"2026-01-16T12:25:13Z","file_name":"2026_Garcia_Diego_Thesis.docx","file_id":"20996"},{"access_level":"open_access","checksum":"a1f33d4f183ce7072eee42a6ccf5340b","relation":"main_file","date_created":"2026-01-16T12:25:13Z","success":1,"file_name":"2026_Garcia_Diego_Thesis.pdf","file_id":"20997","content_type":"application/pdf","creator":"dgarciac","date_updated":"2026-01-16T12:25:13Z","file_size":9556719},{"date_created":"2026-01-16T13:08:14Z","file_name":"2026_DiegoGarcia_LittorinaDB Source Code and Protocols.rar","description":"Source code of the PostgreSQL database, front-end and back-end of the LittorinaDB web application developed as a product of the 4th chapter of the thesis.","file_id":"20998","access_level":"closed","checksum":"98a80691067174c30fe53f38ce7344e6","relation":"supplementary_material","creator":"dgarciac","file_size":54491433,"date_updated":"2026-01-16T13:08:14Z","content_type":"application/x-compressed"},{"content_type":"application/x-compressed","creator":"dgarciac","file_size":7982811,"date_updated":"2026-01-16T13:08:14Z","access_level":"open_access","checksum":"99a3cab2fa36666b9a92eefc27d586da","relation":"supplementary_material","date_created":"2026-01-16T13:08:14Z","file_name":"2026_DiegoGarcia_Thesis-Supplementary_Material.rar","file_id":"20999"},{"file_id":"21000","file_name":"README.txt","date_created":"2026-01-16T13:08:59Z","relation":"supplementary_material","checksum":"255fdf56b2932c46bf27c63aa6106a4f","access_level":"open_access","file_size":732,"date_updated":"2026-01-16T13:08:59Z","creator":"dgarciac","content_type":"text/plain"}],"file_date_updated":"2026-01-16T13:08:59Z","supervisor":[{"last_name":"Barton","first_name":"Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H"},{"full_name":"Westram, Anja M","last_name":"Westram","orcid":"0000-0003-1050-4969","first_name":"Anja M","id":"3C147470-F248-11E8-B48F-1D18A9856A87"}],"citation":{"ieee":"D. F. Garcia Castillo, “The genomic architecture of local adaptation in introduced populations,” Institute of Science and Technology Austria, 2026.","chicago":"Garcia Castillo, Diego Fernando. “The Genomic Architecture of Local Adaptation in Introduced Populations.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-20991\">https://doi.org/10.15479/AT-ISTA-20991</a>.","short":"D.F. Garcia Castillo, The Genomic Architecture of Local Adaptation in Introduced Populations, Institute of Science and Technology Austria, 2026.","mla":"Garcia Castillo, Diego Fernando. <i>The Genomic Architecture of Local Adaptation in Introduced Populations</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20991\">10.15479/AT-ISTA-20991</a>.","ista":"Garcia Castillo DF. 2026. The genomic architecture of local adaptation in introduced populations. Institute of Science and Technology Austria.","ama":"Garcia Castillo DF. The genomic architecture of local adaptation in introduced populations. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-20991\">10.15479/AT-ISTA-20991</a>","apa":"Garcia Castillo, D. F. (2026). <i>The genomic architecture of local adaptation in introduced populations</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-20991\">https://doi.org/10.15479/AT-ISTA-20991</a>"},"year":"2026","has_accepted_license":"1","degree_awarded":"PhD","month":"01"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"American Chemical Society","article_type":"letter_note","scopus_import":"1","date_created":"2026-01-18T23:02:43Z","issue":"1","acknowledgement":"This publication has emanated from research conducted with the financial support of Taighde Éireann-Research Ireland under Grant number 22/FFP-P/11591. C.F. and M.I. would like to acknowledge the financial support of ISTA and the Werner Siemens Foundation. N.N.P. acknowledges the financial support of AMBER under grant number 12/rc/2278_p2.","language":[{"iso":"eng"}],"date_published":"2026-01-09T00:00:00Z","page":"481-488","_id":"21001","intvolume":"        11","publication_identifier":{"eissn":["2380-8195"]},"type":"journal_article","title":"Layered alkali-copper selenides: Deciphering thermoelectric properties and reaction pathways for nanostructuring β-CsCu5Se3","department":[{"_id":"MaIb"},{"_id":"GradSch"}],"author":[{"last_name":"Patil","first_name":"Niraj Nitish","full_name":"Patil, Niraj Nitish"},{"last_name":"Wu","first_name":"Ruiqi","full_name":"Wu, Ruiqi"},{"first_name":"Christine","id":"bd3fceba-dc74-11ea-a0a7-c17f71817366","last_name":"Fiedler","full_name":"Fiedler, Christine"},{"first_name":"Nilotpal","last_name":"Kapuria","full_name":"Kapuria, Nilotpal"},{"first_name":"Bingfei","last_name":"Nan","full_name":"Nan, Bingfei"},{"last_name":"Navita","orcid":"0000-0001-7408-8197","first_name":"Navita","id":"6ebe278d-ba0b-11ee-8184-f34cdc671de4","full_name":"Navita, Navita"},{"first_name":"Andreu","last_name":"Cabot","full_name":"Cabot, Andreu"},{"last_name":"Ibáñez","id":"43C61214-F248-11E8-B48F-1D18A9856A87","first_name":"Maria","orcid":"0000-0001-5013-2843","full_name":"Ibáñez, Maria"},{"full_name":"Ryan, Kevin M.","first_name":"Kevin M.","last_name":"Ryan"},{"first_name":"Alex M.","last_name":"Ganose","full_name":"Ganose, Alex M."},{"full_name":"Singh, Shalini","first_name":"Shalini","last_name":"Singh"}],"abstract":[{"lang":"eng","text":"Copper chalcogenides offer high charge mobility and low lattice thermal conductivity but suffer from structural instability due to dynamic Cu+ migration. Here, we report a colloidal hot-injection synthesis of ternary cesium copper selenide (CsCu5Se3) nanocrystals (NCs), achieving precise control over phase, size, and morphology through tailored precursor-ligand modulation. This strategy enabled systematic exploration of stable and metastable Cs–Cu–Se phases and mechanistic investigation of nucleation and growth, providing insight into phase modulation and dimensional control at the nanoscale. CsCu5Se3 NCs exhibit low lattice thermal conductivity (∼0.5 Wm–1K–1) and an experimental zT of 0.27 at 718 K. Complementary first-principles calculations, consistent with experimental electronic and optical responses, predict a zT of 1.05 at 1000 K. These findings elucidate the formation dynamics of CsCu5Se3 and establish ABZ (A = alkali, B = metal, Z = chalcogen) NCs as tunable platforms for advanced functional applications."}],"quality_controlled":"1","citation":{"ama":"Patil NN, Wu R, Fiedler C, et al. Layered alkali-copper selenides: Deciphering thermoelectric properties and reaction pathways for nanostructuring β-CsCu5Se3. <i>ACS Energy Letters</i>. 2026;11(1):481-488. doi:<a href=\"https://doi.org/10.1021/acsenergylett.5c02909\">10.1021/acsenergylett.5c02909</a>","apa":"Patil, N. N., Wu, R., Fiedler, C., Kapuria, N., Nan, B., Jakhar, N., … Singh, S. (2026). Layered alkali-copper selenides: Deciphering thermoelectric properties and reaction pathways for nanostructuring β-CsCu5Se3. <i>ACS Energy Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acsenergylett.5c02909\">https://doi.org/10.1021/acsenergylett.5c02909</a>","ista":"Patil NN, Wu R, Fiedler C, Kapuria N, Nan B, Jakhar N, Cabot A, Ibáñez M, Ryan KM, Ganose AM, Singh S. 2026. Layered alkali-copper selenides: Deciphering thermoelectric properties and reaction pathways for nanostructuring β-CsCu5Se3. ACS Energy Letters. 11(1), 481–488.","mla":"Patil, Niraj Nitish, et al. “Layered Alkali-Copper Selenides: Deciphering Thermoelectric Properties and Reaction Pathways for Nanostructuring β-CsCu5Se3.” <i>ACS Energy Letters</i>, vol. 11, no. 1, American Chemical Society, 2026, pp. 481–88, doi:<a href=\"https://doi.org/10.1021/acsenergylett.5c02909\">10.1021/acsenergylett.5c02909</a>.","short":"N.N. Patil, R. Wu, C. Fiedler, N. Kapuria, B. Nan, N. Jakhar, A. Cabot, M. Ibáñez, K.M. Ryan, A.M. Ganose, S. Singh, ACS Energy Letters 11 (2026) 481–488.","chicago":"Patil, Niraj Nitish, Ruiqi Wu, Christine Fiedler, Nilotpal Kapuria, Bingfei Nan, Navita Jakhar, Andreu Cabot, et al. “Layered Alkali-Copper Selenides: Deciphering Thermoelectric Properties and Reaction Pathways for Nanostructuring β-CsCu5Se3.” <i>ACS Energy Letters</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acsenergylett.5c02909\">https://doi.org/10.1021/acsenergylett.5c02909</a>.","ieee":"N. N. Patil <i>et al.</i>, “Layered alkali-copper selenides: Deciphering thermoelectric properties and reaction pathways for nanostructuring β-CsCu5Se3,” <i>ACS Energy Letters</i>, vol. 11, no. 1. American Chemical Society, pp. 481–488, 2026."},"year":"2026","month":"01","publication":"ACS Energy Letters","date_updated":"2026-01-19T08:43:21Z","doi":"10.1021/acsenergylett.5c02909","status":"public","publication_status":"published","oa_version":"None","OA_type":"closed access","article_processing_charge":"No","day":"09","volume":11,"project":[{"name":"HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of Semiconductors for Waste Heat Recovery","_id":"9B8F7476-BA93-11EA-9121-9846C619BF3A"}]},{"abstract":[{"lang":"eng","text":"Modern experimental methods in programmable self-assembly make it possible to precisely design particle concentrations, shapes and interactions. However, more physical insight is needed before we can take full advantage of this vast design space to assemble nanostructures with complex form and function. Here we show how a substantial part of this design space can be quickly and comprehensively understood by identifying a class of thermodynamic constraints that act on it. These thermodynamic constraints form a high-dimensional convex polyhedron that determines which nanostructures can be assembled at high equilibrium yield and reveals limitations that govern the coexistence of structures. We validate our predictions through detailed, quantitative assembly experiments of nanoscale particles synthesized using DNA origami. Our results uncover physical relationships underpinning many-component programmable self-assembly in equilibrium and form the basis for robust inverse design, applicable to various systems from biological protein complexes to synthetic nanomachines."}],"quality_controlled":"1","department":[{"_id":"CaGo"},{"_id":"GradSch"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"author":[{"first_name":"Maximilian","id":"5eb8629e-15b2-11ec-abd3-e6f3e5e01f32","last_name":"Hübl","full_name":"Hübl, Maximilian"},{"first_name":"Thomas E.","last_name":"Videbæk","full_name":"Videbæk, Thomas E."},{"last_name":"Hayakawa","first_name":"Daichi","full_name":"Hayakawa, Daichi"},{"last_name":"Rogers","first_name":"W. Benjamin","full_name":"Rogers, W. Benjamin"},{"full_name":"Goodrich, Carl Peter","last_name":"Goodrich","first_name":"Carl Peter","orcid":"0000-0002-1307-5074","id":"EB352CD2-F68A-11E9-89C5-A432E6697425"}],"related_material":{"link":[{"description":"News on ISTA website","url":"https://ista.ac.at/en/news/behind-natures-blueprints/","relation":"press_release"}]},"title":"A polyhedral structure controls programmable self-assembly","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41567-025-03120-3"}],"corr_author":"1","type":"journal_article","publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"date_published":"2026-01-08T00:00:00Z","_id":"21006","OA_place":"publisher","date_created":"2026-01-20T10:02:19Z","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"We thank B. Isaac and A. Tiano for their technical support with the electron microscopy and S. Waitukaitis for helpful comments on the manuscript. The TEM images were prepared and imaged at the Brandeis Electron Microscopy facility. This work was supported by the Gesellschaft für Forschungsförderung Niederösterreich under project FTI23-G-011 (M.C.H. and C.P.G.), the Brandeis University Materials Research Science and Engineering Center (MRSEC) under grant number NSF DMR-2011846 (T.E.V., D.H. and W.B.R.) and the Smith Family Foundation (W.B.R.). Open access funding provided by Institute of Science and Technology (IST Austria).","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","publisher":"Springer Nature","article_type":"original","day":"08","article_processing_charge":"Yes (via OA deal)","project":[{"name":"Dynamically reconfigurable self-assembly with triangular DNA-origami bricks","_id":"8dd93da8-16d5-11f0-9cad-d2c70200d9a5","grant_number":"FTI23-G-011"}],"oa":1,"OA_type":"hybrid","oa_version":"Published Version","ddc":["570","540"],"PlanS_conform":"1","status":"public","publication_status":"epub_ahead","doi":"10.1038/s41567-025-03120-3","date_updated":"2026-04-28T11:56:45Z","publication":"Nature Physics","month":"01","has_accepted_license":"1","year":"2026","citation":{"ieee":"M. Hübl, T. E. Videbæk, D. Hayakawa, W. B. Rogers, and C. P. Goodrich, “A polyhedral structure controls programmable self-assembly,” <i>Nature Physics</i>. Springer Nature, 2026.","mla":"Hübl, Maximilian, et al. “A Polyhedral Structure Controls Programmable Self-Assembly.” <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41567-025-03120-3\">10.1038/s41567-025-03120-3</a>.","ista":"Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. 2026. A polyhedral structure controls programmable self-assembly. Nature Physics.","short":"M. Hübl, T.E. Videbæk, D. Hayakawa, W.B. Rogers, C.P. Goodrich, Nature Physics (2026).","chicago":"Hübl, Maximilian, Thomas E. Videbæk, Daichi Hayakawa, W. Benjamin Rogers, and Carl Peter Goodrich. “A Polyhedral Structure Controls Programmable Self-Assembly.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03120-3\">https://doi.org/10.1038/s41567-025-03120-3</a>.","ama":"Hübl M, Videbæk TE, Hayakawa D, Rogers WB, Goodrich CP. A polyhedral structure controls programmable self-assembly. <i>Nature Physics</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41567-025-03120-3\">10.1038/s41567-025-03120-3</a>","apa":"Hübl, M., Videbæk, T. E., Hayakawa, D., Rogers, W. B., &#38; Goodrich, C. P. (2026). A polyhedral structure controls programmable self-assembly. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03120-3\">https://doi.org/10.1038/s41567-025-03120-3</a>"}},{"has_accepted_license":"1","citation":{"ieee":"A. Bena and B. Pieber, “Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings,” <i>ACS Catalysis</i>, vol. 16, no. 2. American Chemical Society, pp. 866–881, 2026.","chicago":"Bena, Aleksander, and Bartholomäus Pieber. “Advances in NiI/NiIII-Catalyzed C(Sp2)–Heteroatom Cross-Couplings.” <i>ACS Catalysis</i>. American Chemical Society, 2026. <a href=\"https://doi.org/10.1021/acscatal.5c07964\">https://doi.org/10.1021/acscatal.5c07964</a>.","mla":"Bena, Aleksander, and Bartholomäus Pieber. “Advances in NiI/NiIII-Catalyzed C(Sp2)–Heteroatom Cross-Couplings.” <i>ACS Catalysis</i>, vol. 16, no. 2, American Chemical Society, 2026, pp. 866–81, doi:<a href=\"https://doi.org/10.1021/acscatal.5c07964\">10.1021/acscatal.5c07964</a>.","short":"A. Bena, B. Pieber, ACS Catalysis 16 (2026) 866–881.","ista":"Bena A, Pieber B. 2026. Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. ACS Catalysis. 16(2), 866–881.","apa":"Bena, A., &#38; Pieber, B. (2026). Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. <i>ACS Catalysis</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acscatal.5c07964\">https://doi.org/10.1021/acscatal.5c07964</a>","ama":"Bena A, Pieber B. Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings. <i>ACS Catalysis</i>. 2026;16(2):866-881. doi:<a href=\"https://doi.org/10.1021/acscatal.5c07964\">10.1021/acscatal.5c07964</a>"},"year":"2026","month":"01","publication":"ACS Catalysis","doi":"10.1021/acscatal.5c07964","status":"public","publication_status":"published","PlanS_conform":"1","ddc":["540"],"date_updated":"2026-01-21T09:15:16Z","project":[{"_id":"8f1d607d-16d5-11f0-9cad-ab453295ba5e","name":"Photoactive ligands for transformative nickel catalysis","grant_number":"PAT 1250924"}],"file_date_updated":"2026-01-21T09:12:10Z","file":[{"date_updated":"2026-01-21T09:12:10Z","file_size":3797064,"creator":"dernst","content_type":"application/pdf","success":1,"file_name":"2026_ACSCatalysis_Bena.pdf","file_id":"21030","date_created":"2026-01-21T09:12:10Z","relation":"main_file","access_level":"open_access","checksum":"05743d6d7b4bae37aad1a91471123032"}],"day":"16","article_processing_charge":"Yes (via OA deal)","volume":16,"oa_version":"Published Version","OA_type":"hybrid","oa":1,"publisher":"American Chemical Society","article_type":"original","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","page":"866-881","intvolume":"        16","_id":"21008","date_published":"2026-01-16T00:00:00Z","acknowledgement":"We gratefully acknowledge the Institute of Science and Technology Austria for generous financial support. B.P. acknowledges the Austrian Science Fund (PAT 1250924) for funding.","language":[{"iso":"eng"}],"scopus_import":"1","OA_place":"publisher","date_created":"2026-01-20T10:04:57Z","issue":"2","title":"Advances in NiI/NiIII-catalyzed C(sp2)–heteroatom cross-couplings","publication_identifier":{"eissn":["2155-5435"]},"type":"journal_article","corr_author":"1","quality_controlled":"1","abstract":[{"text":"C(sp2)–heteroatom couplings operating via NiI/NiIII catalysis have emerged as an alternative to canonical Pd0/PdII systems that require complex ligand architectures. Despite intensive research efforts during the past decade, catalytic methods employing this approach are still mostly confined to activated starting materials and require high catalyst loadings due to the low catalytic activity of NiI and undesired catalyst deactivation events. This article highlights recent advances in the field toward solving these long-standing challenges. We survey strategies that streamline the generation of catalytically competent NiI species from bench-stable NiII precatalysts, and discuss mechanistic studies that shed light on deactivation pathways and the rate-determining oxidative addition of aryl halides. In the final section, we highlight recently developed synthetic methodologies, which provide evidence that limitations can indeed be addressed by working at elevated temperatures, employing alternative electrophiles, harnessing the benefits of additives, or fine-tuning the metal’s reactivity through the ligand field.","lang":"eng"}],"author":[{"full_name":"Bena, Aleksander","id":"4197c39e-e8ec-11ed-86cb-afed934cd664","first_name":"Aleksander","last_name":"Bena"},{"id":"93e5e5b2-0da6-11ed-8a41-af589a024726","first_name":"Bartholomäus","orcid":"0000-0001-8689-388X","last_name":"Pieber","full_name":"Pieber, Bartholomäus"}],"department":[{"_id":"BaPi"},{"_id":"GradSch"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"}},{"ec_funded":1,"acknowledged_ssus":[{"_id":"ScienComp"}],"month":"01","publication":"Journal of Advances in Modeling Earth Systems","has_accepted_license":"1","year":"2026","citation":{"ama":"GOSWAMI BB, Lu Z, Muller CJ. Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. <i>Journal of Advances in Modeling Earth Systems</i>. 2026;18(1). doi:<a href=\"https://doi.org/10.1029/2024ms004576\">10.1029/2024ms004576</a>","apa":"GOSWAMI, B. B., Lu, Z., &#38; Muller, C. J. (2026). Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. <i>Journal of Advances in Modeling Earth Systems</i>. Wiley. <a href=\"https://doi.org/10.1029/2024ms004576\">https://doi.org/10.1029/2024ms004576</a>","short":"B.B. GOSWAMI, Z. Lu, C.J. Muller, Journal of Advances in Modeling Earth Systems 18 (2026).","mla":"GOSWAMI, BIDYUT B., et al. “Convective Self‐aggregation in Diurnally Oscillating Sea Surface Temperature and Solar Forcing Experiments.” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 1, e2024MS004576, Wiley, 2026, doi:<a href=\"https://doi.org/10.1029/2024ms004576\">10.1029/2024ms004576</a>.","ista":"GOSWAMI BB, Lu Z, Muller CJ. 2026. Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments. Journal of Advances in Modeling Earth Systems. 18(1), e2024MS004576.","chicago":"GOSWAMI, BIDYUT B, Ziyin Lu, and Caroline J Muller. “Convective Self‐aggregation in Diurnally Oscillating Sea Surface Temperature and Solar Forcing Experiments.” <i>Journal of Advances in Modeling Earth Systems</i>. Wiley, 2026. <a href=\"https://doi.org/10.1029/2024ms004576\">https://doi.org/10.1029/2024ms004576</a>.","ieee":"B. B. GOSWAMI, Z. Lu, and C. J. Muller, “Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments,” <i>Journal of Advances in Modeling Earth Systems</i>, vol. 18, no. 1. Wiley, 2026."},"volume":18,"article_processing_charge":"Yes","day":"12","file_date_updated":"2026-01-21T08:39:01Z","project":[{"call_identifier":"H2020","_id":"629205d8-2b32-11ec-9570-e1356ff73576","name":"Organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","grant_number":"805041"}],"file":[{"date_created":"2026-01-21T08:39:01Z","file_name":"2026_JAMES_Goswami.pdf","file_id":"21027","success":1,"checksum":"6ea369e3b46bea58efab4f38b6c671a7","access_level":"open_access","relation":"main_file","creator":"dernst","file_size":19509786,"date_updated":"2026-01-21T08:39:01Z","content_type":"application/pdf"}],"oa":1,"OA_type":"gold","oa_version":"Published Version","ddc":["550"],"status":"public","publication_status":"published","PlanS_conform":"1","doi":"10.1029/2024ms004576","DOAJ_listed":"1","date_updated":"2026-01-21T08:41:19Z","date_published":"2026-01-12T00:00:00Z","intvolume":"        18","_id":"21013","article_number":"e2024MS004576","issue":"1","date_created":"2026-01-20T10:08:54Z","OA_place":"publisher","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"The authors gratefully acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041). This research was supported by the Scientific Service Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp). We are grateful to three anonymous reviewer(s) for their insightful suggestions that have improved the quality of our manuscript. Open Access funding provided by Institute of Science and Technology Austria/KEMÖ.","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Wiley","article_type":"original","quality_controlled":"1","abstract":[{"lang":"eng","text":"We have addressed convective self‐aggregation (CSA) in steady and oscillating sea surface temperature (SST) and solar radiation (SOLIN) cloud‐resolving model simulations in a non‐rotating radiative‐convective equilibrium (RCE) framework. Our experiment designs are motivated by land‐ocean heterogeneity of atmospheric convection. The steady and oscillating forcings are idealizations of ocean and land conditions, respectively, based on their differences in heat capacities. In both kinds of simulations, the diurnal mean SST and SOLIN are the same, and both SST and SOLIN are only varied in time (i.e., they are spatially homogeneous at any given time). We find that diurnally oscillating forcing accelerates CSA. Stronger long‐wave cooling in dry regions at night and during the warm SST phase (late afternoon) both allow the long‐wave feedback, known to favor aggregation, to intensify compared to steady forcing simulations. In addition to the long‐wave, reduced short‐wave warming in dry regions (during the day) further enhances radiative cooling there compared to moist regions. Overall, the radiative cooling is enhanced in dry regions compared to neighboring moist convective regions. A dry subsidence is driven by this net radiative (short‐wave plus long‐wave) cooling, consistent with earlier work on CSA. Stronger radiative cooling allows stronger subsidence which allows low‐level circulation to more efficiently transport moisture and energy up‐gradient, driving convection to aggregate faster. We also note a sensitivity of our experimental setup to initial conditions, more so at warmer SST. This stochastic behavior might be critical in reconciling the differences of opinion regarding the response of convection aggregation to oscillating SST forcing."}],"department":[{"_id":"CaMu"},{"_id":"BjHo"},{"_id":"GradSch"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"},"author":[{"id":"3a4ac09c-6d61-11ec-bf66-884cde66b64b","first_name":"BIDYUT B","orcid":"0000-0001-8602-3083","last_name":"GOSWAMI","full_name":"GOSWAMI, BIDYUT B"},{"full_name":"Lu, Ziyin","id":"a6e549c6-8972-11ed-ae7b-a336d97ac043","orcid":"0009-0008-5320-7730","first_name":"Ziyin","last_name":"Lu"},{"id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","first_name":"Caroline J","orcid":"0000-0001-5836-5350","last_name":"Muller","full_name":"Muller, Caroline J"}],"title":"Convective self‐aggregation in diurnally oscillating sea surface temperature and solar forcing experiments","corr_author":"1","type":"journal_article","publication_identifier":{"eissn":["1942-2466"]}},{"month":"01","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"ScienComp"}],"citation":{"ieee":"C. D. Fillmore, “Braiding geometry and topology to study shapes and data,” Institute of Science and Technology Austria, 2026.","ista":"Fillmore CD. 2026. Braiding geometry and topology to study shapes and data. Institute of Science and Technology Austria.","mla":"Fillmore, Christopher D. <i>Braiding Geometry and Topology to Study Shapes and Data</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21021\">10.15479/AT-ISTA-21021</a>.","short":"C.D. Fillmore, Braiding Geometry and Topology to Study Shapes and Data, Institute of Science and Technology Austria, 2026.","chicago":"Fillmore, Christopher D. “Braiding Geometry and Topology to Study Shapes and Data.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21021\">https://doi.org/10.15479/AT-ISTA-21021</a>.","ama":"Fillmore CD. Braiding geometry and topology to study shapes and data. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21021\">10.15479/AT-ISTA-21021</a>","apa":"Fillmore, C. D. (2026). <i>Braiding geometry and topology to study shapes and data</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21021\">https://doi.org/10.15479/AT-ISTA-21021</a>"},"supervisor":[{"orcid":"0000-0002-9823-6833","id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","first_name":"Herbert","last_name":"Edelsbrunner","full_name":"Edelsbrunner, Herbert"},{"last_name":"Wagner","id":"36690CA2-F248-11E8-B48F-1D18A9856A87","first_name":"Uli","orcid":"0000-0002-1494-0568","full_name":"Wagner, Uli"}],"year":"2026","has_accepted_license":"1","oa_version":"Published Version","oa":1,"file":[{"content_type":"application/pdf","date_updated":"2026-01-30T11:40:09Z","file_size":55954297,"creator":"cfillmor","relation":"main_file","access_level":"open_access","checksum":"4c0889130095c31d4e5088c5b8dfd607","file_id":"21046","file_name":"2025_Fillmore_Christopher_Thesis.pdf","date_created":"2026-01-26T19:44:46Z"},{"date_created":"2026-01-26T19:46:20Z","file_name":"Thesis.zip","file_id":"21047","checksum":"d69afb71d82ab98f856886126ee7303a","access_level":"closed","relation":"source_file","creator":"cfillmor","date_updated":"2026-01-26T19:46:20Z","file_size":166080788,"content_type":"application/x-zip-compressed"}],"file_date_updated":"2026-01-30T11:40:09Z","article_processing_charge":"No","day":"21","date_updated":"2026-04-07T11:42:49Z","publication_status":"published","status":"public","doi":"10.15479/AT-ISTA-21021","ddc":["514","516"],"language":[{"iso":"eng"}],"acknowledgement":"The research presented in this thesis was funded by the DFG Collaborative Research\r\nCenter TRR 109, ‘Discretization in Geometry and Dynamics’.\r\n","OA_place":"publisher","date_created":"2026-01-20T21:38:40Z","_id":"21021","alternative_title":["ISTA Thesis"],"page":"122","date_published":"2026-01-21T00:00:00Z","publisher":"Institute of Science and Technology Austria","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","author":[{"full_name":"Fillmore, Christopher D","last_name":"Fillmore","first_name":"Christopher D","id":"35638A5C-AAC7-11E9-B0BF-5503E6697425"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"department":[{"_id":"GradSch"},{"_id":"HeEd"},{"_id":"UlWa"}],"abstract":[{"text":"This thesis examines how geometry and topology intersect in the representation, transformation, and analysis of complex shapes. It considers how continuous manifolds relate to their discrete analogues, how topological structures evolve in persistence vineyards, and how tools from topological data analysis can illuminate problems in mathematical physics. Central to this exploration is the question of how structure, both geometric and topological, persists or changes under approximation, sampling, or deformation. The work develops new approaches to skeletal and grid-based representations of surfaces, reveals the full expressive capacity of persistence vineyards, and applies topological methods to the longstanding problem of equilibria in electrostatic fields. These threads braid together into a broader understanding of how topology and geometry inform one another across theory, computation, and application.","lang":"eng"}],"type":"dissertation","corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"title":"Braiding geometry and topology to study shapes and data","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"20260"},{"status":"public","relation":"part_of_dissertation","id":"21050"},{"relation":"part_of_dissertation","status":"public","id":"21051"}]}},{"ddc":["520"],"publication_status":"published","status":"public","PlanS_conform":"1","doi":"10.1051/0004-6361/202555596","date_updated":"2026-02-16T07:46:53Z","volume":705,"article_processing_charge":"No","day":"14","file":[{"checksum":"3782e03bc0843438aae8487f6af779c5","access_level":"open_access","relation":"main_file","date_created":"2026-02-16T07:35:03Z","success":1,"file_id":"21224","file_name":"2026_AstronomyAstrophysics_Torralba.pdf","content_type":"application/pdf","creator":"dernst","date_updated":"2026-02-16T07:35:03Z","file_size":2259914}],"file_date_updated":"2026-02-16T07:35:03Z","project":[{"grant_number":"101076224","name":"Young galaxies as tracers and agents of cosmic reionization","_id":"bd9b2118-d553-11ed-ba76-db24564edfea"}],"oa":1,"OA_type":"diamond","oa_version":"Published Version","has_accepted_license":"1","year":"2026","citation":{"ieee":"A. Torralba Torregrosa <i>et al.</i>, “A weak Ly α halo for an extremely bright little red dot. Indications of enshrouded supermassive black hole growth,” <i>Astronomy and Astrophysics</i>, vol. 705. EDP Sciences, 2026.","mla":"Torralba Torregrosa, Alberto, et al. “A Weak Ly α Halo for an Extremely Bright Little Red Dot. Indications of Enshrouded Supermassive Black Hole Growth.” <i>Astronomy and Astrophysics</i>, vol. 705, A147, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202555596\">10.1051/0004-6361/202555596</a>.","short":"A. Torralba Torregrosa, J.J. Matthee, G. Pezzulli, T. Urrutia, M. Gronke, S. Mascia, F. D’Eugenio, C. Di Cesare, A.C. Eilers, J.E. Greene, E. Iani, Y. Ishikawa, R. Mackenzie, R.P. Naidu, B. Navarrete, G. Kotiwale, Astronomy and Astrophysics 705 (2026).","ista":"Torralba Torregrosa A, Matthee JJ, Pezzulli G, Urrutia T, Gronke M, Mascia S, D’Eugenio F, Di Cesare C, Eilers AC, Greene JE, Iani E, Ishikawa Y, Mackenzie R, Naidu RP, Navarrete B, Kotiwale G. 2026. A weak Ly α halo for an extremely bright little red dot. Indications of enshrouded supermassive black hole growth. Astronomy and Astrophysics. 705, A147.","chicago":"Torralba Torregrosa, Alberto, Jorryt J Matthee, Gabriele Pezzulli, Tanya Urrutia, Max Gronke, Sara Mascia, Francesco D’Eugenio, et al. “A Weak Ly α Halo for an Extremely Bright Little Red Dot. Indications of Enshrouded Supermassive Black Hole Growth.” <i>Astronomy and Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202555596\">https://doi.org/10.1051/0004-6361/202555596</a>.","ama":"Torralba Torregrosa A, Matthee JJ, Pezzulli G, et al. A weak Ly α halo for an extremely bright little red dot. Indications of enshrouded supermassive black hole growth. <i>Astronomy and Astrophysics</i>. 2026;705. doi:<a href=\"https://doi.org/10.1051/0004-6361/202555596\">10.1051/0004-6361/202555596</a>","apa":"Torralba Torregrosa, A., Matthee, J. J., Pezzulli, G., Urrutia, T., Gronke, M., Mascia, S., … Kotiwale, G. (2026). A weak Ly α halo for an extremely bright little red dot. Indications of enshrouded supermassive black hole growth. <i>Astronomy and Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202555596\">https://doi.org/10.1051/0004-6361/202555596</a>"},"external_id":{"arxiv":["2505.09542"]},"month":"01","publication":"Astronomy and Astrophysics","title":"A weak Ly α halo for an extremely bright little red dot. Indications of enshrouded supermassive black hole growth","type":"journal_article","corr_author":"1","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"arxiv":1,"abstract":[{"lang":"eng","text":"The abundant population of little red dots (LRDs), compact objects with red UV to optical colors and broad Balmer lines at high redshift, is revealing new insights into the properties of early active galactic nuclei (AGN). Perhaps the most surprising features of this population are the presence of Balmer absorption and ubiquitous strong Balmer breaks. Recent models link these features to an active supermassive black hole (SMBH) cocooned in very dense gas (NH ∼ 1024 cm−2). We present a stringent test of such models using VLT/MUSE observations of A2744-45924, the most luminous LRD known to date (LHα ≈ 1044 erg s−1), located behind the Abell-2744 lensing cluster at z = 4.464 (μ = 1.8). We detect a moderately extended Lyα nebula (h ≈ 5.7 pkpc), spatially offset from the point-like Hα seen by JWST by ≈1.6 pkpc. The Lyα emission is narrow (FWHM = 270 ± 15 km s−1), and faint (Lyα = 0.07Hα) compared to Lyα nebulae typically observed around quasars of similar luminosity. We detect compact N IV]λ1486 emission, spatially aligned with Hα, and a spatial shift in the far-UV continuum matching the Lyα offset. We discuss that Hα and Lyα have distinct physical origins: Hα originates from the AGN, while Lyα is powered by star formation. In the environment of A2744-45924, we identified four extended Lyα halos (Δz < 0.02, Δr < 100 pkpc). Their Lyα luminosities match the expectations based on Hα emission, and show no evidence for radiation from A2744-45924 affecting its surroundings. The lack of strong, compact, and broad Lyα and the absence of a luminous extended halo, suggest that the UV AGN light is obscured by dense gas cloaking the SMBH with a covering factor close to unity."}],"quality_controlled":"1","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"department":[{"_id":"JoMa"},{"_id":"GradSch"}],"author":[{"full_name":"Torralba Torregrosa, Alberto","last_name":"Torralba Torregrosa","id":"018f0249-0e87-11f0-b167-cbce08fbd541","first_name":"Alberto","orcid":"0000-0001-5586-6950"},{"full_name":"Matthee, Jorryt J","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","orcid":"0000-0003-2871-127X","last_name":"Matthee"},{"first_name":"Gabriele","last_name":"Pezzulli","full_name":"Pezzulli, Gabriele"},{"last_name":"Urrutia","first_name":"Tanya","full_name":"Urrutia, Tanya"},{"first_name":"Max","last_name":"Gronke","full_name":"Gronke, Max"},{"id":"edaf889c-c7cd-11ef-ab1b-bb28c431bd29","first_name":"Sara","last_name":"Mascia","full_name":"Mascia, Sara"},{"full_name":"D’Eugenio, Francesco","last_name":"D’Eugenio","first_name":"Francesco"},{"id":"2d002343-372f-11ef-98ec-a164d20427cb","first_name":"Claudia","last_name":"Di Cesare","full_name":"Di Cesare, Claudia"},{"full_name":"Eilers, Anna Christina","last_name":"Eilers","first_name":"Anna Christina"},{"last_name":"Greene","first_name":"Jenny E.","full_name":"Greene, Jenny E."},{"last_name":"Iani","id":"4053390a-6b68-11ef-9828-a3b8adef8d0a","first_name":"Edoardo","orcid":"0000-0001-8386-3546","full_name":"Iani, Edoardo"},{"full_name":"Ishikawa, Yuzo","first_name":"Yuzo","last_name":"Ishikawa"},{"first_name":"Ruari","last_name":"Mackenzie","full_name":"Mackenzie, Ruari"},{"full_name":"Naidu, Rohan P.","last_name":"Naidu","first_name":"Rohan P."},{"id":"aa14a535-50c9-11ef-b52e-e0c373d10148","first_name":"Benjamín","last_name":"Navarrete","full_name":"Navarrete, Benjamín"},{"last_name":"Kotiwale","first_name":"Gauri","id":"1438afc8-1ff6-11ee-9fa6-cd4a75d66875","full_name":"Kotiwale, Gauri"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"EDP Sciences","article_type":"original","date_published":"2026-01-14T00:00:00Z","_id":"21045","intvolume":"       705","article_number":"A147","date_created":"2026-01-25T23:01:41Z","OA_place":"publisher","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"We thank the anonymous referee for constructive and useful comments. We thank Sebastiano Cantalupo for comments on the draft. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programme 114.27M6.001. Funded by the European Union (ERC, AGENTS, 101076224). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Council. Neither the European Union nor the granting authority can be held responsible for them. We acknowledge funding from JWST program GO-3516. This work is based in part on observations made with the NASA/ESA/CSA James Webb Space Telescope. The data were obtained from the Mikulski Archive for Space Telescopes at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-03127 for JWST. These observations are associated with program #3516. MG thanks the Max Planck Society for support through the MPRG. FDE acknowledges support by the Science and Technology Facilities Council (STFC), by the ERC through Advanced Grant 695671 “QUENCH”, and by the UKRI Frontier Research grant RISEandFALL. TU acknowledges funding from the ERC-AdG grant SPECMAP-CGM, GA 101020943. GK acknowledges support from the MERAC foundation."},{"article_processing_charge":"No","day":"24","project":[{"grant_number":"665385","_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","name":"International IST Doctoral Program"},{"_id":"8f060199-16d5-11f0-9cad-f3253b266c46","name":"Keratins in epithelial tissue spreading","grant_number":"PAT 5044023"},{"grant_number":"W1250-B20","name":"Nano-Analytics of Cellular Systems","_id":"252C3B08-B435-11E9-9278-68D0E5697425","call_identifier":"FWF"}],"file_date_updated":"2026-03-24T07:21:43Z","file":[{"title":"Cell git repository","content_type":"application/zip","file_size":725916,"date_updated":"2026-03-16T11:51:10Z","creator":"snaik","relation":"main_file","checksum":"5d1fda7e410f24c311fcf6bcf725698f","access_level":"open_access","file_id":"21461","description":"Python3 library written in C++20 to integrate vertex models. Please read the readme at https://github.com/yketa/cells/blob/main/README.md for detailed instructions for installation and usage of the code in this repository. 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Data associated with Keratins coordinate tissue spreading , Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>.","short":"S. Naik, (2026).","mla":"Naik, Suyash. <i>Data Associated with Keratins Coordinate Tissue Spreading </i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>.","chicago":"Naik, Suyash. “Data Associated with Keratins Coordinate Tissue Spreading .” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>.","apa":"Naik, S. (2026). Data associated with Keratins coordinate tissue spreading . Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21137\">https://doi.org/10.15479/AT-ISTA-21137</a>","ama":"Naik S. Data associated with Keratins coordinate tissue spreading . 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21137\">10.15479/AT-ISTA-21137</a>","ieee":"S. Naik, “Data associated with Keratins coordinate tissue spreading .” Institute of Science and Technology Austria, 2026."},"tmp":{"name":"Creative Commons Attribution-ShareAlike 4.0 International Public License (CC BY-SA 4.0)","short":"CC BY-SA (4.0)","image":"/images/cc_by_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-sa/4.0/legalcode"},"department":[{"_id":"GradSch"},{"_id":"CaHe"},{"_id":"EdHa"}],"author":[{"full_name":"Naik, Suyash","first_name":"Suyash","orcid":"0000-0001-8421-5508","id":"2C0B105C-F248-11E8-B48F-1D18A9856A87","last_name":"Naik"}],"title":"Data associated with Keratins coordinate tissue spreading ","contributor":[{"contributor_type":"researcher","last_name":"Keta","first_name":"Yann-Edwin"},{"last_name":"Henkes","first_name":"Silke ","contributor_type":"supervisor"},{"id":"39427864-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-0912-4566","first_name":"Carl-Philipp J","last_name":"Heisenberg","contributor_type":"supervisor"},{"contributor_type":"supervisor","orcid":"0000-0001-6005-1561","id":"3A9DB764-F248-11E8-B48F-1D18A9856A87","first_name":"Edouard B","last_name":"Hannezo"}],"license":"https://creativecommons.org/licenses/by-sa/4.0/","corr_author":"1","type":"research_data","date_published":"2026-03-24T00:00:00Z","_id":"21137","date_created":"2026-02-04T16:38:02Z","OA_place":"repository","acknowledgement":"We thank all members of the Heisenberg, Henkes, and Hannezo groups for their support. We are also grateful to the Imaging and Optics, Scientific Computing, Life Science Support, and Cryo-Electron Microscopy facilities at ISTA for their technical assistance and support. Numerical simulations were performed using the computational resources from Lorentz Institute and the Academic Leiden Interdisciplinary Cluster Environment (ALICE) provided by Leiden University, and from PMMH provided by Sorbonne Université. S.N has received funding from European Union’s Horizon 2020 research and innovation programme (grant agreement No. 665385). This work was supported by the Austrian Science Fund (FWF) under projects PAT5044023 and W1250 awarded to C.-P.H.","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","publisher":"Institute of Science and Technology Austria"},{"year":"2026","supervisor":[{"full_name":"Lampert, Christoph","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","first_name":"Christoph","orcid":"0000-0001-8622-7887","last_name":"Lampert"}],"citation":{"ieee":"J. A. Scott, “Data heterogeneity and personalization in federated learning,” Institute of Science and Technology Austria, 2026.","apa":"Scott, J. A. (2026). <i>Data heterogeneity and personalization in federated learning</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>","ama":"Scott JA. Data heterogeneity and personalization in federated learning. 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>","chicago":"Scott, Jonathan A. “Data Heterogeneity and Personalization in Federated Learning.” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21198\">https://doi.org/10.15479/AT-ISTA-21198</a>.","ista":"Scott JA. 2026. Data heterogeneity and personalization in federated learning. Institute of Science and Technology Austria.","mla":"Scott, Jonathan A. <i>Data Heterogeneity and Personalization in Federated Learning</i>. Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21198\">10.15479/AT-ISTA-21198</a>.","short":"J.A. Scott, Data Heterogeneity and Personalization in Federated Learning, Institute of Science and Technology Austria, 2026."},"has_accepted_license":"1","month":"02","degree_awarded":"PhD","acknowledged_ssus":[{"_id":"ScienComp"}],"date_updated":"2026-04-07T11:46:11Z","publication_status":"published","status":"public","doi":"10.15479/AT-ISTA-21198","ddc":["005"],"oa_version":"Published Version","oa":1,"file_date_updated":"2026-02-27T10:25:41Z","file":[{"date_created":"2026-02-17T11:46:22Z","file_name":"2026_Scott_Jonathan_Thesis_Source.zip","file_id":"21298","access_level":"closed","checksum":"121c1d968bd86f3630aa7e81d5bbbcb0","relation":"source_file","creator":"jscott","date_updated":"2026-02-17T11:46:22Z","file_size":272379252,"content_type":"application/zip"},{"date_created":"2026-02-27T10:25:41Z","success":1,"file_name":"2026_Jonathan_Scott_Thesis.pdf","file_id":"21366","access_level":"open_access","checksum":"6e3e08ba474bbee8511cc8a839ab2077","relation":"main_file","creator":"jscott","date_updated":"2026-02-27T10:25:41Z","file_size":15220298,"content_type":"application/pdf"}],"article_processing_charge":"No","day":"09","publisher":"Institute of Science and Technology Austria","user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","language":[{"iso":"eng"}],"acknowledgement":"This research was funded in part by the Austrian Science Fund (FWF)\r\n[10.55776/COE12]. Furthermore, the candidate acknowledges the support from the Scientific\r\nService Units (SSU) of ISTA through resources provided by Scientific Computing (SciComp).","OA_place":"publisher","date_created":"2026-02-09T14:59:53Z","_id":"21198","alternative_title":["ISTA Thesis"],"page":"158","date_published":"2026-02-09T00:00:00Z","type":"dissertation","corr_author":"1","publication_identifier":{"issn":["2663-337X"]},"title":"Data heterogeneity and personalization in federated learning","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"20819"},{"id":"17411","status":"public","relation":"part_of_dissertation"},{"relation":"part_of_dissertation","status":"public","id":"18120"},{"relation":"part_of_dissertation","status":"public","id":"21207"}]},"author":[{"first_name":"Jonathan A","id":"e499926b-f6e0-11ea-865d-9c63db0031e8","last_name":"Scott","full_name":"Scott, Jonathan A"}],"department":[{"_id":"GradSch"},{"_id":"ChLa"}],"abstract":[{"lang":"eng","text":"In recent years there has been a massive increase in the amount of data generated in a\r\ndecentralized manner. Ever more powerful edge devices, such as smartphones, have become\r\nubiquitous in most societies on earth. Through text typed, photos taken and apps used,\r\nthese devices, which we refer to as clients, generate enormous amounts of high quality and\r\ncomplex data. Moreover, the nature of these devices means the data they generate is often\r\nsensitive and privacy concerns prevent it being gathered and stored in a central location. This\r\npresents a challenge to the modern machine learning paradigm that requires central access\r\nto large amounts of data. Federated learning (FL) has emerged as one of the answers to\r\nthis problem. Rather than bringing the data to the model, FL sends the model to the data.\r\nModel training takes place on device, with periodically synchronized updates, allowing data to\r\nremain locally stored. While this approach offers significant privacy advantages it comes with\r\nits own set of unique challenges. These include: data heterogeneity, the notion that different\r\ndevices generate data in distinct ways which can negatively impact training dynamics; systems\r\nheterogeneity, meaning that different devices may have differing hardware specifications; high\r\ncommunication costs, which are induced by the repeated transferring of models over the\r\nnetwork and low device computational power, which limits the use of larger models on device.\r\nIn this thesis we present a range of methods for federated learning. We focus primarily on\r\nthe challenge of data heterogeneity, though the methods presented are designed to be well\r\nadapted to the other challenges of a federated setting, such as the constraints of limited\r\ncompute and communication overhead. We first present a method for explicitly modeling client\r\ndata heterogeneity. The approach formulates clients as samples from a certain probability\r\ndistribution and infers the parameters of this distribution from the available training clients.\r\nThis learned distribution then represents the heterogeneity present among the clients and can\r\nbe sampled from in order to create new simulated clients that are similar to the real clients we\r\nhave observed so far. Following this we present two methods for directly dealing with data\r\nheterogeneity through personalization. Highly heterogeneous client data distributions can mean\r\nthat learning a single global model becomes suboptimal, and some form of personalization of\r\nmodels to each individual client is required. Our approaches are based around hypernetworks,\r\nwhich we use to generate personalized model parameters without the need for additional\r\ntraining or finetuning. In the first approach we focus on generating full parameterizations of\r\nclient models using learned embeddings of client data and labels, with a hypernetwork located\r\non the central server. In the second approach we address the more challenging scenario where\r\nwe want to generate a personalized model for a client without any label information. The\r\nhypernetwork is trained to generate a low dimensional representation of a client’s personalized\r\nmodel parameters, allowing it to be transferred to and run on the client devices. In our final\r\npresented method, we change our focus and rather than aim to directly address the challenge\r\nof data heterogeneity, we instead ensure we are unaffected by it. This is done in the context\r\nof k-means clustering and we present a method for federated clustering with a focus on added\r\nprivacy guarantees."}]},{"author":[{"last_name":"Gómez-Pascual","first_name":"Alicia","full_name":"Gómez-Pascual, Alicia"},{"last_name":"Glikman","first_name":"Dow M","id":"ab8acda1-91c1-11f0-aad8-f75d3d6424d8","full_name":"Glikman, Dow M"},{"first_name":"Hui Xin","last_name":"Ng","full_name":"Ng, Hui Xin"},{"last_name":"Tomkins","first_name":"James E.","full_name":"Tomkins, James E."},{"last_name":"Lu","first_name":"Lu","full_name":"Lu, Lu"},{"full_name":"Xu, Ying","last_name":"Xu","first_name":"Ying"},{"full_name":"Ashbrook, David G.","last_name":"Ashbrook","first_name":"David G."},{"first_name":"Catherine","last_name":"Kaczorowski","full_name":"Kaczorowski, Catherine"},{"last_name":"Kempermann","first_name":"Gerd","full_name":"Kempermann, Gerd"},{"first_name":"John","last_name":"Killmar","full_name":"Killmar, John"},{"full_name":"Mozhui, Khyobeni","first_name":"Khyobeni","last_name":"Mozhui"},{"full_name":"Ohlenschläger, Oliver","first_name":"Oliver","last_name":"Ohlenschläger"},{"first_name":"Rudolf","last_name":"Aebersold","full_name":"Aebersold, Rudolf"},{"first_name":"Donald K.","last_name":"Ingram","full_name":"Ingram, Donald K."},{"full_name":"Williams, Evan G.","first_name":"Evan G.","last_name":"Williams"},{"full_name":"Jucker, Mathias","first_name":"Mathias","last_name":"Jucker"},{"last_name":"Overall","first_name":"Rupert W.","full_name":"Overall, Rupert W."},{"first_name":"Robert W.","last_name":"Williams","full_name":"Williams, Robert W."},{"first_name":"Dennis E.M.","last_name":"de Bakker","full_name":"de Bakker, Dennis E.M."}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"department":[{"_id":"GradSch"}],"abstract":[{"lang":"eng","text":"In aged humans and mice, hypobranched glycogen aggregates, known as polyglucosan bodies (PGBs), accumulate in hippocampal astrocytes. While PGBs are linked to cognitive decline in neurological diseases, they remain largely unstudied in the context of typical aging. We show that PGBs arise in autophagy-dysregulated astrocytes in the aged hippocampus, with substantial variation among 32 inbred BXD mouse strains. Genetic mapping through quantitative trait locus analysis identified a major locus (Pgb1) that modulates hippocampal PGB burden. Extensive transcriptomic and proteomic datasets were produced for the aged hippocampus of the BXD family to investigate the mechanism by which the Pgb1 locus modulates PGB burden. We identified that Pgb1 contains allelic Smarcal1 and Usp37 variants and influences PGB burden through trans-regulation of mRNA and protein expression levels, including abundance of glycogen-mobilizing factor PYGB. Furthermore, comprehensive phenome-wide association scans, transcriptomic analyses, and direct behavioral testing demonstrated that cognition remains intact despite age-related PGB burden. A record of this paper’s transparent peer review process is included in the supplemental information."}],"quality_controlled":"1","type":"journal_article","publication_identifier":{"issn":["2405-4712"]},"title":"The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus","language":[{"iso":"eng"}],"acknowledgement":"We would like to thank the Summer School Systems Genetics of Neural Ageing for bringing us together and spurring our international collaboration. We would also like to acknowledge the funding for the Summer School 2022 from the e:Med Systems Medicine Program of the BMBF (Bundesministerium für Bildung und Forschung; German Ministry of Education and Research) to R.W.O. In addition, we would like to thank the FLI imaging core facility for their assistance. A.G.-P. is supported by Fundación Séneca, Región de Murcia, Spain (21259/FPI/19). D.E.M.d.B. is financed by a Rubicon scholarship (452021116) from the Dutch Research Council (NWO). This work was also supported by NIH NIA R01AG070913-01 (R.W.W.), R01AG075813-01 (D.G.A.), and R01AG075818 (C.K.). We acknowledge the help of Larry Mobraaten (Jackson Laboratory, Bar Harbor, MN) with the BXD strains and U. Obermüller for the help with the histology. For the purpose of open access, the authors have applied a CC BY public copyright license to all author-accepted manuscripts arising from this submission.","OA_place":"publisher","date_created":"2026-02-16T10:45:10Z","issue":"2","scopus_import":"1","_id":"21234","intvolume":"        17","article_number":"101488","date_published":"2026-02-18T00:00:00Z","pmid":1,"article_type":"original","publisher":"Elsevier","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","OA_type":"hybrid","oa_version":"Published Version","oa":1,"file":[{"date_created":"2026-02-23T10:32:12Z","success":1,"file_id":"21349","file_name":"2026_CellSystems_GomezPascual.pdf","access_level":"open_access","checksum":"920e8edfd3b8b42f5bb6f86d4c66c54d","relation":"main_file","creator":"dernst","date_updated":"2026-02-23T10:32:12Z","file_size":10606778,"content_type":"application/pdf"}],"file_date_updated":"2026-02-23T10:32:12Z","volume":17,"article_processing_charge":"No","day":"18","date_updated":"2026-02-23T10:35:01Z","publication_status":"published","PlanS_conform":"1","status":"public","doi":"10.1016/j.cels.2025.101488","ddc":["570"],"month":"02","publication":"Cell Systems","citation":{"ieee":"A. Gómez-Pascual <i>et al.</i>, “The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus,” <i>Cell Systems</i>, vol. 17, no. 2. Elsevier, 2026.","chicago":"Gómez-Pascual, Alicia, Dow M Glikman, Hui Xin Ng, James E. Tomkins, Lu Lu, Ying Xu, David G. Ashbrook, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen Aggregation in Astrocytes of the Aged Hippocampus.” <i>Cell Systems</i>. Elsevier, 2026. <a href=\"https://doi.org/10.1016/j.cels.2025.101488\">https://doi.org/10.1016/j.cels.2025.101488</a>.","short":"A. Gómez-Pascual, D.M. Glikman, H.X. Ng, J.E. Tomkins, L. Lu, Y. Xu, D.G. Ashbrook, C. Kaczorowski, G. Kempermann, J. Killmar, K. Mozhui, O. Ohlenschläger, R. Aebersold, D.K. Ingram, E.G. Williams, M. Jucker, R.W. Overall, R.W. Williams, D.E.M. de Bakker, Cell Systems 17 (2026).","ista":"Gómez-Pascual A, Glikman DM, Ng HX, Tomkins JE, Lu L, Xu Y, Ashbrook DG, Kaczorowski C, Kempermann G, Killmar J, Mozhui K, Ohlenschläger O, Aebersold R, Ingram DK, Williams EG, Jucker M, Overall RW, Williams RW, de Bakker DEM. 2026. The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. Cell Systems. 17(2), 101488.","mla":"Gómez-Pascual, Alicia, et al. “The Smarcal1-Usp37 Locus Modulates Glycogen Aggregation in Astrocytes of the Aged Hippocampus.” <i>Cell Systems</i>, vol. 17, no. 2, 101488, Elsevier, 2026, doi:<a href=\"https://doi.org/10.1016/j.cels.2025.101488\">10.1016/j.cels.2025.101488</a>.","apa":"Gómez-Pascual, A., Glikman, D. M., Ng, H. X., Tomkins, J. E., Lu, L., Xu, Y., … de Bakker, D. E. M. (2026). The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. <i>Cell Systems</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.cels.2025.101488\">https://doi.org/10.1016/j.cels.2025.101488</a>","ama":"Gómez-Pascual A, Glikman DM, Ng HX, et al. The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus. <i>Cell Systems</i>. 2026;17(2). doi:<a href=\"https://doi.org/10.1016/j.cels.2025.101488\">10.1016/j.cels.2025.101488</a>"},"year":"2026","external_id":{"pmid":["41633365"]},"has_accepted_license":"1"},{"ddc":["520"],"doi":"10.1051/0004-6361/202556432","status":"public","publication_status":"published","PlanS_conform":"1","DOAJ_listed":"1","date_updated":"2026-04-28T12:01:21Z","day":"10","article_processing_charge":"Yes","volume":706,"file_date_updated":"2026-02-23T12:04:37Z","file":[{"date_created":"2026-02-23T12:04:37Z","file_id":"21350","file_name":"2026_AstronomyAstrophysics_Cristea.pdf","success":1,"access_level":"open_access","checksum":"229b688e6e78cab5bb8e2bac366d1575","relation":"main_file","creator":"dernst","file_size":5352853,"date_updated":"2026-02-23T12:04:37Z","content_type":"application/pdf"}],"oa":1,"oa_version":"Published Version","OA_type":"gold","has_accepted_license":"1","year":"2026","citation":{"ieee":"A.-A. Cristea <i>et al.</i>, “A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant,” <i>Astronomy &#38; Astrophysics</i>, vol. 706. EDP Sciences, 2026.","chicago":"Cristea, Andrei-Alexandru, Ilaria Caiazzo, Tim Cunningham, John C. Raymond, Stephane Vennes, Adela Kawka, Aayush A Desai, et al. “A Half Ring of Ionized Circumstellar Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy &#38; Astrophysics</i>. EDP Sciences, 2026. <a href=\"https://doi.org/10.1051/0004-6361/202556432\">https://doi.org/10.1051/0004-6361/202556432</a>.","mla":"Cristea, Andrei-Alexandru, et al. “A Half Ring of Ionized Circumstellar Material Trapped in the Magnetosphere of a White Dwarf Merger Remnant.” <i>Astronomy &#38; Astrophysics</i>, vol. 706, A188, EDP Sciences, 2026, doi:<a href=\"https://doi.org/10.1051/0004-6361/202556432\">10.1051/0004-6361/202556432</a>.","ista":"Cristea A-A, Caiazzo I, Cunningham T, Raymond JC, Vennes S, Kawka A, Desai AA, Miller DR, Hermes JJ, Fuller J, Heyl J, van Roestel J, Burdge KB, Rodriguez AC, Pelisoli I, Gänsicke BT, Szkody P, Kenyon SJ, Vanderbosch Z, Drake A, Ferrario L, Wickramasinghe D, Karambelkar VR, Justham S, Pakmor R, El-Badry K, Prince T, Kulkarni SR, Graham MJ, Masci FJ, Groom SL, Purdum J, Dekany R, Bellm EC. 2026. A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. Astronomy &#38; Astrophysics. 706, A188.","short":"A.-A. Cristea, I. Caiazzo, T. Cunningham, J.C. Raymond, S. Vennes, A. Kawka, A.A. Desai, D.R. Miller, J.J. Hermes, J. Fuller, J. Heyl, J. van Roestel, K.B. Burdge, A.C. Rodriguez, I. Pelisoli, B.T. Gänsicke, P. Szkody, S.J. Kenyon, Z. Vanderbosch, A. Drake, L. Ferrario, D. Wickramasinghe, V.R. Karambelkar, S. Justham, R. Pakmor, K. El-Badry, T. Prince, S.R. Kulkarni, M.J. Graham, F.J. Masci, S.L. Groom, J. Purdum, R. Dekany, E.C. Bellm, Astronomy &#38; Astrophysics 706 (2026).","apa":"Cristea, A.-A., Caiazzo, I., Cunningham, T., Raymond, J. C., Vennes, S., Kawka, A., … Bellm, E. C. (2026). A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. <i>Astronomy &#38; Astrophysics</i>. EDP Sciences. <a href=\"https://doi.org/10.1051/0004-6361/202556432\">https://doi.org/10.1051/0004-6361/202556432</a>","ama":"Cristea A-A, Caiazzo I, Cunningham T, et al. A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant. <i>Astronomy &#38; Astrophysics</i>. 2026;706. doi:<a href=\"https://doi.org/10.1051/0004-6361/202556432\">10.1051/0004-6361/202556432</a>"},"publication":"Astronomy & Astrophysics","month":"02","related_material":{"link":[{"relation":"press_release","description":"News on ISTA website","url":"https://ista.ac.at/en/news/twos-company-new-class-of-star-remnants/"}]},"title":"A half ring of ionized circumstellar material trapped in the magnetosphere of a white dwarf merger remnant","publication_identifier":{"issn":["0004-6361"],"eissn":["1432-0746"]},"corr_author":"1","type":"journal_article","abstract":[{"text":"Many white dwarfs are observed in compact double white dwarf binaries, and through the emission of gravitational waves, a large fraction are destined to merge. The merger remnants that do not explode in a Type Ia supernova are expected to initially be rapidly rotating and highly magnetized. In this work, we present our discovery of the variable white dwarf ZTF J200832.79+444939.67, hereafter ZTF J2008+4449, as a likely merger remnant showing signs of circumstellar material without a stellar or substellar companion. The nature of ZTF J2008+4449 as a merger remnant is supported by its physical properties: it is hot (35 500 ± 300 K) and massive (1.12 ± 0.03 M\r\n                    <jats:sub>⊙</jats:sub>\r\n                    ), rapidly rotating with a period of ≈6.6 minutes, and likely possesses exceptionally strong magnetic fields (∼400−600 MG) at its surface. Remarkably, we detect a significant period derivative of (1.80 ± 0.09)×10\r\n                    <jats:sup>−12</jats:sup>\r\n                    s/s, indicating that the white dwarf is spinning down, and a soft X-ray emission that is inconsistent with photospheric emission. As the presence of a mass-transferring stellar or brown dwarf companion is excluded by infrared photometry, the detected spin-down and X-ray emission could be tell-tale signs of a magnetically driven wind or of interaction with circumstellar material, possibly originating from the fallback of gravitationally bound merger ejecta or from the tidal disruption of a planetary object. We also detect Balmer emission, which requires the presence of ionized hydrogen in the vicinity of the white dwarf, showing Doppler shifts as high as ≈2000 km s\r\n                    <jats:sup>−1</jats:sup>\r\n                    . The unusual variability of the Balmer emission on the spin period of the white dwarf is consistent with the trapping of a half ring of ionized gas in the magnetosphere of the white dwarf.\r\n                  </jats:p>","lang":"eng"}],"quality_controlled":"1","department":[{"_id":"IlCa"},{"_id":"GradSch"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"author":[{"last_name":"Cristea","id":"4d500bea-31f8-11ee-a48d-d4904fb363c7","first_name":"Andrei-Alexandru","full_name":"Cristea, Andrei-Alexandru"},{"full_name":"Caiazzo, Ilaria","last_name":"Caiazzo","orcid":"0000-0002-4770-5388","first_name":"Ilaria","id":"8ae5b6e7-2a03-11ee-914d-b58ed7a3b47d"},{"last_name":"Cunningham","first_name":"Tim","full_name":"Cunningham, Tim"},{"full_name":"Raymond, John C.","last_name":"Raymond","first_name":"John C."},{"full_name":"Vennes, Stephane","last_name":"Vennes","first_name":"Stephane"},{"last_name":"Kawka","first_name":"Adela","full_name":"Kawka, Adela"},{"full_name":"Desai, Aayush A","last_name":"Desai","id":"502cfd30-32c1-11ee-a9a4-d8dad5c6739e","first_name":"Aayush A"},{"full_name":"Miller, David R.","last_name":"Miller","first_name":"David R."},{"full_name":"Hermes, J. J.","last_name":"Hermes","first_name":"J. J."},{"last_name":"Fuller","first_name":"Jim","full_name":"Fuller, Jim"},{"first_name":"Jeremy","last_name":"Heyl","full_name":"Heyl, Jeremy"},{"full_name":"van Roestel, Jan","first_name":"Jan","last_name":"van Roestel"},{"last_name":"Burdge","first_name":"Kevin B.","full_name":"Burdge, Kevin B."},{"first_name":"Antonio C.","last_name":"Rodriguez","full_name":"Rodriguez, Antonio C."},{"full_name":"Pelisoli, Ingrid","first_name":"Ingrid","last_name":"Pelisoli"},{"first_name":"Boris T.","last_name":"Gänsicke","full_name":"Gänsicke, Boris T."},{"last_name":"Szkody","first_name":"Paula","full_name":"Szkody, Paula"},{"full_name":"Kenyon, Scott J.","first_name":"Scott J.","last_name":"Kenyon"},{"first_name":"Zach","last_name":"Vanderbosch","full_name":"Vanderbosch, Zach"},{"first_name":"Andrew","last_name":"Drake","full_name":"Drake, Andrew"},{"full_name":"Ferrario, Lilia","last_name":"Ferrario","first_name":"Lilia"},{"first_name":"Dayal","last_name":"Wickramasinghe","full_name":"Wickramasinghe, Dayal"},{"last_name":"Karambelkar","first_name":"Viraj R.","full_name":"Karambelkar, Viraj R."},{"last_name":"Justham","first_name":"Stephen","full_name":"Justham, Stephen"},{"first_name":"Ruediger","last_name":"Pakmor","full_name":"Pakmor, Ruediger"},{"full_name":"El-Badry, Kareem","last_name":"El-Badry","first_name":"Kareem"},{"first_name":"Thomas","last_name":"Prince","full_name":"Prince, Thomas"},{"last_name":"Kulkarni","first_name":"S. R.","full_name":"Kulkarni, S. R."},{"full_name":"Graham, Matthew J.","last_name":"Graham","first_name":"Matthew J."},{"first_name":"Frank J.","last_name":"Masci","full_name":"Masci, Frank J."},{"full_name":"Groom, Steven L.","first_name":"Steven L.","last_name":"Groom"},{"last_name":"Purdum","first_name":"Josiah","full_name":"Purdum, Josiah"},{"first_name":"Richard","last_name":"Dekany","full_name":"Dekany, Richard"},{"full_name":"Bellm, Eric C.","last_name":"Bellm","first_name":"Eric C."}],"user_id":"ba8df636-2132-11f1-aed0-ed93e2281fdd","article_type":"original","publisher":"EDP Sciences","date_published":"2026-02-10T00:00:00Z","article_number":"A188","intvolume":"       706","_id":"21274","date_created":"2026-02-17T08:12:05Z","OA_place":"publisher","acknowledgement":"We thank Lynne Hillenbrand and Soumyadeep Bhattacharjee for helpful discussions, and Kishalay De for his help with the WIRC\r\nreduction pipeline. IC was supported by NASA through grants from the Space\r\nTelescope Science Institute, under NASA contracts NASA.22K1813, NAS5-\r\n26555 and NAS5-03127. TC was supported by NASA through the NASA Hubble\r\nFellowship grant HST-HF2-51527.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research\r\nin Astronomy, Inc., for NASA, under contract NAS5-26555. This project has\r\nreceived funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant agreement No. 101020057). This work was based on observations obtained with the\r\nSamuel Oschin Telescope 48-inch and the 60-inch Telescope at the Palomar\r\nObservatory as part of the Zwicky Transient Facility project. ZTF is supported\r\nby the National Science Foundation under Grants No. AST-1440341, AST2034437, and currently Award #2407588. ZTF receives additional funding from\r\nthe ZTF partnership. Current members include Caltech, USA; Caltech/IPAC,\r\nUSA; University of Maryland, USA; University of California, Berkeley, USA;\r\nUniversity of Wisconsin at Milwaukee, USA; Cornell University, USA; Drexel\r\nUniversity, USA; University of North Carolina at Chapel Hill, USA; Institute\r\nof Science and Technology, Austria; National Central University, Taiwan, and\r\nOKC, University of Stockholm, Sweden. Operations are conducted by Caltech’s\r\nOptical Observatory (COO), Caltech/IPAC, and the University of Washington at\r\nSeattle, USA. This work has made use of data from the European Space Agency\r\n(ESA) mission Gaia (https://www.cosmos.esa.int/gaia), processed by\r\nthe Gaia Data Processing and Analysis Consortium (DPAC, https://www.\r\ncosmos.esa.int/web/gaia/dpac/consortium). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. The Pan-STARRS1 Surveys (PS1)\r\nand the PS1 public science archive have been made possible through contributions by the Institute for Astronomy, the University of Hawaii, the PanSTARRS Project Office, the Max-Planck Society and its participating institutes, the Max Planck Institute for Astronomy, Heidelberg and the Max Planck\r\nInstitute for Extraterrestrial Physics, Garching, The Johns Hopkins University,\r\nDurham University, the University of Edinburgh, the Queen’s University Belfast,\r\nthe Harvard-Smithsonian Center for Astrophysics, the Las Cumbres Observatory Global Telescope Network Incorporated, the National Central University of Taiwan, the Space Telescope Science Institute, the National Aeronautics and Space Administration under Grant No. NNX08AR22G issued through\r\nthe Planetary Science Division of the NASA Science Mission Directorate, the\r\nNational Science Foundation Grant No. AST–1238877, the University of Maryland, Eotvos Lorand University (ELTE), the Los Alamos National Laboratory,\r\nand the Gordon and Betty Moore Foundation. This work made use of Astropy\r\n(http://www.astropy.org): a community-developed core Python package\r\nand an ecosystem of tools and resources for astronomy (Astropy Collaboration\r\n2013, 2018, 2022).","language":[{"iso":"eng"}]},{"abstract":[{"lang":"eng","text":"The advantageous characteristics attributed to the 19F nucleus have made it a popular target for NMR once again in recent years. Aside from solution NMR, an increasing number of studies have been conducted applying solid-state magic-angle-spinning NMR to fluorine-labeled samples. Here, the high chemical shift anisotropy and strong dipolar couplings can be utilized to get structural insights into proteins and measure long distances. Despite increasing popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR often suffers from slow longitudinal T1 relaxation and therefore long recycle delays. In this work, we expand paramagnetic doping, an approach commonly used to reduce proton T1 relaxation times, to 19F-labeled biological samples. We study the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F and 13C T1 and T2 relaxation in a [5-19F13C]-tryptophan-labeled protein via 19F-detected MAS NMR experiments. The observed paramagnetic relaxation enhancement substantially reduces measurement times of 19F MAS NMR experiments without compromising resolution. Additionally, we report the chemical-shift assignments of all four fluorotryptophan signals in the 12 × 39 kDa large protein using a mutagenesis approach."}],"author":[{"orcid":"0000-0002-6401-5151","id":"36336939-eb97-11eb-a6c2-c83f1214ca79","first_name":"Lea Marie","last_name":"Becker","full_name":"Becker, Lea Marie"},{"full_name":"Schanda, Paul","last_name":"Schanda","first_name":"Paul","id":"7B541462-FAF6-11E9-A490-E8DFE5697425","orcid":"0000-0002-9350-7606"}],"department":[{"_id":"GradSch"},{"_id":"PaSc"}],"tmp":{"short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode"},"title":"Research data for \"Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants\"","license":"https://creativecommons.org/licenses/by-nc/4.0/","type":"research_data","corr_author":"1","contributor":[{"contributor_type":"researcher","last_name":"Toscano","id":"334a5e40-8747-11f0-b671-ba1f5154b4b4","first_name":"Giorgia"},{"first_name":"Anna","id":"9fb2a840-89e1-11ee-a8b7-cc5c7ba62471","last_name":"Kapitonova","contributor_type":"researcher"},{"id":"a3089acd-6806-11ee-bacc-f0c7d500ad20","first_name":"Rajkumar","last_name":"Singh","contributor_type":"researcher"},{"contributor_type":"researcher","id":"bb74f472-ae54-11eb-9835-bc9c22fb1183","first_name":"Undina","last_name":"Guillerm"},{"contributor_type":"researcher","first_name":"Roman","last_name":"Lichtenecker"}],"_id":"21284","date_published":"2026-02-18T00:00:00Z","acknowledgement":"We thank Ben P. Tatman for insightful discussions. This research was supported by the Scientific Service Units (SSU) of Institute of Science and Technology Austria (ISTA) through resources provided by the Nuclear Magnetic Resonance Facility and the Lab Support Facility.","date_created":"2026-02-17T10:17:14Z","OA_place":"repository","publisher":"Institute of Science and Technology Austria","user_id":"68b8ca59-c5b3-11ee-8790-cd641c68093d","file_date_updated":"2026-02-17T10:11:14Z","file":[{"date_updated":"2026-02-17T10:11:14Z","file_size":36996027,"creator":"lbecker","content_type":"application/zip","success":1,"file_id":"21285","file_name":"Research_data.zip","date_created":"2026-02-17T10:11:14Z","relation":"main_file","checksum":"2d3105f26be578073b88ee1f2ea0bdb1","access_level":"open_access"},{"content_type":"text/plain","creator":"lbecker","date_updated":"2026-02-17T10:11:14Z","file_size":1993,"checksum":"e24aebcdb8856cb181cbaa02de020ddb","access_level":"open_access","relation":"table_of_contents","date_created":"2026-02-17T10:11:14Z","file_id":"21286","file_name":"README.txt"}],"day":"18","article_processing_charge":"No","oa_version":"Published Version","OA_type":"free access","oa":1,"doi":"10.15479/AT-ISTA-21284","status":"public","ddc":["541"],"date_updated":"2026-06-10T09:28:41Z","month":"2","acknowledged_ssus":[{"_id":"NMR"},{"_id":"LifeSc"}],"has_accepted_license":"1","citation":{"mla":"Becker, Lea Marie, and Paul Schanda. <i>Research Data for “Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.”</i> Institute of Science and Technology Austria, 2026, doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>.","ista":"Becker LM, Schanda P. 2026. Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>.","short":"L.M. Becker, P. Schanda, (2026).","chicago":"Becker, Lea Marie, and Paul Schanda. “Research Data for ‘Accelerated 19F Biomolecular Magic-Angle Spinning NMR with Paramagnetic Dopants.’” Institute of Science and Technology Austria, 2026. <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">https://doi.org/10.15479/AT-ISTA-21284</a>.","apa":"Becker, L. M., &#38; Schanda, P. (2026). Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT-ISTA-21284\">https://doi.org/10.15479/AT-ISTA-21284</a>","ama":"Becker LM, Schanda P. Research data for “Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.” 2026. doi:<a href=\"https://doi.org/10.15479/AT-ISTA-21284\">10.15479/AT-ISTA-21284</a>","ieee":"L. M. Becker and P. Schanda, “Research data for ‘Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants.’” Institute of Science and Technology Austria, 2026."},"year":"2026"},{"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Springer Nature","article_type":"original","date_created":"2026-02-17T11:38:41Z","OA_place":"publisher","scopus_import":"1","language":[{"iso":"eng"}],"acknowledgement":"The work was supported by the Simons Foundation (grant number 662960, to B.H.). Open access funding provided by Institute of Science and Technology (IST Austria).","date_published":"2026-02-17T00:00:00Z","_id":"21295","corr_author":"1","type":"journal_article","publication_identifier":{"issn":["1745-2473"],"eissn":["1745-2481"]},"arxiv":1,"title":"Discontinuous transition to shear flow turbulence","department":[{"_id":"GradSch"},{"_id":"BjHo"}],"tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"author":[{"full_name":"Yang, Bowen","id":"71b6ff4b-15b2-11ec-abd3-aef6b028cf7e","orcid":"0000-0002-4843-6853","first_name":"Bowen","last_name":"Yang"},{"id":"3677B57C-F248-11E8-B48F-1D18A9856A87","first_name":"Yi","last_name":"Zhuang","full_name":"Zhuang, Yi"},{"full_name":"Yalniz, Gökhan","last_name":"Yalniz","id":"66E74FA2-D8BF-11E9-8249-8DE2E5697425","orcid":"0000-0002-8490-9312","first_name":"Gökhan"},{"full_name":"Vasudevan, Mukund","last_name":"Vasudevan","id":"3C5A959A-F248-11E8-B48F-1D18A9856A87","first_name":"Mukund"},{"full_name":"Marensi, Elena","last_name":"Marensi","orcid":"0000-0001-7173-4923","first_name":"Elena","id":"0BE7553A-1004-11EA-B805-18983DDC885E"},{"last_name":"Hof","id":"3A374330-F248-11E8-B48F-1D18A9856A87","first_name":"Björn","orcid":"0000-0003-2057-2754","full_name":"Hof, Björn"}],"abstract":[{"lang":"eng","text":"Depending on the type of flow, the transition to turbulence can take one of two forms: either turbulence arises from a sequence of instabilities or from the spatial proliferation of transiently chaotic domains, a process analogous to directed percolation. The former scenario is commonly referred to as a supercritical transition and frequently encountered in flows destabilized by body forces, whereas the latter subcritical transition is common in shear flows. Both cases are inherently continuous in a sense that the transformation from ordered laminar to fully turbulent fluid motion is only accomplished gradually with flow speed. Here we show that these established transition types do not account for the more general setting of shear flows subject to body forces. The combination of the two continuous scenarios leads to the attenuation of spatial coupling; with increasing forcing amplitude, the transition becomes increasingly sharp and eventually discontinuous. We argue that the suppression of laminar–turbulent coexistence and the approach towards a discontinuous phase transition potentially apply to a broad range of situations including flows subject to, for example, buoyancy, centrifugal or electromagnetic forces."}],"quality_controlled":"1","year":"2026","citation":{"apa":"Yang, B., Zhuang, Y., Yalniz, G., Vasudevan, M., Marensi, E., &#38; Hof, B. (2026). Discontinuous transition to shear flow turbulence. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-025-03166-3\">https://doi.org/10.1038/s41567-025-03166-3</a>","ama":"Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. Discontinuous transition to shear flow turbulence. <i>Nature Physics</i>. 2026. doi:<a href=\"https://doi.org/10.1038/s41567-025-03166-3\">10.1038/s41567-025-03166-3</a>","chicago":"Yang, Bowen, Yi Zhuang, Gökhan Yalniz, Mukund Vasudevan, Elena Marensi, and Björn Hof. “Discontinuous Transition to Shear Flow Turbulence.” <i>Nature Physics</i>. Springer Nature, 2026. <a href=\"https://doi.org/10.1038/s41567-025-03166-3\">https://doi.org/10.1038/s41567-025-03166-3</a>.","mla":"Yang, Bowen, et al. “Discontinuous Transition to Shear Flow Turbulence.” <i>Nature Physics</i>, Springer Nature, 2026, doi:<a href=\"https://doi.org/10.1038/s41567-025-03166-3\">10.1038/s41567-025-03166-3</a>.","ista":"Yang B, Zhuang Y, Yalniz G, Vasudevan M, Marensi E, Hof B. 2026. Discontinuous transition to shear flow turbulence. Nature Physics.","short":"B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, B. Hof, Nature Physics (2026).","ieee":"B. Yang, Y. Zhuang, G. Yalniz, M. Vasudevan, E. Marensi, and B. Hof, “Discontinuous transition to shear flow turbulence,” <i>Nature Physics</i>. Springer Nature, 2026."},"external_id":{"arxiv":["2311.11474"]},"has_accepted_license":"1","month":"02","publication":"Nature Physics","date_updated":"2026-02-23T11:36:46Z","ddc":["532"],"PlanS_conform":"1","publication_status":"epub_ahead","status":"public","doi":"10.1038/s41567-025-03166-3","OA_type":"hybrid","oa_version":"Published Version","day":"17","article_processing_charge":"Yes (via OA deal)","project":[{"grant_number":"662960","name":"Revisiting the Turbulence Problem Using Statistical Mechanics","_id":"238598C6-32DE-11EA-91FC-C7463DDC885E"}]}]