---
OA_type: closed access
_id: '21762'
abstract:
- lang: eng
  text: Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular
    organization. The plasmid-encoded ParMRC system forms actin-like filaments that
    segregate low–copy number plasmids. In multicellular cyanobacteria such as Anabaena
    sp., we found that a chromosomally encoded ParMR system has evolved into a cytoskeletal
    system named CorMR with a function in cell shape control rather than DNA segregation.
    Live-cell imaging, in vitro reconstitution, and cryo–electron microscopy revealed
    that CorM formed dynamically unstable, antiparallel double-stranded filaments
    that were recruited to the membrane by CorR through an amphipathic helix conserved
    in multicellular cyanobacteria. CorMR filaments were regulated by MinC, which
    excluded them from the poles and division plane. Comparative genomics indicated
    that the repurposing of ParMR and Min systems coevolved with cyanobacterial multicellularity,
    highlighting the evolutionary plasticity of cytoskeletal systems in bacteria.
acknowledged_ssus:
- _id: Bio
- _id: ScienComp
- _id: EM-Fac
- _id: LifeSc
acknowledgement: "We thank all members of the Loose lab at ISTA for helpful discussions;
  M. Kojic for critical reading of the manuscript; A. Herrero (Sevilla University)
  for sharing her extensive BACTH plasmid library and other plasmids, as well as cyanobacterial
  strains; T. Dagan and F. Nies (both Kiel University) for sharing cyanobacterial
  strains and plasmids and for valuable discussions; N. Sapay and A. Michon for providing
  the Amphipaseek code, which enabled us to perform our large-scale amphipathic helix
  screen of cyanobacterial CorR proteins; V.-V. Hodirnau for support in cryo-ET data
  collection; and J. Hansen for advice about cryo-EM data processing.\r\nThis work
  was supported by the Scientific Service Units (SSU) of ISTA through resources provided
  by the Imaging & Optics Facility (IOF), the Scientific Computing (SciComp), the
  Electron Microscopy Facility (EMF), and the Lab Support Facility (LSF). This work
  was funded by the European Union’s Horizon 2020 research and innovation program
  (Marie Skłodowska-Curie grant 101034413 to B.L.S.); the European Research Council
  (ERC) of the European Union (grant ActinID 101076260 to F.K.M.S.); the Swiss National
  Science Foundation (starting grant TMSGI3_226208 to G.L.W.); and the Jean-Jacques
  et Letitia Lopez-Loreta Foundation (G.L.W.)."
article_number: eaea6343
article_processing_charge: No
article_type: original
author:
- first_name: Benjamin L
  full_name: Springstein, Benjamin L
  id: b4eb62ef-ac72-11ed-9503-ed3b4d66c083
  last_name: Springstein
  orcid: 0000-0002-3461-5391
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
  orcid: 0000-0003-2311-2112
- first_name: Daniela
  full_name: Megrian, Daniela
  last_name: Megrian
- first_name: Roman
  full_name: Hajdu, Roman
  id: ffab949d-133f-11ed-8f02-94de21ace503
  last_name: Hajdu
- first_name: Dustin M.
  full_name: Hanke, Dustin M.
  last_name: Hanke
- first_name: Bettina
  full_name: Zens, Bettina
  id: 45FD126C-F248-11E8-B48F-1D18A9856A87
  last_name: Zens
  orcid: 0000-0002-9561-1239
- first_name: Gregor L.
  full_name: Weiss, Gregor L.
  last_name: Weiss
- first_name: Florian Km
  full_name: Schur, Florian Km
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
citation:
  ama: Springstein BL, Javoor M, Megrian D, et al. Repurposing of a DNA segregation
    machinery into a cytoskeletal system controlling cell shape. <i>Science</i>. 2026;392(6795).
    doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>
  apa: Springstein, B. L., Javoor, M., Megrian, D., Hajdu, R., Hanke, D. M., Zens,
    B., … Loose, M. (2026). Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. <i>Science</i>. AAAS. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>
  chicago: Springstein, Benjamin L, Manjunath Javoor, Daniela Megrian, Roman Hajdu,
    Dustin M. Hanke, Bettina Zens, Gregor L. Weiss, Florian KM Schur, and Martin Loose.
    “Repurposing of a DNA Segregation Machinery into a Cytoskeletal System Controlling
    Cell Shape.” <i>Science</i>. AAAS, 2026. <a href="https://doi.org/10.1126/science.aea6343">https://doi.org/10.1126/science.aea6343</a>.
  ieee: B. L. Springstein <i>et al.</i>, “Repurposing of a DNA segregation machinery
    into a cytoskeletal system controlling cell shape,” <i>Science</i>, vol. 392,
    no. 6795. AAAS, 2026.
  ista: Springstein BL, Javoor M, Megrian D, Hajdu R, Hanke DM, Zens B, Weiss GL,
    Schur FK, Loose M. 2026. Repurposing of a DNA segregation machinery into a cytoskeletal
    system controlling cell shape. Science. 392(6795), eaea6343.
  mla: Springstein, Benjamin L., et al. “Repurposing of a DNA Segregation Machinery
    into a Cytoskeletal System Controlling Cell Shape.” <i>Science</i>, vol. 392,
    no. 6795, eaea6343, AAAS, 2026, doi:<a href="https://doi.org/10.1126/science.aea6343">10.1126/science.aea6343</a>.
  short: B.L. Springstein, M. Javoor, D. Megrian, R. Hajdu, D.M. Hanke, B. Zens, G.L.
    Weiss, F.K. Schur, M. Loose, Science 392 (2026).
corr_author: '1'
date_created: 2026-04-26T22:01:46Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-04-28T13:29:05Z
day: '16'
department:
- _id: MaLo
- _id: FlSc
- _id: GradSch
- _id: EM-Fac
doi: 10.1126/science.aea6343
ec_funded: 1
external_id:
  pmid:
  - '41990175'
intvolume: '       392'
issue: '6795'
language:
- iso: eng
month: '04'
oa_version: None
pmid: 1
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
- _id: bd980d18-d553-11ed-ba76-ceaa645c97eb
  grant_number: '101076260'
  name: A molecular atlas of Actin filament IDentities in the cell motility machinery
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Repurposing of a DNA segregation machinery into a cytoskeletal system controlling
  cell shape
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21763'
abstract:
- lang: eng
  text: Reactive oxygen species (ROS) have been implicated in multiple signaling processes
    in plants, but the underlying mechanisms and roles remain enigmatic. In this study,
    we developed a method of live imaging of apoplastic ROS at the root surface. Distinct
    signals, including auxin, extracellular adenosine triphosphate, and rapid alkalinization
    factor 1 peptide, induce cytosolic calcium transients and apoplastic ROS bursts.
    Genetic and optogenetic manipulations of Arabidopsis identified calcium transients
    as necessary and sufficient for ROS bursts through activation of reduced nicotinamide
    adenine dinucleotide phosphate (NADPH) oxidases RBOHC and RBOHF. Apoplastic ROS
    bursts are not required, but they do limit gravity-induced root bending. Root
    bending is sensed by the stretch-activated calcium channel MCA1, leading to NADPH
    oxidase activation. The resulting ROS production stiffens cell walls to facilitate
    soil penetration. Apoplastic ROS thus provides a means to balance tissue flexibility
    and stiffness to navigate soil.
acknowledged_ssus:
- _id: LifeSc
- _id: Bio
acknowledgement: "We gratefully acknowledge the Lab Support Facility (LSF) and the
  Imaging and Optics Facility (IOF) (both of ISTA) and the Hounsfield CT Facility
  (University of Nottingham) for support with imaging and the Growth Facility (IPMB)
  for plant cultivation. We thank M. Fendrych and his team for help with the microfluidics
  upgrades and J. Atkinson at the University of Nottingham MakerSpace for 3D printing
  of Arabidopsis mini-soil columns.\r\nThis project received funding from the European
  Research Council (ERC; 101142681 CYNIPS) and the Austrian Science Fund (FWF; P 37051-B).
  I.K. was cofunded by the European Union, Horizon Europe, project MOLIPEC, ID 101087030
  and CSF project 25-16449S. L.V. and B.K.P. acknowledge funding from UK Research
  and Innovation (UKRI) Frontiers Research (EP/Y036697/1). M.J.B. acknowledges funding
  from ERC SYNERGY (grant 101118769 HYDROSENSING). The study was partially supported
  by the Université Paris Cité, Idex ANR-18-IDEX-0001, funded by the French Government
  through its “Investments for the Future” program and also by the projects “Mecha-Nuc”
  ANR-20-CE13-0025-03 and “scEm-bryoMech” ANR-21-CE13-0046. P.D. acknowledges support
  by Human Frontier Science Program Organization grant 2022-RG107. P.V. acknowledges
  support provided by “Programme blanc” of the Graduate School BIOSPHERA, Université
  Paris-Saclay. Phytohormonal analysis was performed using the service laboratory
  funded by Toward Next GENeration Crops, reg. no. CZ.02.01.01/00/22_008/0004581 of
  the European Regional Development Fund (ERDF) program Johannes Amos Comenius. This
  research was funded in whole or in part by the Austrian Science Fund (P 37051-B)
  and UK Research and Innovation (EP/Y036697/1), cOAlition S organizations, and by
  the European Research Council (101142681 CYNIPS, 101118769 HYDROSENSING); as required,
  the author will make the Author Accepted Manuscript (AAM) version available under
  a CC BY public copyright license."
article_processing_charge: No
article_type: original
author:
- first_name: Ivan
  full_name: Kulich, Ivan
  id: 57a1567c-8314-11eb-9063-c9ddc3451a54
  last_name: Kulich
- first_name: Dmitrii
  full_name: Vladimirtsev, Dmitrii
  id: 60466724-5355-11ee-ae5a-fa55e8f99c3d
  last_name: Vladimirtsev
- first_name: Marek
  full_name: Randuch, Marek
  id: 6ac4636d-15b2-11ec-abd3-fb8df79972ae
  last_name: Randuch
- first_name: Shiqiang
  full_name: Gao, Shiqiang
  last_name: Gao
- first_name: Matteo
  full_name: Citterico, Matteo
  last_name: Citterico
- first_name: Kai R.
  full_name: Konrad, Kai R.
  last_name: Konrad
- first_name: Georg
  full_name: Nagel, Georg
  last_name: Nagel
- first_name: Michael
  full_name: Wrzaczek, Michael
  last_name: Wrzaczek
- first_name: Léa
  full_name: Cascaro, Léa
  last_name: Cascaro
- first_name: Pauline
  full_name: Vinet, Pauline
  last_name: Vinet
- first_name: Pauline
  full_name: Durand, Pauline
  last_name: Durand
- first_name: Atef
  full_name: Asnacios, Atef
  last_name: Asnacios
- first_name: Lokesh
  full_name: Verma, Lokesh
  last_name: Verma
- first_name: Malcolm J.
  full_name: Bennett, Malcolm J.
  last_name: Bennett
- first_name: Bipin K.
  full_name: Pandey, Bipin K.
  last_name: Pandey
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Kulich I, Vladimirtsev D, Randuch M, et al. Calcium-triggered apoplastic ROS
    bursts balance gravity and mechanical signals for soil navigation. <i>Science</i>.
    2026;392(6795):296-300. doi:<a href="https://doi.org/10.1126/science.adu8197">10.1126/science.adu8197</a>
  apa: Kulich, I., Vladimirtsev, D., Randuch, M., Gao, S., Citterico, M., Konrad,
    K. R., … Friml, J. (2026). Calcium-triggered apoplastic ROS bursts balance gravity
    and mechanical signals for soil navigation. <i>Science</i>. AAAS. <a href="https://doi.org/10.1126/science.adu8197">https://doi.org/10.1126/science.adu8197</a>
  chicago: Kulich, Ivan, Dmitrii Vladimirtsev, Marek Randuch, Shiqiang Gao, Matteo
    Citterico, Kai R. Konrad, Georg Nagel, et al. “Calcium-Triggered Apoplastic ROS
    Bursts Balance Gravity and Mechanical Signals for Soil Navigation.” <i>Science</i>.
    AAAS, 2026. <a href="https://doi.org/10.1126/science.adu8197">https://doi.org/10.1126/science.adu8197</a>.
  ieee: I. Kulich <i>et al.</i>, “Calcium-triggered apoplastic ROS bursts balance
    gravity and mechanical signals for soil navigation,” <i>Science</i>, vol. 392,
    no. 6795. AAAS, pp. 296–300, 2026.
  ista: Kulich I, Vladimirtsev D, Randuch M, Gao S, Citterico M, Konrad KR, Nagel
    G, Wrzaczek M, Cascaro L, Vinet P, Durand P, Asnacios A, Verma L, Bennett MJ,
    Pandey BK, Friml J. 2026. Calcium-triggered apoplastic ROS bursts balance gravity
    and mechanical signals for soil navigation. Science. 392(6795), 296–300.
  mla: Kulich, Ivan, et al. “Calcium-Triggered Apoplastic ROS Bursts Balance Gravity
    and Mechanical Signals for Soil Navigation.” <i>Science</i>, vol. 392, no. 6795,
    AAAS, 2026, pp. 296–300, doi:<a href="https://doi.org/10.1126/science.adu8197">10.1126/science.adu8197</a>.
  short: I. Kulich, D. Vladimirtsev, M. Randuch, S. Gao, M. Citterico, K.R. Konrad,
    G. Nagel, M. Wrzaczek, L. Cascaro, P. Vinet, P. Durand, A. Asnacios, L. Verma,
    M.J. Bennett, B.K. Pandey, J. Friml, Science 392 (2026) 296–300.
corr_author: '1'
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:20:07Z
day: '16'
ddc:
- '580'
department:
- _id: JiFr
- _id: GradSch
doi: 10.1126/science.adu8197
external_id:
  pmid:
  - '41990180'
file:
- access_level: open_access
  checksum: eb5b29247832ecdc53c8146da0509bbe
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T05:54:43Z
  date_updated: 2026-05-07T05:54:43Z
  file_id: '21832'
  file_name: 2026_Science_Kulich_accepted.pdf
  file_size: 6150733
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T05:54:43Z
has_accepted_license: '1'
intvolume: '       392'
issue: '6795'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Accepted Version
page: 296-300
pmid: 1
project:
- _id: 8f347782-16d5-11f0-9cad-8c19706ee739
  grant_number: '101142681'
  name: Cyclic nucleotides as second messengers in plants
- _id: 7bcece63-9f16-11ee-852c-ae94e099eeb6
  grant_number: P37051
  name: Guanylate cyclase activity of TIR1/AFBs auxin receptors
publication: Science
publication_identifier:
  eissn:
  - 1095-9203
  issn:
  - 0036-8075
publication_status: published
publisher: AAAS
quality_controlled: '1'
scopus_import: '1'
status: public
title: Calcium-triggered apoplastic ROS bursts balance gravity and mechanical signals
  for soil navigation
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 392
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21764'
abstract:
- lang: eng
  text: "Colloidal fluids can exhibit complex phase behavior and determining phase
    diagrams via experiments or computer simulations can be laborious. We demonstrate
    that the dispersion relation ω(k), obtained from dynamical density functional
    theory for the uniform density system, is a highly versatile tool for predicting
    where in the phase diagram complex crystals form. The sign of ω(k) determines
    whether density modes with wave number k grow or decay over time. We demonstrate
    the predictive power by investigating the complex phase behavior of particles
    interacting via core-shoulder pair potentials. With complementary Monte Carlo
    simulations, we show that regions of the phase diagram where ωðkÞ has one or several
    unstable (growing) wave numbers are also where crystalline phases occur. Going
    further, by tuning these\r\nunstable wave numbers via the interaction-potential
    and state-point parameters, we design systems with quasicrystals in the phase
    diagram. We identify a system with a certain shoulder range exhibiting at least
    ten different phases. Our general approach accelerates considerably the mapping
    of complex phase diagrams, crucial for the design of new materials."
acknowledgement: "The authors thank Ms. Katrin Muck for her guidance related to the
  use of HPC. The MC\r\ncomputer simulation results presented here were enabled via
  a generous share of CPU time, offered by the Vienna Scientific Cluster (VSC) under
  Project No. 71263. A. J. A. gratefully acknowledges support from the EPSRC under
  Grant No. EP/P015689/1. This research was funded in part by the Austrian Science
  Fund (FWF) [Grant DOI: 10.55776/PIN8759524], gratefully acknowledged by G. K ."
article_number: '148203'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Wassermair, Michael
  id: 23d132c4-4e98-11ef-b275-9e8d4cd8c917
  last_name: Wassermair
  orcid: 0009-0003-6339-4051
- first_name: Gerhard
  full_name: Kahl, Gerhard
  last_name: Kahl
- first_name: Roland
  full_name: Roth, Roland
  last_name: Roth
- first_name: Andrew J.
  full_name: Archer, Andrew J.
  last_name: Archer
citation:
  ama: Wassermair M, Kahl G, Roth R, Archer AJ. Navigating complex phase diagrams
    in soft matter systems. <i>Physical Review Letters</i>. 2026;136(14). doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>
  apa: Wassermair, M., Kahl, G., Roth, R., &#38; Archer, A. J. (2026). Navigating
    complex phase diagrams in soft matter systems. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>
  chicago: Wassermair, Michael, Gerhard Kahl, Roland Roth, and Andrew J. Archer. “Navigating
    Complex Phase Diagrams in Soft Matter Systems.” <i>Physical Review Letters</i>.
    American Physical Society, 2026. <a href="https://doi.org/10.1103/nbvt-fgjy">https://doi.org/10.1103/nbvt-fgjy</a>.
  ieee: M. Wassermair, G. Kahl, R. Roth, and A. J. Archer, “Navigating complex phase
    diagrams in soft matter systems,” <i>Physical Review Letters</i>, vol. 136, no.
    14. American Physical Society, 2026.
  ista: Wassermair M, Kahl G, Roth R, Archer AJ. 2026. Navigating complex phase diagrams
    in soft matter systems. Physical Review Letters. 136(14), 148203.
  mla: Wassermair, Michael, et al. “Navigating Complex Phase Diagrams in Soft Matter
    Systems.” <i>Physical Review Letters</i>, vol. 136, no. 14, 148203, American Physical
    Society, 2026, doi:<a href="https://doi.org/10.1103/nbvt-fgjy">10.1103/nbvt-fgjy</a>.
  short: M. Wassermair, G. Kahl, R. Roth, A.J. Archer, Physical Review Letters 136
    (2026).
date_created: 2026-04-26T22:01:47Z
date_published: 2026-04-10T00:00:00Z
date_updated: 2026-04-28T07:03:48Z
day: '10'
ddc:
- '530'
department:
- _id: AnSa
- _id: GradSch
doi: 10.1103/nbvt-fgjy
external_id:
  arxiv:
  - '2603.18918'
file:
- access_level: open_access
  checksum: 8ffb139122a185fcddbe6a9c901a287c
  content_type: application/pdf
  creator: dernst
  date_created: 2026-04-28T06:58:40Z
  date_updated: 2026-04-28T06:58:40Z
  file_id: '21769'
  file_name: 2026_PhysicalReviewLetters_Wassermair.pdf
  file_size: 4336488
  relation: main_file
  success: 1
file_date_updated: 2026-04-28T06:58:40Z
has_accepted_license: '1'
intvolume: '       136'
issue: '14'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '04'
oa: 1
oa_version: Published Version
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Navigating complex phase diagrams in soft matter systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21776'
abstract:
- lang: eng
  text: Pyridyl motifs equipped with N-substituents can be powerful ligands for catalysis,
    yet their broader adoption is limited by the lack of a practical method to prepare
    these scaffolds. We report a modular, robust, and versatile Buchwald–Hartwig amination
    protocol that enables the rapid synthesis of bipyridine, phenanthroline, terpyridine,
    and pybox ligands bearing dialkylamine, diarylamine, and heteroaromatic N-substituents.
    These conditions streamline ligand library synthesis and will facilitate systematic
    studies in catalysis and related applications.
acknowledged_ssus:
- _id: LifeSc
- _id: MassSpec
- _id: NMR
- _id: M-Shop
acknowledgement: We gratefully acknowledge ISTA for generous financial support. B.P.
  acknowledges the Austrian Science Fund (PAT 1250924) and the ACS GCI Pharmaceutical
  Roundtable for funding; T.P.Y acknowledges the NSF(CHE-2349003) for financial support.
  This research was supported by the Scientific Service Units (SSU) of ISTA through
  resources provided by the Lab Support Facility, Mass Spec Facility, NMR facility,
  and the Miba Machine Shop. We specifically thank Aikaterina Paraskevopoulou for
  HRMS measurements and Jan Pecak for support with ICP-OES experi-ments. NMR facilities
  at UW−Madison were supported by the NSF(CHE-1048642) and a generous gift from Paul
  J. and Margaret M. Bender. Open Access funding provided by Institute of Science
  and Technology Austria/KEMÖ. This study was supported by Austrian Science Fund (PAT
  1250924), ACSGCI Pharmaceutical Roundtable, and National Science Foundation(CHE-2349003)
  and (CHE-1048642).
article_number: e70417
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Adam
  full_name: Petrik, Adam
  id: e273d403-329f-11ee-a353-8c34c056f8ed
  last_name: Petrik
- first_name: Aleksander
  full_name: Bena, Aleksander
  id: 4197c39e-e8ec-11ed-86cb-afed934cd664
  last_name: Bena
- first_name: Haralds
  full_name: Baunis, Haralds
  id: 2eea55ec-e8ec-11ed-86cb-d9c76787acfe
  last_name: Baunis
- first_name: Riley M.
  full_name: Kelch, Riley M.
  last_name: Kelch
- first_name: Tehshik P.
  full_name: Yoon, Tehshik P.
  last_name: Yoon
- first_name: Bartholomäus
  full_name: Pieber, Bartholomäus
  id: 93e5e5b2-0da6-11ed-8a41-af589a024726
  last_name: Pieber
  orcid: 0000-0001-8689-388X
citation:
  ama: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. Facile access to N-substituted
    pyridyl ligands. <i>Advanced Synthesis &#38; Catalysis</i>. 2026;368(9). doi:<a
    href="https://doi.org/10.1002/adsc.70417">10.1002/adsc.70417</a>
  apa: Petrik, A., Bena, A., Baunis, H., Kelch, R. M., Yoon, T. P., &#38; Pieber,
    B. (2026). Facile access to N-substituted pyridyl ligands. <i>Advanced Synthesis
    &#38; Catalysis</i>. Wiley. <a href="https://doi.org/10.1002/adsc.70417">https://doi.org/10.1002/adsc.70417</a>
  chicago: Petrik, Adam, Aleksander Bena, Haralds Baunis, Riley M. Kelch, Tehshik
    P. Yoon, and Bartholomäus Pieber. “Facile Access to N-Substituted Pyridyl Ligands.”
    <i>Advanced Synthesis &#38; Catalysis</i>. Wiley, 2026. <a href="https://doi.org/10.1002/adsc.70417">https://doi.org/10.1002/adsc.70417</a>.
  ieee: A. Petrik, A. Bena, H. Baunis, R. M. Kelch, T. P. Yoon, and B. Pieber, “Facile
    access to N-substituted pyridyl ligands,” <i>Advanced Synthesis &#38; Catalysis</i>,
    vol. 368, no. 9. Wiley, 2026.
  ista: Petrik A, Bena A, Baunis H, Kelch RM, Yoon TP, Pieber B. 2026. Facile access
    to N-substituted pyridyl ligands. Advanced Synthesis &#38; Catalysis. 368(9),
    e70417.
  mla: Petrik, Adam, et al. “Facile Access to N-Substituted Pyridyl Ligands.” <i>Advanced
    Synthesis &#38; Catalysis</i>, vol. 368, no. 9, e70417, Wiley, 2026, doi:<a href="https://doi.org/10.1002/adsc.70417">10.1002/adsc.70417</a>.
  short: A. Petrik, A. Bena, H. Baunis, R.M. Kelch, T.P. Yoon, B. Pieber, Advanced
    Synthesis &#38; Catalysis 368 (2026).
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-05-05T00:00:00Z
date_updated: 2026-05-07T07:33:33Z
day: '05'
ddc:
- '540'
department:
- _id: BaPi
- _id: GradSch
doi: 10.1002/adsc.70417
file:
- access_level: open_access
  checksum: afe9752977898642c903abdc70b4a283
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-07T07:29:24Z
  date_updated: 2026-05-07T07:29:24Z
  file_id: '21833'
  file_name: 2026_AdvSynthCatal_Petrik.pdf
  file_size: 437184
  relation: main_file
  success: 1
file_date_updated: 2026-05-07T07:29:24Z
has_accepted_license: '1'
intvolume: '       368'
issue: '9'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 8f1d607d-16d5-11f0-9cad-ab453295ba5e
  grant_number: PAT 1250924
  name: Photoactive ligands for transformative nickel catalysis
publication: Advanced Synthesis & Catalysis
publication_identifier:
  eissn:
  - 1615-4169
  issn:
  - 1615-4150
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Facile access to N-substituted pyridyl ligands
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 368
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21777'
abstract:
- lang: eng
  text: The advantageous characteristics attributed to the 19F nucleus have made it
    a popular target for nuclear magnetic resonance (NMR) once again in recent years.
    Aside from solution NMR, an increasing number of studies have been conducted applying
    solid-state magic-angle spinning (MAS) NMR to fluorine-labelled samples. Here,
    the high chemical shift anisotropy and strong dipolar couplings can be utilised
    to get structural insights into proteins and measure long distances. Despite increasing
    popularity and promising benefits, the sensitivity of biomolecular 19F MAS NMR
    often suffers from slow longitudinal T1 relaxation and therefore long recycle
    delays. In this work, we expand paramagnetic doping, an approach commonly used
    to reduce proton T1 relaxation times, to 19F-labelled biological samples. We study
    the effect of Gd(DTPA) and Gd(DTPA-BMA) on 19F T1 and T2, and 13C T1 and T2 relaxation
    in a [5-19F13C]-tryptophan-labelled protein via 19F-detected MAS NMR experiments.
    The observed paramagnetic relaxation enhancement substantially reduces measurement
    times of 19F MAS NMR experiments without compromising resolution. Additionally,
    we report the chemical shift assignments of all four fluorotryptophan signals
    in the 12×39 kDa-large protein TET2 using a mutagenesis approach.
acknowledged_ssus:
- _id: NMR
- _id: LifeSc
acknowledgement: We thank Ben P. Tatman for insightful discussions. This research
  was supported by the Scientific Service Units (SSUs) of ISTA through resources provided
  by the Nuclear Magnetic Resonance Facility and the Lab Support Facility. We thank
  Prof. Tobias Madl (Medical University Graz) for a sample of Omniscan. Lea M. Becker
  is the recipient of a DOC fellowship of the Austrian Academy of Sciences at the
  Institute of Science and Technology Austria (grant no. PR10660EAW01).
article_processing_charge: Yes
article_type: original
author:
- first_name: Lea Marie
  full_name: Becker, Lea Marie
  id: 36336939-eb97-11eb-a6c2-c83f1214ca79
  last_name: Becker
  orcid: 0000-0002-6401-5151
- first_name: Giorgia
  full_name: Toscano, Giorgia
  id: 334a5e40-8747-11f0-b671-ba1f5154b4b4
  last_name: Toscano
- first_name: Anna
  full_name: Kapitonova, Anna
  id: 9fb2a840-89e1-11ee-a8b7-cc5c7ba62471
  last_name: Kapitonova
- first_name: Rajkumar
  full_name: Singh, Rajkumar
  id: a3089acd-6806-11ee-bacc-f0c7d500ad20
  last_name: Singh
- first_name: Undina
  full_name: Guillerm, Undina
  id: bb74f472-ae54-11eb-9835-bc9c22fb1183
  last_name: Guillerm
- first_name: Roman J.
  full_name: Lichtenecker, Roman J.
  last_name: Lichtenecker
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: Becker LM, Toscano G, Kapitonova A, et al. Accelerated 19F biomolecular magic-angle
    spinning NMR with paramagnetic dopants. <i>Magnetic Resonance</i>. 2026;7(1):29-37.
    doi:<a href="https://doi.org/10.5194/mr-7-29-2026">10.5194/mr-7-29-2026</a>
  apa: Becker, L. M., Toscano, G., Kapitonova, A., Singh, R., Guillerm, U., Lichtenecker,
    R. J., &#38; Schanda, P. (2026). Accelerated 19F biomolecular magic-angle spinning
    NMR with paramagnetic dopants. <i>Magnetic Resonance</i>. Copernicus Publications.
    <a href="https://doi.org/10.5194/mr-7-29-2026">https://doi.org/10.5194/mr-7-29-2026</a>
  chicago: Becker, Lea Marie, Giorgia Toscano, Anna Kapitonova, Rajkumar Singh, Undina
    Guillerm, Roman J. Lichtenecker, and Paul Schanda. “Accelerated 19F Biomolecular
    Magic-Angle Spinning NMR with Paramagnetic Dopants.” <i>Magnetic Resonance</i>.
    Copernicus Publications, 2026. <a href="https://doi.org/10.5194/mr-7-29-2026">https://doi.org/10.5194/mr-7-29-2026</a>.
  ieee: L. M. Becker <i>et al.</i>, “Accelerated 19F biomolecular magic-angle spinning
    NMR with paramagnetic dopants,” <i>Magnetic Resonance</i>, vol. 7, no. 1. Copernicus
    Publications, pp. 29–37, 2026.
  ista: Becker LM, Toscano G, Kapitonova A, Singh R, Guillerm U, Lichtenecker RJ,
    Schanda P. 2026. Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic
    dopants. Magnetic Resonance. 7(1), 29–37.
  mla: Becker, Lea Marie, et al. “Accelerated 19F Biomolecular Magic-Angle Spinning
    NMR with Paramagnetic Dopants.” <i>Magnetic Resonance</i>, vol. 7, no. 1, Copernicus
    Publications, 2026, pp. 29–37, doi:<a href="https://doi.org/10.5194/mr-7-29-2026">10.5194/mr-7-29-2026</a>.
  short: L.M. Becker, G. Toscano, A. Kapitonova, R. Singh, U. Guillerm, R.J. Lichtenecker,
    P. Schanda, Magnetic Resonance 7 (2026) 29–37.
corr_author: '1'
date_created: 2026-05-03T22:01:36Z
date_published: 2026-04-16T00:00:00Z
date_updated: 2026-05-07T06:49:59Z
day: '16'
ddc:
- '540'
department:
- _id: PaSc
- _id: GradSch
doi: 10.5194/mr-7-29-2026
external_id:
  pmid:
  - '42057802'
has_accepted_license: '1'
intvolume: '         7'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5194/mr-7-29-2026
month: '04'
oa: 1
oa_version: Published Version
page: 29-37
pmid: 1
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
- _id: 7be609c4-9f16-11ee-852c-85015ce2b9b0
  grant_number: '26777'
  name: Exploring protein dynamics by solid-state MAS NMR through specific labeling
    approaches
publication: Magnetic Resonance
publication_identifier:
  eissn:
  - 2699-0016
publication_status: published
publisher: Copernicus Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Accelerated 19F biomolecular magic-angle spinning NMR with paramagnetic dopants
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21845'
abstract:
- lang: eng
  text: UTe2 exhibits the remarkable phenomenon of re-entrant superconductivity, whereby
    the zero-resistance state reappears above 40 tesla after being suppressed with
    a field of around 10 tesla. One potential pairing mechanism, invoked in the related
    re-entrant superconductors UCoGe and URhGe, involves transverse fluctuations of
    a ferromagnetic order parameter. However, the requisite ferromagnetic order—present
    in both UCoGe and URhGe—is absent in UTe2, and neutron scattering shows instead
    that the magnetic susceptibility is peaked at an antiferromagnetic wavevector.
    Here, we measure the magnetotropic susceptibility of UTe2 across two field-angle
    planes. This quantity is sensitive to the magnetic susceptibility in a direction
    transverse to the applied magnetic field—a quantity that is not accessed in conventional
    magnetization measurements. We observe a very large decrease in the magnetotropic
    susceptibility over a broad range of field orientations, indicating a large increase
    in the transverse magnetic susceptibility. Because our technique probes the magnetic
    susceptibility in the long wavelength (q = 0) limit, this suggests that the strong
    transverse susceptibility arises from ferromagnetic spin fluctuations. These ferromagnetic
    fluctuations are likely important for understanding the pairing mechanism in UTe2,
    as all three superconducting phases of UTe2 surround this region of enhanced susceptibility
    in the field-angle phase diagram.
acknowledged_ssus:
- _id: NanoFab
acknowledgement: We appreciate technical support from Salvatore Bagiante, Evgeniia
  Volobueva, Lubuna Shafeek, Ali Bangura, and Zoltán Köllö, and scientific discussions
  with Daniel Agterberg, Johnpierre Paglione, Qimiao Si, Josephine Yu and Yue Yu.
  V.Z., A.N., M.N., and K.A.M. acknowledge funding received from the European Research
  Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (TROPIC-101078696). V.Z., A.N., M.N., and K.A.M. thank the ISTA Nanofabrication
  Facility for technical support. B.J.R. acknowledges funding from the Office of Basic
  Energy Sciences of the United States Department of Energy under award number DE-SC0020143
  for data analysis and writing. The National High Magnetic Field Laboratory is supported
  by the National Science Foundation through NSF/DMR-2128556*, the State of Florida,
  and the U.S. Department of Energy. A.S. acknowledges support from the DOE/BES “Science
  of 100 T” grant. A.S. thanks Downtown Subscription in Santa Fe, NM, for their patience
  in hosting him. Sample preparation and characterization were supported by the NSF
  through DMR-2105191.
article_number: '3742'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Valeska
  full_name: Zambra, Valeska
  id: 467ed36b-dc96-11ea-b7c8-b043a380b282
  last_name: Zambra
  orcid: 0000-0002-8806-5719
- first_name: Amit
  full_name: Nathwani, Amit
  id: 1a362536-4d02-11f1-8543-8351136efc50
  last_name: Nathwani
- first_name: Muhammad
  full_name: Nauman, Muhammad
  id: 32c21954-2022-11eb-9d5f-af9f93c24e71
  last_name: Nauman
  orcid: 0000-0002-2111-4846
- first_name: Sylvia K.
  full_name: Lewin, Sylvia K.
  last_name: Lewin
- first_name: Corey E.
  full_name: Frank, Corey E.
  last_name: Frank
- first_name: Nicholas P.
  full_name: Butch, Nicholas P.
  last_name: Butch
- first_name: Arkady
  full_name: Shekhter, Arkady
  last_name: Shekhter
- first_name: B. J.
  full_name: Ramshaw, B. J.
  last_name: Ramshaw
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
citation:
  ama: Zambra V, Nathwani A, Nauman M, et al. Giant transverse magnetic fluctuations
    at the edge of re-entrant superconductivity in UTe2. <i>Nature Communications</i>.
    2026;17. doi:<a href="https://doi.org/10.1038/s41467-026-71899-7">10.1038/s41467-026-71899-7</a>
  apa: Zambra, V., Nathwani, A., Nauman, M., Lewin, S. K., Frank, C. E., Butch, N.
    P., … Modic, K. A. (2026). Giant transverse magnetic fluctuations at the edge
    of re-entrant superconductivity in UTe2. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-026-71899-7">https://doi.org/10.1038/s41467-026-71899-7</a>
  chicago: Zambra, Valeska, Amit Nathwani, Muhammad Nauman, Sylvia K. Lewin, Corey
    E. Frank, Nicholas P. Butch, Arkady Shekhter, B. J. Ramshaw, and Kimberly A Modic.
    “Giant Transverse Magnetic Fluctuations at the Edge of Re-Entrant Superconductivity
    in UTe2.” <i>Nature Communications</i>. Springer Nature, 2026. <a href="https://doi.org/10.1038/s41467-026-71899-7">https://doi.org/10.1038/s41467-026-71899-7</a>.
  ieee: V. Zambra <i>et al.</i>, “Giant transverse magnetic fluctuations at the edge
    of re-entrant superconductivity in UTe2,” <i>Nature Communications</i>, vol. 17.
    Springer Nature, 2026.
  ista: Zambra V, Nathwani A, Nauman M, Lewin SK, Frank CE, Butch NP, Shekhter A,
    Ramshaw BJ, Modic KA. 2026. Giant transverse magnetic fluctuations at the edge
    of re-entrant superconductivity in UTe2. Nature Communications. 17, 3742.
  mla: Zambra, Valeska, et al. “Giant Transverse Magnetic Fluctuations at the Edge
    of Re-Entrant Superconductivity in UTe2.” <i>Nature Communications</i>, vol. 17,
    3742, Springer Nature, 2026, doi:<a href="https://doi.org/10.1038/s41467-026-71899-7">10.1038/s41467-026-71899-7</a>.
  short: V. Zambra, A. Nathwani, M. Nauman, S.K. Lewin, C.E. Frank, N.P. Butch, A.
    Shekhter, B.J. Ramshaw, K.A. Modic, Nature Communications 17 (2026).
corr_author: '1'
date_created: 2026-05-10T22:02:15Z
date_published: 2026-04-29T00:00:00Z
date_updated: 2026-05-11T06:36:00Z
day: '29'
ddc:
- '530'
department:
- _id: KiMo
- _id: GradSch
doi: 10.1038/s41467-026-71899-7
external_id:
  arxiv:
  - '2506.08984'
file:
- access_level: open_access
  checksum: 8cb95b033ad2a1a7a8181f6f078c05b5
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-11T06:32:12Z
  date_updated: 2026-05-11T06:32:12Z
  file_id: '21850'
  file_name: 2026_NatureComm_Zambra.pdf
  file_size: 1784917
  relation: main_file
  success: 1
file_date_updated: 2026-05-11T06:32:12Z
has_accepted_license: '1'
intvolume: '        17'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: bd968c70-d553-11ed-ba76-cde40b0aba64
  grant_number: '101078696'
  name: Gaining leverage with spin liquids and superconductors
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '21174'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Giant transverse magnetic fluctuations at the edge of re-entrant superconductivity
  in UTe2
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2026'
...
---
OA_place: publisher
_id: '21854'
abstract:
- lang: eng
  text: "As neural-network-based models grow both in size and popularity, interest
    has grown in making the models smaller and more efficient to train. To that end,
    many methods have been proposed to prune models by reducing their number of nonzero
    parameters. Additionally, parameter-efficient fine-tuning, in which a much smaller
    number of parameters than the total contained in the model is updated during training,
    has become very popular, especially in the space of Large Language Models. At
    the same time, the increasingly routine deployment of machine learning in real-world
    applications has spurred a drive to make them more trustworthy - in the sense
    of, among other things, being unbiased, interpretable, and editable. In this thesis,
    we examine the interplay between efficiency and trustworthiness.\r\n\r\nFirst,
    we analyze the effects of model pruning on bias in computer vision models, demonstrating
    that increased sparsity leads to greater bias, largely as a function of increased
    model uncertainty in marginal cases. Based on this observation, we propose several
    bias mitigation techniques. Then, we demonstrate that example-specific model pruning
    can improve model interpretation methods while improving pruning efficiency to
    make example-specific model pruning feasible in real time. Then, we investigate
    the effectiveness of parameter-efficient and data-efficient model personalization
    via fine-tuning, demonstrating that it is highly feasible with very small computational
    and data resources. Finally, we consider efficiency in editing model knowledge
    using a custom synthetic data framework, demonstrating that parameter-efficient,
    low-rank fine-tuning frequently outperforms full-rank fine-tuning, and, additionally,
    that restricting which model blocks are fine-tuned frequently improves results.
    Together, the results in this thesis provide new insights and techniques for combining
    trustworthiness and efficiency during neural network inference and training.\r\n\r\n-----------------“In
    reference to IEEE copyrighted material which is used with permission in this thesis,
    the IEEE does not endorse any of [name of university or educational entity]’s
    products or services. Internal or personal use of this material is permitted.
    If interested in reprinting/republishing IEEE copyrighted material for advertising
    or promotional purposes or for creating new collective works for resale or redistribution,
    please go to http://www.ieee.org/publications_standards/publications/rights/rights_link.html
    to learn how to obtain a License from RightsLink. If applicable, University Microfilms
    and/or ProQuest Library, or the Archives of Canada may supply single copies of
    the dissertation.”"
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "The research in this Ph.D. was funded in whole\r\nor in part by
  the Austrian Science Fund (FWF) W1260-N35 (Vienna Graduate School for\r\nComputational
  Optimization). For open access purposes the author has applied a CC BY\r\npublic
  copyright license to any author accepted manuscript version arising from this submission\r\nwherever
  possible. Additionally, I am grateful to Alois Schlögl, Waleed Khalid, and the rest
  of\r\nthe ISTA Scientific Computing team for building and maintaining the infrastructure
  I used\r\nto run experiments. I’m also deeply grateful to the Alistarh group’s administrative
  assistant,\r\nChristine Francois, who always deals with our nonsense with common
  sense and a smile.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Eugenia B
  full_name: Iofinova, Eugenia B
  id: f9a17499-f6e0-11ea-865d-fdf9a3f77117
  last_name: Iofinova
  orcid: 0000-0002-7778-3221
citation:
  ama: Iofinova EB. On the utility and effects of efficiency in artificial neural
    networks. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21854">10.15479/AT-ISTA-21854</a>
  apa: Iofinova, E. B. (2026). <i>On the utility and effects of efficiency in artificial
    neural networks</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21854">https://doi.org/10.15479/AT-ISTA-21854</a>
  chicago: Iofinova, Eugenia B. “On the Utility and Effects of Efficiency in Artificial
    Neural Networks.” Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21854">https://doi.org/10.15479/AT-ISTA-21854</a>.
  ieee: E. B. Iofinova, “On the utility and effects of efficiency in artificial neural
    networks,” Institute of Science and Technology Austria, 2026.
  ista: Iofinova EB. 2026. On the utility and effects of efficiency in artificial
    neural networks. Institute of Science and Technology Austria.
  mla: Iofinova, Eugenia B. <i>On the Utility and Effects of Efficiency in Artificial
    Neural Networks</i>. Institute of Science and Technology Austria, 2026, doi:<a
    href="https://doi.org/10.15479/AT-ISTA-21854">10.15479/AT-ISTA-21854</a>.
  short: E.B. Iofinova, On the Utility and Effects of Efficiency in Artificial Neural
    Networks, Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-05-11T08:43:22Z
date_published: 2026-05-11T00:00:00Z
date_updated: 2026-05-19T11:20:28Z
day: '11'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: GradSch
- _id: DaAl
doi: 10.15479/AT-ISTA-21854
file:
- access_level: closed
  checksum: 2e148dad920e3f9b7c32796e0ba2e5f7
  content_type: application/zip
  creator: eiofinov
  date_created: 2026-05-11T08:36:01Z
  date_updated: 2026-05-11T08:36:01Z
  file_id: '21856'
  file_name: EIofinova_thesis_FinalVersion.zip
  file_size: 28479571
  relation: source_file
- access_level: open_access
  checksum: b10c2933f386f532b2dbf28b19c5525c
  content_type: application/pdf
  creator: eiofinov
  date_created: 2026-05-13T13:10:48Z
  date_updated: 2026-05-13T13:10:48Z
  file_id: '21877'
  file_name: 2026_Iofinova_Eugenia_Thesis.pdf
  file_size: 18137757
  relation: main_file
  success: 1
file_date_updated: 2026-05-13T13:10:48Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '237'
project:
- _id: 9B9290DE-BA93-11EA-9121-9846C619BF3A
  grant_number: W1260-N35
  name: Vienna Graduate School on Computational Optimization
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '14771'
    relation: part_of_dissertation
    status: public
  - id: '18121'
    relation: part_of_dissertation
    status: public
  - id: '21858'
    relation: part_of_dissertation
    status: public
  - id: '21859'
    relation: part_of_dissertation
    status: public
  - id: '21857'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
title: On the utility and effects of efficiency in artificial neural networks
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
OA_type: green
_id: '21857'
abstract:
- lang: eng
  text: "The availability of powerful open-source large language models (LLMs) opens
    exciting use cases, such as using personal data to fine-tune these models to imitate
    a user’s unique writing style. Two key requirements for this functionality are
    personalization–in the sense that the output should recognizably reflect the user’s
    own writing style—and privacy–users may justifiably be wary of uploading extremely
    personal data, such as their email archive, to a third-party service. In this
    paper, we demonstrate the feasibility of training and running such an assistant,
    which we call Panza, on commodity hardware, for the specific use case of email
    generation. Panza’s personalization features are based on a combination of parameter-efficient
    fine-tuning using a variant of the Reverse Instructions technique [1] and Retrieval-Augmented
    Generation (RAG) [2]. We demonstrate that this combination allows us to fine-tune
    an LLM to reflect a user’s writing style using limited data, while executing on
    extremely limited resources, e.g. on a free Google Colab instance. Our key methodological
    contribution is the first detailed study of evaluation metrics for this task,
    and\r\nof how different choices of system components–the use of RAG and of different
    fine-tuning approaches–impact the system’s performance. Additionally, we demonstrate
    that very little data - under 100 email samples - are sufficient to create models
    that convincingly imitate humans, showcasing a previously unknown attack vector
    in language models. We are releasing the full Panza code as well as three new
    email datasets licensed for research use."
article_number: '81'
article_processing_charge: No
author:
- first_name: Armand
  full_name: Nicolicioiu, Armand
  last_name: Nicolicioiu
- first_name: Eugenia B
  full_name: Iofinova, Eugenia B
  id: f9a17499-f6e0-11ea-865d-fdf9a3f77117
  last_name: Iofinova
  orcid: 0000-0002-7778-3221
- first_name: Andrej
  full_name: Jovanovic, Andrej
  last_name: Jovanovic
- first_name: Eldar
  full_name: Kurtic, Eldar
  id: 47beb3a5-07b5-11eb-9b87-b108ec578218
  last_name: Kurtic
- first_name: Mahdi
  full_name: Nikdan, Mahdi
  id: 66374281-f394-11eb-9cf6-869147deecc0
  last_name: Nikdan
- first_name: Andrei
  full_name: Panferov, Andrei
  id: 2c18daae-4dbe-11ef-8491-98ce2d960f09
  last_name: Panferov
- first_name: Ilia
  full_name: Markov, Ilia
  id: D0CF4148-C985-11E9-8066-0BDEE5697425
  last_name: Markov
- first_name: Nir
  full_name: Shavit, Nir
  last_name: Shavit
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Nicolicioiu A, Iofinova EB, Jovanovic A, et al. <i>Panza: Investigating the
    Feasibility of Fully-Local Personalized Text Generation</i>. OpenReview; 2026.'
  apa: 'Nicolicioiu, A., Iofinova, E. B., Jovanovic, A., Kurtic, E., Nikdan, M., Panferov,
    A., … Alistarh, D.-A. (2026). <i>Panza: Investigating the feasibility of fully-local
    personalized text generation</i>. <i>Third Conference on Parsimony and Learning
    (Proceedings Track)</i>. Tübíngen, Germany: OpenReview.'
  chicago: 'Nicolicioiu, Armand, Eugenia B Iofinova, Andrej Jovanovic, Eldar Kurtic,
    Mahdi Nikdan, Andrei Panferov, Ilia Markov, Nir Shavit, and Dan-Adrian Alistarh.
    <i>Panza: Investigating the Feasibility of Fully-Local Personalized Text Generation</i>.
    <i>Third Conference on Parsimony and Learning (Proceedings Track)</i>. OpenReview,
    2026.'
  ieee: 'A. Nicolicioiu <i>et al.</i>, <i>Panza: Investigating the feasibility of
    fully-local personalized text generation</i>. OpenReview, 2026.'
  ista: 'Nicolicioiu A, Iofinova EB, Jovanovic A, Kurtic E, Nikdan M, Panferov A,
    Markov I, Shavit N, Alistarh D-A. 2026. Panza: Investigating the feasibility of
    fully-local personalized text generation, OpenReview,p.'
  mla: 'Nicolicioiu, Armand, et al. “Panza: Investigating the Feasibility of Fully-Local
    Personalized Text Generation.” <i>Third Conference on Parsimony and Learning (Proceedings
    Track)</i>, 81, OpenReview, 2026.'
  short: 'A. Nicolicioiu, E.B. Iofinova, A. Jovanovic, E. Kurtic, M. Nikdan, A. Panferov,
    I. Markov, N. Shavit, D.-A. Alistarh, Panza: Investigating the Feasibility of
    Fully-Local Personalized Text Generation, OpenReview, 2026.'
conference:
  end_date: 2026-03-26
  location: Tübíngen, Germany
  name: 'CPAL: Conference on Parsimony and Learning'
  start_date: 2026-03-23
corr_author: '1'
date_created: 2026-05-11T08:50:28Z
date_published: 2026-03-06T00:00:00Z
date_updated: 2026-05-19T11:20:27Z
day: '06'
department:
- _id: GradSch
- _id: DaAl
keyword:
- LLMs
- PEFT
- LoRA
- personalization
- efficient ML
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://openreview.net/pdf?id=soFWnTqd23
month: '03'
oa: 1
oa_version: Accepted Version
publication: Third Conference on Parsimony and Learning (Proceedings Track)
publication_status: published
publisher: OpenReview
quality_controlled: '1'
related_material:
  record:
  - id: '21854'
    relation: dissertation_contains
    status: public
status: public
title: 'Panza: Investigating the feasibility of fully-local personalized text generation'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference_poster
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21859'
abstract:
- lang: eng
  text: As artificial neural networks, and specifically large language models, have
    improved rapidly in capabilities and quality, they have increasingly been deployed
    in real-world applications, from customer service to Google search, despite the
    fact that they frequently make factually incorrect or undesirable statements.
    This trend has inspired practical and academic interest in model editing, that
    is, in adjusting the weights of the model to modify its likely outputs for queries
    relating to a specific fact or set of facts. This may be done either to amend
    a fact or set of facts, for instance, to fix a frequent error in the training
    data, or to suppress a fact or set of facts entirely, for instance, in case of
    dangerous knowledge. Multiple methods have been proposed to do such edits. However,
    at the same time, it has been shown that such model editing can be brittle and
    incomplete. Moreover the effectiveness of any model editing method necessarily
    depends on the data on which the model is trained, and, therefore, a good understanding
    of the interaction of the training data distribution and the way it is stored
    in the network is necessary and helpful to reliably perform model editing. However,
    working with large language models trained on real-world data does not allow us
    to understand this relationship or fully measure the effects of model editing.
    We therefore propose Behemoth, a fully synthetic data generation framework. To
    demonstrate the practical insights from the framework, we explore model editing
    in the context of simple tabular data, demonstrating surprising findings that,
    in some cases, echo real-world results, for instance, that in some cases restricting
    the update rank results in a more effective update.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "EI thanks Weiwei Yang, Janardhan Kulkani, and Kate Lytvynets for
  their advice and support in\r\ndeveloping an earlier version of the Behemoth library.
  This research was supported by the Scientific\r\nService Units (SSU) of IST Austria
  through resources provided by Scientific Computing (SciComp).\r\nEI was supported
  in part by the FWF DK VGSCO, grant agreement number W1260-N35.\r\n"
article_processing_charge: No
arxiv: 1
author:
- first_name: Eugenia B
  full_name: Iofinova, Eugenia B
  id: f9a17499-f6e0-11ea-865d-fdf9a3f77117
  last_name: Iofinova
  orcid: 0000-0002-7778-3221
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
citation:
  ama: 'Iofinova EB, Alistarh D-A. Behemoth: Benchmarking unlearning in LLMs using
    fully synthetic data. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2601.23153">10.48550/arXiv.2601.23153</a>'
  apa: 'Iofinova, E. B., &#38; Alistarh, D.-A. (n.d.). Behemoth: Benchmarking unlearning
    in LLMs using fully synthetic data. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2601.23153">https://doi.org/10.48550/arXiv.2601.23153</a>'
  chicago: 'Iofinova, Eugenia B, and Dan-Adrian Alistarh. “Behemoth: Benchmarking
    Unlearning in LLMs Using Fully Synthetic Data.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2601.23153">https://doi.org/10.48550/arXiv.2601.23153</a>.'
  ieee: 'E. B. Iofinova and D.-A. Alistarh, “Behemoth: Benchmarking unlearning in
    LLMs using fully synthetic data,” <i>arXiv</i>. .'
  ista: 'Iofinova EB, Alistarh D-A. Behemoth: Benchmarking unlearning in LLMs using
    fully synthetic data. arXiv, <a href="https://doi.org/10.48550/arXiv.2601.23153">10.48550/arXiv.2601.23153</a>.'
  mla: 'Iofinova, Eugenia B., and Dan-Adrian Alistarh. “Behemoth: Benchmarking Unlearning
    in LLMs Using Fully Synthetic Data.” <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/arXiv.2601.23153">10.48550/arXiv.2601.23153</a>.'
  short: E.B. Iofinova, D.-A. Alistarh, ArXiv (n.d.).
corr_author: '1'
date_created: 2026-05-11T08:58:07Z
date_published: 2026-01-30T00:00:00Z
date_updated: 2026-05-19T11:20:27Z
day: '30'
department:
- _id: GradSch
- _id: DaAl
doi: 10.48550/arXiv.2601.23153
external_id:
  arxiv:
  - '2601.23153'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2601.23153
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 9B9290DE-BA93-11EA-9121-9846C619BF3A
  grant_number: W1260-N35
  name: Vienna Graduate School on Computational Optimization
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '21854'
    relation: dissertation_contains
    status: public
status: public
title: 'Behemoth: Benchmarking unlearning in LLMs using fully synthetic data'
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
_id: '21863'
abstract:
- lang: eng
  text: "Atoms and photons, two things so different but yet so alike. The former,
    the building block of matter, something we learn about in school and imagine it
    as some tiny marbles encircled by other tinier marbles. The latter, an electromagnetic
    wave, a light particle or an excitation of the electromagnetic field. Quantum
    mechanics tells us about the properties of these two entities. And even if it
    sounds, looks and writes counter-intuitive, it has proven right for over a century
    now.\r\n\r\nIn this work, I elaborate on how we tested the laws of quantum mechanics
    and how we used them learn more about the tiny building blocks of nature and the
    fields they use to talk to each other. The atoms we use, are artificial. Superconducting
    qubits, small electrical circuits with quantized energy levels behave like electrons
    that transition between different orbitals in an atom. One of the qubits' advantages,
    is also a big disadvantage. We design the circuits' energy levels and fabricate
    them in a cleanroom. This allows for arbitrary spaced energy levels but in contrast
    to real atoms, prevents two superconducting qubits from being alike. Still, this
    qubit platform is one of the frontrunners for future quantum computing technology
    and testing fundamental physics due to their scalability.\r\n\r\nWe interface
    superconducting qubits, which operate in the GHz regime, with microwave photons.
    We use 3D aluminum cavities as mediators between qubits and photons. The cavities
    allow for non-destructive readout of the qubit state, they shield the qubits from
    noise at the qubit frequency and they give us an easy way to frequency-tune these
    joint systems.\r\n\r\nWe need to operate superconducting qubits and their cavities
    at millikelvin temperatures in dilution refrigerators. At higher temperatures,
    superconductivity suffers and even worse, the environment is filled with thermal
    noise photons. This poses a fundamental limitation on the scalability of superconducting
    qubit devices. Also connecting multiple devices in different fridges does not
    work over room temperature links because the microwave photons used for this purpose
    will be covered in noise and the quantum information they carry, will be unusable.\r\n\r\nInfrared
    photons do not suffer from this noise problem since there are close to zero thermal
    noise photons at their frequencies at room temperature. We cannot simply interface
    superconducting devices with optical photons due their frequency mismatch and
    the destructive effect of optical photons on superconductors. Therefore, we use
    microwave-to-optics transducers that allow to convert microwave photons into optical
    ones and vice-versa. The transducers that we use are macroscopic electro-optic
    transducers using the Pockels effect in a disk-shaped Lithium Niobate whispering
    gallery mode resonator. By using a strong optical pump, photons from the two frequency
    domains experience a beam-splitter interaction and get converted from one to the
    other.\r\n\r\nWe measure the generated optical photons using elaborate optical
    setups, optical heterodyning and single photon detectors to gain knowledge about
    the qubit state or the converted microwave photons. Bridging the microwave and
    the optical world allows us to take advantage of both of their strengths but it
    also requires deep knowledge about both of their working principles.\r\n\r\nIn
    this work, we describe two experiments that our group conducted to showcase the
    opportunities that arise from interfacing superconducting qubits with optical
    photons but also the pitfalls, one may encounter on the way.\r\n\r\nIn the first
    experiment, we managed to all-optically read out a superconducting qubit. We show
    that the assignment fidelity, the probability that a measurement of the qubit
    state matches the prepared state, is close to equal for all-optical, microwave-to-optics
    and conventional microwave readout. We show T1 and T2 measurements for all three
    readout types and give an analysis of the noise caused by the optics. Finally,
    we show that the infrared light does not affect the qubit performance in a negative
    way but that the heating it causes does. This is an important insight that we
    used in the next experiment.\r\n\r\nThe second experiment is the upconversion
    of itinerant single microwave photons to the optical domain. We show that we can
    generate single microwave photons from a qubit-cavity system. We upconvert these
    single photons, measure them with a single photon detector and reconstruct their
    shape. By conducting a single photon Rabi measurement, we show correlations between
    the microwave and the optical domain. And by thorough signal-to-noise measurements
    and noise analysis, we find that we can generate single infrared photons with
    high signal-to-noise ratio 5.1 and low transducer added noise (<0.012 quanta).
    We show that this measurement creates a path towards entanglement of a superconducting
    qubit and an optical photon and what parameters need to be improved to achieve
    it. Additionally, this experiment is a proof of principle for an on-demand infrared
    single photon source. More generally, it allows to link microwave quantum technology
    in general to the optical domain."
acknowledged_ssus:
- _id: M-Shop
- _id: NanoFab
- _id: LifeSc
- _id: SSU
acknowledgement: "The author of this work was supported by the European Research Council
  under grant no.\r\n101089099 (ERC CoG cQEO) and the European Union’s Horizon 2020
  research and innovation\r\nprogram under grant no. 899354 (FETopen SuperQuLAN).\r\nThis
  work was also supported by the European Research Council under grant nos. 758053\r\n(ERC
  StG QUNNECT), 101248662 (ERC POC CoupledEOT), and the European Innovation\r\nCouncil
  no. 101187231 (PathfinderOpen CIELO). This research was funded in whole or in part\r\nby
  the Austrian Science Fund (FWF) [10.55776/F71]. For open access purposes, the author\r\nhas
  applied a CC BY public copyright license to any author accepted manuscript version
  arising\r\nfrom this submission.\r\niii\r\nMy co-authors in the works mentioned
  later acknowledge generous support from the ISTFELLOW program, the NOMIS-ISTA fellowship,
  the Horizon Europe Program HORIZONCL4-2022-QUANTUM-01-SGA via Project No. 101113946
  OpenSuperQPlus100 and a DOC fellowship of the Austrian Academy of Sciences at IST
  Austria.\r\n"
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Werner, Thomas
  id: 1fcd8497-dba3-11ea-a45e-c6fbd715f7c7
  last_name: Werner
  orcid: 0009-0001-2346-5236
citation:
  ama: Werner T. Interfacing superconducting qubits with optical photons. 2026. doi:<a
    href="https://doi.org/10.15479/AT-ISTA-21863">10.15479/AT-ISTA-21863</a>
  apa: Werner, T. (2026). <i>Interfacing superconducting qubits with optical photons</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21863">https://doi.org/10.15479/AT-ISTA-21863</a>
  chicago: Werner, Thomas. “Interfacing Superconducting Qubits with Optical Photons.”
    Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21863">https://doi.org/10.15479/AT-ISTA-21863</a>.
  ieee: T. Werner, “Interfacing superconducting qubits with optical photons,” Institute
    of Science and Technology Austria, 2026.
  ista: Werner T. 2026. Interfacing superconducting qubits with optical photons. Institute
    of Science and Technology Austria.
  mla: Werner, Thomas. <i>Interfacing Superconducting Qubits with Optical Photons</i>.
    Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21863">10.15479/AT-ISTA-21863</a>.
  short: T. Werner, Interfacing Superconducting Qubits with Optical Photons, Institute
    of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-05-12T09:04:02Z
date_published: 2026-05-12T00:00:00Z
date_updated: 2026-05-20T13:35:43Z
day: '12'
ddc:
- '530'
- '537'
- '539'
degree_awarded: PhD
department:
- _id: GradSch
- _id: JoFi
doi: 10.15479/AT-ISTA-21863
ec_funded: 1
file:
- access_level: open_access
  checksum: a5b4d8dba83f96e955a3625c0eebee98
  content_type: application/pdf
  creator: twerner
  date_created: 2026-05-15T15:53:57Z
  date_updated: 2026-05-15T15:53:57Z
  file_id: '21879'
  file_name: 2026_Werner_Thomas_Thesis.pdf
  file_size: 9330516
  relation: main_file
- access_level: closed
  checksum: b41282beaacfb32472769b9e3b1758d8
  content_type: application/x-zip-compressed
  creator: twerner
  date_created: 2026-05-15T15:54:06Z
  date_updated: 2026-05-15T15:54:06Z
  file_id: '21880'
  file_name: 2026_Werner_Thomas_Thesis.zip
  file_size: 9370704
  relation: source_file
file_date_updated: 2026-05-15T15:54:06Z
has_accepted_license: '1'
keyword:
- Superconducting qubits
- Quantum optics
- Single photons and quantum effects
- Nonlinear optics
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '97'
project:
- _id: bdadfa0d-d553-11ed-ba76-fb85edbd456a
  grant_number: '101089099'
  name: 'Cavity Quantum Electro Optics: Microwave photonics with nonclassical states'
- _id: 9B868D20-BA93-11EA-9121-9846C619BF3A
  call_identifier: H2020
  grant_number: '899354'
  name: Quantum Local Area Networks with Superconducting Qubits
- _id: 26336814-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '758053'
  name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 5b807754-ab3d-11f0-914f-ff8c34502cc9
  grant_number: '101248662'
  name: Integrated optical coupling for low loss electro-optic interconnects
- _id: 91aaf765-16d5-11f0-9cad-a8e7e44cccb7
  grant_number: '101187231'
  name: 'Cavity-Integrated Electro-Optics: Measuring, Converting and Manipulating
    Microwaves with Light'
- _id: bdb108fd-d553-11ed-ba76-83dc74a9864f
  grant_number: F07105
  name: QUANTUM INFORMATION SYSTEMS BEYOND CLASSICAL CAPABILITIES / P5- Integration
    of Superconducting Quantum Circuits
- _id: bdb7cfc1-d553-11ed-ba76-d2eaab167738
  grant_number: '101080139'
  name: Open Superconducting Quantum Computers (OpenSuperQPlus)
- _id: 9B861AAC-BA93-11EA-9121-9846C619BF3A
  name: NOMIS Fellowship Program
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '19073'
    relation: part_of_dissertation
    status: public
  - id: '21870'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
title: Interfacing superconducting qubits with optical photons
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21870'
abstract:
- lang: eng
  text: Superconducting qubits are a leading candidate for utility-scale quantum computing
    due to their fast gate speeds and steadily decreasing error rates. The requirement
    for millikelvin operating temperatures, however, creates a significant scaling
    bottleneck. Modular architectures using optical fiber links could bridge separate
    cryogenic nodes, but superconducting circuits do not have coherent optical transitions
    and microwave-to-optical conversion has not been shown for any non-classical photon
    state. In this work, we demonstrate the on-demand generation and tomographic reconstruction
    of itinerant single microwave photons at 8.9 GHz from a superconducting qubit.
    We upconvert this non-Gaussian state with a transducer added noise below 0.012
    quanta and count the converted telecom photons at 193.4 THz with a signal-to-noise
    ratio of up to 5.1$\pm$1.1. We characterize the trade-offs between throughput
    and noise, and establish a viable path toward heralded entanglement distribution
    and gate teleportation. Looking ahead, these results empower existing superconducting
    devices to take a key role in distributed quantum technologies and heterogeneous
    quantum systems.
acknowledgement: "We thank Fritz Diorico and Onur Hosten who suggested the filter
  cavity design, and gave important insights about the assembly and the testing of
  the FabryPerot filter cavities. Ekatrina Fedotova and Diego A.\r\nLancheros Naranjo
  worked on the filter cavity setup in\r\nthe early stages of this work. Gustavo Wiederhecker
  and\r\nYiewen Chu provided insights as to the origins of the\r\nobserved optical
  noise and Nicola Carlon Zambon suggested using telecom filters to mitigate it further.
  This\r\nwork was supported by the European Research Council under grant agreement
  no. 101089099 (ERC CoG\r\ncQEO), and 101248662 (ERC POC CoupledEOT), the\r\nEuropean
  Unions Horizon 2020 research and innovation\r\nprogram under grant agreement no.
  899354 (FETopen\r\nSuperQuLAN), the European Innovation Council no.\r\n101187231
  (PathfinderOpen CIELO), and the Austrian\r\nScience Fund (FWF) no. F7105 (SFB BeyondC).
  J.F.\r\nand L.K. acknowledge support from the Horizon Europe\r\nProgram HORIZON-CL4-2022-QUANTUM-01-SGA
  via\r\nProject No. 101113946 OpenSuperQPlus100. A.M. acknowledges support from the
  NOMIS-ISTA fellowship."
article_processing_charge: No
arxiv: 1
author:
- first_name: Thomas
  full_name: Werner, Thomas
  id: 1fcd8497-dba3-11ea-a45e-c6fbd715f7c7
  last_name: Werner
  orcid: 0009-0001-2346-5236
- first_name: Erfan
  full_name: Riyazi, Erfan
  id: 53322f94-5355-11ee-ae5a-ff6f81c87d51
  last_name: Riyazi
- first_name: Samarth
  full_name: Hawaldar, Samarth
  id: 221708e1-1ff6-11ee-9fa6-85146607433e
  last_name: Hawaldar
  orcid: 0000-0002-1965-4309
- first_name: Rishabh
  full_name: Sahu, Rishabh
  id: 47D26E34-F248-11E8-B48F-1D18A9856A87
  last_name: Sahu
  orcid: 0000-0001-6264-2162
- first_name: Georg M
  full_name: Arnold, Georg M
  id: 3770C838-F248-11E8-B48F-1D18A9856A87
  last_name: Arnold
  orcid: 0000-0003-1397-7876
- first_name: Paul Falthansl-Scheinecker
  full_name: Paul Falthansl-Scheinecker, Paul Falthansl-Scheinecker
  last_name: Paul Falthansl-Scheinecker
- first_name: Jennifer A. Sánchez
  full_name: Naranjo, Jennifer A. Sánchez
  last_name: Naranjo
- first_name: Dante
  full_name: Loi, Dante
  last_name: Loi
- first_name: Lucky N.
  full_name: Kapoor, Lucky N.
  last_name: Kapoor
- first_name: Martin
  full_name: Zemlicka, Martin
  id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
  last_name: Zemlicka
  orcid: 0009-0005-0878-3032
- first_name: Liu
  full_name: Qiu, Liu
  id: 45e99c0d-1eb1-11eb-9b96-ed8ab2983cac
  last_name: Qiu
  orcid: 0000-0003-4345-4267
- first_name: Andrei
  full_name: Militaru, Andrei
  id: d67706f8-8eb1-11ee-ad1b-9c30dfa19e0b
  last_name: Militaru
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: Werner T, Riyazi E, Hawaldar S, et al. Electro-optic conversion of itinerant
    Fock states. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2602.00928">10.48550/arXiv.2602.00928</a>
  apa: Werner, T., Riyazi, E., Hawaldar, S., Sahu, R., Arnold, G. M., Paul Falthansl-Scheinecker,
    P. F.-S., … Fink, J. M. (n.d.). Electro-optic conversion of itinerant Fock states.
    <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2602.00928">https://doi.org/10.48550/arXiv.2602.00928</a>
  chicago: Werner, Thomas, Erfan Riyazi, Samarth Hawaldar, Rishabh Sahu, Georg M Arnold,
    Paul Falthansl-Scheinecker Paul Falthansl-Scheinecker, Jennifer A. Sánchez Naranjo,
    et al. “Electro-Optic Conversion of Itinerant Fock States.” <i>ArXiv</i>, n.d.
    <a href="https://doi.org/10.48550/arXiv.2602.00928">https://doi.org/10.48550/arXiv.2602.00928</a>.
  ieee: T. Werner <i>et al.</i>, “Electro-optic conversion of itinerant Fock states,”
    <i>arXiv</i>. .
  ista: Werner T, Riyazi E, Hawaldar S, Sahu R, Arnold GM, Paul Falthansl-Scheinecker
    PF-S, Naranjo JAS, Loi D, Kapoor LN, Zemlicka M, Qiu L, Militaru A, Fink JM. Electro-optic
    conversion of itinerant Fock states. arXiv, <a href="https://doi.org/10.48550/arXiv.2602.00928">10.48550/arXiv.2602.00928</a>.
  mla: Werner, Thomas, et al. “Electro-Optic Conversion of Itinerant Fock States.”
    <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/arXiv.2602.00928">10.48550/arXiv.2602.00928</a>.
  short: T. Werner, E. Riyazi, S. Hawaldar, R. Sahu, G.M. Arnold, P.F.-S. Paul Falthansl-Scheinecker,
    J.A.S. Naranjo, D. Loi, L.N. Kapoor, M. Zemlicka, L. Qiu, A. Militaru, J.M. Fink,
    ArXiv (n.d.).
corr_author: '1'
date_created: 2026-05-12T13:58:18Z
date_published: 2026-01-31T00:00:00Z
date_updated: 2026-05-20T13:35:42Z
day: '31'
department:
- _id: JoFi
- _id: GradSch
doi: 10.48550/arXiv.2602.00928
ec_funded: 1
external_id:
  arxiv:
  - '2602.00928'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2602.00928
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: bdadfa0d-d553-11ed-ba76-fb85edbd456a
  grant_number: '101089099'
  name: 'Cavity Quantum Electro Optics: Microwave photonics with nonclassical states'
- _id: 5b807754-ab3d-11f0-914f-ff8c34502cc9
  grant_number: '101248662'
  name: Integrated optical coupling for low loss electro-optic interconnects
- _id: 9B868D20-BA93-11EA-9121-9846C619BF3A
  call_identifier: H2020
  grant_number: '899354'
  name: Quantum Local Area Networks with Superconducting Qubits
- _id: 91aaf765-16d5-11f0-9cad-a8e7e44cccb7
  grant_number: '101187231'
  name: 'Cavity-Integrated Electro-Optics: Measuring, Converting and Manipulating
    Microwaves with Light'
- _id: 26927A52-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: F07105
  name: Integrating superconducting quantum circuits
- _id: 9B861AAC-BA93-11EA-9121-9846C619BF3A
  name: NOMIS Fellowship Program
publication: arXiv
publication_status: draft
related_material:
  record:
  - id: '21863'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Electro-optic conversion of itinerant Fock states
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
DOAJ_listed: '1'
OA_place: publisher
OA_type: gold
PlanS_conform: '1'
_id: '21917'
abstract:
- lang: eng
  text: A defining feature of quantum many-body systems is the exponential scaling
    of the Hilbert space with the number of degrees of freedom. This exponential complexity
    naïvely renders a complete state characterization, for instance via the complete
    set of bipartite Renyi entropies for all disjoint regions, a challenging task.
    Recently, a compact way of storing subregions' purities by encoding them as amplitudes
    of a fictitious quantum wave function, known as entanglement feature, was proposed.
    Notably, the entanglement feature can be a simple object even for highly entangled
    quantum states. However the complexity and practical usage of the entanglement
    feature for general quantum states has not been explored. In this work, we demonstrate
    that the entanglement feature can be efficiently learned using only a polynomial
    amount of samples in the number of degrees of freedom through the so-called tensor
    cross interpolation (TCI) algorithm, assuming it is expressible as a finite bond
    dimension MPS. We benchmark this learning process on Haar and random MPS states,
    confirming analytic expectations. Applying the TCI algorithm to quantum eigenstates
    of various one dimensional quantum systems, we identify cases where eigenstates
    have entanglement feature learnable with TCI. We conclude with possible applications
    of the learned entanglement feature, such as quantifying the distance between
    different entanglement patterns and finding the optimal one-dimensional ordering
    of physical indices in a given state, highlighting the potential utility of the
    proposed purity interpolation method.
acknowledgement: "We acknowledge useful discussions with Richard Küng\r\non the interpolation
  methods and error spreading, Ilia\r\nA. Luchnikov, Margarita Davydova, and, in particular,
  Hiroshi Shinaoka, Marc Ritter, Yuriel Nuñez\r\nfor useful discussions about TCI
  and the various\r\nworkarounds within the TensorCrossInterpolation.jl\r\nlibrary.
  We also acknowledge the comments of anonymous Referee B, that encouraged us to expand
  the\r\nmanuscript with discussion of additional applications\r\nof entanglement
  feature in Section 4.3. M.S. acknowledges discussions with D. V. Savostyanov at
  the 2nd\r\nInternational Quantum Tensor Networks (IQTN) plenary meeting at Flatiron
  Institute’s Center for Computational Quantum Physics (CCQ) for introduction\r\nto
  the TCI approach. D.K and M.S. acknowledge support by the European Research Council
  (ERC) under We acknowledge useful discussions with Richard Küng\r\non the interpolation
  methods and error spreading, Ilia\r\nA. Luchnikov, Margarita Davydova, and, in particular,
  Hiroshi Shinaoka, Marc Ritter, Yuriel Nuñez\r\nfor useful discussions about TCI
  and the various\r\nworkarounds within the TensorCrossInterpolation.jl\r\nlibrary.
  We also acknowledge the comments of anonymous Referee B, that encouraged us to expand
  the\r\nmanuscript with discussion of additional applications\r\nof entanglement
  feature in Section 4.3. M.S. acknowledges discussions with D. V. Savostyanov at
  the 2nd\r\nInternational Quantum Tensor Networks (IQTN) plenary meeting at Flatiron
  Institute’s Center for Computational Quantum Physics (CCQ) for introduction\r\nto
  the TCI approach. D.K and M.S. acknowledge support by the European Research Council
  (ERC) under We acknowledge useful discussions with Richard Küng\r\non the interpolation
  methods and error spreading, Ilia\r\nA. Luchnikov, Margarita Davydova, and, in particular,
  Hiroshi Shinaoka, Marc Ritter, Yuriel Nuñez\r\nfor useful discussions about TCI
  and the various\r\nworkarounds within the TensorCrossInterpolation.jl\r\nlibrary.
  We also acknowledge the comments of anonymous Referee B, that encouraged us to expand
  the\r\nmanuscript with discussion of additional applications\r\nof entanglement
  feature in Section 4.3. M.S. acknowledges discussions with D. V. Savostyanov at
  the 2nd\r\nInternational Quantum Tensor Networks (IQTN) plenary meeting at Flatiron
  Institute’s Center for Computational Quantum Physics (CCQ) for introduction\r\nto
  the TCI approach. D.K and M.S. acknowledge support by the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation program (Grant
  Agreement No. 850899).\r\nR.V. acknowledges partial support from the US Department
  of Energy, Office of Science, Basic Energy\r\nSciences, under award No. DE-SC0023999,
  and the\r\nSwiss National Science Foundation (grant 10008234).\r\nThis research
  was supported in part by grant NSF\r\nPHY-2309135 to the Kavli Institute for Theoretical\r\nPhysics
  (KITP)"
article_number: '2114'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Dmytro
  full_name: Kolisnyk, Dmytro
  id: 530a7320-5355-11ee-ae5a-82a46997aaa7
  last_name: Kolisnyk
  orcid: 0000-0002-8612-8202
- first_name: Raimel A
  full_name: Medina Ramos, Raimel A
  id: CE680B90-D85A-11E9-B684-C920E6697425
  last_name: Medina Ramos
  orcid: 0000-0002-5383-2869
- first_name: Romain
  full_name: Vasseur, Romain
  last_name: Vasseur
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: Kolisnyk D, Medina Ramos RA, Vasseur R, Serbyn M. Tensor cross interpolation
    of purities in quantum many-body systems. <i>Quantum</i>. 2026;10. doi:<a href="https://doi.org/10.22331/q-2026-05-22-2114">10.22331/q-2026-05-22-2114</a>
  apa: Kolisnyk, D., Medina Ramos, R. A., Vasseur, R., &#38; Serbyn, M. (2026). Tensor
    cross interpolation of purities in quantum many-body systems. <i>Quantum</i>.
    Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften.
    <a href="https://doi.org/10.22331/q-2026-05-22-2114">https://doi.org/10.22331/q-2026-05-22-2114</a>
  chicago: Kolisnyk, Dmytro, Raimel A Medina Ramos, Romain Vasseur, and Maksym Serbyn.
    “Tensor Cross Interpolation of Purities in Quantum Many-Body Systems.” <i>Quantum</i>.
    Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften,
    2026. <a href="https://doi.org/10.22331/q-2026-05-22-2114">https://doi.org/10.22331/q-2026-05-22-2114</a>.
  ieee: D. Kolisnyk, R. A. Medina Ramos, R. Vasseur, and M. Serbyn, “Tensor cross
    interpolation of purities in quantum many-body systems,” <i>Quantum</i>, vol.
    10. Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften,
    2026.
  ista: Kolisnyk D, Medina Ramos RA, Vasseur R, Serbyn M. 2026. Tensor cross interpolation
    of purities in quantum many-body systems. Quantum. 10, 2114.
  mla: Kolisnyk, Dmytro, et al. “Tensor Cross Interpolation of Purities in Quantum
    Many-Body Systems.” <i>Quantum</i>, vol. 10, 2114, Verein zur Förderung des Open
    Access Publizierens in den Quantenwissenschaften, 2026, doi:<a href="https://doi.org/10.22331/q-2026-05-22-2114">10.22331/q-2026-05-22-2114</a>.
  short: D. Kolisnyk, R.A. Medina Ramos, R. Vasseur, M. Serbyn, Quantum 10 (2026).
corr_author: '1'
date_created: 2026-05-26T19:39:12Z
date_published: 2026-05-22T00:00:00Z
date_updated: 2026-06-02T09:15:13Z
day: '22'
ddc:
- '530'
department:
- _id: MaSe
- _id: GradSch
doi: 10.22331/q-2026-05-22-2114
ec_funded: 1
external_id:
  arxiv:
  - '2503.17230'
file:
- access_level: open_access
  checksum: f8ce78607ad06120cdf894dc8cef55da
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-02T09:12:11Z
  date_updated: 2026-06-02T09:12:11Z
  file_id: '21939'
  file_name: 2026_Quantum_Kolisnyk.pdf
  file_size: 3284798
  relation: main_file
  success: 1
file_date_updated: 2026-06-02T09:12:11Z
has_accepted_license: '1'
intvolume: '        10'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Quantum
publication_identifier:
  eissn:
  - 2521-327X
publication_status: published
publisher: Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften
quality_controlled: '1'
status: public
title: Tensor cross interpolation of purities in quantum many-body systems
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2026'
...
---
OA_place: publisher
_id: '21918'
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "At different stages of my PhD, my work was supported by several
  grants: the\r\nDOC fellowship of the Austrian Academy of Sciences (26293, awarded
  to me),\r\nthe FWF-SFB grant (PT1032F06504 n. F65, awarded to Jan Maas), and the
  ERC\r\ngrant (PR1032ERC01 n. 716117, awarded to Jan Maas). I also appreciate the
  help\r\nfrom the Scientific Computing unit for their advice on the cluster usage."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Kseniia
  full_name: Khudiakova, Kseniia
  id: 4E6DC800-AE37-11E9-AC72-31CAE5697425
  last_name: Khudiakova
  orcid: 0000-0002-6246-1465
citation:
  ama: Khudiakova K. How epistasis and purifying selection shape genetic diversity.
    2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21918">10.15479/AT-ISTA-21918</a>
  apa: Khudiakova, K. (2026). <i>How epistasis and purifying selection shape genetic
    diversity</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21918">https://doi.org/10.15479/AT-ISTA-21918</a>
  chicago: Khudiakova, Kseniia. “How Epistasis and Purifying Selection Shape Genetic
    Diversity.” Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21918">https://doi.org/10.15479/AT-ISTA-21918</a>.
  ieee: K. Khudiakova, “How epistasis and purifying selection shape genetic diversity,”
    Institute of Science and Technology Austria, 2026.
  ista: Khudiakova K. 2026. How epistasis and purifying selection shape genetic diversity.
    Institute of Science and Technology Austria.
  mla: Khudiakova, Kseniia. <i>How Epistasis and Purifying Selection Shape Genetic
    Diversity</i>. Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21918">10.15479/AT-ISTA-21918</a>.
  short: K. Khudiakova, How Epistasis and Purifying Selection Shape Genetic Diversity,
    Institute of Science and Technology Austria, 2026.
corr_author: '1'
date_created: 2026-05-27T06:26:08Z
date_published: 2026-06-07T00:00:00Z
date_updated: 2026-06-12T12:43:35Z
day: '07'
ddc:
- '576'
degree_awarded: PhD
department:
- _id: GradSch
- _id: NiBa
- _id: JaMa
doi: 10.15479/AT-ISTA-21918
ec_funded: 1
file:
- access_level: closed
  checksum: 0cff64ae74f0f9f2d7011700c82f700a
  content_type: application/x-zip-compressed
  creator: kkhudiak
  date_created: 2026-06-09T08:34:38Z
  date_updated: 2026-06-09T08:40:48Z
  file_id: '21965'
  file_name: thesis.zip
  file_size: 20549813
  relation: source_file
- access_level: closed
  checksum: 547ae42de37cc86894af283f1664dbc8
  content_type: application/pdf
  creator: kkhudiak
  date_created: 2026-06-09T12:28:51Z
  date_updated: 2026-06-11T12:14:53Z
  embargo: 2027-06-10
  embargo_to: open_access
  file_id: '21969'
  file_name: 2026_Khudiakova_Ksenia_Thesis.pdf
  file_size: 9387029
  relation: main_file
file_date_updated: 2026-06-11T12:14:53Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '06'
oa_version: Published Version
page: '89'
project:
- _id: 256E75B8-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '716117'
  name: Optimal Transport and Stochastic Dynamics
- _id: 34d33d68-11ca-11ed-8bc3-ec13763c0ca8
  grant_number: '26293'
  name: The impact of deleterious mutations on small populations
- _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2
  grant_number: F6504
  name: Taming Complexity in Partial Differential Systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '11447'
    relation: part_of_dissertation
    status: public
  - id: '12513'
    relation: part_of_dissertation
    status: deleted
  - id: '21967'
    relation: part_of_dissertation
    status: public
  - id: '21968'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
title: How epistasis and purifying selection shape genetic diversity
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
_id: '21923'
abstract:
- lang: eng
  text: "The appearance of simulated natural phenomena heavily depends on the way
    surfaces are textured. However, applying texture maps to dynamic deformable surfaces
    presents a significant challenge, due to ever-shifting differences in length scales
    involved. When these surfaces move and advect the texture along with them, their
    final appearance degrades as deformed regions dramatically distort their texture
    map. Modifications to the texture directly at the pixel level in response to the
    deformation may introduce ghosting artifacts and look unnatural. In the real world,
    the appearance of surface details on a deforming material changes through the
    interplay of physical processes such as rupturing, exposure of internal structure,
    or wrinkling. Motivated by these behaviors, in this work we explore how physical
    principles can guide the texturing methods based on the measure of surface deformation.\r\nWe
    present two novel wave-based procedural texturing algorithms which reproduce common
    physical properties like advection and self-similarity, enabling the plausible
    animation of deforming objects with extreme texture map distortions. Our algorithms
    are fully procedural, require no actual physics simulation, and store no state
    or history of deformation besides the input UV map, making them highly parallelizable
    on the GPU and efficient enough for real-time applications. We show the versatility
    of the method by animating physical phenomena with extreme deformations such as
    flowing lava, stretching putty and outpouring sludge."
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank the anonymous reviewers for their helpful comments, the
  members of the Visual Computing Group at ISTA for their feedback. We also thank
  Jonathan Gagnon for their help with running the Lapped Textures codes and SideFX
  for the Houdini Education software licenses.\r\nImages in Fig. 2 by Kisoulou and
  Vultured on Unsplash, Michal Jarmoluk and Public Domain Pictures from Pixabay and
  Hawai‘i Volcanoes NPS on flickr. This research was supported by the Scientific Service
  Units (SSU) of ISTA through resources provided by Scientific Computing and was funded
  in part by the European Union (ERC-2021-COG 101045083 CoDiNA)."
article_number: '154'
article_processing_charge: Yes
article_type: original
author:
- first_name: Aleksei
  full_name: Kalinov, Aleksei
  id: 44b7120e-eb97-11eb-a6c2-e1557aa81d02
  last_name: Kalinov
  orcid: 0000-0003-2189-3904
- first_name: Mickaël
  full_name: Ly, Mickaël
  id: 6340d7f0-b48d-11eb-b10d-b7487e71d9f1
  last_name: Ly
- first_name: Christian
  full_name: Hafner, Christian
  id: 400429CC-F248-11E8-B48F-1D18A9856A87
  last_name: Hafner
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
citation:
  ama: Kalinov A, Ly M, Hafner C, Wojtan C. Physics-inspired procedural texturing
    of extremely deformable surfaces. <i>ACM Transactions on Graphics</i>. 45(4).
    doi:<a href="https://doi.org/10.1145/3811353">10.1145/3811353</a>
  apa: 'Kalinov, A., Ly, M., Hafner, C., &#38; Wojtan, C. (n.d.). Physics-inspired
    procedural texturing of extremely deformable surfaces. <i>ACM Transactions on
    Graphics</i>. Los Angeles, CA, United States: ACM. <a href="https://doi.org/10.1145/3811353">https://doi.org/10.1145/3811353</a>'
  chicago: Kalinov, Aleksei, Mickaël Ly, Christian Hafner, and Chris Wojtan. “Physics-Inspired
    Procedural Texturing of Extremely Deformable Surfaces.” <i>ACM Transactions on
    Graphics</i>. ACM, n.d. <a href="https://doi.org/10.1145/3811353">https://doi.org/10.1145/3811353</a>.
  ieee: A. Kalinov, M. Ly, C. Hafner, and C. Wojtan, “Physics-inspired procedural
    texturing of extremely deformable surfaces,” <i>ACM Transactions on Graphics</i>,
    vol. 45, no. 4. ACM.
  ista: Kalinov A, Ly M, Hafner C, Wojtan C. Physics-inspired procedural texturing
    of extremely deformable surfaces. ACM Transactions on Graphics. 45(4), 154.
  mla: Kalinov, Aleksei, et al. “Physics-Inspired Procedural Texturing of Extremely
    Deformable Surfaces.” <i>ACM Transactions on Graphics</i>, vol. 45, no. 4, 154,
    ACM, doi:<a href="https://doi.org/10.1145/3811353">10.1145/3811353</a>.
  short: A. Kalinov, M. Ly, C. Hafner, C. Wojtan, ACM Transactions on Graphics 45
    (n.d.).
conference:
  end_date: 2026-07-23
  location: Los Angeles, CA, United States
  name: 'SIGGRAPH: International Conference and Exhibition on Computer Graphics and
    Interactive Techniques'
  start_date: 2026-07-19
corr_author: '1'
date_created: 2026-05-29T13:25:16Z
date_published: 2026-07-01T00:00:00Z
date_updated: 2026-06-02T08:56:50Z
day: '01'
ddc:
- '006'
department:
- _id: GradSch
- _id: ChWo
doi: 10.1145/3811353
file:
- access_level: open_access
  checksum: ea165bf731ddd3045f83878dcb833672
  content_type: video/mp4
  creator: akalinov
  date_created: 2026-05-29T13:19:33Z
  date_updated: 2026-05-29T13:19:33Z
  file_id: '21924'
  file_name: tog454-article154-supplemental.mp4
  file_size: 77337231
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 6274cfb15ea5ba7324b74afc7b0d9629
  content_type: video/mp4
  creator: akalinov
  date_created: 2026-05-29T13:19:37Z
  date_updated: 2026-05-29T13:19:37Z
  file_id: '21925'
  file_name: tog454-article154-video.mp4
  file_size: 226633977
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 9d41b322a7876be9a3311017b9973183
  content_type: application/pdf
  creator: akalinov
  date_created: 2026-05-29T13:19:33Z
  date_updated: 2026-05-29T13:19:33Z
  file_id: '21926'
  file_name: tog454-article154-supplemental.pdf
  file_size: 6793867
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 51bc60d2de867fbfa570652dec7993b4
  content_type: application/pdf
  creator: akalinov
  date_created: 2026-05-29T13:19:36Z
  date_updated: 2026-05-29T13:19:36Z
  file_id: '21927'
  file_name: tog454-article154-main-1.pdf
  file_size: 84173392
  relation: main_file
  success: 1
file_date_updated: 2026-05-29T13:19:37Z
has_accepted_license: '1'
intvolume: '        45'
issue: '4'
keyword:
- Procedural animation
language:
- iso: eng
month: '07'
oa: 1
oa_version: Accepted Version
project:
- _id: 34bc2376-11ca-11ed-8bc3-9a3b3961a088
  grant_number: '101045083'
  name: Computational Discovery of Numerical Algorithms for Animation and Simulation
    of Natural Phenomena
publication: ACM Transactions on Graphics
publication_identifier:
  issn:
  - 0730-0301
publication_status: inpress
publisher: ACM
quality_controlled: '1'
status: public
title: Physics-inspired procedural texturing of extremely deformable surfaces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 45
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21929'
abstract:
- lang: eng
  text: 'The import of proteins into mitochondria poses fundamental mechanistic challenges:
    aggregation-prone precursor proteins must be maintained in aqueous compartments
    and threaded through narrow pores without becoming stuck or mislocalized. Recent
    evidence from mitochondrial protein import studies and other chaperone systems
    underscores the critical role of dynamics in balancing sufficiently tight binding,
    promiscuity, specificity, and release. Dynamic binding of client precursor proteins
    to import machinery components arises naturally from the avidity of their interactions.
    Conformational entropy enhances their stability, while the multivalent nature
    of these interactions ensures that client transfer to downstream insertases occurs
    without a substantial energy barrier. Here, we discuss this emerging paradigm
    of dynamic protein handling, using examples where dynamic structures have been
    resolved and highlight outstanding questions.'
acknowledgement: We gratefully acknowledge research funding by the Austrian Science
  Fund (FWF), projects 10.55776/PAT1647625 and 10.55776/I6223. We thank Prof. Long
  Li (Peking University) for providing structural models and EM density for the TOM
  and TIM23 complexes, used to generate part of Figure 3. Open Access funding provided
  by Institute of Science and Technology Austria.
article_number: e70630
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Jakob
  full_name: Schneider, Jakob
  id: 64368429-eb97-11eb-a6c2-c980b1f44415
  last_name: Schneider
- first_name: Undina
  full_name: Guillerm, Undina
  id: bb74f472-ae54-11eb-9835-bc9c22fb1183
  last_name: Guillerm
- first_name: Caroline
  full_name: Simoes Pereira, Caroline
  id: 87266c4a-96d2-11ef-be2c-fe5633233ec3
  last_name: Simoes Pereira
- first_name: Paul
  full_name: Schanda, Paul
  id: 7B541462-FAF6-11E9-A490-E8DFE5697425
  last_name: Schanda
  orcid: 0000-0002-9350-7606
citation:
  ama: Schneider J, Guillerm U, Simoes Pereira C, Schanda P. Dynamic disorder is crucial
    for mitochondrial protein import. <i>Protein Science</i>. 2026;35(6). doi:<a href="https://doi.org/10.1002/pro.70630">10.1002/pro.70630</a>
  apa: Schneider, J., Guillerm, U., Simoes Pereira, C., &#38; Schanda, P. (2026).
    Dynamic disorder is crucial for mitochondrial protein import. <i>Protein Science</i>.
    Wiley. <a href="https://doi.org/10.1002/pro.70630">https://doi.org/10.1002/pro.70630</a>
  chicago: Schneider, Jakob, Undina Guillerm, Caroline Simoes Pereira, and Paul Schanda.
    “Dynamic Disorder Is Crucial for Mitochondrial Protein Import.” <i>Protein Science</i>.
    Wiley, 2026. <a href="https://doi.org/10.1002/pro.70630">https://doi.org/10.1002/pro.70630</a>.
  ieee: J. Schneider, U. Guillerm, C. Simoes Pereira, and P. Schanda, “Dynamic disorder
    is crucial for mitochondrial protein import,” <i>Protein Science</i>, vol. 35,
    no. 6. Wiley, 2026.
  ista: Schneider J, Guillerm U, Simoes Pereira C, Schanda P. 2026. Dynamic disorder
    is crucial for mitochondrial protein import. Protein Science. 35(6), e70630.
  mla: Schneider, Jakob, et al. “Dynamic Disorder Is Crucial for Mitochondrial Protein
    Import.” <i>Protein Science</i>, vol. 35, no. 6, e70630, Wiley, 2026, doi:<a href="https://doi.org/10.1002/pro.70630">10.1002/pro.70630</a>.
  short: J. Schneider, U. Guillerm, C. Simoes Pereira, P. Schanda, Protein Science
    35 (2026).
corr_author: '1'
date_created: 2026-05-31T22:02:12Z
date_published: 2026-06-01T00:00:00Z
date_updated: 2026-06-02T07:26:34Z
day: '01'
ddc:
- '572'
department:
- _id: GradSch
- _id: PaSc
doi: 10.1002/pro.70630
external_id:
  pmid:
  - '42159315'
file:
- access_level: open_access
  checksum: e0163459a7238fdcc3fc5e17bedcce9a
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-02T07:23:12Z
  date_updated: 2026-06-02T07:23:12Z
  file_id: '21937'
  file_name: 2026_ProteinScience_Schneider.pdf
  file_size: 3897305
  relation: main_file
  success: 1
file_date_updated: 2026-06-02T07:23:12Z
has_accepted_license: '1'
intvolume: '        35'
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: bdb9578d-d553-11ed-ba76-ed5d39fce6f0
  grant_number: I06223
  name: Structure and mechanism of the mitochondrial MIM insertase
publication: Protein Science
publication_identifier:
  eissn:
  - 1469-896X
  issn:
  - 0961-8368
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dynamic disorder is crucial for mitochondrial protein import
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2026'
...
---
OA_place: publisher
_id: '21957'
abstract:
- lang: eng
  text: "This thesis investigates algorithmic certification and approximation methods
    for degenerate semidefinite programs (SDPs) and the singular roots of polynomial
    systems. In the first part, we present a hybrid symbolic-numeric algorithm for
    certifying the feasibility of weakly feasible, degenerate SDPs. By reformulating
    linear matrix inequalities (LMIs) into a structured polynomial system via facial
    reduction and incidence varieties, we guarantee the existence of an isolated exact
    solution. This algebraic reduction enables the certification of maximum-rank numerical
    approximations using methods from algebraic geometry.\r\n\r\nIn the second part,
    we address the severe ill-conditioning and loss of quadratic convergence that
    plague standard path-tracking methods near isolated singular roots. To overcome
    this, we propose tracking algorithms that achieve superlinear convergence without
    the computational bloat characteristic of classical deflation techniques. By modeling
    the solution path as a generalized fractional Puiseux series, our approach combines
    an explicitly derived algebraic predictor with a localized hyperplane desingularization
    phase during the corrector step. Furthermore, we introduce a continuous path-limit
    method and an extension of the geometric sequence rule to directly extract exact
    fractional exponents. This bypasses traditional heuristic trial-and-error methods
    and explicitly accommodates sparse series expansions. Numerical experiments confirm
    that our method significantly reduces the cumulative number of matrix inversions
    while achieving high-accuracy root approximations, even for heavily degenerate
    systems exhibiting higher coranks."
acknowledgement: 'Funding: Vienna Graduate School on Computational Optimization (FWF),
  grant DOI: 10.55776/W1260.'
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Jeferson
  full_name: Zapata, Jeferson
  id: 00223538-AF8F-11E9-A4C7-F729E6697425
  last_name: Zapata
citation:
  ama: 'Zapata J. Overcoming degeneracy and singularity : Techniques for semidefinite
    programs and homotopy continuation endgames. 2026. doi:<a href="https://doi.org/10.15479/AT-ISTA-21957">10.15479/AT-ISTA-21957</a>'
  apa: 'Zapata, J. (2026). <i>Overcoming degeneracy and singularity : Techniques for
    semidefinite programs and homotopy continuation endgames</i>. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21957">https://doi.org/10.15479/AT-ISTA-21957</a>'
  chicago: 'Zapata, Jeferson. “Overcoming Degeneracy and Singularity : Techniques
    for Semidefinite Programs and Homotopy Continuation Endgames.” Institute of Science
    and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21957">https://doi.org/10.15479/AT-ISTA-21957</a>.'
  ieee: 'J. Zapata, “Overcoming degeneracy and singularity : Techniques for semidefinite
    programs and homotopy continuation endgames,” Institute of Science and Technology
    Austria, 2026.'
  ista: 'Zapata J. 2026. Overcoming degeneracy and singularity : Techniques for semidefinite
    programs and homotopy continuation endgames. Institute of Science and Technology
    Austria.'
  mla: 'Zapata, Jeferson. <i>Overcoming Degeneracy and Singularity : Techniques for
    Semidefinite Programs and Homotopy Continuation Endgames</i>. Institute of Science
    and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21957">10.15479/AT-ISTA-21957</a>.'
  short: 'J. Zapata, Overcoming Degeneracy and Singularity : Techniques for Semidefinite
    Programs and Homotopy Continuation Endgames, Institute of Science and Technology
    Austria, 2026.'
corr_author: '1'
date_created: 2026-06-08T13:29:52Z
date_published: 2026-06-09T00:00:00Z
date_updated: 2026-06-12T10:37:00Z
day: '09'
ddc:
- '500'
degree_awarded: PhD
department:
- _id: GradSch
- _id: VlKo
doi: 10.15479/AT-ISTA-21957
file:
- access_level: closed
  checksum: b11a959e99d3dcf61040282b5c837141
  content_type: application/zip
  creator: jzapata
  date_created: 2026-06-08T13:20:02Z
  date_updated: 2026-06-08T13:20:02Z
  file_id: '21958'
  file_name: istaustriathesis_JZapata.zip
  file_size: 40811933
  relation: source_file
- access_level: open_access
  checksum: edf1e5899b2e31505cd1aa3fe8bd4b7f
  content_type: application/pdf
  creator: jzapata
  date_created: 2026-06-10T13:33:25Z
  date_updated: 2026-06-10T13:33:25Z
  file_id: '21992'
  file_name: 4_Final_Thesis_JZapata_REX.pdf
  file_size: 2207892
  relation: main_file
  success: 1
file_date_updated: 2026-06-10T13:33:25Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '89'
project:
- _id: 9B9290DE-BA93-11EA-9121-9846C619BF3A
  grant_number: W1260-N35
  name: Vienna Graduate School on Computational Optimization
publication_identifier:
  isbn:
  - 978-3-99078-079-4
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '21144'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
title: 'Overcoming degeneracy and singularity : Techniques for semidefinite programs
  and homotopy continuation endgames'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2026'
...
---
OA_place: repository
_id: '21960'
abstract:
- lang: eng
  text: "Solitons - localized wave packets that travel without spreading - play a
    central role in understanding transport and properties of nonlinear systems. In
    quantum many-body systems, however, such robust excitations are typically destroyed
    by thermalization. Here, we theoretically demonstrate the existence of solitonic
    excitations in high-energy states of Rydberg atom chains in the regime of strong
    nearest-neighbor Rydberg blockade. \r\nThese localized wave packets propagate
    directionally atop a special class of reviving initial states related to quantum
    many-body scars and are capable of carrying energy. Exhibiting long coherence
    times, these states constitute a form of non-ergodic quantum dynamics and can
    be efficiently implemented on Rydberg atom simulators. In this work, in addition
    to a phenomenological description of solitons, we identify their counterpart in
    a classical nonlinear dynamical system, demonstrate their potential use in quantum
    information transfer, and conjecture their relevance for anomalous energy transport
    reported in numerical studies of Rydberg atom arrays."
article_processing_charge: No
author:
- first_name: Aron
  full_name: Kerschbaumer, Aron
  id: ade85a9c-3200-11ee-973b-91c1eb240410
  last_name: Kerschbaumer
  orcid: 0009-0002-2370-8661
citation:
  ama: 'Kerschbaumer A. Research Data: “Quasi-solitons in Rydberg atom chains.” 2026.
    doi:<a href="https://doi.org/10.15479/AT-ISTA-21960">10.15479/AT-ISTA-21960</a>'
  apa: 'Kerschbaumer, A. (2026). Research Data: “Quasi-solitons in Rydberg atom chains.”
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT-ISTA-21960">https://doi.org/10.15479/AT-ISTA-21960</a>'
  chicago: 'Kerschbaumer, Aron. “Research Data: ‘Quasi-Solitons in Rydberg Atom Chains.’”
    Institute of Science and Technology Austria, 2026. <a href="https://doi.org/10.15479/AT-ISTA-21960">https://doi.org/10.15479/AT-ISTA-21960</a>.'
  ieee: 'A. Kerschbaumer, “Research Data: ‘Quasi-solitons in Rydberg atom chains.’”
    Institute of Science and Technology Austria, 2026.'
  ista: 'Kerschbaumer A. 2026. Research Data: ‘Quasi-solitons in Rydberg atom chains’,
    Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT-ISTA-21960">10.15479/AT-ISTA-21960</a>.'
  mla: 'Kerschbaumer, Aron. <i>Research Data: “Quasi-Solitons in Rydberg Atom Chains.”</i>
    Institute of Science and Technology Austria, 2026, doi:<a href="https://doi.org/10.15479/AT-ISTA-21960">10.15479/AT-ISTA-21960</a>.'
  short: A. Kerschbaumer, (2026).
contributor:
- contributor_type: contact_person
  first_name: Aron
  id: ade85a9c-3200-11ee-973b-91c1eb240410
  last_name: Kerschbaumer
  orcid: 0009-0002-2370-8661
- contributor_type: supervisor
  first_name: Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
- contributor_type: researcher
  first_name: Jean-Yves Marc
  id: 6c292945-a610-11ed-9eec-c3be1ad62a80
  last_name: Desaules
  orcid: 0000-0002-3749-6375
- contributor_type: researcher
  first_name: Marko
  last_name: Ljubotina
corr_author: '1'
date_created: 2026-06-09T07:17:50Z
date_published: 2026-06-16T00:00:00Z
date_updated: 2026-06-16T08:00:38Z
day: '16'
department:
- _id: GradSch
- _id: MaSe
doi: 10.15479/AT-ISTA-21960
ec_funded: 1
file:
- access_level: open_access
  checksum: 133269a105e996c6c44fdd56128259c7
  content_type: text/plain
  creator: akerschb
  date_created: 2026-06-15T22:01:57Z
  date_updated: 2026-06-15T22:01:57Z
  file_id: '22010'
  file_name: README.txt
  file_size: 1940
  relation: main_file
  success: 1
- access_level: open_access
  checksum: 759f9649c3919f4c4ad37a1d104ea32a
  content_type: application/zip
  creator: akerschb
  date_created: 2026-06-15T22:02:07Z
  date_updated: 2026-06-15T22:02:07Z
  file_id: '22011'
  file_name: Soliton_Data.zip
  file_size: 13259747
  relation: main_file
  success: 1
file_date_updated: 2026-06-15T22:02:07Z
has_accepted_license: '1'
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publisher: Institute of Science and Technology Austria
status: public
title: 'Research Data: "Quasi-solitons in Rydberg atom chains"'
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: research_data
user_id: 68b8ca59-c5b3-11ee-8790-cd641c68093d
year: '2026'
...
---
OA_place: repository
OA_type: green
_id: '21963'
abstract:
- lang: eng
  text: The cerebral cortex consists of immense numbers of neuronal and glial cell-types
    derived from radial glial progenitor (RGP) cells. How RGPs generate appropriate
    quantities of distinct cortical cell-types to safeguard a brain of correct size,
    is not well understood. However, genetic aberration in human, including mutations
    in PTEN, lead to cortical malformation such as macrocephaly, albeit with unknown
    etiology. Here we utilized Mosaic Analysis with Double Markers (MADM)-based clonal
    analysis and single cell phenotyping to decipher the role of Pten in neurogenic
    and gliogenic RGP lineage progression during cortical ontogeny. While neurogenic
    RGP lineage progression and projection neuron production was moderately altered
    in the absence of Pten, cortical astrocyte production was drastically increased.
    Through genetic epistasis experiments we show that the loss of Pten uncouples
    astrocyte generation from essential growth factor signaling hubs, funneling into
    MAPK. Collectively, our results suggest that Pten regulates RGP lineage progression
    with distinct sequential functions in cortical projection neurogenesis and astrocyte
    production to ensure the emergence of a correctly-sized cerebral cortex.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: PreCl
acknowledgement: "We thank Kay-Uwe Wagner (Wayne State University) for generously
  sharing Jak1/2–flox mouse lines; A.\r\nSommer (VBCF GmbH, NGS Unit) for technical
  support; N. Kim, V. Mick, S. Schnabl, S. Gobeil, and L.\r\nAndersen for technical
  assistance; all members of the Hippenmeyer lab for discussion and B. Novitch for\r\ncomments
  on earlier versions of the manuscript. This research was supported by the Scientific
  Service Units\r\n(SSU) of IST Austria through resources provided by the Imaging
  and Optics Facility (IOF), Lab Support-\r\n(LSF) and Preclinical Facilities (PCF).
  O.A.M received support from the Austrian Academy of Sciences\r\nÖAW (DOC 186584),
  and N.A. from FWF Elise Richter Program (Grant V1041T). This work was also\r\nsupported
  by IST Austria institutional funds; FWF SFB F78 (Neuro Stem Modulation) to S.H.,
  and the\r\nEuropean Research Council (ERC) under the European Union’s Horizon 2020
  research and innovation\r\nprogramme (grant agreement No 725780 LinPro) to S.H."
article_processing_charge: No
author:
- first_name: Osvaldo
  full_name: Miranda, Osvaldo
  id: 862A3C56-A8BF-11E9-B4FA-D9E3E5697425
  last_name: Miranda
  orcid: 0000-0001-6618-6889
- first_name: Ximena
  full_name: Contreras, Ximena
  id: 475990FE-F248-11E8-B48F-1D18A9856A87
  last_name: Contreras
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Amarbayasgalan
  full_name: Davaatseren, Amarbayasgalan
  id: 70ADC922-B424-11E9-99E3-BA18E6697425
  last_name: Davaatseren
- first_name: Nicole
  full_name: Amberg, Nicole
  id: 4CD6AAC6-F248-11E8-B48F-1D18A9856A87
  last_name: Amberg
  orcid: 0000-0002-3183-8207
- first_name: Carmen
  full_name: Streicher, Carmen
  id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
  last_name: Streicher
- first_name: Ana
  full_name: Villalba Requena, Ana
  id: 68cb85a0-39f7-11eb-9559-9aaab4f6a247
  last_name: Villalba Requena
  orcid: 0000-0002-5615-5277
- first_name: Anna-Magdalena
  full_name: Heger, Anna-Magdalena
  id: 4B76FFD2-F248-11E8-B48F-1D18A9856A87
  last_name: Heger
- first_name: Corentine
  full_name: Marie, Corentine
  last_name: Marie
- first_name: Bassem A.
  full_name: Hassan, Bassem A.
  last_name: Hassan
- first_name: Thomas
  full_name: Rülicke, Thomas
  last_name: Rülicke
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Miranda O, Contreras X, Pauler F, et al. Pten orchestrates neurogenic radial
    glia lineage progression and tunes neocortical astrocyte production. <i>bioRxiv</i>.
    doi:<a href="https://doi.org/10.64898/2026.05.01.722191">10.64898/2026.05.01.722191</a>
  apa: Miranda, O., Contreras, X., Pauler, F., Davaatseren, A., Amberg, N., Streicher,
    C., … Hippenmeyer, S. (n.d.). Pten orchestrates neurogenic radial glia lineage
    progression and tunes neocortical astrocyte production. <i>bioRxiv</i>. <a href="https://doi.org/10.64898/2026.05.01.722191">https://doi.org/10.64898/2026.05.01.722191</a>
  chicago: Miranda, Osvaldo, Ximena Contreras, Florian Pauler, Amarbayasgalan Davaatseren,
    Nicole Amberg, Carmen Streicher, Ana Villalba Requena, et al. “Pten Orchestrates
    Neurogenic Radial Glia Lineage Progression and Tunes Neocortical Astrocyte Production.”
    <i>BioRxiv</i>, n.d. <a href="https://doi.org/10.64898/2026.05.01.722191">https://doi.org/10.64898/2026.05.01.722191</a>.
  ieee: O. Miranda <i>et al.</i>, “Pten orchestrates neurogenic radial glia lineage
    progression and tunes neocortical astrocyte production,” <i>bioRxiv</i>. .
  ista: Miranda O, Contreras X, Pauler F, Davaatseren A, Amberg N, Streicher C, Villalba
    Requena A, Heger A-M, Marie C, Hassan BA, Rülicke T, Hippenmeyer S. Pten orchestrates
    neurogenic radial glia lineage progression and tunes neocortical astrocyte production.
    bioRxiv, <a href="https://doi.org/10.64898/2026.05.01.722191">10.64898/2026.05.01.722191</a>.
  mla: Miranda, Osvaldo, et al. “Pten Orchestrates Neurogenic Radial Glia Lineage
    Progression and Tunes Neocortical Astrocyte Production.” <i>BioRxiv</i>, doi:<a
    href="https://doi.org/10.64898/2026.05.01.722191">10.64898/2026.05.01.722191</a>.
  short: O. Miranda, X. Contreras, F. Pauler, A. Davaatseren, N. Amberg, C. Streicher,
    A. Villalba Requena, A.-M. Heger, C. Marie, B.A. Hassan, T. Rülicke, S. Hippenmeyer,
    BioRxiv (n.d.).
corr_author: '1'
date_created: 2026-06-09T08:08:53Z
date_published: 2026-05-05T00:00:00Z
date_updated: 2026-06-16T08:57:20Z
day: '05'
ddc:
- '570'
department:
- _id: SiHi
- _id: PreCl
- _id: GradSch
doi: 10.64898/2026.05.01.722191
ec_funded: 1
has_accepted_license: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.64898/2026.05.01.722191
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F7805
  name: Stem Cell Modulation in Neural Development and Regeneration/ P05-Molecular
    Mechanisms of Neural Stem Cell Lineage Progression
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: bioRxiv
publication_status: submitted
status: public
title: Pten orchestrates neurogenic radial glia lineage progression and tunes neocortical
  astrocyte production
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21980'
abstract:
- lang: eng
  text: Despite significant progress in the field of molecular electronics over the
    last two decades, the quantitative prediction of metal-molecule-metal junction
    conductance remains a challenge. The standard computational framework combines
    density functional theory (DFT) with nonequilibrium Green’s functions (NEGF) using
    low-rung exchange-correlation functionals such as PBE, which overestimate the
    conductances. More advanced correction methods exist but require complex workflows
    and high computational cost, limiting their accessibility. Here, we introduce
    a physically motivated approach that approximates results obtained with high-rung
    functionals. Our method fits the PBE-calculated transmission to a Breit-Wigner
    form and subsequently refines the fit parameters using molecular orbital energies
    and metal densities of states computed for the isolated subsystems with high-rung
    functionals. This approach is applicable to a broad range of molecular junctions
    yielding conductance values in quantitative agreement with experiments. Our approach
    is simple, low-cost, and accurate, making it well-suited for routine and large-scale
    prediction of single-molecule junction conductance.
acknowledgement: This work was supported primarily by the Institute of Science and
  Technology Austria. L.V. was supported in part by the National Science Foundation
  (No. NSF-DMR 2241180). Z.-F.L. was supported by an NSF CAREER Award, No. DMR-2044552
  and an Alfred P. Sloan Research Fellowship, No. FG-2024-21750.
article_processing_charge: Yes (via OA deal)
article_type: letter_note
author:
- first_name: Artem
  full_name: Gulyaev, Artem
  id: 83ed7901-7380-11f0-bf20-a0788d5e654d
  last_name: Gulyaev
- first_name: Jyotisman
  full_name: Hazarika, Jyotisman
  id: d87714c4-663d-11f0-bd06-caece19833e5
  last_name: Hazarika
  orcid: 0009-0007-2542-7878
- first_name: Zhen-Fei
  full_name: Liu, Zhen-Fei
  last_name: Liu
- first_name: Latha
  full_name: Venkataraman, Latha
  id: 9ebb78a5-cc0d-11ee-8322-fae086a32caf
  last_name: Venkataraman
  orcid: 0000-0002-6957-6089
citation:
  ama: Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. A computationally efficient
    and accurate method for predicting conductance of single-molecule junctions. <i>Nano
    Letters</i>. 2026;26(22):7429–7434. doi:<a href="https://doi.org/10.1021/acs.nanolett.6c01462">10.1021/acs.nanolett.6c01462</a>
  apa: Gulyaev, A., Hazarika, J., Liu, Z.-F., &#38; Venkataraman, L. (2026). A computationally
    efficient and accurate method for predicting conductance of single-molecule junctions.
    <i>Nano Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.nanolett.6c01462">https://doi.org/10.1021/acs.nanolett.6c01462</a>
  chicago: Gulyaev, Artem, Jyotisman Hazarika, Zhen-Fei Liu, and Latha Venkataraman.
    “A Computationally Efficient and Accurate Method for Predicting Conductance of
    Single-Molecule Junctions.” <i>Nano Letters</i>. American Chemical Society, 2026.
    <a href="https://doi.org/10.1021/acs.nanolett.6c01462">https://doi.org/10.1021/acs.nanolett.6c01462</a>.
  ieee: A. Gulyaev, J. Hazarika, Z.-F. Liu, and L. Venkataraman, “A computationally
    efficient and accurate method for predicting conductance of single-molecule junctions,”
    <i>Nano Letters</i>, vol. 26, no. 22. American Chemical Society, pp. 7429–7434,
    2026.
  ista: Gulyaev A, Hazarika J, Liu Z-F, Venkataraman L. 2026. A computationally efficient
    and accurate method for predicting conductance of single-molecule junctions. Nano
    Letters. 26(22), 7429–7434.
  mla: Gulyaev, Artem, et al. “A Computationally Efficient and Accurate Method for
    Predicting Conductance of Single-Molecule Junctions.” <i>Nano Letters</i>, vol.
    26, no. 22, American Chemical Society, 2026, pp. 7429–7434, doi:<a href="https://doi.org/10.1021/acs.nanolett.6c01462">10.1021/acs.nanolett.6c01462</a>.
  short: A. Gulyaev, J. Hazarika, Z.-F. Liu, L. Venkataraman, Nano Letters 26 (2026)
    7429–7434.
corr_author: '1'
date_created: 2026-06-10T07:27:19Z
date_published: 2026-06-01T00:00:00Z
date_updated: 2026-06-16T09:13:30Z
day: '01'
ddc:
- '540'
department:
- _id: LaVe
- _id: GradSch
doi: 10.1021/acs.nanolett.6c01462
external_id:
  pmid:
  - '42223342'
file:
- access_level: open_access
  checksum: 897551374cac28e0db26dcb0b676b8e7
  content_type: application/pdf
  creator: dernst
  date_created: 2026-06-16T09:11:35Z
  date_updated: 2026-06-16T09:11:35Z
  file_id: '22013'
  file_name: 2026_NanoLetters_Gulyaev.pdf
  file_size: 3362800
  relation: main_file
  success: 1
file_date_updated: 2026-06-16T09:11:35Z
has_accepted_license: '1'
intvolume: '        26'
issue: '22'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 7429–7434
pmid: 1
publication: Nano Letters
publication_identifier:
  eissn:
  - 1530-6992
  issn:
  - 1530-6984
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: A computationally efficient and accurate method for predicting conductance
  of single-molecule junctions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2026'
...
---
OA_place: publisher
OA_type: hybrid
PlanS_conform: '1'
_id: '21981'
abstract:
- lang: eng
  text: For Hamiltonian actions of semidirect products G = FxH, we study 2-cocycles
    arising from residual Hamiltonian actions of F on Hamiltonian reductions for H.
    The motivation comes from the study of Teichmüller spaces for surfaces with boundary,
    which carry Hamiltonian actions of the Virasoro algebra. In this paper, we give
    a general setup for the problem, and we suggest an easier way to obtain the Gelfand-Fuchs
    2-cocycles for Hamiltonian actions on Teichmüller spaces.
article_number: '105878'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Viacheslav
  full_name: Goncharov, Viacheslav
  id: 8a0e2993-7114-11f0-b60e-f50e633649d8
  last_name: Goncharov
citation:
  ama: Goncharov V. An easier way to compute 2-cocycles coming from a reduction for
    semidirect products. <i>Journal of Geometry and Physics</i>. 2026;227. doi:<a
    href="https://doi.org/10.1016/j.geomphys.2026.105878">10.1016/j.geomphys.2026.105878</a>
  apa: Goncharov, V. (2026). An easier way to compute 2-cocycles coming from a reduction
    for semidirect products. <i>Journal of Geometry and Physics</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.geomphys.2026.105878">https://doi.org/10.1016/j.geomphys.2026.105878</a>
  chicago: Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from
    a Reduction for Semidirect Products.” <i>Journal of Geometry and Physics</i>.
    Elsevier, 2026. <a href="https://doi.org/10.1016/j.geomphys.2026.105878">https://doi.org/10.1016/j.geomphys.2026.105878</a>.
  ieee: V. Goncharov, “An easier way to compute 2-cocycles coming from a reduction
    for semidirect products,” <i>Journal of Geometry and Physics</i>, vol. 227. Elsevier,
    2026.
  ista: Goncharov V. 2026. An easier way to compute 2-cocycles coming from a reduction
    for semidirect products. Journal of Geometry and Physics. 227, 105878.
  mla: Goncharov, Viacheslav. “An Easier Way to Compute 2-Cocycles Coming from a Reduction
    for Semidirect Products.” <i>Journal of Geometry and Physics</i>, vol. 227, 105878,
    Elsevier, 2026, doi:<a href="https://doi.org/10.1016/j.geomphys.2026.105878">10.1016/j.geomphys.2026.105878</a>.
  short: V. Goncharov, Journal of Geometry and Physics 227 (2026).
corr_author: '1'
date_created: 2026-06-10T07:29:13Z
date_published: 2026-05-21T00:00:00Z
date_updated: 2026-06-16T09:23:39Z
day: '21'
ddc:
- '000'
department:
- _id: GradSch
doi: 10.1016/j.geomphys.2026.105878
external_id:
  arxiv:
  - '2509.16169'
has_accepted_license: '1'
intvolume: '       227'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.geomphys.2026.105878
month: '05'
oa: 1
oa_version: Published Version
publication: Journal of Geometry and Physics
publication_identifier:
  eissn:
  - 1879-1662
  issn:
  - 0393-0440
publication_status: epub_ahead
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: An easier way to compute 2-cocycles coming from a reduction for semidirect
  products
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 227
year: '2026'
...
