LGI1 antibody-induced pathophysiology in synapses

Project Period: 2020-01-01 – 2022-12-31
Funder: Austrian Science Fund
Acronym
SYNABS
Principal Investigator
Department(s)
Shigemoto Group
Grant Number
I04638
Grant DOI
10.55776/I4638
Funder
Austrian Science Fund
Funder Schema
FWF-DFG-FG
Funder Registry
10.13039/501100002428

3 Publications

2026 | Published | Journal Article | IST-REx-ID: 22615 | OA | PlanS
Muscle regeneration failure may lead to clinical features of myopathy in anti-IgLON5 disease
Crijnen YS, Endmayr V, Franken SC, Van Der Beek NAME, Louter M, Ströbel T, Gelpi E, Koneczny I, Shigemoto R, Lewerenz J, Högl B, Wanschitz JV, Hofstadt-Van Oy UH, Van Steenhoven RW, Nagtzaam MMP, Kerstens J, Brenner J, Bastiaansen AEM, Verdijk RM, Van Den Bosch TPP, Schreurs M, Veenbergen S, Verbeek MM, Roelen DL, Guasp M, Sillevis Smitt PAE, Sabater L, De Vries JM, Höftberger R, Titulaer MJ. 2026. Muscle regeneration failure may lead to clinical features of myopathy in anti-IgLON5 disease. Neurology, Neuroimmunology & Neuroinflammation. 13(5), e200525.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
2024 | Published | Journal Article | IST-REx-ID: 17457 | OA
LGI1 autoantibodies enhance synaptic transmission by presynaptic Kv1 loss and increased action potential broadening
A. Ritzau-Jost, F. Gsell, J. Sell, S. Sachs, J.-C. Montanaro-Punzengruber, T. Kirmann, S. Maaß, S.R. Irani, C. Werner, C. Geis, M. Sauer, R. Shigemoto, S. Hallermann, Neurology, Neuroimmunology & Neuroinflammation 11 (2024) e200284.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2022 | Published | Journal Article | IST-REx-ID: 10890 | OA
The number and distinct clustering patterns of voltage-gated Calcium channels in nerve terminals
K. Eguchi, J.-C. Montanaro-Punzengruber, E. Le Monnier, R. Shigemoto, Frontiers in Neuroanatomy 16 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 

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