Can evolution minimize spurious signaling crosstalk to reach optimal performance?

Project Period: 2018-12-01 – 2021-11-30
Externally Funded
Principal Investigator
Gašper Tkačik
Department(s)
Tkacik Group
Grant Number
RGP0034/2018
Funding Organisation
HFSP

4 Publications

2024 | Thesis | IST-REx-ID: 15020 | OA
Genetic information and biological optimization
M. Hledik, Genetic Information and Biological Optimization, Institute of Science and Technology Austria, 2024.
[Published Version] View | Files available | DOI
 
2022 | Journal Article | IST-REx-ID: 12081 | OA
Accumulation and maintenance of information in evolution
M. Hledik, N.H. Barton, G. Tkačik, Proceedings of the National Academy of Sciences 119 (2022).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2020 | Journal Article | IST-REx-ID: 9000 | OA
Nonequilibrium models of optimal enhancer function
R. Grah, B. Zoller, G. Tkačik, PNAS 117 (2020) 31614–31622.
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
2020 | Preprint | IST-REx-ID: 7675 | OA
Normative models of enhancer function
R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
[Preprint] View | Files available | DOI | Download Preprint (ext.)