Structural conservation and diversity in retroviral capsid
Project Period: 2018-10-01 – 2021-09-30
Funder:
Austrian Science Fund
Principal Investigator
Schur, Florian
Department(s)
Grant Number
P31445
Grant DOI
Funder
Austrian Science Fund
Funder Schema
FWF-StA
Funder Registry
9 Publications
2024 | Published | Thesis | IST-REx-ID: 18766 |

Elucidating the structural determinants of the poxvirus core using multi-modal cryo-EM
J. Datler, Elucidating the Structural Determinants of the Poxvirus Core Using Multi-Modal Cryo-EM, Institute of Science and Technology Austria, 2024.
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J. Datler, Elucidating the Structural Determinants of the Poxvirus Core Using Multi-Modal Cryo-EM, Institute of Science and Technology Austria, 2024.
2024 | Published | Journal Article | IST-REx-ID: 14979 |

Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores
J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural & Molecular Biology 31 (2024) 1114–1123.
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J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural & Molecular Biology 31 (2024) 1114–1123.
2024 | Epub ahead of print | Journal Article | IST-REx-ID: 17884 |

Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice
M. Obr, M. Percipalle, D. Chernikova, H. Yang, A. Thader, G. Pinke, D. Porley Esteves, L.M. Mansky, R.A. Dick, F.K. Schur, Nature Structural & Molecular Biology (2024).
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M. Obr, M. Percipalle, D. Chernikova, H. Yang, A. Thader, G. Pinke, D. Porley Esteves, L.M. Mansky, R.A. Dick, F.K. Schur, Nature Structural & Molecular Biology (2024).
2023 | Published | Journal Article | IST-REx-ID: 14255 |

The phenuivirus Toscana virus makes an atypical use of vacuolar acidity to enter host cells
J. Koch, Q. Xin, M. Obr, A. Schäfer, N. Rolfs, H.A. Anagho, A. Kudulyte, L. Woltereck, S. Kummer, J. Campos, Z.M. Uckeley, L. Bell-Sakyi, H.G. Kräusslich, F.K. Schur, C. Acuna, P.Y. Lozach, PLoS Pathogens 19 (2023).
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J. Koch, Q. Xin, M. Obr, A. Schäfer, N. Rolfs, H.A. Anagho, A. Kudulyte, L. Woltereck, S. Kummer, J. Campos, Z.M. Uckeley, L. Bell-Sakyi, H.G. Kräusslich, F.K. Schur, C. Acuna, P.Y. Lozach, PLoS Pathogens 19 (2023).
2022 | Published | Journal Article | IST-REx-ID: 10639 |

The Orthobunyavirus Germiston enters host cells from late endosomes
S. Windhaber, Q. Xin, Z.M. Uckeley, J. Koch, M. Obr, C. Garnier, C. Luengo-Guyonnot, M. Duboeuf, F.K. Schur, P.-Y. Lozach, Journal of Virology 96 (2022).
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S. Windhaber, Q. Xin, Z.M. Uckeley, J. Koch, M. Obr, C. Garnier, C. Luengo-Guyonnot, M. Duboeuf, F.K. Schur, P.-Y. Lozach, Journal of Virology 96 (2022).
2022 | Published | Journal Article | IST-REx-ID: 11155 |

Exploring high-resolution cryo-ET and subtomogram averaging capabilities of contemporary DEDs
M. Obr, W.J.H. Hagen, R.A. Dick, L. Yu, A. Kotecha, F.K. Schur, Journal of Structural Biology 214 (2022).
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M. Obr, W.J.H. Hagen, R.A. Dick, L. Yu, A. Kotecha, F.K. Schur, Journal of Structural Biology 214 (2022).
2021 | Published | Journal Article | IST-REx-ID: 10103 |

A structural perspective of the role of IP6 in immature and mature retroviral assembly
M. Obr, F.K. Schur, R.A. Dick, Viruses 13 (2021).
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M. Obr, F.K. Schur, R.A. Dick, Viruses 13 (2021).
2021 | Published | Journal Article | IST-REx-ID: 9431 |

Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).
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M. Obr, C.L. Ricana, N. Nikulin, J.-P.R. Feathers, M. Klanschnig, A. Thader, M.C. Johnson, V.M. Vogt, F.K. Schur, R.A. Dick, Nature Communications 12 (2021).
2020 | Published | Journal Article | IST-REx-ID: 7464 |

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly
R.A. Dick, C. Xu, D.R. Morado, V. Kravchuk, C.L. Ricana, T.D. Lyddon, A.M. Broad, J.R. Feathers, M.C. Johnson, V.M. Vogt, J.R. Perilla, J.A.G. Briggs, F.K. Schur, PLOS Pathogens 16 (2020).
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R.A. Dick, C. Xu, D.R. Morado, V. Kravchuk, C.L. Ricana, T.D. Lyddon, A.M. Broad, J.R. Feathers, M.C. Johnson, V.M. Vogt, J.R. Perilla, J.A.G. Briggs, F.K. Schur, PLOS Pathogens 16 (2020).