---
res:
  bibo_abstract:
  - Growth regulation tailors development in plants to their environment. A prominent
    example of this is the response to gravity, in which shoots bend up and roots
    bend down1. This paradox is based on opposite effects of the phytohormone auxin,
    which promotes cell expansion in shoots while inhibiting it in roots via a yet
    unknown cellular mechanism2. Here, by combining microfluidics, live imaging, genetic
    engineering and phosphoproteomics in Arabidopsis thaliana, we advance understanding
    of how auxin inhibits root growth. We show that auxin activates two distinct,
    antagonistically acting signalling pathways that converge on rapid regulation
    of apoplastic pH, a causative determinant of growth. Cell surface-based TRANSMEMBRANE
    KINASE1 (TMK1) interacts with and mediates phosphorylation and activation of plasma
    membrane H+-ATPases for apoplast acidification, while intracellular canonical
    auxin signalling promotes net cellular H+ influx, causing apoplast alkalinization.
    Simultaneous activation of these two counteracting mechanisms poises roots for
    rapid, fine-tuned growth modulation in navigating complex soil environments.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Lanxin
      foaf_name: Li, Lanxin
      foaf_surname: Li
      foaf_workInfoHomepage: http://www.librecat.org/personId=367EF8FA-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-5607-272X
  - foaf_Person:
      foaf_givenName: Inge
      foaf_name: Verstraeten, Inge
      foaf_surname: Verstraeten
      foaf_workInfoHomepage: http://www.librecat.org/personId=362BF7FE-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-7241-2328
  - foaf_Person:
      foaf_givenName: Mark
      foaf_name: Roosjen, Mark
      foaf_surname: Roosjen
  - foaf_Person:
      foaf_givenName: Koji
      foaf_name: Takahashi, Koji
      foaf_surname: Takahashi
  - foaf_Person:
      foaf_givenName: Lesia
      foaf_name: Rodriguez Solovey, Lesia
      foaf_surname: Rodriguez Solovey
      foaf_workInfoHomepage: http://www.librecat.org/personId=3922B506-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-7244-7237
  - foaf_Person:
      foaf_givenName: Jack
      foaf_name: Merrin, Jack
      foaf_surname: Merrin
      foaf_workInfoHomepage: http://www.librecat.org/personId=4515C308-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-5145-4609
  - foaf_Person:
      foaf_givenName: Jian
      foaf_name: Chen, Jian
      foaf_surname: Chen
  - foaf_Person:
      foaf_givenName: Lana
      foaf_name: Shabala, Lana
      foaf_surname: Shabala
  - foaf_Person:
      foaf_givenName: Wouter
      foaf_name: Smet, Wouter
      foaf_surname: Smet
  - foaf_Person:
      foaf_givenName: Hong
      foaf_name: Ren, Hong
      foaf_surname: Ren
  - foaf_Person:
      foaf_givenName: Steffen
      foaf_name: Vanneste, Steffen
      foaf_surname: Vanneste
  - foaf_Person:
      foaf_givenName: Sergey
      foaf_name: Shabala, Sergey
      foaf_surname: Shabala
  - foaf_Person:
      foaf_givenName: Bert
      foaf_name: De Rybel, Bert
      foaf_surname: De Rybel
  - foaf_Person:
      foaf_givenName: Dolf
      foaf_name: Weijers, Dolf
      foaf_surname: Weijers
  - foaf_Person:
      foaf_givenName: Toshinori
      foaf_name: Kinoshita, Toshinori
      foaf_surname: Kinoshita
  - foaf_Person:
      foaf_givenName: William M.
      foaf_name: Gray, William M.
      foaf_surname: Gray
  - foaf_Person:
      foaf_givenName: Jiří
      foaf_name: Friml, Jiří
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  bibo_doi: 10.1038/s41586-021-04037-6
  bibo_issue: '7884'
  bibo_volume: 599
  dct_date: 2021^xs_gYear
  dct_identifier:
  - UT:000713338100006
  dct_isPartOf:
  - http://id.crossref.org/issn/0028-0836
  - http://id.crossref.org/issn/1476-4687
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_subject:
  - Multidisciplinary
  dct_title: Cell surface and intracellular auxin signalling for H<sup>+</sup> fluxes
    in root growth@
  fabio_hasPubmedId: '34707283'
...