{"pmid":1,"abstract":[{"lang":"eng","text":"We study the effects of osmotic shocks on lipid vesicles via coarse-grained molecular dynamics simulations by explicitly considering the solute in the system. We find that depending on their nature (hypo- or hypertonic) such shocks can lead to bursting events or engulfing of external material into inner compartments, among other morphology transformations. We characterize the dynamics of these processes and observe a separation of time scales between the osmotic shock absorption and the shape relaxation. Our work consequently provides an insight into the dynamics of compartmentalization in vesicular systems as a result of osmotic shocks, which can be of interest in the context of early proto-cell development and proto-cell compartmentalisation."}],"oa":1,"oa_version":"Published Version","date_published":"2021-02-16T00:00:00Z","type":"journal_article","tmp":{"short":"CC BY-NC (3.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/3.0/legalcode","image":"/images/cc_by_nc.png","name":"Creative Commons Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)"},"publisher":"Royal Society of Chemistry","article_type":"original","issue":"14","page":"3798-3806","day":"16","intvolume":"        17","publication_identifier":{"eissn":["1744-6848"],"issn":["1744-683X"]},"language":[{"iso":"eng"}],"date_created":"2021-11-25T16:06:42Z","title":"Modelling the dynamics of vesicle reshaping and scission under osmotic shocks","article_processing_charge":"No","related_material":{"link":[{"relation":"earlier_version","url":"https://www.biorxiv.org/content/10.1101/2020.11.16.384602v2"}]},"status":"public","acknowledgement":"We acknowledge support from the Royal Society (C. V. C. and A. Sˇ.), the Medical Research Council (C. V. C. and A. Sˇ.), and the European Research Council (Starting grant ‘‘NEPA’’ 802960 to A. Sˇ.). We thank Johannes Krausser and Ivan Palaia for fruitful discussions.","license":"https://creativecommons.org/licenses/by-nc/3.0/","publication_status":"published","main_file_link":[{"open_access":"1","url":"https://pubs.rsc.org/en/content/articlehtml/2021/sm/d0sm02012e"}],"scopus_import":"1","keyword":["condensed matter physics","general chemistry"],"extern":"1","volume":17,"citation":{"mla":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>, vol. 17, no. 14, Royal Society of Chemistry, 2021, pp. 3798–806, doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>.","ista":"Vanhille-Campos C, Šarić A. 2021. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. Soft Matter. 17(14), 3798–3806.","ieee":"C. Vanhille-Campos and A. Šarić, “Modelling the dynamics of vesicle reshaping and scission under osmotic shocks,” <i>Soft Matter</i>, vol. 17, no. 14. Royal Society of Chemistry, pp. 3798–3806, 2021.","short":"C. Vanhille-Campos, A. Šarić, Soft Matter 17 (2021) 3798–3806.","apa":"Vanhille-Campos, C., &#38; Šarić, A. (2021). Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. Royal Society of Chemistry. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>","ama":"Vanhille-Campos C, Šarić A. Modelling the dynamics of vesicle reshaping and scission under osmotic shocks. <i>Soft Matter</i>. 2021;17(14):3798-3806. doi:<a href=\"https://doi.org/10.1039/d0sm02012e\">10.1039/d0sm02012e</a>","chicago":"Vanhille-Campos, Christian, and Anđela Šarić. “Modelling the Dynamics of Vesicle Reshaping and Scission under Osmotic Shocks.” <i>Soft Matter</i>. Royal Society of Chemistry, 2021. <a href=\"https://doi.org/10.1039/d0sm02012e\">https://doi.org/10.1039/d0sm02012e</a>."},"publication":"Soft Matter","month":"02","_id":"10339","year":"2021","doi":"10.1039/d0sm02012e","quality_controlled":"1","author":[{"full_name":"Vanhille-Campos, Christian","first_name":"Christian","last_name":"Vanhille-Campos"},{"full_name":"Šarić, Anđela","last_name":"Šarić","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","orcid":"0000-0002-7854-2139","first_name":"Anđela"}],"external_id":{"pmid":["33629089"]},"date_updated":"2021-11-30T08:20:09Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9"}