---
_id: '10411'
abstract:
- lang: eng
  text: The phytohormone auxin is the major growth regulator governing tropic responses
    including gravitropism. Auxin build-up at the lower side of stimulated shoots
    promotes cell expansion, whereas in roots it inhibits growth, leading to upward
    shoot bending and downward root bending, respectively. Yet it remains an enigma
    how the same signal can trigger such opposite cellular responses. In this review,
    we discuss several recent unexpected insights into the mechanisms underlying auxin
    regulation of growth, challenging several existing models. We focus on the divergent
    mechanisms of apoplastic pH regulation in shoots and roots revisiting the classical
    Acid Growth Theory and discuss coordinated involvement of multiple auxin signaling
    pathways. From this emerges a more comprehensive, updated picture how auxin regulates
    growth.
acknowledgement: The authors thank Alexandra Mally for editing the text. This work
  was supported by the Austrian Science Fund (FWF) I 3630-B25 to Jiří Friml and the
  DOC Fellowship of the Austrian Academy of Sciences to Lanxin Li. All figures were
  created with BioRender.com.
article_processing_charge: No
article_type: original
author:
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Li L, Gallei MC, Friml J. Bending to auxin: Fast acid growth for tropisms.
    <i>Trends in Plant Science</i>. 2022;27(5):440-449. doi:<a href="https://doi.org/10.1016/j.tplants.2021.11.006">10.1016/j.tplants.2021.11.006</a>'
  apa: 'Li, L., Gallei, M. C., &#38; Friml, J. (2022). Bending to auxin: Fast acid
    growth for tropisms. <i>Trends in Plant Science</i>. Cell Press. <a href="https://doi.org/10.1016/j.tplants.2021.11.006">https://doi.org/10.1016/j.tplants.2021.11.006</a>'
  chicago: 'Li, Lanxin, Michelle C Gallei, and Jiří Friml. “Bending to Auxin: Fast
    Acid Growth for Tropisms.” <i>Trends in Plant Science</i>. Cell Press, 2022. <a
    href="https://doi.org/10.1016/j.tplants.2021.11.006">https://doi.org/10.1016/j.tplants.2021.11.006</a>.'
  ieee: 'L. Li, M. C. Gallei, and J. Friml, “Bending to auxin: Fast acid growth for
    tropisms,” <i>Trends in Plant Science</i>, vol. 27, no. 5. Cell Press, pp. 440–449,
    2022.'
  ista: 'Li L, Gallei MC, Friml J. 2022. Bending to auxin: Fast acid growth for tropisms.
    Trends in Plant Science. 27(5), 440–449.'
  mla: 'Li, Lanxin, et al. “Bending to Auxin: Fast Acid Growth for Tropisms.” <i>Trends
    in Plant Science</i>, vol. 27, no. 5, Cell Press, 2022, pp. 440–49, doi:<a href="https://doi.org/10.1016/j.tplants.2021.11.006">10.1016/j.tplants.2021.11.006</a>.'
  short: L. Li, M.C. Gallei, J. Friml, Trends in Plant Science 27 (2022) 440–449.
corr_author: '1'
date_created: 2021-12-05T23:01:43Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2026-04-07T14:18:57Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.tplants.2021.11.006
external_id:
  isi:
  - '000793707900005'
  pmid:
  - '34848141'
file:
- access_level: open_access
  checksum: 3d94980ee1ff6bec100dd813f6a921a6
  content_type: application/pdf
  creator: amally
  date_created: 2023-11-02T17:00:03Z
  date_updated: 2023-11-02T17:00:03Z
  file_id: '14480'
  file_name: Li Plants 2021_accepted.pdf
  file_size: 805779
  relation: main_file
  success: 1
file_date_updated: 2023-11-02T17:00:03Z
has_accepted_license: '1'
intvolume: '        27'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 440-449
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 26B4D67E-B435-11E9-9278-68D0E5697425
  grant_number: '25351'
  name: 'A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated
    Rapid Growth Inhibition in Arabidopsis Root'
publication: Trends in Plant Science
publication_identifier:
  issn:
  - 1360-1385
publication_status: published
publisher: Cell Press
quality_controlled: '1'
related_material:
  record:
  - id: '11626'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'Bending to auxin: Fast acid growth for tropisms'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2022'
...