---
res:
  bibo_abstract:
  - Ribosomal defects perturb stem cell differentiation, causing diseases called ribosomopathies.
    How ribosome levels control stem cell differentiation is not fully known. Here,
    we discovered three RNA helicases are required for ribosome biogenesis and for
    Drosophila oogenesis. Loss of these helicases, which we named Aramis, Athos and
    Porthos, lead to aberrant stabilization of p53, cell cycle arrest and stalled
    GSC differentiation. Unexpectedly, Aramis is required for efficient translation
    of a cohort of mRNAs containing a 5’-Terminal-Oligo-Pyrimidine (TOP)-motif, including
    mRNAs that encode ribosomal proteins and a conserved p53 inhibitor, Novel Nucleolar
    protein 1 (Non1). The TOP-motif co-regulates the translation of growth-related
    mRNAs in mammals. As in mammals, the La-related protein co-regulates the translation
    of TOP-motif containing RNAs during Drosophila oogenesis. Thus, a previously unappreciated
    TOP-motif in Drosophila responds to reduced ribosome biogenesis to co-regulate
    the translation of ribosomal proteins and a p53 repressor, thus coupling ribosome
    biogenesis to GSC differentiation.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Elliot T.
      foaf_name: Martin, Elliot T.
      foaf_surname: Martin
  - foaf_Person:
      foaf_givenName: Patrick
      foaf_name: Blatt, Patrick
      foaf_surname: Blatt
  - foaf_Person:
      foaf_givenName: Elaine
      foaf_name: Ngyuen, Elaine
      foaf_surname: Ngyuen
  - foaf_Person:
      foaf_givenName: Roni
      foaf_name: Lahr, Roni
      foaf_surname: Lahr
  - foaf_Person:
      foaf_givenName: Sangeetha
      foaf_name: Selvam, Sangeetha
      foaf_surname: Selvam
  - foaf_Person:
      foaf_givenName: Hyun Ah M.
      foaf_name: Yoon, Hyun Ah M.
      foaf_surname: Yoon
  - foaf_Person:
      foaf_givenName: Tyler
      foaf_name: Pocchiari, Tyler
      foaf_surname: Pocchiari
  - foaf_Person:
      foaf_givenName: Shamsi
      foaf_name: Emtenani, Shamsi
      foaf_surname: Emtenani
      foaf_workInfoHomepage: http://www.librecat.org/personId=49D32318-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6981-6938
  - foaf_Person:
      foaf_givenName: Daria E
      foaf_name: Siekhaus, Daria E
      foaf_surname: Siekhaus
      foaf_workInfoHomepage: http://www.librecat.org/personId=3D224B9E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8323-8353
  - foaf_Person:
      foaf_givenName: Andrea
      foaf_name: Berman, Andrea
      foaf_surname: Berman
  - foaf_Person:
      foaf_givenName: Gabriele
      foaf_name: Fuchs, Gabriele
      foaf_surname: Fuchs
  - foaf_Person:
      foaf_givenName: Prashanth
      foaf_name: Rangan, Prashanth
      foaf_surname: Rangan
  bibo_doi: 10.1016/j.devcel.2022.03.005
  bibo_issue: '7'
  bibo_volume: 57
  dct_date: 2022^xs_gYear
  dct_identifier:
  - UT:000789021800005
  dct_isPartOf:
  - http://id.crossref.org/issn/1534-5807
  - http://id.crossref.org/issn/1878-1551
  dct_language: eng
  dct_publisher: Elsevier@
  dct_title: A translation control module coordinates germline stem cell differentiation
    with ribosome biogenesis during Drosophila oogenesis@
  fabio_hasPubmedId: '35413237'
...