---
res:
  bibo_abstract:
  - The t-haplotype of mice is a classical model for autosomal transmission distortion.
    A largely non-recombining variant of the proximal region of chromosome 17, it
    is transmitted to more than 90% of the progeny of heterozygous males through the
    disabling of sperm carrying a standard chromosome. While extensive genetic and
    functional work has shed light on individual genes involved in drive, much less
    is known about the evolution and function of the rest of its hundreds of genes.
    Here, we characterize the sequence and expression of dozens of t-specific transcripts
    and of their chromosome 17 homologues. Many genes showed reduced expression of
    the t-allele, but an equal number of genes showed increased expression of their
    t-copy, consistent with increased activity or a newly evolved function. Genes
    on the t-haplotype had a significantly higher non-synonymous substitution rate
    than their homologues on the standard chromosome, with several genes harbouring
    dN/dS ratios above 1. Finally, the t-haplotype has acquired at least two genes
    from other chromosomes, which show high and tissue-specific expression. These
    results provide a first overview of the gene content of this selfish element,
    and support a more dynamic evolutionary scenario than expected of a large genomic
    region with almost no recombination.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Réka K
      foaf_name: Kelemen, Réka K
      foaf_surname: Kelemen
      foaf_workInfoHomepage: http://www.librecat.org/personId=48D3F8DE-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8489-9281
  - foaf_Person:
      foaf_givenName: Marwan N
      foaf_name: Elkrewi, Marwan N
      foaf_surname: Elkrewi
      foaf_workInfoHomepage: http://www.librecat.org/personId=0B46FACA-A8E1-11E9-9BD3-79D1E5697425
    orcid: 0000-0002-5328-7231
  - foaf_Person:
      foaf_givenName: Anna K.
      foaf_name: Lindholm, Anna K.
      foaf_surname: Lindholm
  - foaf_Person:
      foaf_givenName: Beatriz
      foaf_name: Vicoso, Beatriz
      foaf_surname: Vicoso
      foaf_workInfoHomepage: http://www.librecat.org/personId=49E1C5C6-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-4579-8306
  bibo_doi: 10.1098/rspb.2021.1985
  bibo_issue: '1968'
  bibo_volume: 289
  dct_date: 2022^xs_gYear
  dct_identifier:
  - UT:000752812800012
  dct_isPartOf:
  - http://id.crossref.org/issn/1471-2954
  dct_language: eng
  dct_publisher: The Royal Society@
  dct_title: Novel patterns of expression and recruitment of new genes on the t-haplotype,
    a mouse selfish chromosome@
  fabio_hasPubmedId: '35135349'
...