---
_id: '10881'
abstract:
- lang: eng
  text: Strigolactones (SLs) are a relatively recent addition to the list of plant
    hormones that control different aspects of plant development. SL signalling is
    perceived by an α/β hydrolase, DWARF 14 (D14). A close homolog of D14, KARRIKIN
    INSENSTIVE2 (KAI2), is involved in perception of an uncharacterized molecule called
    karrikin (KAR). Recent studies in Arabidopsis identified the SUPPRESSOR OF MAX2
    1 (SMAX1) and SMAX1-LIKE 7 (SMXL7) to be potential SCF–MAX2 complex-mediated proteasome
    targets of KAI2 and D14, respectively. Genetic studies on SMXL7 and SMAX1 demonstrated
    distinct developmental roles for each, but very little is known about these repressors
    in terms of their sequence features. In this study, we performed an extensive
    comparative analysis of SMXLs and determined their phylogenetic and evolutionary
    history in the plant lineage. Our results show that SMXL family members can be
    sub-divided into four distinct phylogenetic clades/classes, with an ancient SMAX1.
    Further, we identified the clade-specific motifs that have evolved and that might
    act as determinants of SL-KAR signalling specificity. These specificities resulted
    from functional diversities among the clades. Our results suggest that a gradual
    co-evolution of SMXL members with their upstream receptors D14/KAI2 provided an
    increased specificity to both the SL perception and response in land plants.
acknowledgement: "This project received funding from the European Union’s Horizon
  2020 research and innovation programme under the Marie Skłodowska-Curie Actions
  and it is co-financed by the South Moravian Region under grant agreement No. 665860
  (SS). Access to computing and storage facilities owned by parties and projects contributing
  to the national grid infrastructure, MetaCentrum, provided under the program ‘Projects
  of Large Infrastructure for Research, Development, and Innovations’ (LM2010005)
  was greatly appreciated (RSV). The project was funded by The Ministry of Education,
  Youth and Sports/MES of the Czech Republic under the project CEITEC 2020 (LQ1601)
  (TN, TRM). JF was supported by the European Research Council (project ERC-2011-StG
  20101109-PSDP) and the Czech Science Foundation GAČR (GA13-40637S). We thank Dr
  Kamel Chibani for active discussions on the evolutionary analysis and Nandan Mysore
  Vardarajan for his critical comments on the manuscript. This article reflects\r\nonly
  the authors’ views, and the EU is not responsible for any use that may be made of
  the information it contains. "
article_processing_charge: No
article_type: original
author:
- first_name: Taraka Ramji
  full_name: Moturu, Taraka Ramji
  last_name: Moturu
- first_name: Sravankumar
  full_name: Thula, Sravankumar
  last_name: Thula
- first_name: Ravi Kumar
  full_name: Singh, Ravi Kumar
  last_name: Singh
- first_name: Tomasz
  full_name: Nodzyński, Tomasz
  last_name: Nodzyński
- first_name: Radka Svobodová
  full_name: Vařeková, Radka Svobodová
  last_name: Vařeková
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Sibu
  full_name: Simon, Sibu
  last_name: Simon
citation:
  ama: Moturu TR, Thula S, Singh RK, et al. Molecular evolution and diversification
    of the SMXL gene family. <i>Journal of Experimental Botany</i>. 2018;69(9):2367-2378.
    doi:<a href="https://doi.org/10.1093/jxb/ery097">10.1093/jxb/ery097</a>
  apa: Moturu, T. R., Thula, S., Singh, R. K., Nodzyński, T., Vařeková, R. S., Friml,
    J., &#38; Simon, S. (2018). Molecular evolution and diversification of the SMXL
    gene family. <i>Journal of Experimental Botany</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/jxb/ery097">https://doi.org/10.1093/jxb/ery097</a>
  chicago: Moturu, Taraka Ramji, Sravankumar Thula, Ravi Kumar Singh, Tomasz Nodzyński,
    Radka Svobodová Vařeková, Jiří Friml, and Sibu Simon. “Molecular Evolution and
    Diversification of the SMXL Gene Family.” <i>Journal of Experimental Botany</i>.
    Oxford University Press, 2018. <a href="https://doi.org/10.1093/jxb/ery097">https://doi.org/10.1093/jxb/ery097</a>.
  ieee: T. R. Moturu <i>et al.</i>, “Molecular evolution and diversification of the
    SMXL gene family,” <i>Journal of Experimental Botany</i>, vol. 69, no. 9. Oxford
    University Press, pp. 2367–2378, 2018.
  ista: Moturu TR, Thula S, Singh RK, Nodzyński T, Vařeková RS, Friml J, Simon S.
    2018. Molecular evolution and diversification of the SMXL gene family. Journal
    of Experimental Botany. 69(9), 2367–2378.
  mla: Moturu, Taraka Ramji, et al. “Molecular Evolution and Diversification of the
    SMXL Gene Family.” <i>Journal of Experimental Botany</i>, vol. 69, no. 9, Oxford
    University Press, 2018, pp. 2367–78, doi:<a href="https://doi.org/10.1093/jxb/ery097">10.1093/jxb/ery097</a>.
  short: T.R. Moturu, S. Thula, R.K. Singh, T. Nodzyński, R.S. Vařeková, J. Friml,
    S. Simon, Journal of Experimental Botany 69 (2018) 2367–2378.
date_created: 2022-03-18T12:43:22Z
date_published: 2018-04-13T00:00:00Z
date_updated: 2025-04-15T07:48:01Z
day: '13'
department:
- _id: JiFr
doi: 10.1093/jxb/ery097
ec_funded: 1
external_id:
  isi:
  - '000430727000016'
  pmid:
  - '29538714'
fulldoi: https://doi.org/10.1093/jxb/ery097
intvolume: '        69'
isi: 1
issue: '9'
keyword:
- Plant Science
- Physiology
language:
- iso: eng
month: '04'
oa_version: None
page: 2367-2378
pmid: 1
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: Journal of Experimental Botany
publication_identifier:
  eissn:
  - 1460-2431
  issn:
  - 0022-0957
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular evolution and diversification of the SMXL gene family
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 69
year: '2018'
...