{"article_number":"1964","volume":8,"external_id":{"isi":["000417241200004"]},"abstract":[{"text":"In the early visual system, cells of the same type perform the same computation in different places of the visual field. How these cells code together a complex visual scene is unclear. A common assumption is that cells of a single-type extract a single-stimulus feature to form a feature map, but this has rarely been observed directly. Using large-scale recordings in the rat retina, we show that a homogeneous population of fast OFF ganglion cells simultaneously encodes two radically different features of a visual scene. Cells close to a moving object code quasilinearly for its position, while distant cells remain largely invariant to the object's position and, instead, respond nonlinearly to changes in the object's speed. We develop a quantitative model that accounts for this effect and identify a disinhibitory circuit that mediates it. Ganglion cells of a single type thus do not code for one, but two features simultaneously. This richer, flexible neural map might also be present in other sensory systems.","lang":"eng"}],"_id":"1104","type":"journal_article","date_published":"2017-12-06T00:00:00Z","language":[{"iso":"eng"}],"has_accepted_license":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication_identifier":{"issn":["20411723"]},"scopus_import":"1","publication_status":"published","year":"2017","status":"public","date_created":"2018-12-11T11:50:10Z","file_date_updated":"2018-12-12T10:16:06Z","license":"https://creativecommons.org/licenses/by/4.0/","ddc":["571"],"oa":1,"quality_controlled":"1","oa_version":"Published Version","intvolume":"         8","author":[{"full_name":"Deny, Stephane","first_name":"Stephane","last_name":"Deny"},{"full_name":"Ferrari, Ulisse","first_name":"Ulisse","last_name":"Ferrari"},{"last_name":"Mace","first_name":"Emilie","full_name":"Mace, Emilie"},{"first_name":"Pierre","last_name":"Yger","full_name":"Yger, Pierre"},{"first_name":"Romain","last_name":"Caplette","full_name":"Caplette, Romain"},{"full_name":"Picaud, Serge","last_name":"Picaud","first_name":"Serge"},{"full_name":"Tkacik, Gasper","id":"3D494DCA-F248-11E8-B48F-1D18A9856A87","first_name":"Gasper","last_name":"Tkacik","orcid":"0000-0002-6699-1455"},{"first_name":"Olivier","last_name":"Marre","full_name":"Marre, Olivier"}],"publist_id":"6266","isi":1,"publisher":"Nature Publishing Group","publication":"Nature Communications","doi":"10.1038/s41467-017-02159-y","issue":"1","department":[{"_id":"GaTk"}],"day":"06","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"file":[{"relation":"main_file","file_name":"IST-2018-921-v1+1_s41467-017-02159-y.pdf","access_level":"open_access","creator":"system","file_id":"5191","file_size":2872887,"date_updated":"2018-12-12T10:16:06Z","content_type":"application/pdf","date_created":"2018-12-12T10:16:06Z"}],"month":"12","pubrep_id":"921","date_updated":"2023-09-20T11:41:19Z","project":[{"_id":"25CD3DD2-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","grant_number":"604102","name":"Localization of ion channels and receptors by two and three-dimensional immunoelectron microscopic approaches"},{"name":"Sensitivity to higher-order statistics in natural scenes","grant_number":"P 25651-N26","call_identifier":"FWF","_id":"254D1A94-B435-11E9-9278-68D0E5697425"}],"ec_funded":1,"citation":{"ieee":"S. Deny <i>et al.</i>, “Multiplexed computations in retinal ganglion cells of a single type,” <i>Nature Communications</i>, vol. 8, no. 1. Nature Publishing Group, 2017.","ama":"Deny S, Ferrari U, Mace E, et al. Multiplexed computations in retinal ganglion cells of a single type. <i>Nature Communications</i>. 2017;8(1). doi:<a href=\"https://doi.org/10.1038/s41467-017-02159-y\">10.1038/s41467-017-02159-y</a>","short":"S. Deny, U. Ferrari, E. Mace, P. Yger, R. Caplette, S. Picaud, G. Tkačik, O. Marre, Nature Communications 8 (2017).","mla":"Deny, Stephane, et al. “Multiplexed Computations in Retinal Ganglion Cells of a Single Type.” <i>Nature Communications</i>, vol. 8, no. 1, 1964, Nature Publishing Group, 2017, doi:<a href=\"https://doi.org/10.1038/s41467-017-02159-y\">10.1038/s41467-017-02159-y</a>.","chicago":"Deny, Stephane, Ulisse Ferrari, Emilie Mace, Pierre Yger, Romain Caplette, Serge Picaud, Gašper Tkačik, and Olivier Marre. “Multiplexed Computations in Retinal Ganglion Cells of a Single Type.” <i>Nature Communications</i>. Nature Publishing Group, 2017. <a href=\"https://doi.org/10.1038/s41467-017-02159-y\">https://doi.org/10.1038/s41467-017-02159-y</a>.","ista":"Deny S, Ferrari U, Mace E, Yger P, Caplette R, Picaud S, Tkačik G, Marre O. 2017. Multiplexed computations in retinal ganglion cells of a single type. Nature Communications. 8(1), 1964.","apa":"Deny, S., Ferrari, U., Mace, E., Yger, P., Caplette, R., Picaud, S., … Marre, O. (2017). Multiplexed computations in retinal ganglion cells of a single type. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41467-017-02159-y\">https://doi.org/10.1038/s41467-017-02159-y</a>"},"title":"Multiplexed computations in retinal ganglion cells of a single type","article_processing_charge":"No"}