---
res:
  bibo_abstract:
  - Nuclear pore complexes (NPCs) are built from ∼30 different proteins called nucleoporins
    or Nups. Previous studies have shown that several Nups exhibit cell-type-specific
    expression and that mutations in NPC components result in tissue-specific diseases.
    Here we show that a specific change in NPC composition is required for both myogenic
    and neuronal differentiation. The transmembrane nucleoporin Nup210 is absent in
    proliferating myoblasts and embryonic stem cells (ESCs) but becomes expressed
    and incorporated into NPCs during cell differentiation. Preventing Nup210 production
    by RNAi blocks myogenesis and the differentiation of ESCs into neuroprogenitors.
    We found that the addition of Nup210 to NPCs does not affect nuclear transport
    but is required for the induction of genes that are essential for cell differentiation.
    Our results identify a single change in NPC composition as an essential step in
    cell differentiation and establish a role for Nup210 in gene expression regulation
    and cell fate determination.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Maximiliano A.
      foaf_name: D'Angelo, Maximiliano A.
      foaf_surname: D'Angelo
  - foaf_Person:
      foaf_givenName: J. Sebastian
      foaf_name: Gomez-Cavazos, J. Sebastian
      foaf_surname: Gomez-Cavazos
  - foaf_Person:
      foaf_givenName: Arianna
      foaf_name: Mei, Arianna
      foaf_surname: Mei
  - foaf_Person:
      foaf_givenName: Daniel H.
      foaf_name: Lackner, Daniel H.
      foaf_surname: Lackner
  - foaf_Person:
      foaf_givenName: Martin W
      foaf_name: HETZER, Martin W
      foaf_surname: HETZER
      foaf_workInfoHomepage: http://www.librecat.org/personId=86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
    orcid: 0000-0002-2111-992X
  bibo_doi: 10.1016/j.devcel.2011.11.021
  bibo_issue: '2'
  bibo_volume: 22
  dct_date: 2012^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1534-5807
  dct_language: eng
  dct_publisher: Elsevier@
  dct_subject:
  - Developmental Biology
  - Cell Biology
  - General Biochemistry
  - Genetics and Molecular Biology
  - Molecular Biology
  dct_title: A change in nuclear pore complex composition regulates cell differentiation@
  fabio_hasPubmedId: '22264802'
...