---
_id: '11103'
abstract:
- lang: eng
  text: Over the last decade, the nuclear envelope (NE) has emerged as a key component
    in the organization and function of the nuclear genome. As many as 100 different
    proteins are thought to specifically localize to this double membrane that separates
    the cytoplasm and the nucleoplasm of eukaryotic cells. Selective portals through
    the NE are formed at sites where the inner and outer nuclear membranes are fused,
    and the coincident assembly of ∼30 proteins into nuclear pore complexes occurs.
    These nuclear pore complexes are essential for the control of nucleocytoplasmic
    exchange. Many of the NE and nuclear pore proteins are thought to play crucial
    roles in gene regulation and thus are increasingly linked to human diseases.
article_processing_charge: No
article_type: review
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Susan R.
  full_name: Wente, Susan R.
  last_name: Wente
citation:
  ama: 'Hetzer M, Wente SR. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. <i>Developmental Cell</i>. 2009;17(5):606-616.
    doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>'
  apa: 'Hetzer, M., &#38; Wente, S. R. (2009). Border control at the nucleus: Biogenesis
    and organization of the nuclear membrane and pore complexes. <i>Developmental
    Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>'
  chicago: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>. Elsevier, 2009. <a href="https://doi.org/10.1016/j.devcel.2009.10.007">https://doi.org/10.1016/j.devcel.2009.10.007</a>.'
  ieee: 'M. Hetzer and S. R. Wente, “Border control at the nucleus: Biogenesis and
    organization of the nuclear membrane and pore complexes,” <i>Developmental Cell</i>,
    vol. 17, no. 5. Elsevier, pp. 606–616, 2009.'
  ista: 'Hetzer M, Wente SR. 2009. Border control at the nucleus: Biogenesis and organization
    of the nuclear membrane and pore complexes. Developmental Cell. 17(5), 606–616.'
  mla: 'Hetzer, Martin, and Susan R. Wente. “Border Control at the Nucleus: Biogenesis
    and Organization of the Nuclear Membrane and Pore Complexes.” <i>Developmental
    Cell</i>, vol. 17, no. 5, Elsevier, 2009, pp. 606–16, doi:<a href="https://doi.org/10.1016/j.devcel.2009.10.007">10.1016/j.devcel.2009.10.007</a>.'
  short: M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
date_created: 2022-04-07T07:53:45Z
date_published: 2009-11-17T00:00:00Z
date_updated: 2024-10-14T11:28:25Z
day: '17'
doi: 10.1016/j.devcel.2009.10.007
extern: '1'
external_id:
  pmid:
  - '19922866'
intvolume: '        17'
issue: '5'
keyword:
- Developmental Biology
- Cell Biology
- General Biochemistry
- Genetics and Molecular Biology
- Molecular Biology
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2009.10.007
month: '11'
oa: 1
oa_version: Published Version
page: 606-616
pmid: 1
publication: Developmental Cell
publication_identifier:
  issn:
  - 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Border control at the nucleus: Biogenesis and organization of the nuclear
  membrane and pore complexes'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2009'
...