{"date_created":"2022-04-07T07:56:04Z","publication":"Nature Cell Biology","article_processing_charge":"No","date_published":"2007-09-09T00:00:00Z","year":"2007","author":[{"last_name":"Anderson","full_name":"Anderson, Daniel J.","first_name":"Daniel J."},{"last_name":"HETZER","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed","full_name":"HETZER, Martin W","orcid":"0000-0002-2111-992X","first_name":"Martin W"}],"language":[{"iso":"eng"}],"user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","page":"1160-1166","publisher":"Springer Nature","scopus_import":"1","publication_status":"published","title":"Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum","month":"09","issue":"10","_id":"11115","publication_identifier":{"issn":["1465-7392"],"eissn":["1476-4679"]},"doi":"10.1038/ncb1636","type":"journal_article","citation":{"mla":"Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by Chromatin-Mediated Reorganization of the Endoplasmic Reticulum.” Nature Cell Biology, vol. 9, no. 10, Springer Nature, 2007, pp. 1160–66, doi:10.1038/ncb1636.","ieee":"D. J. Anderson and M. Hetzer, “Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum,” Nature Cell Biology, vol. 9, no. 10. Springer Nature, pp. 1160–1166, 2007.","chicago":"Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by Chromatin-Mediated Reorganization of the Endoplasmic Reticulum.” Nature Cell Biology. Springer Nature, 2007. https://doi.org/10.1038/ncb1636.","ama":"Anderson DJ, Hetzer M. Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum. Nature Cell Biology. 2007;9(10):1160-1166. doi:10.1038/ncb1636","ista":"Anderson DJ, Hetzer M. 2007. Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum. Nature Cell Biology. 9(10), 1160–1166.","apa":"Anderson, D. J., & Hetzer, M. (2007). Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum. Nature Cell Biology. Springer Nature. https://doi.org/10.1038/ncb1636","short":"D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166."},"keyword":["Cell Biology"],"oa_version":"None","status":"public","abstract":[{"text":"The formation of the nuclear envelope (NE) around chromatin is a major membrane-remodelling event that occurs during cell division of metazoa. It is unclear whether the nuclear membrane reforms by the fusion of NE fragments or if it re-emerges from an intact tubular network of the endoplasmic reticulum (ER). Here, we show that NE formation and expansion requires a tubular ER network and occurs efficiently in the presence of the membrane fusion inhibitor GTPγS. Chromatin recruitment of membranes, which is initiated by tubule-end binding, followed by the formation, expansion and sealing of flat membrane sheets, is mediated by DNA-binding proteins residing in the ER. Thus, chromatin plays an active role in reshaping of the ER during NE formation.","lang":"eng"}],"intvolume":" 9","date_updated":"2022-07-18T08:56:38Z","quality_controlled":"1","day":"09","extern":"1","volume":9,"pmid":1,"external_id":{"pmid":["17828249"]},"article_type":"original"}