---
_id: '11115'
abstract:
- lang: eng
  text: The formation of the nuclear envelope (NE) around chromatin is a major membrane-remodelling
    event that occurs during cell division of metazoa. It is unclear whether the nuclear
    membrane reforms by the fusion of NE fragments or if it re-emerges from an intact
    tubular network of the endoplasmic reticulum (ER). Here, we show that NE formation
    and expansion requires a tubular ER network and occurs efficiently in the presence
    of the membrane fusion inhibitor GTPγS. Chromatin recruitment of membranes, which
    is initiated by tubule-end binding, followed by the formation, expansion and sealing
    of flat membrane sheets, is mediated by DNA-binding proteins residing in the ER.
    Thus, chromatin plays an active role in reshaping of the ER during NE formation.
article_processing_charge: No
article_type: original
author:
- first_name: Daniel J.
  full_name: Anderson, Daniel J.
  last_name: Anderson
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
citation:
  ama: Anderson DJ, Hetzer M. Nuclear envelope formation by chromatin-mediated reorganization
    of the endoplasmic reticulum. <i>Nature Cell Biology</i>. 2007;9(10):1160-1166.
    doi:<a href="https://doi.org/10.1038/ncb1636">10.1038/ncb1636</a>
  apa: Anderson, D. J., &#38; Hetzer, M. (2007). Nuclear envelope formation by chromatin-mediated
    reorganization of the endoplasmic reticulum. <i>Nature Cell Biology</i>. Springer
    Nature. <a href="https://doi.org/10.1038/ncb1636">https://doi.org/10.1038/ncb1636</a>
  chicago: Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by
    Chromatin-Mediated Reorganization of the Endoplasmic Reticulum.” <i>Nature Cell
    Biology</i>. Springer Nature, 2007. <a href="https://doi.org/10.1038/ncb1636">https://doi.org/10.1038/ncb1636</a>.
  ieee: D. J. Anderson and M. Hetzer, “Nuclear envelope formation by chromatin-mediated
    reorganization of the endoplasmic reticulum,” <i>Nature Cell Biology</i>, vol.
    9, no. 10. Springer Nature, pp. 1160–1166, 2007.
  ista: Anderson DJ, Hetzer M. 2007. Nuclear envelope formation by chromatin-mediated
    reorganization of the endoplasmic reticulum. Nature Cell Biology. 9(10), 1160–1166.
  mla: Anderson, Daniel J., and Martin Hetzer. “Nuclear Envelope Formation by Chromatin-Mediated
    Reorganization of the Endoplasmic Reticulum.” <i>Nature Cell Biology</i>, vol.
    9, no. 10, Springer Nature, 2007, pp. 1160–66, doi:<a href="https://doi.org/10.1038/ncb1636">10.1038/ncb1636</a>.
  short: D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166.
date_created: 2022-04-07T07:56:04Z
date_published: 2007-09-09T00:00:00Z
date_updated: 2024-10-14T11:30:08Z
day: '09'
doi: 10.1038/ncb1636
extern: '1'
external_id:
  pmid:
  - '17828249'
intvolume: '         9'
issue: '10'
keyword:
- Cell Biology
language:
- iso: eng
month: '09'
oa_version: None
page: 1160-1166
pmid: 1
publication: Nature Cell Biology
publication_identifier:
  eissn:
  - 1476-4679
  issn:
  - 1465-7392
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic
  reticulum
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2007'
...