---
res:
  bibo_abstract:
  - Nuclear pore complexes (NPCs) are large multiprotein assemblies that allow traffic
    between the cytoplasm and the nucleus. During mitosis in higher eukaryotes, the
    Nuclear Envelope (NE) breaks down and NPCs disassemble. How NPCs reassemble and
    incorporate into the NE upon mitotic exit is poorly understood. We demonstrate
    a function for the conserved Nup107-160 complex in this process. Partial in vivo
    depletion of Nup133 or Nup107 via RNAi in HeLa cells resulted in reduced levels
    of multiple nucleoporins and decreased NPC density in the NE. Immunodepletion
    of the entire Nup107-160 complex from in vitro nuclear assembly reactions produced
    nuclei with a continuous NE but no NPCs. This phenotype was reversible only if
    Nup107-160 complex was readded before closed NE formation. Depletion also prevented
    association of FG-repeat nucleoporins with chromatin. We propose a stepwise model
    in which postmitotic NPC assembly initiates on chromatin via early recruitment
    of the Nup107-160 complex.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Tobias C.
      foaf_name: Walther, Tobias C.
      foaf_surname: Walther
  - foaf_Person:
      foaf_givenName: Annabelle
      foaf_name: Alves, Annabelle
      foaf_surname: Alves
  - foaf_Person:
      foaf_givenName: Helen
      foaf_name: Pickersgill, Helen
      foaf_surname: Pickersgill
  - foaf_Person:
      foaf_givenName: Isabelle
      foaf_name: Loı̈odice, Isabelle
      foaf_surname: Loı̈odice
  - foaf_Person:
      foaf_givenName: Martin W
      foaf_name: HETZER, Martin W
      foaf_surname: HETZER
      foaf_workInfoHomepage: http://www.librecat.org/personId=86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
    orcid: 0000-0002-2111-992X
  - foaf_Person:
      foaf_givenName: Vincent
      foaf_name: Galy, Vincent
      foaf_surname: Galy
  - foaf_Person:
      foaf_givenName: Bastian B.
      foaf_name: Hülsmann, Bastian B.
      foaf_surname: Hülsmann
  - foaf_Person:
      foaf_givenName: Thomas
      foaf_name: Köcher, Thomas
      foaf_surname: Köcher
  - foaf_Person:
      foaf_givenName: Matthias
      foaf_name: Wilm, Matthias
      foaf_surname: Wilm
  - foaf_Person:
      foaf_givenName: Terry
      foaf_name: Allen, Terry
      foaf_surname: Allen
  - foaf_Person:
      foaf_givenName: Iain W.
      foaf_name: Mattaj, Iain W.
      foaf_surname: Mattaj
  - foaf_Person:
      foaf_givenName: Valérie
      foaf_name: Doye, Valérie
      foaf_surname: Doye
  bibo_doi: 10.1016/s0092-8674(03)00235-6
  bibo_issue: '2'
  bibo_volume: 113
  dct_date: 2003^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0092-8674
  dct_language: eng
  dct_publisher: Elsevier@
  dct_subject:
  - General Biochemistry
  - Genetics and Molecular Biology
  dct_title: The conserved Nup107-160 complex is critical for nuclear pore complex
    assembly@
  fabio_hasPubmedId: '12705868'
...
