---
_id: '11123'
abstract:
- lang: eng
  text: The small GTPase Ran is a key regulator of nucleocytoplasmic transport during
    interphase. The asymmetric distribution of the GTP-bound form of Ran across the
    nuclear envelope — that is, large quantities in the nucleus compared with small
    quantities in the cytoplasm — determines the directionality of many nuclear transport
    processes. Recent findings that Ran also functions in spindle formation and nuclear
    envelope assembly during mitosis suggest that Ran has a general role in chromatin-centred
    processes. Ran functions in these events as a signal for chromosome position.
article_processing_charge: No
article_type: original
author:
- first_name: Martin W
  full_name: HETZER, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: HETZER
  orcid: 0000-0002-2111-992X
- first_name: Oliver J.
  full_name: Gruss, Oliver J.
  last_name: Gruss
- first_name: Iain W.
  full_name: Mattaj, Iain W.
  last_name: Mattaj
citation:
  ama: Hetzer M, Gruss OJ, Mattaj IW. The Ran GTPase as a marker of chromosome position
    in spindle formation and nuclear envelope assembly. <i>Nature Cell Biology</i>.
    2002;4(7):E177-E184. doi:<a href="https://doi.org/10.1038/ncb0702-e177">10.1038/ncb0702-e177</a>
  apa: Hetzer, M., Gruss, O. J., &#38; Mattaj, I. W. (2002). The Ran GTPase as a marker
    of chromosome position in spindle formation and nuclear envelope assembly. <i>Nature
    Cell Biology</i>. Springer Nature. <a href="https://doi.org/10.1038/ncb0702-e177">https://doi.org/10.1038/ncb0702-e177</a>
  chicago: Hetzer, Martin, Oliver J. Gruss, and Iain W. Mattaj. “The Ran GTPase as
    a Marker of Chromosome Position in Spindle Formation and Nuclear Envelope Assembly.”
    <i>Nature Cell Biology</i>. Springer Nature, 2002. <a href="https://doi.org/10.1038/ncb0702-e177">https://doi.org/10.1038/ncb0702-e177</a>.
  ieee: M. Hetzer, O. J. Gruss, and I. W. Mattaj, “The Ran GTPase as a marker of chromosome
    position in spindle formation and nuclear envelope assembly,” <i>Nature Cell Biology</i>,
    vol. 4, no. 7. Springer Nature, pp. E177–E184, 2002.
  ista: Hetzer M, Gruss OJ, Mattaj IW. 2002. The Ran GTPase as a marker of chromosome
    position in spindle formation and nuclear envelope assembly. Nature Cell Biology.
    4(7), E177–E184.
  mla: Hetzer, Martin, et al. “The Ran GTPase as a Marker of Chromosome Position in
    Spindle Formation and Nuclear Envelope Assembly.” <i>Nature Cell Biology</i>,
    vol. 4, no. 7, Springer Nature, 2002, pp. E177–84, doi:<a href="https://doi.org/10.1038/ncb0702-e177">10.1038/ncb0702-e177</a>.
  short: M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) E177–E184.
date_created: 2022-04-07T07:57:19Z
date_published: 2002-07-01T00:00:00Z
date_updated: 2022-07-18T08:58:03Z
day: '01'
doi: 10.1038/ncb0702-e177
extern: '1'
external_id:
  pmid:
  - '12105431'
intvolume: '         4'
issue: '7'
keyword:
- Cell Biology
language:
- iso: eng
month: '07'
oa_version: None
page: E177-E184
pmid: 1
publication: Nature Cell Biology
publication_identifier:
  eissn:
  - 1476-4679
  issn:
  - 1465-7392
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Ran GTPase as a marker of chromosome position in spindle formation and
  nuclear envelope assembly
type: journal_article
user_id: 72615eeb-f1f3-11ec-aa25-d4573ddc34fd
volume: 4
year: '2002'
...