{"title":"Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly","date_updated":"2022-07-18T08:58:07Z","month":"11","keyword":["Cell Biology"],"article_processing_charge":"No","scopus_import":"1","date_created":"2022-04-07T07:57:42Z","citation":{"ista":"Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW. 2001. Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nature Cell Biology. 3(12), 1086–1091.","short":"M. Hetzer, H.H. Meyer, T.C. Walther, D. Bilbao-Cortes, G. Warren, I.W. Mattaj, Nature Cell Biology 3 (2001) 1086–1091.","ama":"Hetzer M, Meyer HH, Walther TC, Bilbao-Cortes D, Warren G, Mattaj IW. Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. <i>Nature Cell Biology</i>. 2001;3(12):1086-1091. doi:<a href=\"https://doi.org/10.1038/ncb1201-1086\">10.1038/ncb1201-1086</a>","ieee":"M. Hetzer, H. H. Meyer, T. C. Walther, D. Bilbao-Cortes, G. Warren, and I. W. Mattaj, “Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly,” <i>Nature Cell Biology</i>, vol. 3, no. 12. Springer Nature, pp. 1086–1091, 2001.","mla":"Hetzer, Martin, et al. “Distinct AAA-ATPase P97 Complexes Function in Discrete Steps of Nuclear Assembly.” <i>Nature Cell Biology</i>, vol. 3, no. 12, Springer Nature, 2001, pp. 1086–91, doi:<a href=\"https://doi.org/10.1038/ncb1201-1086\">10.1038/ncb1201-1086</a>.","chicago":"Hetzer, Martin, Hemmo H. Meyer, Tobias C. Walther, Daniel Bilbao-Cortes, Graham Warren, and Iain W. Mattaj. “Distinct AAA-ATPase P97 Complexes Function in Discrete Steps of Nuclear Assembly.” <i>Nature Cell Biology</i>. Springer Nature, 2001. <a href=\"https://doi.org/10.1038/ncb1201-1086\">https://doi.org/10.1038/ncb1201-1086</a>.","apa":"Hetzer, M., Meyer, H. H., Walther, T. C., Bilbao-Cortes, D., Warren, G., &#38; Mattaj, I. W. (2001). Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. <i>Nature Cell Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/ncb1201-1086\">https://doi.org/10.1038/ncb1201-1086</a>"},"type":"journal_article","oa_version":"None","extern":"1","status":"public","article_type":"original","publisher":"Springer Nature","issue":"12","year":"2001","abstract":[{"lang":"eng","text":"Although nuclear envelope (NE) assembly is known to require the GTPase Ran, the membrane fusion machinery involved is uncharacterized. NE assembly involves formation of a reticular network on chromatin, fusion of this network into a closed NE and subsequent expansion. Here we show that p97, an AAA-ATPase previously implicated in fusion of Golgi and transitional endoplasmic reticulum (ER) membranes together with the adaptor p47, has two discrete functions in NE assembly. Formation of a closed NE requires the p97–Ufd1–Npl4 complex, not previously implicated in membrane fusion. Subsequent NE growth involves a p97–p47 complex. This study provides the first insights into the molecular mechanisms and specificity of fusion events involved in NE formation."}],"publication_identifier":{"eissn":["1476-4679"],"issn":["1465-7392"]},"doi":"10.1038/ncb1201-1086","pmid":1,"author":[{"first_name":"Martin W","full_name":"HETZER, Martin W","last_name":"HETZER","orcid":"0000-0002-2111-992X","id":"86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed"},{"full_name":"Meyer, Hemmo H.","last_name":"Meyer","first_name":"Hemmo H."},{"first_name":"Tobias C.","full_name":"Walther, Tobias C.","last_name":"Walther"},{"last_name":"Bilbao-Cortes","full_name":"Bilbao-Cortes, Daniel","first_name":"Daniel"},{"last_name":"Warren","full_name":"Warren, Graham","first_name":"Graham"},{"full_name":"Mattaj, Iain W.","last_name":"Mattaj","first_name":"Iain W."}],"volume":3,"_id":"11125","external_id":{"pmid":["11781570"]},"date_published":"2001-11-02T00:00:00Z","publication":"Nature Cell Biology","publication_status":"published","day":"02","page":"1086-1091","user_id":"72615eeb-f1f3-11ec-aa25-d4573ddc34fd","intvolume":"         3","quality_controlled":"1","language":[{"iso":"eng"}]}