---
res:
  bibo_abstract:
  - When Mendel’s work was rediscovered in 1900, and extended to establish classical
    genetics, it was initially seen in opposition to Darwin’s theory of evolution
    by natural selection on continuous variation, as represented by the biometric
    research program that was the foundation of quantitative genetics. As Fisher,
    Haldane, and Wright established a century ago, Mendelian inheritance is exactly
    what is needed for natural selection to work efficiently. Yet, the synthesis remains
    unfinished. We do not understand why sexual reproduction and a fair meiosis predominate
    in eukaryotes, or how far these are responsible for their diversity and complexity.
    Moreover, although quantitative geneticists have long known that adaptive variation
    is highly polygenic, and that this is essential for efficient selection, this
    is only now becoming appreciated by molecular biologists—and we still do not have
    a good framework for understanding polygenic variation or diffuse function.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Nicholas H
      foaf_name: Barton, Nicholas H
      foaf_surname: Barton
      foaf_workInfoHomepage: http://www.librecat.org/personId=4880FE40-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8548-5240
  bibo_doi: 10.1073/pnas.2122147119
  bibo_issue: '30'
  bibo_volume: 119
  dct_date: 2022^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/0027-8424
  - http://id.crossref.org/issn/1091-6490
  dct_language: eng
  dct_publisher: National Academy of Sciences@
  dct_title: The "New Synthesis"@
  fabio_hasPubmedId: '35858408'
...