article published yes Bartholomäus Pieber author 93e5e5b2-0da6-11ed-8a41-af589a0247260000-0001-8689-388X Sabrina Teixeira Martinez author David Cantillo author C. Oliver Kappe author No catalyst required! A highly efficient, catalyst-free process to generate diimide in situ from hydrazine monohydrate and molecular oxygen for the selective reduction of alkenes has been developed. The use of a gas–liquid segmented flow system allowed safe operating conditions and dramatically enhanced this atom-economical reaction, resulting in short processing times. Wiley2013 eng 1433-7851 1521-377310.1002/anie.201303528 523910241-10244 yes Pieber B, Martinez ST, Cantillo D, Kappe CO. In situ generation of diimide from hydrazine and oxygen: Continuous-flow transfer hydrogenation of olefins. <i>Angewandte Chemie International Edition</i>. 2013;52(39):10241-10244. doi:<a href="https://doi.org/10.1002/anie.201303528">10.1002/anie.201303528</a> B. Pieber, S. T. Martinez, D. Cantillo, and C. O. Kappe, “In situ generation of diimide from hydrazine and oxygen: Continuous-flow transfer hydrogenation of olefins,” <i>Angewandte Chemie International Edition</i>, vol. 52, no. 39. Wiley, pp. 10241–10244, 2013. Pieber, Bartholomäus, Sabrina Teixeira Martinez, David Cantillo, and C. Oliver Kappe. “In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous-Flow Transfer Hydrogenation of Olefins.” <i>Angewandte Chemie International Edition</i>. Wiley, 2013. <a href="https://doi.org/10.1002/anie.201303528">https://doi.org/10.1002/anie.201303528</a>. Pieber, B., Martinez, S. T., Cantillo, D., &#38; Kappe, C. O. (2013). In situ generation of diimide from hydrazine and oxygen: Continuous-flow transfer hydrogenation of olefins. <i>Angewandte Chemie International Edition</i>. Wiley. <a href="https://doi.org/10.1002/anie.201303528">https://doi.org/10.1002/anie.201303528</a> Pieber B, Martinez ST, Cantillo D, Kappe CO. 2013. In situ generation of diimide from hydrazine and oxygen: Continuous-flow transfer hydrogenation of olefins. Angewandte Chemie International Edition. 52(39), 10241–10244. B. Pieber, S.T. Martinez, D. Cantillo, C.O. Kappe, Angewandte Chemie International Edition 52 (2013) 10241–10244. Pieber, Bartholomäus, et al. “In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous-Flow Transfer Hydrogenation of Olefins.” <i>Angewandte Chemie International Edition</i>, vol. 52, no. 39, Wiley, 2013, pp. 10241–44, doi:<a href="https://doi.org/10.1002/anie.201303528">10.1002/anie.201303528</a>. 119592022-08-24T11:01:47Z2023-02-21T10:09:21Z