article published yes Matthew B. Plutschack author Bartholomäus Pieber author 93e5e5b2-0da6-11ed-8a41-af589a0247260000-0001-8689-388X Kerry Gilmore author Peter H. Seeberger author Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous stream rather than in a flask. Flow equipment provides chemists with unique control over reaction parameters enhancing reactivity or in some cases enabling new reactions. This relatively young technology has received a remarkable amount of attention in the past decade with many reports on what can be done in flow. Until recently, however, the question, “Should we do this in flow?” has merely been an afterthought. This review introduces readers to the basic principles and fundamentals of flow chemistry and critically discusses recent flow chemistry accounts. American Chemical Society2017 eng 0009-2665 1520-6890 2857005910.1021/acs.chemrev.7b00183 1171811796-11893 yes Plutschack MB, Pieber B, Gilmore K, Seeberger PH. The Hitchhiker’s Guide to flow chemistry. <i>Chemical Reviews</i>. 2017;117(18):11796-11893. doi:<a href="https://doi.org/10.1021/acs.chemrev.7b00183">10.1021/acs.chemrev.7b00183</a> Plutschack, Matthew B., Bartholomäus Pieber, Kerry Gilmore, and Peter H. Seeberger. “The Hitchhiker’s Guide to Flow Chemistry.” <i>Chemical Reviews</i>. American Chemical Society, 2017. <a href="https://doi.org/10.1021/acs.chemrev.7b00183">https://doi.org/10.1021/acs.chemrev.7b00183</a>. Plutschack MB, Pieber B, Gilmore K, Seeberger PH. 2017. The Hitchhiker’s Guide to flow chemistry. Chemical Reviews. 117(18), 11796–11893. Plutschack, Matthew B., et al. “The Hitchhiker’s Guide to Flow Chemistry.” <i>Chemical Reviews</i>, vol. 117, no. 18, American Chemical Society, 2017, pp. 11796–893, doi:<a href="https://doi.org/10.1021/acs.chemrev.7b00183">10.1021/acs.chemrev.7b00183</a>. Plutschack, M. B., Pieber, B., Gilmore, K., &#38; Seeberger, P. H. (2017). The Hitchhiker’s Guide to flow chemistry. <i>Chemical Reviews</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.chemrev.7b00183">https://doi.org/10.1021/acs.chemrev.7b00183</a> M. B. Plutschack, B. Pieber, K. Gilmore, and P. H. Seeberger, “The Hitchhiker’s Guide to flow chemistry,” <i>Chemical Reviews</i>, vol. 117, no. 18. American Chemical Society, pp. 11796–11893, 2017. M.B. Plutschack, B. Pieber, K. Gilmore, P.H. Seeberger, Chemical Reviews 117 (2017) 11796–11893. 119612022-08-24T11:07:46Z2023-02-21T10:09:28Z