Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow Pieber, Bartholomäus ; https://orcid.org/0000-0001-8689-388X Glasnov, Toma Kappe, C. O. A method for the direct lithiation of terminal alkynes and heterocycles with subsequent carboxylation in a continuous flow format was developed. This method provides carboxylic acids at ambient conditions within less than five seconds with only little excess of the organometallic base and CO2. Royal Society of Chemistry 2014 info:eu-repo/semantics/article doc-type:article text http://purl.org/coar/resource_type/c_6501 https://research-explorer.ista.ac.at/record/11987 Pieber B, Glasnov T, Kappe CO. Flash carboxylation: Fast lithiation–carboxylation sequence at room temperature in continuous flow. <i>RSC Advances</i>. 2014;4(26). doi:<a href="https://doi.org/10.1039/c4ra01442a">10.1039/c4ra01442a</a> eng info:eu-repo/semantics/altIdentifier/doi/10.1039/c4ra01442a info:eu-repo/semantics/altIdentifier/e-issn/2046-2069 info:eu-repo/semantics/closedAccess