---
res:
  bibo_abstract:
  - "The Arabidopsis thaliana endogenous elicitor peptides (AtPeps) are released into
    the apoplast after cellular damage caused by pathogens or wounding to induce innate
    immunity by direct binding to the membrane-localized leucine-rich repeat receptor
    kinases, PEP RECEPTOR1 (PEPR1) and PEPR2. Although the PEPR-mediated signaling
    components and responses have been studied extensively, the contributions of the
    subcellular localization and dynamics of the active PEPRs remain largely unknown.
    We used live-cell imaging of the fluorescently labeled and bioactive pep1 to visualize
    the intracellular behavior of the PEPRs in the Arabidopsis root meristem. We found
    that AtPep1 decorated the plasma membrane (PM) in a receptor-dependent manner
    and cointernalized with PEPRs. Trafficking of the AtPep1-PEPR1 complexes to the
    vacuole required neither the trans-Golgi network/early endosome (TGN/EE)-localized
    vacuolar H+ -ATPase activity nor the function of the brefeldin A-sensitive ADP-ribosylation
    factor-guanine exchange factors (ARF-GEFs). In addition, AtPep1 and different
    TGN/EE markers colocalized only rarely, implying that the intracellular route
    of this receptor-ligand pair is largely independent of the TGN/EE. Inducible overexpression
    of the Arabidopsis clathrin coat disassembly factor, Auxilin2, which inhibits
    clathrin-mediated endocytosis (CME), impaired the AtPep1-PEPR1 internalization
    and compromised AtPep1-mediated responses. Our results show that clathrin function
    at the PM is required to induce plant defense responses, likely through CME of
    cell surface-located signaling components.\r\n@eng"
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Fausto
      foaf_name: Ortiz Morea, Fausto
      foaf_surname: Ortiz Morea
  - foaf_Person:
      foaf_givenName: Daniel
      foaf_name: Savatin, Daniel
      foaf_surname: Savatin
  - foaf_Person:
      foaf_givenName: Wim
      foaf_name: Dejonghe, Wim
      foaf_surname: Dejonghe
  - foaf_Person:
      foaf_givenName: Rahul
      foaf_name: Kumar, Rahul
      foaf_surname: Kumar
  - foaf_Person:
      foaf_givenName: Yu
      foaf_name: Luo, Yu
      foaf_surname: Luo
  - foaf_Person:
      foaf_givenName: Maciek
      foaf_name: Adamowski, Maciek
      foaf_surname: Adamowski
      foaf_workInfoHomepage: http://www.librecat.org/personId=45F536D2-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-6463-5257
  - foaf_Person:
      foaf_givenName: Jos
      foaf_name: Van Begin, Jos
      foaf_surname: Van Begin
  - foaf_Person:
      foaf_givenName: Keini
      foaf_name: Dressano, Keini
      foaf_surname: Dressano
  - foaf_Person:
      foaf_givenName: Guilherme
      foaf_name: De Oliveira, Guilherme
      foaf_surname: De Oliveira
  - foaf_Person:
      foaf_givenName: Xiuyang
      foaf_name: Zhao, Xiuyang
      foaf_surname: Zhao
  - foaf_Person:
      foaf_givenName: Qing
      foaf_name: Lu, Qing
      foaf_surname: Lu
  - foaf_Person:
      foaf_givenName: Annemieke
      foaf_name: Madder, Annemieke
      foaf_surname: Madder
  - foaf_Person:
      foaf_givenName: Jirí
      foaf_name: Friml, Jirí
      foaf_surname: Friml
      foaf_workInfoHomepage: http://www.librecat.org/personId=4159519E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8302-7596
  - foaf_Person:
      foaf_givenName: Daniel
      foaf_name: De Moura, Daniel
      foaf_surname: De Moura
  - foaf_Person:
      foaf_givenName: Eugenia
      foaf_name: Russinova, Eugenia
      foaf_surname: Russinova
  bibo_doi: 10.1073/pnas.1605588113
  bibo_issue: '39'
  bibo_volume: 113
  dct_date: 2016^xs_gYear
  dct_identifier:
  - UT:000383954700066
  dct_language: eng
  dct_publisher: National Academy of Sciences@
  dct_title: Danger-associated peptide signaling in Arabidopsis requires clathrin@
...