---
res:
  bibo_abstract:
  - 'Linear tetrapyrroles, called phyllobilins, are obtained as major catabolites
    upon chlorophyll degradation. Primarily, colorless phylloleucobilins featuring
    four deconjugated pyrrole units were identified. Their yellow counterparts, phylloxanthobilins,
    were discovered more recently. Although the two catabolites differ only by one
    double bond, physicochemical properties are very distinct. Moreover, the presence
    of the double bond seems to enhance physiologically relevant bioactivities: in
    contrast to phylloleucobilin, we identified a potent anti-proliferative activity
    for a phylloxanthobilin, and show that this natural product induces apoptotic
    cell death and a cell cycle arrest in cancer cells. Interestingly, upon modifying
    inactive phylloleucobilin by esterification, an anti-proliferative activity can
    be observed that increases with the chain lengths of the alkyl esters. We provide
    first evidence for anti-cancer activity of phyllobilins, report a novel plant
    source for a phylloxanthobilin, and by using paper spray MS, show that these bioactive
    yellow chlorophyll catabolites are more prevalent in Nature than previously assumed.@eng'
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Cornelia A.
      foaf_name: Karg, Cornelia A.
      foaf_surname: Karg
  - foaf_Person:
      foaf_givenName: Pengyu
      foaf_name: Wang, Pengyu
      foaf_surname: Wang
  - foaf_Person:
      foaf_givenName: Florian
      foaf_name: Kluibenschedl, Florian
      foaf_surname: Kluibenschedl
      foaf_workInfoHomepage: http://www.librecat.org/personId=7499e70e-eb2c-11ec-b98b-f925648bc9d9
  - foaf_Person:
      foaf_givenName: Thomas
      foaf_name: Müller, Thomas
      foaf_surname: Müller
  - foaf_Person:
      foaf_givenName: Lars
      foaf_name: Allmendinger, Lars
      foaf_surname: Allmendinger
  - foaf_Person:
      foaf_givenName: Angelika M.
      foaf_name: Vollmar, Angelika M.
      foaf_surname: Vollmar
  - foaf_Person:
      foaf_givenName: Simone
      foaf_name: Moser, Simone
      foaf_surname: Moser
  bibo_doi: 10.1002/ejoc.202000692
  bibo_issue: '29'
  bibo_volume: 2020
  dct_date: 2020^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1434-193X
  - http://id.crossref.org/issn/1099-0690
  dct_language: eng
  dct_publisher: Wiley@
  dct_subject:
  - Organic Chemistry
  - Physical and Theoretical Chemistry
  dct_title: Phylloxanthobilins are abundant linear tetrapyrroles from chlorophyll
    breakdown with activities against cancer cells@
...