---
_id: '13066'
abstract:
- lang: eng
  text: Chromosomal inversions have been shown to play a major role in local adaptation
    by suppressing recombination between alternative arrangements and maintaining
    beneficial allele combinations. However, so far, their importance relative to
    the remaining genome remains largely unknown. Understanding the genetic architecture
    of adaptation requires better estimates of how loci of different effect sizes
    contribute to phenotypic variation. Here, we used three Swedish islands where
    the marine snail Littorina saxatilis has repeatedly evolved into two distinct
    ecotypes along a habitat transition. We estimated the contribution of inversion
    polymorphisms to phenotypic divergence while controlling for polygenic effects
    in the remaining genome using a quantitative genetics framework. We confirmed
    the importance of inversions but showed that contributions of loci outside inversions
    are of similar magnitude, with variable proportions dependent on the trait and
    the population. Some inversions showed consistent effects across all sites, whereas
    others exhibited site-specific effects, indicating that the genomic basis for
    replicated phenotypic divergence is only partly shared. The contributions of sexual
    dimorphism as well as environmental factors to phenotypic variation were significant
    but minor compared to inversions and polygenic background. Overall, this integrated
    approach provides insight into the multiple mechanisms contributing to parallel
    phenotypic divergence.
article_processing_charge: No
author:
- first_name: Eva
  full_name: Koch, Eva
  last_name: Koch
- first_name: Mark
  full_name: Ravinet, Mark
  last_name: Ravinet
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Kerstin
  full_name: Jonannesson, Kerstin
  last_name: Jonannesson
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Koch E, Ravinet M, Westram AM, Jonannesson K, Butlin R. Data from: Genetic
    architecture of repeated phenotypic divergence in Littorina saxatilis ecotype
    evolution. 2022. doi:<a href="https://doi.org/10.5061/DRYAD.M905QFV4B">10.5061/DRYAD.M905QFV4B</a>'
  apa: 'Koch, E., Ravinet, M., Westram, A. M., Jonannesson, K., &#38; Butlin, R. (2022).
    Data from: Genetic architecture of repeated phenotypic divergence in Littorina
    saxatilis ecotype evolution. Dryad. <a href="https://doi.org/10.5061/DRYAD.M905QFV4B">https://doi.org/10.5061/DRYAD.M905QFV4B</a>'
  chicago: 'Koch, Eva, Mark Ravinet, Anja M Westram, Kerstin Jonannesson, and Roger
    Butlin. “Data from: Genetic Architecture of Repeated Phenotypic Divergence in
    Littorina Saxatilis Ecotype Evolution.” Dryad, 2022. <a href="https://doi.org/10.5061/DRYAD.M905QFV4B">https://doi.org/10.5061/DRYAD.M905QFV4B</a>.'
  ieee: 'E. Koch, M. Ravinet, A. M. Westram, K. Jonannesson, and R. Butlin, “Data
    from: Genetic architecture of repeated phenotypic divergence in Littorina saxatilis
    ecotype evolution.” Dryad, 2022.'
  ista: 'Koch E, Ravinet M, Westram AM, Jonannesson K, Butlin R. 2022. Data from:
    Genetic architecture of repeated phenotypic divergence in Littorina saxatilis
    ecotype evolution, Dryad, <a href="https://doi.org/10.5061/DRYAD.M905QFV4B">10.5061/DRYAD.M905QFV4B</a>.'
  mla: 'Koch, Eva, et al. <i>Data from: Genetic Architecture of Repeated Phenotypic
    Divergence in Littorina Saxatilis Ecotype Evolution</i>. Dryad, 2022, doi:<a href="https://doi.org/10.5061/DRYAD.M905QFV4B">10.5061/DRYAD.M905QFV4B</a>.'
  short: E. Koch, M. Ravinet, A.M. Westram, K. Jonannesson, R. Butlin, (2022).
date_created: 2023-05-23T16:33:12Z
date_published: 2022-07-28T00:00:00Z
date_updated: 2023-08-04T09:42:10Z
day: '28'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.M905QFV4B
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.m905qfv4b
month: '07'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '12247'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Genetic architecture of repeated phenotypic divergence in Littorina
  saxatilis ecotype evolution'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...