---
res:
  bibo_abstract:
  - XY systems usually show chromosome-wide compensation of X-linked genes, while
    in many ZW systems, compensation is restricted to a minority of dosage-sensitive
    genes. Why such differences arose is still unclear. Here, we combine comparative
    genomics, transcriptomics and proteomics to obtain a complete overview of the
    evolution of gene dosage on the Z-chromosome of Schistosoma parasites. We compare
    the Z-chromosome gene content of African (Schistosoma mansoni and S. haematobium)
    and Asian (S. japonicum) schistosomes and describe lineage-specific evolutionary
    strata. We use these to assess gene expression evolution following sex-linkage.
    The resulting patterns suggest a reduction in expression of Z-linked genes in
    females, combined with upregulation of the Z in both sexes, in line with the first
    step of Ohno’s classic model of dosage compensation evolution. Quantitative proteomics
    suggest that post-transcriptional mechanisms do not play a major role in balancing
    the expression of Z-linked genes. @eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Marion A
      foaf_name: Picard, Marion A
      foaf_surname: Picard
      foaf_workInfoHomepage: http://www.librecat.org/personId=2C921A7A-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-8101-2518
  - foaf_Person:
      foaf_givenName: Celine
      foaf_name: Cosseau, Celine
      foaf_surname: Cosseau
  - foaf_Person:
      foaf_givenName: Sabrina
      foaf_name: Ferré, Sabrina
      foaf_surname: Ferré
  - foaf_Person:
      foaf_givenName: Thomas
      foaf_name: Quack, Thomas
      foaf_surname: Quack
  - foaf_Person:
      foaf_givenName: Christoph
      foaf_name: Grevelding, Christoph
      foaf_surname: Grevelding
  - foaf_Person:
      foaf_givenName: Yohann
      foaf_name: Couté, Yohann
      foaf_surname: Couté
  - foaf_Person:
      foaf_givenName: Beatriz
      foaf_name: Vicoso, Beatriz
      foaf_surname: Vicoso
      foaf_workInfoHomepage: http://www.librecat.org/personId=49E1C5C6-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-4579-8306
  bibo_doi: 10.7554/eLife.35684
  bibo_volume: 7
  dct_date: 2018^xs_gYear
  dct_identifier:
  - UT:000441388200001
  dct_language: eng
  dct_publisher: eLife Sciences Publications@
  dct_title: Evolution of gene dosage on the Z-chromosome of schistosome parasites@
...