{"scopus_import":"1","pmid":1,"quality_controlled":"1","date_published":"2019-11-13T00:00:00Z","volume":116,"publication_identifier":{"issn":["0027-8424"],"eissn":["1091-6490"]},"article_processing_charge":"No","title":"Real-time probing of chirality during a chemical reaction","citation":{"short":"D.R. Baykusheva, D. Zindel, V. Svoboda, E. Bommeli, M. Ochsner, A. Tehlar, H.J. Wörner, Proceedings of the National Academy of Sciences 116 (2019) 23923–23929.","ama":"Baykusheva DR, Zindel D, Svoboda V, et al. Real-time probing of chirality during a chemical reaction. <i>Proceedings of the National Academy of Sciences</i>. 2019;116(48):23923-23929. doi:<a href=\"https://doi.org/10.1073/pnas.1907189116\">10.1073/pnas.1907189116</a>","chicago":"Baykusheva, Denitsa Rangelova, Daniel Zindel, Vít Svoboda, Elias Bommeli, Manuel Ochsner, Andres Tehlar, and Hans Jakob Wörner. “Real-Time Probing of Chirality during a Chemical Reaction.” <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences, 2019. <a href=\"https://doi.org/10.1073/pnas.1907189116\">https://doi.org/10.1073/pnas.1907189116</a>.","apa":"Baykusheva, D. R., Zindel, D., Svoboda, V., Bommeli, E., Ochsner, M., Tehlar, A., &#38; Wörner, H. J. (2019). Real-time probing of chirality during a chemical reaction. <i>Proceedings of the National Academy of Sciences</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1907189116\">https://doi.org/10.1073/pnas.1907189116</a>","ieee":"D. R. Baykusheva <i>et al.</i>, “Real-time probing of chirality during a chemical reaction,” <i>Proceedings of the National Academy of Sciences</i>, vol. 116, no. 48. Proceedings of the National Academy of Sciences, pp. 23923–23929, 2019.","ista":"Baykusheva DR, Zindel D, Svoboda V, Bommeli E, Ochsner M, Tehlar A, Wörner HJ. 2019. Real-time probing of chirality during a chemical reaction. Proceedings of the National Academy of Sciences. 116(48), 23923–23929.","mla":"Baykusheva, Denitsa Rangelova, et al. “Real-Time Probing of Chirality during a Chemical Reaction.” <i>Proceedings of the National Academy of Sciences</i>, vol. 116, no. 48, Proceedings of the National Academy of Sciences, 2019, pp. 23923–29, doi:<a href=\"https://doi.org/10.1073/pnas.1907189116\">10.1073/pnas.1907189116</a>."},"intvolume":"       116","page":"23923-23929","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1073/pnas.1907189116"}],"day":"13","language":[{"iso":"eng"}],"author":[{"id":"71b4d059-2a03-11ee-914d-dfa3beed6530","full_name":"Baykusheva, Denitsa Rangelova","last_name":"Baykusheva","first_name":"Denitsa Rangelova"},{"last_name":"Zindel","first_name":"Daniel","full_name":"Zindel, Daniel"},{"full_name":"Svoboda, Vít","first_name":"Vít","last_name":"Svoboda"},{"first_name":"Elias","last_name":"Bommeli","full_name":"Bommeli, Elias"},{"full_name":"Ochsner, Manuel","first_name":"Manuel","last_name":"Ochsner"},{"full_name":"Tehlar, Andres","last_name":"Tehlar","first_name":"Andres"},{"full_name":"Wörner, Hans Jakob","last_name":"Wörner","first_name":"Hans Jakob"}],"year":"2019","oa":1,"abstract":[{"lang":"eng","text":"Chiral molecules interact and react differently with other chiral objects, depending on their handedness. Therefore, it is essential to understand and ultimately control the evolution of molecular chirality during chemical reactions. Although highly sophisticated techniques for the controlled synthesis of chiral molecules have been developed, the observation of chirality on the natural femtosecond time scale of a chemical reaction has so far remained out of reach in the gas phase. Here, we demonstrate a general experimental technique, based on high-harmonic generation in tailored laser fields, and apply it to probe the time evolution of molecular chirality during the photodissociation of 2-iodobutane. These measurements show a change in sign and a pronounced increase in the magnitude of the chiral response over the first 100 fs, followed by its decay within less than 500 fs, revealing the photodissociation to achiral products. The observed time evolution is explained in terms of the variation of the electric and magnetic transition-dipole moments between the lowest electronic states of the cation as a function of the reaction coordinate. These results open the path to investigations of the chirality of molecular-reaction pathways, light-induced chirality in chemical processes, and the control of molecular chirality through tailored laser pulses."}],"_id":"14001","extern":"1","article_type":"original","keyword":["Multidisciplinary"],"status":"public","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2023-08-22T07:40:05Z","type":"journal_article","oa_version":"Published Version","doi":"10.1073/pnas.1907189116","issue":"48","publication":"Proceedings of the National Academy of Sciences","external_id":{"arxiv":["1906.10818"],"pmid":["31723044"]},"publisher":"Proceedings of the National Academy of Sciences","publication_status":"published","month":"11","date_created":"2023-08-09T13:10:36Z"}