---
res:
  bibo_abstract:
  - Mapping the complex and dense arrangement of cells and their connectivity in brain
    tissue demands nanoscale spatial resolution imaging. Super-resolution optical
    microscopy excels at visualizing specific molecules and individual cells but fails
    to provide tissue context. Here we developed Comprehensive Analysis of Tissues
    across Scales (CATS), a technology to densely map brain tissue architecture from
    millimeter regional to nanometer synaptic scales in diverse chemically fixed brain
    preparations, including rodent and human. CATS uses fixation-compatible extracellular
    labeling and optical imaging, including stimulated emission depletion or expansion
    microscopy, to comprehensively delineate cellular structures. It enables three-dimensional
    reconstruction of single synapses and mapping of synaptic connectivity by identification
    and analysis of putative synaptic cleft regions. Applying CATS to the mouse hippocampal
    mossy fiber circuitry, we reconstructed and quantified the synaptic input and
    output structure of identified neurons. We furthermore demonstrate applicability
    to clinically derived human tissue samples, including formalin-fixed paraffin-embedded
    routine diagnostic specimens, for visualizing the cellular architecture of brain
    tissue in health and disease.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Julia M
      foaf_name: Michalska, Julia M
      foaf_surname: Michalska
      foaf_workInfoHomepage: http://www.librecat.org/personId=443DB6DE-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-3862-1235
  - foaf_Person:
      foaf_givenName: Julia
      foaf_name: Lyudchik, Julia
      foaf_surname: Lyudchik
      foaf_workInfoHomepage: http://www.librecat.org/personId=46E28B80-F248-11E8-B48F-1D18A9856A87
  - foaf_Person:
      foaf_givenName: Philipp
      foaf_name: Velicky, Philipp
      foaf_surname: Velicky
      foaf_workInfoHomepage: http://www.librecat.org/personId=39BDC62C-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-2340-7431
  - foaf_Person:
      foaf_givenName: Hana
      foaf_name: Korinkova, Hana
      foaf_surname: Korinkova
      foaf_workInfoHomepage: http://www.librecat.org/personId=ee3cb6ca-ec98-11ea-ae11-ff703e2254ed
  - foaf_Person:
      foaf_givenName: Jake
      foaf_name: Watson, Jake
      foaf_surname: Watson
      foaf_workInfoHomepage: http://www.librecat.org/personId=63836096-4690-11EA-BD4E-32803DDC885E
    orcid: 0000-0002-8698-3823
  - foaf_Person:
      foaf_givenName: Alban
      foaf_name: Cenameri, Alban
      foaf_surname: Cenameri
      foaf_workInfoHomepage: http://www.librecat.org/personId=9ac8f577-2357-11eb-997a-e566c5550886
  - foaf_Person:
      foaf_givenName: Christoph M
      foaf_name: Sommer, Christoph M
      foaf_surname: Sommer
      foaf_workInfoHomepage: http://www.librecat.org/personId=4DF26D8C-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-1216-9105
  - foaf_Person:
      foaf_givenName: Nicole
      foaf_name: Amberg, Nicole
      foaf_surname: Amberg
      foaf_workInfoHomepage: http://www.librecat.org/personId=4CD6AAC6-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-3183-8207
  - foaf_Person:
      foaf_givenName: Alessandro
      foaf_name: Venturino, Alessandro
      foaf_surname: Venturino
      foaf_workInfoHomepage: http://www.librecat.org/personId=41CB84B2-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0003-2356-9403
  - foaf_Person:
      foaf_givenName: Karl
      foaf_name: Roessler, Karl
      foaf_surname: Roessler
  - foaf_Person:
      foaf_givenName: Thomas
      foaf_name: Czech, Thomas
      foaf_surname: Czech
  - foaf_Person:
      foaf_givenName: Romana
      foaf_name: Höftberger, Romana
      foaf_surname: Höftberger
  - foaf_Person:
      foaf_givenName: Sandra
      foaf_name: Siegert, Sandra
      foaf_surname: Siegert
      foaf_workInfoHomepage: http://www.librecat.org/personId=36ACD32E-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8635-0877
  - foaf_Person:
      foaf_givenName: Gaia
      foaf_name: Novarino, Gaia
      foaf_surname: Novarino
      foaf_workInfoHomepage: http://www.librecat.org/personId=3E57A680-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0002-7673-7178
  - foaf_Person:
      foaf_givenName: Peter M
      foaf_name: Jonas, Peter M
      foaf_surname: Jonas
      foaf_workInfoHomepage: http://www.librecat.org/personId=353C1B58-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-5001-4804
  - foaf_Person:
      foaf_givenName: Johann G
      foaf_name: Danzl, Johann G
      foaf_surname: Danzl
      foaf_workInfoHomepage: http://www.librecat.org/personId=42EFD3B6-F248-11E8-B48F-1D18A9856A87
    orcid: 0000-0001-8559-3973
  bibo_doi: 10.1038/s41587-023-01911-8
  bibo_volume: 42
  dct_date: 2024^xs_gYear
  dct_identifier:
  - UT:001065254200001
  dct_isPartOf:
  - http://id.crossref.org/issn/1087-0156
  - http://id.crossref.org/issn/1546-1696
  dct_language: eng
  dct_publisher: Springer Nature@
  dct_title: Imaging brain tissue architecture across millimeter to nanometer scales@
  fabio_hasPubmedId: '37653226'
...