---
res:
  bibo_abstract:
  - One key goal of DNA nanotechnology is the bottom-up construction of macroscopic
    crystalline materials. Beyond applications in fields such as photonics or plasmonics,
    DNA-based crystal matrices could possibly facilitate the diffraction-based structural
    analysis of guest molecules. Seeman and co-workers reported in 2009 the first
    designed crystal matrices based on a 38 kDa DNA triangle that was composed of
    seven chains. The crystal lattice was stabilized, unprecedentedly, by Watson–Crick
    base pairing. However, 3D crystallization of larger designed DNA objects that
    include more chains such as DNA origami remains an unsolved problem. Larger objects
    would offer more degrees of freedom and design options with respect to tailoring
    lattice geometry and for positioning other objects within a crystal lattice. The
    greater rigidity of multilayer DNA origami could also positively influence the
    diffractive properties of crystals composed of such particles. Here, we rationally
    explore the role of heterogeneity and Watson–Crick interaction strengths in crystal
    growth using 40 variants of the original DNA triangle as model multichain objects.
    Crystal growth of the triangle was remarkably robust despite massive chemical,
    geometrical, and thermodynamical sample heterogeneity that we introduced, but
    the crystal growth sensitively depended on the sequences of base pairs next to
    the Watson–Crick sticky ends of the triangle. Our results point to weak lattice
    interactions and high concentrations as decisive factors for achieving productive
    crystallization, while sample heterogeneity and impurities played a minor role.@eng
  bibo_authorlist:
  - foaf_Person:
      foaf_givenName: Evi
      foaf_name: Stahl, Evi
      foaf_surname: Stahl
  - foaf_Person:
      foaf_givenName: Florian M
      foaf_name: Praetorius, Florian M
      foaf_surname: Praetorius
      foaf_workInfoHomepage: http://www.librecat.org/personId=dfec9381-4341-11ee-8fd8-faa02bba7d62
  - foaf_Person:
      foaf_givenName: Carina C.
      foaf_name: de Oliveira Mann, Carina C.
      foaf_surname: de Oliveira Mann
  - foaf_Person:
      foaf_givenName: Karl-Peter
      foaf_name: Hopfner, Karl-Peter
      foaf_surname: Hopfner
  - foaf_Person:
      foaf_givenName: Hendrik
      foaf_name: Dietz, Hendrik
      foaf_surname: Dietz
  bibo_doi: 10.1021/acsnano.6b04787
  bibo_issue: '10'
  bibo_volume: 10
  dct_date: 2016^xs_gYear
  dct_isPartOf:
  - http://id.crossref.org/issn/1936-0851
  - http://id.crossref.org/issn/1936-086X
  dct_language: eng
  dct_publisher: American Chemical Society@
  dct_title: Impact of heterogeneity and lattice bond strength on DNA triangle crystal
    growth@
  fabio_hasPubmedId: '27583560'
...