---
_id: '14341'
abstract:
- lang: eng
  text: Flows through pipes and channels are, in practice, almost always turbulent,
    and the multiscale eddying motion is responsible for a major part of the encountered
    friction losses and pumping costs1. Conversely, for pulsatile flows, in particular
    for aortic blood flow, turbulence levels remain low despite relatively large peak
    velocities. For aortic blood flow, high turbulence levels are intolerable as they
    would damage the shear-sensitive endothelial cell layer2,3,4,5. Here we show that
    turbulence in ordinary pipe flow is diminished if the flow is driven in a pulsatile
    mode that incorporates all the key features of the cardiac waveform. At Reynolds
    numbers comparable to those of aortic blood flow, turbulence is largely inhibited,
    whereas at much higher speeds, the turbulent drag is reduced by more than 25%.
    This specific operation mode is more efficient when compared with steady driving,
    which is the present situation for virtually all fluid transport processes ranging
    from heating circuits to water, gas and oil pipelines.
acknowledged_ssus:
- _id: M-Shop
- _id: ScienComp
acknowledgement: We acknowledge the assistance of the Miba machine shop and the team
  of the ISTA-HPC cluster. We thank M. Quadrio for the discussions. The work was supported
  by the Simons Foundation (grant no. 662960) and by the Austrian Science Fund (grant
  no. I4188-N30), within Deutsche Forschungsgemeinschaft research unit FOR 2688.
article_processing_charge: No
article_type: original
author:
- first_name: Davide
  full_name: Scarselli, Davide
  id: 40315C30-F248-11E8-B48F-1D18A9856A87
  last_name: Scarselli
  orcid: 0000-0001-5227-4271
- first_name: Jose M
  full_name: Lopez Alonso, Jose M
  id: 40770848-F248-11E8-B48F-1D18A9856A87
  last_name: Lopez Alonso
  orcid: 0000-0002-0384-2022
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. Turbulence suppression by
    cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. 2023;621(7977):71-74.
    doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>
  apa: Scarselli, D., Lopez Alonso, J. M., Varshney, A., &#38; Hof, B. (2023). Turbulence
    suppression by cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>
  chicago: Scarselli, Davide, Jose M Lopez Alonso, Atul Varshney, and Björn Hof. “Turbulence
    Suppression by Cardiac-Cycle-Inspired Driving of Pipe Flow.” <i>Nature</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>.
  ieee: D. Scarselli, J. M. Lopez Alonso, A. Varshney, and B. Hof, “Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow,” <i>Nature</i>, vol. 621, no.
    7977. Springer Nature, pp. 71–74, 2023.
  ista: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. 2023. Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow. Nature. 621(7977), 71–74.
  mla: Scarselli, Davide, et al. “Turbulence Suppression by Cardiac-Cycle-Inspired
    Driving of Pipe Flow.” <i>Nature</i>, vol. 621, no. 7977, Springer Nature, 2023,
    pp. 71–74, doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>.
  short: D. Scarselli, J.M. Lopez Alonso, A. Varshney, B. Hof, Nature 621 (2023) 71–74.
corr_author: '1'
date_created: 2023-09-17T22:01:09Z
date_published: 2023-09-07T00:00:00Z
date_updated: 2025-09-09T12:59:04Z
day: '07'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1038/s41586-023-06399-5
external_id:
  isi:
  - '001168947700009'
  pmid:
  - '37673988'
file:
- access_level: open_access
  checksum: 9c9f172ba0a9a301d76fff4229812464
  content_type: application/pdf
  creator: dernst
  date_created: 2024-06-04T09:24:34Z
  date_updated: 2024-06-04T09:24:34Z
  file_id: '17118'
  file_name: 2023_submittedversion.pdf
  file_size: 3247252
  relation: main_file
  success: 1
file_date_updated: 2024-06-04T09:24:34Z
fulldoi: https://doi.org/10.1038/s41586-023-06399-5
has_accepted_license: '1'
intvolume: '       621'
isi: 1
issue: '7977'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 71-74
pmid: 1
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
  grant_number: '662960'
  name: Revisiting the Turbulence Problem Using Statistical Mechanics
- _id: 238B8092-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: I04188
  name: Instabilities in pulsating pipe flow in complex fluids
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://www.ista.ac.at/en/news/pumping-like-the-heart/
scopus_import: '1'
status: public
title: Turbulence suppression by cardiac-cycle-inspired driving of pipe flow
type: journal_article
user_id: 317138e5-6ab7-11ef-aa6d-ffef3953e345
volume: 621
year: '2023'
...